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$239+ Cheap flights from Roanoke (ROA) to Missouri

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/15. Fares are subject to change and may not be available on all flights or dates of travel.
ROA — MCI
Jan 17 — Jan 241
Sat 1/17
Sat 1/24
1 adult, Economy
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Cheap flight deals from Roanoke to Missouri

Cheapest flights from Roanoke to Missouri
Explore the most affordable flight options available from Roanoke to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 18, 2025.

This American Airlines deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/277:07 pmROA - STL
1 stop5h 49mAmerican Airlines
Sat 1/35:00 amSTL - ROA
1 stop4h 31mAmerican Airlines
Deal found 12/16$309
This American Airlines deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/267:08 amROA - STL
1 stop7h 28mAmerican Airlines
Mon 12/295:00 amSTL - ROA
1 stop4h 31mAmerican Airlines
Deal found 12/16$339
This American Airlines deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/198:14 amROA - STL
1 stop5h 15mAmerican Airlines
Fri 12/265:00 amSTL - ROA
1 stop4h 31mAmerican Airlines
Deal found 12/16$354
This American Airlines deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/195:00 amROA - STL
1 stop4h 35mAmerican Airlines
Sat 12/205:16 pmSTL - ROA
1 stop5h 23mAmerican Airlines
Deal found 12/16$369
This United Airlines deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/195:42 pmROA - STL
1 stop6h 01mUnited Airlines
Sat 12/203:10 pmSTL - ROA
1 stop4h 48mUnited Airlines
Deal found 12/17$509
This Delta deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/178:00 pmROA - MCI
1 stop4h 47mDelta
Sat 1/104:01 pmMCI - ROA
1 stop7h 03mDelta
Deal found 12/16$579
This United Airlines deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/272:55 pmROA - STL
1 stop5h 27mUnited Airlines
Sat 1/311:05 amSTL - ROA
2 stops11h 25mUnited Airlines
Deal found 12/16$592
This United Airlines deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/262:55 pmROA - STL
1 stop5h 27mUnited Airlines
Mon 12/296:35 pmSTL - ROA
2 stops14h 22mUnited Airlines
Deal found 12/16$684
This United Airlines deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/1910:52 amROA - STL
1 stop4h 34mUnited Airlines
Fri 12/2610:30 amSTL - ROA
2 stops12h 00mUnited Airlines
Deal found 12/16$789
This American Airlines deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/178:12 amROA - MCI
2 stops8h 50mAmerican Airlines
Sat 1/105:48 amMCI - ROA
2 stops8h 17mAmerican Airlines
Deal found 12/16$915
This United Airlines deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/1710:20 amROA - MCI
1 stop5h 39mUnited Airlines
Sat 1/106:30 pmMCI - ROA
1 stop16h 35mUnited Airlines
Deal found 12/16$1,040

Find flight deals from Roanoke to Missouri

Keep the following information in mind while searching for Roanoke to Missouri flight deals. Data was last updated December 18, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$239
(Delta)

Popular in

May

Cheapest in

August

Average price

$308
Provider with most accurate pricing for Roanoke-Lambert-St Louis flight deals.
Search Deals
Provider most trusted by Cheapflights users for Roanoke-Lambert-St Louis flights.
Search Deals
From Roanoke to Missouri
Search Deals
Highest demand for flights based on searches. 11% potential increase in price ($44 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($10 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Roanoke to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 18, 2025.
Use the filters below to find and compare flights from Roanoke to Missouri that are best for you.

Fly from

Roanoke

Fly to

Missouri

Route

Depart

Return

Price

RoanokeSt. Louis

ROA - STL

ROASTL

Roanoke

Sat 1/17

6:00 am-11:02 am

1 stop6h 02m

Lambert-St Louis

Sat 1/24

7:10 am-3:07 pm

1 stop6h 57m

$239

RoanokeSt. Louis

ROA - STL

ROASTL

Roanoke

Thu 1/15

6:00 am-11:05 am

1 stop6h 05m

Lambert-St Louis

Mon 2/2

6:57 pm-12:04 am

1 stop4h 07m

$239

RoanokeSt. Louis

ROA - STL

ROASTL

Roanoke

Thu 1/15

6:00 am-11:05 am

1 stop6h 05m

Lambert-St Louis

Wed 2/4

7:10 am-3:09 pm

1 stop6h 59m

$239

RoanokeSt. Louis

ROA - STL

ROASTL

Roanoke

Thu 1/15

7:05 am-12:33 pm

1 stop6h 28m

Lambert-St Louis

Fri 2/6

6:57 pm-12:04 am

1 stop4h 07m

$239

RoanokeKansas City

ROA - MCI

ROAMCI

Roanoke

Sat 5/30

6:00 am-11:27 am

1 stop6h 27m

Kansas City

Sat 6/6

5:00 pm-11:49 pm

1 stop5h 49m

$269

RoanokeKansas City

ROA - MCI

ROAMCI

Roanoke

Sat 2/7

3:49 pm-9:37 pm

1 stop6h 48m

Kansas City

Wed 2/11

7:00 am-3:09 pm

1 stop7h 09m

$269

RoanokeKansas City

ROA - MCI

ROAMCI

Roanoke

Fri 2/6

3:49 pm-10:02 pm

1 stop7h 13m

Kansas City

Wed 2/11

7:00 am-3:09 pm

1 stop7h 09m

$269

RoanokeKansas City

ROA - MCI

ROAMCI

Roanoke

Fri 2/6

3:49 pm-8:02 pm

1 stop5h 13m

Kansas City

Tue 2/10

1:22 pm-7:19 pm

1 stop4h 57m

$269

RoanokeKansas City

ROA - MCI

ROAMCI

Roanoke

Fri 2/6

3:49 pm-8:02 pm

1 stop5h 13m

Kansas City

Fri 2/13

6:13 pm-11:49 pm

1 stop4h 36m

$269

RoanokeKansas City

ROA - MCI

ROAMCI

Roanoke

Tue 2/24

3:27 pm-8:41 pm

1 stop6h 14m

Kansas City

Wed 3/4

8:05 am-2:45 pm

1 stop5h 40m

$269

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/17

Showing 1-10 of 27 results
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Best time to book a flight from Roanoke to Missouri

Have a flexible travel schedule? Discover the best time to fly to Missouri from Roanoke with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Roanoke to Missouri

What is the cheapest month to book a flight from Roanoke to Missouri?

Currently, November is the cheapest month in which you can book a flight from Roanoke to Missouri (average of $183). Flying from Roanoke to Missouri in July is currently the most expensive (average of $248). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from ROA to MO?

Find hourly flight availability from Roanoke to Missouri. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 18, 2025.

Unlike in the afternoon, when flights are generally more expensive, you can save up to 41% on flights from Roanoke to Missouri by exploring options for tickets in the evening.

What is the cheapest day to fly from Roanoke to Missouri?

Use this chart to determine the cheapest time to fly round-trip from Roanoke to Missouri. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their Roanoke to Missouri flight should consider departing on Tuesday evenings when fares are most often at their lowest. Sunday at noon flights should be avoided if possible as fares are typically the most expensive at this time.

Reviews of airlines servicing Missouri

Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated December 18, 2025.
Read reviews from past customers who have flown Delta, United Airlines, and American Airlines from Roanoke to Missouri. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,005 reviews

Entertainment

7.9

Food

7.3

Boarding

8.1

Comfort

7.9

Crew

8.5

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,005 reviews
Delta
7.9
Good
8,005 reviews

Entertainment

7.9

Food

7.3

Boarding

8.1

Comfort

7.9

Crew

8.5

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
United Airlines
7.4
Good
9,091 reviews
Delta
7.9
Good
8,005 reviews

Entertainment

7.9

Food

7.3

Boarding

8.1

Comfort

7.9

Crew

8.5

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.2
Good
11,054 reviews
Delta
7.9
Good
8,005 reviews

Entertainment

7.9

Food

7.3

Boarding

8.1

Comfort

7.9

Crew

8.5

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Roanoke to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Roanoke to Missouri?

    For a flight from Roanoke to Missouri, you will be flying from Roanoke. Roanoke (ROA) is just 4.2 mi from the center of the city.

  • How long is the flight from Roanoke to Missouri?

    Delta and United Airlines can get you from Roanoke to Missouri in just under 6h 02m. Your travel time can differ by up to 1h 17m. Airlines will cover a distance of 574 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the most popular routes from Roanoke to Missouri?

    The most popular route from Roanoke to Missouri is Roanoke - Lambert-St Louis. You may also consider Roanoke - Kansas City or Roanoke - Springfield-Branson.

  • Can I find deals for flights from Roanoke to Missouri that include hotel bookings?

    Yes. In addition to deals on Roanoke to Missouri flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Roanoke to Missouri?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Roanoke to Missouri.

  • Can I find deals for business class flights from Roanoke to Missouri?

    Yes. Cheapflights offers flight deals from Roanoke to Missouri by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Roanoke to Missouri?

    Currently, November is the cheapest month in which you can book a flight from Roanoke to Missouri (average of $183). Flying from Roanoke to Missouri in July is currently the most expensive (average of $248). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top 3 airlines flying from Roanoke to Missouri

Discover the top 3 airlines that operate flights from Roanoke to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 18, 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$248Average$354FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$248Average$391FlexibilityNo cancel feeOn-time71%
DeltaCheapest$248Average$378FlexibilityNo cancel feeOn-timeN/A

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