$553+ Cheap flights from Panama City (PTY) to Bruxelles-National (BRU)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/25. Fares are subject to change and may not be available on all flights or dates of travel.
Find cheap flights from Panama City to Bruxelles-National with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheapflights Tip: The best prices from Panama City Tocumen Intl to Brussels Bruxelles-National are usually found in January or March, booked 42 days in advance, depart on a Monday or Saturday and return on a Tuesday
Cheap flight deals from Panama City to Bruxelles-National
Cheapest flights from Panama City to Bruxelles-NationalExplore the most affordable flight options available from Panama City to Bruxelles-National. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 18, 2025.
Explore the most affordable flight options available from Panama City to Bruxelles-National. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 18, 2025.
This KLM deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
This KLM deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Find flight deals from Panama City to Bruxelles-National
Discover tips and strategies to find the most affordable flight options for your journey from Panama City (PTY) to Bruxelles-National (BRU). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated December 18, 2025.
Most accurate provider | eDreams 3 stars |
|---|---|
Most trusted provider | eDreams 3 stars |
Round-trip from | $750 (Turkish Airlines) |
One-way from | $553 (Condor) |
Popular in | December |
Cheapest in | January |
Average price | $1,057 |
Cheapflights Fare Finder
Use the filters below to find and compare flights from Panama City to Brussels Bruxelles-National Airport that are best for you.
Fly from
Fly to
Route
Depart
Return
Price
Panama CityBrussels
PTY - BRU
PTYBRU
Panama City Tocumen Intl
Thu 2/12
6:45 pm-10:10 pm
1 stop21h 25m
Brussels Bruxelles-National
Wed 2/25
11:35 am-5:05 pm
2 stops35h 30m
Panama CityBrussels
PTY - BRU
PTYBRU
Panama City Tocumen Intl
Mon 6/1
8:25 pm-5:40 pm
1 stop14h 15m
Brussels Bruxelles-National
Mon 6/15
6:55 pm-6:40 pm
1 stop30h 45m
Panama CityBrussels
PTY - BRU
PTYBRU
Panama City Tocumen Intl
Sat 2/14
10:05 pm-10:20 pm
1 stop18h 15m
Brussels Bruxelles-National
Thu 2/26
8:05 am-4:30 pm
1 stop14h 25m
Panama CityBrussels
PTY - BRU
PTYBRU
Panama City Tocumen Intl
Wed 2/4
8:01 am-6:40 pm
2 stops28h 39m
Brussels Bruxelles-National
Wed 2/18
10:20 am-6:13 am
2 stops25h 53m
Panama CityBrussels
PTY - BRU
PTYBRU
Panama City Tocumen Intl
Sat 2/14
7:55 am-2:30 pm
2 stops24h 35m
Brussels Bruxelles-National
Thu 2/26
10:20 am-6:13 am
2 stops25h 53m
Panama CityBrussels
PTY - BRU
PTYBRU
Panama City Tocumen Intl
Sat 1/17
10:26 am-2:30 pm
2 stops22h 04m
Brussels Bruxelles-National
Fri 1/23
10:20 am-6:37 am
2 stops26h 17m
Panama CityBrussels
PTY - BRU
PTYBRU
Panama City Tocumen Intl
Thu 12/25
7:05 pm-5:30 pm
1 stop16h 25m
Compare providers for flights from Panama City to Bruxelles-National
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Panama City to Bruxelles-National in December.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*1 star | |
| Price Accuracy2 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Panama City-Brussels Bruxelles-National Airport flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Panama City-Brussels Bruxelles-National Airport flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Panama City-Brussels Bruxelles-National Airport flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Panama City-Brussels Bruxelles-National Airport flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Panama City-Brussels Bruxelles-National Airport flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Panama City to Bruxelles-National
Have a flexible travel schedule? Discover the best time to fly to Bruxelles-National from Panama City with our price prediction graph.
Cheapflights Insights
Everything you need to know about your flight from Panama City to Brussels Bruxelles-National Airport
How far ahead should I book a flight from Panama City to Brussels Bruxelles-National Airport?
The price you pay for your flight from Panama City to Brussels Bruxelles-National Airport may vary depending on when you book. For the best chance of a lower fare, look to book 42 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.
What is the cheapest month to book a flight from Panama City to Brussels Bruxelles-National Airport?
Currently, May is the cheapest month in which you can book a flight from Panama City to Brussels Bruxelles-National Airport (average of $685). Flying from Panama City to Brussels Bruxelles-National Airport in December is currently the most expensive (average of $848). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from PTY to BRU?
A simple way to save on the total cost of your ticket is to fly from Panama City to Brussels Bruxelles-National Airport in the evening. If you’re flexible enough to do this you can expect to save up to 16% on your trip compared to booking a flight in the afternoon.
How often are flights from Panama City to Brussels delayed?
About 0% of weekly flights between Panama City and Brussels have experienced delays in the past year, with the average delay time being 0 minutes.
What is the most punctual flight time for Panama City to Brussels flights?
Historically, flights departing in the evening are less likely to be delayed, whereas flights leaving in the evening tend to experience delays more often.
Reviews of airlines servicing Bruxelles-National
Get insights into the airlines that provide service to Bruxelles-National. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Bruxelles-National. Reviews last updated December 18, 2025.
Read reviews from past customers who have flown Air France and Air Europa from Panama City to Brussels Bruxelles-National Airport. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Boarding
Overall
Comfort
Crew
Entertainment
Food
Reviews
Alpha Amadu,Dec 2025
CKY - CDG
Boarding
Overall
Comfort
Crew
Entertainment
Food
Reviews
Alpha Amadu,Dec 2025
CKY - CDG
Boarding
Overall
Comfort
Crew
Entertainment
Food
Reviews
Alpha Amadu,Dec 2025
CKY - CDG
Related info for your journey
Find useful and relevant information for your journey from Panama City to Bruxelles-National. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Other flights to Bruxelles-National
Explore flights to Bruxelles-National departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on December 18, 2025.
Top 2 airlines flying from Panama City to Bruxelles-National
Discover the top 2 airlines that operate flights from Panama City to Bruxelles-National. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 18, 2025.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$785 | Average$1,039 | FlexibilityNo cancel fee | On-time77% | |
| Cheapest$797 | Average$904 | FlexibilityNo cancel fee | On-time83% |