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$89+ Cheap flights from Myrtle Beach (MYR) to Missouri

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/24. Fares are subject to change and may not be available on all flights or dates of travel.
MYR — STL
Feb 28 — Mar 71
Sat 2/28
Sat 3/7
1 adult, Economy
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Cheap flight deals from Myrtle Beach to Missouri

Cheapest flights from Myrtle Beach to Missouri
Explore the most affordable flight options available from Myrtle Beach to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 29, 2026.

This Kiwi.com deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/1210:30 am
MYR
-
STL
1 stop14h 29m
Multiple Airlines
Mon 2/168:22 pm
STL
-
MYR
2 stops34h 51m
Multiple Airlines
Deal found 1/28$229
This Kiwi.com deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/312:39 pm
MYR
-
STL
1 stop10h 48m
Multiple Airlines
Tue 3/104:51 pm
STL
-
MYR
2 stops21h 04m
Multiple Airlines
Deal found 1/27$231
This Kiwi.com deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/273:20 pm
MYR
-
STL
1 stop10h 07m
Multiple Airlines
Fri 3/61:09 pm
STL
-
MYR
2 stops18h 04m
Multiple Airlines
Deal found 1/28$255
This Kiwi.com deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/1712:05 pm
MYR
-
STL
1 stop12h 14m
Multiple Airlines
Fri 3/2012:16 pm
STL
-
MYR
2 stops25h 16m
Multiple Airlines
Deal found 1/27$256
This Kiwi.com deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/410:00 am
MYR
-
STL
2 stops14h 33m
Multiple Airlines
Sat 2/75:42 pm
STL
-
MYR
1 stop17h 30m
Multiple Airlines
Deal found 1/27$263
This American Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/76:00 am
MYR
-
SGF
1 stop6h 18m
American Airlines
Mon 3/96:15 pm
SGF
-
MYR
1 stop4h 40m
American Airlines
Deal found 1/27$269
This Kiwi.com deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/1210:30 am
MYR
-
MCI
2 stops24h 33m
Multiple Airlines
Mon 2/1611:26 am
MCI
-
MYR
1 stop19h 47m
Multiple Airlines
Deal found 1/28$276
This Kiwi.com deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/129:09 am
MYR
-
MCI
1 stop26h 21m
Spirit Airlines
Mon 2/1611:26 am
MCI
-
MYR
1 stop19h 47m
Spirit Airlines
Deal found 1/28$293
This Kiwi.com deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/66:18 pm
MYR
-
MCI
2 stops40h 35m
Multiple Airlines
Thu 3/511:26 am
MCI
-
MYR
1 stop19h 47m
Multiple Airlines
Deal found 1/27$328
This American Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/195:10 am
MYR
-
SGF
1 stop7h 08m
American Airlines
Wed 2/255:31 pm
SGF
-
MYR
1 stop4h 25m
American Airlines
Deal found 1/27$329
This Kiwi.com deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/510:00 am
MYR
-
MCI
2 stops26h 50m
Multiple Airlines
Thu 3/511:26 am
MCI
-
MYR
1 stop19h 47m
Multiple Airlines
Deal found 1/27$332
This Kiwi.com deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/1610:27 am
MYR
-
STL
1 stop13h 52m
Multiple Airlines
Sun 4/1911:21 am
STL
-
MYR
2 stops21h 21m
Multiple Airlines
Deal found 1/28$340

Find flight deals from Myrtle Beach to Missouri

Keep the following information in mind while searching for Myrtle Beach to Missouri flight deals. Data was last updated January 29, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$229
(Kiwi.com)

One-way from

$89
(Kiwi.com)

Popular in

January

Cheapest in

August

Average price

$504
Provider with most accurate pricing for Myrtle Beach Intl-Lambert-St Louis flight deals.
Search Deals
Provider most trusted by Cheapflights users for Myrtle Beach Intl-Lambert-St Louis flights.
Search Deals
From Myrtle Beach Intl to Missouri
Search Deals
One-way flight from Myrtle Beach Intl to Missouri
Search Deals
Highest demand for flights based on searches. 14% potential increase in price ($65 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 3% potential price decrease ($12 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in January 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Myrtle Beach to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 29, 2026.
Use the filters below to find and compare flights from Myrtle Beach to Missouri that are best for you.

Fly from

Myrtle Beach

Fly to

Missouri

Route

Depart

Return

Price

Myrtle BeachSt. Louis

MYR - STL

MYRSTL

Myrtle Beach Intl

Thu 2/12

10:30 am-11:59 pm

1 stop14h 29m

Lambert-St Louis

Mon 2/16

8:22 pm-8:13 am

2 stops34h 51m

$229

Myrtle BeachSt. Louis

MYR - STL

MYRSTL

Myrtle Beach Intl

Tue 3/17

12:05 pm-11:19 pm

1 stop12h 14m

Lambert-St Louis

Fri 3/20

12:16 pm-2:32 pm

2 stops25h 16m

$256

Myrtle BeachKansas City

MYR - MCI

MYRMCI

Myrtle Beach Intl

Thu 2/12

10:30 am-10:03 am

2 stops24h 33m

Kansas City

Mon 2/16

11:26 am-8:13 am

1 stop19h 47m

$276

Myrtle BeachKansas City

MYR - MCI

MYRMCI

Myrtle Beach Intl

Sun 2/22

9:09 am-10:30 am

1 stop26h 21m

Kansas City

Wed 2/25

4:24 pm-11:44 am

1 stop18h 20m

$277

Myrtle BeachKansas City

MYR - MCI

MYRMCI

Myrtle Beach Intl

Thu 2/12

9:09 am-10:30 am

1 stop26h 21m

Kansas City

Mon 2/16

11:26 am-8:13 am

1 stop19h 47m

$293

Myrtle BeachSt. Louis

MYR - STL

MYRSTL

Myrtle Beach Intl

Fri 2/27

3:20 pm-12:27 am

1 stop10h 07m

Lambert-St Louis

Fri 3/6

7:47 am-10:59 am

1 stop26h 12m

$309

Myrtle BeachSpringfield

MYR - SGF

MYRSGF

Myrtle Beach Intl

Thu 2/19

5:10 am-11:18 am

1 stop7h 08m

Springfield-Branson

Wed 2/25

5:31 pm-10:56 pm

1 stop4h 25m

$329

Myrtle BeachSpringfield

MYR - SGF

MYRSGF

Myrtle Beach Intl

Tue 3/24

6:54 am-12:28 pm

1 stop6h 34m

Springfield-Branson

Tue 3/31

1:15 pm-8:45 pm

1 stop6h 30m

$329

Myrtle BeachSt. Louis

MYR - STL

MYRSTL

Myrtle Beach Intl

Tue 3/3

3:00 pm-9:00 pm

1 stop7h 00m

Lambert-St Louis

Tue 3/10

7:30 am-3:05 pm

1 stop6h 35m

$343

Myrtle BeachSt. Louis

MYR - STL

MYRSTL

Myrtle Beach Intl

Fri 5/8

7:50 pm-11:38 pm

1 stop4h 48m

Lambert-St Louis

Mon 5/11

5:30 pm-11:38 pm

1 stop5h 08m

$351

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/27

Showing 1-10 of 38 results
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Best time to book a flight from Myrtle Beach to Missouri

Have a flexible travel schedule? Discover the best time to fly to Missouri from Myrtle Beach with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Myrtle Beach to Missouri

What is the cheapest month to book a flight from Myrtle Beach to Missouri?

Currently, December is the cheapest month in which you can book a flight from Myrtle Beach to Missouri (average of $118). Flying from Myrtle Beach to Missouri in July is currently the most expensive (average of $248). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Missouri

Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated January 29, 2026.
Read through reviews of airlines operating flights from Myrtle Beach to Missouri, such as Southwest, Delta, and American Airlines. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,267 reviews

Comfort

8.0

Crew

8.6

Boarding

8.1

Food

7.0

Entertainment

7.5

Overall

8.0

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
Southwest
8.0
Very good
4,267 reviews
Southwest
8.0
Very good
4,267 reviews

Comfort

8.0

Crew

8.6

Boarding

8.1

Food

7.0

Entertainment

7.5

Overall

8.0

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
Delta
7.9
Good
8,128 reviews
Southwest
8.0
Very good
4,267 reviews

Comfort

8.0

Crew

8.6

Boarding

8.1

Food

7.0

Entertainment

7.5

Overall

8.0

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
American Airlines
7.2
Good
11,205 reviews
Southwest
8.0
Very good
4,267 reviews

Comfort

8.0

Crew

8.6

Boarding

8.1

Food

7.0

Entertainment

7.5

Overall

8.0

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

Related info for your journey

Find useful and relevant information for your journey from Myrtle Beach to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Myrtle Beach to Missouri?

    Most people fly from Myrtle Beach Intl (MYR) if they book a flight from Myrtle Beach to Missouri. Myrtle Beach Intl is conveniently located just 2.1 mi from Myrtle Beach’s city center.

  • How popular is this Myrtle Beach to Missouri flight route?

    This flight path from Myrtle Beach Intl to Missouri was viewed by 1 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

  • How long is the flight from Myrtle Beach to Missouri?

    Spirit Airlines, American Airlines, and Southwest can get you from Myrtle Beach to Missouri in just under 7h. Your travel time can differ by up to 19h 21m. Airlines will cover a distance of 727 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the most popular routes from Myrtle Beach to Missouri?

    The most popular flight routes from Myrtle Beach to Missouri are Myrtle Beach Intl - Springfield-Branson, Myrtle Beach Intl - Kansas City and Myrtle Beach Intl - Lambert-St Louis.

  • Can I find deals for flights from Myrtle Beach to Missouri that include hotel bookings?

    Yes. In addition to deals on Myrtle Beach to Missouri flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Myrtle Beach to Missouri?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Myrtle Beach to Missouri.

  • Can I find deals for business class flights from Myrtle Beach to Missouri?

    Yes. Cheapflights offers flight deals from Myrtle Beach to Missouri by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Myrtle Beach to Missouri?

    Currently, December is the cheapest month in which you can book a flight from Myrtle Beach to Missouri (average of $118). Flying from Myrtle Beach to Missouri in July is currently the most expensive (average of $248). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Myrtle Beach to Missouri

See prices for flight routes from nearby airports that may be better suited for you.
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Top 3 airlines flying from Myrtle Beach to Missouri

Discover the top 3 airlines that operate flights from Myrtle Beach to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 29, 2026.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$128Average$345FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$204Average$393FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$281Average$404FlexibilityNo cancel feeOn-time63%

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