In terms of precipitation, rainfall in Florence, Alabama ranges from 2.9 - 6.1 inches per month. March is typically the wettest month, when rainfall can reach 6.1 in. October is typically the driest time to visit Florence, Alabama when rainfall is around 2.9 in.

If weather is an important factor for your trip to Florence, Alabama, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 78.8 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 41.0 F).

What is the cheapest time of day to fly from ORD to MSL?

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Chicago O'Hare Intl Airport to Florence, Alabama as you normally would.

What airport do you fly into for flights to Florence from Chicago O'Hare Intl?

Most people fly into Florence Muscle Shoals (MSL) if they book a flight to Florence from Chicago O'Hare Intl. On average, Muscle Shoals has 0 inbound flights from Chicago O'Hare Intl per day from 0 airlines. Florence Muscle Shoals is conveniently located just 5.4 mi from Florence’s city center.

Can I find deals for flights from O'Hare Intl to Florence that include hotel bookings?

Yes. In addition to deals on O'Hare Intl to Florence flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from O'Hare Intl to Florence?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from O'Hare Intl to Florence.

Can I find deals for business class flights from O'Hare Intl to Florence?

Yes. Cheapflights offers flight deals from O'Hare Intl to Florence by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$291+ Cheap Flights from Chicago O'Hare Intl Airport to Florence, AL

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Cheap flight deals from O'Hare Intl to Florence

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Cheapest flights from O'Hare Intl to Florence
Explore the most affordable flight options available from O'Hare Intl to Florence. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 30, 2026.

Wed 11/112:55 pm -

2 stops27h 55m

Sun 11/1512:25 pm -

2 stops27h 12m

Deal found 10/27

$503

Find flight deals from O'Hare Intl to Florence

Round-trip from	$503 (Mytrip)
One-way from	$291 (Booking.com)

From Chicago O'Hare Intl to Florence Muscle Shoals

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ChicagoFlorence

ORD Chicago O'Hare Intl - MSL Florence Muscle Shoals

ORDMSL

Chicago O'Hare Intl

Sun 3/14

2:55 pm-6:50 pm

2 stops27h 55m

Florence Muscle Shoals

Wed 12/31

12:00 am-12:00 am

Nonstop0h 00m

$291

Quickest round-trip

ChicagoFlorence

ORD Chicago O'Hare Intl - MSL Florence Muscle Shoals

ORDMSL

Chicago O'Hare Intl

Sun 3/14

5:55 pm-6:50 pm

1 stop24h 55m

Florence Muscle Shoals

Wed 12/31

12:00 am-12:00 am

Nonstop0h 00m

$382

ChicagoFlorence

ORD Chicago O'Hare Intl - MSL Florence Muscle Shoals

ORDMSL

Chicago O'Hare Intl

Wed 11/11

2:55 pm-6:50 pm

2 stops27h 55m

Florence Muscle Shoals

Sun 11/15

12:25 pm-3:37 pm

2 stops27h 12m

$503

ChicagoFlorence

ORD Chicago O'Hare Intl - MSL Florence Muscle Shoals

ORDMSL

Chicago O'Hare Intl

Fri 1/1

8:59 pm-11:50 am

3 stops38h 51m

Florence Muscle Shoals

Wed 12/31

12:00 am-12:00 am

Nonstop0h 00m

$1,840

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Best time to book a flight from O'Hare Intl to Florence

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ORD-MSL

Estimated round-trip price

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Related info for your journey

What airport do you fly into for flights to Florence from Chicago O'Hare Intl?
Most people fly into Florence Muscle Shoals (MSL) if they book a flight to Florence from Chicago O'Hare Intl. On average, Muscle Shoals has 0 inbound flights from Chicago O'Hare Intl per day from 0 airlines. Florence Muscle Shoals is conveniently located just 5.4 mi from Florence’s city center.
Can I find deals for flights from O'Hare Intl to Florence that include hotel bookings?
Yes. In addition to deals on O'Hare Intl to Florence flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from O'Hare Intl to Florence?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from O'Hare Intl to Florence.
Can I find deals for business class flights from O'Hare Intl to Florence?
Yes. Cheapflights offers flight deals from O'Hare Intl to Florence by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

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$291+ Cheap flights from O'Hare Intl (ORD) to Florence, AL (MSL)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/14. Fares are subject to change and may not be available on all flights or dates of travel.

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Cheapest flights from O'Hare Intl to FlorenceExplore the most affordable flight options available from O'Hare Intl to Florence. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 30, 2026.

Explore the most affordable flight options available from O'Hare Intl to Florence. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 30, 2026.

Best flights from O'Hare Intl to FlorenceDiscover carefully curated flight deals from O'Hare Intl to Florence that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 30, 2026.

Discover carefully curated flight deals from O'Hare Intl to Florence that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 30, 2026.

Last-minute flights from O'Hare Intl to FlorenceDiscover last-minute flight deals from O'Hare Intl to Florence. Data last updated October 30, 2026 and is based on user searches.

Discover last-minute flight deals from O'Hare Intl to Florence. Data last updated October 30, 2026 and is based on user searches.

One-way flights from O'Hare Intl to FlorenceSearch for one-way flight options from O'Hare Intl to Florence. Find affordable one-way fares based on user searches. Data last updated October 30, 2026.

Search for one-way flight options from O'Hare Intl to Florence. Find affordable one-way fares based on user searches. Data last updated October 30, 2026.

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Best time to book a flight from O'Hare Intl to Florence

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Related info for your journey

What airport do you fly into for flights to Florence from Chicago O'Hare Intl?

Can I find deals for flights from O'Hare Intl to Florence that include hotel bookings?

How can I find direct flights from O'Hare Intl to Florence?

Can I find deals for business class flights from O'Hare Intl to Florence?

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Cheapest flights from O'Hare Intl to Florence
Explore the most affordable flight options available from O'Hare Intl to Florence. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 30, 2026.

Best flights from O'Hare Intl to Florence
Discover carefully curated flight deals from O'Hare Intl to Florence that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 30, 2026.

Last-minute flights from O'Hare Intl to Florence
Discover last-minute flight deals from O'Hare Intl to Florence. Data last updated October 30, 2026 and is based on user searches.

One-way flights from O'Hare Intl to Florence
Search for one-way flight options from O'Hare Intl to Florence. Find affordable one-way fares based on user searches. Data last updated October 30, 2026.