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$98+ Cheap flights from Myrtle Beach (MYR) to Missouri

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/10. Fares are subject to change and may not be available on all flights or dates of travel.
MYR — STL
Dec 10 — Dec 171
Wed 12/10
Wed 12/17
1 adult, Economy
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Cheap flight deals from Myrtle Beach to Missouri

Keep the following information in mind while searching for Myrtle Beach to Missouri flight deals. Data was last updated November 10, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$240
(Kiwi.com)

One-way from

$98
(Kiwi.com)

Popular in

February

Cheapest in

August

Average price

$411
Provider with most accurate pricing for Myrtle Beach Intl-Lambert-St Louis flight deals.
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Provider most trusted by Cheapflights users for Myrtle Beach Intl-Lambert-St Louis flights.
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From Myrtle Beach Intl to Missouri
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One-way flight from Myrtle Beach Intl to Missouri
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Highest demand for flights based on searches. 6% potential increase in price ($26 potential increase over avg. RT price).
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Cheapest flight prices on average. 1% potential price decrease ($4 potential savings vs. average RT price).
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Average for round-trip flights in November 2025
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Find flight deals from Myrtle Beach to Missouri

Cheapest flights from Myrtle Beach to Missouri
Explore the most affordable flight options available from Myrtle Beach to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 10, 2025.

This Kiwi.com deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/59:54 amMYR - MCI
1 stop9h 02mSpirit Airlines
Mon 12/87:01 pmMCI - MYR
1 stop21h 47mSpirit Airlines
Deal found 11/9$240
This American Airlines deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/33:29 pmMYR - SGF
1 stop6h 25mAmerican Airlines
Sat 12/66:34 pmSGF - MYR
1 stop4h 20mAmerican Airlines
Deal found 11/9$249
This Kiwi.com deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/189:54 amMYR - MCI
1 stop8h 16mSpirit Airlines
Mon 12/226:15 pmMCI - MYR
1 stop22h 53mSpirit Airlines
Deal found 11/9$288
This Kiwi.com deal was found by Cheapflights users on 11/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/22:46 pmMYR - MCI
1 stop28h 50mSpirit Airlines
Thu 12/43:47 pmMCI - MYR
2 stops15h 13mSpirit Airlines
Deal found 11/10$303
This American Airlines deal was found by Cheapflights users on 11/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/205:21 pmMYR - SGF
1 stop6h 07mAmerican Airlines
Mon 11/245:35 pmSGF - MYR
1 stop4h 01mAmerican Airlines
Deal found 11/8$309
This Kiwi.com deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/189:54 amMYR - MCI
2 stops25h 14mMultiple Airlines
Mon 12/226:15 pmMCI - MYR
1 stop22h 53mMultiple Airlines
Deal found 11/9$320
This American Airlines deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/123:32 pmMYR - SGF
1 stop6h 16mAmerican Airlines
Wed 11/199:25 amSGF - MYR
1 stop6h 16mAmerican Airlines
Deal found 11/9$354
This Delta deal was found by Cheapflights users on 11/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/210:32 amMYR - MCI
1 stop6h 34mDelta
Thu 12/46:38 pmMCI - MYR
1 stop4h 05mDelta
Deal found 11/10$357
This American Airlines deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/121:54 pmMYR - SGF
2 stops7h 53mAmerican Airlines
Sun 11/164:28 pmSGF - MYR
1 stop4h 37mAmerican Airlines
Deal found 11/9$359
This Mytrip deal was found by Cheapflights users on 11/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/136:15 amMYR - MCI
1 stop7h 13mSpirit Airlines
Mon 11/177:33 pmMCI - MYR
2 stops17h 18mSpirit Airlines
Deal found 11/10$361
This Delta deal was found by Cheapflights users on 11/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/186:56 pmMYR - STL
1 stop4h 01mDelta
Sat 1/37:10 amSTL - MYR
1 stop8h 24mDelta
Deal found 11/10$387
This American Airlines deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/185:11 pmMYR - STL
1 stop6h 45mAmerican Airlines
Sat 1/32:08 pmSTL - MYR
2 stops8h 47mAmerican Airlines
Deal found 11/9$397

Cheapflights Fare Finder

 
Customize your flight search to find flights from Myrtle Beach to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 10, 2025.
Use the filters below to find and compare flights from Myrtle Beach to Missouri that are best for you.

Fly from

Myrtle Beach

Fly to

Missouri

Route

Depart

Return

Price

Myrtle BeachKansas City

MYR - MCI

MYRMCI

Myrtle Beach Intl

Fri 12/5

9:54 am-5:56 pm

1 stop9h 02m

Kansas City

Mon 12/8

7:01 pm-5:48 pm

1 stop21h 47m

$240

Myrtle BeachSpringfield

MYR - SGF

MYRSGF

Myrtle Beach Intl

Wed 12/3

3:29 pm-8:54 pm

1 stop6h 25m

Springfield-Branson

Sat 12/6

6:34 pm-11:54 pm

1 stop4h 20m

$249

Myrtle BeachKansas City

MYR - MCI

MYRMCI

Myrtle Beach Intl

Thu 12/18

9:54 am-5:10 pm

1 stop8h 16m

Kansas City

Mon 12/22

6:15 pm-6:08 pm

1 stop22h 53m

$288

Myrtle BeachKansas City

MYR - MCI

MYRMCI

Myrtle Beach Intl

Tue 12/2

2:46 pm-6:36 pm

1 stop28h 50m

Kansas City

Thu 12/4

3:47 pm-8:00 am

2 stops15h 13m

$303

Myrtle BeachSpringfield

MYR - SGF

MYRSGF

Myrtle Beach Intl

Thu 11/27

4:45 pm-10:13 pm

1 stop6h 28m

Springfield-Branson

Thu 12/4

6:49 pm-11:43 pm

1 stop3h 54m

$309

Myrtle BeachSpringfield

MYR - SGF

MYRSGF

Myrtle Beach Intl

Fri 11/21

10:35 am-3:17 pm

1 stop5h 42m

Springfield-Branson

Mon 11/24

4:02 pm-11:44 pm

1 stop6h 42m

$309

Myrtle BeachSpringfield

MYR - SGF

MYRSGF

Myrtle Beach Intl

Thu 11/20

5:21 pm-10:28 pm

1 stop6h 07m

Springfield-Branson

Mon 11/24

5:35 pm-10:36 pm

1 stop4h 01m

$309

Myrtle BeachSt. Louis

MYR - STL

MYRSTL

Myrtle Beach Intl

Tue 3/10

6:00 am-9:04 am

1 stop4h 04m

Lambert-St Louis

Wed 3/11

6:00 am-1:29 pm

1 stop6h 29m

$343

Myrtle BeachKansas City

MYR - MCI

MYRMCI

Myrtle Beach Intl

Tue 12/2

10:32 am-4:06 pm

1 stop6h 34m

Kansas City

Thu 12/4

6:38 pm-11:43 pm

1 stop4h 05m

$357

Myrtle BeachKansas City

MYR - MCI

MYRMCI

Myrtle Beach Intl

Thu 11/13

6:15 am-12:28 pm

1 stop7h 13m

Kansas City

Mon 11/17

7:33 pm-1:51 pm

2 stops17h 18m

$361

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/8

Showing 1-10 of 37 results
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Best time to book a flight from Myrtle Beach to Missouri

Have a flexible travel schedule? Discover the best time to fly to Missouri from Myrtle Beach with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Myrtle Beach to Missouri

What is the cheapest month to book a flight from Myrtle Beach to Missouri?

Currently, December is the cheapest month in which you can book a flight from Myrtle Beach to Missouri (average of $118). Flying from Myrtle Beach to Missouri in July is currently the most expensive (average of $248). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MYR to MO?

Find hourly flight availability from Myrtle Beach to Missouri. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated November 10, 2025.

A simple way to save on the total cost of your ticket is to fly from Myrtle Beach to Missouri in the afternoon. If you’re flexible enough to do this you can expect to save up to 31% on your trip compared to booking a flight at noon.

What is the cheapest day to fly from Myrtle Beach to Missouri?

Use this chart to determine the cheapest time to fly round-trip from Myrtle Beach to Missouri. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their Myrtle Beach to Missouri flight should consider departing on Sunday afternoons when fares are most often at their lowest. Sunday at noon flights should be avoided if possible as fares are typically the most expensive at this time.

Reviews of airlines servicing Missouri

Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated November 10, 2025.
Read through reviews of airlines operating flights from Myrtle Beach to Missouri, such as Southwest, Delta, and American Airlines. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,235 reviews

Overall

8.0

Comfort

8.0

Boarding

8.1

Crew

8.6

Entertainment

7.5

Food

7.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Southwest
8.0
Very good
4,235 reviews
Southwest
8.0
Very good
4,235 reviews

Overall

8.0

Comfort

8.0

Boarding

8.1

Crew

8.6

Entertainment

7.5

Food

7.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Delta
7.9
Good
8,007 reviews
Southwest
8.0
Very good
4,235 reviews

Overall

8.0

Comfort

8.0

Boarding

8.1

Crew

8.6

Entertainment

7.5

Food

7.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
American Airlines
7.2
Good
11,045 reviews
Southwest
8.0
Very good
4,235 reviews

Overall

8.0

Comfort

8.0

Boarding

8.1

Crew

8.6

Entertainment

7.5

Food

7.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Spirit Airlines
6.3
Okay
8,136 reviews
Southwest
8.0
Very good
4,235 reviews

Overall

8.0

Comfort

8.0

Boarding

8.1

Crew

8.6

Entertainment

7.5

Food

7.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines

Related info for your journey

Find useful and relevant information for your journey from Myrtle Beach to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Myrtle Beach to Missouri?

    Most people fly from Myrtle Beach Intl (MYR) if they book a flight from Myrtle Beach to Missouri. Myrtle Beach Intl is conveniently located just 2.1 mi from Myrtle Beach’s city center.

  • How popular is this Myrtle Beach to Missouri flight route?

    This flight path from Myrtle Beach Intl to Missouri was viewed by 1 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

  • How long is the flight from Myrtle Beach to Missouri?

    Spirit Airlines, American Airlines, and Delta can get you from Myrtle Beach to Missouri in just under 4h 04m. Your travel time can differ by up to 4h 58m. Airlines will cover a distance of 727 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the most popular routes from Myrtle Beach to Missouri?

    The most popular flight routes from Myrtle Beach to Missouri are Myrtle Beach Intl - Springfield-Branson, Myrtle Beach Intl - Lambert-St Louis and Myrtle Beach Intl - Kansas City.

  • Can I find deals for flights from Myrtle Beach to Missouri that include hotel bookings?

    Yes. In addition to deals on Myrtle Beach to Missouri flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Myrtle Beach to Missouri?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Myrtle Beach to Missouri.

  • Can I find deals for business class flights from Myrtle Beach to Missouri?

    Yes. Cheapflights offers flight deals from Myrtle Beach to Missouri by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Myrtle Beach to Missouri?

    Currently, December is the cheapest month in which you can book a flight from Myrtle Beach to Missouri (average of $118). Flying from Myrtle Beach to Missouri in July is currently the most expensive (average of $248). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Myrtle Beach to Missouri

See prices for flight routes from nearby airports that may be better suited for you.
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Top 4 airlines flying from Myrtle Beach to Missouri

Discover the top 4 airlines that operate flights from Myrtle Beach to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 10, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$168Average$410FlexibilityNo cancel feeOn-timeN/A
Spirit AirlinesCheapest$199Average$250FlexibilityNo cancel feeOn-time65%
American AirlinesCheapest$204Average$387FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$281Average$399FlexibilityNo cancel feeOn-time63%

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