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$183+ Cheap flights from O'Hare Intl (ORD) to Florence, AL (MSL)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/31. Fares are subject to change and may not be available on all flights or dates of travel.
ORD — MSL
Jul 29 — Aug 51
Wed 7/29
Wed 8/5
1 adult, Economy
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Cheap flight deals from O'Hare Intl to Florence

One-way flights from O'Hare Intl to Florence
Search for one-way flight options from O'Hare Intl to Florence. Find affordable one-way fares based on user searches. Data last updated June 29, 2026.

This Booking.com deal was found by Cheapflights users on 6/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/3111:20 am
ORD
-
MSL
2 stops7h 50m
Contour
Deal found 6/25$183
This Kiwi.com deal was found by Cheapflights users on 6/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/281:59 pm
ORD
-
MSL
3 stops45h 51m
Multiple Airlines
Deal found 6/25$279
This Kiwi.com deal was found by Cheapflights users on 6/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/311:50 pm
ORD
-
MSL
3 stops26h 35m
Multiple Airlines
Deal found 6/25$294

Find flight deals from O'Hare Intl to Florence

Discover tips and strategies to find the most affordable flight options for your journey from O'Hare Intl (ORD) to Florence (MSL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated June 29, 2026.

Most accurate provider

Expedia
1 star

Most trusted provider

Expedia
3 stars
Provider with most accurate pricing for Chicago O'Hare Intl-Florence Muscle Shoals flight deals.
Search Deals
Provider most trusted by Cheapflights users for Chicago O'Hare Intl-Florence Muscle Shoals flights.
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from O'Hare Intl to Florence that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 29, 2026.
Use the filters below to find and compare flights from Chicago O'Hare Intl Airport to Florence that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest one-way
Quickest one-way

ChicagoFlorence

ORD - MSL

ORDMSL

Chicago O'Hare Intl

Fri 8/28

11:30 am-6:50 pm

2 stops7h 20m

$183

ChicagoFlorence

ORD - MSL

ORDMSL

Chicago O'Hare Intl

Fri 8/28

1:59 pm-11:50 am

3 stops45h 51m

$279

ChicagoFlorence

ORD - MSL

ORDMSL

Chicago O'Hare Intl

Fri 7/31

1:50 pm-4:25 pm

3 stops26h 35m

$294

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/25

Sorted by cheapest first
  • Most accurate provider: When it comes to deals on Chicago O'Hare Intl Airport-Florence, Alabama flights, users find the pricing of Expedia to be most consistent on Cheapflights vs. Expedia Users can find the same prices on Chicago O'Hare Intl Airport-Florence, Alabama flight deals on Cheapflights vs. Expedia <90% of the time. Price accuracy is based on data collected from Chicago O'Hare Intl Airport-Florence, Alabama flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Chicago O'Hare Intl Airport-Florence, Alabama flights, Cheapflights users trust Expedia the most. Expedia has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Chicago O'Hare Intl Airport-Florence, Alabama flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from O'Hare Intl to Florence

Have a flexible travel schedule? Discover the best time to fly to Florence from O'Hare Intl with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Related info for your journey

Find useful and relevant information for your journey from O'Hare Intl to Florence. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Florence from Chicago O'Hare Intl?

    Most people fly into Florence Muscle Shoals (MSL) if they book a flight to Florence from Chicago O'Hare Intl. On average, Muscle Shoals has 0 inbound flights from Chicago O'Hare Intl per day from 0 airlines. Florence Muscle Shoals is conveniently located just 5.4 mi from Florence’s city center.

  • Can I find deals for flights from O'Hare Intl to Florence that include hotel bookings?

    Yes. In addition to deals on O'Hare Intl to Florence flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from O'Hare Intl to Florence?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from O'Hare Intl to Florence.

  • Can I find deals for business class flights from O'Hare Intl to Florence?

    Yes. Cheapflights offers flight deals from O'Hare Intl to Florence by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Traveling to a place near Florence?

Book flights to Florence if you plan to visit one of these locations
Sheffield
Muscle Shoals

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