In terms of precipitation, rainfall in Florence, Alabama ranges from 2.9 - 6.1 inches per month. March is typically the wettest month, when rainfall can reach 6.1 in. October is typically the driest time to visit Florence, Alabama when rainfall is around 2.9 in.

If weather is an important factor for your trip to Florence, Alabama, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 78.8 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 41.0 F).

What is the cheapest time of day to fly from ORD to MSL?

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Chicago O'Hare Intl Airport to Florence, Alabama as you normally would.

Most accurate provider : When it comes to deals on Chicago O'Hare Intl Airport-Florence, Alabama flights, users find the pricing of Expedia to be most consistent on Cheapflights vs. Expedia Users can find the same prices on Chicago O'Hare Intl Airport-Florence, Alabama flight deals on Cheapflights vs. Expedia <90% of the time. Price accuracy is based on data collected from Chicago O'Hare Intl Airport-Florence, Alabama flight searches over the past month and is updated monthly.

Most trusted provider : When it comes to deals on Chicago O'Hare Intl Airport-Florence, Alabama flights, Cheapflights users trust Expedia the most. Expedia has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Chicago O'Hare Intl Airport-Florence, Alabama flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

What airport do you fly into for flights to Florence from Chicago O'Hare Intl?

Most people fly into Florence Muscle Shoals (MSL) if they book a flight to Florence from Chicago O'Hare Intl. On average, Muscle Shoals has 0 inbound flights from Chicago O'Hare Intl per day from 0 airlines. Florence Muscle Shoals is conveniently located just 5.4 mi from Florence’s city center.

Can I find deals for flights from O'Hare Intl to Florence that include hotel bookings?

Yes. In addition to deals on O'Hare Intl to Florence flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from O'Hare Intl to Florence?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from O'Hare Intl to Florence.

Can I find deals for business class flights from O'Hare Intl to Florence?

Yes. Cheapflights offers flight deals from O'Hare Intl to Florence by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$199+ Cheap Flights from Chicago O'Hare Intl Airport to Florence, AL

Q: E

Most trusted provider : When it comes to deals on Chicago O'Hare Intl Airport-Florence, Alabama flights, Cheapflights users trust Expedia the most. Expedia has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Chicago O'Hare Intl Airport-Florence, Alabama flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Q: What airport do you fly into for flights to Florence from Chicago O'Hare Intl?

Most people fly into Florence Muscle Shoals (MSL) if they book a flight to Florence from Chicago O'Hare Intl. On average, Muscle Shoals has 0 inbound flights from Chicago O'Hare Intl per day from 0 airlines. Florence Muscle Shoals is conveniently located just 5.4 mi from Florence’s city center.

Q: Can I find deals for flights from O'Hare Intl to Florence that include hotel bookings?

Yes. In addition to deals on O'Hare Intl to Florence flights, Cheapflights offers vacation packages that include both flights and hotel.

Q: How can I find direct flights from O'Hare Intl to Florence?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from O'Hare Intl to Florence.

Q: Can I find deals for business class flights from O'Hare Intl to Florence?

Yes. Cheapflights offers flight deals from O'Hare Intl to Florence by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

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Cheap flight deals from O'Hare Intl to Florence

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Cheapest flights from O'Hare Intl to Florence
Explore the most affordable flight options available from O'Hare Intl to Florence. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 15, 2026.

Wed 7/1511:20 am

ORD

MSL

2 stops24h 30m

Contour

Sun 7/191:00 pm

MSL

ORD

2 stops21h 40m

Contour

Deal found 7/12

$641

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Most accurate provider	Expedia 1 star
Most trusted provider	Expedia 3 stars

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ORD - MSL

ORDMSL

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Mon 8/17

11:30 am-6:50 pm

2 stops7h 20m

$199

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ORD - MSL

ORDMSL

Chicago O'Hare Intl

Wed 8/19

11:30 am-11:50 am

2 stops24h 20m

$205

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Most accurate provider: When it comes to deals on Chicago O'Hare Intl Airport-Florence, Alabama flights, users find the pricing of Expedia to be most consistent on Cheapflights vs. Expedia Users can find the same prices on Chicago O'Hare Intl Airport-Florence, Alabama flight deals on Cheapflights vs. Expedia <90% of the time. Price accuracy is based on data collected from Chicago O'Hare Intl Airport-Florence, Alabama flight searches over the past month and is updated monthly.
Most trusted provider: When it comes to deals on Chicago O'Hare Intl Airport-Florence, Alabama flights, Cheapflights users trust Expedia the most. Expedia has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Chicago O'Hare Intl Airport-Florence, Alabama flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from O'Hare Intl to Florence

Have a flexible travel schedule? Discover the best time to fly to Florence from O'Hare Intl with our price prediction graph.

ORD-MSL

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Related info for your journey

What airport do you fly into for flights to Florence from Chicago O'Hare Intl?
Most people fly into Florence Muscle Shoals (MSL) if they book a flight to Florence from Chicago O'Hare Intl. On average, Muscle Shoals has 0 inbound flights from Chicago O'Hare Intl per day from 0 airlines. Florence Muscle Shoals is conveniently located just 5.4 mi from Florence’s city center.
Can I find deals for flights from O'Hare Intl to Florence that include hotel bookings?
Yes. In addition to deals on O'Hare Intl to Florence flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from O'Hare Intl to Florence?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from O'Hare Intl to Florence.
Can I find deals for business class flights from O'Hare Intl to Florence?
Yes. Cheapflights offers flight deals from O'Hare Intl to Florence by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

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$199+ Cheap flights from O'Hare Intl (ORD) to Florence, AL (MSL)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/17. Fares are subject to change and may not be available on all flights or dates of travel.

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Cheapest flights from O'Hare Intl to FlorenceExplore the most affordable flight options available from O'Hare Intl to Florence. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 15, 2026.

Explore the most affordable flight options available from O'Hare Intl to Florence. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 15, 2026.

Last-minute flights from O'Hare Intl to FlorenceDiscover last-minute flight deals from O'Hare Intl to Florence. Data last updated July 15, 2026 and is based on user searches.

Discover last-minute flight deals from O'Hare Intl to Florence. Data last updated July 15, 2026 and is based on user searches.

One-way flights from O'Hare Intl to FlorenceSearch for one-way flight options from O'Hare Intl to Florence. Find affordable one-way fares based on user searches. Data last updated July 15, 2026.

Search for one-way flight options from O'Hare Intl to Florence. Find affordable one-way fares based on user searches. Data last updated July 15, 2026.

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Use the filters below to find and compare flights from Chicago O'Hare Intl Airport to Florence that are best for you.

Best time to book a flight from O'Hare Intl to Florence

Have a flexible travel schedule? Discover the best time to fly to Florence from O'Hare Intl with our price prediction graph.

Related info for your journey

What airport do you fly into for flights to Florence from Chicago O'Hare Intl?

Can I find deals for flights from O'Hare Intl to Florence that include hotel bookings?

How can I find direct flights from O'Hare Intl to Florence?

Can I find deals for business class flights from O'Hare Intl to Florence?

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Cheapest flights from O'Hare Intl to Florence
Explore the most affordable flight options available from O'Hare Intl to Florence. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 15, 2026.

Last-minute flights from O'Hare Intl to Florence
Discover last-minute flight deals from O'Hare Intl to Florence. Data last updated July 15, 2026 and is based on user searches.

One-way flights from O'Hare Intl to Florence
Search for one-way flight options from O'Hare Intl to Florence. Find affordable one-way fares based on user searches. Data last updated July 15, 2026.