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$369+ Cheap flights from Odessa, TX to Missouri

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/20. Fares are subject to change and may not be available on all flights or dates of travel.
MAF — STL
Dec 17 — Dec 241
Wed 12/17
Wed 12/24
1 adult, Economy
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Find flight deals from Odessa to Missouri

Cheapest flights from Odessa to Missouri
Explore the most affordable flight options available from Odessa to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 17, 2025.

This American Airlines deal was found by Cheapflights users on 11/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/208:28 pmMAF - SGF
1 stop3h 26mAmerican Airlines
Sat 11/222:16 pmSGF - MAF
1 stop3h 46mAmerican Airlines
Deal found 11/16$369
This United Airlines deal was found by Cheapflights users on 11/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/201:55 pmMAF - SGF
2 stops7h 51mUnited Airlines
Sat 11/225:07 pmSGF - MAF
1 stop4h 56mUnited Airlines
Deal found 11/16$906

Cheap flight deals from Odessa to Missouri

Keep the following information in mind while searching for Odessa to Missouri flight deals. Data was last updated November 17, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$463
(American Airlines)

Popular in

July

Cheapest in

September

Average price

$283
Provider with most accurate pricing for Midland Intl-Lambert-St Louis flight deals.
Search Deals
Provider most trusted by Cheapflights users for Midland Intl-Lambert-St Louis flights.
Search Deals
From Odessa to Missouri
Search Deals
Highest demand for flights based on searches. 11% potential increase in price ($46 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 7% potential price decrease ($24 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in November 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Odessa to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 17, 2025.
Use the filters below to find and compare flights from Odessa to Missouri that are best for you.

Fly from

Odessa

Fly to

Missouri

Route

Depart

Return

Price

MidlandSpringfield

MAF - SGF

MAFSGF

Midland Intl

Wed 3/4

10:20 am-1:53 pm

1 stop3h 33m

Springfield-Branson

Sat 3/7

8:24 am-1:52 pm

1 stop5h 28m

$463

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/15

Best time to book a flight from Odessa to Missouri

Have a flexible travel schedule? Discover the best time to fly to Missouri from Odessa with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Odessa to Missouri

What is the cheapest time of day to fly from OD3 to MO?

Find hourly flight availability from Odessa to Missouri. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated November 17, 2025.

Unlike at noon, when flights are generally more expensive, you can save up to 59% on flights from Odessa to Missouri by exploring options for tickets in the evening.

Reviews of airlines servicing Missouri

Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated November 17, 2025.
See what other customers who have flown with Southwest and American Airlines from Odessa to Missouri have to say. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,245 reviews

Food

7.0

Boarding

8.1

Overall

8.0

Comfort

8.0

Crew

8.6

Entertainment

7.5

Reviews

1 / 20
8.0
Excellent

Ila,Mar 2025

HOU - DAL

Our original flight was delayed. We were able to change our flight and got home at close to the same time. Looking forward to when you have assigned seating.
Southwest
8.0
Very good
4,245 reviews
Southwest
8.0
Very good
4,245 reviews

Food

7.0

Boarding

8.1

Overall

8.0

Comfort

8.0

Crew

8.6

Entertainment

7.5

Reviews

1 / 20
8.0
Excellent

Ila,Mar 2025

HOU - DAL

Our original flight was delayed. We were able to change our flight and got home at close to the same time. Looking forward to when you have assigned seating.
American Airlines
7.2
Good
11,048 reviews
Southwest
8.0
Very good
4,245 reviews

Food

7.0

Boarding

8.1

Overall

8.0

Comfort

8.0

Crew

8.6

Entertainment

7.5

Reviews

1 / 20
8.0
Excellent

Ila,Mar 2025

HOU - DAL

Our original flight was delayed. We were able to change our flight and got home at close to the same time. Looking forward to when you have assigned seating.

Related info for your journey

Find useful and relevant information for your journey from Odessa to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Odessa to Missouri?

    American Airlines can get you from Odessa to Missouri in just under 3h 33m. Your travel time can differ by up to . Airlines will cover a distance of 620 mi.

  • Can I find deals for flights from Odessa to Missouri that include hotel bookings?

    Yes. In addition to deals on Odessa to Missouri flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Odessa to Missouri?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Odessa to Missouri.

  • Can I find deals for business class flights from Odessa to Missouri?

    Yes. Cheapflights offers flight deals from Odessa to Missouri by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

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Top 2 airlines flying from Odessa to Missouri

Discover the top 2 airlines that operate flights from Odessa to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 17, 2025.
AirlineCheapestAverageFlexibilityOn-time
SouthwestCheapest$196Average$376FlexibilityNo cancel feeOn-time63%
American AirlinesCheapest$323Average$438FlexibilityNo cancel feeOn-time71%

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