$48+ Cheap flights from Michigan to Missouri
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/7. Fares are subject to change and may not be available on all flights or dates of travel.
DTW — STL
Feb 28 — Mar 71
1 adult, Economy
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Michigan to Missouri
Cheapest flights from Michigan to MissouriExplore the most affordable flight options available from Michigan to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 29, 2026.
Explore the most affordable flight options available from Michigan to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 29, 2026.
This Southwest deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/251:50 pm
MDW
- STL
Nonstop1h 10m
Southwest
Wed 3/48:20 am
STL
- MDW
Nonstop1h 10m
Southwest
Deal found 1/27![Southwest logo]()
$97
This United Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/257:40 pm
ORD
- STL
Nonstop1h 25m
United Airlines
Wed 3/47:41 am
STL
- ORD
Nonstop1h 29m
United Airlines
Deal found 1/27![United Airlines logo]()
$97
This Southwest deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/116:00 am
MDW
- STL
1 stop5h 30m
Southwest
Wed 3/186:00 pm
STL
- MDW
1 stop4h 50m
Southwest
Deal found 1/28![Southwest logo]()
$117
This Southwest deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/251:45 pm
ORD
- STL
1 stop5h 00m
Southwest
Wed 3/48:15 am
STL
- ORD
1 stop4h 00m
Southwest
Deal found 1/27![Southwest logo]()
$117
This Southwest deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/241:20 pm
MDW
- STL
2 stops7h 15m
Southwest
Tue 3/310:15 am
STL
- MDW
2 stops6h 30m
Southwest
Deal found 1/26![Southwest logo]()
$127
This Expedia deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/258:30 am
DTW
- STL
1 stop8h 23m
Frontier
Wed 3/48:17 pm
STL
- DTW
1 stop10h 50m
Frontier
Deal found 1/27![Frontier logo]()
$128
This Priceline deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/188:30 am
DTW
- MCI
1 stop8h 14m
Frontier
Wed 2/254:39 pm
MCI
- DTW
1 stop6h 01m
Frontier
Deal found 1/28![Frontier logo]()
$128
This Kiwi.com deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/176:02 pm
ORD
- STL
1 stop12h 49m
Frontier
Fri 2/208:20 pm
STL
- ORD
1 stop26h 19m
Frontier
Deal found 1/26![Frontier logo]()
$133
This Southwest deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/36:10 am
MDW
- STL
Nonstop1h 25m
Southwest
Thu 3/52:15 pm
STL
- MDW
Nonstop1h 05m
Southwest
Deal found 1/27![Southwest logo]()
$134
This United Airlines deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/217:40 pm
ORD
- STL
Nonstop1h 25m
United Airlines
Wed 2/257:41 am
STL
- ORD
Nonstop1h 29m
United Airlines
Deal found 1/28![United Airlines logo]()
$134
This Kiwi.com deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/711:54 am
DTW
- MCI
1 stop9h 01m
Frontier
Sun 3/88:40 pm
MCI
- DTW
1 stop13h 19m
Frontier
Deal found 1/27![Frontier logo]()
$135
This CheapOair deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/258:30 am
DTW
- MCI
1 stop8h 14m
Frontier
Sat 2/2810:00 am
MCI
- DTW
1 stop21h 52m
Frontier
Deal found 1/28![Frontier logo]()
$139
Find flight deals from Michigan to Missouri
Keep the following information in mind while searching for Michigan to Missouri flight deals. Data was last updated January 29, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $97 (Southwest) |
One-way from | $48 (Trip.com) |
Popular in | January |
Cheapest in | August |
Average price | $462 |
Good round-trip deal | $327 or less |
Good one-way deal | $190 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Michigan to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 29, 2026.
Use the filters below to find and compare flights from Michigan to Missouri that are best for you.
Fly from
Michigan
Fly to
Missouri
Route
Depart
Return
Price
ChicagoSt. Louis
MDW - STL
MDWSTL
Chicago Midway
Tue 2/24
6:10 am-7:35 am
Nonstop1h 25m
Lambert-St Louis
Tue 3/3
8:20 am-9:30 am
Nonstop1h 10m
$97
ChicagoSt. Louis
ORD - STL
ORDSTL
Chicago O'Hare Intl
Wed 2/25
8:10 pm-9:40 pm
Nonstop1h 30m
Lambert-St Louis
Wed 3/4
7:41 am-9:10 am
Nonstop1h 29m
$97
ChicagoSt. Louis
MDW - STL
MDWSTL
Chicago Midway
Wed 2/25
1:50 pm-3:00 pm
Nonstop1h 10m
Lambert-St Louis
Wed 3/4
6:50 am-1:55 pm
2 stops7h 05m
$112
ChicagoSt. Louis
MDW - STL
MDWSTL
Chicago Midway
Wed 3/11
6:00 am-11:30 am
1 stop5h 30m
Lambert-St Louis
Wed 3/18
6:00 pm-10:50 pm
1 stop4h 50m
$117
ChicagoSt. Louis
ORD - STL
ORDSTL
Chicago O'Hare Intl
Tue 2/24
2:15 pm-8:35 pm
1 stop6h 20m
Lambert-St Louis
Tue 3/3
6:20 am-1:00 pm
1 stop6h 40m
$117
ChicagoSt. Louis
ORD - STL
ORDSTL
Chicago O'Hare Intl
Wed 2/25
2:15 pm-8:35 pm
1 stop6h 20m
Lambert-St Louis
Wed 3/4
8:15 am-12:15 pm
1 stop4h 00m
$117
ChicagoSt. Louis
ORD - STL
ORDSTL
Chicago O'Hare Intl
Sat 2/21
7:40 pm-9:05 pm
Nonstop1h 25m
Lambert-St Louis
Wed 2/25
7:41 am-9:10 am
Nonstop1h 29m
$134
ChicagoSt. Louis
ORD - STL
ORDSTL
Chicago O'Hare Intl
Tue 4/7
8:15 pm-9:47 pm
Nonstop1h 32m
Lambert-St Louis
Thu 4/9
7:45 am-9:11 am
Nonstop1h 26m
$134
ChicagoSt. Louis
MDW - STL
MDWSTL
Chicago Midway
Tue 3/3
6:10 am-7:35 am
Nonstop1h 25m
Lambert-St Louis
Thu 3/5
2:15 pm-3:20 pm
Nonstop1h 05m
$134
ChicagoSt. Louis
MDW - STL
MDWSTL
Chicago Midway
Tue 4/7
8:55 pm-10:10 pm
Nonstop1h 15m
Lambert-St Louis
Sat 4/11
3:40 pm-9:05 pm
1 stop5h 25m
$144
Showing 1-10 of 60 results
Best time to book a flight from Michigan to Missouri
Have a flexible travel schedule? Discover the best time to fly to Missouri from Michigan with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Michigan to Missouri
What is the cheapest month to book a flight from Michigan to Missouri?
Currently, August is the cheapest month in which you can book a flight from Michigan to Missouri (average of $40). Flying from Michigan to Missouri in January is currently the most expensive (average of $252). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from MI to MO?
Find hourly flight availability from Michigan to Missouri. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated January 29, 2026.
It’s typically best to fly out from Michigan to Missouri at noon. Doing so could potentially save you 20% on the flight price compared to flying in the afternoon, which is usually more expensive.
What is the cheapest day to fly from Michigan to Missouri?
Use this chart to determine the cheapest time to fly round-trip from Michigan to Missouri. Price data was last updated on January 24, 2026.
Travelers seeking maximum savings on their Michigan to Missouri flight should consider departing on Sunday at noon when fares are most often at their lowest. Monday afternoons flights should be avoided if possible as fares are typically the most expensive at this time.
Weekly flight availability from Michigan to Missouri
Explore weekly flight availability from Michigan to Missouri. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated January 29, 2026.
The most flights from USMI to USMO are scheduled on a Monday (13 on average). You will have fewer flight options on Sunday, which is when the least amount of flights are scheduled (10 on average).
Reviews of airlines servicing Missouri
Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated January 29, 2026.
Peruse reviews from past customers who have flown with Southwest, Delta, and United Airlines from Michigan to Missouri to help guide your decision. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Boarding
8.1
Food
7.0
Overall
8.0
Crew
8.6
Entertainment
7.5
Comfort
8.0
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Boarding
8.1
Food
7.0
Overall
8.0
Crew
8.6
Entertainment
7.5
Comfort
8.0
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Boarding
8.1
Food
7.0
Overall
8.0
Crew
8.6
Entertainment
7.5
Comfort
8.0
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Boarding
8.1
Food
7.0
Overall
8.0
Crew
8.6
Entertainment
7.5
Comfort
8.0
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Boarding
8.1
Food
7.0
Overall
8.0
Crew
8.6
Entertainment
7.5
Comfort
8.0
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Boarding
8.1
Food
7.0
Overall
8.0
Crew
8.6
Entertainment
7.5
Comfort
8.0
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Related info for your journey
Find useful and relevant information for your journey from Michigan to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
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Alternative routes for Michigan to Missouri
See prices for flight routes from nearby airports that may be better suited for you.
Top 6 airlines flying from Michigan to Missouri
Discover the top 6 airlines that operate flights from Michigan to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 29, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$28 | Average$136 | FlexibilityNo cancel fee | On-time65% | |
| Cheapest$111 | Average$262 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$128 | Average$355 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$137 | Average$393 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$199 | Average$358 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$228 | Average$404 | FlexibilityNo cancel fee | On-time69% |