$52+ Cheap flights from Pennsylvania to Missouri
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/22. Fares are subject to change and may not be available on all flights or dates of travel.
PHL — STL
Aug 22 — Aug 291
Round-trip
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from Pennsylvania to Missouri with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Pennsylvania to Missouri
Cheapest
Best
Last-minute
One-way
Cheapest flights from Pennsylvania to MissouriExplore the most affordable flight options available from Pennsylvania to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 23, 2026.
Explore the most affordable flight options available from Pennsylvania to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 23, 2026.
This Kiwi.com deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/84:45 pm
PHL
- STL
1 stop17h 55m
Frontier
Sat 9/1210:35 am
STL
- PHL
1 stop6h 40m
Frontier
Deal found 7/23![Frontier logo]()
$99
This Kiwi.com deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/2212:43 pm
PHL
- STL
1 stop21h 57m
Frontier
Sat 9/2610:35 am
STL
- PHL
1 stop6h 40m
Frontier
Deal found 7/22![Frontier logo]()
$101
This Kiwi.com deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/2212:43 pm
PHL
- STL
1 stop21h 57m
Frontier
Tue 9/2910:35 am
STL
- PHL
1 stop6h 40m
Frontier
Deal found 7/22![Frontier logo]()
$102
This Kiwi.com deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/115:28 pm
PHL
- STL
1 stop17h 12m
Frontier
Tue 9/1510:35 am
STL
- PHL
1 stop6h 40m
Frontier
Deal found 7/22![Frontier logo]()
$105
This Kiwi.com deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/225:28 pm
PHL
- STL
1 stop17h 12m
Frontier
Fri 9/2510:35 am
STL
- PHL
1 stop20h 01m
Frontier
Deal found 7/22![Frontier logo]()
$106
This Kiwi.com deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/235:28 pm
PHL
- STL
1 stop17h 12m
Frontier
Tue 9/2910:35 am
STL
- PHL
1 stop6h 40m
Frontier
Deal found 7/22![Frontier logo]()
$107
This Kiwi.com deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/2512:43 pm
PHL
- STL
1 stop21h 57m
Frontier
Tue 9/2910:35 am
STL
- PHL
1 stop11h 36m
Frontier
Deal found 7/22![Frontier logo]()
$108
This Kiwi.com deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/45:28 pm
PHL
- STL
1 stop17h 12m
Frontier
Wed 10/710:35 am
STL
- PHL
1 stop6h 40m
Frontier
Deal found 7/22![Frontier logo]()
$111
This Kiwi.com deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/225:28 pm
PHL
- STL
1 stop17h 12m
Frontier
Thu 10/110:35 am
STL
- PHL
1 stop6h 40m
Frontier
Deal found 7/22![Frontier logo]()
$112
This Kiwi.com deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/235:28 pm
PHL
- STL
1 stop17h 12m
Frontier
Mon 9/2810:35 am
STL
- PHL
1 stop20h 01m
Frontier
Deal found 7/22![Frontier logo]()
$113
This Kiwi.com deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/136:25 am
PHL
- STL
1 stop12h 12m
Frontier
Mon 8/174:57 pm
STL
- PHL
1 stop18h 29m
Frontier
Deal found 7/22![Frontier logo]()
$117
This Kiwi.com deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/116:25 am
PHL
- STL
1 stop27h 32m
Frontier
Thu 8/136:34 pm
STL
- PHL
1 stop11h 41m
Frontier
Deal found 7/22![Frontier logo]()
$118
Best flights from Pennsylvania to MissouriDiscover carefully curated flight deals from Pennsylvania to Missouri that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 23, 2026.
Discover carefully curated flight deals from Pennsylvania to Missouri that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 23, 2026.
This Delta deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/155:47 pm
IAD
- STL
1 stop6h 44m
Delta
Mon 8/1712:52 pm
STL
- IAD
1 stop4h 36m
Delta
Deal found 7/22![Delta logo]()
$257
This United Airlines deal was found by Cheapflights users on 7/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/185:15 pm
IAD
- STL
1 stop5h 45m
United Airlines
Tue 8/257:25 am
STL
- IAD
1 stop5h 30m
United Airlines
Deal found 7/20![United Airlines logo]()
$257
This Southwest deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/177:25 am
DCA
- STL
1 stop4h 05m
Southwest
Wed 8/193:05 pm
STL
- DCA
1 stop6h 00m
Southwest
Deal found 7/22![Southwest logo]()
$257
This Southwest deal was found by Cheapflights users on 7/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/83:25 pm
DCA
- STL
Nonstop2h 30m
Southwest
Sat 10/103:00 pm
STL
- DCA
Nonstop2h 00m
Southwest
Deal found 7/18![Southwest logo]()
$269
This Delta deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/306:00 am
IAD
- MCI
1 stop6h 15m
Delta
Mon 10/52:26 pm
MCI
- IAD
1 stop6h 18m
Delta
Deal found 7/22![Delta logo]()
$281
This United Airlines deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/155:45 pm
IAD
- STL
Nonstop2h 26m
United Airlines
Mon 8/171:00 pm
STL
- IAD
Nonstop2h 06m
United Airlines
Deal found 7/22![United Airlines logo]()
$291
This Alaska Airlines deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/299:30 am
JFK
- MCI
2 stops15h 29m
Alaska Airlines
Tue 11/37:01 am
MCI
- JFK
2 stops22h 35m
Alaska Airlines
Deal found 7/22![Alaska Airlines logo]()
$584
This Southwest deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/122:45 pm
PHL
- STL
Nonstop2h 20m
Southwest
Thu 8/137:05 pm
STL
- PHL
Nonstop2h 10m
Southwest
Deal found 7/21![Southwest logo]()
$277
This Delta deal was found by Cheapflights users on 7/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/55:16 pm
PHL
- STL
1 stop7h 15m
Delta
Sun 9/61:04 pm
STL
- PHL
1 stop5h 54m
Delta
Deal found 7/18![Delta logo]()
$297
This United Airlines deal was found by Cheapflights users on 7/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/296:15 am
IAD
- MCI
1 stop5h 10m
United Airlines
Mon 8/315:39 pm
MCI
- IAD
Nonstop2h 39m
United Airlines
Deal found 7/19![United Airlines logo]()
$305
This Southwest deal was found by Cheapflights users on 7/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/106:55 am
DCA
- STL
1 stop4h 15m
Southwest
Mon 8/177:55 pm
STL
- DCA
Nonstop2h 00m
Southwest
Deal found 7/20![Southwest logo]()
$279
This United Airlines deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/1810:35 am
IAD
- STL
1 stop6h 03m
United Airlines
Fri 8/218:00 am
STL
- IAD
1 stop4h 55m
United Airlines
Deal found 7/21![United Airlines logo]()
$307
This Southwest deal was found by Cheapflights users on 7/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/278:15 am
DCA
- STL
Nonstop2h 20m
Southwest
Sat 8/295:05 am
STL
- DCA
2 stops7h 50m
Southwest
Deal found 7/19![Southwest logo]()
$284
This Delta deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/108:35 am
JFK
- STL
1 stop4h 57m
Delta
Sat 9/123:54 pm
STL
- JFK
1 stop5h 08m
Delta
Deal found 7/22![Delta logo]()
$313
This United Airlines deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/128:05 am
LGA
- STL
1 stop4h 57m
United Airlines
Thu 8/209:30 am
STL
- LGA
1 stop5h 49m
United Airlines
Deal found 7/21![United Airlines logo]()
$313
This Southwest deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/77:00 am
PHL
- STL
1 stop5h 45m
Southwest
Sat 10/104:55 pm
STL
- PHL
Nonstop2h 05m
Southwest
Deal found 7/22![Southwest logo]()
$287
This Delta deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/156:00 am
IAD
- MCI
1 stop4h 49m
Delta
Mon 10/196:42 pm
MCI
- IAD
1 stop4h 49m
Delta
Deal found 7/21![Delta logo]()
$325
This Southwest deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/105:55 am
PHL
- STL
1 stop4h 20m
Southwest
Mon 10/127:50 pm
STL
- PHL
Nonstop2h 20m
Southwest
Deal found 7/21![Southwest logo]()
$287
This United Airlines deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/319:44 pm
EWR
- MCI
Nonstop3h 15m
United Airlines
Wed 9/26:07 am
MCI
- EWR
Nonstop2h 52m
United Airlines
Deal found 7/22![United Airlines logo]()
$323
This Delta deal was found by Cheapflights users on 7/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/53:40 pm
JFK
- STL
1 stop5h 53m
Delta
Sat 9/123:54 pm
STL
- JFK
1 stop5h 08m
Delta
Deal found 7/18![Delta logo]()
$327
This Southwest deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/283:30 pm
DCA
- STL
Nonstop2h 15m
Southwest
Mon 8/318:10 am
STL
- DCA
Nonstop2h 00m
Southwest
Deal found 7/22![Southwest logo]()
$292
This United Airlines deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/128:25 am
IAD
- STL
Nonstop2h 14m
United Airlines
Thu 8/138:40 am
STL
- IAD
Nonstop2h 14m
United Airlines
Deal found 7/21![United Airlines logo]()
$324
This Delta deal was found by Cheapflights users on 7/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/227:00 pm
JFK
- STL
1 stop5h 31m
Delta
Tue 8/252:10 pm
STL
- JFK
1 stop4h 59m
Delta
Deal found 7/20![Delta logo]()
$341
This United Airlines deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/236:15 am
IAD
- STL
1 stop6h 47m
United Airlines
Thu 8/278:40 am
STL
- IAD
Nonstop2h 14m
United Airlines
Deal found 7/22![United Airlines logo]()
$324
This Southwest deal was found by Cheapflights users on 7/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/52:10 pm
PHL
- STL
1 stop8h 25m
Southwest
Sun 9/610:30 am
STL
- PHL
2 stops9h 50m
Southwest
Deal found 7/18![Southwest logo]()
$302
This Alaska Airlines deal was found by Cheapflights users on 7/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/195:20 pm
JFK
- MCI
1 stop24h 58m
Alaska Airlines
Sat 10/246:14 pm
MCI
- JFK
2 stops27h 45m
Alaska Airlines
Deal found 7/19![Alaska Airlines logo]()
$603
This Delta deal was found by Cheapflights users on 7/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/312:18 pm
IAD
- STL
1 stop3h 56m
Delta
Sun 10/46:54 pm
STL
- IAD
1 stop4h 47m
Delta
Deal found 7/19![Delta logo]()
$345
This Southwest deal was found by Cheapflights users on 7/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/28:00 am
DCA
- STL
Nonstop2h 25m
Southwest
Sat 10/35:45 pm
STL
- DCA
Nonstop2h 00m
Southwest
Deal found 7/19![Southwest logo]()
$303
This United Airlines deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/125:44 pm
IAD
- MCI
Nonstop2h 48m
United Airlines
Sat 8/155:39 pm
MCI
- IAD
Nonstop2h 39m
United Airlines
Deal found 7/22![United Airlines logo]()
$341
This Delta deal was found by Cheapflights users on 7/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/1712:15 pm
IAD
- STL
1 stop4h 10m
Delta
Sun 10/1810:02 am
STL
- IAD
1 stop4h 47m
Delta
Deal found 7/18![Delta logo]()
$345
Last-minute flights from Pennsylvania to MissouriDiscover last-minute flight deals from Pennsylvania to Missouri. Data last updated July 23, 2026 and is based on user searches.
Discover last-minute flight deals from Pennsylvania to Missouri. Data last updated July 23, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 7/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/96:25 am
PHL
- STL
1 stop27h 32m
Frontier
Mon 8/104:57 pm
STL
- PHL
1 stop13h 18m
Frontier
Deal found 7/19![Frontier logo]()
$129
This Kiwi.com deal was found by Cheapflights users on 7/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/96:25 am
PHL
- STL
1 stop27h 32m
Frontier
Thu 8/136:34 pm
STL
- PHL
1 stop11h 41m
Frontier
Deal found 7/19![Frontier logo]()
$130
This Kiwi.com deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/116:25 am
PHL
- STL
1 stop27h 32m
Frontier
Thu 8/136:34 pm
STL
- PHL
1 stop11h 41m
Frontier
Deal found 7/22![Frontier logo]()
$118
This Kiwi.com deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/136:25 am
PHL
- STL
1 stop12h 12m
Frontier
Mon 8/174:57 pm
STL
- PHL
1 stop18h 29m
Frontier
Deal found 7/22![Frontier logo]()
$117
This Kiwi.com deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/218:30 am
PHL
- STL
1 stop9h 52m
Frontier
Fri 8/286:17 pm
STL
- PHL
1 stop11h 58m
Frontier
Deal found 7/22![Frontier logo]()
$139
This Expedia deal was found by Cheapflights users on 7/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/225:55 am
EWR
- MCI
1 stop11h 10m
Frontier
Mon 8/2411:26 am
MCI
- EWR
1 stop12h 37m
Frontier
Deal found 7/19![Frontier logo]()
$254
This Kiwi.com deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/248:30 am
PHL
- STL
1 stop9h 52m
Frontier
Mon 10/510:35 am
STL
- PHL
1 stop6h 40m
Frontier
Deal found 7/21![Frontier logo]()
$124
This Kiwi.com deal was found by Cheapflights users on 7/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/264:45 pm
PHL
- STL
1 stop25h 37m
Frontier
Tue 9/2210:35 am
STL
- PHL
1 stop25h 37m
Frontier
Deal found 7/18![Frontier logo]()
$122
This Kiwi.com deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/276:30 am
PHL
- STL
1 stop11h 52m
Frontier
Sun 8/306:17 pm
STL
- PHL
1 stop11h 58m
Frontier
Deal found 7/22![Frontier logo]()
$119
This Kiwi.com deal was found by Cheapflights users on 7/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/278:30 am
PHL
- STL
1 stop9h 52m
Frontier
Mon 8/316:17 pm
STL
- PHL
1 stop11h 58m
Frontier
Deal found 7/20![Frontier logo]()
$121
This Kiwi.com deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/286:30 am
PHL
- STL
1 stop11h 52m
Frontier
Tue 10/610:35 am
STL
- PHL
1 stop6h 40m
Frontier
Deal found 7/21![Frontier logo]()
$125
This CheapOair deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/287:00 am
DCA
- STL
1 stop13h 13m
Frontier
Mon 8/317:58 pm
STL
- DCA
1 stop25h 01m
Frontier
Deal found 7/22![Frontier logo]()
$254
One-way flights from Pennsylvania to MissouriSearch for one-way flight options from Pennsylvania to Missouri. Find affordable one-way fares based on user searches. Data last updated July 23, 2026.
Search for one-way flight options from Pennsylvania to Missouri. Find affordable one-way fares based on user searches. Data last updated July 23, 2026.
This Kiwi.com deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/2212:43 pm
PHL
- STL
1 stop21h 57m
Frontier
Deal found 7/22![Frontier logo]()
$52
This Kiwi.com deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/194:45 pm
PHL
- STL
1 stop25h 37m
Frontier
Deal found 7/22![Frontier logo]()
$57
This Kiwi.com deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/195:28 pm
PHL
- STL
1 stop17h 12m
Frontier
Deal found 7/22![Frontier logo]()
$58
This Kiwi.com deal was found by Cheapflights users on 7/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/136:25 am
PHL
- STL
1 stop12h 12m
Frontier
Deal found 7/20![Frontier logo]()
$60
This Kiwi.com deal was found by Cheapflights users on 7/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/265:38 pm
PHL
- STL
1 stop17h 02m
Frontier
Deal found 7/19![Frontier logo]()
$61
This Kiwi.com deal was found by Cheapflights users on 7/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/146:25 am
PHL
- STL
1 stop27h 32m
Frontier
Deal found 7/20![Frontier logo]()
$62
This Kiwi.com deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/166:25 am
PHL
- STL
1 stop27h 32m
Frontier
Deal found 7/21![Frontier logo]()
$64
This Kiwi.com deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/95:38 pm
PHL
- STL
1 stop17h 02m
Frontier
Deal found 7/21![Frontier logo]()
$65
This Kiwi.com deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/289:16 pm
IAD
- STL
1 stop13h 24m
Frontier
Deal found 7/22![Frontier logo]()
$69
This Trip.com deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/206:20 am
IAD
- STL
1 stop12h 02m
Frontier
Deal found 7/22![Frontier logo]()
$71
This Kiwi.com deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/298:39 pm
IAD
- STL
1 stop21h 43m
Frontier
Deal found 7/22![Frontier logo]()
$74
This Kiwi.com deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/236:30 am
PHL
- STL
1 stop11h 52m
Frontier
Deal found 7/21![Frontier logo]()
$74
Find flight deals from Pennsylvania to Missouri
Keep the following information in mind while searching for Pennsylvania to Missouri flight deals. Data was last updated July 23, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $99 (Kiwi.com) |
One-way from | $52 (Kiwi.com) |
Popular in | June |
Cheapest in | September |
Average price | $476 |
Good round-trip deal | $321 or less |
Good one-way deal | $229 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Pennsylvania to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 23, 2026.
Use the filters below to find and compare flights from Pennsylvania to Missouri that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Washington, D.C.St. Louis
IAD - STL
IADSTL
Washington, D.C. Dulles Intl
Sat 8/15
5:47 pm-11:31 pm
1 stop6h 44m
Lambert-St Louis
Mon 8/17
12:52 pm-6:28 pm
1 stop4h 36m
$257
Washington, D.C.St. Louis
IAD - STL
IADSTL
Washington, D.C. Dulles Intl
Tue 8/18
5:15 pm-10:00 pm
1 stop5h 45m
Lambert-St Louis
Tue 8/25
7:25 am-1:55 pm
1 stop5h 30m
$257
Washington, D.C.St. Louis
DCA - STL
DCASTL
Washington, D.C. Reagan-National
Mon 8/17
7:25 am-10:30 am
1 stop4h 05m
Lambert-St Louis
Wed 8/19
3:05 pm-10:05 pm
1 stop6h 00m
$257
Washington, D.C.St. Louis
DCA - STL
DCASTL
Washington, D.C. Reagan-National
Thu 10/8
3:25 pm-4:55 pm
Nonstop2h 30m
Lambert-St Louis
Sat 10/10
3:00 pm-6:00 pm
Nonstop2h 00m
$269
PhiladelphiaSt. Louis
PHL - STL
PHLSTL
Philadelphia
Wed 8/12
2:45 pm-4:05 pm
Nonstop2h 20m
Lambert-St Louis
Thu 8/13
7:05 pm-10:15 pm
Nonstop2h 10m
$277
Washington, D.C.St. Louis
DCA - STL
DCASTL
Washington, D.C. Reagan-National
Mon 8/10
6:55 am-10:10 am
1 stop4h 15m
Lambert-St Louis
Mon 8/17
7:55 pm-10:55 pm
Nonstop2h 00m
$279
Washington, D.C.Kansas City
IAD - MCI
IADMCI
Washington, D.C. Dulles Intl
Wed 9/30
6:00 am-11:15 am
1 stop6h 15m
Kansas City
Mon 10/5
2:26 pm-9:44 pm
1 stop6h 18m
$281
Washington, D.C.St. Louis
DCA - STL
DCASTL
Washington, D.C. Reagan-National
Thu 8/27
8:15 am-9:35 am
Nonstop2h 20m
Lambert-St Louis
Sat 8/29
5:05 am-1:55 pm
2 stops7h 50m
$284
PhiladelphiaSt. Louis
PHL - STL
PHLSTL
Philadelphia
Wed 10/7
7:00 am-11:45 am
1 stop5h 45m
Lambert-St Louis
Sat 10/10
4:55 pm-8:00 pm
Nonstop2h 05m
$287
PhiladelphiaSt. Louis
PHL - STL
PHLSTL
Philadelphia
Sat 10/10
5:55 am-9:15 am
1 stop4h 20m
Lambert-St Louis
Mon 10/12
7:50 pm-11:10 pm
Nonstop2h 20m
$287
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from Pennsylvania to Missouri
Have a flexible travel schedule? Discover the best time to fly to Missouri from Pennsylvania with our price prediction graph.
PHL-STL
IAD-STL
EWR-MCI
DCA-STL
IAD-MCI
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Pennsylvania to Missouri
USPA-USMO
PHL-STL
IAD-STL
EWR-MCI
DCA-STL
What is the cheapest month to book a flight from Pennsylvania to Missouri?
Currently, January is the cheapest month in which you can book a flight from Pennsylvania to Missouri (average of $362). Flying from Pennsylvania to Missouri in June is currently the most expensive (average of $493). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from PA to MO?
Find hourly flight availability from Pennsylvania to Missouri. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated July 23, 2026.
It’s optimal to fly from Pennsylvania to Missouri in the afternoon. By choosing this option you can save up to 14% on the cost of your flight, compared to a flight in the morning.
Weekly flight availability from Pennsylvania to Missouri
Explore weekly flight availability from Pennsylvania to Missouri. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated July 23, 2026.
The most flights from USPA to USMO are scheduled on a Monday (8 on average). You will have fewer flight options on Saturday, which is when the least amount of flights are scheduled (5 on average).
How much does it cost to fly round-trip from Pennsylvania to Missouri?
How far ahead should I book a flight from Pennsylvania to Missouri?
Booking 73 days in advance of your planned departure date is, on average, the best time to get cheap flights from Pennsylvania to Missouri. The general trend is that the closer you book to the departure date, the more expensive your flight will be.
What is the cheapest day to fly from Pennsylvania to Missouri?
Use this chart to determine the cheapest time to fly round-trip from Pennsylvania to Missouri. Price data was last updated on July 18, 2026.
Travelers seeking maximum savings on their Pennsylvania to Missouri flight should consider departing on Thursday at noon when fares are most often at their lowest. Sunday afternoons flights should be avoided if possible as fares are typically the most expensive at this time.
Reviews of airlines servicing Missouri
Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated July 23, 2026.
Read through reviews of airlines operating flights from Pennsylvania to Missouri, such as Southwest,Delta, andUnited Airlines. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Crew
8.6
Entertainment
7.5
Overall
8.0
Food
7.0
Boarding
8.1
Comfort
8.0
Reviews
1 / 20
2.0
MediocreAnonymous,Feb 2025
MCO - STL
Crew
8.6
Entertainment
7.5
Overall
8.0
Food
7.0
Boarding
8.1
Comfort
8.0
Reviews
1 / 20
2.0
MediocreAnonymous,Feb 2025
MCO - STL
Crew
8.6
Entertainment
7.5
Overall
8.0
Food
7.0
Boarding
8.1
Comfort
8.0
Reviews
1 / 20
2.0
MediocreAnonymous,Feb 2025
MCO - STL
Crew
8.6
Entertainment
7.5
Overall
8.0
Food
7.0
Boarding
8.1
Comfort
8.0
Reviews
1 / 20
2.0
MediocreAnonymous,Feb 2025
MCO - STL
Crew
8.6
Entertainment
7.5
Overall
8.0
Food
7.0
Boarding
8.1
Comfort
8.0
Reviews
1 / 20
2.0
MediocreAnonymous,Feb 2025
MCO - STL
Crew
8.6
Entertainment
7.5
Overall
8.0
Food
7.0
Boarding
8.1
Comfort
8.0
Reviews
1 / 20
2.0
MediocreAnonymous,Feb 2025
MCO - STL
Related info for your journey
Find useful and relevant information for your journey from Pennsylvania to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Complete your trip
Flights by cabin class
Other flight options
Popular flights
Return Flight Options
Top destinations
Alternative routes for Pennsylvania to Missouri
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Missouri by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Pennsylvania to Missouri by cabin class
Find flights from Pennsylvania to Missouri, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Pennsylvania and Missouri flights
Browse other Pennsylvania and Missouri flight options. Last updated on July 23, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Find a return flight route from Missouri
Find the right flight back to Pennsylvania after your stay in Missouri
Pennsylvania to Missouri flights
Consider these flights traveling from Pennsylvania to Missouri.
Top 6 airlines flying from Pennsylvania to Missouri
Discover the top 6 airlines that operate flights from Pennsylvania to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 23, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$144 | Average$244 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$158 | Average$421 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$188 | Average$395 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$227 | Average$425 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$248 | Average$423 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$358 | Average$433 | FlexibilityNo cancel fee | On-time62% |