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Bruxelles-National

$647+ Cheap flights from Panama City (PTY) to Bruxelles-National (BRU)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/14. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — BRU
Feb 28 — Mar 71
Sat 2/28
Sat 3/7
1 adult, Economy
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Cheap flight deals from Panama City to Bruxelles-National

Cheapest flights from Panama City to Bruxelles-National
Explore the most affordable flight options available from Panama City to Bruxelles-National. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 29, 2026.

This Turkish Airlines deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Turkish Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/149:45 pm
PTY
-
BRU
1 stop37h 35m
Turkish Airlines
Thu 2/263:15 pm
BRU
-
PTY
2 stops31h 50m
Turkish Airlines
Deal found 1/26$740
This Turkish Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Turkish Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/1110:20 pm
PTY
-
BRU
1 stop40h 05m
Turkish Airlines
Tue 5/52:25 pm
BRU
-
PTY
1 stop37h 00m
Turkish Airlines
Deal found 1/27$784
This FlightHub deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/1110:20 pm
PTY
-
BRU
1 stop32h 05m
Turkish Airlines
Sun 5/36:55 pm
BRU
-
PTY
1 stop32h 30m
Turkish Airlines
Deal found 1/27$795
This Turkish Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Turkish Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/29:45 pm
PTY
-
BRU
1 stop34h 30m
Turkish Airlines
Mon 3/236:20 pm
BRU
-
PTY
2 stops28h 45m
Turkish Airlines
Deal found 1/27$796
This FlightHub deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/128:05 pm
PTY
-
BRU
1 stop18h 20m
Turkish Airlines
Mon 5/47:20 am
BRU
-
PTY
1 stop20h 05m
Turkish Airlines
Deal found 1/27$806
This FlightHub deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/29:45 pm
PTY
-
BRU
1 stop30h 50m
Turkish Airlines
Sat 3/216:20 pm
BRU
-
PTY
2 stops28h 45m
Turkish Airlines
Deal found 1/27$807
This Turkish Airlines deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Turkish Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/1310:20 pm
PTY
-
BRU
1 stop36h 35m
Turkish Airlines
Sat 4/257:20 am
BRU
-
PTY
1 stop20h 05m
Turkish Airlines
Deal found 1/28$814
This Turkish Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Turkish Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/29:45 pm
PTY
-
BRU
1 stop34h 30m
Turkish Airlines
Sun 3/294:15 pm
BRU
-
PTY
1 stop35h 10m
Turkish Airlines
Deal found 1/27$815

Find flight deals from Panama City to Bruxelles-National

Discover tips and strategies to find the most affordable flight options for your journey from Panama City (PTY) to Bruxelles-National (BRU). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated January 29, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$740
(Turkish Airlines)

One-way from

$647
(FlightHub)

Popular in

December

Cheapest in

February

Average price

$861
Provider with most accurate pricing for Panama City Tocumen Intl-Brussels Bruxelles-National flight deals.
Search Deals
Provider most trusted by Cheapflights users for Panama City Tocumen Intl-Brussels Bruxelles-National flights.
Search Deals
From Panama City Tocumen Intl to Brussels Bruxelles-National
Search Deals
One-way flight from Panama City Tocumen Intl to Brussels Bruxelles-National
Search Deals
Highest demand for flights based on searches. 7% potential increase in price ($68 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 1% potential price decrease ($15 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in January 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Panama City to Bruxelles-National that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 29, 2026.
Use the filters below to find and compare flights from Panama City to Brussels Bruxelles-National Airport that are best for you.

Fly from

Panama City

Fly to

Bruxelles-National

Route

Depart

Return

Price

Panama CityBrussels

PTY - BRU

PTYBRU

Panama City Tocumen Intl

Sat 2/14

9:45 pm-5:20 pm

1 stop37h 35m

Brussels Bruxelles-National

Thu 2/26

3:15 pm-5:05 pm

2 stops31h 50m

$740

Panama CityBrussels

PTY - BRU

PTYBRU

Panama City Tocumen Intl

Sat 4/11

10:20 pm-9:25 pm

1 stop40h 05m

Brussels Bruxelles-National

Tue 5/5

2:25 pm-8:25 pm

1 stop37h 00m

$784

Panama CityBrussels

PTY - BRU

PTYBRU

Panama City Tocumen Intl

Mon 3/2

9:45 pm-10:10 pm

1 stop18h 25m

Brussels Bruxelles-National

Wed 3/25

6:20 pm-5:05 pm

2 stops28h 45m

$796

Panama CityBrussels

PTY - BRU

PTYBRU

Panama City Tocumen Intl

Mon 3/2

9:45 pm-2:15 pm

1 stop34h 30m

Brussels Bruxelles-National

Mon 3/23

6:20 pm-5:05 pm

2 stops28h 45m

$796

Panama CityBrussels

PTY - BRU

PTYBRU

Panama City Tocumen Intl

Mon 4/13

10:20 pm-5:55 pm

1 stop36h 35m

Brussels Bruxelles-National

Sat 4/25

7:20 am-8:25 pm

1 stop20h 05m

$814

Panama CityBrussels

PTY - BRU

PTYBRU

Panama City Tocumen Intl

Mon 3/2

9:45 pm-5:20 pm

1 stop37h 35m

Brussels Bruxelles-National

Sun 3/29

6:55 pm-8:25 pm

1 stop32h 30m

$815

Panama CityBrussels

PTY - BRU

PTYBRU

Panama City Tocumen Intl

Sat 3/14

9:45 pm-10:10 pm

1 stop18h 25m

Brussels Bruxelles-National

Wed 4/8

7:20 am-8:25 pm

1 stop20h 05m

$858

Panama CityBrussels

PTY - BRU

PTYBRU

Panama City Tocumen Intl

Tue 7/14

8:25 pm-9:45 am

1 stop30h 20m

$647

Panama CityBrussels

PTY - BRU

PTYBRU

Panama City Tocumen Intl

Tue 7/14

8:05 pm-10:10 am

1 stop31h 05m

$690

Panama CityBrussels

PTY - BRU

PTYBRU

Panama City Tocumen Intl

Tue 7/14

5:25 pm-10:30 pm

2 stops22h 05m

$731

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/28

Compare providers for flights from Panama City to Bruxelles-National

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Panama City to Bruxelles-National in January.
ProviderPrice AccuracyTrust Score*
FlightHubPrice Accuracy3 starsTrust Score*3 stars
Trip.comPrice Accuracy1 starTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Panama City-Brussels Bruxelles-National Airport flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Panama City-Brussels Bruxelles-National Airport flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Panama City-Brussels Bruxelles-National Airport flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Panama City-Brussels Bruxelles-National Airport flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Panama City-Brussels Bruxelles-National Airport flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Panama City to Bruxelles-National

Have a flexible travel schedule? Discover the best time to fly to Bruxelles-National from Panama City with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Panama City to Brussels Bruxelles-National Airport

How far ahead should I book a flight from Panama City to Brussels Bruxelles-National Airport?

Use this chart to determine the optimal time to book a round-trip flight from Panama City to Bruxelles-National. Price data was last updated on January 23, 2026.

The price you pay for your flight from Panama City to Brussels Bruxelles-National Airport may vary depending on when you book. For the best chance of a lower fare, look to book 49 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.

What is the cheapest month to book a flight from Panama City to Brussels Bruxelles-National Airport?

Currently, May is the cheapest month in which you can book a flight from Panama City to Brussels Bruxelles-National Airport (average of $685). Flying from Panama City to Brussels Bruxelles-National Airport in December is currently the most expensive (average of $848). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Bruxelles-National

Get insights into the airlines that provide service to Bruxelles-National. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Bruxelles-National. Reviews last updated January 29, 2026.
Read reviews from past customers who have flown Air France and Air Europa from Panama City to Brussels Bruxelles-National Airport. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Air France
7.4
Good
1,528 reviews

Entertainment

7.0

Crew

8.1

Comfort

7.3

Overall

7.4

Boarding

7.4

Food

7.0

Reviews

1 / 20
6.0
Good

Jayesh,Jan 2026

CDG - NMI

Entertainment needs more good Bollywood movies - as this flight was going to Mumbai, India. The Aircraft was a OLD - Is service to India cannot be improved ? The aircraft from Newark to Paris was great n new aircraft BUT aircraft from Paris to Mumbai was very old and poor class
Air France
7.4
Good
1,528 reviews
Air France
7.4
Good
1,528 reviews

Entertainment

7.0

Crew

8.1

Comfort

7.3

Overall

7.4

Boarding

7.4

Food

7.0

Reviews

1 / 20
6.0
Good

Jayesh,Jan 2026

CDG - NMI

Entertainment needs more good Bollywood movies - as this flight was going to Mumbai, India. The Aircraft was a OLD - Is service to India cannot be improved ? The aircraft from Newark to Paris was great n new aircraft BUT aircraft from Paris to Mumbai was very old and poor class
Air Europa
6.9
Okay
587 reviews
Air France
7.4
Good
1,528 reviews

Entertainment

7.0

Crew

8.1

Comfort

7.3

Overall

7.4

Boarding

7.4

Food

7.0

Reviews

1 / 20
6.0
Good

Jayesh,Jan 2026

CDG - NMI

Entertainment needs more good Bollywood movies - as this flight was going to Mumbai, India. The Aircraft was a OLD - Is service to India cannot be improved ? The aircraft from Newark to Paris was great n new aircraft BUT aircraft from Paris to Mumbai was very old and poor class

Related info for your journey

Find useful and relevant information for your journey from Panama City to Bruxelles-National. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Panama City to Brussels Bruxelles-National?

    If you book a flight to Brussels Bruxelles-National from Panama City, you will be flying from Tocumen Intl, which is the city’s only airport. Panama City Tocumen Intl (PTY) is located 11.4 mi from the center of Panama City. There are 0 flights from Tocumen Intl to Brussels Bruxelles-National per day from 2 different airlines.

  • How long is the flight from Panama City to Brussels Bruxelles-National Airport?

    Departing from Panama City to Brussels Bruxelles-National Airport will take you 37h 35m. The distance from Panama City to Brussels Bruxelles-National Airport is about 5462 mi.

  • What are the cheapest airlines flying from Panama City to Brussels Bruxelles-National Airport round-trip?

    Flying on Air France is currently your cheapest option to Brussels Bruxelles-National Airport, with prices starting at $785. Another option worth looking into is Air Europa, starting at $797 round trip. Air France is 12% cheaper than the average price of flights available within the next 90 days to this destination.

  • Can I find deals for flights from Panama City to Bruxelles-National that include hotel bookings?

    Yes. In addition to deals on Panama City to Bruxelles-National flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Panama City to Bruxelles-National?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama City to Bruxelles-National.

  • Can I find deals for business class flights from Panama City to Bruxelles-National?

    Yes. Cheapflights offers flight deals from Panama City to Bruxelles-National by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Panama City to Brussels Bruxelles-National Airport?

    Currently, May is the cheapest month in which you can book a flight from Panama City to Brussels Bruxelles-National Airport (average of $685). Flying from Panama City to Brussels Bruxelles-National Airport in December is currently the most expensive (average of $848). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Brussels Bruxelles-National Airport?

Book flights to Brussels Bruxelles-National Airport if you plan to visit one of these locations
Mons
Hasselt
Charleroi
Mechelen
Zaventem

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Other flights to Bruxelles-National

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Top 2 airlines flying from Panama City to Bruxelles-National

Discover the top 2 airlines that operate flights from Panama City to Bruxelles-National. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 29, 2026.
AirlineCheapestAverageFlexibilityOn-time
Air FranceCheapest$785Average$1,039FlexibilityNo cancel feeOn-time77%
Air EuropaCheapest$797Average$932FlexibilityNo cancel feeOn-time83%

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