$63+ Cheap flights from Michigan to Missouri
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/3. Fares are subject to change and may not be available on all flights or dates of travel.
DTW — STL
Jun 5 — Jun 121
Round-trip
1 adult, Economy
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Cheapest flights from Michigan to MissouriExplore the most affordable flight options available from Michigan to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 6, 2026.
Explore the most affordable flight options available from Michigan to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 6, 2026.
This Kiwi.com deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/46:50 am
DTW
- STL
1 stop11h 43m
Frontier
Tue 6/96:31 pm
STL
- DTW
1 stop21h 22m
Frontier
Deal found 5/5![Frontier logo]()
$124
This Kiwi.com deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/41:59 pm
DTW
- STL
1 stop19h 56m
Frontier
Mon 6/85:27 pm
STL
- DTW
1 stop23h 32m
Frontier
Deal found 5/5![Frontier logo]()
$125
This Kiwi.com deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/36:20 am
DTW
- MCI
1 stop12h 09m
Frontier
Mon 6/86:24 pm
MCI
- DTW
1 stop22h 35m
Frontier
Deal found 5/4![Frontier logo]()
$126
This Kiwi.com deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/296:05 pm
DTW
- STL
1 stop15h 50m
Frontier
Fri 6/55:27 pm
STL
- DTW
1 stop6h 12m
Frontier
Deal found 5/1![Frontier logo]()
$132
This Kiwi.com deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/286:50 am
DTW
- STL
1 stop11h 43m
Frontier
Mon 6/15:27 pm
STL
- DTW
1 stop6h 12m
Frontier
Deal found 5/4![Frontier logo]()
$134
This Kiwi.com deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/46:30 am
DTW
- STL
1 stop12h 03m
Multiple Airlines
Fri 6/55:27 pm
STL
- DTW
1 stop6h 12m
Multiple Airlines
Deal found 5/1![Multiple Airlines logo]()
$137
This Kiwi.com deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/105:38 pm
DTW
- STL
1 stop24h 59m
Frontier
Fri 8/144:52 pm
STL
- DTW
1 stop19h 52m
Frontier
Deal found 5/5![Frontier logo]()
$152
This Kiwi.com deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/296:05 pm
DTW
- STL
1 stop15h 50m
Frontier
Mon 6/15:27 pm
STL
- DTW
1 stop6h 12m
Frontier
Deal found 5/3![Frontier logo]()
$155
This Kiwi.com deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/126:10 am
DTW
- MCI
1 stop12h 11m
Frontier
Mon 6/156:16 pm
MCI
- DTW
1 stop17h 51m
Frontier
Deal found 5/5![Frontier logo]()
$155
This Kiwi.com deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/256:45 am
DTW
- STL
1 stop27h 07m
Frontier
Tue 9/16:33 pm
STL
- DTW
1 stop5h 09m
Frontier
Deal found 5/3![Frontier logo]()
$156
This Kiwi.com deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/252:02 pm
DTW
- MCI
1 stop28h 19m
Frontier
Mon 6/296:16 pm
MCI
- DTW
2 stops16h 19m
Frontier
Deal found 5/5![Frontier logo]()
$156
This Kiwi.com deal was found by Cheapflights users on 5/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/16:05 pm
DTW
- STL
1 stop24h 28m
Frontier
Thu 6/46:33 pm
STL
- DTW
1 stop5h 05m
Frontier
Deal found 5/2![Frontier logo]()
$158
Best flights from Michigan to MissouriDiscover carefully curated flight deals from Michigan to Missouri that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 6, 2026.
Discover carefully curated flight deals from Michigan to Missouri that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 6, 2026.
This Delta deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/212:31 pm
DTW
- STL
Nonstop1h 39m
Delta
Tue 6/96:30 am
STL
- DTW
Nonstop1h 34m
Delta
Deal found 5/3![Delta logo]()
$197
This Southwest deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/48:15 pm
DTW
- STL
Nonstop1h 35m
Southwest
Tue 6/97:40 pm
STL
- DTW
Nonstop1h 30m
Southwest
Deal found 5/5![Southwest logo]()
$211
This United Airlines deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/308:45 am
ORD
- COU
Nonstop1h 33m
United Airlines
Mon 6/18:00 am
COU
- ORD
Nonstop1h 40m
United Airlines
Deal found 5/3![United Airlines logo]()
$239
This American Airlines deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/45:59 am
ORD
- COU
1 stop5h 15m
American Airlines
Sun 6/76:47 pm
COU
- ORD
Nonstop1h 47m
American Airlines
Deal found 5/6![American Airlines logo]()
$248
This Kiwi.com deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/59:23 pm
MDW
- SGF
1 stop11h 30m
Allegiant Air
Thu 6/118:10 pm
SGF
- MDW
2 stops23h 20m
Allegiant Air
Deal found 5/3![Allegiant Air logo]()
$464
This Southwest deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/2712:40 pm
DTW
- STL
2 stops8h 20m
Southwest
Tue 6/22:30 pm
STL
- DTW
2 stops7h 00m
Southwest
Deal found 5/1![Southwest logo]()
$235
This United Airlines deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/1010:00 pm
ORD
- COU
Nonstop1h 33m
United Airlines
Sat 7/118:00 am
COU
- ORD
Nonstop1h 40m
United Airlines
Deal found 5/1![United Airlines logo]()
$239
This Delta deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/146:00 am
MDW
- STL
1 stop6h 34m
Delta
Tue 6/167:08 am
STL
- MDW
1 stop4h 57m
Delta
Deal found 5/3![Delta logo]()
$257
This American Airlines deal was found by Cheapflights users on 5/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/24:45 pm
ORD
- COU
1 stop6h 01m
American Airlines
Tue 7/75:19 pm
COU
- ORD
1 stop7h 24m
American Airlines
Deal found 5/2![American Airlines logo]()
$258
This Southwest deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/18:30 pm
DTW
- STL
1 stop3h 15m
Southwest
Tue 6/211:35 am
STL
- DTW
2 stops9h 55m
Southwest
Deal found 5/5![Southwest logo]()
$236
This United Airlines deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/212:55 pm
ORD
- COU
Nonstop1h 35m
United Airlines
Fri 10/25:00 am
COU
- ORD
Nonstop1h 41m
United Airlines
Deal found 5/3![United Airlines logo]()
$239
This Delta deal was found by Cheapflights users on 5/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/1211:30 am
ORD
- STL
1 stop5h 53m
Delta
Tue 6/161:59 pm
STL
- ORD
1 stop6h 32m
Delta
Deal found 5/2![Delta logo]()
$257
This American Airlines deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/225:34 pm
ORD
- COU
1 stop5h 12m
American Airlines
Tue 5/267:16 am
COU
- ORD
1 stop7h 04m
American Airlines
Deal found 5/1![American Airlines logo]()
$258
This United Airlines deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/228:08 pm
ORD
- COU
Nonstop1h 51m
United Airlines
Tue 5/263:25 pm
COU
- ORD
Nonstop1h 40m
United Airlines
Deal found 5/1![United Airlines logo]()
$239
This American Airlines deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/36:00 am
ORD
- COU
1 stop5h 14m
American Airlines
Wed 6/105:19 pm
COU
- ORD
1 stop7h 20m
American Airlines
Deal found 5/4![American Airlines logo]()
$258
This Southwest deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/239:15 am
MDW
- STL
Nonstop1h 15m
Southwest
Mon 5/257:20 am
STL
- MDW
Nonstop1h 10m
Southwest
Deal found 5/1![Southwest logo]()
$261
This United Airlines deal was found by Cheapflights users on 5/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/308:08 pm
ORD
- COU
Nonstop1h 51m
United Airlines
Sat 6/610:48 am
COU
- ORD
Nonstop1h 41m
United Airlines
Deal found 5/2![United Airlines logo]()
$239
This Delta deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/235:10 pm
MDW
- STL
1 stop4h 28m
Delta
Mon 5/251:59 pm
STL
- MDW
1 stop4h 34m
Delta
Deal found 5/1![Delta logo]()
$265
This United Airlines deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/28:40 am
ORD
- COU
Nonstop1h 33m
United Airlines
Tue 6/98:00 am
COU
- ORD
Nonstop1h 40m
United Airlines
Deal found 5/1![United Airlines logo]()
$239
This Delta deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/59:49 am
ORD
- SGF
1 stop4h 48m
Delta
Tue 6/96:57 pm
SGF
- ORD
1 stop5h 02m
Delta
Deal found 5/4![Delta logo]()
$269
This Southwest deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/911:50 am
MDW
- STL
1 stop5h 35m
Southwest
Sat 6/135:20 am
STL
- MDW
2 stops6h 55m
Southwest
Deal found 5/6![Southwest logo]()
$273
This United Airlines deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/38:40 am
ORD
- COU
Nonstop1h 33m
United Airlines
Wed 6/103:25 pm
COU
- ORD
Nonstop1h 40m
United Airlines
Deal found 5/4![United Airlines logo]()
$239
This Delta deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/25:15 pm
MDW
- SGF
1 stop5h 04m
Delta
Tue 6/96:00 am
SGF
- MDW
1 stop6h 05m
Delta
Deal found 5/3![Delta logo]()
$269
This Southwest deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/51:25 pm
DTW
- STL
2 stops8h 35m
Southwest
Sat 6/612:50 pm
STL
- DTW
2 stops9h 55m
Southwest
Deal found 5/3![Southwest logo]()
$275
This Delta deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/301:44 pm
ORD
- STL
2 stops9h 37m
Delta
Mon 6/15:36 pm
STL
- ORD
1 stop3h 44m
Delta
Deal found 5/3![Delta logo]()
$270
This Southwest deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/45:45 pm
DTW
- STL
2 stops6h 00m
Southwest
Fri 6/59:55 am
STL
- DTW
2 stops8h 40m
Southwest
Deal found 5/1![Southwest logo]()
$275
This KAYAK deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/316:45 am
ORD
- MCI
Nonstop1h 50m
American Airlines
Tue 6/25:30 am
MCI
- ORD
Nonstop2h 00m
American Airlines
Deal found 5/1![American Airlines logo]()
$345
This Delta deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/32:00 pm
ORD
- STL
2 stops9h 21m
Delta
Wed 6/106:21 am
STL
- ORD
2 stops6h 43m
Delta
Deal found 5/3![Delta logo]()
$278
This United Airlines deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/304:45 pm
ORD
- STL
Nonstop1h 29m
United Airlines
Sun 5/3111:25 am
STL
- ORD
Nonstop1h 38m
United Airlines
Deal found 5/4![United Airlines logo]()
$279
This American Airlines deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/215:07 am
ORD
- SGF
1 stop5h 47m
American Airlines
Thu 7/237:53 pm
SGF
- ORD
Nonstop1h 52m
American Airlines
Deal found 5/5![American Airlines logo]()
$347
Last-minute flights from Michigan to MissouriDiscover last-minute flight deals from Michigan to Missouri. Data last updated May 6, 2026 and is based on user searches.
Discover last-minute flight deals from Michigan to Missouri. Data last updated May 6, 2026 and is based on user searches.
This Frontier deal was found by Cheapflights users on 5/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/2612:44 pm
DTW
- STL
1 stop12h 13m
Frontier
Wed 5/275:27 pm
STL
- DTW
1 stop6h 12m
Frontier
Deal found 5/2![Frontier logo]()
$160
This Kiwi.com deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/286:50 am
DTW
- STL
1 stop11h 43m
Frontier
Mon 6/15:27 pm
STL
- DTW
1 stop6h 12m
Frontier
Deal found 5/4![Frontier logo]()
$134
This Kiwi.com deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/296:05 pm
DTW
- STL
1 stop15h 50m
Frontier
Fri 6/55:27 pm
STL
- DTW
1 stop6h 12m
Frontier
Deal found 5/1![Frontier logo]()
$132
This Kiwi.com deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/296:05 pm
DTW
- STL
1 stop15h 50m
Frontier
Mon 6/15:27 pm
STL
- DTW
1 stop6h 12m
Frontier
Deal found 5/3![Frontier logo]()
$155
This Kiwi.com deal was found by Cheapflights users on 5/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/16:05 pm
DTW
- STL
1 stop24h 28m
Frontier
Thu 6/46:33 pm
STL
- DTW
1 stop5h 05m
Frontier
Deal found 5/2![Frontier logo]()
$158
This Kiwi.com deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/36:20 am
DTW
- MCI
1 stop12h 09m
Frontier
Mon 6/86:24 pm
MCI
- DTW
1 stop22h 35m
Frontier
Deal found 5/4![Frontier logo]()
$126
This Kiwi.com deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/46:50 am
DTW
- STL
1 stop11h 43m
Frontier
Tue 6/96:31 pm
STL
- DTW
1 stop21h 22m
Frontier
Deal found 5/5![Frontier logo]()
$124
This Kiwi.com deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/41:59 pm
DTW
- STL
1 stop19h 56m
Frontier
Mon 6/85:27 pm
STL
- DTW
1 stop23h 32m
Frontier
Deal found 5/5![Frontier logo]()
$125
This Kiwi.com deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/46:30 am
DTW
- STL
1 stop12h 03m
Multiple Airlines
Fri 6/55:27 pm
STL
- DTW
1 stop6h 12m
Multiple Airlines
Deal found 5/1![Multiple Airlines logo]()
$137
This Kiwi.com deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/112:02 pm
DTW
- MCI
1 stop28h 19m
Frontier
Mon 6/156:16 pm
MCI
- DTW
1 stop17h 51m
Frontier
Deal found 5/5![Frontier logo]()
$158
This Kiwi.com deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/126:10 am
DTW
- MCI
1 stop12h 11m
Frontier
Mon 6/156:16 pm
MCI
- DTW
1 stop17h 51m
Frontier
Deal found 5/5![Frontier logo]()
$155
This Kiwi.com deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/252:02 pm
DTW
- MCI
1 stop28h 19m
Frontier
Mon 6/296:16 pm
MCI
- DTW
2 stops16h 19m
Frontier
Deal found 5/5![Frontier logo]()
$156
One-way flights from Michigan to MissouriSearch for one-way flight options from Michigan to Missouri. Find affordable one-way fares based on user searches. Data last updated May 6, 2026.
Search for one-way flight options from Michigan to Missouri. Find affordable one-way fares based on user searches. Data last updated May 6, 2026.
This Kiwi.com deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/36:20 am
DTW
- MCI
1 stop12h 09m
Frontier
Deal found 5/4![Frontier logo]()
$63
This Kiwi.com deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/26:30 am
DTW
- STL
1 stop12h 00m
Frontier
Deal found 5/5![Frontier logo]()
$64
This Kiwi.com deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/282:02 pm
DTW
- STL
1 stop19h 55m
Frontier
Deal found 5/6![Frontier logo]()
$65
This Kiwi.com deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/21:59 pm
DTW
- MCI
1 stop28h 30m
Frontier
Deal found 5/5![Frontier logo]()
$65
This Southwest deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/28:15 am
MDW
- STL
Nonstop1h 15m
Southwest
Deal found 5/6![Southwest logo]()
$69
This United Airlines deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/1710:40 am
ORD
- STL
Nonstop1h 31m
United Airlines
Deal found 5/4![United Airlines logo]()
$69
This Kiwi.com deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/312:04 pm
MDW
- STL
1 stop29h 29m
Frontier
Deal found 5/5![Frontier logo]()
$70
This Kiwi.com deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/16:20 am
DTW
- MCI
1 stop12h 09m
Frontier
Deal found 5/4![Frontier logo]()
$70
This Kiwi.com deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/306:55 am
ORD
- STL
1 stop10h 35m
Frontier
Deal found 5/6![Frontier logo]()
$70
This Kiwi.com deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/26:00 am
MDW
- STL
1 stop26h 55m
Frontier
Deal found 5/3![Frontier logo]()
$71
This Kiwi.com deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/31:29 pm
ORD
- STL
1 stop19h 23m
Frontier
Deal found 5/4![Frontier logo]()
$73
This Kiwi.com deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/2912:04 pm
MDW
- STL
1 stop20h 51m
Frontier
Deal found 5/5![Frontier logo]()
$75
Find flight deals from Michigan to Missouri
Keep the following information in mind while searching for Michigan to Missouri flight deals. Data was last updated May 6, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $121 (Kiwi.com) |
One-way from | $63 (Kiwi.com) |
Popular in | April |
Cheapest in | August |
Average price | $257 |
Good round-trip deal | $360 or less |
Good one-way deal | $187 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Michigan to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 6, 2026.
Use the filters below to find and compare flights from Michigan to Missouri that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
DetroitSt. Louis
DTW - STL
DTWSTL
Detroit Metropolitan Wayne County
Tue 6/2
12:31 pm-1:10 pm
Nonstop1h 39m
Lambert-St Louis
Tue 6/9
6:30 am-9:04 am
Nonstop1h 34m
$197
DetroitSt. Louis
DTW - STL
DTWSTL
Detroit Metropolitan Wayne County
Thu 6/4
8:15 pm-8:50 pm
Nonstop1h 35m
Lambert-St Louis
Tue 6/9
7:40 pm-10:10 pm
Nonstop1h 30m
$211
DetroitSt. Louis
DTW - STL
DTWSTL
Detroit Metropolitan Wayne County
Wed 5/27
12:40 pm-8:00 pm
2 stops8h 20m
Lambert-St Louis
Tue 6/2
2:30 pm-10:30 pm
2 stops7h 00m
$235
DetroitSt. Louis
DTW - STL
DTWSTL
Detroit Metropolitan Wayne County
Mon 6/1
8:30 pm-10:45 pm
1 stop3h 15m
Lambert-St Louis
Tue 6/2
11:35 am-10:30 pm
2 stops9h 55m
$236
ChicagoColumbia
ORD - COU
ORDCOU
Chicago O'Hare Intl
Sat 5/30
8:45 am-10:18 am
Nonstop1h 33m
Columbia Regional
Mon 6/1
8:00 am-9:40 am
Nonstop1h 40m
$239
ChicagoColumbia
ORD - COU
ORDCOU
Chicago O'Hare Intl
Fri 7/10
10:00 pm-11:33 pm
Nonstop1h 33m
Columbia Regional
Sat 7/11
8:00 am-9:40 am
Nonstop1h 40m
$239
ChicagoColumbia
ORD - COU
ORDCOU
Chicago O'Hare Intl
Wed 9/2
12:55 pm-2:30 pm
Nonstop1h 35m
Columbia Regional
Fri 10/2
5:00 am-6:41 am
Nonstop1h 41m
$239
ChicagoColumbia
ORD - COU
ORDCOU
Chicago O'Hare Intl
Fri 5/22
8:08 pm-9:59 pm
Nonstop1h 51m
Columbia Regional
Tue 5/26
3:25 pm-5:05 pm
Nonstop1h 40m
$239
ChicagoColumbia
ORD - COU
ORDCOU
Chicago O'Hare Intl
Sat 5/30
8:08 pm-9:59 pm
Nonstop1h 51m
Columbia Regional
Sat 6/6
10:48 am-12:29 pm
Nonstop1h 41m
$239
ChicagoColumbia
ORD - COU
ORDCOU
Chicago O'Hare Intl
Tue 6/2
8:40 am-10:13 am
Nonstop1h 33m
Columbia Regional
Tue 6/9
8:00 am-9:40 am
Nonstop1h 40m
$239
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from Michigan to Missouri
Have a flexible travel schedule? Discover the best time to fly to Missouri from Michigan with our price prediction graph.
DTW-STL
ORD-COU
MDW-SGF
MDW-STL
ORD-STL
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Michigan to Missouri
USMI-USMO
DTW-STL
ORD-COU
MDW-SGF
MDW-STL
How far ahead should I book a flight from Michigan to Missouri?
Booking 69 days in advance of your planned departure date is, on average, the best time to get cheap flights from Michigan to Missouri. The general trend is that the closer you book to the departure date, the more expensive your flight will be.
What is the cheapest month to book a flight from Michigan to Missouri?
Currently, June is the cheapest month in which you can book a flight from Michigan to Missouri (average of $26). Flying from Michigan to Missouri in January is currently the most expensive (average of $145). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from MI to MO?
Find hourly flight availability from Michigan to Missouri. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated May 6, 2026.
It’s typically best to fly out from Michigan to Missouri at noon. Doing so could potentially save you 23% on the flight price compared to flying in the afternoon, which is usually more expensive.
What is the cheapest day to fly from Michigan to Missouri?
Use this chart to determine the cheapest time to fly round-trip from Michigan to Missouri. Price data was last updated on May 2, 2026.
Travelers seeking maximum savings on their Michigan to Missouri flight should consider departing on Sunday at noon when fares are most often at their lowest. Monday evenings flights should be avoided if possible as fares are typically the most expensive at this time.
How much does it cost to fly round-trip from Michigan to Missouri?
Reviews of airlines servicing Missouri
Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated May 6, 2026.
Peruse reviews from past customers who have flown with Southwest,Delta, andUnited Airlines from Michigan to Missouri to help guide your decision. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Food
7.0
Overall
7.9
Entertainment
7.5
Comfort
8.0
Boarding
8.1
Crew
8.6
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Food
7.0
Overall
7.9
Entertainment
7.5
Comfort
8.0
Boarding
8.1
Crew
8.6
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Food
7.0
Overall
7.9
Entertainment
7.5
Comfort
8.0
Boarding
8.1
Crew
8.6
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Food
7.0
Overall
7.9
Entertainment
7.5
Comfort
8.0
Boarding
8.1
Crew
8.6
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Food
7.0
Overall
7.9
Entertainment
7.5
Comfort
8.0
Boarding
8.1
Crew
8.6
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Food
7.0
Overall
7.9
Entertainment
7.5
Comfort
8.0
Boarding
8.1
Crew
8.6
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Related info for your journey
Find useful and relevant information for your journey from Michigan to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
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Alternative routes for Michigan to Missouri
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Missouri by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Michigan to Missouri by cabin class
Find flights from Michigan to Missouri, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Michigan and Missouri flights
Browse other Michigan and Missouri flight options. Last updated on May 6, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Find a return flight route from Missouri
Find the right flight back to Michigan after your stay in Missouri
Michigan to Missouri flights
Consider these flights traveling from Michigan to Missouri.
Top 6 airlines flying from Michigan to Missouri
Discover the top 6 airlines that operate flights from Michigan to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 6, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$28 | Average$148 | FlexibilityNo cancel fee | On-time65% | |
| Cheapest$111 | Average$222 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$120 | Average$373 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$149 | Average$393 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$199 | Average$353 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$228 | Average$394 | FlexibilityNo cancel fee | On-time69% |