$70+ Cheap flights from Pennsylvania to Missouri
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/8. Fares are subject to change and may not be available on all flights or dates of travel.
PHL — STL
Apr 23 — Apr 301
Round-trip
1 adult, Economy
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Find cheap flights from Pennsylvania to Missouri with Cheapflights
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Cheapest flights from Pennsylvania to MissouriExplore the most affordable flight options available from Pennsylvania to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 24, 2026.
Explore the most affordable flight options available from Pennsylvania to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 24, 2026.
This Frontier deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/195:59 am
EWR
- MCI
1 stop5h 59m
Frontier
Fri 4/2411:19 am
MCI
- EWR
1 stop9h 10m
Frontier
Deal found 3/23![Frontier logo]()
$180
This Frontier deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/165:59 am
EWR
- MCI
1 stop5h 59m
Frontier
Fri 4/2411:19 am
MCI
- EWR
1 stop9h 10m
Frontier
Deal found 3/20![Frontier logo]()
$200
This Frontier deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/195:59 am
EWR
- MCI
1 stop5h 59m
Frontier
Mon 4/2011:13 am
MCI
- EWR
1 stop9h 16m
Frontier
Deal found 3/20![Frontier logo]()
$201
This Frontier deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/235:59 am
EWR
- MCI
1 stop5h 59m
Frontier
Thu 4/3011:53 am
MCI
- EWR
1 stop12h 23m
Frontier
Deal found 3/24![Frontier logo]()
$203
This Expedia deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/85:55 pm
EWR
- MCI
1 stop6h 58m
Multiple Airlines
Fri 5/111:19 am
MCI
- EWR
1 stop9h 10m
Multiple Airlines
Deal found 3/20![Multiple Airlines logo]()
$208
This Frontier deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/165:59 am
EWR
- MCI
1 stop5h 59m
Frontier
Mon 4/2711:13 am
MCI
- EWR
1 stop9h 16m
Frontier
Deal found 3/20![Frontier logo]()
$221
This CheapOair deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/112:54 pm
EWR
- MCI
1 stop9h 59m
Spirit Airlines
Tue 4/146:04 pm
MCI
- EWR
1 stop11h 51m
Spirit Airlines
Deal found 3/20![Spirit Airlines logo]()
$227
This Booking.com deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/165:59 am
EWR
- MCI
1 stop5h 59m
Frontier
Thu 4/2311:53 am
MCI
- EWR
1 stop12h 23m
Frontier
Deal found 3/19![Frontier logo]()
$228
This Priceline deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/65:59 am
EWR
- MCI
1 stop10h 37m
Frontier
Fri 4/2411:19 am
MCI
- EWR
1 stop9h 10m
Frontier
Deal found 3/19![Frontier logo]()
$235
This Frontier deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/65:55 am
EWR
- MCI
1 stop12h 34m
Frontier
Mon 5/116:24 pm
MCI
- EWR
1 stop5h 54m
Frontier
Deal found 3/23![Frontier logo]()
$242
This Frontier deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/185:55 am
EWR
- MCI
1 stop12h 34m
Frontier
Wed 5/206:24 pm
MCI
- EWR
1 stop5h 54m
Frontier
Deal found 3/20![Frontier logo]()
$243
This Southwest deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/156:55 am
DCA
- STL
1 stop7h 50m
Southwest
Wed 5/208:25 am
STL
- DCA
1 stop6h 35m
Southwest
Deal found 3/23![Southwest logo]()
$274
Best flights from Pennsylvania to MissouriDiscover carefully curated flight deals from Pennsylvania to Missouri that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 24, 2026.
Discover carefully curated flight deals from Pennsylvania to Missouri that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 24, 2026.
This Southwest deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/2111:40 am
DCA
- STL
2 stops7h 20m
Southwest
Fri 4/241:45 pm
STL
- DCA
1 stop5h 10m
Southwest
Deal found 3/22![Southwest logo]()
$279
This Delta deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/47:38 pm
DCA
- STL
1 stop4h 58m
Delta
Sat 5/91:05 pm
STL
- DCA
1 stop6h 08m
Delta
Deal found 3/19![Delta logo]()
$285
This United Airlines deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/169:00 am
IAD
- STL
Nonstop2h 28m
United Airlines
Sun 4/196:30 am
STL
- IAD
1 stop4h 18m
United Airlines
Deal found 3/19![United Airlines logo]()
$333
This Southwest deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/68:00 am
DCA
- STL
Nonstop2h 10m
Southwest
Mon 6/87:55 pm
STL
- DCA
Nonstop2h 00m
Southwest
Deal found 3/23![Southwest logo]()
$279
This Delta deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/15:30 pm
LGA
- STL
Nonstop2h 56m
Delta
Wed 5/612:45 pm
STL
- LGA
Nonstop2h 30m
Delta
Deal found 3/19![Delta logo]()
$295
This Southwest deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/214:30 pm
IAD
- STL
1 stop7h 40m
Southwest
Fri 4/243:00 pm
STL
- IAD
1 stop8h 20m
Southwest
Deal found 3/22![Southwest logo]()
$289
This Alaska Airlines deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/227:00 am
JFK
- MCI
1 stop17h 59m
Alaska Airlines
Wed 5/67:00 am
MCI
- JFK
2 stops22h 03m
Alaska Airlines
Deal found 3/22![Alaska Airlines logo]()
$638
This Delta deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/285:30 pm
LGA
- STL
Nonstop2h 56m
Delta
Sun 5/36:05 am
STL
- LGA
Nonstop2h 30m
Delta
Deal found 3/19![Delta logo]()
$295
This United Airlines deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/26:10 am
IAD
- STL
1 stop5h 24m
United Airlines
Sat 7/41:13 pm
STL
- IAD
1 stop4h 49m
United Airlines
Deal found 3/21![United Airlines logo]()
$335
This Southwest deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/207:45 pm
DCA
- STL
1 stop4h 00m
Southwest
Sat 4/256:10 am
STL
- DCA
2 stops9h 05m
Southwest
Deal found 3/23![Southwest logo]()
$294
This United Airlines deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/229:00 am
IAD
- STL
Nonstop2h 28m
United Airlines
Wed 4/2911:15 am
STL
- IAD
1 stop5h 13m
United Airlines
Deal found 3/23![United Airlines logo]()
$345
This Delta deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/196:20 am
DCA
- STL
1 stop7h 03m
Delta
Thu 5/211:27 pm
STL
- DCA
1 stop7h 18m
Delta
Deal found 3/21![Delta logo]()
$325
This Southwest deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/116:10 pm
DCA
- STL
1 stop7h 30m
Southwest
Mon 6/155:00 am
STL
- DCA
1 stop6h 05m
Southwest
Deal found 3/22![Southwest logo]()
$299
This United Airlines deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/223:15 pm
EWR
- MCI
1 stop5h 30m
United Airlines
Sun 4/266:15 am
MCI
- EWR
1 stop5h 05m
United Airlines
Deal found 3/23![United Airlines logo]()
$345
This Delta deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/63:00 pm
IAD
- MCI
1 stop6h 10m
Delta
Sun 5/105:13 pm
MCI
- IAD
1 stop6h 38m
Delta
Deal found 3/23![Delta logo]()
$328
This Southwest deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/66:10 am
DCA
- STL
1 stop7h 50m
Southwest
Sun 5/107:20 pm
STL
- DCA
Nonstop2h 00m
Southwest
Deal found 3/23![Southwest logo]()
$301
This United Airlines deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/218:05 am
LGA
- STL
1 stop5h 06m
United Airlines
Fri 5/296:00 am
STL
- LGA
1 stop5h 23m
United Airlines
Deal found 3/19![United Airlines logo]()
$350
This Delta deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/285:21 pm
IAD
- STL
1 stop4h 48m
Delta
Tue 6/26:04 pm
STL
- IAD
1 stop3h 52m
Delta
Deal found 3/23![Delta logo]()
$335
This Southwest deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/136:10 am
DCA
- STL
1 stop7h 50m
Southwest
Thu 5/218:35 am
STL
- DCA
Nonstop2h 00m
Southwest
Deal found 3/21![Southwest logo]()
$315
This United Airlines deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/610:31 am
IAD
- STL
1 stop6h 15m
United Airlines
Wed 8/128:44 am
STL
- IAD
Nonstop2h 11m
United Airlines
Deal found 3/22![United Airlines logo]()
$355
This Delta deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/206:35 pm
JFK
- STL
1 stop6h 01m
Delta
Sat 4/256:48 am
STL
- JFK
1 stop4h 03m
Delta
Deal found 3/19![Delta logo]()
$335
This Southwest deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/246:35 pm
LGA
- STL
Nonstop2h 55m
Southwest
Mon 4/273:30 pm
STL
- LGA
Nonstop2h 25m
Southwest
Deal found 3/19![Southwest logo]()
$316
This United Airlines deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/179:59 pm
EWR
- STL
Nonstop2h 58m
United Airlines
Sun 4/196:15 am
STL
- EWR
Nonstop2h 36m
United Airlines
Deal found 3/23![United Airlines logo]()
$355
This Delta deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/2510:06 am
LGA
- STL
Nonstop2h 59m
Delta
Mon 4/276:25 am
STL
- LGA
Nonstop2h 30m
Delta
Deal found 3/22![Delta logo]()
$344
This Southwest deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/126:35 pm
PHL
- STL
Nonstop2h 25m
Southwest
Sat 5/166:55 pm
STL
- PHL
Nonstop2h 10m
Southwest
Deal found 3/23![Southwest logo]()
$322
This United Airlines deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/269:00 am
IAD
- STL
Nonstop2h 28m
United Airlines
Mon 4/279:10 am
STL
- IAD
1 stop6h 59m
United Airlines
Deal found 3/22![United Airlines logo]()
$358
This Southwest deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/48:00 am
DCA
- STL
Nonstop2h 10m
Southwest
Sun 6/78:15 am
STL
- DCA
Nonstop1h 55m
Southwest
Deal found 3/19![Southwest logo]()
$323
This Delta deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/187:38 pm
IAD
- STL
1 stop5h 21m
Delta
Thu 5/211:27 pm
STL
- IAD
1 stop6h 57m
Delta
Deal found 3/21![Delta logo]()
$357
This United Airlines deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/169:00 am
IAD
- STL
Nonstop2h 28m
United Airlines
Sat 4/1811:15 am
STL
- IAD
1 stop7h 08m
United Airlines
Deal found 3/22![United Airlines logo]()
$359
This Alaska Airlines deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/287:00 am
JFK
- STL
1 stop17h 59m
Alaska Airlines
Wed 4/297:00 am
STL
- JFK
1 stop14h 59m
Alaska Airlines
Deal found 3/23![Alaska Airlines logo]()
$703
Last-minute flights from Pennsylvania to MissouriDiscover last-minute flight deals from Pennsylvania to Missouri. Data last updated March 24, 2026 and is based on user searches.
Discover last-minute flight deals from Pennsylvania to Missouri. Data last updated March 24, 2026 and is based on user searches.
This Priceline deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/65:59 am
EWR
- MCI
1 stop10h 37m
Frontier
Fri 4/2411:19 am
MCI
- EWR
1 stop9h 10m
Frontier
Deal found 3/19![Frontier logo]()
$235
This Kiwi.com deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/75:55 pm
EWR
- MCI
1 stop6h 58m
Spirit Airlines
Tue 4/146:04 pm
MCI
- EWR
1 stop11h 51m
Spirit Airlines
Deal found 3/19![Spirit Airlines logo]()
$217
This Kiwi.com deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/85:55 pm
EWR
- MCI
1 stop6h 58m
Spirit Airlines
Tue 4/146:04 pm
MCI
- EWR
1 stop11h 51m
Spirit Airlines
Deal found 3/19![Spirit Airlines logo]()
$194
This Expedia deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/85:55 pm
EWR
- MCI
1 stop6h 58m
Multiple Airlines
Fri 5/111:19 am
MCI
- EWR
1 stop9h 10m
Multiple Airlines
Deal found 3/20![Multiple Airlines logo]()
$208
This Kiwi.com deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/95:55 pm
EWR
- MCI
1 stop6h 58m
Multiple Airlines
Fri 4/104:31 pm
MCI
- EWR
1 stop14h 20m
Multiple Airlines
Deal found 3/19![Multiple Airlines logo]()
$231
This CheapOair deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/112:54 pm
EWR
- MCI
1 stop9h 59m
Spirit Airlines
Tue 4/146:04 pm
MCI
- EWR
1 stop11h 51m
Spirit Airlines
Deal found 3/20![Spirit Airlines logo]()
$227
This Frontier deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/165:59 am
EWR
- MCI
1 stop5h 59m
Frontier
Fri 4/2411:19 am
MCI
- EWR
1 stop9h 10m
Frontier
Deal found 3/20![Frontier logo]()
$200
This Frontier deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/165:59 am
EWR
- MCI
1 stop5h 59m
Frontier
Mon 4/2711:13 am
MCI
- EWR
1 stop9h 16m
Frontier
Deal found 3/20![Frontier logo]()
$221
This Booking.com deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/165:59 am
EWR
- MCI
1 stop5h 59m
Frontier
Thu 4/2311:53 am
MCI
- EWR
1 stop12h 23m
Frontier
Deal found 3/19![Frontier logo]()
$228
This Frontier deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/195:59 am
EWR
- MCI
1 stop5h 59m
Frontier
Fri 4/2411:19 am
MCI
- EWR
1 stop9h 10m
Frontier
Deal found 3/23![Frontier logo]()
$180
This Frontier deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/195:59 am
EWR
- MCI
1 stop5h 59m
Frontier
Mon 4/2011:13 am
MCI
- EWR
1 stop9h 16m
Frontier
Deal found 3/20![Frontier logo]()
$201
This Frontier deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/195:59 am
EWR
- MCI
1 stop5h 59m
Frontier
Mon 4/2711:13 am
MCI
- EWR
1 stop9h 16m
Frontier
Deal found 3/23![Frontier logo]()
$225
One-way flights from Pennsylvania to MissouriSearch for one-way flight options from Pennsylvania to Missouri. Find affordable one-way fares based on user searches. Data last updated March 24, 2026.
Search for one-way flight options from Pennsylvania to Missouri. Find affordable one-way fares based on user searches. Data last updated March 24, 2026.
This Kiwi.com deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/83:15 pm
IAD
- STL
1 stop27h 19m
Frontier
Deal found 3/19![Frontier logo]()
$70
This Frontier deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/254:42 pm
PHL
- STL
1 stop7h 37m
Frontier
Deal found 3/23![Frontier logo]()
$70
This Kiwi.com deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/1410:29 pm
EWR
- STL
1 stop9h 21m
Frontier
Deal found 3/20![Frontier logo]()
$71
This Frontier deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/111:36 pm
IAD
- STL
1 stop10h 49m
Frontier
Deal found 3/19![Frontier logo]()
$76
This Frontier deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/136:15 am
IAD
- MCI
1 stop10h 21m
Frontier
Deal found 3/23![Frontier logo]()
$76
This Frontier deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/188:00 am
DCA
- STL
1 stop12h 32m
Frontier
Deal found 3/20![Frontier logo]()
$76
This Frontier deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/1710:29 pm
EWR
- STL
1 stop9h 21m
Frontier
Deal found 3/24![Frontier logo]()
$76
This Expedia deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/287:56 pm
PHL
- STL
1 stop28h 23m
Frontier
Deal found 3/23![Frontier logo]()
$76
This Booking.com deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/291:45 pm
EWR
- STL
1 stop10h 34m
Frontier
Deal found 3/23![Frontier logo]()
$77
This Kiwi.com deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/146:05 am
IAD
- STL
1 stop25h 45m
Frontier
Deal found 3/21![Frontier logo]()
$78
This Expedia deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/2010:38 pm
PHL
- STL
1 stop25h 41m
Frontier
Deal found 3/20![Frontier logo]()
$78
This Super.com deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/85:55 pm
EWR
- MCI
1 stop6h 58m
Spirit Airlines
Deal found 3/23![Spirit Airlines logo]()
$80
Find flight deals from Pennsylvania to Missouri
Keep the following information in mind while searching for Pennsylvania to Missouri flight deals. Data was last updated March 24, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $180 (Frontier) |
One-way from | $70 (Kiwi.com) |
Popular in | May |
Cheapest in | September |
Average price | $401 |
Good round-trip deal | $344 or less |
Good one-way deal | $170 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Pennsylvania to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 24, 2026.
Use the filters below to find and compare flights from Pennsylvania to Missouri that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Washington, D.C.St. Louis
DCA - STL
DCASTL
Washington, D.C. Reagan-National
Tue 4/21
11:40 am-6:00 pm
2 stops7h 20m
Lambert-St Louis
Fri 4/24
1:45 pm-7:55 pm
1 stop5h 10m
$279
Washington, D.C.St. Louis
DCA - STL
DCASTL
Washington, D.C. Reagan-National
Sat 6/6
8:00 am-9:10 am
Nonstop2h 10m
Lambert-St Louis
Mon 6/8
7:55 pm-10:55 pm
Nonstop2h 00m
$279
Washington, D.C.St. Louis
DCA - STL
DCASTL
Washington, D.C. Reagan-National
Mon 5/4
7:38 pm-11:36 pm
1 stop4h 58m
Lambert-St Louis
Sat 5/9
1:05 pm-8:13 pm
1 stop6h 08m
$285
Washington, D.C.St. Louis
IAD - STL
IADSTL
Washington, D.C. Dulles Intl
Tue 4/21
4:30 pm-11:10 pm
1 stop7h 40m
Lambert-St Louis
Fri 4/24
3:00 pm-12:20 am
1 stop8h 20m
$289
Washington, D.C.St. Louis
DCA - STL
DCASTL
Washington, D.C. Reagan-National
Mon 4/20
7:45 pm-10:45 pm
1 stop4h 00m
Lambert-St Louis
Sat 4/25
6:10 am-4:15 pm
2 stops9h 05m
$294
New YorkSt. Louis
LGA - STL
LGASTL
New York LaGuardia
Fri 5/1
5:30 pm-7:26 pm
Nonstop2h 56m
Lambert-St Louis
Wed 5/6
12:45 pm-4:15 pm
Nonstop2h 30m
$295
New YorkSt. Louis
LGA - STL
LGASTL
New York LaGuardia
Tue 4/28
5:30 pm-7:26 pm
Nonstop2h 56m
Lambert-St Louis
Sun 5/3
6:05 am-9:35 am
Nonstop2h 30m
$295
Washington, D.C.St. Louis
DCA - STL
DCASTL
Washington, D.C. Reagan-National
Thu 6/11
6:10 pm-12:40 am
1 stop7h 30m
Lambert-St Louis
Mon 6/15
5:00 am-12:05 pm
1 stop6h 05m
$299
Washington, D.C.St. Louis
DCA - STL
DCASTL
Washington, D.C. Reagan-National
Wed 5/6
6:10 am-1:00 pm
1 stop7h 50m
Lambert-St Louis
Sun 5/10
7:20 pm-10:20 pm
Nonstop2h 00m
$301
Washington, D.C.St. Louis
DCA - STL
DCASTL
Washington, D.C. Reagan-National
Wed 5/13
6:10 am-1:00 pm
1 stop7h 50m
Lambert-St Louis
Thu 5/21
8:35 am-11:35 am
Nonstop2h 00m
$315
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from Pennsylvania to Missouri
Have a flexible travel schedule? Discover the best time to fly to Missouri from Pennsylvania with our price prediction graph.
DCA-STL
PHL-STL
EWR-MCI
IAD-STL
EWR-STL
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Pennsylvania to Missouri
USPA-USMO
DCA-STL
PHL-STL
EWR-MCI
IAD-STL
What is the cheapest month to book a flight from Pennsylvania to Missouri?
Currently, November is the cheapest month in which you can book a flight from Pennsylvania to Missouri (average of $156). Flying from Pennsylvania to Missouri in March is currently the most expensive (average of $248). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from PA to MO?
Find hourly flight availability from Pennsylvania to Missouri. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated March 24, 2026.
It’s optimal to fly from Pennsylvania to Missouri in the afternoon. By choosing this option you can save up to 11% on the cost of your flight, compared to a flight in the morning.
What is the cheapest day to fly from Pennsylvania to Missouri?
Use this chart to determine the cheapest time to fly round-trip from Pennsylvania to Missouri. Price data was last updated on March 23, 2026.
Travelers seeking maximum savings on their Pennsylvania to Missouri flight should consider departing on Tuesday afternoons when fares are most often at their lowest. Sunday afternoons flights should be avoided if possible as fares are typically the most expensive at this time.
Weekly flight availability from Pennsylvania to Missouri
Explore weekly flight availability from Pennsylvania to Missouri. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated March 24, 2026.
The most flights from USPA to USMO are scheduled on a Monday (7 on average). You will have fewer flight options on Saturday, which is when the least amount of flights are scheduled (1 on average).
Reviews of airlines servicing Missouri
Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated March 24, 2026.
Read through reviews of airlines operating flights from Pennsylvania to Missouri, such as Southwest,Delta, andUnited Airlines. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Boarding
8.1
Crew
8.6
Food
7.0
Comfort
8.0
Entertainment
7.5
Overall
8.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Boarding
8.1
Crew
8.6
Food
7.0
Comfort
8.0
Entertainment
7.5
Overall
8.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Boarding
8.1
Crew
8.6
Food
7.0
Comfort
8.0
Entertainment
7.5
Overall
8.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Boarding
8.1
Crew
8.6
Food
7.0
Comfort
8.0
Entertainment
7.5
Overall
8.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Boarding
8.1
Crew
8.6
Food
7.0
Comfort
8.0
Entertainment
7.5
Overall
8.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Boarding
8.1
Crew
8.6
Food
7.0
Comfort
8.0
Entertainment
7.5
Overall
8.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Related info for your journey
Find useful and relevant information for your journey from Pennsylvania to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Pennsylvania to Missouri
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Missouri by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Pennsylvania to Missouri by cabin class
Find flights from Pennsylvania to Missouri, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Pennsylvania and Missouri flights
Browse other Pennsylvania and Missouri flight options. Last updated on March 24, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Find a return flight route from Missouri
Find the right flight back to Pennsylvania after your stay in Missouri
Pennsylvania to Missouri flights
Consider these flights traveling from Pennsylvania to Missouri.
Top 6 airlines flying from Pennsylvania to Missouri
Discover the top 6 airlines that operate flights from Pennsylvania to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 24, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$93 | Average$178 | FlexibilityNo cancel fee | On-time65% | |
| Cheapest$135 | Average$248 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$170 | Average$397 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$219 | Average$385 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$235 | Average$406 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$248 | Average$420 | FlexibilityNo cancel fee | On-time69% |