$393+ Cheap flights from O'Hare Intl (ORD) to Florence, AL (MSL)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/24. Fares are subject to change and may not be available on all flights or dates of travel.
ORD — MSL
Oct 15 — Oct 221
Round-trip
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from O'Hare Intl to Florence with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from O'Hare Intl to Florence
Cheapest
Last-minute
Cheapest flights from O'Hare Intl to FlorenceExplore the most affordable flight options available from O'Hare Intl to Florence. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 15, 2026.
Explore the most affordable flight options available from O'Hare Intl to Florence. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 15, 2026.
This Booking.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/2411:30 am -
2 stops7h 20m
Mon 9/2812:45 pm -
2 stops22h 05m
Deal found 9/10![Contour logo]()
$393
This KAYAK deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/243:00 pm -
2 stops27h 50m
Mon 9/287:10 am -
2 stops27h 40m
Deal found 9/10![Multiple Airlines logo]()
$818
Last-minute flights from O'Hare Intl to FlorenceDiscover last-minute flight deals from O'Hare Intl to Florence. Data last updated September 15, 2026 and is based on user searches.
Discover last-minute flight deals from O'Hare Intl to Florence. Data last updated September 15, 2026 and is based on user searches.
This Booking.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/2411:30 am -
2 stops7h 20m
Mon 9/2812:45 pm -
2 stops22h 05m
Deal found 9/10![Contour logo]()
$393
This KAYAK deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/243:00 pm -
2 stops27h 50m
Mon 9/287:10 am -
2 stops27h 40m
Deal found 9/10![Multiple Airlines logo]()
$818
Find flight deals from O'Hare Intl to Florence
Discover tips and strategies to find the most affordable flight options for your journey from O'Hare Intl (ORD) to Florence (MSL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 15, 2026.
Round-trip from | $393 (Booking.com) |
|---|
Best time to book a flight from O'Hare Intl to Florence
Have a flexible travel schedule? Discover the best time to fly to Florence from O'Hare Intl with our price prediction graph.
ORD-MSL
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Related info for your journey
Find useful and relevant information for your journey from O'Hare Intl to Florence. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Florence?
Book flights to Florence if you plan to visit one of these locationsSheffield
Muscle Shoals
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Complete your trip
Flights by cabin class
Florence flight routes
Other flight options
Other flights from O'Hare Intl
Popular flights