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Missouri

$277+ Cheap flights from Panama to Missouri

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/27. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — STL
Jun 17 — Jun 241
Tue 6/17
Tue 6/24
1 adult, Economy
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Cheap flight deals from Panama to Missouri

Keep the following information in mind while searching for Panama to Missouri flight deals. Data was last updated June 12, 2025.

Round-trip from

$418
(United Airlines)

One-way from

$281
(Kiwi.com)

Popular in

September

Cheapest in

April

Average price

$649
From Panama to Missouri
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One-way flight from Panama to Missouri
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Highest demand for flights based on searches. 5% potential increase in price ($32 potential increase over avg. RT price).
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Cheapest flight prices on average. 1% potential price decrease ($8 potential savings vs. average RT price).
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Average for round-trip flights in June 2025
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Find flight deals from Panama to Missouri

Cheapest flights from Panama to Missouri
Explore the most affordable flight options available from Panama to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 12, 2025.

This United Airlines deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/110:00 amPTY - MCI
1 stop12h 27mUnited Airlines
Mon 10/66:27 pmMCI - PTY
2 stops19h 47mUnited Airlines
Deal found 6/10$342
This Delta deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/152:05 pmPTY - MCI
1 stop26h 42mDelta
Tue 8/194:11 pmMCI - PTY
1 stop20h 39mDelta
Deal found 6/10$437
This American Airlines deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/263:34 pmPTY - MCI
1 stop8h 25mAmerican Airlines
Sun 10/55:06 amMCI - PTY
1 stop9h 25mAmerican Airlines
Deal found 6/10$446
This Delta deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/272:05 pmPTY - STL
1 stop26h 01mDelta
Tue 9/96:00 amSTL - PTY
1 stop6h 50mDelta
Deal found 6/11$515
This American Airlines deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/273:30 pmPTY - STL
1 stop8h 29mAmerican Airlines
Fri 9/55:28 amSTL - PTY
1 stop9h 03mAmerican Airlines
Deal found 6/11$525
This United Airlines deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/223:30 pmPTY - STL
2 stops19h 10mUnited Airlines
Thu 9/116:15 amSTL - PTY
1 stop7h 59mUnited Airlines
Deal found 6/10$537
This Delta deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/38:10 amPTY - SGF
1 stop10h 01mDelta
Wed 8/136:00 amSGF - PTY
1 stop6h 50mDelta
Deal found 6/9$592
This Mytrip deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/163:20 amPTY - MCI
3 stops37h 49mMultiple Airlines
Sun 8/176:43 pmMCI - PTY
3 stops30h 02mMultiple Airlines
Deal found 6/10$667
This Copa Airlines deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/139:13 amPTY - MCI
1 stop11h 18mCopa Airlines
Fri 6/208:00 amMCI - PTY
1 stop12h 35mCopa Airlines
Deal found 6/10$704
This Mytrip deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/178:10 pmPTY - STL
3 stops23h 50mMultiple Airlines
Sun 12/211:00 pmSTL - PTY
3 stops34h 20mMultiple Airlines
Deal found 6/10$1,410
This Avianca deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/263:20 amPTY - STL
2 stops16h 07mAvianca
Fri 9/58:15 amSTL - PTY
2 stops16h 30mAvianca
Deal found 6/10$3,312

Cheapflights Fare Finder

Customize your flight search to find flights from Panama to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 12, 2025.
Use the filters below to find and compare flights from Panama to Missouri that are best for you.

Fly from

Panama

Fly to

Missouri

Route

Depart

Return

Price

Panama CityKansas City

PTY - MCI

PTYMCI

Panama City Tocumen Intl

Wed 10/1

10:00 am-10:27 pm

1 stop12h 27m

Kansas City

Mon 10/6

6:27 pm-2:14 pm

2 stops19h 47m

$342

Panama CityKansas City

PTY - MCI

PTYMCI

Panama City Tocumen Intl

Fri 8/15

2:05 pm-4:47 pm

1 stop26h 42m

Kansas City

Tue 8/19

4:11 pm-12:50 pm

1 stop20h 39m

$437

Panama CityKansas City

PTY - MCI

PTYMCI

Panama City Tocumen Intl

Fri 9/26

3:34 pm-11:59 pm

1 stop8h 25m

Kansas City

Sun 10/5

5:06 am-2:31 pm

1 stop9h 25m

$446

Panama CitySt. Louis

PTY - STL

PTYSTL

Panama City Tocumen Intl

Wed 8/27

2:05 pm-4:06 pm

1 stop26h 01m

Lambert-St Louis

Wed 9/10

5:11 pm-12:49 pm

1 stop19h 38m

$515

Panama CitySt. Louis

PTY - STL

PTYSTL

Panama City Tocumen Intl

Wed 8/27

3:30 pm-11:59 pm

1 stop8h 29m

Lambert-St Louis

Fri 9/5

5:28 am-2:31 pm

1 stop9h 03m

$525

Panama CitySt. Louis

PTY - STL

PTYSTL

Panama City Tocumen Intl

Fri 8/22

3:30 pm-10:40 am

2 stops19h 10m

Lambert-St Louis

Thu 9/11

6:15 am-2:14 pm

1 stop7h 59m

$537

Panama CitySpringfield

PTY - SGF

PTYSGF

Panama City Tocumen Intl

Sun 8/3

8:10 am-6:11 pm

1 stop10h 01m

Springfield-Branson

Wed 8/13

6:00 am-12:50 pm

1 stop6h 50m

$592

Panama CityKansas City

PTY - MCI

PTYMCI

Panama City Tocumen Intl

Wed 7/16

3:20 am-5:09 pm

3 stops37h 49m

Kansas City

Sun 8/17

6:43 pm-12:45 am

3 stops30h 02m

$667

Panama CitySt. Louis

PTY - STL

PTYSTL

Panama City Tocumen Intl

Sun 8/17

8:10 pm-8:00 pm

3 stops23h 50m

Lambert-St Louis

Sun 12/21

1:00 pm-12:20 am

3 stops34h 20m

$1,410

Panama CitySt. Louis

PTY - STL

PTYSTL

Panama City Tocumen Intl

Tue 8/26

3:20 am-7:27 pm

2 stops16h 07m

Lambert-St Louis

Fri 9/5

8:15 am-12:45 am

2 stops16h 30m

$3,312

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/10

Showing 1-10 of 16 results
1
2

Best time to book a flight from Panama to Missouri

Have a flexible travel schedule? Discover the best time to fly to Missouri from Panama with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Panama to Missouri

What is the cheapest month to book a flight from Panama to Missouri?

Currently, August is the cheapest month in which you can book a flight from Panama to Missouri (average of $311). Flying from Panama to Missouri in March is currently the most expensive (average of $356). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from PA to MO?

Find hourly flight availability from Panama to Missouri. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated June 12, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Panama to Missouri as you normally would.

Rainfall in Missouri by month

Plan your trip to Missouri by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Missouri ranges from 1.1 - 5.2 inches per month. May is typically the wettest month, when rainfall can reach 5.2 in. January is typically the driest time to visit Missouri when rainfall is around 1.1 in.

Temperature in Missouri by month

Plan your trip to Missouri by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Missouri, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 78.8 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 28.4 F).

Reviews of airlines servicing Missouri

Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated June 12, 2025.
Read through reviews of airlines operating flights from Panama to Missouri, such as Delta, United Airlines and American Airlines. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,950 reviews

Entertainment

7.9

Boarding

8.2

Comfort

7.9

Food

7.3

Overall

8.0

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Delta
8.0
Very good
7,950 reviews
Delta
8.0
Very good
7,950 reviews

Entertainment

7.9

Boarding

8.2

Comfort

7.9

Food

7.3

Overall

8.0

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
United Airlines
7.4
Good
8,790 reviews
Delta
8.0
Very good
7,950 reviews

Entertainment

7.9

Boarding

8.2

Comfort

7.9

Food

7.3

Overall

8.0

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,950 reviews

Entertainment

7.9

Boarding

8.2

Comfort

7.9

Food

7.3

Overall

8.0

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Avianca
6.7
Okay
2,345 reviews
Delta
8.0
Very good
7,950 reviews

Entertainment

7.9

Boarding

8.2

Comfort

7.9

Food

7.3

Overall

8.0

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

Find useful and relevant information for your journey from Panama to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • Can I find deals for flights from Panama to Missouri that include hotel bookings?

    Yes. In addition to deals on Panama to Missouri flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Panama to Missouri?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama to Missouri.

  • Can I find deals for business class flights from Panama to Missouri?

    Yes. Cheapflights offers flight deals from Panama to Missouri by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Panama to Missouri?

    Currently, August is the cheapest month in which you can book a flight from Panama to Missouri (average of $311). Flying from Panama to Missouri in March is currently the most expensive (average of $356). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Panama to Missouri

See prices for flight routes from nearby airports that may be better suited for you.
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Top 2 airlines flying from Panama to Missouri

Discover the top 2 airlines that operate flights from Panama to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 12, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$354Average$558FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$420Average$556FlexibilityNo cancel feeOn-time69%

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