$49+ Cheap flights from Michigan to Missouri
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/26. Fares are subject to change and may not be available on all flights or dates of travel.
DTW — STL
May 11 — May 181
Round-trip
1 adult, Economy
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Find cheap flights from Michigan to Missouri with Cheapflights
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Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Cheapest flights from Michigan to MissouriExplore the most affordable flight options available from Michigan to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 11, 2026.
Explore the most affordable flight options available from Michigan to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 11, 2026.
This Kiwi.com deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/26:50 am
DTW
- STL
1 stop11h 43m
Frontier
Tue 6/236:31 pm
STL
- DTW
1 stop21h 22m
Frontier
Deal found 4/9![Frontier logo]()
$126
This Kiwi.com deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/287:04 pm
DTW
- STL
1 stop12h 46m
Frontier
Wed 4/298:23 pm
STL
- DTW
1 stop11h 42m
Frontier
Deal found 4/8![Frontier logo]()
$131
This Kiwi.com deal was found by Cheapflights users on 4/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/56:05 pm
DTW
- STL
1 stop15h 50m
Frontier
Mon 6/85:27 pm
STL
- DTW
1 stop23h 32m
Frontier
Deal found 4/10![Frontier logo]()
$136
This Frontier deal was found by Cheapflights users on 4/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/187:55 am
DTW
- STL
1 stop12h 28m
Frontier
Tue 5/196:33 pm
STL
- DTW
1 stop5h 06m
Frontier
Deal found 4/11![Frontier logo]()
$140
This Expedia deal was found by Cheapflights users on 4/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/86:20 am
DTW
- MCI
1 stop12h 09m
Frontier
Sat 5/92:34 pm
MCI
- DTW
1 stop8h 25m
Frontier
Deal found 4/10![Frontier logo]()
$140
This Kiwi.com deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/86:05 pm
DTW
- STL
1 stop15h 50m
Frontier
Mon 5/115:27 pm
STL
- DTW
1 stop18h 09m
Frontier
Deal found 4/9![Frontier logo]()
$141
This Southwest deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/66:10 am
DTW
- MCI
1 stop4h 40m
Southwest
Wed 5/139:20 am
MCI
- DTW
1 stop5h 15m
Southwest
Deal found 4/8![Southwest logo]()
$143
This Kiwi.com deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/18:49 pm
DTW
- STL
1 stop11h 01m
Frontier
Mon 5/48:23 pm
STL
- DTW
1 stop15h 13m
Frontier
Deal found 4/7![Frontier logo]()
$144
This Kiwi.com deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/57:47 am
DTW
- STL
1 stop10h 49m
Frontier
Thu 5/76:55 pm
STL
- DTW
1 stop28h 44m
Frontier
Deal found 4/6![Frontier logo]()
$147
This Kiwi.com deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/287:04 pm
DTW
- STL
1 stop12h 46m
Frontier
Thu 4/3011:21 am
STL
- DTW
1 stop6h 34m
Frontier
Deal found 4/7![Frontier logo]()
$148
This Kiwi.com deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/46:30 am
DTW
- STL
1 stop12h 03m
Multiple Airlines
Tue 6/96:31 pm
STL
- DTW
1 stop21h 22m
Multiple Airlines
Deal found 4/8![Multiple Airlines logo]()
$155
This Kiwi.com deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/57:47 am
DTW
- STL
1 stop26h 08m
Frontier
Tue 5/196:33 pm
STL
- DTW
1 stop21h 47m
Frontier
Deal found 4/6![Frontier logo]()
$158
Best flights from Michigan to MissouriDiscover carefully curated flight deals from Michigan to Missouri that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 11, 2026.
Discover carefully curated flight deals from Michigan to Missouri that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 11, 2026.
This Southwest deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/67:00 am
DTW
- STL
Nonstop1h 45m
Southwest
Wed 5/1310:30 am
STL
- DTW
Nonstop1h 30m
Southwest
Deal found 4/6![Southwest logo]()
$177
This Delta deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/212:31 pm
DTW
- STL
Nonstop1h 39m
Delta
Tue 6/2310:20 am
STL
- DTW
Nonstop1h 35m
Delta
Deal found 4/9![Delta logo]()
$187
This United Airlines deal was found by Cheapflights users on 4/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/137:45 pm
ORD
- SGF
Nonstop2h 03m
United Airlines
Sat 6/206:00 am
SGF
- ORD
Nonstop1h 48m
United Airlines
Deal found 4/10![United Airlines logo]()
$259
This Southwest deal was found by Cheapflights users on 4/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/2710:15 am
MDW
- STL
Nonstop1h 15m
Southwest
Fri 5/295:40 am
STL
- MDW
Nonstop1h 10m
Southwest
Deal found 4/10![Southwest logo]()
$187
This KAYAK deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/44:17 pm
ORD
- MCI
1 stop7h 01m
American Airlines
Fri 5/86:16 pm
MCI
- ORD
1 stop5h 32m
American Airlines
Deal found 4/6![American Airlines logo]()
$381
This Southwest deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/99:15 am
MDW
- STL
Nonstop1h 15m
Southwest
Sat 5/165:40 am
STL
- MDW
Nonstop1h 10m
Southwest
Deal found 4/8![Southwest logo]()
$191
This Delta deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/306:00 am
MDW
- STL
1 stop4h 34m
Delta
Mon 5/41:46 pm
STL
- MDW
1 stop4h 12m
Delta
Deal found 4/9![Delta logo]()
$211
This Delta deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/308:52 am
ORD
- STL
1 stop4h 13m
Delta
Mon 5/41:46 pm
STL
- ORD
1 stop6h 54m
Delta
Deal found 4/9![Delta logo]()
$211
This Southwest deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/3011:40 am
MDW
- STL
Nonstop1h 15m
Southwest
Mon 5/410:15 am
STL
- MDW
1 stop5h 35m
Southwest
Deal found 4/9![Southwest logo]()
$201
This Delta deal was found by Cheapflights users on 4/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/28:59 am
DTW
- STL
Nonstop1h 49m
Delta
Mon 5/41:46 pm
STL
- DTW
Nonstop1h 36m
Delta
Deal found 4/10![Delta logo]()
$213
This Southwest deal was found by Cheapflights users on 4/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/210:30 am
MDW
- STL
2 stops7h 40m
Southwest
Mon 5/47:20 am
STL
- MDW
Nonstop1h 10m
Southwest
Deal found 4/10![Southwest logo]()
$206
This Delta deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/216:24 am
ORD
- STL
1 stop4h 08m
Delta
Thu 5/286:21 am
STL
- ORD
2 stops6h 40m
Delta
Deal found 4/6![Delta logo]()
$216
This United Airlines deal was found by Cheapflights users on 4/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/312:40 pm
ORD
- MCI
Nonstop1h 40m
United Airlines
Mon 6/86:00 am
MCI
- ORD
Nonstop1h 58m
United Airlines
Deal found 4/11![United Airlines logo]()
$302
This Southwest deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/274:15 pm
ORD
- STL
1 stop6h 25m
Southwest
Thu 4/308:25 am
STL
- ORD
1 stop6h 35m
Southwest
Deal found 4/6![Southwest logo]()
$211
This Delta deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/35:15 am
ORD
- STL
1 stop5h 19m
Delta
Wed 5/612:23 pm
STL
- ORD
2 stops8h 17m
Delta
Deal found 4/9![Delta logo]()
$232
This United Airlines deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/237:53 pm
ORD
- MCI
Nonstop1h 49m
United Airlines
Fri 6/268:20 pm
MCI
- ORD
Nonstop1h 55m
United Airlines
Deal found 4/9![United Airlines logo]()
$317
This Southwest deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/511:35 am
MDW
- STL
2 stops6h 20m
Southwest
Tue 5/121:15 pm
STL
- MDW
2 stops6h 20m
Southwest
Deal found 4/7![Southwest logo]()
$223
This Delta deal was found by Cheapflights users on 4/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/412:31 pm
DTW
- STL
Nonstop1h 39m
Delta
Sun 6/76:30 am
STL
- DTW
Nonstop1h 34m
Delta
Deal found 4/10![Delta logo]()
$235
This United Airlines deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/72:30 pm
ORD
- MCI
Nonstop1h 54m
United Airlines
Thu 5/146:17 am
MCI
- ORD
Nonstop1h 43m
United Airlines
Deal found 4/9![United Airlines logo]()
$319
This Southwest deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/138:30 pm
MDW
- STL
Nonstop1h 15m
Southwest
Wed 6/179:30 pm
STL
- MDW
Nonstop1h 05m
Southwest
Deal found 4/7![Southwest logo]()
$227
This Delta deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/177:45 pm
DTW
- STL
1 stop13h 21m
Delta
Wed 8/266:45 am
STL
- DTW
Nonstop1h 31m
Delta
Deal found 4/9![Delta logo]()
$241
This United Airlines deal was found by Cheapflights users on 4/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/256:00 am
DTW
- SGF
1 stop5h 48m
United Airlines
Tue 4/286:50 pm
SGF
- DTW
1 stop4h 09m
United Airlines
Deal found 4/10![United Airlines logo]()
$339
This KAYAK deal was found by Cheapflights users on 4/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/146:04 am
ORD
- SGF
1 stop5h 25m
American Airlines
Thu 4/167:08 am
SGF
- ORD
1 stop8h 10m
American Airlines
Deal found 4/10![American Airlines logo]()
$468
This Southwest deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/167:20 am
DTW
- STL
Nonstop1h 40m
Southwest
Sun 5/176:00 am
STL
- DTW
1 stop5h 00m
Southwest
Deal found 4/9![Southwest logo]()
$245
This United Airlines deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/56:00 am
DTW
- SGF
1 stop5h 44m
United Airlines
Sat 7/116:55 pm
SGF
- DTW
1 stop4h 03m
United Airlines
Deal found 4/6![United Airlines logo]()
$341
This Delta deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/129:17 am
MDW
- STL
1 stop3h 52m
Delta
Tue 6/165:24 pm
STL
- MDW
1 stop4h 53m
Delta
Deal found 4/6![Delta logo]()
$257
This United Airlines deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/217:18 am
DTW
- SGF
1 stop4h 30m
United Airlines
Sat 4/253:10 pm
SGF
- DTW
2 stops7h 49m
United Airlines
Deal found 4/6![United Airlines logo]()
$344
This Southwest deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/213:35 pm
DTW
- STL
2 stops8h 20m
Southwest
Sun 5/246:50 am
STL
- DTW
1 stop3h 15m
Southwest
Deal found 4/6![Southwest logo]()
$260
This Delta deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/42:25 pm
ORD
- SGF
1 stop6h 42m
Delta
Mon 5/116:52 pm
SGF
- ORD
1 stop5h 07m
Delta
Deal found 4/6![Delta logo]()
$269
This United Airlines deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/24:38 pm
GRR
- STL
1 stop7h 58m
United Airlines
Wed 6/35:41 pm
STL
- GRR
1 stop5h 16m
United Airlines
Deal found 4/8![United Airlines logo]()
$347
Last-minute flights from Michigan to MissouriDiscover last-minute flight deals from Michigan to Missouri. Data last updated April 11, 2026 and is based on user searches.
Discover last-minute flight deals from Michigan to Missouri. Data last updated April 11, 2026 and is based on user searches.
This Frontier deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/238:43 pm
DTW
- STL
1 stop11h 07m
Frontier
Thu 4/3011:21 am
STL
- DTW
1 stop6h 34m
Frontier
Deal found 4/7![Frontier logo]()
$160
This Kiwi.com deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/287:04 pm
DTW
- STL
1 stop12h 46m
Frontier
Wed 4/298:23 pm
STL
- DTW
1 stop11h 42m
Frontier
Deal found 4/8![Frontier logo]()
$131
This Kiwi.com deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/287:04 pm
DTW
- STL
1 stop12h 46m
Frontier
Thu 4/3011:21 am
STL
- DTW
1 stop6h 34m
Frontier
Deal found 4/7![Frontier logo]()
$148
This Kiwi.com deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/18:49 pm
DTW
- STL
1 stop11h 01m
Frontier
Mon 5/48:23 pm
STL
- DTW
1 stop15h 13m
Frontier
Deal found 4/7![Frontier logo]()
$144
This Kiwi.com deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/57:47 am
DTW
- STL
1 stop10h 49m
Frontier
Thu 5/76:55 pm
STL
- DTW
1 stop28h 44m
Frontier
Deal found 4/6![Frontier logo]()
$147
This Kiwi.com deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/57:47 am
DTW
- STL
1 stop26h 08m
Frontier
Tue 5/196:33 pm
STL
- DTW
1 stop21h 47m
Frontier
Deal found 4/6![Frontier logo]()
$158
This Southwest deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/66:10 am
DTW
- MCI
1 stop4h 40m
Southwest
Wed 5/139:20 am
MCI
- DTW
1 stop5h 15m
Southwest
Deal found 4/8![Southwest logo]()
$143
This Expedia deal was found by Cheapflights users on 4/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/86:20 am
DTW
- MCI
1 stop12h 09m
Frontier
Sat 5/92:34 pm
MCI
- DTW
1 stop8h 25m
Frontier
Deal found 4/10![Frontier logo]()
$140
This Kiwi.com deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/86:05 pm
DTW
- STL
1 stop15h 50m
Frontier
Mon 5/115:27 pm
STL
- DTW
1 stop18h 09m
Frontier
Deal found 4/9![Frontier logo]()
$141
This Expedia deal was found by Cheapflights users on 4/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/86:20 am
DTW
- MCI
1 stop12h 09m
Frontier
Mon 5/112:34 pm
MCI
- DTW
1 stop8h 25m
Frontier
Deal found 4/10![Frontier logo]()
$160
This Kiwi.com deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/117:55 am
DTW
- STL
1 stop12h 28m
Frontier
Wed 5/135:27 pm
STL
- DTW
1 stop18h 37m
Frontier
Deal found 4/6![Frontier logo]()
$159
This Frontier deal was found by Cheapflights users on 4/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/187:55 am
DTW
- STL
1 stop12h 28m
Frontier
Tue 5/196:33 pm
STL
- DTW
1 stop5h 06m
Frontier
Deal found 4/11![Frontier logo]()
$140
One-way flights from Michigan to MissouriSearch for one-way flight options from Michigan to Missouri. Find affordable one-way fares based on user searches. Data last updated April 11, 2026.
Search for one-way flight options from Michigan to Missouri. Find affordable one-way fares based on user searches. Data last updated April 11, 2026.
This Southwest deal was found by Cheapflights users on 4/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/268:55 pm
MDW
- STL
Nonstop1h 15m
Southwest
Deal found 4/10![Southwest logo]()
$49
This American Airlines deal was found by Cheapflights users on 4/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/2610:40 pm
ORD
- STL
Nonstop1h 14m
American Airlines
Deal found 4/10![American Airlines logo]()
$49
This Southwest deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/61:55 pm
MDW
- STL
Nonstop1h 10m
Southwest
Deal found 4/6![Southwest logo]()
$59
This American Airlines deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/610:30 pm
ORD
- STL
Nonstop1h 16m
American Airlines
Deal found 4/8![American Airlines logo]()
$59
This Kiwi.com deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/71:59 pm
DTW
- MCI
1 stop28h 30m
Frontier
Deal found 4/7![Frontier logo]()
$63
This Southwest deal was found by Cheapflights users on 4/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/262:40 pm
ORD
- STL
1 stop7h 20m
Southwest
Deal found 4/10![Southwest logo]()
$64
This Kiwi.com deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/96:54 pm
DTW
- STL
1 stop14h 58m
Frontier
Deal found 4/8![Frontier logo]()
$65
This Kiwi.com deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/96:54 pm
DTW
- MCI
1 stop23h 27m
Frontier
Deal found 4/9![Frontier logo]()
$65
This Kiwi.com deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/2811:28 am
ORD
- STL
1 stop19h 22m
Multiple Airlines
Deal found 4/6![Multiple Airlines logo]()
$66
This Southwest deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/62:40 pm
ORD
- STL
1 stop4h 35m
Southwest
Deal found 4/6![Southwest logo]()
$69
This Kiwi.com deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/57:47 am
DTW
- STL
1 stop26h 08m
Frontier
Deal found 4/6![Frontier logo]()
$70
This Frontier deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/84:52 pm
MDW
- STL
1 stop7h 29m
Frontier
Deal found 4/6![Frontier logo]()
$70
Find flight deals from Michigan to Missouri
Keep the following information in mind while searching for Michigan to Missouri flight deals. Data was last updated April 11, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $126 (Kiwi.com) |
One-way from | $49 (Southwest) |
Popular in | February |
Cheapest in | August |
Average price | $350 |
Good round-trip deal | $347 or less |
Good one-way deal | $208 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Michigan to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 11, 2026.
Use the filters below to find and compare flights from Michigan to Missouri that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
DetroitSt. Louis
DTW - STL
DTWSTL
Detroit Metropolitan Wayne County
Wed 5/6
7:00 am-7:45 am
Nonstop1h 45m
Lambert-St Louis
Wed 5/13
10:30 am-1:00 pm
Nonstop1h 30m
$177
DetroitSt. Louis
DTW - STL
DTWSTL
Detroit Metropolitan Wayne County
Tue 6/2
12:31 pm-1:10 pm
Nonstop1h 39m
Lambert-St Louis
Tue 6/23
10:20 am-12:55 pm
Nonstop1h 35m
$187
ChicagoSt. Louis
MDW - STL
MDWSTL
Chicago Midway
Wed 5/27
10:15 am-11:30 am
Nonstop1h 15m
Lambert-St Louis
Fri 5/29
5:40 am-6:50 am
Nonstop1h 10m
$187
ChicagoSt. Louis
MDW - STL
MDWSTL
Chicago Midway
Sat 5/9
9:15 am-10:30 am
Nonstop1h 15m
Lambert-St Louis
Sat 5/16
5:40 am-6:50 am
Nonstop1h 10m
$191
ChicagoSt. Louis
MDW - STL
MDWSTL
Chicago Midway
Thu 4/30
11:40 am-12:55 pm
Nonstop1h 15m
Lambert-St Louis
Mon 5/4
10:15 am-3:50 pm
1 stop5h 35m
$201
ChicagoSt. Louis
MDW - STL
MDWSTL
Chicago Midway
Sat 5/2
10:30 am-6:10 pm
2 stops7h 40m
Lambert-St Louis
Mon 5/4
7:20 am-8:30 am
Nonstop1h 10m
$206
ChicagoSt. Louis
MDW - STL
MDWSTL
Chicago Midway
Thu 4/30
6:00 am-10:34 am
1 stop4h 34m
Lambert-St Louis
Mon 5/4
1:46 pm-5:58 pm
1 stop4h 12m
$211
ChicagoSt. Louis
ORD - STL
ORDSTL
Chicago O'Hare Intl
Thu 4/30
8:52 am-1:05 pm
1 stop4h 13m
Lambert-St Louis
Mon 5/4
1:46 pm-8:40 pm
1 stop6h 54m
$211
ChicagoSt. Louis
ORD - STL
ORDSTL
Chicago O'Hare Intl
Mon 4/27
4:15 pm-10:40 pm
1 stop6h 25m
Lambert-St Louis
Thu 4/30
8:25 am-3:00 pm
1 stop6h 35m
$211
DetroitSt. Louis
DTW - STL
DTWSTL
Detroit Metropolitan Wayne County
Sat 5/2
8:59 am-9:48 am
Nonstop1h 49m
Lambert-St Louis
Mon 5/4
1:46 pm-4:22 pm
Nonstop1h 36m
$213
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from Michigan to Missouri
Have a flexible travel schedule? Discover the best time to fly to Missouri from Michigan with our price prediction graph.
DTW-STL
DTW-MCI
MDW-STL
ORD-STL
GRR-STL
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Michigan to Missouri
USMI-USMO
DTW-STL
DTW-MCI
MDW-STL
ORD-STL
What is the cheapest month to book a flight from Michigan to Missouri?
Currently, August is the cheapest month in which you can book a flight from Michigan to Missouri (average of $39). Flying from Michigan to Missouri in January is currently the most expensive (average of $253). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from MI to MO?
Find hourly flight availability from Michigan to Missouri. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 11, 2026.
It’s typically best to fly out from Michigan to Missouri at noon. Doing so could potentially save you 22% on the flight price compared to flying in the afternoon, which is usually more expensive.
What is the cheapest day to fly from Michigan to Missouri?
Use this chart to determine the cheapest time to fly round-trip from Michigan to Missouri. Price data was last updated on April 4, 2026.
Travelers seeking maximum savings on their Michigan to Missouri flight should consider departing on Sunday at noon when fares are most often at their lowest. Tuesday mornings flights should be avoided if possible as fares are typically the most expensive at this time.
How much does it cost to fly round-trip from Michigan to Missouri?
Reviews of airlines servicing Missouri
Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated April 11, 2026.
Peruse reviews from past customers who have flown with Southwest,Delta, andUnited Airlines from Michigan to Missouri to help guide your decision. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Crew
8.6
Entertainment
7.5
Comfort
8.0
Food
7.0
Overall
8.0
Boarding
8.1
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Crew
8.6
Entertainment
7.5
Comfort
8.0
Food
7.0
Overall
8.0
Boarding
8.1
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Crew
8.6
Entertainment
7.5
Comfort
8.0
Food
7.0
Overall
8.0
Boarding
8.1
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Crew
8.6
Entertainment
7.5
Comfort
8.0
Food
7.0
Overall
8.0
Boarding
8.1
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Crew
8.6
Entertainment
7.5
Comfort
8.0
Food
7.0
Overall
8.0
Boarding
8.1
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Crew
8.6
Entertainment
7.5
Comfort
8.0
Food
7.0
Overall
8.0
Boarding
8.1
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Related info for your journey
Find useful and relevant information for your journey from Michigan to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
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Alternative routes for Michigan to Missouri
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Missouri by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Michigan to Missouri by cabin class
Find flights from Michigan to Missouri, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Michigan and Missouri flights
Browse other Michigan and Missouri flight options. Last updated on April 11, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Find a return flight route from Missouri
Find the right flight back to Michigan after your stay in Missouri
Michigan to Missouri flights
Consider these flights traveling from Michigan to Missouri.
Top 6 airlines flying from Michigan to Missouri
Discover the top 6 airlines that operate flights from Michigan to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 11, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$28 | Average$138 | FlexibilityNo cancel fee | On-time65% | |
| Cheapest$111 | Average$212 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$120 | Average$360 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$121 | Average$393 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$199 | Average$357 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$228 | Average$392 | FlexibilityNo cancel fee | On-time69% |