$43+ Cheap flights from Michigan to Missouri
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/25. Fares are subject to change and may not be available on all flights or dates of travel.
DTW — STL
Mar 20 — Mar 271
1 adult, Economy
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Find cheap flights from Michigan to Missouri with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Michigan to Missouri
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Cheapest flights from Michigan to MissouriExplore the most affordable flight options available from Michigan to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 18, 2026.
Explore the most affordable flight options available from Michigan to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 18, 2026.
This United Airlines deal was found by Cheapflights users on 2/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/307:05 am
ORD
- STL
Nonstop1h 36m
United Airlines
Sat 5/301:13 pm
STL
- ORD
Nonstop1h 30m
United Airlines
Deal found 2/15![United Airlines logo]()
$85
This American Airlines deal was found by Cheapflights users on 2/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/96:59 am
ORD
- STL
Nonstop1h 25m
American Airlines
Sat 4/117:05 am
STL
- ORD
Nonstop1h 31m
American Airlines
Deal found 2/15![American Airlines logo]()
$91
This American Airlines deal was found by Cheapflights users on 2/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/287:46 pm
ORD
- STL
Nonstop1h 25m
American Airlines
Tue 3/318:00 am
STL
- ORD
Nonstop1h 31m
American Airlines
Deal found 2/15![American Airlines logo]()
$94
This Southwest deal was found by Cheapflights users on 2/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/179:05 pm
MDW
- STL
Nonstop1h 15m
Southwest
Tue 3/2410:30 am
STL
- MDW
Nonstop1h 10m
Southwest
Deal found 2/17![Southwest logo]()
$97
This American Airlines deal was found by Cheapflights users on 2/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/2710:22 pm
ORD
- STL
Nonstop1h 13m
American Airlines
Sun 3/296:00 am
STL
- ORD
Nonstop1h 28m
American Airlines
Deal found 2/16![American Airlines logo]()
$97
This American Airlines deal was found by Cheapflights users on 2/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/710:34 pm
ORD
- STL
Nonstop1h 17m
American Airlines
Sun 8/97:23 am
STL
- ORD
Nonstop1h 25m
American Airlines
Deal found 2/15![American Airlines logo]()
$111
This American Airlines deal was found by Cheapflights users on 2/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/46:45 am
ORD
- STL
Nonstop1h 20m
American Airlines
Sun 9/67:23 am
STL
- ORD
Nonstop1h 25m
American Airlines
Deal found 2/15![American Airlines logo]()
$112
This Southwest deal was found by Cheapflights users on 2/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/174:15 pm
ORD
- STL
1 stop5h 10m
Southwest
Tue 3/247:30 am
STL
- ORD
1 stop5h 20m
Southwest
Deal found 2/15![Southwest logo]()
$117
This Kiwi.com deal was found by Cheapflights users on 2/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/66:30 pm
ORD
- STL
1 stop15h 19m
Frontier
Sat 3/78:12 pm
STL
- ORD
1 stop12h 31m
Frontier
Deal found 2/15![Frontier logo]()
$128
This Southwest deal was found by Cheapflights users on 2/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/169:30 pm
MDW
- STL
Nonstop1h 15m
Southwest
Sat 4/182:05 pm
STL
- MDW
Nonstop1h 10m
Southwest
Deal found 2/15![Southwest logo]()
$131
This American Airlines deal was found by Cheapflights users on 2/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/127:05 am
ORD
- STL
Nonstop1h 26m
American Airlines
Sun 7/197:15 am
STL
- ORD
Nonstop1h 30m
American Airlines
Deal found 2/14![American Airlines logo]()
$131
This Southwest deal was found by Cheapflights users on 2/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/1110:30 am
MDW
- STL
Nonstop1h 10m
Southwest
Sat 3/285:35 am
STL
- MDW
Nonstop1h 10m
Southwest
Deal found 2/16![Southwest logo]()
$134
Best flights from Michigan to MissouriDiscover carefully curated flight deals from Michigan to Missouri that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated February 18, 2026.
Discover carefully curated flight deals from Michigan to Missouri that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated February 18, 2026.
This American Airlines deal was found by Cheapflights users on 2/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/266:59 am
ORD
- STL
Nonstop1h 25m
American Airlines
Thu 4/305:51 am
STL
- ORD
Nonstop1h 30m
American Airlines
Deal found 2/15![American Airlines logo]()
$91
This United Airlines deal was found by Cheapflights users on 2/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/203:03 pm
ORD
- STL
Nonstop1h 36m
United Airlines
Sat 5/301:13 pm
STL
- ORD
Nonstop1h 30m
United Airlines
Deal found 2/14![United Airlines logo]()
$91
This Southwest deal was found by Cheapflights users on 2/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/179:05 pm
MDW
- STL
Nonstop1h 15m
Southwest
Tue 3/2410:30 am
STL
- MDW
Nonstop1h 10m
Southwest
Deal found 2/17![Southwest logo]()
$97
This Delta deal was found by Cheapflights users on 2/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/166:00 am
MDW
- STL
1 stop4h 34m
Delta
Sat 4/1812:23 pm
STL
- MDW
1 stop6h 13m
Delta
Deal found 2/15![Delta logo]()
$174
This American Airlines deal was found by Cheapflights users on 2/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/3110:30 pm
ORD
- STL
Nonstop1h 14m
American Airlines
Thu 4/26:00 am
STL
- ORD
Nonstop1h 28m
American Airlines
Deal found 2/14![American Airlines logo]()
$91
This Southwest deal was found by Cheapflights users on 2/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/104:45 pm
MDW
- STL
Nonstop1h 15m
Southwest
Tue 3/108:50 pm
STL
- MDW
Nonstop1h 05m
Southwest
Deal found 2/17![Southwest logo]()
$97
This American Airlines deal was found by Cheapflights users on 2/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/16:59 am
ORD
- STL
Nonstop1h 25m
American Airlines
Mon 5/45:51 am
STL
- ORD
Nonstop1h 30m
American Airlines
Deal found 2/14![American Airlines logo]()
$91
This Kiwi.com deal was found by Cheapflights users on 2/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/48:59 pm
DTW
- STL
2 stops34h 51m
Multiple Airlines
Sat 5/98:12 pm
STL
- DTW
1 stop13h 46m
Multiple Airlines
Deal found 2/14![Multiple Airlines logo]()
$208
This American Airlines deal was found by Cheapflights users on 2/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/106:59 am
ORD
- STL
Nonstop1h 25m
American Airlines
Sun 4/127:05 am
STL
- ORD
Nonstop1h 31m
American Airlines
Deal found 2/15![American Airlines logo]()
$91
This Expedia deal was found by Cheapflights users on 2/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/2010:27 pm
DTW
- STL
1 stop12h 22m
Frontier
Sun 3/229:05 pm
STL
- DTW
1 stop27h 36m
Frontier
Deal found 2/17![Frontier logo]()
$230
This American Airlines deal was found by Cheapflights users on 2/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/1810:30 pm
ORD
- STL
Nonstop1h 16m
American Airlines
Mon 4/207:05 am
STL
- ORD
Nonstop1h 31m
American Airlines
Deal found 2/15![American Airlines logo]()
$91
This United Airlines deal was found by Cheapflights users on 2/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/79:33 pm
ORD
- STL
Nonstop1h 26m
United Airlines
Mon 3/97:00 pm
STL
- ORD
Nonstop1h 35m
United Airlines
Deal found 2/14![United Airlines logo]()
$128
This Southwest deal was found by Cheapflights users on 2/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/174:15 pm
ORD
- STL
1 stop5h 10m
Southwest
Tue 3/247:30 am
STL
- ORD
1 stop5h 20m
Southwest
Deal found 2/15![Southwest logo]()
$117
This American Airlines deal was found by Cheapflights users on 2/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/277:20 am
ORD
- STL
Nonstop1h 31m
American Airlines
Sun 3/296:00 am
STL
- ORD
Nonstop1h 28m
American Airlines
Deal found 2/16![American Airlines logo]()
$98
This United Airlines deal was found by Cheapflights users on 2/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/67:40 pm
ORD
- STL
Nonstop1h 28m
United Airlines
Wed 4/89:10 am
STL
- ORD
Nonstop1h 30m
United Airlines
Deal found 2/17![United Airlines logo]()
$134
This United Airlines deal was found by Cheapflights users on 2/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/112:54 pm
ORD
- STL
Nonstop1h 29m
United Airlines
Sat 3/2810:00 am
STL
- ORD
Nonstop1h 33m
United Airlines
Deal found 2/16![United Airlines logo]()
$134
This Mytrip deal was found by Cheapflights users on 2/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/165:34 pm
DTW
- MCI
3 stops31h 19m
Spirit Airlines
Mon 3/2312:24 pm
MCI
- DTW
2 stops21h 48m
Spirit Airlines
Deal found 2/15![Spirit Airlines logo]()
$339
This Delta deal was found by Cheapflights users on 2/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/205:14 pm
MDW
- STL
1 stop6h 45m
Delta
Sat 5/306:20 am
STL
- MDW
1 stop6h 59m
Delta
Deal found 2/14![Delta logo]()
$174
This Southwest deal was found by Cheapflights users on 2/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/165:40 pm
MDW
- STL
Nonstop1h 15m
Southwest
Tue 3/173:10 pm
STL
- MDW
1 stop4h 45m
Southwest
Deal found 2/17![Southwest logo]()
$144
This United Airlines deal was found by Cheapflights users on 2/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/101:18 pm
ORD
- STL
Nonstop1h 31m
United Airlines
Tue 3/107:00 pm
STL
- ORD
Nonstop1h 35m
United Airlines
Deal found 2/17![United Airlines logo]()
$147
This Southwest deal was found by Cheapflights users on 2/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/135:55 pm
MDW
- STL
1 stop5h 20m
Southwest
Tue 4/144:25 pm
STL
- MDW
1 stop6h 40m
Southwest
Deal found 2/14![Southwest logo]()
$154
This Delta deal was found by Cheapflights users on 2/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/218:10 am
ORD
- SGF
1 stop6h 25m
Delta
Tue 5/263:22 pm
SGF
- ORD
1 stop7h 06m
Delta
Deal found 2/15![Delta logo]()
$209
This Kiwi.com deal was found by Cheapflights users on 2/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/1310:27 pm
DTW
- STL
1 stop12h 22m
Frontier
Sat 3/148:12 pm
STL
- DTW
1 stop13h 47m
Frontier
Deal found 2/17![Frontier logo]()
$237
This Southwest deal was found by Cheapflights users on 2/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/208:15 am
MDW
- STL
Nonstop1h 15m
Southwest
Sat 5/302:05 pm
STL
- MDW
Nonstop1h 10m
Southwest
Deal found 2/14![Southwest logo]()
$162
This Expedia deal was found by Cheapflights users on 2/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/2912:47 pm
DTW
- MCI
1 stop12h 10m
Multiple Airlines
Fri 5/12:15 pm
MCI
- DTW
1 stop6h 26m
Multiple Airlines
Deal found 2/17![Multiple Airlines logo]()
$239
This Delta deal was found by Cheapflights users on 2/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/812:15 pm
ORD
- SGF
2 stops9h 28m
Delta
Mon 4/136:55 pm
SGF
- ORD
1 stop5h 04m
Delta
Deal found 2/14![Delta logo]()
$214
This United Airlines deal was found by Cheapflights users on 2/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/137:58 pm
ORD
- COU
Nonstop1h 35m
United Airlines
Sun 3/158:00 am
COU
- ORD
Nonstop1h 30m
United Airlines
Deal found 2/16![United Airlines logo]()
$179
This Kiwi.com deal was found by Cheapflights users on 2/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/1711:54 am
DTW
- STL
1 stop8h 27m
Frontier
Sun 4/194:55 pm
STL
- DTW
2 stops15h 15m
Frontier
Deal found 2/17![Frontier logo]()
$258
This Delta deal was found by Cheapflights users on 2/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/207:00 am
ORD
- SGF
2 stops7h 35m
Delta
Sat 5/304:00 pm
SGF
- ORD
1 stop5h 49m
Delta
Deal found 2/14![Delta logo]()
$214
This American Airlines deal was found by Cheapflights users on 2/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/26:50 pm
ORD
- COU
Nonstop1h 29m
American Airlines
Sun 4/56:00 am
COU
- ORD
Nonstop1h 36m
American Airlines
Deal found 2/15![American Airlines logo]()
$179
Last-minute flights from Michigan to MissouriDiscover last-minute flight deals from Michigan to Missouri. Data last updated February 18, 2026 and is based on user searches.
Discover last-minute flight deals from Michigan to Missouri. Data last updated February 18, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 2/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/66:30 pm
ORD
- STL
1 stop15h 19m
Frontier
Sat 3/78:12 pm
STL
- ORD
1 stop12h 31m
Frontier
Deal found 2/15![Frontier logo]()
$128
This Kiwi.com deal was found by Cheapflights users on 2/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/85:17 pm
DTW
- STL
1 stop21h 02m
Frontier
Wed 3/1111:32 am
STL
- DTW
1 stop19h 35m
Frontier
Deal found 2/16![Frontier logo]()
$154
This United Airlines deal was found by Cheapflights users on 2/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/101:18 pm
ORD
- STL
Nonstop1h 31m
United Airlines
Tue 3/107:00 pm
STL
- ORD
Nonstop1h 35m
United Airlines
Deal found 2/17![United Airlines logo]()
$147
This Southwest deal was found by Cheapflights users on 2/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/1110:30 am
MDW
- STL
Nonstop1h 10m
Southwest
Sat 3/285:35 am
STL
- MDW
Nonstop1h 10m
Southwest
Deal found 2/16![Southwest logo]()
$134
This United Airlines deal was found by Cheapflights users on 2/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/112:54 pm
ORD
- STL
Nonstop1h 29m
United Airlines
Sat 3/2810:00 am
STL
- ORD
Nonstop1h 33m
United Airlines
Deal found 2/16![United Airlines logo]()
$134
This American Airlines deal was found by Cheapflights users on 2/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/1310:22 pm
ORD
- STL
Nonstop1h 13m
American Airlines
Sat 3/218:00 am
STL
- ORD
Nonstop1h 31m
American Airlines
Deal found 2/15![American Airlines logo]()
$151
This United Airlines deal was found by Cheapflights users on 2/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/144:35 pm
ORD
- STL
Nonstop1h 25m
United Airlines
Sat 3/2110:00 am
STL
- ORD
Nonstop1h 33m
United Airlines
Deal found 2/14![United Airlines logo]()
$145
This Southwest deal was found by Cheapflights users on 2/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/179:05 pm
MDW
- STL
Nonstop1h 15m
Southwest
Tue 3/2410:30 am
STL
- MDW
Nonstop1h 10m
Southwest
Deal found 2/17![Southwest logo]()
$97
This Southwest deal was found by Cheapflights users on 2/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/174:15 pm
ORD
- STL
1 stop5h 10m
Southwest
Tue 3/247:30 am
STL
- ORD
1 stop5h 20m
Southwest
Deal found 2/15![Southwest logo]()
$117
This American Airlines deal was found by Cheapflights users on 2/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/2710:22 pm
ORD
- STL
Nonstop1h 13m
American Airlines
Sun 3/296:00 am
STL
- ORD
Nonstop1h 28m
American Airlines
Deal found 2/16![American Airlines logo]()
$97
This American Airlines deal was found by Cheapflights users on 2/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/287:46 pm
ORD
- STL
Nonstop1h 25m
American Airlines
Tue 3/318:00 am
STL
- ORD
Nonstop1h 31m
American Airlines
Deal found 2/15![American Airlines logo]()
$94
This American Airlines deal was found by Cheapflights users on 2/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/3110:30 pm
ORD
- STL
Nonstop1h 14m
American Airlines
Thu 4/26:00 am
STL
- ORD
Nonstop1h 28m
American Airlines
Deal found 2/14![American Airlines logo]()
$91
One-way flights from Michigan to MissouriSearch for one-way flight options from Michigan to Missouri. Find affordable one-way fares based on user searches. Data last updated February 18, 2026.
Search for one-way flight options from Michigan to Missouri. Find affordable one-way fares based on user searches. Data last updated February 18, 2026.
This United Airlines deal was found by Cheapflights users on 2/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/254:55 pm
ORD
- STL
Nonstop1h 33m
United Airlines
Deal found 2/15![United Airlines logo]()
$43
This Southwest deal was found by Cheapflights users on 2/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/45:40 pm
MDW
- STL
Nonstop1h 15m
Southwest
Deal found 2/15![Southwest logo]()
$46
This American Airlines deal was found by Cheapflights users on 2/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/187:20 am
ORD
- STL
Nonstop1h 31m
American Airlines
Deal found 2/15![American Airlines logo]()
$46
This American Airlines deal was found by Cheapflights users on 2/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/1810:40 pm
ORD
- STL
Nonstop1h 14m
American Airlines
Deal found 2/15![American Airlines logo]()
$47
This Southwest deal was found by Cheapflights users on 2/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/148:55 pm
MDW
- STL
Nonstop1h 15m
Southwest
Deal found 2/17![Southwest logo]()
$49
This United Airlines deal was found by Cheapflights users on 2/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/257:42 pm
ORD
- STL
Nonstop1h 25m
United Airlines
Deal found 2/17![United Airlines logo]()
$49
This Southwest deal was found by Cheapflights users on 2/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/187:55 am
MDW
- MCI
Nonstop1h 30m
Southwest
Deal found 2/16![Southwest logo]()
$56
This American Airlines deal was found by Cheapflights users on 2/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/156:56 am
ORD
- MCI
Nonstop1h 46m
American Airlines
Deal found 2/14![American Airlines logo]()
$56
This American Airlines deal was found by Cheapflights users on 2/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/206:40 am
ORD
- MCI
Nonstop1h 49m
American Airlines
Deal found 2/15![American Airlines logo]()
$57
This Southwest deal was found by Cheapflights users on 2/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/174:15 pm
ORD
- STL
1 stop5h 10m
Southwest
Deal found 2/15![Southwest logo]()
$59
This Southwest deal was found by Cheapflights users on 2/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/132:40 pm
ORD
- STL
1 stop7h 20m
Southwest
Deal found 2/16![Southwest logo]()
$64
This Southwest deal was found by Cheapflights users on 2/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/256:00 am
MDW
- MCI
1 stop7h 00m
Southwest
Deal found 2/16![Southwest logo]()
$66
Find flight deals from Michigan to Missouri
Keep the following information in mind while searching for Michigan to Missouri flight deals. Data was last updated February 18, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $85 (United Airlines) |
One-way from | $43 (United Airlines) |
Popular in | February |
Cheapest in | August |
Average price | $439 |
Good round-trip deal | $299 or less |
Good one-way deal | $164 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Michigan to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 18, 2026.
Use the filters below to find and compare flights from Michigan to Missouri that are best for you.
Fly from
Michigan
Fly to
Missouri
Route
Depart
Return
Price
ChicagoSt. Louis
ORD - STL
ORDSTL
Chicago O'Hare Intl
Sun 4/26
6:59 am-8:24 am
Nonstop1h 25m
Lambert-St Louis
Thu 4/30
5:51 am-7:21 am
Nonstop1h 30m
$91
ChicagoSt. Louis
ORD - STL
ORDSTL
Chicago O'Hare Intl
Wed 5/20
3:03 pm-4:39 pm
Nonstop1h 36m
Lambert-St Louis
Sat 5/30
1:13 pm-2:43 pm
Nonstop1h 30m
$91
ChicagoSt. Louis
ORD - STL
ORDSTL
Chicago O'Hare Intl
Tue 3/31
10:30 pm-11:44 pm
Nonstop1h 14m
Lambert-St Louis
Thu 4/2
6:00 am-7:28 am
Nonstop1h 28m
$91
ChicagoSt. Louis
ORD - STL
ORDSTL
Chicago O'Hare Intl
Fri 5/1
6:59 am-8:24 am
Nonstop1h 25m
Lambert-St Louis
Mon 5/4
5:51 am-7:21 am
Nonstop1h 30m
$91
ChicagoSt. Louis
ORD - STL
ORDSTL
Chicago O'Hare Intl
Fri 4/10
6:59 am-8:24 am
Nonstop1h 25m
Lambert-St Louis
Sun 4/12
7:05 am-8:36 am
Nonstop1h 31m
$91
ChicagoSt. Louis
ORD - STL
ORDSTL
Chicago O'Hare Intl
Sat 4/18
10:30 pm-11:46 pm
Nonstop1h 16m
Lambert-St Louis
Mon 4/20
7:05 am-8:36 am
Nonstop1h 31m
$91
ChicagoSt. Louis
MDW - STL
MDWSTL
Chicago Midway
Tue 3/17
9:05 pm-10:20 pm
Nonstop1h 15m
Lambert-St Louis
Tue 3/24
10:30 am-11:40 am
Nonstop1h 10m
$97
ChicagoSt. Louis
MDW - STL
MDWSTL
Chicago Midway
Tue 3/10
4:45 pm-6:00 pm
Nonstop1h 15m
Lambert-St Louis
Tue 3/10
8:50 pm-9:55 pm
Nonstop1h 05m
$97
ChicagoSt. Louis
ORD - STL
ORDSTL
Chicago O'Hare Intl
Fri 3/27
7:20 am-8:51 am
Nonstop1h 31m
Lambert-St Louis
Sun 3/29
6:00 am-7:28 am
Nonstop1h 28m
$98
ChicagoSt. Louis
ORD - STL
ORDSTL
Chicago O'Hare Intl
Tue 3/17
4:15 pm-9:25 pm
1 stop5h 10m
Lambert-St Louis
Tue 3/24
7:30 am-12:50 pm
1 stop5h 20m
$117
Showing 1-10 of 60 results
Best time to book a flight from Michigan to Missouri
Have a flexible travel schedule? Discover the best time to fly to Missouri from Michigan with our price prediction graph.
ORD-STL
MDW-STL
DTW-STL
DTW-MCI
ORD-SGF
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Michigan to Missouri
USMI-USMO
ORD-STL
MDW-STL
DTW-STL
DTW-MCI
What is the cheapest month to book a flight from Michigan to Missouri?
Currently, August is the cheapest month in which you can book a flight from Michigan to Missouri (average of $40). Flying from Michigan to Missouri in January is currently the most expensive (average of $253). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from MI to MO?
Find hourly flight availability from Michigan to Missouri. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated February 18, 2026.
It’s typically best to fly out from Michigan to Missouri at noon. Doing so could potentially save you 19% on the flight price compared to flying in the afternoon, which is usually more expensive.
What is the cheapest day to fly from Michigan to Missouri?
Use this chart to determine the cheapest time to fly round-trip from Michigan to Missouri. Price data was last updated on February 7, 2026.
Travelers seeking maximum savings on their Michigan to Missouri flight should consider departing on Sunday at noon when fares are most often at their lowest. Monday afternoons flights should be avoided if possible as fares are typically the most expensive at this time.
Weekly flight availability from Michigan to Missouri
Explore weekly flight availability from Michigan to Missouri. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated February 18, 2026.
The most flights from USMI to USMO are scheduled on a Monday (14 on average). You will have fewer flight options on Saturday, which is when the least amount of flights are scheduled (6 on average).
Reviews of airlines servicing Missouri
Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated February 18, 2026.
Peruse reviews from past customers who have flown with Southwest, Delta, and United Airlines from Michigan to Missouri to help guide your decision. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Comfort
8.0
Overall
8.0
Crew
8.6
Boarding
8.1
Entertainment
7.5
Food
7.0
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Comfort
8.0
Overall
8.0
Crew
8.6
Boarding
8.1
Entertainment
7.5
Food
7.0
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Comfort
8.0
Overall
8.0
Crew
8.6
Boarding
8.1
Entertainment
7.5
Food
7.0
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Comfort
8.0
Overall
8.0
Crew
8.6
Boarding
8.1
Entertainment
7.5
Food
7.0
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Comfort
8.0
Overall
8.0
Crew
8.6
Boarding
8.1
Entertainment
7.5
Food
7.0
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Comfort
8.0
Overall
8.0
Crew
8.6
Boarding
8.1
Entertainment
7.5
Food
7.0
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Related info for your journey
Find useful and relevant information for your journey from Michigan to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Michigan to Missouri
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Missouri by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Michigan to Missouri by cabin class
Find flights from Michigan to Missouri, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Michigan and Missouri flights
Browse other Michigan and Missouri flight options. Last updated on February 18, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Find a return flight route from Missouri
Find the right flight back to Michigan after your stay in Missouri
Michigan to Missouri flights
Consider these flights traveling from Michigan to Missouri.
Top 6 airlines flying from Michigan to Missouri
Discover the top 6 airlines that operate flights from Michigan to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 18, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$28 | Average$138 | FlexibilityNo cancel fee | On-time65% | |
| Cheapest$111 | Average$228 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$121 | Average$353 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$137 | Average$392 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$199 | Average$359 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$228 | Average$405 | FlexibilityNo cancel fee | On-time69% |