$124+ Cheap flights from Myrtle Beach (MYR) to Missouri
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/21. Fares are subject to change and may not be available on all flights or dates of travel.
MYR — STL
Apr 27 — May 41
Round-trip
1 adult, Economy
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Find cheap flights from Myrtle Beach to Missouri with Cheapflights
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Cheapest flights from Myrtle Beach to MissouriExplore the most affordable flight options available from Myrtle Beach to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 28, 2026.
Explore the most affordable flight options available from Myrtle Beach to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 28, 2026.
This Delta deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/711:00 am
MYR
- STL
1 stop5h 40m
Delta
Tue 5/126:57 pm
STL
- MYR
1 stop4h 01m
Delta
Deal found 3/24![Delta logo]()
$272
This American Airlines deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/510:28 am
MYR
- MCI
1 stop5h 29m
American Airlines
Tue 5/121:40 pm
MCI
- MYR
1 stop7h 16m
American Airlines
Deal found 3/25![American Airlines logo]()
$281
This Southwest deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/57:35 am
MYR
- MCI
1 stop5h 15m
Southwest
Tue 5/1212:20 pm
MCI
- MYR
2 stops7h 10m
Southwest
Deal found 3/25![Southwest logo]()
$286
This Kiwi.com deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/912:05 pm
MYR
- STL
1 stop12h 20m
Multiple Airlines
Mon 4/134:59 pm
STL
- MYR
1 stop17h 06m
Multiple Airlines
Deal found 3/26![Multiple Airlines logo]()
$287
This Delta deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/811:00 am
MYR
- STL
1 stop5h 40m
Delta
Tue 5/126:21 am
STL
- MYR
1 stop7h 09m
Delta
Deal found 3/24![Delta logo]()
$296
This Delta deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/711:00 am
MYR
- STL
1 stop5h 40m
Delta
Mon 5/117:01 pm
STL
- MYR
1 stop3h 57m
Delta
Deal found 3/24![Delta logo]()
$297
This American Airlines deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/66:04 am
MYR
- MCI
2 stops7h 56m
American Airlines
Tue 5/121:40 pm
MCI
- MYR
2 stops8h 22m
American Airlines
Deal found 3/25![American Airlines logo]()
$307
This United Airlines deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/73:14 pm
MYR
- MCI
1 stop7h 50m
United Airlines
Tue 5/126:17 am
MCI
- MYR
1 stop7h 01m
United Airlines
Deal found 3/24![United Airlines logo]()
$310
This Southwest deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/101:45 pm
MYR
- STL
1 stop7h 00m
Southwest
Tue 4/1411:35 am
STL
- MYR
1 stop5h 00m
Southwest
Deal found 3/26![Southwest logo]()
$313
This American Airlines deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/711:11 am
MYR
- MCI
2 stops7h 15m
American Airlines
Tue 5/123:11 pm
MCI
- MYR
1 stop6h 51m
American Airlines
Deal found 3/24![American Airlines logo]()
$315
This United Airlines deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/83:14 pm
MYR
- STL
1 stop6h 59m
United Airlines
Mon 5/117:45 am
STL
- MYR
1 stop5h 33m
United Airlines
Deal found 3/24![United Airlines logo]()
$316
This Delta deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/1712:05 pm
MYR
- STL
1 stop8h 21m
Delta
Mon 4/206:50 pm
STL
- MYR
1 stop4h 24m
Delta
Deal found 3/26![Delta logo]()
$321
Best flights from Myrtle Beach to MissouriDiscover carefully curated flight deals from Myrtle Beach to Missouri that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 28, 2026.
Discover carefully curated flight deals from Myrtle Beach to Missouri that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 28, 2026.
This Delta deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/711:00 am
MYR
- STL
1 stop5h 40m
Delta
Tue 5/126:57 pm
STL
- MYR
1 stop4h 01m
Delta
Deal found 3/24![Delta logo]()
$272
This Kiwi.com deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/912:05 pm
MYR
- STL
1 stop12h 20m
Multiple Airlines
Mon 4/134:59 pm
STL
- MYR
1 stop17h 06m
Multiple Airlines
Deal found 3/26![Multiple Airlines logo]()
$287
This Southwest deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/101:45 pm
MYR
- STL
1 stop7h 00m
Southwest
Tue 4/1411:35 am
STL
- MYR
1 stop5h 00m
Southwest
Deal found 3/26![Southwest logo]()
$313
This United Airlines deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/83:14 pm
MYR
- STL
1 stop6h 59m
United Airlines
Mon 5/117:45 am
STL
- MYR
1 stop5h 33m
United Airlines
Deal found 3/24![United Airlines logo]()
$316
This American Airlines deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/165:00 am
MYR
- SGF
1 stop7h 04m
American Airlines
Mon 5/186:24 pm
SGF
- MYR
1 stop4h 33m
American Airlines
Deal found 3/24![American Airlines logo]()
$406
This Delta deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/176:00 am
MYR
- STL
1 stop6h 56m
Delta
Mon 4/206:48 am
STL
- MYR
1 stop4h 07m
Delta
Deal found 3/25![Delta logo]()
$321
This Southwest deal was found by Cheapflights users on 3/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/87:55 am
MYR
- STL
1 stop4h 20m
Southwest
Wed 7/151:10 pm
STL
- MYR
1 stop7h 00m
Southwest
Deal found 3/28![Southwest logo]()
$351
This Delta deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/56:45 pm
MYR
- SGF
1 stop4h 44m
Delta
Sat 9/123:30 pm
SGF
- MYR
1 stop7h 09m
Delta
Deal found 3/24![Delta logo]()
$323
This United Airlines deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/110:28 am
MYR
- SGF
2 stops11h 16m
United Airlines
Sat 9/55:40 am
SGF
- MYR
1 stop9h 17m
United Airlines
Deal found 3/27![United Airlines logo]()
$370
This Delta deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/96:00 am
MYR
- STL
1 stop4h 49m
Delta
Mon 5/117:01 pm
STL
- MYR
1 stop3h 57m
Delta
Deal found 3/24![Delta logo]()
$338
This United Airlines deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/13:14 pm
MYR
- MCI
1 stop7h 50m
United Airlines
Fri 5/88:00 am
MCI
- MYR
1 stop5h 18m
United Airlines
Deal found 3/24![United Airlines logo]()
$397
This Delta deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/811:00 am
MYR
- STL
1 stop5h 40m
Delta
Sun 5/105:15 pm
STL
- MYR
1 stop5h 43m
Delta
Deal found 3/24![Delta logo]()
$348
This Southwest deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/1410:55 am
MYR
- MCI
2 stops7h 45m
Southwest
Sun 5/177:55 am
MCI
- MYR
1 stop10h 35m
Southwest
Deal found 3/27![Southwest logo]()
$426
This American Airlines deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/1511:11 am
MYR
- SGF
2 stops7h 24m
American Airlines
Sun 5/173:36 pm
SGF
- MYR
1 stop7h 21m
American Airlines
Deal found 3/27![American Airlines logo]()
$482
This Delta deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/96:54 pm
MYR
- STL
1 stop6h 04m
Delta
Sat 4/116:32 am
STL
- MYR
1 stop4h 38m
Delta
Deal found 3/25![Delta logo]()
$351
This Southwest deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/103:45 pm
MYR
- MCI
2 stops8h 10m
Southwest
Tue 4/145:25 am
MCI
- MYR
2 stops7h 05m
Southwest
Deal found 3/26![Southwest logo]()
$426
This United Airlines deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/163:14 pm
MYR
- SGF
1 stop7h 48m
United Airlines
Sun 5/176:00 am
SGF
- MYR
1 stop7h 18m
United Airlines
Deal found 3/24![United Airlines logo]()
$459
This Delta deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/247:54 pm
MYR
- STL
1 stop5h 02m
Delta
Tue 6/303:45 pm
STL
- MYR
1 stop5h 05m
Delta
Deal found 3/24![Delta logo]()
$351
This Southwest deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/162:10 pm
MYR
- MCI
1 stop7h 25m
Southwest
Tue 6/302:30 pm
MCI
- MYR
1 stop6h 15m
Southwest
Deal found 3/25![Southwest logo]()
$437
This Delta deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/286:00 am
MYR
- MCI
1 stop4h 29m
Delta
Mon 6/15:13 pm
MCI
- MYR
1 stop5h 45m
Delta
Deal found 3/26![Delta logo]()
$359
This Southwest deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/13:45 pm
MYR
- MCI
2 stops8h 10m
Southwest
Fri 5/812:05 pm
MCI
- MYR
2 stops5h 40m
Southwest
Deal found 3/24![Southwest logo]()
$447
This United Airlines deal was found by Cheapflights users on 3/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/303:14 pm
MYR
- MCI
1 stop7h 50m
United Airlines
Mon 5/46:17 am
MCI
- MYR
1 stop7h 01m
United Airlines
Deal found 3/28![United Airlines logo]()
$513
This Southwest deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/2410:55 am
MYR
- MCI
2 stops9h 00m
Southwest
Fri 5/15:30 am
MCI
- MYR
2 stops6h 35m
Southwest
Deal found 3/26![Southwest logo]()
$472
This United Airlines deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/2710:34 am
MYR
- MCI
2 stops12h 08m
United Airlines
Sun 5/317:10 pm
MCI
- MYR
2 stops13h 49m
United Airlines
Deal found 3/24![United Airlines logo]()
$520
This United Airlines deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/153:14 pm
MYR
- JLN
2 stops9h 30m
United Airlines
Mon 5/182:28 pm
JLN
- MYR
2 stops22h 50m
United Airlines
Deal found 3/24![United Airlines logo]()
$623
This United Airlines deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/143:14 pm
MYR
- JLN
1 stop23h 23m
United Airlines
Mon 5/189:06 am
JLN
- MYR
1 stop28h 12m
United Airlines
Deal found 3/24![United Airlines logo]()
$681
This United Airlines deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/1411:30 am
MYR
- JLN
1 stop27h 07m
United Airlines
Sun 5/179:06 am
JLN
- MYR
1 stop28h 12m
United Airlines
Deal found 3/24![United Airlines logo]()
$690
This United Airlines deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/153:14 pm
MYR
- JLN
2 stops9h 30m
United Airlines
Sun 5/179:06 am
JLN
- MYR
1 stop28h 12m
United Airlines
Deal found 3/24![United Airlines logo]()
$701
This United Airlines deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/163:14 pm
MYR
- JLN
2 stops33h 30m
United Airlines
Mon 5/189:06 am
JLN
- MYR
1 stop28h 12m
United Airlines
Deal found 3/24![United Airlines logo]()
$745
Last-minute flights from Myrtle Beach to MissouriDiscover last-minute flight deals from Myrtle Beach to Missouri. Data last updated March 28, 2026 and is based on user searches.
Discover last-minute flight deals from Myrtle Beach to Missouri. Data last updated March 28, 2026 and is based on user searches.
This United Airlines deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/13:15 pm
MYR
- STL
1 stop6h 58m
United Airlines
Sun 4/56:30 am
STL
- MYR
1 stop6h 47m
United Airlines
Deal found 3/24![United Airlines logo]()
$346
This Delta deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/16:00 am
MYR
- STL
1 stop6h 09m
Delta
Sun 4/57:03 am
STL
- MYR
1 stop5h 28m
Delta
Deal found 3/27![Delta logo]()
$351
This American Airlines deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/16:00 am
MYR
- STL
2 stops7h 44m
American Airlines
Sun 4/59:35 am
STL
- MYR
1 stop5h 58m
American Airlines
Deal found 3/27![American Airlines logo]()
$356
This Kiwi.com deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/912:05 pm
MYR
- STL
1 stop12h 20m
Multiple Airlines
Mon 4/134:59 pm
STL
- MYR
1 stop17h 06m
Multiple Airlines
Deal found 3/26![Multiple Airlines logo]()
$287
This Southwest deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/101:45 pm
MYR
- STL
1 stop7h 00m
Southwest
Tue 4/1411:35 am
STL
- MYR
1 stop5h 00m
Southwest
Deal found 3/26![Southwest logo]()
$313
This American Airlines deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/105:00 am
MYR
- SGF
1 stop6h 49m
American Airlines
Sun 4/126:24 pm
SGF
- MYR
1 stop4h 33m
American Airlines
Deal found 3/26![American Airlines logo]()
$339
This Kiwi.com deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/106:28 pm
MYR
- MCI
1 stop18h 01m
Multiple Airlines
Tue 4/1412:24 pm
MCI
- MYR
1 stop26h 19m
Multiple Airlines
Deal found 3/26![Multiple Airlines logo]()
$348
This Kiwi.com deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/106:28 pm
MYR
- MCI
1 stop18h 01m
Spirit Airlines
Tue 4/146:04 pm
MCI
- MYR
2 stops37h 09m
Spirit Airlines
Deal found 3/26![Spirit Airlines logo]()
$368
This Kiwi.com deal was found by Cheapflights users on 3/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/126:28 pm
MYR
- MCI
1 stop18h 01m
Multiple Airlines
Thu 4/1611:53 am
MCI
- MYR
2 stops10h 36m
Multiple Airlines
Deal found 3/28![Multiple Airlines logo]()
$351
This Delta deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/1712:05 pm
MYR
- STL
1 stop8h 21m
Delta
Mon 4/206:50 pm
STL
- MYR
1 stop4h 24m
Delta
Deal found 3/26![Delta logo]()
$321
This American Airlines deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/1712:36 pm
MYR
- STL
1 stop7h 57m
American Airlines
Mon 4/2012:27 pm
STL
- MYR
2 stops8h 57m
American Airlines
Deal found 3/25![American Airlines logo]()
$326
This United Airlines deal was found by Cheapflights users on 3/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/253:15 pm
MYR
- STL
1 stop6h 58m
United Airlines
Sat 5/27:45 am
STL
- MYR
2 stops8h 28m
United Airlines
Deal found 3/28![United Airlines logo]()
$352
One-way flights from Myrtle Beach to MissouriSearch for one-way flight options from Myrtle Beach to Missouri. Find affordable one-way fares based on user searches. Data last updated March 28, 2026.
Search for one-way flight options from Myrtle Beach to Missouri. Find affordable one-way fares based on user searches. Data last updated March 28, 2026.
This Delta deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/223:57 pm
MYR
- STL
1 stop8h 16m
Delta
Deal found 3/26![Delta logo]()
$124
This Kiwi.com deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/225:55 pm
MYR
- MCI
2 stops18h 03m
Multiple Airlines
Deal found 3/25![Multiple Airlines logo]()
$125
This Kiwi.com deal was found by Cheapflights users on 3/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/2911:52 am
MYR
- STL
2 stops23h 34m
Multiple Airlines
Deal found 3/28![Multiple Airlines logo]()
$132
This Kiwi.com deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/215:55 pm
MYR
- STL
2 stops13h 55m
Multiple Airlines
Deal found 3/25![Multiple Airlines logo]()
$134
This Kiwi.com deal was found by Cheapflights users on 3/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/282:23 pm
MYR
- STL
2 stops17h 27m
Multiple Airlines
Deal found 3/28![Multiple Airlines logo]()
$137
This Kiwi.com deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/2711:52 am
MYR
- STL
2 stops43h 58m
Multiple Airlines
Deal found 3/25![Multiple Airlines logo]()
$138
This Kiwi.com deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/269:39 pm
MYR
- MCI
2 stops20h 50m
Multiple Airlines
Deal found 3/27![Multiple Airlines logo]()
$138
This Kiwi.com deal was found by Cheapflights users on 3/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/258:43 pm
MYR
- STL
2 stops35h 07m
Multiple Airlines
Deal found 3/28![Multiple Airlines logo]()
$139
This Kiwi.com deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/254:01 pm
MYR
- STL
2 stops39h 49m
Frontier
Deal found 3/27![Frontier logo]()
$140
This Kiwi.com deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/2311:52 am
MYR
- MCI
2 stops23h 42m
Multiple Airlines
Deal found 3/25![Multiple Airlines logo]()
$140
This Southwest deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/257:10 am
MYR
- STL
2 stops7h 25m
Southwest
Deal found 3/26![Southwest logo]()
$143
This United Airlines deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/253:15 pm
MYR
- STL
1 stop6h 58m
United Airlines
Deal found 3/26![United Airlines logo]()
$144
Find flight deals from Myrtle Beach to Missouri
Keep the following information in mind while searching for Myrtle Beach to Missouri flight deals. Data was last updated March 28, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $272 (Delta) |
One-way from | $124 (Delta) |
Popular in | March |
Cheapest in | August |
Average price | $494 |
Cheapflights Fare Finder
Customize your flight search to find flights from Myrtle Beach to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 28, 2026.
Use the filters below to find and compare flights from Myrtle Beach to Missouri that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Myrtle BeachSt. Louis
MYR - STL
MYRSTL
Myrtle Beach Intl
Thu 5/7
11:00 am-3:40 pm
1 stop5h 40m
Lambert-St Louis
Tue 5/12
6:57 pm-11:58 pm
1 stop4h 01m
$272
Myrtle BeachSt. Louis
MYR - STL
MYRSTL
Myrtle Beach Intl
Thu 4/9
12:05 pm-11:25 pm
1 stop12h 20m
Lambert-St Louis
Mon 4/13
4:59 pm-11:05 am
1 stop17h 06m
$287
Myrtle BeachSt. Louis
MYR - STL
MYRSTL
Myrtle Beach Intl
Fri 4/10
1:45 pm-7:45 pm
1 stop7h 00m
Lambert-St Louis
Tue 4/14
11:35 am-5:35 pm
1 stop5h 00m
$313
Myrtle BeachSt. Louis
MYR - STL
MYRSTL
Myrtle Beach Intl
Fri 5/8
3:14 pm-9:13 pm
1 stop6h 59m
Lambert-St Louis
Mon 5/11
7:45 am-2:18 pm
1 stop5h 33m
$316
Myrtle BeachSt. Louis
MYR - STL
MYRSTL
Myrtle Beach Intl
Fri 4/17
6:00 am-11:56 am
1 stop6h 56m
Lambert-St Louis
Mon 4/20
6:48 am-11:55 am
1 stop4h 07m
$321
Myrtle BeachSpringfield
MYR - SGF
MYRSGF
Myrtle Beach Intl
Sat 9/5
6:45 pm-10:29 pm
1 stop4h 44m
Springfield-Branson
Sat 9/12
3:30 pm-11:39 pm
1 stop7h 09m
$323
Quickest round-trip
Myrtle BeachSt. Louis
MYR - STL
MYRSTL
Myrtle Beach Intl
Sat 5/9
6:00 am-9:49 am
1 stop4h 49m
Lambert-St Louis
Mon 5/11
7:01 pm-11:58 pm
1 stop3h 57m
$338
Myrtle BeachSt. Louis
MYR - STL
MYRSTL
Myrtle Beach Intl
Fri 5/8
11:00 am-3:40 pm
1 stop5h 40m
Lambert-St Louis
Sun 5/10
5:15 pm-11:58 pm
1 stop5h 43m
$348
Myrtle BeachSt. Louis
MYR - STL
MYRSTL
Myrtle Beach Intl
Wed 7/8
7:55 am-11:15 am
1 stop4h 20m
Lambert-St Louis
Wed 7/15
1:10 pm-9:10 pm
1 stop7h 00m
$351
Myrtle BeachSt. Louis
MYR - STL
MYRSTL
Myrtle Beach Intl
Thu 4/9
6:54 pm-11:58 pm
1 stop6h 04m
Lambert-St Louis
Sat 4/11
6:32 am-12:10 pm
1 stop4h 38m
$351
Showing 1-10 of 53 resultsSorted by cheapest first
Best time to book a flight from Myrtle Beach to Missouri
Have a flexible travel schedule? Discover the best time to fly to Missouri from Myrtle Beach with our price prediction graph.
MYR-STL
MYR-MCI
MYR-SGF
MYR-JLN
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Myrtle Beach to Missouri
MYR-USMO
MYR-STL
MYR-MCI
MYR-SGF
MYR-JLN
What is the cheapest month to book a flight from Myrtle Beach to Missouri?
Currently, December is the cheapest month in which you can book a flight from Myrtle Beach to Missouri (average of $118). Flying from Myrtle Beach to Missouri in March is currently the most expensive (average of $295). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from MYR to MO?
Find hourly flight availability from Myrtle Beach to Missouri. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated March 28, 2026.
When flying from Myrtle Beach to Missouri, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.
How much does it cost to fly round-trip from Myrtle Beach to Missouri?
Reviews of airlines servicing Missouri
Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated March 28, 2026.
Read through reviews of airlines operating flights from Myrtle Beach to Missouri, such as Southwest,Delta, andAmerican Airlines. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Overall
8.0
Food
7.0
Boarding
8.1
Entertainment
7.5
Comfort
8.0
Crew
8.6
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Overall
8.0
Food
7.0
Boarding
8.1
Entertainment
7.5
Comfort
8.0
Crew
8.6
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Overall
8.0
Food
7.0
Boarding
8.1
Entertainment
7.5
Comfort
8.0
Crew
8.6
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Overall
8.0
Food
7.0
Boarding
8.1
Entertainment
7.5
Comfort
8.0
Crew
8.6
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Related info for your journey
Find useful and relevant information for your journey from Myrtle Beach to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Myrtle Beach to Missouri
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Complete your trip
Complete your trip to Missouri by adding a car rental and/or hotel reservation to your travel itinerary.
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Myrtle Beach and Missouri flights
Browse other Myrtle Beach and Missouri flight options. Last updated on March 28, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Myrtle Beach to Missouri flights
Consider these flights traveling from Myrtle Beach to Missouri.
Top 3 airlines flying from Myrtle Beach to Missouri
Discover the top 3 airlines that operate flights from Myrtle Beach to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 28, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$128 | Average$364 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$177 | Average$372 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$231 | Average$421 | FlexibilityNo cancel fee | On-time63% |