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$279+ Cheap flights from Odessa, TX to Missouri

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/27. Fares are subject to change and may not be available on all flights or dates of travel.
MAF — STL
Feb 11 — Feb 181
Wed 2/11
Wed 2/18
1 adult, Economy
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Cheap flight deals from Odessa to Missouri

Keep the following information in mind while searching for Odessa to Missouri flight deals. Data was last updated January 12, 2026.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$279
(American Airlines)
Provider with most accurate pricing for Midland Intl-Lambert-St Louis flight deals.
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Provider most trusted by Cheapflights users for Midland Intl-Lambert-St Louis flights.
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From Odessa to Missouri
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Find flight deals from Odessa to Missouri

Cheapest flights from Odessa to Missouri
Explore the most affordable flight options available from Odessa to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 12, 2026.

This American Airlines deal was found by Cheapflights users on 1/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/278:19 am
MAF
-
SGF
1 stop3h 55m
American Airlines
Sat 1/3110:50 am
SGF
-
MAF
1 stop5h 35m
American Airlines
Deal found 1/12$279
This United Airlines deal was found by Cheapflights users on 1/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/37:00 am
MAF
-
SGF
1 stop6h 58m
United Airlines
Sat 2/78:50 am
SGF
-
MAF
1 stop7h 31m
United Airlines
Deal found 1/11$361
This United Airlines deal was found by Cheapflights users on 1/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/235:35 pm
MAF
-
SGF
1 stop4h 09m
United Airlines
Mon 1/263:00 pm
SGF
-
MAF
1 stop6h 54m
United Airlines
Deal found 1/11$363
This American Airlines deal was found by Cheapflights users on 1/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/165:00 am
MAF
-
SGF
1 stop5h 20m
American Airlines
Mon 1/196:34 pm
SGF
-
MAF
1 stop4h 20m
American Airlines
Deal found 1/11$425
This United Airlines deal was found by Cheapflights users on 1/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/161:45 pm
MAF
-
SGF
1 stop6h 51m
United Airlines
Mon 1/193:14 pm
SGF
-
MAF
2 stops27h 05m
United Airlines
Deal found 1/11$826

Cheapflights Fare Finder

 
Customize your flight search to find flights from Odessa to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 12, 2026.
Use the filters below to find and compare flights from Odessa to Missouri that are best for you.

Fly from

Odessa

Fly to

Missouri

Route

Depart

Return

Price

MidlandSpringfield

MAF - SGF

MAFSGF

Midland Intl

Tue 1/27

6:00 am-10:20 am

1 stop4h 20m

Springfield-Branson

Sat 1/31

1:13 pm-10:54 pm

2 stops9h 41m

$284

MidlandSpringfield

MAF - SGF

MAFSGF

Midland Intl

Tue 2/3

1:45 pm-8:36 pm

1 stop6h 51m

Springfield-Branson

Sat 2/7

8:50 am-4:21 pm

1 stop7h 31m

$361

MidlandSpringfield

MAF - SGF

MAFSGF

Midland Intl

Fri 1/23

5:35 pm-9:44 pm

1 stop4h 09m

Springfield-Branson

Mon 1/26

3:00 pm-9:54 pm

1 stop6h 54m

$363

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/12

Best time to book a flight from Odessa to Missouri

Have a flexible travel schedule? Discover the best time to fly to Missouri from Odessa with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Odessa to Missouri
No data available for this route at this time. Please check back soon.

Reviews of airlines servicing Missouri

Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated January 12, 2026.
See what other customers who have flown with Southwest and American Airlines from Odessa to Missouri have to say. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,253 reviews

Entertainment

7.5

Food

7.0

Crew

8.6

Boarding

8.1

Overall

8.0

Comfort

8.0

Reviews

1 / 20
8.0
Excellent

Ila,Mar 2025

HOU - DAL

Our original flight was delayed. We were able to change our flight and got home at close to the same time. Looking forward to when you have assigned seating.
Southwest
8.0
Very good
4,253 reviews
Southwest
8.0
Very good
4,253 reviews

Entertainment

7.5

Food

7.0

Crew

8.6

Boarding

8.1

Overall

8.0

Comfort

8.0

Reviews

1 / 20
8.0
Excellent

Ila,Mar 2025

HOU - DAL

Our original flight was delayed. We were able to change our flight and got home at close to the same time. Looking forward to when you have assigned seating.
American Airlines
7.2
Good
11,108 reviews
Southwest
8.0
Very good
4,253 reviews

Entertainment

7.5

Food

7.0

Crew

8.6

Boarding

8.1

Overall

8.0

Comfort

8.0

Reviews

1 / 20
8.0
Excellent

Ila,Mar 2025

HOU - DAL

Our original flight was delayed. We were able to change our flight and got home at close to the same time. Looking forward to when you have assigned seating.

Related info for your journey

Find useful and relevant information for your journey from Odessa to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Odessa to Missouri?

    American Airlines and United Airlines can get you from Odessa to Missouri in just under 4h 20m. Your travel time can differ by up to 2h 31m. Airlines will cover a distance of 620 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • Can I find deals for flights from Odessa to Missouri that include hotel bookings?

    Yes. In addition to deals on Odessa to Missouri flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Odessa to Missouri?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Odessa to Missouri.

  • Can I find deals for business class flights from Odessa to Missouri?

    Yes. Cheapflights offers flight deals from Odessa to Missouri by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

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Top 2 airlines flying from Odessa to Missouri

Discover the top 2 airlines that operate flights from Odessa to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 12, 2026.
AirlineCheapestAverageFlexibilityOn-time
SouthwestCheapest$196Average$408FlexibilityNo cancel feeOn-time63%
American AirlinesCheapest$323Average$377FlexibilityNo cancel feeOn-time71%

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