In terms of precipitation, rainfall in Florence, Alabama ranges from 2.9 - 6.1 inches per month. March is typically the wettest month, when rainfall can reach 6.1 in. October is typically the driest time to visit Florence, Alabama when rainfall is around 2.9 in.

If weather is an important factor for your trip to Florence, Alabama, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 78.8 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 41.0 F).

What is the cheapest time of day to fly from ORD to MSL?

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Chicago O'Hare Intl Airport to Florence, Alabama as you normally would.

What airport do you fly into for flights to Florence from Chicago O'Hare Intl?

Most people fly into Florence Muscle Shoals (MSL) if they book a flight to Florence from Chicago O'Hare Intl. On average, Muscle Shoals has 0 inbound flights from Chicago O'Hare Intl per day from 0 airlines. Florence Muscle Shoals is conveniently located just 5.4 mi from Florence’s city center.

Can I find deals for flights from O'Hare Intl to Florence that include hotel bookings?

Yes. In addition to deals on O'Hare Intl to Florence flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from O'Hare Intl to Florence?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from O'Hare Intl to Florence.

Can I find deals for business class flights from O'Hare Intl to Florence?

Yes. Cheapflights offers flight deals from O'Hare Intl to Florence by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$552+ Cheap Flights from Chicago O'Hare Intl Airport to Florence, AL

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Cheapest flights from O'Hare Intl to Florence
Explore the most affordable flight options available from O'Hare Intl to Florence. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 27, 2026.

Mon 11/96:30 am -

2 stops11h 40m

Fri 11/137:50 am -

2 stops30h 25m

Deal found 10/25

$552

Thu 12/173:57 pm -

1 stop26h 53m

Sun 12/2712:25 pm -

2 stops36h 43m

Deal found 10/23

$604

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Round-trip from	$552 (Mytrip)

From Chicago O'Hare Intl to Florence Muscle Shoals

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ORD Chicago O'Hare Intl - MSL Florence Muscle Shoals

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Mon 11/9

6:30 am-6:10 pm

2 stops11h 40m

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Fri 11/13

7:50 am-2:15 pm

2 stops30h 25m

$552

ChicagoFlorence

ORD Chicago O'Hare Intl - MSL Florence Muscle Shoals

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Chicago O'Hare Intl

Thu 12/17

3:57 pm-6:50 pm

1 stop26h 53m

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Sun 12/27

12:25 pm-1:08 am

2 stops36h 43m

$604

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Related info for your journey

What airport do you fly into for flights to Florence from Chicago O'Hare Intl?
Most people fly into Florence Muscle Shoals (MSL) if they book a flight to Florence from Chicago O'Hare Intl. On average, Muscle Shoals has 0 inbound flights from Chicago O'Hare Intl per day from 0 airlines. Florence Muscle Shoals is conveniently located just 5.4 mi from Florence’s city center.
Can I find deals for flights from O'Hare Intl to Florence that include hotel bookings?
Yes. In addition to deals on O'Hare Intl to Florence flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from O'Hare Intl to Florence?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from O'Hare Intl to Florence.
Can I find deals for business class flights from O'Hare Intl to Florence?
Yes. Cheapflights offers flight deals from O'Hare Intl to Florence by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

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$552+ Cheap flights from O'Hare Intl (ORD) to Florence, AL (MSL)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/9. Fares are subject to change and may not be available on all flights or dates of travel.

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Cheapest flights from O'Hare Intl to FlorenceExplore the most affordable flight options available from O'Hare Intl to Florence. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 27, 2026.

Explore the most affordable flight options available from O'Hare Intl to Florence. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 27, 2026.

Best flights from O'Hare Intl to FlorenceDiscover carefully curated flight deals from O'Hare Intl to Florence that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 27, 2026.

Discover carefully curated flight deals from O'Hare Intl to Florence that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 27, 2026.

Last-minute flights from O'Hare Intl to FlorenceDiscover last-minute flight deals from O'Hare Intl to Florence. Data last updated October 27, 2026 and is based on user searches.

Discover last-minute flight deals from O'Hare Intl to Florence. Data last updated October 27, 2026 and is based on user searches.

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Best time to book a flight from O'Hare Intl to Florence

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Related info for your journey

What airport do you fly into for flights to Florence from Chicago O'Hare Intl?

Can I find deals for flights from O'Hare Intl to Florence that include hotel bookings?

How can I find direct flights from O'Hare Intl to Florence?

Can I find deals for business class flights from O'Hare Intl to Florence?

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Cheapest flights from O'Hare Intl to Florence
Explore the most affordable flight options available from O'Hare Intl to Florence. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 27, 2026.

Best flights from O'Hare Intl to Florence
Discover carefully curated flight deals from O'Hare Intl to Florence that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 27, 2026.

Last-minute flights from O'Hare Intl to Florence
Discover last-minute flight deals from O'Hare Intl to Florence. Data last updated October 27, 2026 and is based on user searches.