How popular is this Pennsylvania to Missouri flight route?

Flights from Pennsylvania to Missouri have been viewed 41 times in the past calendar month.

How long is the flight from Pennsylvania to Missouri?

A quick flight from Pennsylvania to Missouri can take about 5h 54m. Frontier provides one of the quickest options available for as low as $261. There are 869 mi between Pennsylvania and Missouri. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

In terms of precipitation, rainfall in Missouri ranges from 2.2 - 4.7 inches per month. May is typically the wettest month, when rainfall can reach 4.7 in. February is typically the driest time to visit Missouri when rainfall is around 2.2 in.

If weather is an important factor for your trip to Missouri, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 80.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 32.0 F).

Can I find deals for flights from Pennsylvania to Missouri that include hotel bookings?

Yes. In addition to deals on Pennsylvania to Missouri flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Pennsylvania to Missouri?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Pennsylvania to Missouri.

Can I find deals for business class flights from Pennsylvania to Missouri?

Yes. Cheapflights offers flight deals from Pennsylvania to Missouri by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$60+ Flights from Pennsylvania to Missouri

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1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

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Cheap flight deals from Pennsylvania to Missouri

Cheapest flights from Pennsylvania to Missouri
Explore the most affordable flight options available from Pennsylvania to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 23, 2025.

Wed 12/3110:30 pmEWR - STL

1 stop12h 10mFrontier

Sun 1/410:57 amSTL - EWR

1 stop9h 38mFrontier

Deal found 12/22

$231

Wed 12/316:00 amPHL - STL

2 stops28h 40mMultiple Airlines

Mon 1/125:11 pmSTL - PHL

1 stop27h 52mMultiple Airlines

Deal found 12/21

$241

Tue 12/3010:30 pmEWR - MCI

1 stop12h 38mFrontier

Mon 1/511:38 amMCI - EWR

1 stop8h 57mFrontier

Deal found 12/22

$242

Thu 12/258:00 amDCA - STL

1 stop27h 02mFrontier

Mon 1/57:43 pmSTL - DCA

1 stop16h 19mFrontier

Deal found 12/21

$269

Wed 12/318:35 amIAD - STL

Nonstop2h 33mUnited Airlines

Wed 12/316:35 pmSTL - IAD

1 stop4h 40mUnited Airlines

Deal found 12/21

$272

Wed 12/316:10 pmDCA - STL

Nonstop2h 25mSouthwest

Thu 1/18:25 amSTL - DCA

1 stop5h 15mSouthwest

Deal found 12/21

$272

Wed 12/316:20 amJFK - STL

1 stop28h 20mFrontier

Sun 1/410:57 amSTL - JFK

1 stop21h 04mFrontier

Deal found 12/22

$274

Wed 12/3112:00 pmLGA - STL

1 stop11h 33mFrontier

Sun 1/410:57 amSTL - LGA

1 stop11h 17mFrontier

Deal found 12/21

$277

Wed 12/317:10 amPHL - STL

1 stop10h 14mFrontier

Mon 1/128:50 amSTL - PHL

1 stop10h 19mFrontier

Deal found 12/21

$282

Sun 12/289:58 pmIAD - STL

1 stop12h 47mFrontier

Thu 1/110:42 amSTL - IAD

1 stop6h 34mFrontier

Deal found 12/21

$283

Tue 12/309:30 amEWR - STL

Nonstop3h 07mUnited Airlines

Thu 1/17:00 amSTL - EWR

Nonstop2h 34mUnited Airlines

Deal found 12/22

$283

Wed 12/316:00 amPHL - STL

2 stops28h 40mFrontier

Sun 1/115:11 pmSTL - PHL

1 stop14h 26mFrontier

Deal found 12/21

$285

Best flights from Pennsylvania to Missouri
Discover carefully curated flight deals from Pennsylvania to Missouri that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated December 23, 2025.

Tue 1/206:20 pmPHL - STL

1 stop13h 31mFrontier

Tue 1/275:42 pmSTL - PHL

1 stop15h 55mFrontier

Deal found 12/23

$131

Tue 1/202:36 pmPHL - STL

1 stop17h 15mMultiple Airlines

Tue 1/275:42 pmSTL - PHL

2 stops20h 58mMultiple Airlines

Deal found 12/23

$158

Wed 1/75:51 amEWR - MCI

1 stop12h 19mSpirit Airlines

Mon 1/1211:26 amMCI - EWR

1 stop23h 16mSpirit Airlines

Deal found 12/23

$185

Tue 5/128:00 amEWR - STL

1 stop5h 54mDelta

Wed 5/136:45 amSTL - EWR

1 stop4h 19mDelta

Deal found 12/22

$261

Thu 1/2911:00 amDCA - STL

2 stops7h 05mSouthwest

Sat 1/318:50 amSTL - DCA

1 stop6h 40mSouthwest

Deal found 12/20

$270

Sat 1/176:00 amIAD - STL

1 stop5h 41mUnited Airlines

Mon 1/1912:44 pmSTL - IAD

Nonstop2h 11mUnited Airlines

Deal found 12/20

$271

Thu 2/127:20 amDCA - STL

Nonstop2h 42mAmerican Airlines

Mon 2/166:00 amSTL - DCA

Nonstop2h 14mAmerican Airlines

Deal found 12/21

$295

Sun 2/110:45 pmPHL - STL

1 stop11h 36mMultiple Airlines

Wed 2/48:22 pmSTL - PHL

2 stops19h 27mMultiple Airlines

Deal found 12/22

$160

Thu 1/2211:09 amPHL - STL

1 stop13h 24mFrontier

Mon 1/2610:16 amSTL - PHL

1 stop5h 58mFrontier

Deal found 12/22

$162

Wed 2/255:00 amEWR - MCI

1 stop11h 29mSpirit Airlines

Sun 3/111:26 amMCI - EWR

1 stop11h 32mSpirit Airlines

Deal found 12/22

$200

Thu 1/83:56 pmPHL - STL

1 stop7h 37mFrontier

Fri 1/98:35 amSTL - PHL

1 stop8h 35mFrontier

Deal found 12/22

$197

Mon 1/126:00 pmEWR - STL

1 stop29h 34mMultiple Airlines

Fri 1/168:32 pmSTL - EWR

2 stops14h 10mMultiple Airlines

Deal found 12/20

$207

Tue 1/66:59 pmPHL - STL

1 stop28h 34mFrontier

Sun 1/115:11 pmSTL - PHL

1 stop14h 26mFrontier

Deal found 12/22

$210

Mon 2/1612:30 pmDCA - STL

Nonstop2h 30mSouthwest

Tue 2/179:40 amSTL - DCA

1 stop4h 15mSouthwest

Deal found 12/22

$271

Thu 1/159:57 pmEWR - STL

Nonstop3h 02mUnited Airlines

Sun 1/1811:22 amSTL - EWR

Nonstop2h 36mUnited Airlines

Deal found 12/22

$273

Fri 2/275:00 amEWR - MCI

1 stop11h 29mSpirit Airlines

Mon 3/94:24 pmMCI - EWR

1 stop6h 25mSpirit Airlines

Deal found 12/23

$251

Thu 2/51:00 pmLGA - STL

1 stop5h 50mDelta

Sat 2/71:20 pmSTL - LGA

Nonstop2h 23mDelta

Deal found 12/23

$277

Thu 2/511:09 amPHL - STL

1 stop13h 24mFrontier

Mon 2/910:16 amSTL - PHL

1 stop11h 16mFrontier

Deal found 12/22

$213

Sat 1/175:00 amEWR - MCI

1 stop12h 09mMultiple Airlines

Mon 1/1911:41 amMCI - EWR

1 stop12h 32mMultiple Airlines

Deal found 12/22

$241

Sat 1/178:47 pmPHL - STL

Nonstop2h 57mAmerican Airlines

Tue 1/206:00 amSTL - PHL

Nonstop2h 22mAmerican Airlines

Deal found 12/21

$297

Sat 2/215:05 amIAD - MCI

1 stop6h 45mSouthwest

Wed 2/2511:25 amMCI - IAD

1 stop9h 30mSouthwest

Deal found 12/21

$271

Fri 1/161:05 pmIAD - MCI

Nonstop3h 05mUnited Airlines

Sun 1/1811:29 amMCI - IAD

1 stop5h 06mUnited Airlines

Deal found 12/22

$276

Wed 1/2810:30 amLGA - STL

Nonstop3h 03mDelta

Sun 2/16:35 amSTL - LGA

1 stop4h 24mDelta

Deal found 12/22

$277

Tue 2/175:00 amEWR - MCI

1 stop11h 29mSpirit Airlines

Wed 2/184:24 pmMCI - EWR

1 stop6h 25mSpirit Airlines

Deal found 12/22

$269

Thu 1/156:35 pmDCA - STL

Nonstop2h 30mSouthwest

Sun 1/183:05 pmSTL - DCA

Nonstop2h 00mSouthwest

Deal found 12/22

$272

Sun 5/108:00 amLGA - STL

1 stop5h 54mDelta

Tue 5/126:00 amSTL - LGA

Nonstop2h 27mDelta

Deal found 12/23

$277

Thu 1/85:59 amEWR - MCI

2 stops14h 27mMultiple Airlines

Fri 1/911:26 amMCI - EWR

1 stop8h 48mMultiple Airlines

Deal found 12/22

$254

Fri 1/95:05 amPHL - STL

1 stop10h 43mFrontier

Sun 1/113:43 pmSTL - PHL

1 stop8h 08mFrontier

Deal found 12/22

$232

Sun 2/11:05 pmIAD - MCI

Nonstop3h 05mUnited Airlines

Sat 2/712:35 pmMCI - IAD

Nonstop2h 34mUnited Airlines

Deal found 12/22

$285

Tue 1/207:17 amPHL - STL

1 stop8h 33mAmerican Airlines

Tue 1/276:00 amSTL - PHL

Nonstop2h 22mAmerican Airlines

Deal found 12/21

$317

Last-minute flights from Pennsylvania to Missouri
Discover last-minute flight deals from Pennsylvania to Missouri. Data last updated December 23, 2025 and is based on user searches.

Wed 1/72:54 pmEWR - STL

1 stop8h 39mMultiple Airlines

Wed 1/148:32 pmSTL - EWR

1 stop10h 21mMultiple Airlines

Deal found 12/21

$140

Mon 1/123:56 pmPHL - STL

1 stop7h 37mFrontier

Tue 1/135:11 pmSTL - PHL

1 stop20h 47mFrontier

Deal found 12/21

$133

Mon 1/121:38 pmPHL - STL

1 stop9h 55mFrontier

Wed 1/148:32 pmSTL - PHL

1 stop13h 42mFrontier

Deal found 12/21

$142

Mon 1/125:00 amEWR - MCI

1 stop12h 09mSpirit Airlines

Thu 1/1511:26 amMCI - EWR

1 stop8h 48mSpirit Airlines

Deal found 12/22

$143

Tue 1/206:00 pmEWR - STL

1 stop30h 33mMultiple Airlines

Wed 1/285:42 pmSTL - EWR

1 stop15h 18mMultiple Airlines

Deal found 12/23

$128

Tue 1/206:20 pmPHL - STL

1 stop13h 31mFrontier

Tue 1/275:42 pmSTL - PHL

1 stop15h 55mFrontier

Deal found 12/21

$131

Tue 1/206:20 pmPHL - STL

1 stop13h 31mFrontier

Thu 1/225:42 pmSTL - PHL

1 stop15h 17mFrontier

Deal found 12/21

$139

Wed 1/2111:44 amEWR - STL

1 stop12h 49mMultiple Airlines

Wed 1/288:22 pmSTL - EWR

1 stop10h 31mMultiple Airlines

Deal found 12/22

$132

Wed 1/2111:44 amEWR - STL

1 stop12h 49mMultiple Airlines

Fri 1/2311:18 amSTL - EWR

1 stop11h 09mMultiple Airlines

Deal found 12/22

$133

Thu 1/223:30 pmEWR - STL

1 stop9h 03mMultiple Airlines

Tue 1/275:42 pmSTL - EWR

1 stop16h 07mMultiple Airlines

Deal found 12/23

$142

Thu 1/227:00 amPHL - STL

1 stop28h 23mFrontier

Sat 1/2411:00 amSTL - PHL

1 stop10h 46mFrontier

Deal found 12/20

$145

Fri 1/2310:30 pmEWR - STL

1 stop9h 21mMultiple Airlines

Sun 1/255:42 pmSTL - EWR

1 stop15h 18mMultiple Airlines

Deal found 12/22

$139

One-way flights from Pennsylvania to Missouri
Search for one-way flight options from Pennsylvania to Missouri. Find affordable one-way fares based on user searches. Data last updated December 23, 2025.

Tue 1/205:00 amEWR - MCI

1 stop12h 09mSpirit Airlines

Deal found 12/22

$60

Fri 1/2310:30 pmEWR - STL

1 stop9h 21mFrontier

Deal found 12/21

$60

Wed 2/411:44 amEWR - STL

1 stop12h 49mFrontier

Deal found 12/21

$61

Mon 1/123:30 pmEWR - STL

1 stop8h 03mMultiple Airlines

Deal found 12/21

$62

Tue 1/206:00 pmEWR - STL

1 stop30h 33mMultiple Airlines

Deal found 12/23

$63

Sat 1/248:00 amDCA - STL

1 stop7h 46mFrontier

Deal found 12/21

$64

Sat 2/216:13 pmPHL - STL

1 stop6h 46mFrontier

Deal found 12/21

$64

Wed 2/253:45 pmPHL - STL

1 stop7h 42mFrontier

Deal found 12/22

$65

Sun 1/118:43 pmPHL - STL

1 stop12h 22mMultiple Airlines

Deal found 12/21

$66

Fri 2/610:30 pmEWR - STL

1 stop9h 21mFrontier

Deal found 12/21

$67

Tue 1/206:20 pmPHL - STL

1 stop13h 31mFrontier

Deal found 12/20

$67

Sun 1/118:35 amIAD - STL

1 stop24h 30mFrontier

Deal found 12/21

$68

Find flight deals from Pennsylvania to Missouri

Most accurate provider	Gotogate 3 stars
Most trusted provider	Gotogate 3 stars
Round-trip from	$131 (Kiwi.com)
One-way from	$60 (Kiwi.com)
Popular in	May
Cheapest in	August
Average price	$465
Good round-trip deal	$358 or less
Good one-way deal	$202 or less

Provider with most accurate pricing for Philadelphia-Lambert-St Louis flight deals.

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Provider most trusted by Cheapflights users for Philadelphia-Lambert-St Louis flights.

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From Pennsylvania to Missouri

Search Deals

One-way flight from Pennsylvania to Missouri

Search Deals

Highest demand for flights based on searches. 7% potential increase in price ($34 potential increase over avg. RT price).

Search Deals

Cheapest flight prices on average. 1% potential price decrease ($7 potential savings vs. average RT price).

Search Deals

Average for round-trip flights in December 2025

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Price to beat on a round-trip flight from Pennsylvania to Missouri.

Search Deals

Price to beat on a one-way flight from Pennsylvania to Missouri.

Search Deals

Cheapflights Fare Finder

Use the filters below to find and compare flights from Pennsylvania to Missouri that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

PhiladelphiaSt. Louis

PHL - STL

PHLSTL

Philadelphia

Tue 1/20

6:20 pm-6:51 am

1 stop13h 31m

Lambert-St Louis

Tue 1/27

5:42 pm-10:37 am

1 stop15h 55m

$131

PhiladelphiaSt. Louis

PHL - STL

PHLSTL

Philadelphia

Tue 1/20

2:36 pm-6:51 am

1 stop17h 15m

Lambert-St Louis

Tue 1/27

5:42 pm-3:40 pm

2 stops20h 58m

$158

PhiladelphiaSt. Louis

PHL - STL

PHLSTL

Philadelphia

Sun 2/1

10:45 pm-9:21 am

1 stop11h 36m

Lambert-St Louis

Wed 2/4

8:22 pm-4:49 pm

2 stops19h 27m

$160

PhiladelphiaSt. Louis

PHL - STL

PHLSTL

Philadelphia

Thu 1/22

11:09 am-11:33 pm

1 stop13h 24m

Lambert-St Louis

Mon 1/26

10:16 am-5:14 pm

1 stop5h 58m

$162

NewarkKansas City

EWR - MCI

EWRMCI

Newark

Wed 1/7

5:51 am-5:10 pm

1 stop12h 19m

Kansas City

Mon 1/12

11:26 am-11:42 am

1 stop23h 16m

$185

PhiladelphiaSt. Louis

PHL - STL

PHLSTL

Philadelphia

Thu 1/8

3:56 pm-10:33 pm

1 stop7h 37m

Lambert-St Louis

Fri 1/9

8:35 am-6:10 pm

1 stop8h 35m

$197

NewarkKansas City

EWR - MCI

EWRMCI

Newark

Wed 2/25

5:00 am-3:29 pm

1 stop11h 29m

Kansas City

Sun 3/1

11:26 am-11:58 pm

1 stop11h 32m

$200

NewarkSt. Louis

EWR - STL

EWRSTL

Newark

Mon 1/12

6:00 pm-10:34 pm

1 stop29h 34m

Lambert-St Louis

Fri 1/16

8:32 pm-11:42 am

2 stops14h 10m

$207

PhiladelphiaSt. Louis

PHL - STL

PHLSTL

Philadelphia

Tue 1/6

6:59 pm-10:33 pm

1 stop28h 34m

Lambert-St Louis

Sun 1/11

5:11 pm-8:37 am

1 stop14h 26m

$210

PhiladelphiaSt. Louis

PHL - STL

PHLSTL

Philadelphia

Thu 2/5

11:09 am-11:33 pm

1 stop13h 24m

Lambert-St Louis

Mon 2/9

10:16 am-10:32 pm

1 stop11h 16m

$213

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/22

Showing 1-10 of 60 results

...

Best time to book a flight from Pennsylvania to Missouri

Have a flexible travel schedule? Discover the best time to fly to Missouri from Pennsylvania with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Pennsylvania to Missouri

What is the cheapest month to book a flight from Pennsylvania to Missouri?

Currently, February is the cheapest month in which you can book a flight from Pennsylvania to Missouri (average of $128). Flying from Pennsylvania to Missouri in June is currently the most expensive (average of $229). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from PA to MO?

It’s optimal to fly from Pennsylvania to Missouri in the evening. By choosing this option you can save up to 30% on the cost of your flight, compared to a flight at noon.

What is the cheapest day to fly from Pennsylvania to Missouri?

Travelers seeking maximum savings on their Pennsylvania to Missouri flight should consider departing on Tuesday evenings when fares are most often at their lowest. Sunday mornings flights should be avoided if possible as fares are typically the most expensive at this time.

Reviews of airlines servicing Missouri

Read through reviews of airlines operating flights from Pennsylvania to Missouri, such as Southwest, Delta, and United Airlines. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.

Southwest

8.0

Very good

4,253 reviews

Reviews

1 / 20

2.0

Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

Southwest

8.0

Very good

4,253 reviews

Southwest

8.0

Very good

4,253 reviews

Reviews

1 / 20

2.0

Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

Delta

7.9

Good

8,014 reviews

Southwest

8.0

Very good

4,253 reviews

Reviews

1 / 20

2.0

Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

United Airlines

7.4

Good

9,105 reviews

Southwest

8.0

Very good

4,253 reviews

Reviews

1 / 20

2.0

Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

American Airlines

7.2

Good

11,054 reviews

Southwest

8.0

Very good

4,253 reviews

Reviews

1 / 20

2.0

Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

Frontier

5.8

Fair

3,075 reviews

Southwest

8.0

Very good

4,253 reviews

Reviews

1 / 20

2.0

Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

Related info for your journey

How popular is this Pennsylvania to Missouri flight route?
Flights from Pennsylvania to Missouri have been viewed 41 times in the past calendar month.
How long is the flight from Pennsylvania to Missouri?
A quick flight from Pennsylvania to Missouri can take about 5h 54m. Frontier provides one of the quickest options available for as low as $261. There are 869 mi between Pennsylvania and Missouri. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.
Can I find deals for flights from Pennsylvania to Missouri that include hotel bookings?
Yes. In addition to deals on Pennsylvania to Missouri flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Pennsylvania to Missouri?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Pennsylvania to Missouri.
Can I find deals for business class flights from Pennsylvania to Missouri?
Yes. Cheapflights offers flight deals from Pennsylvania to Missouri by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Pennsylvania to Missouri?
Currently, February is the cheapest month in which you can book a flight from Pennsylvania to Missouri (average of $128). Flying from Pennsylvania to Missouri in June is currently the most expensive (average of $229). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Top 6 airlines flying from Pennsylvania to Missouri

Airline	Cheapest	Average	Flexibility	On-time
Spirit Airlines	Cheapest$95	Average$297	FlexibilityNo cancel fee	On-time65%
Frontier	Cheapest$130	Average$242	FlexibilityNo cancel fee	On-time62%
American Airlines	Cheapest$171	Average$409	FlexibilityNo cancel fee	On-time71%
Delta	Cheapest$214	Average$363	FlexibilityNo cancel fee	On-timeN/A
Southwest	Cheapest$241	Average$410	FlexibilityNo cancel fee	On-time63%
United Airlines	Cheapest$248	Average$411	FlexibilityNo cancel fee	On-time69%

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$60+ Cheap flights from Pennsylvania to Missouri

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/20. Fares are subject to change and may not be available on all flights or dates of travel.

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Cheap flight deals from Pennsylvania to Missouri

Cheapest flights from Pennsylvania to MissouriExplore the most affordable flight options available from Pennsylvania to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 23, 2025.

Explore the most affordable flight options available from Pennsylvania to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 23, 2025.

Find flight deals from Pennsylvania to Missouri

Keep the following information in mind while searching for Pennsylvania to Missouri flight deals. Data was last updated December 23, 2025.

Most accurate provider

Most trusted provider

Round-trip from

One-way from

Popular in

Cheapest in

Average price

Good round-trip deal

Good one-way deal

Cheapflights Fare Finder

Use the filters below to find and compare flights from Pennsylvania to Missouri that are best for you.

Best time to book a flight from Pennsylvania to Missouri

Have a flexible travel schedule? Discover the best time to fly to Missouri from Pennsylvania with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Pennsylvania to Missouri

What is the cheapest month to book a flight from Pennsylvania to Missouri?

What is the cheapest time of day to fly from PA to MO?

Find hourly flight availability from Pennsylvania to Missouri. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 23, 2025.

What is the cheapest day to fly from Pennsylvania to Missouri?

Use this chart to determine the cheapest time to fly round-trip from Pennsylvania to Missouri. Price data was last updated on December 16, 2024.

Reviews of airlines servicing Missouri

Read through reviews of airlines operating flights from Pennsylvania to Missouri, such as Southwest, Delta, and United Airlines. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from Pennsylvania to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

How popular is this Pennsylvania to Missouri flight route?

How long is the flight from Pennsylvania to Missouri?

Can I find deals for flights from Pennsylvania to Missouri that include hotel bookings?

How can I find direct flights from Pennsylvania to Missouri?

Can I find deals for business class flights from Pennsylvania to Missouri?

What is the cheapest month to book a flight from Pennsylvania to Missouri?

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Pennsylvania to Missouri

See prices for flight routes from nearby airports that may be better suited for you.

Top 6 airlines flying from Pennsylvania to Missouri

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Cheapest flights from Pennsylvania to Missouri
Explore the most affordable flight options available from Pennsylvania to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 23, 2025.