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Bruxelles-National

$712+ Cheap flights from Panama City (PTY) to Bruxelles-National (BRU)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/10. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — BRU
Oct 15 — Oct 221
Wed 10/15
Wed 10/22
1 adult, Economy
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Cheapflights Tip: The best prices from Panama City Tocumen Intl to Brussels Bruxelles-National are usually found in January or February, booked 42 days in advance, depart on a Monday or Saturday and return on a Tuesday

Cheap flight deals from Panama City to Bruxelles-National

Discover tips and strategies to find the most affordable flight options for your journey from Panama City (PTY) to Bruxelles-National (BRU). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 15, 2025.

Round-trip from

$712
(Iberia)

Popular in

December

Cheapest in

January

Average price

$955
From Panama City Tocumen Intl to Brussels Bruxelles-National
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High demand for flights, 0% potential price rise
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Cheapest flight prices on average. 1% potential price decrease ($11 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Find flight deals from Panama City to Bruxelles-National

Cheapest flights from Panama City to Bruxelles-National
Explore the most affordable flight options available from Panama City to Bruxelles-National. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 15, 2025.

This Iberia deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Iberia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/106:20 pmPTY - BRU
1 stop22h 15mIberia
Wed 2/47:00 amBRU - PTY
1 stop15h 45mIberia
Deal found 9/14$712
This FlightHub deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/109:30 pmPTY - BRU
1 stop14h 15mAir Europa
Wed 2/46:55 pmBRU - PTY
1 stop30h 50mAir Europa
Deal found 9/15$724
This Turkish Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Turkish Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/109:45 pmPTY - BRU
1 stop37h 35mTurkish Airlines
Wed 2/46:20 pmBRU - PTY
2 stops28h 45mTurkish Airlines
Deal found 9/15$837
This FlightHub deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/279:30 pmPTY - BRU
1 stop14h 15mAir Europa
Sat 1/36:55 pmBRU - PTY
1 stop30h 50mAir Europa
Deal found 9/14$948
This FlightHub deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/289:30 pmPTY - BRU
1 stop30h 20mAir Europa
Sat 1/310:45 amBRU - PTY
1 stop15h 00mAir Europa
Deal found 9/14$991
This Iberia deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Iberia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/109:45 amPTY - BRU
2 stops19h 45mMultiple Airlines
Wed 2/412:10 pmBRU - PTY
2 stops18h 30mMultiple Airlines
Deal found 9/14$1,012
This Turkish Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Turkish Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/19:55 pmPTY - BRU
1 stop32h 30mTurkish Airlines
Mon 10/66:50 pmBRU - PTY
2 stops30h 30mTurkish Airlines
Deal found 9/15$1,037
This Iberia deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Iberia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/177:55 amPTY - BRU
2 stops23h 50mIberia
Wed 10/17:05 amBRU - PTY
2 stops20h 10mIberia
Deal found 9/15$1,059
This KLM deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/256:50 pmPTY - BRU
1 stop12h 45mKLM
Thu 10/910:25 amBRU - PTY
1 stop13h 25mKLM
Deal found 9/15$1,069
This Turkish Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Turkish Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/286:45 pmPTY - BRU
1 stop21h 25mTurkish Airlines
Sat 1/36:20 pmBRU - PTY
2 stops28h 45mTurkish Airlines
Deal found 9/15$1,085
This Turkish Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Turkish Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/276:45 pmPTY - BRU
1 stop37h 30mTurkish Airlines
Sat 1/36:20 pmBRU - PTY
2 stops28h 45mTurkish Airlines
Deal found 9/15$1,089

Cheapflights Fare Finder

 
Customize your flight search to find flights from Panama City to Bruxelles-National that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 15, 2025.
Use the filters below to find and compare flights from Panama City to Brussels Bruxelles-National Airport that are best for you.

Fly from

Panama City

Fly to

Bruxelles-National

Route

Depart

Return

Price

Panama CityBrussels

PTY - BRU

PTYBRU

Panama City Tocumen Intl

Mon 11/10

9:30 pm-5:45 pm

1 stop14h 15m

Brussels Bruxelles-National

Wed 2/4

6:55 pm-7:45 pm

1 stop30h 50m

$724

Panama CityBrussels

PTY - BRU

PTYBRU

Panama City Tocumen Intl

Sun 2/8

9:30 pm-5:45 pm

1 stop14h 15m

Brussels Bruxelles-National

Thu 2/12

10:45 am-7:45 pm

1 stop15h 00m

$777

Panama CityBrussels

PTY - BRU

PTYBRU

Panama City Tocumen Intl

Mon 11/10

9:45 pm-2:15 pm

1 stop34h 30m

Brussels Bruxelles-National

Wed 2/4

3:15 pm-5:05 pm

2 stops31h 50m

$837

Panama CityBrussels

PTY - BRU

PTYBRU

Panama City Tocumen Intl

Sat 2/14

9:45 pm-5:20 pm

1 stop37h 35m

Brussels Bruxelles-National

Thu 2/26

3:15 pm-5:05 pm

2 stops31h 50m

$837

Panama CityBrussels

PTY - BRU

PTYBRU

Panama City Tocumen Intl

Sun 2/8

10:20 pm-2:15 pm

2 stops33h 55m

Brussels Bruxelles-National

Thu 2/12

10:45 am-4:30 pm

1 stop35h 45m

$928

Panama CityBrussels

PTY - BRU

PTYBRU

Panama City Tocumen Intl

Sat 2/14

9:45 am-4:20 pm

2 stops24h 35m

Brussels Bruxelles-National

Thu 2/26

9:55 pm-12:40 am

2 stops32h 45m

$980

Panama CityBrussels

PTY - BRU

PTYBRU

Panama City Tocumen Intl

Wed 10/1

9:55 pm-5:50 pm

1 stop36h 55m

Brussels Bruxelles-National

Mon 10/6

7:15 am-6:20 pm

2 stops42h 05m

$1,037

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/15

Best time to book a flight from Panama City to Bruxelles-National

Have a flexible travel schedule? Discover the best time to fly to Bruxelles-National from Panama City with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Panama City to Brussels Bruxelles-National Airport

How far ahead should I book a flight from Panama City to Brussels Bruxelles-National Airport?

Use this chart to determine the optimal time to book a round-trip flight from Panama City to Bruxelles-National. Price data was last updated on September 12, 2025.

The price you pay for your flight from Panama City to Brussels Bruxelles-National Airport may vary depending on when you book. For the best chance of a lower fare, look to book 42 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.

What is the cheapest month to book a flight from Panama City to Brussels Bruxelles-National Airport?

Currently, November is the cheapest month in which you can book a flight from Panama City to Brussels Bruxelles-National Airport (average of $614). Flying from Panama City to Brussels Bruxelles-National Airport in June is currently the most expensive (average of $1,077). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from PTY to BRU?

Find hourly flight availability from Panama City to Bruxelles-National. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 15, 2025.

A simple way to save on the total cost of your ticket is to fly from Panama City to Brussels Bruxelles-National Airport in the afternoon. If you’re flexible enough to do this you can expect to save up to 17% on your trip compared to booking a flight at noon.

Reviews of airlines servicing Bruxelles-National

Get insights into the airlines that provide service to Bruxelles-National. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Bruxelles-National. Reviews last updated September 15, 2025.
Read reviews from past customers who have flown Air France and Air Europa from Panama City to Brussels Bruxelles-National Airport. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Air France
7.4
Good
1,469 reviews

Comfort

7.4

Food

7.0

Overall

7.4

Boarding

7.4

Crew

8.2

Entertainment

7.0

Reviews

1 / 20
10.0
Excellent

SYLVIA,Apr 2025

TLV - CDG

A newer plane. The flight from TelAviv to Paris was on a new aircraft, wider seat. ,more privacy. Nice toilets. The flight from Paris to Santiago Chile was on a very old aircraft. Awful toilets, outmoded sits etc.
Air France
7.4
Good
1,469 reviews
Air France
7.4
Good
1,469 reviews

Comfort

7.4

Food

7.0

Overall

7.4

Boarding

7.4

Crew

8.2

Entertainment

7.0

Reviews

1 / 20
10.0
Excellent

SYLVIA,Apr 2025

TLV - CDG

A newer plane. The flight from TelAviv to Paris was on a new aircraft, wider seat. ,more privacy. Nice toilets. The flight from Paris to Santiago Chile was on a very old aircraft. Awful toilets, outmoded sits etc.
Air Europa
7.0
Good
556 reviews
Air France
7.4
Good
1,469 reviews

Comfort

7.4

Food

7.0

Overall

7.4

Boarding

7.4

Crew

8.2

Entertainment

7.0

Reviews

1 / 20
10.0
Excellent

SYLVIA,Apr 2025

TLV - CDG

A newer plane. The flight from TelAviv to Paris was on a new aircraft, wider seat. ,more privacy. Nice toilets. The flight from Paris to Santiago Chile was on a very old aircraft. Awful toilets, outmoded sits etc.

Related info for your journey

Find useful and relevant information for your journey from Panama City to Bruxelles-National. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Panama City to Brussels Bruxelles-National?

    If you book a flight to Brussels Bruxelles-National from Panama City, you will be flying from Tocumen Intl, which is the city’s only airport. Panama City Tocumen Intl (PTY) is located 11.4 mi from the center of Panama City. There are 0 flights from Tocumen Intl to Brussels Bruxelles-National per day from 2 different airlines.

  • How long is the flight from Panama City to Brussels Bruxelles-National Airport?

    Departing from Panama City to Brussels Bruxelles-National Airport will take you 14h 15m. The distance from Panama City to Brussels Bruxelles-National Airport is about 5462 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines flying from Panama City to Brussels Bruxelles-National Airport round-trip?

    Flying on Air France is currently your cheapest option to Brussels Bruxelles-National Airport, with prices starting at $785. Another option worth looking into is Air Europa, starting at $797 round trip. Air France is 9% cheaper than the average price of flights available within the next 90 days to this destination.

  • Can I find deals for flights from Panama City to Bruxelles-National that include hotel bookings?

    Yes. In addition to deals on Panama City to Bruxelles-National flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Panama City to Bruxelles-National?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama City to Bruxelles-National.

  • Can I find deals for business class flights from Panama City to Bruxelles-National?

    Yes. Cheapflights offers flight deals from Panama City to Bruxelles-National by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Panama City to Brussels Bruxelles-National Airport?

    Currently, November is the cheapest month in which you can book a flight from Panama City to Brussels Bruxelles-National Airport (average of $614). Flying from Panama City to Brussels Bruxelles-National Airport in June is currently the most expensive (average of $1,077). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Brussels Bruxelles-National Airport?

Book flights to Brussels Bruxelles-National Airport if you plan to visit one of these locations
Charleroi
Mons
Mechelen
Zaventem

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Top 2 airlines flying from Panama City to Bruxelles-National

Discover the top 2 airlines that operate flights from Panama City to Bruxelles-National. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 15, 2025.
AirlineCheapestAverageFlexibilityOn-time
Air FranceCheapest$785Average$1,039FlexibilityNo cancel feeOn-time77%
Air EuropaCheapest$797Average$904FlexibilityNo cancel feeOn-time83%

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