HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Bruxelles-National

$516+ Cheap flights from Panama City (PTY) to Bruxelles-National (BRU)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/10. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — BRU
Aug 5 — Aug 121
Tue 8/5
Tue 8/12
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Panama City to Bruxelles-National with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheapflights Tip: The best prices from Panama City Tocumen Intl to Brussels Bruxelles-National are usually found in January or February, booked 62 days in advance, depart on a Monday or Saturday and return on a Tuesday

Cheap flight deals from Panama City to Bruxelles-National

Discover tips and strategies to find the most affordable flight options for your journey from Panama City (PTY) to Bruxelles-National (BRU). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated July 31, 2025.

Round-trip from

$785
(Iberia)

One-way from

$516
(Turkish Airlines)

Popular in

July

Cheapest in

January

Average price

$957
From Panama City Tocumen Intl to Brussels Bruxelles-National
Search Deals
One-way flight from Panama City Tocumen Intl to Brussels Bruxelles-National
Search Deals
Highest demand for flights based on searches. 7% potential increase in price ($67 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 1% potential price decrease ($9 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in July 2025
Search Deals

Find flight deals from Panama City to Bruxelles-National

Cheapest flights from Panama City to Bruxelles-National
Explore the most affordable flight options available from Panama City to Bruxelles-National. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 31, 2025.

This Iberia deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Iberia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/106:20 pmPTY - BRU
1 stop14h 25mIberia
Wed 2/47:00 amBRU - PTY
1 stop15h 45mIberia
Deal found 7/31$785
This Turkish Airlines deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Turkish Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/109:45 pmPTY - BRU
1 stop37h 35mTurkish Airlines
Wed 2/46:20 pmBRU - PTY
2 stops28h 45mTurkish Airlines
Deal found 7/30$827
This Air Europa deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Europa is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/258:25 pmPTY - BRU
1 stop14h 15mAir Europa
Thu 10/96:55 pmBRU - PTY
1 stop30h 45mAir Europa
Deal found 7/31$892
This KLM deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/276:45 pmPTY - BRU
1 stop13h 30mKLM
Sat 1/36:15 amBRU - PTY
1 stop16h 15mKLM
Deal found 7/31$933
This Iberia deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Iberia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/105:55 pmPTY - BRU
2 stops19h 05mMultiple Airlines
Wed 2/47:00 amBRU - PTY
2 stops23h 20mMultiple Airlines
Deal found 7/31$1,000
This United Airlines deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/179:45 amPTY - BRU
1 stop14h 15mUnited Airlines
Wed 10/110:00 amBRU - PTY
2 stops34h 50mUnited Airlines
Deal found 7/30$1,062

Cheapflights Fare Finder

 
Customize your flight search to find flights from Panama City to Bruxelles-National that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 31, 2025.
Use the filters below to find and compare flights from Panama City to Brussels Bruxelles-National Airport that are best for you.

Fly from

Panama City

Fly to

Bruxelles-National

Route

Depart

Return

Price

Panama CityBrussels

PTY - BRU

PTYBRU

Panama City Tocumen Intl

Mon 11/10

6:20 pm-2:45 pm

1 stop14h 25m

Brussels Bruxelles-National

Wed 2/4

7:00 am-4:45 pm

1 stop15h 45m

$785

Panama CityBrussels

PTY - BRU

PTYBRU

Panama City Tocumen Intl

Mon 11/10

9:45 pm-5:20 pm

1 stop37h 35m

Brussels Bruxelles-National

Wed 2/4

6:20 pm-5:05 pm

2 stops28h 45m

$827

Panama CityBrussels

PTY - BRU

PTYBRU

Panama City Tocumen Intl

Thu 9/25

8:25 pm-5:40 pm

1 stop14h 15m

Brussels Bruxelles-National

Thu 10/9

6:55 pm-6:40 pm

1 stop30h 45m

$892

Panama CityBrussels

PTY - BRU

PTYBRU

Panama City Tocumen Intl

Thu 11/27

6:45 pm-2:15 pm

1 stop13h 30m

Brussels Bruxelles-National

Sat 1/3

6:15 am-4:30 pm

1 stop16h 15m

$933

Panama CityBrussels

PTY - BRU

PTYBRU

Panama City Tocumen Intl

Mon 11/10

5:55 pm-7:00 pm

2 stops19h 05m

Brussels Bruxelles-National

Wed 2/4

7:00 am-12:20 am

2 stops23h 20m

$1,000

Panama CityBrussels

PTY - BRU

PTYBRU

Panama City Tocumen Intl

Wed 9/17

9:45 am-7:00 am

1 stop14h 15m

Brussels Bruxelles-National

Wed 10/1

10:00 am-1:50 pm

2 stops34h 50m

$1,062

Panama CityBrussels

PTY - BRU

PTYBRU

Panama City Tocumen Intl

Sun 8/10

9:55 pm-10:10 am

1 stop29h 15m

$516

Panama CityBrussels

PTY - BRU

PTYBRU

Panama City Tocumen Intl

Wed 1/7

6:30 pm-10:15 am

2 stops33h 45m

$767

Panama CityBrussels

PTY - BRU

PTYBRU

Panama City Tocumen Intl

Sun 8/17

8:25 pm-5:40 pm

1 stop14h 15m

$802

Panama CityBrussels

PTY - BRU

PTYBRU

Panama City Tocumen Intl

Sun 8/17

5:10 pm-2:45 pm

1 stop14h 35m

$823

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/31

Showing 1-10 of 11 results
1
2

Best time to book a flight from Panama City to Bruxelles-National

Have a flexible travel schedule? Discover the best time to fly to Bruxelles-National from Panama City with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Panama City to Brussels Bruxelles-National Airport

How far ahead should I book a flight from Panama City to Brussels Bruxelles-National Airport?

Use this chart to determine the optimal time to book a round-trip flight from Panama City to Bruxelles-National. Price data was last updated on July 25, 2025.

The price you pay for your flight from Panama City to Brussels Bruxelles-National Airport may vary depending on when you book. For the best chance of a lower fare, look to book 62 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.

What is the cheapest month to book a flight from Panama City to Brussels Bruxelles-National Airport?

Currently, November is the cheapest month in which you can book a flight from Panama City to Brussels Bruxelles-National Airport (average of $614). Flying from Panama City to Brussels Bruxelles-National Airport in June is currently the most expensive (average of $1,081). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from PTY to BRU?

Find hourly flight availability from Panama City to Bruxelles-National. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated July 31, 2025.

A simple way to save on the total cost of your ticket is to fly from Panama City to Brussels Bruxelles-National Airport in the afternoon. If you’re flexible enough to do this you can expect to save up to 17% on your trip compared to booking a flight at noon.

How much does it cost to fly round-trip from Panama City to Brussels Bruxelles-National Airport?

Reviews of airlines servicing Bruxelles-National

Get insights into the airlines that provide service to Bruxelles-National. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Bruxelles-National. Reviews last updated July 31, 2025.
Read reviews from past customers who have flown KLM, United Airlines, and Turkish Airlines from Panama City to Brussels Bruxelles-National Airport. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
KLM
7.8
Good
1,383 reviews

Entertainment

7.1

Boarding

7.8

Food

7.3

Overall

7.8

Crew

8.4

Comfort

7.7

Reviews

1 / 20
4.0
Okay

Anonymous,Jun 2025

AMS - BOS

A two and half hour delay caused havoc with all connections. Otherwise on board service was great.
KLM
7.8
Good
1,383 reviews
KLM
7.8
Good
1,383 reviews

Entertainment

7.1

Boarding

7.8

Food

7.3

Overall

7.8

Crew

8.4

Comfort

7.7

Reviews

1 / 20
4.0
Okay

Anonymous,Jun 2025

AMS - BOS

A two and half hour delay caused havoc with all connections. Otherwise on board service was great.
United Airlines
7.4
Good
8,900 reviews
KLM
7.8
Good
1,383 reviews

Entertainment

7.1

Boarding

7.8

Food

7.3

Overall

7.8

Crew

8.4

Comfort

7.7

Reviews

1 / 20
4.0
Okay

Anonymous,Jun 2025

AMS - BOS

A two and half hour delay caused havoc with all connections. Otherwise on board service was great.
Turkish Airlines
7.3
Good
3,933 reviews
KLM
7.8
Good
1,383 reviews

Entertainment

7.1

Boarding

7.8

Food

7.3

Overall

7.8

Crew

8.4

Comfort

7.7

Reviews

1 / 20
4.0
Okay

Anonymous,Jun 2025

AMS - BOS

A two and half hour delay caused havoc with all connections. Otherwise on board service was great.
Air Europa
7.0
Good
543 reviews
KLM
7.8
Good
1,383 reviews

Entertainment

7.1

Boarding

7.8

Food

7.3

Overall

7.8

Crew

8.4

Comfort

7.7

Reviews

1 / 20
4.0
Okay

Anonymous,Jun 2025

AMS - BOS

A two and half hour delay caused havoc with all connections. Otherwise on board service was great.
Iberia
7.0
Good
2,859 reviews
KLM
7.8
Good
1,383 reviews

Entertainment

7.1

Boarding

7.8

Food

7.3

Overall

7.8

Crew

8.4

Comfort

7.7

Reviews

1 / 20
4.0
Okay

Anonymous,Jun 2025

AMS - BOS

A two and half hour delay caused havoc with all connections. Otherwise on board service was great.

Related info for your journey

Find useful and relevant information for your journey from Panama City to Bruxelles-National. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Panama City to Brussels Bruxelles-National?

    If you book a flight to Brussels Bruxelles-National from Panama City, you will be flying from Tocumen Intl, which is the city’s only airport. Panama City Tocumen Intl (PTY) is located 11.4 mi from the center of Panama City. There are 0 flights from Tocumen Intl to Brussels Bruxelles-National per day from 2 different airlines.

  • What are the cheapest airlines flying from Panama City to Brussels Bruxelles-National Airport round-trip?

    Flying on Iberia is currently your cheapest option to Brussels Bruxelles-National Airport, with prices starting at $785. Additional round-trip tickets that might be worth considering are offered by Turkish Airlines and Air Europa, with the lowest prices starting at $827 and $892, respectively. Iberia is 8% cheaper than the average price of flights available within the next 90 days to this destination.

  • What are the cheapest airlines to fly from Panama City to Brussels Bruxelles-National Airport one-way?

    The cheapest airline one-way is Turkish Airlines, with whom users have recently found tickets for as low as $516. However, be on the lookout for offers from Air Europa and Iberia, as they are both options that can get you from Panama City to Brussels Bruxelles-National Airport for a low price.

  • Can I find deals for flights from Panama City to Bruxelles-National that include hotel bookings?

    Yes. In addition to deals on Panama City to Bruxelles-National flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Panama City to Bruxelles-National?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama City to Bruxelles-National.

  • Can I find deals for business class flights from Panama City to Bruxelles-National?

    Yes. Cheapflights offers flight deals from Panama City to Bruxelles-National by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Panama City to Brussels Bruxelles-National Airport?

    Currently, November is the cheapest month in which you can book a flight from Panama City to Brussels Bruxelles-National Airport (average of $614). Flying from Panama City to Brussels Bruxelles-National Airport in June is currently the most expensive (average of $1,081). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Brussels Bruxelles-National Airport?

Book flights to Brussels Bruxelles-National Airport if you plan to visit one of these locations
Charleroi
Mons
Mechelen
Zaventem
Spa

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Other flights to Bruxelles-National

Explore flights to Bruxelles-National departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on July 31, 2025.
Newark to Bruxelles-National flights
John F Kennedy Intl to Bruxelles-National flights
Atlanta to Bruxelles-National flights
Dulles Intl to Bruxelles-National flights
O'Hare Intl to Bruxelles-National flights
Boston to Bruxelles-National flights
Brussels Bruxelles-National Airport to Dublin flights
Brussels Bruxelles-National Airport to Barcelona-El Prat Airport flights
Brussels Bruxelles-National Airport to Palma de Mallorca flights
Brussels Bruxelles-National Airport to Porto flights
Brussels Bruxelles-National Airport to Bilbao flights
Brussels Bruxelles-National Airport to Valencia flights
Brussels Bruxelles-National Airport to Milan Linate Airport flights
Brussels Bruxelles-National Airport to Florence flights
Brussels Bruxelles-National Airport to Nador flights
Brussels Bruxelles-National Airport to Geneva flights
Brussels Bruxelles-National Airport to Rome Fiumicino Airport flights
Brussels Bruxelles-National Airport to Venice Marco Polo Airport flights
Brussels Bruxelles-National Airport to Milan Malpensa Airport flights
Brussels Bruxelles-National Airport to Barcelona-El Prat Airport flights
Brussels Bruxelles-National Airport to Vienna flights
Brussels Bruxelles-National Airport to Hamburg flights
Brussels Bruxelles-National Airport to Lisbon flights
Brussels Bruxelles-National Airport to Rome Fiumicino Airport flights

Top 2 airlines flying from Panama City to Bruxelles-National

Discover the top 2 airlines that operate flights from Panama City to Bruxelles-National. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 31, 2025.
AirlineCheapestAverageFlexibilityOn-time
Air EuropaCheapest$743Average$901FlexibilityNo cancel feeOn-time83%
Air FranceCheapest$785Average$1,039FlexibilityNo cancel feeOn-time77%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.