$49+ Cheap flights from Michigan to Missouri
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/29. Fares are subject to change and may not be available on all flights or dates of travel.
DTW — STL
Mar 25 — Apr 11
1 adult, Economy
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Find cheap flights from Michigan to Missouri with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Michigan to Missouri
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Cheapest flights from Michigan to MissouriExplore the most affordable flight options available from Michigan to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 23, 2026.
Explore the most affordable flight options available from Michigan to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 23, 2026.
This Kiwi.com deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/186:05 am
DTW
- STL
1 stop5h 32m
Multiple Airlines
Mon 3/2312:16 pm
STL
- DTW
1 stop18h 51m
Multiple Airlines
Deal found 2/20![Multiple Airlines logo]()
$147
This Kiwi.com deal was found by Cheapflights users on 2/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/169:02 am
DTW
- STL
1 stop5h 32m
Frontier
Mon 3/2312:16 pm
STL
- DTW
1 stop18h 51m
Frontier
Deal found 2/21![Frontier logo]()
$151
This Kiwi.com deal was found by Cheapflights users on 2/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/85:17 pm
DTW
- STL
1 stop21h 02m
Frontier
Wed 3/1111:32 am
STL
- DTW
1 stop19h 35m
Frontier
Deal found 2/21![Frontier logo]()
$154
This Kiwi.com deal was found by Cheapflights users on 2/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/18:49 pm
DTW
- STL
1 stop11h 01m
Frontier
Wed 5/68:13 pm
STL
- DTW
1 stop19h 01m
Frontier
Deal found 2/22![Frontier logo]()
$155
This Kiwi.com deal was found by Cheapflights users on 2/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/217:04 pm
DTW
- STL
1 stop12h 46m
Frontier
Thu 4/2311:25 am
STL
- DTW
1 stop20h 45m
Frontier
Deal found 2/22![Frontier logo]()
$156
This Kiwi.com deal was found by Cheapflights users on 2/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/235:07 pm
DTW
- STL
1 stop18h 25m
Frontier
Wed 3/258:12 pm
STL
- DTW
1 stop13h 47m
Frontier
Deal found 2/21![Frontier logo]()
$159
This Kiwi.com deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/246:05 am
DTW
- STL
1 stop5h 27m
Multiple Airlines
Wed 3/258:12 pm
STL
- DTW
1 stop13h 47m
Multiple Airlines
Deal found 2/20![Multiple Airlines logo]()
$160
This Frontier deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/1311:54 am
DTW
- MCI
1 stop9h 04m
Frontier
Thu 4/1611:53 am
MCI
- DTW
1 stop5h 53m
Frontier
Deal found 2/20![Frontier logo]()
$160
This Kiwi.com deal was found by Cheapflights users on 2/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/306:30 am
DTW
- STL
1 stop5h 00m
Multiple Airlines
Wed 5/68:13 pm
STL
- DTW
1 stop19h 01m
Multiple Airlines
Deal found 2/22![Multiple Airlines logo]()
$164
This Kiwi.com deal was found by Cheapflights users on 2/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/2210:27 pm
DTW
- STL
1 stop12h 22m
Frontier
Tue 3/2411:27 am
STL
- DTW
1 stop19h 40m
Frontier
Deal found 2/22![Frontier logo]()
$166
This Kiwi.com deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/511:54 am
DTW
- STL
1 stop22h 54m
Frontier
Tue 4/711:21 am
STL
- DTW
1 stop19h 41m
Frontier
Deal found 2/19![Frontier logo]()
$168
This Kiwi.com deal was found by Cheapflights users on 2/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/76:05 am
DTW
- STL
1 stop5h 25m
Multiple Airlines
Thu 4/96:29 pm
STL
- DTW
1 stop12h 33m
Multiple Airlines
Deal found 2/23![Multiple Airlines logo]()
$169
Best flights from Michigan to MissouriDiscover carefully curated flight deals from Michigan to Missouri that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated February 23, 2026.
Discover carefully curated flight deals from Michigan to Missouri that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated February 23, 2026.
This United Airlines deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/158:04 pm
ORD
- SGF
Nonstop1h 55m
United Airlines
Sun 3/223:10 pm
SGF
- ORD
Nonstop1h 49m
United Airlines
Deal found 2/20![United Airlines logo]()
$189
This Kiwi.com deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/217:04 pm
DTW
- STL
1 stop12h 46m
Frontier
Fri 4/248:23 pm
STL
- DTW
1 stop14h 22m
Frontier
Deal found 2/19![Frontier logo]()
$197
This Southwest deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/127:00 am
DTW
- STL
Nonstop1h 45m
Southwest
Sat 3/147:40 pm
STL
- DTW
Nonstop1h 30m
Southwest
Deal found 2/19![Southwest logo]()
$215
This American Airlines deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/168:00 am
ORD
- SGF
Nonstop1h 51m
American Airlines
Sat 5/237:53 pm
SGF
- ORD
Nonstop1h 52m
American Airlines
Deal found 2/19![American Airlines logo]()
$222
This KAYAK deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/61:57 pm
ORD
- STL
1 stop6h 45m
Delta
Thu 4/96:59 pm
STL
- ORD
1 stop4h 55m
Delta
Deal found 2/19![Delta logo]()
$244
This Kiwi.com deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/151:40 pm
ORD
- MCI
2 stops18h 14m
Multiple Airlines
Mon 4/2011:13 am
MCI
- ORD
1 stop7h 41m
Multiple Airlines
Deal found 2/19![Multiple Airlines logo]()
$267
This Alaska Airlines deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/297:09 am
DTW
- MCI
1 stop17h 50m
Alaska Airlines
Wed 5/62:58 pm
MCI
- DTW
1 stop13h 46m
Alaska Airlines
Deal found 2/19![Alaska Airlines logo]()
$323
This United Airlines deal was found by Cheapflights users on 2/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/137:58 pm
ORD
- COU
Nonstop1h 35m
United Airlines
Sun 3/158:00 am
COU
- ORD
Nonstop1h 30m
United Airlines
Deal found 2/22![United Airlines logo]()
$194
This Southwest deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/1111:50 am
ORD
- MCI
1 stop9h 00m
Southwest
Mon 4/135:20 am
MCI
- ORD
1 stop7h 55m
Southwest
Deal found 2/19![Southwest logo]()
$229
This American Airlines deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/265:00 pm
ORD
- MCI
1 stop6h 59m
American Airlines
Fri 3/275:00 am
MCI
- ORD
Nonstop1h 41m
American Airlines
Deal found 2/19![American Airlines logo]()
$243
This Expedia deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/123:49 pm
DTW
- STL
1 stop8h 30m
Frontier
Sat 3/148:12 pm
STL
- DTW
1 stop13h 47m
Frontier
Deal found 2/19![Frontier logo]()
$244
This Delta deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/179:35 am
MDW
- MCI
2 stops7h 59m
Delta
Sat 3/216:35 am
MCI
- MDW
1 stop5h 54m
Delta
Deal found 2/19![Delta logo]()
$251
This Southwest deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/257:35 am
MDW
- MCI
Nonstop1h 30m
Southwest
Fri 3/275:30 am
MCI
- MDW
Nonstop1h 25m
Southwest
Deal found 2/19![Southwest logo]()
$233
This United Airlines deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/158:40 am
ORD
- MCI
Nonstop1h 47m
United Airlines
Wed 4/228:00 am
MCI
- ORD
Nonstop1h 42m
United Airlines
Deal found 2/19![United Airlines logo]()
$251
This American Airlines deal was found by Cheapflights users on 2/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/2410:27 am
GRR
- STL
1 stop7h 14m
American Airlines
Tue 4/288:03 pm
STL
- GRR
1 stop12h 21m
American Airlines
Deal found 2/21![American Airlines logo]()
$253
This Delta deal was found by Cheapflights users on 2/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/195:30 am
ORD
- SGF
1 stop5h 38m
Delta
Mon 3/233:56 pm
SGF
- ORD
1 stop5h 14m
Delta
Deal found 2/21![Delta logo]()
$254
This Southwest deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/186:00 am
MDW
- MCI
1 stop4h 55m
Southwest
Wed 3/2511:05 am
MCI
- MDW
1 stop6h 00m
Southwest
Deal found 2/19![Southwest logo]()
$235
This Frontier deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/511:55 am
ORD
- STL
1 stop12h 04m
Frontier
Sun 3/84:51 pm
STL
- ORD
1 stop6h 47m
Frontier
Deal found 2/19![Frontier logo]()
$270
This United Airlines deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/156:00 pm
ORD
- MCI
Nonstop1h 45m
United Airlines
Tue 4/218:00 am
MCI
- ORD
Nonstop1h 42m
United Airlines
Deal found 2/19![United Airlines logo]()
$251
This Delta deal was found by Cheapflights users on 2/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/87:07 am
ORD
- SGF
1 stop7h 30m
Delta
Tue 5/193:22 pm
SGF
- ORD
1 stop5h 04m
Delta
Deal found 2/22![Delta logo]()
$254
This Kiwi.com deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/105:31 pm
DTW
- STL
1 stop7h 27m
Multiple Airlines
Sun 4/1211:33 am
STL
- DTW
1 stop19h 29m
Multiple Airlines
Deal found 2/19![Multiple Airlines logo]()
$309
This Southwest deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/97:50 am
MDW
- MCI
Nonstop1h 30m
Southwest
Mon 4/135:30 am
MCI
- MDW
Nonstop1h 25m
Southwest
Deal found 2/19![Southwest logo]()
$237
This United Airlines deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/199:33 pm
ORD
- STL
Nonstop1h 26m
United Airlines
Thu 3/265:00 am
STL
- ORD
Nonstop1h 30m
United Airlines
Deal found 2/19![United Airlines logo]()
$251
This American Airlines deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/198:40 am
ORD
- STL
Nonstop1h 23m
American Airlines
Thu 3/266:00 am
STL
- ORD
Nonstop1h 28m
American Airlines
Deal found 2/19![American Airlines logo]()
$278
This Alaska Airlines deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/174:55 pm
DTW
- MCI
1 stop21h 34m
Alaska Airlines
Tue 4/212:23 pm
MCI
- DTW
1 stop14h 21m
Alaska Airlines
Deal found 2/19![Alaska Airlines logo]()
$343
This Delta deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/91:44 pm
ORD
- MCI
2 stops9h 29m
Delta
Sat 5/166:19 am
MCI
- ORD
2 stops6h 37m
Delta
Deal found 2/19![Delta logo]()
$261
This Southwest deal was found by Cheapflights users on 2/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/175:40 pm
MDW
- STL
Nonstop1h 15m
Southwest
Mon 4/208:25 am
STL
- MDW
2 stops6h 30m
Southwest
Deal found 2/22![Southwest logo]()
$241
This Kiwi.com deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/192:41 pm
MDW
- STL
1 stop22h 53m
Frontier
Thu 3/2611:21 am
STL
- MDW
1 stop8h 26m
Frontier
Deal found 2/19![Frontier logo]()
$298
This Alaska Airlines deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/134:55 pm
DTW
- MCI
1 stop21h 34m
Alaska Airlines
Tue 4/212:23 pm
MCI
- DTW
1 stop14h 21m
Alaska Airlines
Deal found 2/19![Alaska Airlines logo]()
$343
This American Airlines deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/63:43 pm
ORD
- SGF
Nonstop1h 47m
American Airlines
Tue 4/75:27 pm
SGF
- ORD
1 stop6h 27m
American Airlines
Deal found 2/19![American Airlines logo]()
$287
Last-minute flights from Michigan to MissouriDiscover last-minute flight deals from Michigan to Missouri. Data last updated February 23, 2026 and is based on user searches.
Discover last-minute flight deals from Michigan to Missouri. Data last updated February 23, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 2/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/85:17 pm
DTW
- STL
1 stop21h 02m
Frontier
Wed 3/1111:32 am
STL
- DTW
1 stop19h 35m
Frontier
Deal found 2/21![Frontier logo]()
$154
This Kiwi.com deal was found by Cheapflights users on 2/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/85:17 pm
DTW
- STL
1 stop21h 02m
Multiple Airlines
Wed 3/1111:32 am
STL
- DTW
2 stops11h 27m
Multiple Airlines
Deal found 2/22![Multiple Airlines logo]()
$179
This United Airlines deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/158:04 pm
ORD
- SGF
Nonstop1h 55m
United Airlines
Sun 3/223:10 pm
SGF
- ORD
Nonstop1h 49m
United Airlines
Deal found 2/20![United Airlines logo]()
$189
This Kiwi.com deal was found by Cheapflights users on 2/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/169:02 am
DTW
- STL
1 stop5h 32m
Frontier
Mon 3/2312:16 pm
STL
- DTW
1 stop18h 51m
Frontier
Deal found 2/21![Frontier logo]()
$151
This Kiwi.com deal was found by Cheapflights users on 2/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/169:02 am
DTW
- MCI
1 stop9h 23m
Frontier
Wed 3/1811:45 am
MCI
- DTW
1 stop19h 22m
Frontier
Deal found 2/22![Frontier logo]()
$182
This Kiwi.com deal was found by Cheapflights users on 2/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/169:53 pm
DTW
- STL
2 stops37h 44m
Multiple Airlines
Mon 3/2312:16 pm
STL
- DTW
1 stop18h 51m
Multiple Airlines
Deal found 2/21![Multiple Airlines logo]()
$184
This Kiwi.com deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/186:05 am
DTW
- STL
1 stop5h 32m
Multiple Airlines
Mon 3/2312:16 pm
STL
- DTW
1 stop18h 51m
Multiple Airlines
Deal found 2/20![Multiple Airlines logo]()
$147
This American Airlines deal was found by Cheapflights users on 2/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/208:05 am
ORD
- COU
Nonstop1h 28m
American Airlines
Mon 3/236:30 pm
COU
- ORD
Nonstop1h 35m
American Airlines
Deal found 2/22![American Airlines logo]()
$179
This Kiwi.com deal was found by Cheapflights users on 2/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/2210:27 pm
DTW
- STL
1 stop12h 22m
Frontier
Tue 3/2411:27 am
STL
- DTW
1 stop19h 40m
Frontier
Deal found 2/22![Frontier logo]()
$166
This Kiwi.com deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/2210:27 pm
DTW
- STL
1 stop12h 22m
Frontier
Thu 3/2611:21 am
STL
- DTW
1 stop19h 46m
Frontier
Deal found 2/20![Frontier logo]()
$173
This Kiwi.com deal was found by Cheapflights users on 2/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/235:07 pm
DTW
- STL
1 stop18h 25m
Frontier
Wed 3/258:12 pm
STL
- DTW
1 stop13h 47m
Frontier
Deal found 2/21![Frontier logo]()
$159
This Kiwi.com deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/246:05 am
DTW
- STL
1 stop5h 27m
Multiple Airlines
Wed 3/258:12 pm
STL
- DTW
1 stop13h 47m
Multiple Airlines
Deal found 2/20![Multiple Airlines logo]()
$160
One-way flights from Michigan to MissouriSearch for one-way flight options from Michigan to Missouri. Find affordable one-way fares based on user searches. Data last updated February 23, 2026.
Search for one-way flight options from Michigan to Missouri. Find affordable one-way fares based on user searches. Data last updated February 23, 2026.
This Southwest deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/1910:15 am
MDW
- STL
Nonstop1h 15m
Southwest
Deal found 2/20![Southwest logo]()
$49
This United Airlines deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/317:40 pm
ORD
- STL
Nonstop1h 28m
United Airlines
Deal found 2/20![United Airlines logo]()
$49
This United Airlines deal was found by Cheapflights users on 2/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/288:15 pm
ORD
- MCI
Nonstop1h 44m
United Airlines
Deal found 2/22![United Airlines logo]()
$56
This Southwest deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/187:50 am
MDW
- STL
Nonstop1h 15m
Southwest
Deal found 2/20![Southwest logo]()
$59
This United Airlines deal was found by Cheapflights users on 2/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/57:00 am
ORD
- STL
Nonstop1h 25m
United Airlines
Deal found 2/23![United Airlines logo]()
$59
This Southwest deal was found by Cheapflights users on 2/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/811:35 am
MDW
- STL
2 stops6h 20m
Southwest
Deal found 2/21![Southwest logo]()
$64
This Southwest deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/202:40 pm
ORD
- STL
1 stop7h 20m
Southwest
Deal found 2/20![Southwest logo]()
$64
This United Airlines deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/1810:56 am
ORD
- STL
Nonstop1h 31m
United Airlines
Deal found 2/20![United Airlines logo]()
$66
This Kiwi.com deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/287:04 pm
DTW
- STL
1 stop12h 46m
Frontier
Deal found 2/19![Frontier logo]()
$69
This Southwest deal was found by Cheapflights users on 2/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/113:05 pm
MDW
- STL
1 stop5h 15m
Southwest
Deal found 2/22![Southwest logo]()
$69
This Southwest deal was found by Cheapflights users on 2/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/22:05 pm
ORD
- STL
1 stop6h 15m
Southwest
Deal found 2/22![Southwest logo]()
$69
This Kiwi.com deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/2112:33 pm
DTW
- STL
1 stop19h 17m
Frontier
Deal found 2/20![Frontier logo]()
$70
Find flight deals from Michigan to Missouri
Keep the following information in mind while searching for Michigan to Missouri flight deals. Data was last updated February 23, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $147 (Kiwi.com) |
One-way from | $49 (Southwest) |
Popular in | February |
Cheapest in | August |
Average price | $439 |
Good round-trip deal | $319 or less |
Good one-way deal | $169 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Michigan to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 23, 2026.
Use the filters below to find and compare flights from Michigan to Missouri that are best for you.
Fly from
Michigan
Fly to
Missouri
Route
Depart
Return
Price
ChicagoSpringfield
ORD - SGF
ORDSGF
Chicago O'Hare Intl
Sun 3/15
8:04 pm-9:59 pm
Nonstop1h 55m
Springfield-Branson
Sun 3/22
3:10 pm-4:59 pm
Nonstop1h 49m
$189
ChicagoColumbia
ORD - COU
ORDCOU
Chicago O'Hare Intl
Fri 3/13
7:58 pm-9:33 pm
Nonstop1h 35m
Columbia Regional
Sun 3/15
8:00 am-9:30 am
Nonstop1h 30m
$194
DetroitSt. Louis
DTW - STL
DTWSTL
Detroit Metropolitan Wayne County
Tue 4/21
7:04 pm-6:50 am
1 stop12h 46m
Lambert-St Louis
Fri 4/24
8:23 pm-11:45 am
1 stop14h 22m
$197
DetroitSt. Louis
DTW - STL
DTWSTL
Detroit Metropolitan Wayne County
Thu 3/12
7:00 am-7:45 am
Nonstop1h 45m
Lambert-St Louis
Sat 3/14
7:40 pm-10:10 pm
Nonstop1h 30m
$215
ChicagoSpringfield
ORD - SGF
ORDSGF
Chicago O'Hare Intl
Sat 5/16
8:00 am-9:51 am
Nonstop1h 51m
Springfield-Branson
Sat 5/23
7:53 pm-9:45 pm
Nonstop1h 52m
$222
ChicagoKansas City
ORD - MCI
ORDMCI
Chicago O'Hare Intl
Sat 4/11
11:50 am-8:50 pm
1 stop9h 00m
Kansas City
Mon 4/13
5:20 am-1:15 pm
1 stop7h 55m
$229
ChicagoKansas City
MDW - MCI
MDWMCI
Chicago Midway
Wed 3/25
7:35 am-9:05 am
Nonstop1h 30m
Kansas City
Fri 3/27
5:30 am-6:55 am
Nonstop1h 25m
$233
ChicagoKansas City
MDW - MCI
MDWMCI
Chicago Midway
Wed 3/18
6:00 am-10:55 am
1 stop4h 55m
Kansas City
Wed 3/25
11:05 am-5:05 pm
1 stop6h 00m
$235
ChicagoKansas City
MDW - MCI
MDWMCI
Chicago Midway
Thu 4/9
7:50 am-9:20 am
Nonstop1h 30m
Kansas City
Mon 4/13
5:30 am-6:55 am
Nonstop1h 25m
$237
ChicagoSt. Louis
MDW - STL
MDWSTL
Chicago Midway
Fri 4/17
5:40 pm-6:55 pm
Nonstop1h 15m
Lambert-St Louis
Mon 4/20
8:25 am-2:55 pm
2 stops6h 30m
$241
Showing 1-10 of 60 results
Best time to book a flight from Michigan to Missouri
Have a flexible travel schedule? Discover the best time to fly to Missouri from Michigan with our price prediction graph.
ORD-SGF
DTW-STL
ORD-STL
ORD-MCI
DTW-MCI
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Michigan to Missouri
USMI-USMO
ORD-SGF
DTW-STL
ORD-STL
ORD-MCI
What is the cheapest month to book a flight from Michigan to Missouri?
Currently, August is the cheapest month in which you can book a flight from Michigan to Missouri (average of $40). Flying from Michigan to Missouri in January is currently the most expensive (average of $253). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from MI to MO?
Find hourly flight availability from Michigan to Missouri. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated February 23, 2026.
It’s typically best to fly out from Michigan to Missouri at noon. Doing so could potentially save you 20% on the flight price compared to flying in the afternoon, which is usually more expensive.
What is the cheapest day to fly from Michigan to Missouri?
Use this chart to determine the cheapest time to fly round-trip from Michigan to Missouri. Price data was last updated on February 21, 2026.
Travelers seeking maximum savings on their Michigan to Missouri flight should consider departing on Sunday at noon when fares are most often at their lowest. Monday afternoons flights should be avoided if possible as fares are typically the most expensive at this time.
Weekly flight availability from Michigan to Missouri
Explore weekly flight availability from Michigan to Missouri. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated February 23, 2026.
The most flights from USMI to USMO are scheduled on a Monday (13 on average). You will have fewer flight options on Tuesday, which is when the least amount of flights are scheduled (10 on average).
Reviews of airlines servicing Missouri
Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated February 23, 2026.
Peruse reviews from past customers who have flown with Southwest, Delta, and United Airlines from Michigan to Missouri to help guide your decision. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Comfort
8.0
Overall
8.0
Entertainment
7.5
Food
7.0
Boarding
8.1
Crew
8.6
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Comfort
8.0
Overall
8.0
Entertainment
7.5
Food
7.0
Boarding
8.1
Crew
8.6
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Comfort
8.0
Overall
8.0
Entertainment
7.5
Food
7.0
Boarding
8.1
Crew
8.6
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Comfort
8.0
Overall
8.0
Entertainment
7.5
Food
7.0
Boarding
8.1
Crew
8.6
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Comfort
8.0
Overall
8.0
Entertainment
7.5
Food
7.0
Boarding
8.1
Crew
8.6
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Comfort
8.0
Overall
8.0
Entertainment
7.5
Food
7.0
Boarding
8.1
Crew
8.6
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Related info for your journey
Find useful and relevant information for your journey from Michigan to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Michigan to Missouri
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Missouri by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Michigan to Missouri by cabin class
Find flights from Michigan to Missouri, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Michigan and Missouri flights
Browse other Michigan and Missouri flight options. Last updated on February 23, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Find a return flight route from Missouri
Find the right flight back to Michigan after your stay in Missouri
Michigan to Missouri flights
Consider these flights traveling from Michigan to Missouri.
Top 6 airlines flying from Michigan to Missouri
Discover the top 6 airlines that operate flights from Michigan to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 23, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$28 | Average$138 | FlexibilityNo cancel fee | On-time65% | |
| Cheapest$111 | Average$228 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$121 | Average$393 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$121 | Average$358 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$199 | Average$358 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$228 | Average$399 | FlexibilityNo cancel fee | On-time69% |