$56+ Cheap flights from Pennsylvania to Missouri
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/18. Fares are subject to change and may not be available on all flights or dates of travel.
PHL — STL
Nov 18 — Nov 251
Round-trip
1 adult, Economy
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Find cheap flights from Pennsylvania to Missouri with Cheapflights
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Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Cheapest flights from Pennsylvania to MissouriExplore the most affordable flight options available from Pennsylvania to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 19, 2026.
Explore the most affordable flight options available from Pennsylvania to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 19, 2026.
This Southwest deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/141:10 pm -
Nonstop1h 50m
Sat 11/218:10 pm -
Nonstop1h 40m
Deal found 10/16![Southwest logo]()
$239
This Southwest deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/237:15 pm -
1 stop6h 55m
Tue 12/295:10 am -
1 stop3h 55m
Deal found 10/18![Southwest logo]()
$267
This Trip.com deal was found by Cheapflights users on 10/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/1911:43 am -
1 stop25h 42m
Mon 11/236:05 pm -
1 stop22h 59m
Deal found 10/17![Frontier logo]()
$271
This Southwest deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/228:15 pm -
Nonstop1h 45m
Wed 11/256:25 pm -
1 stop5h 30m
Deal found 10/15![Southwest logo]()
$277
This American Airlines deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/236:40 pm -
Nonstop2h 53m
Thu 11/266:02 am -
Nonstop2h 15m
Deal found 10/14![American Airlines logo]()
$277
This Cheapflightsfares deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/65:45 pm -
1 stop6h 31m
Wed 11/116:34 pm -
1 stop11h 37m
Deal found 10/18![Frontier logo]()
$278
This Southwest deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/133:30 pm -
1 stop5h 45m
Sat 11/1411:30 am -
1 stop5h 30m
Deal found 10/15![Southwest logo]()
$279
This Southwest deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/125:00 am -
1 stop7h 15m
Sun 11/154:30 pm -
1 stop6h 40m
Deal found 10/19![Southwest logo]()
$281
This Southwest deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/46:50 am -
Nonstop1h 55m
Sun 12/67:55 pm -
Nonstop1h 40m
Deal found 10/16![Southwest logo]()
$282
This Expedia deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/610:17 am -
1 stop14h 55m
Mon 12/76:13 pm -
1 stop27h 36m
Deal found 10/14![Frontier logo]()
$282
This Delta deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/35:09 pm -
1 stop5h 29m
Sun 12/67:18 pm -
1 stop4h 28m
Deal found 10/14![Delta logo]()
$283
This Mytrip deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/118:30 am -
2 stops29h 03m
Wed 11/184:18 pm -
2 stops27h 02m
Deal found 10/14![Frontier logo]()
$283
Best flights from Pennsylvania to MissouriDiscover carefully curated flight deals from Pennsylvania to Missouri that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 19, 2026.
Discover carefully curated flight deals from Pennsylvania to Missouri that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 19, 2026.
This Southwest deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/237:15 pm -
1 stop6h 55m
Tue 12/295:10 am -
1 stop3h 55m
Deal found 10/18![Southwest logo]()
$267
This Delta deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/35:09 pm -
1 stop5h 29m
Sun 12/67:18 pm -
1 stop4h 28m
Deal found 10/14![Delta logo]()
$283
This United Airlines deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/136:01 pm -
1 stop4h 39m
Fri 11/207:30 am -
1 stop4h 36m
Deal found 10/16![United Airlines logo]()
$301
This American Airlines deal was found by Cheapflights users on 10/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/53:17 pm -
1 stop4h 49m
Sat 12/126:02 am -
1 stop4h 25m
Deal found 10/17![American Airlines logo]()
$321
This Southwest deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/67:25 pm -
Nonstop2h 35m
Sat 11/710:35 am -
Nonstop2h 10m
Deal found 10/14![Southwest logo]()
$277
This Delta deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/46:00 am -
1 stop6h 29m
Sun 12/65:31 pm -
1 stop6h 15m
Deal found 10/16![Delta logo]()
$292
This Southwest deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/46:50 am -
Nonstop1h 55m
Sun 12/67:55 pm -
Nonstop1h 40m
Deal found 10/16![Southwest logo]()
$282
This American Airlines deal was found by Cheapflights users on 10/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/47:43 am -
1 stop5h 40m
Tue 2/95:57 am -
1 stop6h 55m
Deal found 10/17![American Airlines logo]()
$330
This United Airlines deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/158:15 am -
1 stop4h 55m
Sun 11/227:30 am -
1 stop4h 54m
Deal found 10/16![United Airlines logo]()
$339
This Southwest deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/105:50 am -
1 stop6h 10m
Thu 11/123:35 pm -
1 stop7h 10m
Deal found 10/18![Southwest logo]()
$294
This Delta deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/186:10 am -
1 stop4h 36m
Mon 2/225:40 pm -
1 stop4h 06m
Deal found 10/19![Delta logo]()
$349
This American Airlines deal was found by Cheapflights users on 10/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/12:15 pm -
1 stop6h 13m
Sat 12/51:50 pm -
1 stop7h 38m
Deal found 10/17![American Airlines logo]()
$349
This United Airlines deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/172:10 pm -
1 stop4h 55m
Tue 11/243:10 pm -
1 stop5h 23m
Deal found 10/18![United Airlines logo]()
$349
This Southwest deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/237:05 pm -
1 stop4h 35m
Mon 1/41:25 pm -
2 stops9h 30m
Deal found 10/14![Southwest logo]()
$302
This Delta deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/26:33 pm -
1 stop6h 23m
Sun 12/65:41 pm -
1 stop5h 07m
Deal found 10/14![Delta logo]()
$349
This American Airlines deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/1512:57 pm -
1 stop7h 34m
Mon 1/182:12 pm -
1 stop5h 48m
Deal found 10/18![American Airlines logo]()
$349
This United Airlines deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/128:15 am -
1 stop4h 55m
Thu 11/195:00 am -
1 stop7h 24m
Deal found 10/15![United Airlines logo]()
$351
This Southwest deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/226:35 am -
Nonstop2h 00m
Wed 11/257:55 pm -
Nonstop1h 40m
Deal found 10/15![Southwest logo]()
$310
This Delta deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/166:00 am -
1 stop5h 56m
Sun 12/205:09 pm -
1 stop5h 47m
Deal found 10/15![Delta logo]()
$349
This United Airlines deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/188:15 am -
1 stop5h 08m
Tue 12/16:00 am -
2 stops7h 00m
Deal found 10/18![United Airlines logo]()
$360
This Southwest deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/224:10 pm -
1 stop5h 50m
Mon 12/285:45 am -
1 stop7h 45m
Deal found 10/18![Southwest logo]()
$316
This Delta deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/225:30 am -
1 stop6h 41m
Tue 3/306:00 am -
1 stop6h 03m
Deal found 10/18![Delta logo]()
$349
This American Airlines deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/33:54 pm -
2 stops7h 21m
Sat 11/710:24 am -
1 stop7h 12m
Deal found 10/19![American Airlines logo]()
$394
This United Airlines deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/156:00 am -
1 stop6h 46m
Tue 12/155:00 pm -
1 stop5h 59m
Deal found 10/16![United Airlines logo]()
$364
This Delta deal was found by Cheapflights users on 10/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/208:00 am -
1 stop6h 23m
Sun 11/226:40 am -
1 stop3h 57m
Deal found 10/17![Delta logo]()
$353
This Southwest deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/1312:30 pm -
2 stops9h 30m
Fri 11/204:40 pm -
2 stops6h 25m
Deal found 10/16![Southwest logo]()
$322
This United Airlines deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/66:24 am -
1 stop5h 22m
Sat 1/93:12 pm -
1 stop5h 28m
Deal found 10/14![United Airlines logo]()
$378
This Southwest deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/138:50 pm -
1 stop4h 25m
Sun 11/155:35 am -
1 stop3h 45m
Deal found 10/15![Southwest logo]()
$331
This Delta deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/145:58 pm -
1 stop5h 38m
Sun 12/205:09 pm -
1 stop5h 47m
Deal found 10/15![Delta logo]()
$369
This American Airlines deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/23:44 pm -
1 stop6h 54m
Mon 1/116:50 am -
2 stops7h 01m
Deal found 10/14![American Airlines logo]()
$474
Last-minute flights from Pennsylvania to MissouriDiscover last-minute flight deals from Pennsylvania to Missouri. Data last updated October 19, 2026 and is based on user searches.
Discover last-minute flight deals from Pennsylvania to Missouri. Data last updated October 19, 2026 and is based on user searches.
This Cheapflightsfares deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/65:45 pm -
1 stop6h 31m
Wed 11/116:34 pm -
1 stop11h 37m
Deal found 10/18![Frontier logo]()
$278
This Mytrip deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/118:30 am -
2 stops29h 03m
Wed 11/184:18 pm -
2 stops27h 02m
Deal found 10/14![Frontier logo]()
$283
This Southwest deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/125:00 am -
1 stop7h 15m
Sun 11/154:30 pm -
1 stop6h 40m
Deal found 10/19![Southwest logo]()
$281
This Southwest deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/133:30 pm -
1 stop5h 45m
Sat 11/1411:30 am -
1 stop5h 30m
Deal found 10/15![Southwest logo]()
$279
This Southwest deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/141:10 pm -
Nonstop1h 50m
Sat 11/218:10 pm -
Nonstop1h 40m
Deal found 10/16![Southwest logo]()
$239
This Delta deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/1411:07 am -
1 stop6h 16m
Sat 11/214:39 pm -
1 stop5h 10m
Deal found 10/16![Delta logo]()
$249
This Southwest deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/164:25 pm -
1 stop6h 45m
Mon 11/232:35 pm -
1 stop5h 45m
Deal found 10/18![Southwest logo]()
$288
This Trip.com deal was found by Cheapflights users on 10/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/1911:43 am -
1 stop25h 42m
Sun 11/226:05 pm -
1 stop22h 59m
Deal found 10/17![Frontier logo]()
$271
This Cheapflightsfares deal was found by Cheapflights users on 10/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/1912:36 pm -
1 stop7h 03m
Sun 11/225:15 pm -
1 stop11h 46m
Deal found 10/17![Frontier logo]()
$287
This Southwest deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/228:15 pm -
Nonstop1h 45m
Wed 11/256:25 pm -
1 stop5h 30m
Deal found 10/15![Southwest logo]()
$277
This American Airlines deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/236:40 pm -
Nonstop2h 53m
Thu 11/266:02 am -
Nonstop2h 15m
Deal found 10/14![American Airlines logo]()
$277
This Cheapflightsfares deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/2712:38 pm -
1 stop6h 02m
Sun 11/296:05 pm -
1 stop5h 48m
Deal found 10/15![Frontier logo]()
$285
One-way flights from Pennsylvania to MissouriSearch for one-way flight options from Pennsylvania to Missouri. Find affordable one-way fares based on user searches. Data last updated October 19, 2026.
Search for one-way flight options from Pennsylvania to Missouri. Find affordable one-way fares based on user searches. Data last updated October 19, 2026.
This Cheapflightsfares deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1812:36 pm -
1 stop6h 06m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/14![Frontier logo]()
$56
This Kiwi.com deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/126:00 pm -
1 stop24h 42m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/14![Frontier logo]()
$58
This Kiwi.com deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/154:31 pm -
1 stop19h 46m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/18![Frontier logo]()
$77
This Kiwi.com deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/1712:36 pm -
1 stop30h 06m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/18![Frontier logo]()
$78
This Kiwi.com deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/118:30 am -
1 stop10h 12m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/14![Frontier logo]()
$83
This Super.com deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/2712:38 pm -
1 stop6h 02m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/15![Frontier logo]()
$89
This Southwest deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/186:50 am -
Nonstop1h 55m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/19![Southwest logo]()
$106
This Southwest deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/218:20 pm -
Nonstop1h 50m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/19![Southwest logo]()
$112
This Southwest deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/141:10 pm -
Nonstop1h 50m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/14![Southwest logo]()
$121
This Kiwi.com deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/156:30 am -
2 stops36h 12m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/14![Multiple Airlines logo]()
$125
This Delta deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/116:10 am -
1 stop4h 15m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/14![Delta logo]()
$126
This Kiwi.com deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/177:45 am -
3 stops34h 57m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/14![Multiple Airlines logo]()
$128
Find flight deals from Pennsylvania to Missouri
Keep the following information in mind while searching for Pennsylvania to Missouri flight deals. Data was last updated October 19, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $228 (Southwest) |
One-way from | $56 (Cheapflightsfares) |
Popular in | June |
Cheapest in | September |
Average price | $358 |
Good round-trip deal | $308 or less |
Good one-way deal | $217 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Pennsylvania to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 19, 2026.
Use the filters below to find and compare flights from Pennsylvania to Missouri that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
PittsburghSt. Louis
PIT Pittsburgh - STL Lambert-St Louis
PITSTL
Pittsburgh
Sat 11/21
6:30 am-12:12 pm
1 stop6h 42m
Lambert-St Louis
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$110
Quickest round-trip
PittsburghSt. Louis
PIT Pittsburgh - STL Lambert-St Louis
PITSTL
Pittsburgh
Sat 11/14
1:10 pm-2:00 pm
Nonstop1h 50m
Lambert-St Louis
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$121
PittsburghSt. Louis
PIT Pittsburgh - STL Lambert-St Louis
PITSTL
Pittsburgh
Wed 11/11
6:10 am-9:25 am
1 stop4h 15m
Lambert-St Louis
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$126
PittsburghSt. Louis
PIT Pittsburgh - STL Lambert-St Louis
PITSTL
Pittsburgh
Sat 11/14
10:49 am-2:34 pm
1 stop4h 45m
Lambert-St Louis
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$126
PhiladelphiaSt. Louis
PHL Philadelphia - STL Lambert-St Louis
PHLSTL
Philadelphia
Tue 11/10
2:45 pm-4:20 pm
Nonstop2h 35m
Lambert-St Louis
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$139
PhiladelphiaSt. Louis
PHL Philadelphia - STL Lambert-St Louis
PHLSTL
Philadelphia
Tue 2/2
1:15 pm-2:45 pm
Nonstop2h 30m
Lambert-St Louis
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$139
PittsburghKansas City
PIT Pittsburgh - MCI Kansas City
PITMCI
Pittsburgh
Mon 11/9
6:01 pm-9:51 pm
1 stop4h 50m
Kansas City
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$140
PittsburghKansas City
PIT Pittsburgh - MCI Kansas City
PITMCI
Pittsburgh
Tue 11/10
7:10 pm-10:30 pm
1 stop4h 20m
Kansas City
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$140
PittsburghKansas City
PIT Pittsburgh - MCI Kansas City
PITMCI
Pittsburgh
Thu 12/3
4:00 pm-9:15 pm
1 stop6h 15m
Kansas City
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$141
PhiladelphiaSt. Louis
PHL Philadelphia - STL Lambert-St Louis
PHLSTL
Philadelphia
Tue 2/2
6:15 am-10:08 am
1 stop4h 53m
Lambert-St Louis
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$144
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from Pennsylvania to Missouri
Have a flexible travel schedule? Discover the best time to fly to Missouri from Pennsylvania with our price prediction graph.
PIT-STL
MDT-STL
PIT-MCI
MDT-MCI
PHL-STL
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Pennsylvania to Missouri
USPA-USMO
PIT-STL
MDT-STL
PIT-MCI
MDT-MCI
What is the cheapest month to book a flight from Pennsylvania to Missouri?
Currently, January is the cheapest month in which you can book a flight from Pennsylvania to Missouri (average of $358). Flying from Pennsylvania to Missouri in June is currently the most expensive (average of $492). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from PA to MO?
Find hourly flight availability from Pennsylvania to Missouri. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated October 19, 2026.
It’s optimal to fly from Pennsylvania to Missouri in the afternoon. By choosing this option you can save up to 9% on the cost of your flight, compared to a flight in the morning.
Weekly flight availability from Pennsylvania to Missouri
Explore weekly flight availability from Pennsylvania to Missouri. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated October 19, 2026.
The most flights from USPA to USMO are scheduled on a Sunday (10 on average). You will have fewer flight options on Tuesday, which is when the least amount of flights are scheduled (1 on average).
How much does it cost to fly round-trip from Pennsylvania to Missouri?
Airfare is below average for this route at the moment.
Pennsylvania to Missouri flights typically cost between $298 and $458 in November.The cheapest round-trip price found within the last 5 days was $277 on Southwest (Nov 6-Nov 7).
How far ahead should I book a flight from Pennsylvania to Missouri?
Booking 73 days in advance of your planned departure date is, on average, the best time to get cheap flights from Pennsylvania to Missouri. The general trend is that the closer you book to the departure date, the more expensive your flight will be.
What is the cheapest day to fly from Pennsylvania to Missouri?
Use this chart to determine the cheapest time to fly round-trip from Pennsylvania to Missouri. Price data was last updated on October 17, 2026.
Travelers seeking maximum savings on their Pennsylvania to Missouri flight should consider departing on Thursday at noon when fares are most often at their lowest. Sunday afternoons flights should be avoided if possible as fares are typically the most expensive at this time.
Reviews of airlines servicing Missouri
Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated October 19, 2026.
Read through reviews of airlines operating flights from Pennsylvania to Missouri, such as Southwest,Delta, andUnited Airlines. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Comfort
8.0
Crew
8.6
Boarding
8.1
Overall
7.9
Entertainment
7.5
Food
7.0
Reviews
1 / 20
10.0
ExcellentCourtney,Sep 2026
DEN - STL
Comfort
8.0
Crew
8.6
Boarding
8.1
Overall
7.9
Entertainment
7.5
Food
7.0
Reviews
1 / 20
10.0
ExcellentCourtney,Sep 2026
DEN - STL
Comfort
8.0
Crew
8.6
Boarding
8.1
Overall
7.9
Entertainment
7.5
Food
7.0
Reviews
1 / 20
10.0
ExcellentCourtney,Sep 2026
DEN - STL
Comfort
8.0
Crew
8.6
Boarding
8.1
Overall
7.9
Entertainment
7.5
Food
7.0
Reviews
1 / 20
10.0
ExcellentCourtney,Sep 2026
DEN - STL
Comfort
8.0
Crew
8.6
Boarding
8.1
Overall
7.9
Entertainment
7.5
Food
7.0
Reviews
1 / 20
10.0
ExcellentCourtney,Sep 2026
DEN - STL
Comfort
8.0
Crew
8.6
Boarding
8.1
Overall
7.9
Entertainment
7.5
Food
7.0
Reviews
1 / 20
10.0
ExcellentCourtney,Sep 2026
DEN - STL
Related info for your journey
Find useful and relevant information for your journey from Pennsylvania to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Pennsylvania to Missouri
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Missouri by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Pennsylvania to Missouri by cabin class
Find flights from Pennsylvania to Missouri, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Pennsylvania and Missouri flights
Browse other Pennsylvania and Missouri flight options. Last updated on October 19, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Find a return flight route from Missouri
Find the right flight back to Pennsylvania after your stay in Missouri
Pennsylvania to Missouri flights
Consider these flights traveling from Pennsylvania to Missouri.
Top 6 airlines flying from Pennsylvania to Missouri
Discover the top 6 airlines that operate flights from Pennsylvania to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 19, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$142 | Average$246 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$170 | Average$457 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$188 | Average$397 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$217 | Average$430 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$258 | Average$421 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$358 | Average$433 | FlexibilityNo cancel fee | On-time62% |