$49+ Cheap flights from Michigan to Missouri
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/6. Fares are subject to change and may not be available on all flights or dates of travel.
DTW — STL
May 17 — May 241
Round-trip
1 adult, Economy
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Find cheap flights from Michigan to Missouri with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Cheapest flights from Michigan to MissouriExplore the most affordable flight options available from Michigan to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 17, 2026.
Explore the most affordable flight options available from Michigan to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 17, 2026.
This Kiwi.com deal was found by Cheapflights users on 4/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/136:05 pm
DTW
- STL
1 stop23h 49m
Frontier
Wed 5/205:27 pm
STL
- DTW
1 stop6h 12m
Frontier
Deal found 4/13![Frontier logo]()
$127
This Kiwi.com deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/126:50 am
DTW
- STL
1 stop27h 05m
Frontier
Tue 5/196:33 pm
STL
- DTW
1 stop21h 47m
Frontier
Deal found 4/14![Frontier logo]()
$132
This Kiwi.com deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/101:59 pm
DTW
- STL
1 stop19h 56m
Frontier
Tue 5/126:33 pm
STL
- DTW
1 stop21h 47m
Frontier
Deal found 4/15![Frontier logo]()
$140
This Kiwi.com deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/175:40 pm
DTW
- MCI
1 stop24h 44m
Multiple Airlines
Mon 7/206:19 pm
MCI
- DTW
1 stop12h 34m
Multiple Airlines
Deal found 4/17![Multiple Airlines logo]()
$146
This Kiwi.com deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/281:59 pm
DTW
- MCI
1 stop28h 30m
Frontier
Mon 6/16:24 pm
MCI
- DTW
1 stop17h 40m
Frontier
Deal found 4/16![Frontier logo]()
$151
This Kiwi.com deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/196:50 am
DTW
- STL
1 stop11h 43m
Frontier
Wed 5/205:27 pm
STL
- DTW
1 stop6h 12m
Frontier
Deal found 4/16![Frontier logo]()
$155
This Kiwi.com deal was found by Cheapflights users on 4/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/276:20 am
DTW
- MCI
1 stop12h 09m
Frontier
Mon 6/16:24 pm
MCI
- DTW
1 stop17h 40m
Frontier
Deal found 4/13![Frontier logo]()
$155
This Frontier deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/51:31 pm
DTW
- STL
1 stop5h 05m
Frontier
Tue 5/196:33 pm
STL
- DTW
1 stop5h 06m
Frontier
Deal found 4/14![Frontier logo]()
$160
This Kiwi.com deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/206:05 pm
DTW
- STL
1 stop23h 10m
Frontier
Wed 6/35:27 pm
STL
- DTW
1 stop6h 12m
Frontier
Deal found 4/15![Frontier logo]()
$161
This Kiwi.com deal was found by Cheapflights users on 4/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/18:49 pm
DTW
- STL
1 stop11h 01m
Frontier
Mon 5/48:23 pm
STL
- DTW
1 stop15h 13m
Frontier
Deal found 4/12![Frontier logo]()
$162
This Kiwi.com deal was found by Cheapflights users on 4/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/136:05 pm
DTW
- STL
1 stop23h 49m
Multiple Airlines
Sat 5/165:27 pm
STL
- DTW
1 stop13h 25m
Multiple Airlines
Deal found 4/12![Multiple Airlines logo]()
$165
This Kiwi.com deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/71:59 pm
DTW
- STL
1 stop19h 56m
Frontier
Mon 5/115:27 pm
STL
- DTW
1 stop18h 09m
Frontier
Deal found 4/14![Frontier logo]()
$166
Best flights from Michigan to MissouriDiscover carefully curated flight deals from Michigan to Missouri that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 17, 2026.
Discover carefully curated flight deals from Michigan to Missouri that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 17, 2026.
This Southwest deal was found by Cheapflights users on 4/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/912:45 pm
MDW
- STL
Nonstop1h 15m
Southwest
Sat 5/96:55 pm
STL
- MDW
Nonstop1h 10m
Southwest
Deal found 4/12![Southwest logo]()
$191
This Delta deal was found by Cheapflights users on 4/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/1312:31 pm
DTW
- STL
Nonstop1h 39m
Delta
Wed 5/2010:19 am
STL
- DTW
Nonstop1h 31m
Delta
Deal found 4/13![Delta logo]()
$197
This United Airlines deal was found by Cheapflights users on 4/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/48:08 pm
ORD
- COU
Nonstop1h 51m
United Airlines
Sun 6/78:00 am
COU
- ORD
Nonstop1h 40m
United Airlines
Deal found 4/13![United Airlines logo]()
$239
This American Airlines deal was found by Cheapflights users on 4/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/108:20 pm
ORD
- COU
Nonstop1h 36m
American Airlines
Thu 11/127:39 pm
COU
- ORD
Nonstop1h 42m
American Airlines
Deal found 4/13![American Airlines logo]()
$239
This Southwest deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/3012:45 pm
MDW
- STL
Nonstop1h 15m
Southwest
Sat 6/65:40 am
STL
- MDW
Nonstop1h 05m
Southwest
Deal found 4/15![Southwest logo]()
$191
This Delta deal was found by Cheapflights users on 4/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/129:25 am
ORD
- STL
2 stops7h 21m
Delta
Tue 5/198:53 am
STL
- ORD
2 stops9h 12m
Delta
Deal found 4/12![Delta logo]()
$228
This Southwest deal was found by Cheapflights users on 4/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/131:40 pm
DTW
- STL
1 stop5h 15m
Southwest
Sat 5/167:00 pm
STL
- DTW
Nonstop1h 30m
Southwest
Deal found 4/12![Southwest logo]()
$215
This United Airlines deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/48:08 pm
ORD
- COU
Nonstop1h 51m
United Airlines
Sat 6/63:05 pm
COU
- ORD
Nonstop1h 41m
United Airlines
Deal found 4/15![United Airlines logo]()
$239
This American Airlines deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/157:55 pm
ORD
- COU
Nonstop1h 34m
American Airlines
Mon 5/184:28 pm
COU
- ORD
Nonstop1h 42m
American Airlines
Deal found 4/16![American Airlines logo]()
$254
This Southwest deal was found by Cheapflights users on 4/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/178:55 pm
MDW
- STL
Nonstop1h 10m
Southwest
Tue 8/258:45 pm
STL
- MDW
Nonstop1h 05m
Southwest
Deal found 4/12![Southwest logo]()
$217
This United Airlines deal was found by Cheapflights users on 4/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/138:08 pm
ORD
- COU
Nonstop1h 51m
United Airlines
Wed 6/173:05 pm
COU
- ORD
Nonstop1h 41m
United Airlines
Deal found 4/13![United Airlines logo]()
$239
This Delta deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/308:52 am
ORD
- STL
1 stop4h 13m
Delta
Sat 5/210:50 am
STL
- ORD
1 stop5h 28m
Delta
Deal found 4/14![Delta logo]()
$245
This American Airlines deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/195:34 pm
ORD
- COU
1 stop5h 12m
American Airlines
Sun 6/216:00 am
COU
- ORD
Nonstop1h 38m
American Airlines
Deal found 4/17![American Airlines logo]()
$264
This Southwest deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/78:05 am
MDW
- STL
Nonstop1h 25m
Southwest
Tue 6/95:40 am
STL
- MDW
Nonstop1h 05m
Southwest
Deal found 4/16![Southwest logo]()
$228
This Delta deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/198:15 am
ORD
- STL
1 stop4h 38m
Delta
Mon 12/144:40 pm
STL
- ORD
1 stop4h 30m
Delta
Deal found 4/14![Delta logo]()
$257
This United Airlines deal was found by Cheapflights users on 4/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/212:45 pm
ORD
- SGF
Nonstop1h 50m
United Airlines
Mon 5/46:22 pm
SGF
- ORD
Nonstop1h 43m
United Airlines
Deal found 4/13![United Airlines logo]()
$264
This American Airlines deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/302:27 pm
ORD
- COU
Nonstop1h 31m
American Airlines
Sun 5/36:00 am
COU
- ORD
Nonstop1h 43m
American Airlines
Deal found 4/16![American Airlines logo]()
$269
This Southwest deal was found by Cheapflights users on 4/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/267:45 am
MDW
- STL
1 stop5h 15m
Southwest
Tue 5/266:40 pm
STL
- MDW
1 stop3h 35m
Southwest
Deal found 4/13![Southwest logo]()
$237
This Delta deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/35:04 pm
ORD
- STL
1 stop3h 40m
Delta
Wed 5/612:23 pm
STL
- ORD
2 stops8h 17m
Delta
Deal found 4/15![Delta logo]()
$261
This United Airlines deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/71:01 pm
ORD
- STL
Nonstop1h 31m
United Airlines
Mon 5/118:30 pm
STL
- ORD
Nonstop1h 31m
United Airlines
Deal found 4/15![United Airlines logo]()
$264
This American Airlines deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/124:48 pm
ORD
- COU
1 stop5h 18m
American Airlines
Sun 8/165:17 pm
COU
- ORD
1 stop5h 53m
American Airlines
Deal found 4/16![American Airlines logo]()
$273
This Southwest deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/19:10 pm
MDW
- STL
Nonstop1h 15m
Southwest
Mon 7/62:25 pm
STL
- MDW
1 stop3h 25m
Southwest
Deal found 4/15![Southwest logo]()
$238
This United Airlines deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/111:05 pm
ORD
- COU
Nonstop1h 43m
United Airlines
Mon 5/48:00 am
COU
- ORD
Nonstop1h 30m
United Airlines
Deal found 4/15![United Airlines logo]()
$269
This Delta deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/272:00 pm
ORD
- SGF
2 stops8h 19m
Delta
Mon 6/16:49 pm
SGF
- ORD
1 stop5h 10m
Delta
Deal found 4/15![Delta logo]()
$274
This Southwest deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/311:35 am
MDW
- STL
2 stops6h 20m
Southwest
Tue 6/96:05 pm
STL
- MDW
1 stop5h 45m
Southwest
Deal found 4/14![Southwest logo]()
$239
This United Airlines deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/18:02 pm
ORD
- SGF
Nonstop2h 00m
United Airlines
Sun 5/36:00 am
SGF
- ORD
Nonstop1h 47m
United Airlines
Deal found 4/14![United Airlines logo]()
$279
This Delta deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/225:41 pm
ORD
- STL
1 stop5h 40m
Delta
Sat 5/234:00 pm
STL
- ORD
1 stop5h 46m
Delta
Deal found 4/16![Delta logo]()
$284
This United Airlines deal was found by Cheapflights users on 4/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/288:55 am
ORD
- SGF
Nonstop1h 53m
United Airlines
Sat 5/26:00 am
SGF
- ORD
Nonstop1h 47m
United Airlines
Deal found 4/12![United Airlines logo]()
$279
This Delta deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/162:21 pm
GRR
- STL
1 stop3h 55m
Delta
Wed 5/203:11 pm
STL
- GRR
1 stop6h 57m
Delta
Deal found 4/16![Delta logo]()
$286
This KAYAK deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/2912:30 pm
ORD
- SGF
1 stop4h 47m
American Airlines
Thu 4/307:34 am
SGF
- ORD
Nonstop1h 56m
American Airlines
Deal found 4/15![American Airlines logo]()
$377
Last-minute flights from Michigan to MissouriDiscover last-minute flight deals from Michigan to Missouri. Data last updated April 17, 2026 and is based on user searches.
Discover last-minute flight deals from Michigan to Missouri. Data last updated April 17, 2026 and is based on user searches.
This CheapOair deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/410:27 pm
DTW
- MCI
1 stop16h 22m
Frontier
Thu 5/72:34 pm
MCI
- DTW
1 stop8h 25m
Frontier
Deal found 4/14![Frontier logo]()
$171
This Frontier deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/51:31 pm
DTW
- STL
1 stop5h 05m
Frontier
Tue 5/196:33 pm
STL
- DTW
1 stop5h 06m
Frontier
Deal found 4/14![Frontier logo]()
$160
This Kiwi.com deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/71:59 pm
DTW
- STL
1 stop19h 56m
Frontier
Mon 5/115:27 pm
STL
- DTW
1 stop18h 09m
Frontier
Deal found 4/14![Frontier logo]()
$166
This Kiwi.com deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/101:59 pm
DTW
- STL
1 stop19h 56m
Frontier
Tue 5/126:33 pm
STL
- DTW
1 stop21h 47m
Frontier
Deal found 4/15![Frontier logo]()
$140
This Kiwi.com deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/126:50 am
DTW
- STL
1 stop27h 05m
Frontier
Tue 5/196:33 pm
STL
- DTW
1 stop21h 47m
Frontier
Deal found 4/14![Frontier logo]()
$132
This Kiwi.com deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/121:31 pm
DTW
- MCI
1 stop28h 58m
Frontier
Sat 5/162:34 pm
MCI
- DTW
1 stop8h 25m
Frontier
Deal found 4/16![Frontier logo]()
$173
This Kiwi.com deal was found by Cheapflights users on 4/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/136:05 pm
DTW
- STL
1 stop23h 49m
Frontier
Wed 5/205:27 pm
STL
- DTW
1 stop6h 12m
Frontier
Deal found 4/13![Frontier logo]()
$127
This Kiwi.com deal was found by Cheapflights users on 4/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/136:05 pm
DTW
- STL
1 stop23h 49m
Multiple Airlines
Sat 5/165:27 pm
STL
- DTW
1 stop13h 25m
Multiple Airlines
Deal found 4/12![Multiple Airlines logo]()
$165
This Kiwi.com deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/196:50 am
DTW
- STL
1 stop11h 43m
Frontier
Wed 5/205:27 pm
STL
- DTW
1 stop6h 12m
Frontier
Deal found 4/16![Frontier logo]()
$155
This Kiwi.com deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/206:05 pm
DTW
- STL
1 stop23h 10m
Frontier
Wed 6/35:27 pm
STL
- DTW
1 stop6h 12m
Frontier
Deal found 4/15![Frontier logo]()
$161
This Kiwi.com deal was found by Cheapflights users on 4/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/276:20 am
DTW
- MCI
1 stop12h 09m
Frontier
Mon 6/16:24 pm
MCI
- DTW
1 stop17h 40m
Frontier
Deal found 4/13![Frontier logo]()
$155
This Kiwi.com deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/281:59 pm
DTW
- MCI
1 stop28h 30m
Frontier
Mon 6/16:24 pm
MCI
- DTW
1 stop17h 40m
Frontier
Deal found 4/16![Frontier logo]()
$151
One-way flights from Michigan to MissouriSearch for one-way flight options from Michigan to Missouri. Find affordable one-way fares based on user searches. Data last updated April 17, 2026.
Search for one-way flight options from Michigan to Missouri. Find affordable one-way fares based on user searches. Data last updated April 17, 2026.
This Southwest deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/68:15 am
MDW
- STL
Nonstop1h 15m
Southwest
Deal found 4/14![Southwest logo]()
$49
This American Airlines deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/177:04 pm
ORD
- STL
Nonstop1h 22m
American Airlines
Deal found 4/14![American Airlines logo]()
$49
This Southwest deal was found by Cheapflights users on 4/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/1211:55 am
ORD
- STL
1 stop6h 00m
Southwest
Deal found 4/13![Southwest logo]()
$59
This Kiwi.com deal was found by Cheapflights users on 4/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/126:50 am
DTW
- STL
1 stop11h 43m
Frontier
Deal found 4/12![Frontier logo]()
$63
This Southwest deal was found by Cheapflights users on 4/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/1211:35 am
MDW
- STL
2 stops6h 20m
Southwest
Deal found 4/13![Southwest logo]()
$64
This Southwest deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/611:55 am
ORD
- STL
1 stop9h 20m
Southwest
Deal found 4/15![Southwest logo]()
$64
This Kiwi.com deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/186:05 pm
DTW
- STL
1 stop24h 28m
Frontier
Deal found 4/16![Frontier logo]()
$65
This Frontier deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/84:52 pm
MDW
- STL
1 stop7h 29m
Frontier
Deal found 4/14![Frontier logo]()
$70
This Frontier deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/127:55 am
DTW
- MCI
1 stop6h 54m
Frontier
Deal found 4/14![Frontier logo]()
$70
This Frontier deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/85:30 pm
ORD
- STL
1 stop6h 51m
Frontier
Deal found 4/14![Frontier logo]()
$70
This Kiwi.com deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/136:05 pm
DTW
- STL
1 stop23h 49m
Frontier
Deal found 4/14![Frontier logo]()
$71
This Kiwi.com deal was found by Cheapflights users on 4/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/96:00 am
MDW
- STL
1 stop11h 30m
Frontier
Deal found 4/12![Frontier logo]()
$71
Find flight deals from Michigan to Missouri
Keep the following information in mind while searching for Michigan to Missouri flight deals. Data was last updated April 17, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $127 (Kiwi.com) |
One-way from | $49 (Southwest) |
Popular in | February |
Cheapest in | August |
Average price | $389 |
Good round-trip deal | $342 or less |
Good one-way deal | $199 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Michigan to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 17, 2026.
Use the filters below to find and compare flights from Michigan to Missouri that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
ChicagoSt. Louis
MDW - STL
MDWSTL
Chicago Midway
Sat 5/9
12:45 pm-2:00 pm
Nonstop1h 15m
Lambert-St Louis
Sat 5/9
6:55 pm-8:05 pm
Nonstop1h 10m
$191
ChicagoSt. Louis
MDW - STL
MDWSTL
Chicago Midway
Sat 5/30
12:45 pm-2:00 pm
Nonstop1h 15m
Lambert-St Louis
Sat 6/6
5:40 am-6:45 am
Nonstop1h 05m
$191
DetroitSt. Louis
DTW - STL
DTWSTL
Detroit Metropolitan Wayne County
Wed 5/13
12:31 pm-1:10 pm
Nonstop1h 39m
Lambert-St Louis
Wed 5/20
10:19 am-12:50 pm
Nonstop1h 31m
$197
DetroitSt. Louis
DTW - STL
DTWSTL
Detroit Metropolitan Wayne County
Wed 5/13
1:40 pm-5:55 pm
1 stop5h 15m
Lambert-St Louis
Sat 5/16
7:00 pm-9:30 pm
Nonstop1h 30m
$215
Quickest round-trip
ChicagoSt. Louis
MDW - STL
MDWSTL
Chicago Midway
Mon 8/17
8:55 pm-10:05 pm
Nonstop1h 10m
Lambert-St Louis
Tue 8/25
8:45 pm-9:50 pm
Nonstop1h 05m
$217
ChicagoSt. Louis
ORD - STL
ORDSTL
Chicago O'Hare Intl
Tue 5/12
9:25 am-4:46 pm
2 stops7h 21m
Lambert-St Louis
Tue 5/19
8:53 am-6:05 pm
2 stops9h 12m
$228
ChicagoSt. Louis
MDW - STL
MDWSTL
Chicago Midway
Sun 6/7
8:05 am-9:30 am
Nonstop1h 25m
Lambert-St Louis
Tue 6/9
5:40 am-6:45 am
Nonstop1h 05m
$228
ChicagoSt. Louis
MDW - STL
MDWSTL
Chicago Midway
Tue 5/26
7:45 am-1:00 pm
1 stop5h 15m
Lambert-St Louis
Tue 5/26
6:40 pm-10:15 pm
1 stop3h 35m
$237
ChicagoSt. Louis
MDW - STL
MDWSTL
Chicago Midway
Wed 7/1
9:10 pm-10:25 pm
Nonstop1h 15m
Lambert-St Louis
Mon 7/6
2:25 pm-5:50 pm
1 stop3h 25m
$238
ChicagoColumbia
ORD - COU
ORDCOU
Chicago O'Hare Intl
Thu 6/4
8:08 pm-9:59 pm
Nonstop1h 51m
Columbia Regional
Sun 6/7
8:00 am-9:40 am
Nonstop1h 40m
$239
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from Michigan to Missouri
Have a flexible travel schedule? Discover the best time to fly to Missouri from Michigan with our price prediction graph.
DTW-STL
DTW-MCI
MDW-STL
ORD-COU
ORD-STL
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Michigan to Missouri
USMI-USMO
DTW-STL
DTW-MCI
MDW-STL
ORD-COU
What is the cheapest month to book a flight from Michigan to Missouri?
Currently, June is the cheapest month in which you can book a flight from Michigan to Missouri (average of $26). Flying from Michigan to Missouri in January is currently the most expensive (average of $145). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from MI to MO?
Find hourly flight availability from Michigan to Missouri. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 17, 2026.
It’s typically best to fly out from Michigan to Missouri at noon. Doing so could potentially save you 23% on the flight price compared to flying in the afternoon, which is usually more expensive.
What is the cheapest day to fly from Michigan to Missouri?
Use this chart to determine the cheapest time to fly round-trip from Michigan to Missouri. Price data was last updated on April 11, 2026.
Travelers seeking maximum savings on their Michigan to Missouri flight should consider departing on Sunday at noon when fares are most often at their lowest. Monday mornings flights should be avoided if possible as fares are typically the most expensive at this time.
Weekly flight availability from Michigan to Missouri
Explore weekly flight availability from Michigan to Missouri. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated April 17, 2026.
The most flights from USMI to USMO are scheduled on a Monday (17 on average). You will have fewer flight options on Saturday, which is when the least amount of flights are scheduled (7 on average).
How much does it cost to fly round-trip from Michigan to Missouri?
Reviews of airlines servicing Missouri
Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated April 17, 2026.
Peruse reviews from past customers who have flown with Southwest,Delta, andUnited Airlines from Michigan to Missouri to help guide your decision. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Boarding
8.1
Crew
8.6
Overall
8.0
Entertainment
7.5
Food
7.0
Comfort
8.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Boarding
8.1
Crew
8.6
Overall
8.0
Entertainment
7.5
Food
7.0
Comfort
8.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Boarding
8.1
Crew
8.6
Overall
8.0
Entertainment
7.5
Food
7.0
Comfort
8.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Boarding
8.1
Crew
8.6
Overall
8.0
Entertainment
7.5
Food
7.0
Comfort
8.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Boarding
8.1
Crew
8.6
Overall
8.0
Entertainment
7.5
Food
7.0
Comfort
8.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Boarding
8.1
Crew
8.6
Overall
8.0
Entertainment
7.5
Food
7.0
Comfort
8.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Related info for your journey
Find useful and relevant information for your journey from Michigan to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Michigan to Missouri
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Missouri by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Michigan to Missouri by cabin class
Find flights from Michigan to Missouri, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Michigan and Missouri flights
Browse other Michigan and Missouri flight options. Last updated on April 17, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Find a return flight route from Missouri
Find the right flight back to Michigan after your stay in Missouri
Michigan to Missouri flights
Consider these flights traveling from Michigan to Missouri.
Top 6 airlines flying from Michigan to Missouri
Discover the top 6 airlines that operate flights from Michigan to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 17, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$28 | Average$143 | FlexibilityNo cancel fee | On-time65% | |
| Cheapest$111 | Average$211 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$120 | Average$364 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$121 | Average$391 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$199 | Average$357 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$228 | Average$391 | FlexibilityNo cancel fee | On-time69% |