$49+ Cheap flights from Michigan to Missouri
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/29. Fares are subject to change and may not be available on all flights or dates of travel.
DTW — STL
Mar 31 — Apr 71
1 adult, Economy
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Find cheap flights from Michigan to Missouri with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Cheapest flights from Michigan to MissouriExplore the most affordable flight options available from Michigan to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 1, 2026.
Explore the most affordable flight options available from Michigan to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 1, 2026.
This Kiwi.com deal was found by Cheapflights users on 2/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/186:05 am
DTW
- STL
1 stop5h 32m
Multiple Airlines
Tue 3/2411:27 am
STL
- DTW
1 stop10h 10m
Multiple Airlines
Deal found 2/25![Multiple Airlines logo]()
$142
This Frontier deal was found by Cheapflights users on 2/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/152:20 pm
DTW
- STL
1 stop9h 59m
Frontier
Thu 4/1611:25 am
STL
- DTW
1 stop6h 21m
Frontier
Deal found 2/25![Frontier logo]()
$160
This Kiwi.com deal was found by Cheapflights users on 2/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/1710:27 pm
DTW
- MCI
1 stop16h 39m
Frontier
Mon 4/202:15 pm
MCI
- DTW
1 stop6h 27m
Frontier
Deal found 2/27![Frontier logo]()
$166
This Kiwi.com deal was found by Cheapflights users on 2/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/178:49 pm
DTW
- STL
1 stop11h 01m
Frontier
Mon 4/208:23 pm
STL
- DTW
1 stop14h 15m
Frontier
Deal found 2/28![Frontier logo]()
$170
This American Airlines deal was found by Cheapflights users on 2/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/278:05 am
ORD
- COU
Nonstop1h 28m
American Airlines
Mon 3/306:30 pm
COU
- ORD
Nonstop1h 35m
American Airlines
Deal found 2/26![American Airlines logo]()
$179
This Kiwi.com deal was found by Cheapflights users on 2/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/18:49 pm
DTW
- STL
1 stop11h 01m
Frontier
Mon 5/48:23 pm
STL
- DTW
1 stop14h 08m
Frontier
Deal found 2/28![Frontier logo]()
$180
This Expedia deal was found by Cheapflights users on 2/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/212:20 pm
DTW
- STL
1 stop9h 59m
Frontier
Thu 4/234:59 pm
STL
- DTW
1 stop15h 25m
Frontier
Deal found 2/25![Frontier logo]()
$181
This Priceline deal was found by Cheapflights users on 2/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/1311:54 am
DTW
- MCI
1 stop9h 04m
Frontier
Fri 4/172:15 pm
MCI
- DTW
1 stop6h 27m
Frontier
Deal found 2/27![Frontier logo]()
$181
This Kiwi.com deal was found by Cheapflights users on 2/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/186:05 am
DTW
- STL
1 stop5h 32m
Multiple Airlines
Wed 3/258:12 pm
STL
- DTW
1 stop13h 47m
Multiple Airlines
Deal found 2/25![Multiple Airlines logo]()
$185
This American Airlines deal was found by Cheapflights users on 2/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/88:00 am
ORD
- SGF
Nonstop1h 51m
American Airlines
Mon 4/135:19 am
SGF
- ORD
Nonstop1h 48m
American Airlines
Deal found 2/25![American Airlines logo]()
$189
This American Airlines deal was found by Cheapflights users on 2/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/38:40 pm
ORD
- SGF
Nonstop1h 51m
American Airlines
Sun 4/57:36 am
SGF
- ORD
Nonstop1h 51m
American Airlines
Deal found 2/27![American Airlines logo]()
$190
This CheapOair deal was found by Cheapflights users on 2/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/2411:54 am
DTW
- MCI
1 stop27h 12m
Frontier
Mon 4/272:15 pm
MCI
- DTW
1 stop6h 27m
Frontier
Deal found 2/28![Frontier logo]()
$192
Best flights from Michigan to MissouriDiscover carefully curated flight deals from Michigan to Missouri that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 1, 2026.
Discover carefully curated flight deals from Michigan to Missouri that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 1, 2026.
This United Airlines deal was found by Cheapflights users on 2/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/1710:50 pm
ORD
- COU
Nonstop1h 43m
United Airlines
Mon 4/2011:30 am
COU
- ORD
Nonstop1h 30m
United Airlines
Deal found 2/27![United Airlines logo]()
$179
This American Airlines deal was found by Cheapflights users on 2/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/126:50 pm
ORD
- COU
Nonstop1h 29m
American Airlines
Sun 3/156:30 pm
COU
- ORD
Nonstop1h 35m
American Airlines
Deal found 2/25![American Airlines logo]()
$209
This Southwest deal was found by Cheapflights users on 2/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/247:00 am
DTW
- STL
Nonstop1h 45m
Southwest
Sat 3/287:40 pm
STL
- DTW
Nonstop1h 30m
Southwest
Deal found 2/25![Southwest logo]()
$215
This Delta deal was found by Cheapflights users on 2/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/259:30 am
MDW
- MCI
1 stop5h 34m
Delta
Wed 4/12:16 pm
MCI
- MDW
1 stop3h 38m
Delta
Deal found 2/25![Delta logo]()
$231
This United Airlines deal was found by Cheapflights users on 2/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/148:50 am
ORD
- SGF
Nonstop1h 56m
United Airlines
Wed 3/1811:21 am
SGF
- ORD
Nonstop1h 49m
United Airlines
Deal found 2/27![United Airlines logo]()
$219
This American Airlines deal was found by Cheapflights users on 2/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/85:00 am
ORD
- SGF
1 stop6h 14m
American Airlines
Mon 4/135:19 am
SGF
- ORD
Nonstop1h 48m
American Airlines
Deal found 2/25![American Airlines logo]()
$232
This United Airlines deal was found by Cheapflights users on 2/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/1312:40 pm
ORD
- SGF
Nonstop1h 55m
United Airlines
Mon 3/166:08 pm
SGF
- ORD
Nonstop1h 58m
United Airlines
Deal found 2/27![United Airlines logo]()
$219
This Southwest deal was found by Cheapflights users on 2/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/37:45 am
MDW
- STL
Nonstop1h 15m
Southwest
Mon 4/65:30 am
STL
- MDW
Nonstop1h 10m
Southwest
Deal found 2/28![Southwest logo]()
$244
This Delta deal was found by Cheapflights users on 2/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/55:15 am
ORD
- STL
1 stop5h 19m
Delta
Sun 5/106:21 am
STL
- ORD
2 stops6h 40m
Delta
Deal found 2/25![Delta logo]()
$252
This United Airlines deal was found by Cheapflights users on 2/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/28:02 pm
ORD
- SGF
Nonstop2h 00m
United Airlines
Tue 5/56:00 am
SGF
- ORD
Nonstop1h 47m
United Airlines
Deal found 2/28![United Airlines logo]()
$219
This American Airlines deal was found by Cheapflights users on 2/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/101:54 pm
ORD
- SGF
1 stop8h 00m
American Airlines
Mon 4/136:05 pm
SGF
- ORD
Nonstop1h 59m
American Airlines
Deal found 2/28![American Airlines logo]()
$243
This Delta deal was found by Cheapflights users on 2/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/188:15 am
ORD
- SGF
1 stop6h 59m
Delta
Wed 4/223:59 pm
SGF
- ORD
1 stop5h 26m
Delta
Deal found 2/28![Delta logo]()
$254
This Southwest deal was found by Cheapflights users on 2/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/307:50 am
MDW
- STL
1 stop5h 20m
Southwest
Sun 5/310:00 pm
STL
- MDW
Nonstop1h 05m
Southwest
Deal found 2/28![Southwest logo]()
$254
This American Airlines deal was found by Cheapflights users on 2/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/168:15 am
ORD
- COU
Nonstop1h 31m
American Airlines
Sun 4/196:00 am
COU
- ORD
Nonstop1h 43m
American Airlines
Deal found 2/27![American Airlines logo]()
$249
This Delta deal was found by Cheapflights users on 2/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/102:32 pm
ORD
- SGF
1 stop7h 11m
Delta
Mon 4/136:55 pm
SGF
- ORD
1 stop5h 04m
Delta
Deal found 2/28![Delta logo]()
$254
This Southwest deal was found by Cheapflights users on 2/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/253:35 pm
MDW
- STL
1 stop6h 40m
Southwest
Wed 4/1510:15 am
STL
- MDW
1 stop3h 15m
Southwest
Deal found 2/25![Southwest logo]()
$264
This American Airlines deal was found by Cheapflights users on 2/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/308:43 pm
ORD
- SGF
Nonstop1h 55m
American Airlines
Sun 5/37:34 am
SGF
- ORD
Nonstop1h 56m
American Airlines
Deal found 2/28![American Airlines logo]()
$250
This United Airlines deal was found by Cheapflights users on 2/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/258:08 pm
ORD
- COU
Nonstop1h 51m
United Airlines
Tue 6/25:00 am
COU
- ORD
Nonstop1h 41m
United Airlines
Deal found 2/28![United Airlines logo]()
$254
This Delta deal was found by Cheapflights users on 2/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/31:10 pm
MDW
- STL
1 stop3h 22m
Delta
Mon 4/66:32 am
STL
- MDW
1 stop5h 57m
Delta
Deal found 2/28![Delta logo]()
$264
This United Airlines deal was found by Cheapflights users on 2/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/258:08 pm
ORD
- COU
Nonstop1h 51m
United Airlines
Sat 5/3011:23 am
COU
- ORD
Nonstop1h 42m
United Airlines
Deal found 2/28![United Airlines logo]()
$254
This Southwest deal was found by Cheapflights users on 2/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/1511:35 am
MDW
- STL
2 stops6h 20m
Southwest
Mon 4/2010:15 am
STL
- MDW
1 stop3h 50m
Southwest
Deal found 2/25![Southwest logo]()
$284
This Delta deal was found by Cheapflights users on 2/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/11:36 pm
ORD
- STL
2 stops9h 37m
Delta
Mon 5/412:23 pm
STL
- ORD
2 stops8h 17m
Delta
Deal found 2/25![Delta logo]()
$268
This American Airlines deal was found by Cheapflights users on 2/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/68:10 am
ORD
- COU
Nonstop1h 28m
American Airlines
Sun 3/86:00 am
COU
- ORD
Nonstop1h 36m
American Airlines
Deal found 2/25![American Airlines logo]()
$269
This United Airlines deal was found by Cheapflights users on 2/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/273:35 pm
ORD
- SGF
Nonstop1h 58m
United Airlines
Fri 4/36:00 am
SGF
- ORD
Nonstop1h 47m
United Airlines
Deal found 2/25![United Airlines logo]()
$260
This Delta deal was found by Cheapflights users on 2/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/69:27 am
MDW
- STL
2 stops7h 23m
Delta
Sun 5/106:45 am
STL
- MDW
1 stop5h 57m
Delta
Deal found 2/27![Delta logo]()
$269
This Southwest deal was found by Cheapflights users on 2/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/255:30 pm
MDW
- STL
1 stop5h 10m
Southwest
Sun 4/55:20 am
STL
- MDW
Nonstop1h 10m
Southwest
Deal found 2/26![Southwest logo]()
$297
This American Airlines deal was found by Cheapflights users on 2/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/66:00 am
ORD
- COU
1 stop5h 57m
American Airlines
Mon 3/96:30 pm
COU
- ORD
Nonstop1h 35m
American Airlines
Deal found 2/27![American Airlines logo]()
$278
This United Airlines deal was found by Cheapflights users on 2/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/239:00 am
ORD
- COU
Nonstop1h 33m
United Airlines
Tue 3/242:41 pm
COU
- ORD
Nonstop1h 28m
United Airlines
Deal found 2/25![United Airlines logo]()
$267
This Delta deal was found by Cheapflights users on 2/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/257:20 pm
MDW
- STL
1 stop4h 05m
Delta
Wed 4/11:39 pm
STL
- MDW
1 stop4h 15m
Delta
Deal found 2/25![Delta logo]()
$272
This Southwest deal was found by Cheapflights users on 2/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/199:55 pm
MDW
- STL
Nonstop1h 15m
Southwest
Tue 3/242:30 pm
STL
- MDW
1 stop5h 05m
Southwest
Deal found 2/28![Southwest logo]()
$304
Last-minute flights from Michigan to MissouriDiscover last-minute flight deals from Michigan to Missouri. Data last updated March 1, 2026 and is based on user searches.
Discover last-minute flight deals from Michigan to Missouri. Data last updated March 1, 2026 and is based on user searches.
This Mytrip deal was found by Cheapflights users on 2/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/105:15 am
DTW
- MCI
1 stop11h 14m
Spirit Airlines
Tue 3/2412:24 pm
MCI
- DTW
2 stops21h 48m
Spirit Airlines
Deal found 2/27![Spirit Airlines logo]()
$209
This American Airlines deal was found by Cheapflights users on 2/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/126:50 pm
ORD
- COU
Nonstop1h 29m
American Airlines
Sun 3/156:30 pm
COU
- ORD
Nonstop1h 35m
American Airlines
Deal found 2/25![American Airlines logo]()
$209
This Orbitz deal was found by Cheapflights users on 2/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/1510:27 pm
DTW
- STL
1 stop12h 22m
Frontier
Wed 3/184:51 pm
STL
- DTW
1 stop21h 03m
Frontier
Deal found 2/27![Frontier logo]()
$205
This Kiwi.com deal was found by Cheapflights users on 2/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/186:05 am
DTW
- STL
1 stop5h 32m
Multiple Airlines
Tue 3/2411:27 am
STL
- DTW
1 stop10h 10m
Multiple Airlines
Deal found 2/25![Multiple Airlines logo]()
$142
This Kiwi.com deal was found by Cheapflights users on 2/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/186:05 am
DTW
- STL
1 stop5h 32m
Multiple Airlines
Wed 3/258:12 pm
STL
- DTW
1 stop13h 47m
Multiple Airlines
Deal found 2/25![Multiple Airlines logo]()
$185
This United Airlines deal was found by Cheapflights users on 2/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/187:58 pm
ORD
- COU
Nonstop1h 35m
United Airlines
Wed 3/2511:15 am
COU
- ORD
Nonstop1h 30m
United Airlines
Deal found 2/26![United Airlines logo]()
$194
This Southwest deal was found by Cheapflights users on 2/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/187:00 am
DTW
- STL
Nonstop1h 45m
Southwest
Wed 3/256:50 pm
STL
- DTW
Nonstop1h 30m
Southwest
Deal found 2/25![Southwest logo]()
$197
This Southwest deal was found by Cheapflights users on 2/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/247:00 am
DTW
- STL
Nonstop1h 45m
Southwest
Sat 3/287:40 pm
STL
- DTW
Nonstop1h 30m
Southwest
Deal found 2/25![Southwest logo]()
$215
This Mytrip deal was found by Cheapflights users on 2/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/245:34 pm
DTW
- MCI
2 stops18h 55m
Spirit Airlines
Tue 3/3112:24 pm
MCI
- DTW
2 stops21h 48m
Spirit Airlines
Deal found 2/27![Spirit Airlines logo]()
$215
This American Airlines deal was found by Cheapflights users on 2/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/278:05 am
ORD
- COU
Nonstop1h 28m
American Airlines
Mon 3/306:30 pm
COU
- ORD
Nonstop1h 35m
American Airlines
Deal found 2/26![American Airlines logo]()
$179
This American Airlines deal was found by Cheapflights users on 2/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/273:43 pm
ORD
- SGF
Nonstop1h 47m
American Airlines
Sun 3/297:36 am
SGF
- ORD
Nonstop1h 51m
American Airlines
Deal found 2/26![American Airlines logo]()
$189
This Frontier deal was found by Cheapflights users on 2/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/305:01 am
ORD
- MCI
1 stop11h 22m
Frontier
Thu 4/3011:53 am
MCI
- ORD
1 stop10h 46m
Frontier
Deal found 2/25![Frontier logo]()
$215
One-way flights from Michigan to MissouriSearch for one-way flight options from Michigan to Missouri. Find affordable one-way fares based on user searches. Data last updated March 1, 2026.
Search for one-way flight options from Michigan to Missouri. Find affordable one-way fares based on user searches. Data last updated March 1, 2026.
This Southwest deal was found by Cheapflights users on 2/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/291:55 pm
MDW
- STL
Nonstop1h 10m
Southwest
Deal found 2/27![Southwest logo]()
$49
This United Airlines deal was found by Cheapflights users on 2/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/147:00 am
ORD
- STL
Nonstop1h 25m
United Airlines
Deal found 2/26![United Airlines logo]()
$49
This Southwest deal was found by Cheapflights users on 2/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/29:15 am
MDW
- STL
Nonstop1h 15m
Southwest
Deal found 2/27![Southwest logo]()
$59
This American Airlines deal was found by Cheapflights users on 2/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/2410:30 pm
ORD
- STL
Nonstop1h 16m
American Airlines
Deal found 2/25![American Airlines logo]()
$59
This Southwest deal was found by Cheapflights users on 2/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/163:05 pm
MDW
- STL
1 stop5h 15m
Southwest
Deal found 2/27![Southwest logo]()
$69
This Kiwi.com deal was found by Cheapflights users on 2/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/810:27 pm
DTW
- MCI
1 stop16h 39m
Frontier
Deal found 2/26![Frontier logo]()
$71
This Kiwi.com deal was found by Cheapflights users on 2/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/2410:27 pm
DTW
- STL
1 stop22h 05m
Frontier
Deal found 2/25![Frontier logo]()
$72
This Southwest deal was found by Cheapflights users on 2/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/45:40 pm
MDW
- STL
Nonstop1h 15m
Southwest
Deal found 2/28![Southwest logo]()
$72
This Kiwi.com deal was found by Cheapflights users on 2/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/110:27 pm
DTW
- MCI
1 stop16h 39m
Frontier
Deal found 2/25![Frontier logo]()
$72
This United Airlines deal was found by Cheapflights users on 3/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/281:12 pm
ORD
- STL
Nonstop1h 31m
United Airlines
Deal found 3/1![United Airlines logo]()
$72
This Kiwi.com deal was found by Cheapflights users on 2/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/1710:27 pm
DTW
- STL
1 stop22h 05m
Frontier
Deal found 2/25![Frontier logo]()
$74
This Southwest deal was found by Cheapflights users on 2/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/142:40 pm
ORD
- STL
1 stop8h 35m
Southwest
Deal found 2/26![Southwest logo]()
$74
Find flight deals from Michigan to Missouri
Keep the following information in mind while searching for Michigan to Missouri flight deals. Data was last updated March 1, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $159 (Kiwi.com) |
One-way from | $49 (Southwest) |
Popular in | February |
Cheapest in | August |
Average price | $328 |
Good round-trip deal | $319 or less |
Good one-way deal | $175 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Michigan to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 1, 2026.
Use the filters below to find and compare flights from Michigan to Missouri that are best for you.
Fly from
Fly to
Route
Depart
Return
ChicagoColumbia
ORD - COU
ORDCOU
Chicago O'Hare Intl
Fri 4/17
10:50 pm-12:33 am
Nonstop1h 43m
Columbia Regional
Mon 4/20
11:30 am-1:00 pm
Nonstop1h 30m
$179
ChicagoColumbia
ORD - COU
ORDCOU
Chicago O'Hare Intl
Thu 3/12
6:50 pm-8:19 pm
Nonstop1h 29m
Columbia Regional
Sun 3/15
6:30 pm-8:05 pm
Nonstop1h 35m
$209
DetroitSt. Louis
DTW - STL
DTWSTL
Detroit Metropolitan Wayne County
Tue 3/24
7:00 am-7:45 am
Nonstop1h 45m
Lambert-St Louis
Sat 3/28
7:40 pm-10:10 pm
Nonstop1h 30m
$215
ChicagoSpringfield
ORD - SGF
ORDSGF
Chicago O'Hare Intl
Sat 3/14
8:50 am-10:46 am
Nonstop1h 56m
Springfield-Branson
Wed 3/18
11:21 am-1:10 pm
Nonstop1h 49m
$219
ChicagoSpringfield
ORD - SGF
ORDSGF
Chicago O'Hare Intl
Fri 3/13
12:40 pm-2:35 pm
Nonstop1h 55m
Springfield-Branson
Mon 3/16
6:08 pm-8:06 pm
Nonstop1h 58m
$219
ChicagoSpringfield
ORD - SGF
ORDSGF
Chicago O'Hare Intl
Sat 5/2
8:02 pm-10:02 pm
Nonstop2h 00m
Springfield-Branson
Tue 5/5
6:00 am-7:47 am
Nonstop1h 47m
$219
ChicagoKansas City
MDW - MCI
MDWMCI
Chicago Midway
Wed 3/25
9:30 am-3:04 pm
1 stop5h 34m
Kansas City
Wed 4/1
2:16 pm-5:54 pm
1 stop3h 38m
$231
ChicagoSpringfield
ORD - SGF
ORDSGF
Chicago O'Hare Intl
Wed 4/8
5:00 am-11:14 am
1 stop6h 14m
Springfield-Branson
Mon 4/13
5:19 am-7:07 am
Nonstop1h 48m
$232
ChicagoSpringfield
ORD - SGF
ORDSGF
Chicago O'Hare Intl
Fri 4/10
1:54 pm-9:54 pm
1 stop8h 00m
Springfield-Branson
Mon 4/13
6:05 pm-8:04 pm
Nonstop1h 59m
$243
ChicagoSt. Louis
MDW - STL
MDWSTL
Chicago Midway
Fri 4/3
7:45 am-9:00 am
Nonstop1h 15m
Lambert-St Louis
Mon 4/6
5:30 am-6:40 am
Nonstop1h 10m
$244
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from Michigan to Missouri
Have a flexible travel schedule? Discover the best time to fly to Missouri from Michigan with our price prediction graph.
MDW-STL
ORD-STL
GRR-MCI
ORD-MCI
DTW-MCI
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Michigan to Missouri
USMI-USMO
MDW-STL
ORD-STL
GRR-MCI
ORD-MCI
What is the cheapest month to book a flight from Michigan to Missouri?
Currently, August is the cheapest month in which you can book a flight from Michigan to Missouri (average of $40). Flying from Michigan to Missouri in January is currently the most expensive (average of $253). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from MI to MO?
Find hourly flight availability from Michigan to Missouri. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated March 1, 2026.
It’s typically best to fly out from Michigan to Missouri at noon. Doing so could potentially save you 20% on the flight price compared to flying in the afternoon, which is usually more expensive.
What is the cheapest day to fly from Michigan to Missouri?
Use this chart to determine the cheapest time to fly round-trip from Michigan to Missouri. Price data was last updated on February 21, 2026.
Travelers seeking maximum savings on their Michigan to Missouri flight should consider departing on Sunday at noon when fares are most often at their lowest. Monday afternoons flights should be avoided if possible as fares are typically the most expensive at this time.
Weekly flight availability from Michigan to Missouri
Explore weekly flight availability from Michigan to Missouri. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated March 1, 2026.
The most flights from USMI to USMO are scheduled on a Friday (13 on average). You will have fewer flight options on Tuesday, which is when the least amount of flights are scheduled (10 on average).
Reviews of airlines servicing Missouri
Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated March 1, 2026.
Peruse reviews from past customers who have flown with Southwest, Delta, and United Airlines from Michigan to Missouri to help guide your decision. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Overall
8.0
Crew
8.6
Boarding
8.1
Food
7.0
Entertainment
7.5
Comfort
8.0
Reviews
1 / 20
8.0
ExcellentAnonymous,Feb 2026
DEN - BDL
Overall
8.0
Crew
8.6
Boarding
8.1
Food
7.0
Entertainment
7.5
Comfort
8.0
Reviews
1 / 20
8.0
ExcellentAnonymous,Feb 2026
DEN - BDL
Overall
8.0
Crew
8.6
Boarding
8.1
Food
7.0
Entertainment
7.5
Comfort
8.0
Reviews
1 / 20
8.0
ExcellentAnonymous,Feb 2026
DEN - BDL
Overall
8.0
Crew
8.6
Boarding
8.1
Food
7.0
Entertainment
7.5
Comfort
8.0
Reviews
1 / 20
8.0
ExcellentAnonymous,Feb 2026
DEN - BDL
Overall
8.0
Crew
8.6
Boarding
8.1
Food
7.0
Entertainment
7.5
Comfort
8.0
Reviews
1 / 20
8.0
ExcellentAnonymous,Feb 2026
DEN - BDL
Overall
8.0
Crew
8.6
Boarding
8.1
Food
7.0
Entertainment
7.5
Comfort
8.0
Reviews
1 / 20
8.0
ExcellentAnonymous,Feb 2026
DEN - BDL
Related info for your journey
Find useful and relevant information for your journey from Michigan to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Michigan to Missouri
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Missouri by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Michigan to Missouri by cabin class
Find flights from Michigan to Missouri, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Michigan and Missouri flights
Browse other Michigan and Missouri flight options. Last updated on March 1, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Find a return flight route from Missouri
Find the right flight back to Michigan after your stay in Missouri
Michigan to Missouri flights
Consider these flights traveling from Michigan to Missouri.
Top 6 airlines flying from Michigan to Missouri
Discover the top 6 airlines that operate flights from Michigan to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 1, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$28 | Average$138 | FlexibilityNo cancel fee | On-time65% | |
| Cheapest$111 | Average$228 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$121 | Average$393 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$121 | Average$358 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$199 | Average$358 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$228 | Average$399 | FlexibilityNo cancel fee | On-time69% |