$49+ Cheap flights from Michigan to Missouri
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/3. Fares are subject to change and may not be available on all flights or dates of travel.
DTW — STL
Apr 12 — Apr 191
Round-trip
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from Michigan to Missouri with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Michigan to Missouri
Cheapest
Best
Last-minute
One-way
Cheapest flights from Michigan to MissouriExplore the most affordable flight options available from Michigan to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 13, 2026.
Explore the most affordable flight options available from Michigan to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 13, 2026.
This Kiwi.com deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/125:09 pm
DTW
- STL
1 stop14h 41m
Frontier
Mon 5/188:13 pm
STL
- DTW
1 stop14h 18m
Frontier
Deal found 3/9![Frontier logo]()
$146
This Frontier deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/143:50 pm
DTW
- STL
1 stop8h 29m
Frontier
Wed 4/158:23 pm
STL
- DTW
1 stop11h 42m
Frontier
Deal found 3/8![Frontier logo]()
$160
This Kiwi.com deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/217:04 pm
DTW
- STL
1 stop12h 46m
Frontier
Mon 4/278:23 pm
STL
- DTW
1 stop20h 44m
Frontier
Deal found 3/9![Frontier logo]()
$162
This Priceline deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/97:55 am
DTW
- MCI
1 stop6h 54m
Frontier
Fri 5/152:34 pm
MCI
- DTW
1 stop8h 25m
Frontier
Deal found 3/11![Frontier logo]()
$180
This Kiwi.com deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/139:50 pm
DTW
- STL
2 stops34h 00m
Multiple Airlines
Thu 4/2311:25 am
STL
- DTW
1 stop6h 21m
Multiple Airlines
Deal found 3/12![Multiple Airlines logo]()
$185
This Gotogate deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/121:31 pm
DTW
- STL
1 stop5h 02m
Frontier
Thu 5/144:19 pm
STL
- DTW
1 stop18h 41m
Frontier
Deal found 3/13![Frontier logo]()
$189
This Southwest deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/17:15 pm
DTW
- STL
Nonstop1h 40m
Southwest
Wed 4/86:45 pm
STL
- DTW
Nonstop1h 30m
Southwest
Deal found 3/11![Southwest logo]()
$197
This Kiwi.com deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/810:27 pm
DTW
- MCI
1 stop16h 39m
Frontier
Thu 5/1411:13 am
MCI
- DTW
1 stop20h 57m
Frontier
Deal found 3/9![Frontier logo]()
$197
This American Airlines deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/26:50 pm
ORD
- COU
Nonstop1h 29m
American Airlines
Sun 4/510:08 am
COU
- ORD
Nonstop1h 29m
American Airlines
Deal found 3/9![American Airlines logo]()
$198
This United Airlines deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/68:18 pm
ORD
- COU
Nonstop1h 43m
United Airlines
Mon 4/135:00 am
COU
- ORD
Nonstop1h 30m
United Airlines
Deal found 3/8![United Airlines logo]()
$199
This Expedia deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/168:43 pm
DTW
- STL
1 stop11h 07m
Frontier
Sat 4/188:23 pm
STL
- DTW
1 stop11h 42m
Frontier
Deal found 3/11![Frontier logo]()
$201
This Trip.com deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/47:23 pm
GRR
- STL
1 stop28h 56m
Frontier
Wed 5/64:55 pm
STL
- GRR
1 stop18h 32m
Frontier
Deal found 3/10![Frontier logo]()
$201
Best flights from Michigan to MissouriDiscover carefully curated flight deals from Michigan to Missouri that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 13, 2026.
Discover carefully curated flight deals from Michigan to Missouri that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 13, 2026.
This United Airlines deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/149:16 am
ORD
- COU
Nonstop1h 39m
United Airlines
Mon 8/1711:30 am
COU
- ORD
Nonstop1h 43m
United Airlines
Deal found 3/8![United Airlines logo]()
$199
This Southwest deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/147:00 am
DTW
- STL
Nonstop1h 45m
Southwest
Mon 5/187:40 pm
STL
- DTW
Nonstop1h 30m
Southwest
Deal found 3/10![Southwest logo]()
$215
This American Airlines deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/302:27 pm
ORD
- COU
Nonstop1h 31m
American Airlines
Sun 5/36:00 am
COU
- ORD
Nonstop1h 43m
American Airlines
Deal found 3/13![American Airlines logo]()
$219
This Delta deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/278:15 am
ORD
- SGF
1 stop6h 30m
Delta
Sun 8/306:00 am
SGF
- ORD
1 stop6h 08m
Delta
Deal found 3/10![Delta logo]()
$249
This United Airlines deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/134:10 pm
ORD
- COU
Nonstop1h 35m
United Airlines
Sun 8/163:05 pm
COU
- ORD
Nonstop1h 43m
United Airlines
Deal found 3/9![United Airlines logo]()
$199
This American Airlines deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/29:20 am
ORD
- COU
1 stop7h 47m
American Airlines
Sun 4/510:08 am
COU
- ORD
Nonstop1h 29m
American Airlines
Deal found 3/9![American Airlines logo]()
$223
This Southwest deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/243:00 pm
DTW
- STL
1 stop8h 05m
Southwest
Tue 4/286:45 pm
STL
- DTW
Nonstop1h 30m
Southwest
Deal found 3/9![Southwest logo]()
$229
This United Airlines deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/78:09 pm
ORD
- SGF
Nonstop1h 55m
United Airlines
Tue 4/146:50 pm
SGF
- ORD
Nonstop1h 48m
United Airlines
Deal found 3/8![United Airlines logo]()
$209
This Delta deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/89:40 am
ORD
- SGF
1 stop5h 30m
Delta
Mon 4/136:55 pm
SGF
- ORD
1 stop5h 04m
Delta
Deal found 3/11![Delta logo]()
$249
This United Airlines deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/298:04 pm
ORD
- SGF
Nonstop1h 55m
United Airlines
Sat 4/46:50 pm
SGF
- ORD
Nonstop1h 48m
United Airlines
Deal found 3/8![United Airlines logo]()
$209
This Southwest deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/185:50 am
DTW
- STL
2 stops8h 45m
Southwest
Sat 5/1610:35 am
STL
- DTW
Nonstop1h 30m
Southwest
Deal found 3/12![Southwest logo]()
$230
This American Airlines deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/266:50 pm
ORD
- COU
Nonstop1h 29m
American Airlines
Sun 4/510:08 am
COU
- ORD
Nonstop1h 29m
American Airlines
Deal found 3/10![American Airlines logo]()
$234
This Southwest deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/1211:35 am
MDW
- STL
2 stops6h 20m
Southwest
Fri 5/158:25 am
STL
- MDW
2 stops6h 30m
Southwest
Deal found 3/9![Southwest logo]()
$237
This United Airlines deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/48:08 pm
ORD
- COU
Nonstop1h 51m
United Airlines
Sun 6/78:00 am
COU
- ORD
Nonstop1h 40m
United Airlines
Deal found 3/10![United Airlines logo]()
$219
This American Airlines deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/92:27 pm
ORD
- COU
Nonstop1h 31m
American Airlines
Mon 4/135:21 pm
COU
- ORD
1 stop5h 24m
American Airlines
Deal found 3/12![American Airlines logo]()
$243
This Delta deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/3012:10 pm
ORD
- SGF
1 stop6h 00m
Delta
Sun 8/26:45 pm
SGF
- ORD
1 stop5h 10m
Delta
Deal found 3/9![Delta logo]()
$269
This Southwest deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/2612:20 pm
MDW
- MCI
Nonstop1h 30m
Southwest
Thu 5/285:30 am
MCI
- MDW
Nonstop1h 25m
Southwest
Deal found 3/12![Southwest logo]()
$238
This United Airlines deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/89:15 am
ORD
- COU
Nonstop1h 40m
United Airlines
Mon 4/135:00 am
COU
- ORD
Nonstop1h 30m
United Airlines
Deal found 3/11![United Airlines logo]()
$219
This Delta deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/11:36 pm
ORD
- STL
2 stops9h 37m
Delta
Mon 5/411:42 am
STL
- ORD
1 stop6h 53m
Delta
Deal found 3/11![Delta logo]()
$279
This American Airlines deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/305:00 am
ORD
- SGF
1 stop6h 29m
American Airlines
Sun 5/37:34 am
SGF
- ORD
Nonstop1h 56m
American Airlines
Deal found 3/13![American Airlines logo]()
$254
This Southwest deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/68:25 pm
DTW
- STL
1 stop4h 05m
Southwest
Mon 4/131:45 pm
STL
- DTW
2 stops7h 35m
Southwest
Deal found 3/8![Southwest logo]()
$240
This United Airlines deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/81:16 pm
ORD
- COU
Nonstop1h 32m
United Airlines
Sat 4/115:00 am
COU
- ORD
Nonstop1h 27m
United Airlines
Deal found 3/11![United Airlines logo]()
$219
This Delta deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/282:00 pm
ORD
- STL
2 stops9h 21m
Delta
Mon 6/17:01 pm
STL
- ORD
1 stop4h 58m
Delta
Deal found 3/11![Delta logo]()
$279
This Southwest deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/95:50 am
DTW
- STL
1 stop5h 10m
Southwest
Sat 5/92:05 pm
STL
- DTW
2 stops6h 20m
Southwest
Deal found 3/9![Southwest logo]()
$240
This United Airlines deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/99:15 am
ORD
- COU
Nonstop1h 40m
United Airlines
Tue 4/148:00 am
COU
- ORD
Nonstop1h 30m
United Airlines
Deal found 3/12![United Airlines logo]()
$219
This Delta deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/311:57 pm
ORD
- MCI
2 stops10h 15m
Delta
Sat 4/410:37 am
MCI
- ORD
1 stop5h 41m
Delta
Deal found 3/10![Delta logo]()
$283
This United Airlines deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/71:16 pm
ORD
- COU
Nonstop1h 32m
United Airlines
Tue 4/145:00 am
COU
- ORD
Nonstop1h 30m
United Airlines
Deal found 3/12![United Airlines logo]()
$219
This Southwest deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/811:35 am
MDW
- STL
2 stops6h 20m
Southwest
Wed 4/151:15 pm
STL
- MDW
2 stops6h 20m
Southwest
Deal found 3/10![Southwest logo]()
$243
This Delta deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/29:35 am
MDW
- STL
1 stop3h 23m
Delta
Sun 4/56:32 am
STL
- MDW
1 stop5h 57m
Delta
Deal found 3/12![Delta logo]()
$285
This Southwest deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/49:30 pm
MDW
- MCI
Nonstop1h 30m
Southwest
Wed 5/62:10 pm
MCI
- MDW
1 stop3h 00m
Southwest
Deal found 3/12![Southwest logo]()
$244
Last-minute flights from Michigan to MissouriDiscover last-minute flight deals from Michigan to Missouri. Data last updated March 13, 2026 and is based on user searches.
Discover last-minute flight deals from Michigan to Missouri. Data last updated March 13, 2026 and is based on user searches.
This Southwest deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/17:15 pm
DTW
- STL
Nonstop1h 40m
Southwest
Wed 4/86:45 pm
STL
- DTW
Nonstop1h 30m
Southwest
Deal found 3/11![Southwest logo]()
$197
This Kiwi.com deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/15:55 pm
DTW
- STL
1 stop24h 39m
Frontier
Wed 4/88:16 pm
STL
- DTW
1 stop13h 42m
Frontier
Deal found 3/11![Frontier logo]()
$209
This American Airlines deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/26:50 pm
ORD
- COU
Nonstop1h 29m
American Airlines
Sun 4/510:08 am
COU
- ORD
Nonstop1h 29m
American Airlines
Deal found 3/9![American Airlines logo]()
$198
This United Airlines deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/68:18 pm
ORD
- COU
Nonstop1h 43m
United Airlines
Mon 4/135:00 am
COU
- ORD
Nonstop1h 30m
United Airlines
Deal found 3/8![United Airlines logo]()
$199
This Kiwi.com deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/65:50 pm
DTW
- STL
1 stop17h 40m
Frontier
Thu 4/96:29 pm
STL
- DTW
1 stop12h 33m
Frontier
Deal found 3/10![Frontier logo]()
$203
This Priceline deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/911:54 am
DTW
- MCI
1 stop9h 07m
Frontier
Thu 4/1611:53 am
MCI
- DTW
1 stop5h 53m
Frontier
Deal found 3/12![Frontier logo]()
$201
This Kiwi.com deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/139:50 pm
DTW
- STL
2 stops34h 00m
Multiple Airlines
Thu 4/2311:25 am
STL
- DTW
1 stop6h 21m
Multiple Airlines
Deal found 3/12![Multiple Airlines logo]()
$185
This Frontier deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/143:50 pm
DTW
- STL
1 stop8h 29m
Frontier
Wed 4/158:23 pm
STL
- DTW
1 stop11h 42m
Frontier
Deal found 3/8![Frontier logo]()
$160
This Expedia deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/168:43 pm
DTW
- STL
1 stop11h 07m
Frontier
Sat 4/188:23 pm
STL
- DTW
1 stop11h 42m
Frontier
Deal found 3/11![Frontier logo]()
$201
This Southwest deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/208:15 pm
DTW
- STL
Nonstop1h 40m
Southwest
Wed 4/226:45 pm
STL
- DTW
Nonstop1h 30m
Southwest
Deal found 3/10![Southwest logo]()
$206
This Kiwi.com deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/217:04 pm
DTW
- STL
1 stop12h 46m
Frontier
Mon 4/278:23 pm
STL
- DTW
1 stop20h 44m
Frontier
Deal found 3/9![Frontier logo]()
$162
This Kiwi.com deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/238:43 pm
DTW
- STL
1 stop11h 07m
Frontier
Mon 4/278:23 pm
STL
- DTW
1 stop14h 15m
Frontier
Deal found 3/11![Frontier logo]()
$208
One-way flights from Michigan to MissouriSearch for one-way flight options from Michigan to Missouri. Find affordable one-way fares based on user searches. Data last updated March 13, 2026.
Search for one-way flight options from Michigan to Missouri. Find affordable one-way fares based on user searches. Data last updated March 13, 2026.
This Southwest deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/121:55 pm
MDW
- STL
Nonstop1h 10m
Southwest
Deal found 3/10![Southwest logo]()
$49
This United Airlines deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/77:45 pm
ORD
- STL
Nonstop1h 28m
United Airlines
Deal found 3/9![United Airlines logo]()
$49
This Southwest deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/312:40 pm
ORD
- STL
1 stop5h 15m
Southwest
Deal found 3/9![Southwest logo]()
$59
This Southwest deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/222:40 pm
ORD
- STL
1 stop7h 20m
Southwest
Deal found 3/10![Southwest logo]()
$64
This American Airlines deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/148:55 pm
ORD
- STL
Nonstop1h 24m
American Airlines
Deal found 3/10![American Airlines logo]()
$66
This Kiwi.com deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/287:04 pm
DTW
- STL
1 stop12h 46m
Frontier
Deal found 3/10![Frontier logo]()
$69
This Kiwi.com deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/1212:26 pm
DTW
- STL
1 stop19h 24m
Frontier
Deal found 3/10![Frontier logo]()
$70
This Kiwi.com deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/126:00 am
MDW
- STL
1 stop24h 50m
Frontier
Deal found 3/10![Frontier logo]()
$70
This Southwest deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/1612:45 pm
MDW
- STL
Nonstop1h 15m
Southwest
Deal found 3/9![Southwest logo]()
$72
This Kiwi.com deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/146:10 am
MDW
- STL
1 stop24h 40m
Frontier
Deal found 3/12![Frontier logo]()
$76
This Kiwi.com deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/126:55 am
ORD
- STL
1 stop26h 00m
Frontier
Deal found 3/12![Frontier logo]()
$76
This Kiwi.com deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/147:04 pm
DTW
- STL
1 stop12h 46m
Frontier
Deal found 3/10![Frontier logo]()
$78
Find flight deals from Michigan to Missouri
Keep the following information in mind while searching for Michigan to Missouri flight deals. Data was last updated March 13, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $146 (Kiwi.com) |
One-way from | $49 (Southwest) |
Popular in | February |
Cheapest in | August |
Average price | $339 |
Good round-trip deal | $366 or less |
Good one-way deal | $179 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Michigan to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 13, 2026.
Use the filters below to find and compare flights from Michigan to Missouri that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
ChicagoColumbia
ORD - COU
ORDCOU
Chicago O'Hare Intl
Fri 8/14
9:16 am-10:55 am
Nonstop1h 39m
Columbia Regional
Mon 8/17
11:30 am-1:13 pm
Nonstop1h 43m
$199
ChicagoColumbia
ORD - COU
ORDCOU
Chicago O'Hare Intl
Thu 8/13
4:10 pm-5:45 pm
Nonstop1h 35m
Columbia Regional
Sun 8/16
3:05 pm-4:48 pm
Nonstop1h 43m
$199
ChicagoSpringfield
ORD - SGF
ORDSGF
Chicago O'Hare Intl
Tue 4/7
8:09 pm-10:04 pm
Nonstop1h 55m
Springfield-Branson
Tue 4/14
6:50 pm-8:38 pm
Nonstop1h 48m
$209
ChicagoSpringfield
ORD - SGF
ORDSGF
Chicago O'Hare Intl
Sun 3/29
8:04 pm-9:59 pm
Nonstop1h 55m
Springfield-Branson
Sat 4/4
6:50 pm-8:38 pm
Nonstop1h 48m
$209
DetroitSt. Louis
DTW - STL
DTWSTL
Detroit Metropolitan Wayne County
Thu 5/14
7:00 am-7:45 am
Nonstop1h 45m
Lambert-St Louis
Mon 5/18
7:40 pm-10:10 pm
Nonstop1h 30m
$215
ChicagoColumbia
ORD - COU
ORDCOU
Chicago O'Hare Intl
Thu 4/30
2:27 pm-3:58 pm
Nonstop1h 31m
Columbia Regional
Sun 5/3
6:00 am-7:43 am
Nonstop1h 43m
$219
ChicagoColumbia
ORD - COU
ORDCOU
Chicago O'Hare Intl
Thu 6/4
8:08 pm-9:59 pm
Nonstop1h 51m
Columbia Regional
Sun 6/7
8:00 am-9:40 am
Nonstop1h 40m
$219
ChicagoColumbia
ORD - COU
ORDCOU
Chicago O'Hare Intl
Wed 4/8
9:15 am-10:55 am
Nonstop1h 40m
Columbia Regional
Mon 4/13
5:00 am-6:30 am
Nonstop1h 30m
$219
ChicagoColumbia
ORD - COU
ORDCOU
Chicago O'Hare Intl
Wed 4/8
1:16 pm-2:48 pm
Nonstop1h 32m
Columbia Regional
Sat 4/11
5:00 am-6:27 am
Nonstop1h 27m
$219
ChicagoColumbia
ORD - COU
ORDCOU
Chicago O'Hare Intl
Thu 4/9
9:15 am-10:55 am
Nonstop1h 40m
Columbia Regional
Tue 4/14
8:00 am-9:30 am
Nonstop1h 30m
$219
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from Michigan to Missouri
Have a flexible travel schedule? Discover the best time to fly to Missouri from Michigan with our price prediction graph.
ORD-COU
DTW-STL
ORD-SGF
MDW-STL
MDW-MCI
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Michigan to Missouri
USMI-USMO
ORD-COU
DTW-STL
ORD-SGF
MDW-STL
What is the cheapest month to book a flight from Michigan to Missouri?
Currently, August is the cheapest month in which you can book a flight from Michigan to Missouri (average of $39). Flying from Michigan to Missouri in January is currently the most expensive (average of $253). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from MI to MO?
Find hourly flight availability from Michigan to Missouri. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated March 13, 2026.
It’s typically best to fly out from Michigan to Missouri at noon. Doing so could potentially save you 20% on the flight price compared to flying in the afternoon, which is usually more expensive.
What is the cheapest day to fly from Michigan to Missouri?
Use this chart to determine the cheapest time to fly round-trip from Michigan to Missouri. Price data was last updated on March 12, 2026.
Travelers seeking maximum savings on their Michigan to Missouri flight should consider departing on Sunday at noon when fares are most often at their lowest. Monday afternoons flights should be avoided if possible as fares are typically the most expensive at this time.
Weekly flight availability from Michigan to Missouri
Explore weekly flight availability from Michigan to Missouri. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated March 13, 2026.
The most flights from USMI to USMO are scheduled on a Thursday (16 on average). You will have fewer flight options on Saturday, which is when the least amount of flights are scheduled (5 on average).
Reviews of airlines servicing Missouri
Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated March 13, 2026.
Peruse reviews from past customers who have flown with Southwest,Delta, andUnited Airlines from Michigan to Missouri to help guide your decision. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Comfort
8.0
Food
7.0
Crew
8.6
Boarding
8.1
Entertainment
7.5
Overall
8.0
Reviews
1 / 20
10.0
ExcellentAnonymous,Mar 2026
KOA - HNL
Comfort
8.0
Food
7.0
Crew
8.6
Boarding
8.1
Entertainment
7.5
Overall
8.0
Reviews
1 / 20
10.0
ExcellentAnonymous,Mar 2026
KOA - HNL
Comfort
8.0
Food
7.0
Crew
8.6
Boarding
8.1
Entertainment
7.5
Overall
8.0
Reviews
1 / 20
10.0
ExcellentAnonymous,Mar 2026
KOA - HNL
Comfort
8.0
Food
7.0
Crew
8.6
Boarding
8.1
Entertainment
7.5
Overall
8.0
Reviews
1 / 20
10.0
ExcellentAnonymous,Mar 2026
KOA - HNL
Comfort
8.0
Food
7.0
Crew
8.6
Boarding
8.1
Entertainment
7.5
Overall
8.0
Reviews
1 / 20
10.0
ExcellentAnonymous,Mar 2026
KOA - HNL
Comfort
8.0
Food
7.0
Crew
8.6
Boarding
8.1
Entertainment
7.5
Overall
8.0
Reviews
1 / 20
10.0
ExcellentAnonymous,Mar 2026
KOA - HNL
Related info for your journey
Find useful and relevant information for your journey from Michigan to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Complete your trip
Flights by cabin class
Other flight options
Popular flights
Return Flight Options
Top destinations
Alternative routes for Michigan to Missouri
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Missouri by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Michigan to Missouri by cabin class
Find flights from Michigan to Missouri, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Michigan and Missouri flights
Browse other Michigan and Missouri flight options. Last updated on March 13, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Find a return flight route from Missouri
Find the right flight back to Michigan after your stay in Missouri
Michigan to Missouri flights
Consider these flights traveling from Michigan to Missouri.
Top 6 airlines flying from Michigan to Missouri
Discover the top 6 airlines that operate flights from Michigan to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 13, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$28 | Average$138 | FlexibilityNo cancel fee | On-time65% | |
| Cheapest$111 | Average$228 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$120 | Average$348 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$121 | Average$383 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$199 | Average$360 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$228 | Average$401 | FlexibilityNo cancel fee | On-time69% |