HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Missouri

$399+ Cheap flights from Odessa, TX to Missouri

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/22. Fares are subject to change and may not be available on all flights or dates of travel.
MAF — STL
Apr 19 — Apr 261
Sun 4/19
Sun 4/26
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Odessa to Missouri with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Odessa to Missouri

Cheapest flights from Odessa to Missouri
Explore the most affordable flight options available from Odessa to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 20, 2026.

This United Airlines deal was found by Cheapflights users on 3/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/227:00 am
MAF
-
SGF
1 stop7h 16m
United Airlines
Wed 8/266:15 am
SGF
-
MAF
1 stop7h 17m
United Airlines
Deal found 3/15$399
This United Airlines deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/31:45 pm
MAF
-
SGF
1 stop7h 16m
United Airlines
Tue 4/72:52 pm
SGF
-
MAF
1 stop6h 47m
United Airlines
Deal found 3/19$440
This United Airlines deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/2511:51 am
MAF
-
SGF
2 stops10h 07m
United Airlines
Sat 8/293:05 pm
SGF
-
MAF
1 stop6h 22m
United Airlines
Deal found 3/19$722

Find flight deals from Odessa to Missouri

Keep the following information in mind while searching for Odessa to Missouri flight deals. Data was last updated March 20, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$399
(United Airlines)
Provider with most accurate pricing for Midland Intl-Lambert-St Louis flight deals.
Search Deals
Provider most trusted by Cheapflights users for Midland Intl-Lambert-St Louis flights.
Search Deals
From Odessa to Missouri
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Odessa to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 20, 2026.
Use the filters below to find and compare flights from Odessa to Missouri that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

MidlandSpringfield

MAF - SGF

MAFSGF

Midland Intl

Sat 8/22

7:00 am-2:16 pm

1 stop7h 16m

Springfield-Branson

Wed 8/26

6:15 am-1:32 pm

1 stop7h 17m

$399
Quickest round-trip

MidlandSpringfield

MAF - SGF

MAFSGF

Midland Intl

Tue 8/25

9:31 am-4:21 pm

1 stop6h 50m

Springfield-Branson

Sat 8/29

6:15 am-1:32 pm

1 stop7h 17m

$409

MidlandSpringfield

MAF - SGF

MAFSGF

Midland Intl

Fri 4/3

1:45 pm-9:01 pm

1 stop7h 16m

Springfield-Branson

Tue 4/7

1:33 pm-1:32 pm

2 stops23h 59m

$679

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/15

Sorted by cheapest first

Best time to book a flight from Odessa to Missouri

Have a flexible travel schedule? Discover the best time to fly to Missouri from Odessa with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Odessa to Missouri
No data available for this route at this time. Please check back soon.

Reviews of airlines servicing Missouri

Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated March 20, 2026.
See what other customers who have flown with Southwest and American Airlines from Odessa to Missouri have to say. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,324 reviews

Crew

8.6

Comfort

8.0

Overall

8.0

Entertainment

7.5

Boarding

8.1

Food

7.0

Reviews

1 / 20
6.0
Good

Scott,Feb 2026

HOU - FLL

Delayed by 45 minutes leaving Houston, making a 3.5 hour layover that much longer.
Southwest
8.0
Very good
4,324 reviews
Southwest
8.0
Very good
4,324 reviews

Crew

8.6

Comfort

8.0

Overall

8.0

Entertainment

7.5

Boarding

8.1

Food

7.0

Reviews

1 / 20
6.0
Good

Scott,Feb 2026

HOU - FLL

Delayed by 45 minutes leaving Houston, making a 3.5 hour layover that much longer.
American Airlines
7.1
Good
11,481 reviews
Southwest
8.0
Very good
4,324 reviews

Crew

8.6

Comfort

8.0

Overall

8.0

Entertainment

7.5

Boarding

8.1

Food

7.0

Reviews

1 / 20
6.0
Good

Scott,Feb 2026

HOU - FLL

Delayed by 45 minutes leaving Houston, making a 3.5 hour layover that much longer.

Related info for your journey

Find useful and relevant information for your journey from Odessa to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Odessa to Missouri?

    United Airlines can get you from Odessa to Missouri in just under 7h 16m. Your travel time can differ by up to . Airlines will cover a distance of 620 mi.

  • Can I find deals for flights from Odessa to Missouri that include hotel bookings?

    Yes. In addition to deals on Odessa to Missouri flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Odessa to Missouri?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Odessa to Missouri.

  • Can I find deals for business class flights from Odessa to Missouri?

    Yes. Cheapflights offers flight deals from Odessa to Missouri by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Odessa to Missouri

See prices for flight routes from nearby airports that may be better suited for you.
Dallas/Fort Worth to LaGuardia flights
Dallas/Fort Worth to Las Vegas flights
Dallas/Fort Worth to Seattle flights
Dallas/Fort Worth to John F Kennedy Intl flights
Dallas/Fort Worth to Newark flights
Dallas/Fort Worth to Orlando flights
Dallas/Fort Worth to Los Angeles flights
Dallas/Fort Worth to O'Hare Intl flights
Dallas/Fort Worth to Denver flights
Hobby to Seattle flights
Dallas/Fort Worth to Dulles Intl flights
Dallas/Fort Worth to San Francisco flights
Hobby to LaGuardia flights
Dallas/Fort Worth to Sky Harbor Intl flights
Dallas/Fort Worth to Baltimore flights
Hobby to John F Kennedy Intl flights
Dallas/Fort Worth to Miami flights
Hobby to Las Vegas flights
Dallas/Fort Worth to Fort Lauderdale flights
Dallas/Fort Worth to Ontario flights
Dallas/Fort Worth to Boston flights
Austin to Las Vegas flights
George Bush Intcntl to Seattle flights
Dallas/Fort Worth to Midway flights
Hobby to Los Angeles flights
Dallas/Fort Worth to San Diego flights
George Bush Intcntl to John F Kennedy Intl flights
Hobby to Orlando flights
George Bush Intcntl to Las Vegas flights
Dallas/Fort Worth to Reagan-National flights
Hobby to Miami flights
George Bush Intcntl to Newark flights
Hobby to Newark flights
Dallas/Fort Worth to Atlanta flights
San Antonio to Las Vegas flights
Austin to John F Kennedy Intl flights
George Bush Intcntl to LaGuardia flights
George Bush Intcntl to Los Angeles flights
Hobby to Denver flights
Austin to Seattle flights
Austin to Los Angeles flights
Dallas/Fort Worth to Burbank flights
Dallas/Fort Worth to Santa Ana flights
Love Field to Las Vegas flights
Austin to O'Hare Intl flights
Dallas/Fort Worth to Philadelphia flights
Austin to Newark flights
Dallas/Fort Worth to Salt Lake City flights
Hobby to Dulles Intl flights
George Bush Intcntl to O'Hare Intl flights

Top 2 airlines flying from Odessa to Missouri

Discover the top 2 airlines that operate flights from Odessa to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 20, 2026.
AirlineCheapestAverageFlexibilityOn-time
SouthwestCheapest$196Average$361FlexibilityNo cancel feeOn-time63%
American AirlinesCheapest$323Average$377FlexibilityNo cancel feeOn-time71%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.