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$109+ Cheap flights from Myrtle Beach (MYR) to Missouri

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/18. Fares are subject to change and may not be available on all flights or dates of travel.
MYR — STL
oct. 17 — oct. 241
vie. 10/17
vie. 10/24
1 adult, Economy
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Cheap flight deals from Myrtle Beach to Missouri

Keep the following information in mind while searching for Myrtle Beach to Missouri flight deals. Data was last updated septiembre 17, 2025.

Round-trip from

$259
(American Airlines)

One-way from

$109
(Expedia)

Popular in

June

Cheapest in

August

Average price

$325

Good one-way deal

$199 or less
From Myrtle Beach Intl to Missouri
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One-way flight from Myrtle Beach Intl to Missouri
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Highest demand for flights based on searches. 12% potential increase in price ($51 potential increase over avg. RT price).
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Cheapest flight prices on average. 2% potential price decrease ($7 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Price to beat on a one-way flight from Myrtle Beach Intl to Missouri.
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Find flight deals from Myrtle Beach to Missouri

Cheapest flights from Myrtle Beach to Missouri
Explore the most affordable flight options available from Myrtle Beach to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on septiembre 17, 2025.

This American Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 10/25:31 pmMYR - SGF
1 stop7h 23mAmerican Airlines
lun. 10/66:32 pmSGF - MYR
1 stop4h 27mAmerican Airlines
Deal found 9/17$259
This KAYAK deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 10/187:00 amMYR - MCI
1 stop15h 59mSpirit Airlines
lun. 10/205:15 amMCI - MYR
1 stop11h 29mSpirit Airlines
Deal found 9/15$302
This Kiwi.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 10/239:05 pmMYR - MCI
1 stop20h 11mMultiple Airlines
sáb. 10/257:02 pmMCI - MYR
2 stops12h 47mMultiple Airlines
Deal found 9/15$307
This Kiwi.com deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 10/179:05 pmMYR - STL
1 stop22h 05mMultiple Airlines
lun. 10/208:21 pmSTL - MYR
2 stops12h 06mMultiple Airlines
Deal found 9/17$312
This Kiwi.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 10/157:00 amMYR - MCI
1 stop14h 45mMultiple Airlines
mié. 10/227:02 pmMCI - MYR
2 stops43h 01mMultiple Airlines
Deal found 9/15$312
This Kiwi.com deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 12/48:30 pmMYR - STL
1 stop13h 15mMultiple Airlines
sáb. 12/62:48 pmSTL - MYR
1 stop18h 53mMultiple Airlines
Deal found 9/16$316
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 11/1312:44 pmMYR - STL
1 stop9h 35mAmerican Airlines
lun. 11/176:00 amSTL - MYR
1 stop8h 21mAmerican Airlines
Deal found 9/15$321
This Kiwi.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 10/88:14 amMYR - MCI
2 stops27h 28mMultiple Airlines
lun. 10/135:15 amMCI - MYR
1 stop27h 12mMultiple Airlines
Deal found 9/15$324
This Delta deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 10/166:58 pmMYR - STL
1 stop5h 43mDelta
mar. 10/211:30 pmSTL - MYR
1 stop3h 33mDelta
Deal found 9/15$325
This Kiwi.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 10/169:05 pmMYR - MCI
1 stop20h 11mSpirit Airlines
mar. 10/212:55 pmMCI - MYR
2 stops29h 00mSpirit Airlines
Deal found 9/15$327
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 10/118:20 pmMYR - MCI
1 stop4h 49mAmerican Airlines
sáb. 10/186:00 amMCI - MYR
1 stop11h 51mAmerican Airlines
Deal found 9/15$328
This Southwest deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 10/78:25 amMYR - STL
2 stops6h 25mSouthwest
mar. 10/149:20 amSTL - MYR
1 stop5h 15mSouthwest
Deal found 9/16$330

Cheapflights Fare Finder

 
Customize your flight search to find flights from Myrtle Beach to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated septiembre 17, 2025.
Use the filters below to find and compare flights from Myrtle Beach to Missouri that are best for you.

Fly from

Myrtle Beach

Fly to

Missouri

Route

Depart

Return

Price

Myrtle BeachKansas City

MYR - MCI

MYRMCI

Myrtle Beach Intl

sáb. 10/18

7:00 am-9:59 pm

1 stop15h 59m

Kansas City

lun. 10/20

5:15 am-5:44 pm

1 stop11h 29m

$302

Myrtle BeachKansas City

MYR - MCI

MYRMCI

Myrtle Beach Intl

jue. 10/23

9:05 pm-4:16 pm

1 stop20h 11m

Kansas City

sáb. 10/25

7:02 pm-8:49 am

2 stops12h 47m

$307

Myrtle BeachSt. Louis

MYR - STL

MYRSTL

Myrtle Beach Intl

vie. 10/17

9:05 pm-6:10 pm

1 stop22h 05m

Lambert-St Louis

lun. 10/20

8:21 pm-9:27 am

2 stops12h 06m

$312

Myrtle BeachKansas City

MYR - MCI

MYRMCI

Myrtle Beach Intl

mié. 10/15

7:00 am-8:45 pm

1 stop14h 45m

Kansas City

mié. 10/22

7:02 pm-3:03 pm

2 stops43h 01m

$312

Myrtle BeachSt. Louis

MYR - STL

MYRSTL

Myrtle Beach Intl

jue. 12/4

8:30 pm-8:45 am

1 stop13h 15m

Lambert-St Louis

sáb. 12/6

2:48 pm-10:41 am

1 stop18h 53m

$316

Myrtle BeachSt. Louis

MYR - STL

MYRSTL

Myrtle Beach Intl

jue. 11/13

12:44 pm-9:19 pm

1 stop9h 35m

Lambert-St Louis

lun. 11/17

6:00 am-3:21 pm

1 stop8h 21m

$321

Myrtle BeachSpringfield

MYR - SGF

MYRSGF

Myrtle Beach Intl

sáb. 3/7

4:00 pm-9:41 pm

1 stop6h 41m

Springfield-Branson

lun. 3/9

6:45 pm-11:35 pm

1 stop3h 50m

$321

Myrtle BeachSt. Louis

MYR - STL

MYRSTL

Myrtle Beach Intl

mié. 11/19

10:45 am-4:20 pm

1 stop6h 35m

Lambert-St Louis

jue. 11/20

8:25 am-2:15 pm

1 stop4h 50m

$325

Myrtle BeachSt. Louis

MYR - STL

MYRSTL

Myrtle Beach Intl

mar. 10/7

6:00 am-10:26 am

1 stop5h 26m

Lambert-St Louis

mar. 10/14

11:21 am-6:03 pm

1 stop5h 42m

$325

Myrtle BeachSt. Louis

MYR - STL

MYRSTL

Myrtle Beach Intl

jue. 11/6

10:36 am-4:10 pm

1 stop6h 34m

Lambert-St Louis

lun. 11/10

7:05 am-1:56 pm

1 stop5h 51m

$325

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/17

Showing 1-10 of 46 results
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Best time to book a flight from Myrtle Beach to Missouri

Have a flexible travel schedule? Discover the best time to fly to Missouri from Myrtle Beach with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Myrtle Beach to Missouri

What is the cheapest month to book a flight from Myrtle Beach to Missouri?

Currently, August is the cheapest month in which you can book a flight from Myrtle Beach to Missouri (average of $311). Flying from Myrtle Beach to Missouri in March is currently the most expensive (average of $356). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MYR to MO?

Find hourly flight availability from Myrtle Beach to Missouri. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated septiembre 17, 2025.

When flying from Myrtle Beach to Missouri, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Reviews of airlines servicing Missouri

Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated septiembre 17, 2025.
Read through reviews of airlines operating flights from Myrtle Beach to Missouri, such as Southwest, Delta, and American Airlines. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,242 reviews

Comfort

8.0

Crew

8.6

Food

7.0

Overall

8.0

Entertainment

7.5

Boarding

8.1

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Southwest
8.0
Very good
4,242 reviews
Southwest
8.0
Very good
4,242 reviews

Comfort

8.0

Crew

8.6

Food

7.0

Overall

8.0

Entertainment

7.5

Boarding

8.1

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Delta
8.0
Very good
7,961 reviews
Southwest
8.0
Very good
4,242 reviews

Comfort

8.0

Crew

8.6

Food

7.0

Overall

8.0

Entertainment

7.5

Boarding

8.1

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
American Airlines
7.2
Good
10,000 reviews
Southwest
8.0
Very good
4,242 reviews

Comfort

8.0

Crew

8.6

Food

7.0

Overall

8.0

Entertainment

7.5

Boarding

8.1

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Spirit Airlines
6.3
Okay
8,023 reviews
Southwest
8.0
Very good
4,242 reviews

Comfort

8.0

Crew

8.6

Food

7.0

Overall

8.0

Entertainment

7.5

Boarding

8.1

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines

Related info for your journey

Find useful and relevant information for your journey from Myrtle Beach to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Myrtle Beach to Missouri?

    Most people fly from Myrtle Beach Intl (MYR) if they book a flight from Myrtle Beach to Missouri. Myrtle Beach Intl is conveniently located just 2.1 mi from Myrtle Beach’s city center.

  • How popular is this Myrtle Beach to Missouri flight route?

    This flight path from Myrtle Beach Intl to Missouri was viewed by 1 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

  • How long is the flight from Myrtle Beach to Missouri?

    Spirit Airlines, American Airlines, and Delta can get you from Myrtle Beach to Missouri in just under 6h 41m. Your travel time can differ by up to 9h 18m. Airlines will cover a distance of 849 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the most popular routes from Myrtle Beach to Missouri?

    The most popular flight routes from Myrtle Beach to Missouri are Myrtle Beach Intl - Kansas City, Myrtle Beach Intl - Lambert-St Louis and Myrtle Beach Intl - Springfield-Branson.

  • What are the cheapest flights from Myrtle Beach to Missouri?

    On average you can expect to pay $317 for a flight from Myrtle Beach to Missouri. The cheapest flight overall is $173 while the most popular route, (Myrtle Beach Intl - Kansas City) is currently priced at $307.

  • Can I find deals for flights from Myrtle Beach to Missouri that include hotel bookings?

    Yes. In addition to deals on Myrtle Beach to Missouri flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Myrtle Beach to Missouri?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Myrtle Beach to Missouri.

  • Can I find deals for business class flights from Myrtle Beach to Missouri?

    Yes. Cheapflights offers flight deals from Myrtle Beach to Missouri by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Myrtle Beach to Missouri?

    Currently, August is the cheapest month in which you can book a flight from Myrtle Beach to Missouri (average of $311). Flying from Myrtle Beach to Missouri in March is currently the most expensive (average of $356). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Myrtle Beach to Missouri

See prices for flight routes from nearby airports that may be better suited for you.
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Top 4 airlines flying from Myrtle Beach to Missouri

Discover the top 4 airlines that operate flights from Myrtle Beach to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated septiembre 17, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$168Average$377FlexibilityNo cancel feeOn-timeN/A
Spirit AirlinesCheapest$199Average$246FlexibilityNo cancel feeOn-time65%
American AirlinesCheapest$204Average$439FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$281Average$394FlexibilityNo cancel feeOn-time63%

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