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$96+ Cheap flights from Myrtle Beach (MYR) to Missouri

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/17. Fares are subject to change and may not be available on all flights or dates of travel.
MYR — STL
Aug 23 — Aug 301
Sat 8/23
Sat 8/30
1 adult, Economy
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Cheap flight deals from Myrtle Beach to Missouri

Keep the following information in mind while searching for Myrtle Beach to Missouri flight deals. Data was last updated August 18, 2025.

Round-trip from

$221
(FlightHub)

One-way from

$96
(Cheapflightsfares)

Popular in

June

Cheapest in

February

Average price

$254

Good one-way deal

$178 or less
From Myrtle Beach Intl to Missouri
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One-way flight from Myrtle Beach Intl to Missouri
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Highest demand for flights based on searches. 12% potential increase in price ($50 potential increase over avg. RT price).
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Cheapest flight prices on average. 2% potential price decrease ($8 potential savings vs. average RT price).
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Average for round-trip flights in August 2025
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Price to beat on a one-way flight from Myrtle Beach Intl to Missouri.
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Find flight deals from Myrtle Beach to Missouri

Cheapest flights from Myrtle Beach to Missouri
Explore the most affordable flight options available from Myrtle Beach to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 18, 2025.

This FlightHub deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/187:00 amMYR - MCI
1 stop17h 46mSpirit Airlines
Mon 10/205:15 amMCI - MYR
1 stop11h 29mSpirit Airlines
Deal found 8/17$221
This Cheapflightsfares deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/185:20 pmMYR - MCI
1 stop6h 47mSpirit Airlines
Sun 9/215:15 amMCI - MYR
1 stop10h 10mSpirit Airlines
Deal found 8/18$239
This Kiwi.com deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/134:23 pmMYR - STL
1 stop18h 17mMultiple Airlines
Mon 9/154:00 pmSTL - MYR
2 stops26h 46mMultiple Airlines
Deal found 8/17$249
This Kiwi.com deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/255:20 pmMYR - STL
1 stop20h 42mMultiple Airlines
Mon 9/291:57 pmSTL - MYR
1 stop21h 32mMultiple Airlines
Deal found 8/17$253
This Kiwi.com deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/57:17 pmMYR - MCI
1 stop28h 50mSpirit Airlines
Tue 9/95:15 amMCI - MYR
1 stop6h 14mSpirit Airlines
Deal found 8/18$254
This FlightHub deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/134:23 pmMYR - STL
1 stop18h 17mMultiple Airlines
Sun 9/144:00 pmSTL - MYR
2 stops22h 19mMultiple Airlines
Deal found 8/17$269
This Kiwi.com deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/115:20 pmMYR - STL
1 stop20h 42mMultiple Airlines
Mon 9/151:57 pmSTL - MYR
1 stop21h 32mMultiple Airlines
Deal found 8/17$276
This Kiwi.com deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/115:20 pmMYR - STL
1 stop20h 42mMultiple Airlines
Sun 9/141:52 pmSTL - MYR
1 stop21h 05mMultiple Airlines
Deal found 8/17$285
This Kiwi.com deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/138:30 pmMYR - STL
1 stop17h 47mMultiple Airlines
Mon 11/177:45 pmSTL - MYR
2 stops22h 50mMultiple Airlines
Deal found 8/17$290
This Kiwi.com deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/174:09 pmMYR - MCI
2 stops26h 46mMultiple Airlines
Mon 10/205:15 amMCI - MYR
1 stop11h 29mMultiple Airlines
Deal found 8/18$291
This Delta deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/1610:36 amMYR - STL
1 stop6h 19mDelta
Tue 10/217:05 amSTL - MYR
1 stop5h 45mDelta
Deal found 8/17$295
This FlightHub deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/256:31 pmMYR - MCI
1 stop5h 22mSpirit Airlines
Mon 9/16:00 amMCI - MYR
1 stop12h 45mSpirit Airlines
Deal found 8/18$295

Cheapflights Fare Finder

 
Customize your flight search to find flights from Myrtle Beach to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 18, 2025.
Use the filters below to find and compare flights from Myrtle Beach to Missouri that are best for you.

Fly from

Myrtle Beach

Fly to

Missouri

Route

Depart

Return

Price

Myrtle BeachKansas City

MYR - MCI

MYRMCI

Myrtle Beach Intl

Sat 10/18

7:00 am-11:46 pm

1 stop17h 46m

Kansas City

Mon 10/20

5:15 am-5:44 pm

1 stop11h 29m

$221

Myrtle BeachKansas City

MYR - MCI

MYRMCI

Myrtle Beach Intl

Thu 9/18

5:20 pm-11:07 pm

1 stop6h 47m

Kansas City

Sun 9/21

5:15 am-4:25 pm

1 stop10h 10m

$239

Myrtle BeachSt. Louis

MYR - STL

MYRSTL

Myrtle Beach Intl

Sat 9/13

4:23 pm-9:40 am

1 stop18h 17m

Lambert-St Louis

Mon 9/15

4:00 pm-7:46 pm

2 stops26h 46m

$249

Myrtle BeachSt. Louis

MYR - STL

MYRSTL

Myrtle Beach Intl

Thu 9/25

5:20 pm-1:02 pm

1 stop20h 42m

Lambert-St Louis

Mon 9/29

1:57 pm-12:29 pm

1 stop21h 32m

$253

Myrtle BeachKansas City

MYR - MCI

MYRMCI

Myrtle Beach Intl

Fri 9/5

7:17 pm-11:07 pm

1 stop28h 50m

Kansas City

Tue 9/9

5:15 am-12:29 pm

1 stop6h 14m

$254

Myrtle BeachSt. Louis

MYR - STL

MYRSTL

Myrtle Beach Intl

Sat 9/13

4:23 pm-9:40 am

1 stop18h 17m

Lambert-St Louis

Sun 9/14

4:00 pm-3:19 pm

2 stops22h 19m

$269

Myrtle BeachSt. Louis

MYR - STL

MYRSTL

Myrtle Beach Intl

Thu 9/11

5:20 pm-1:02 pm

1 stop20h 42m

Lambert-St Louis

Mon 9/15

1:57 pm-12:29 pm

1 stop21h 32m

$276

Myrtle BeachSt. Louis

MYR - STL

MYRSTL

Myrtle Beach Intl

Thu 11/13

8:30 pm-1:17 pm

1 stop17h 47m

Lambert-St Louis

Mon 11/17

2:12 pm-7:35 pm

1 stop28h 23m

$276

Myrtle BeachSt. Louis

MYR - STL

MYRSTL

Myrtle Beach Intl

Thu 9/11

5:20 pm-1:02 pm

1 stop20h 42m

Lambert-St Louis

Sun 9/14

1:52 pm-11:57 am

1 stop21h 05m

$285

Myrtle BeachKansas City

MYR - MCI

MYRMCI

Myrtle Beach Intl

Fri 10/17

4:09 pm-5:55 pm

2 stops26h 46m

Kansas City

Mon 10/20

5:15 am-5:44 pm

1 stop11h 29m

$291

Flights are sorted by cheapest round-trip flights first.

Deals found on 8/16

Showing 1-10 of 36 results
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Best time to book a flight from Myrtle Beach to Missouri

Have a flexible travel schedule? Discover the best time to fly to Missouri from Myrtle Beach with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Myrtle Beach to Missouri

What is the cheapest month to book a flight from Myrtle Beach to Missouri?

Currently, August is the cheapest month in which you can book a flight from Myrtle Beach to Missouri (average of $311). Flying from Myrtle Beach to Missouri in March is currently the most expensive (average of $356). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MYR to MO?

Find hourly flight availability from Myrtle Beach to Missouri. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated August 18, 2025.

When flying from Myrtle Beach to Missouri, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Reviews of airlines servicing Missouri

Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated August 18, 2025.
Read through reviews of airlines operating flights from Myrtle Beach to Missouri, such as Southwest, Delta, and American Airlines. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,246 reviews

Food

7.0

Crew

8.6

Comfort

8.0

Boarding

8.1

Entertainment

7.5

Overall

8.0

Reviews

1 / 20
8.0
Excellent

Walter,Aug 2025

OAK - SAN

Dozens of flights and I've never seen a row's beverages forgotten. I even went back and asked the attendant to check on them and nothing. I really hope it didn't have something to do with the Black mother with her kid in the row. Otherwise it was a typical Southwest flight, rapid boarding, tolerable leg room.
Southwest
8.0
Very good
4,246 reviews
Southwest
8.0
Very good
4,246 reviews

Food

7.0

Crew

8.6

Comfort

8.0

Boarding

8.1

Entertainment

7.5

Overall

8.0

Reviews

1 / 20
8.0
Excellent

Walter,Aug 2025

OAK - SAN

Dozens of flights and I've never seen a row's beverages forgotten. I even went back and asked the attendant to check on them and nothing. I really hope it didn't have something to do with the Black mother with her kid in the row. Otherwise it was a typical Southwest flight, rapid boarding, tolerable leg room.
Delta
8.0
Very good
7,981 reviews
Southwest
8.0
Very good
4,246 reviews

Food

7.0

Crew

8.6

Comfort

8.0

Boarding

8.1

Entertainment

7.5

Overall

8.0

Reviews

1 / 20
8.0
Excellent

Walter,Aug 2025

OAK - SAN

Dozens of flights and I've never seen a row's beverages forgotten. I even went back and asked the attendant to check on them and nothing. I really hope it didn't have something to do with the Black mother with her kid in the row. Otherwise it was a typical Southwest flight, rapid boarding, tolerable leg room.
American Airlines
7.2
Good
10,000 reviews
Southwest
8.0
Very good
4,246 reviews

Food

7.0

Crew

8.6

Comfort

8.0

Boarding

8.1

Entertainment

7.5

Overall

8.0

Reviews

1 / 20
8.0
Excellent

Walter,Aug 2025

OAK - SAN

Dozens of flights and I've never seen a row's beverages forgotten. I even went back and asked the attendant to check on them and nothing. I really hope it didn't have something to do with the Black mother with her kid in the row. Otherwise it was a typical Southwest flight, rapid boarding, tolerable leg room.
Spirit Airlines
6.3
Okay
8,038 reviews
Southwest
8.0
Very good
4,246 reviews

Food

7.0

Crew

8.6

Comfort

8.0

Boarding

8.1

Entertainment

7.5

Overall

8.0

Reviews

1 / 20
8.0
Excellent

Walter,Aug 2025

OAK - SAN

Dozens of flights and I've never seen a row's beverages forgotten. I even went back and asked the attendant to check on them and nothing. I really hope it didn't have something to do with the Black mother with her kid in the row. Otherwise it was a typical Southwest flight, rapid boarding, tolerable leg room.

Related info for your journey

Find useful and relevant information for your journey from Myrtle Beach to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Myrtle Beach to Missouri?

    Most people fly from Myrtle Beach Intl (MYR) if they book a flight from Myrtle Beach to Missouri. Myrtle Beach Intl is conveniently located just 2.1 mi from Myrtle Beach’s city center.

  • How popular is this Myrtle Beach to Missouri flight route?

    This flight path from Myrtle Beach Intl to Missouri was viewed by 1 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

  • How long is the flight from Myrtle Beach to Missouri?

    Spirit Airlines, American Airlines, and Allegiant Air can get you from Myrtle Beach to Missouri in just under 4h 29m. Your travel time can differ by up to 13h 17m. Airlines will cover a distance of 849 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines to fly from Myrtle Beach to Missouri one-way?

    The cheapest airline one-way is Spirit Airlines, with whom users have recently found tickets for as low as $96. However, be on the lookout for offers from Allegiant Air and American Airlines, as they are both options that can get you from Myrtle Beach to Missouri for a low price.

  • What are the most popular routes from Myrtle Beach to Missouri?

    The most popular flight routes from Myrtle Beach to Missouri are Myrtle Beach Intl - Lambert-St Louis, Myrtle Beach Intl - Kansas City and Myrtle Beach Intl - Springfield-Branson.

  • What are the cheapest flights from Myrtle Beach to Missouri?

    On average you can expect to pay $178 for a flight from Myrtle Beach to Missouri. The cheapest flight overall is $165 while the most popular route, (Myrtle Beach Intl - Lambert-St Louis) is currently priced at $253.

  • Can I find deals for flights from Myrtle Beach to Missouri that include hotel bookings?

    Yes. In addition to deals on Myrtle Beach to Missouri flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Myrtle Beach to Missouri?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Myrtle Beach to Missouri.

  • Can I find deals for business class flights from Myrtle Beach to Missouri?

    Yes. Cheapflights offers flight deals from Myrtle Beach to Missouri by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Myrtle Beach to Missouri?

    Currently, August is the cheapest month in which you can book a flight from Myrtle Beach to Missouri (average of $311). Flying from Myrtle Beach to Missouri in March is currently the most expensive (average of $356). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

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Alternative routes for Myrtle Beach to Missouri

See prices for flight routes from nearby airports that may be better suited for you.
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Top 4 airlines flying from Myrtle Beach to Missouri

Discover the top 4 airlines that operate flights from Myrtle Beach to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 18, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$196Average$378FlexibilityNo cancel feeOn-timeN/A
Spirit AirlinesCheapest$199Average$225FlexibilityNo cancel feeOn-time65%
American AirlinesCheapest$204Average$415FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$281Average$394FlexibilityNo cancel feeOn-time63%

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