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$211+ Cheap flights from Roanoke (ROA) to Missouri

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/28. Fares are subject to change and may not be available on all flights or dates of travel.
ROA — STL
Aug 4 — Aug 111
Mon 8/4
Mon 8/11
1 adult, Economy
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Cheap flight deals from Roanoke to Missouri

Keep the following information in mind while searching for Roanoke to Missouri flight deals. Data was last updated July 30, 2025.

Round-trip from

$249
(Delta)

One-way from

$211
(Delta)

Popular in

March

Cheapest in

July

Average price

$293
From Roanoke to Missouri
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One-way flight from Roanoke to Missouri
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Highest demand for flights based on searches. 18% potential increase in price ($90 potential increase over avg. RT price).
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Cheapest flight prices on average. 8% potential price decrease ($35 potential savings vs. average RT price).
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Average for round-trip flights in July 2025
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Find flight deals from Roanoke to Missouri

Cheapest flights from Roanoke to Missouri
Explore the most affordable flight options available from Roanoke to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 30, 2025.

This Delta deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/197:51 pmROA - MCI
1 stop4h 53mDelta
Mon 9/296:42 pmMCI - ROA
1 stop4h 43mDelta
Deal found 7/28$249
This Delta deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/63:32 pmROA - STL
1 stop4h 35mDelta
Fri 9/126:42 pmSTL - ROA
1 stop4h 43mDelta
Deal found 7/29$249
This United Airlines deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/256:45 amROA - MCI
1 stop4h 52mUnited Airlines
Tue 10/283:25 pmMCI - ROA
2 stops7h 05mUnited Airlines
Deal found 7/29$295
This American Airlines deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/246:00 amROA - MCI
1 stop7h 54mAmerican Airlines
Sat 11/19:41 amMCI - ROA
2 stops9h 12mAmerican Airlines
Deal found 7/30$298
This American Airlines deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/76:10 pmROA - STL
1 stop6h 43mAmerican Airlines
Sat 9/136:00 amSTL - ROA
1 stop7h 36mAmerican Airlines
Deal found 7/29$319
This United Airlines deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/66:20 amROA - STL
2 stops10h 24mUnited Airlines
Fri 9/123:20 pmSTL - ROA
1 stop4h 59mUnited Airlines
Deal found 7/29$374

Cheapflights Fare Finder

 
Customize your flight search to find flights from Roanoke to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 30, 2025.
Use the filters below to find and compare flights from Roanoke to Missouri that are best for you.

Fly from

Roanoke

Fly to

Missouri

Route

Depart

Return

Price

RoanokeKansas City

ROA - MCI

ROAMCI

Roanoke

Fri 9/19

7:51 pm-11:44 pm

1 stop4h 53m

Kansas City

Mon 9/29

6:42 pm-12:25 am

1 stop4h 43m

$249

RoanokeSt. Louis

ROA - STL

ROASTL

Roanoke

Sat 9/6

3:32 pm-7:07 pm

1 stop4h 35m

Lambert-St Louis

Fri 9/12

6:42 pm-12:25 am

1 stop4h 43m

$249

RoanokeKansas City

ROA - MCI

ROAMCI

Roanoke

Sat 10/25

6:45 am-10:37 am

1 stop4h 52m

Kansas City

Tue 10/28

3:25 pm-11:30 pm

2 stops7h 05m

$295

RoanokeKansas City

ROA - MCI

ROAMCI

Roanoke

Fri 10/24

6:00 am-12:54 pm

1 stop7h 54m

Kansas City

Sat 11/1

9:41 am-7:53 pm

2 stops9h 12m

$298

RoanokeSt. Louis

ROA - STL

ROASTL

Roanoke

Sun 9/7

6:10 pm-11:53 pm

1 stop6h 43m

Lambert-St Louis

Sat 9/13

6:00 am-2:36 pm

1 stop7h 36m

$319

RoanokeSt. Louis

ROA - STL

ROASTL

Roanoke

Sat 9/6

6:20 am-3:44 pm

2 stops10h 24m

Lambert-St Louis

Fri 9/12

3:20 pm-9:19 pm

1 stop4h 59m

$374

RoanokeKansas City

ROA - MCI

ROAMCI

Roanoke

Sun 9/28

7:51 pm-11:44 pm

1 stop4h 53m

$211

RoanokeKansas City

ROA - MCI

ROAMCI

Roanoke

Mon 9/1

6:20 am-2:13 pm

2 stops8h 53m

$251

RoanokeSt. Louis

ROA - STL

ROASTL

Roanoke

Mon 8/4

8:11 pm-11:53 pm

1 stop4h 42m

$254

RoanokeSt. Louis

ROA - STL

ROASTL

Roanoke

Fri 11/7

5:38 pm-9:40 pm

1 stop5h 02m

$369

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/29

Best time to book a flight from Roanoke to Missouri

Have a flexible travel schedule? Discover the best time to fly to Missouri from Roanoke with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Roanoke to Missouri

What is the cheapest month to book a flight from Roanoke to Missouri?

Currently, August is the cheapest month in which you can book a flight from Roanoke to Missouri (average of $311). Flying from Roanoke to Missouri in March is currently the most expensive (average of $356). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from ROA to MO?

Find hourly flight availability from Roanoke to Missouri. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated July 30, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Roanoke to Missouri as you normally would.

Reviews of airlines servicing Missouri

Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated July 30, 2025.
Read reviews from past customers who have flown Delta, United Airlines, and American Airlines from Roanoke to Missouri. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,980 reviews

Food

7.3

Comfort

7.9

Entertainment

7.9

Boarding

8.2

Crew

8.5

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Delta
8.0
Very good
7,980 reviews
Delta
8.0
Very good
7,980 reviews

Food

7.3

Comfort

7.9

Entertainment

7.9

Boarding

8.2

Crew

8.5

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
United Airlines
7.4
Good
8,896 reviews
Delta
8.0
Very good
7,980 reviews

Food

7.3

Comfort

7.9

Entertainment

7.9

Boarding

8.2

Crew

8.5

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,980 reviews

Food

7.3

Comfort

7.9

Entertainment

7.9

Boarding

8.2

Crew

8.5

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

Find useful and relevant information for your journey from Roanoke to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Roanoke to Missouri?

    For a flight from Roanoke to Missouri, you will be flying from Roanoke. Roanoke (ROA) is just 4.2 mi from the center of the city.

  • What are the most popular routes from Roanoke to Missouri?

    The most popular route from Roanoke to Missouri is Roanoke - Lambert-St Louis. You may also consider Roanoke - Kansas City or Roanoke - Springfield-Branson.

  • Can I find deals for flights from Roanoke to Missouri that include hotel bookings?

    Yes. In addition to deals on Roanoke to Missouri flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Roanoke to Missouri?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Roanoke to Missouri.

  • Can I find deals for business class flights from Roanoke to Missouri?

    Yes. Cheapflights offers flight deals from Roanoke to Missouri by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Roanoke to Missouri?

    Currently, August is the cheapest month in which you can book a flight from Roanoke to Missouri (average of $311). Flying from Roanoke to Missouri in March is currently the most expensive (average of $356). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top 3 airlines flying from Roanoke to Missouri

Discover the top 3 airlines that operate flights from Roanoke to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 30, 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$218Average$406FlexibilityNo cancel feeOn-time69%
DeltaCheapest$242Average$359FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$248Average$388FlexibilityNo cancel feeOn-time71%

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