$65+ Cheap flights from Michigan to Missouri
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/18. Fares are subject to change and may not be available on all flights or dates of travel.
DTW — STL
May 23 — May 301
Round-trip
1 adult, Economy
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Find cheap flights from Michigan to Missouri with Cheapflights
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Cheapest flights from Michigan to MissouriExplore the most affordable flight options available from Michigan to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 23, 2026.
Explore the most affordable flight options available from Michigan to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 23, 2026.
This Kiwi.com deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/175:40 pm
DTW
- MCI
1 stop24h 44m
Frontier
Wed 7/226:19 pm
MCI
- DTW
1 stop29h 23m
Frontier
Deal found 4/19![Frontier logo]()
$126
This Kiwi.com deal was found by Cheapflights users on 4/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/121:31 pm
DTW
- STL
1 stop20h 24m
Frontier
Tue 5/196:33 pm
STL
- DTW
1 stop21h 47m
Frontier
Deal found 4/18![Frontier logo]()
$132
This Expedia deal was found by Cheapflights users on 4/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/97:55 am
DTW
- STL
1 stop12h 28m
Frontier
Tue 5/126:33 pm
STL
- DTW
1 stop5h 06m
Frontier
Deal found 4/18![Frontier logo]()
$140
This Frontier deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/127:55 am
DTW
- MCI
1 stop6h 54m
Frontier
Wed 5/132:34 pm
MCI
- DTW
1 stop8h 25m
Frontier
Deal found 4/20![Frontier logo]()
$140
This Kiwi.com deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/156:15 am
DTW
- MCI
1 stop12h 09m
Multiple Airlines
Wed 7/226:19 pm
MCI
- DTW
1 stop29h 23m
Multiple Airlines
Deal found 4/19![Multiple Airlines logo]()
$146
This Kiwi.com deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/197:55 am
DTW
- MCI
1 stop6h 54m
Frontier
Tue 5/262:34 pm
MCI
- DTW
1 stop8h 25m
Frontier
Deal found 4/21![Frontier logo]()
$151
This Expedia deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/177:55 am
DTW
- STL
1 stop12h 28m
Frontier
Wed 5/205:27 pm
STL
- DTW
1 stop6h 12m
Frontier
Deal found 4/19![Frontier logo]()
$160
This Expedia deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/127:55 am
DTW
- MCI
1 stop6h 54m
Frontier
Thu 5/142:34 pm
MCI
- DTW
1 stop21h 01m
Frontier
Deal found 4/20![Frontier logo]()
$160
This Frontier deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/117:55 am
DTW
- MCI
1 stop6h 54m
Frontier
Wed 5/132:34 pm
MCI
- DTW
1 stop8h 25m
Frontier
Deal found 4/20![Frontier logo]()
$161
This Kiwi.com deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/186:15 am
DTW
- MCI
1 stop12h 09m
Multiple Airlines
Wed 7/226:19 pm
MCI
- DTW
1 stop29h 23m
Multiple Airlines
Deal found 4/19![Multiple Airlines logo]()
$162
This Expedia deal was found by Cheapflights users on 4/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/1812:44 pm
DTW
- STL
1 stop12h 37m
Frontier
Mon 5/254:19 pm
STL
- DTW
1 stop18h 41m
Frontier
Deal found 4/18![Frontier logo]()
$165
This Frontier deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/217:55 am
DTW
- STL
1 stop12h 28m
Frontier
Mon 5/255:27 pm
STL
- DTW
1 stop6h 12m
Frontier
Deal found 4/20![Frontier logo]()
$166
Best flights from Michigan to MissouriDiscover carefully curated flight deals from Michigan to Missouri that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 23, 2026.
Discover carefully curated flight deals from Michigan to Missouri that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 23, 2026.
This Southwest deal was found by Cheapflights users on 4/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/215:35 am
DTW
- STL
1 stop6h 15m
Southwest
Tue 5/262:30 pm
STL
- DTW
1 stop6h 05m
Southwest
Deal found 4/18![Southwest logo]()
$225
This Delta deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/209:49 am
ORD
- STL
1 stop6h 21m
Delta
Wed 5/2711:25 am
STL
- ORD
2 stops8h 49m
Delta
Deal found 4/22![Delta logo]()
$238
This United Airlines deal was found by Cheapflights users on 4/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/78:08 pm
ORD
- COU
Nonstop1h 51m
United Airlines
Mon 8/105:00 am
COU
- ORD
Nonstop1h 41m
United Airlines
Deal found 4/18![United Airlines logo]()
$239
This American Airlines deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/224:25 pm
ORD
- COU
Nonstop1h 37m
American Airlines
Mon 5/256:32 pm
COU
- ORD
Nonstop1h 50m
American Airlines
Deal found 4/20![American Airlines logo]()
$239
This Delta deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/197:07 am
ORD
- STL
1 stop5h 15m
Delta
Wed 5/206:21 am
STL
- ORD
2 stops6h 40m
Delta
Deal found 4/21![Delta logo]()
$238
This United Airlines deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/79:15 am
ORD
- COU
Nonstop1h 33m
United Airlines
Tue 7/145:00 am
COU
- ORD
Nonstop1h 41m
United Airlines
Deal found 4/21![United Airlines logo]()
$239
This American Airlines deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/148:12 am
ORD
- COU
Nonstop1h 31m
American Airlines
Sat 5/166:00 am
COU
- ORD
Nonstop1h 43m
American Airlines
Deal found 4/21![American Airlines logo]()
$239
This Southwest deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/289:00 am
MDW
- STL
Nonstop1h 15m
Southwest
Mon 6/14:40 pm
STL
- MDW
Nonstop1h 10m
Southwest
Deal found 4/20![Southwest logo]()
$261
This United Airlines deal was found by Cheapflights users on 4/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/39:15 pm
ORD
- COU
Nonstop1h 51m
United Airlines
Sat 6/65:00 am
COU
- ORD
Nonstop1h 41m
United Airlines
Deal found 4/18![United Airlines logo]()
$239
This American Airlines deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/208:00 am
ORD
- SGF
Nonstop1h 51m
American Airlines
Wed 5/277:11 am
SGF
- ORD
Nonstop2h 01m
American Airlines
Deal found 4/22![American Airlines logo]()
$249
This United Airlines deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/98:08 pm
ORD
- COU
Nonstop1h 51m
United Airlines
Sun 7/128:00 am
COU
- ORD
Nonstop1h 40m
United Airlines
Deal found 4/22![United Airlines logo]()
$239
This Southwest deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/187:00 am
DTW
- STL
Nonstop1h 45m
Southwest
Wed 5/205:35 am
STL
- DTW
1 stop3h 10m
Southwest
Deal found 4/21![Southwest logo]()
$264
This Delta deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/205:30 am
ORD
- SGF
1 stop5h 57m
Delta
Wed 5/276:49 pm
SGF
- ORD
1 stop5h 10m
Delta
Deal found 4/22![Delta logo]()
$269
This United Airlines deal was found by Cheapflights users on 4/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/64:10 pm
ORD
- COU
Nonstop1h 35m
United Airlines
Sun 9/133:05 pm
COU
- ORD
Nonstop1h 43m
United Airlines
Deal found 4/18![United Airlines logo]()
$239
This Southwest deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/137:00 am
DTW
- STL
Nonstop1h 45m
Southwest
Sat 5/165:40 am
STL
- DTW
2 stops8h 20m
Southwest
Deal found 4/21![Southwest logo]()
$269
This Delta deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/38:15 am
ORD
- SGF
1 stop6h 30m
Delta
Sun 9/611:40 am
SGF
- ORD
1 stop6h 59m
Delta
Deal found 4/21![Delta logo]()
$284
This United Airlines deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/249:15 am
ORD
- COU
Nonstop1h 33m
United Airlines
Sun 6/2811:23 am
COU
- ORD
Nonstop1h 42m
United Airlines
Deal found 4/23![United Airlines logo]()
$239
This Southwest deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/148:55 am
MDW
- STL
Nonstop1h 15m
Southwest
Mon 5/185:40 am
STL
- MDW
Nonstop1h 10m
Southwest
Deal found 4/20![Southwest logo]()
$277
This United Airlines deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/59:15 am
ORD
- COU
Nonstop1h 33m
United Airlines
Sat 6/611:23 am
COU
- ORD
Nonstop1h 42m
United Airlines
Deal found 4/20![United Airlines logo]()
$239
This Delta deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/106:05 am
MDW
- STL
1 stop6h 29m
Delta
Sat 6/136:21 am
STL
- MDW
1 stop6h 48m
Delta
Deal found 4/22![Delta logo]()
$295
This Southwest deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/287:00 am
DTW
- STL
Nonstop1h 45m
Southwest
Mon 6/111:50 am
STL
- DTW
Nonstop1h 30m
Southwest
Deal found 4/20![Southwest logo]()
$279
This KAYAK deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/3111:17 am
ORD
- MCI
Nonstop1h 50m
American Airlines
Thu 6/45:15 am
MCI
- ORD
Nonstop1h 51m
American Airlines
Deal found 4/21![American Airlines logo]()
$354
This United Airlines deal was found by Cheapflights users on 4/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/211:00 pm
ORD
- SGF
Nonstop1h 57m
United Airlines
Tue 7/76:55 pm
SGF
- ORD
Nonstop1h 53m
United Airlines
Deal found 4/18![United Airlines logo]()
$249
This Southwest deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/192:00 pm
ORD
- MCI
1 stop7h 05m
Southwest
Wed 5/207:15 am
MCI
- ORD
1 stop8h 50m
Southwest
Deal found 4/22![Southwest logo]()
$282
This Delta deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/2211:09 am
ORD
- STL
1 stop6h 07m
Delta
Sat 5/234:00 pm
STL
- ORD
1 stop5h 46m
Delta
Deal found 4/21![Delta logo]()
$318
This American Airlines deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/226:55 am
ORD
- SGF
1 stop5h 57m
American Airlines
Fri 5/296:43 pm
SGF
- ORD
1 stop5h 59m
American Airlines
Deal found 4/22![American Airlines logo]()
$356
This United Airlines deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/157:45 pm
ORD
- COU
Nonstop1h 35m
United Airlines
Sun 10/188:00 am
COU
- ORD
Nonstop1h 33m
United Airlines
Deal found 4/19![United Airlines logo]()
$254
This Southwest deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/175:45 am
GRR
- MCI
1 stop6h 45m
Southwest
Wed 8/192:05 pm
MCI
- GRR
2 stops7h 45m
Southwest
Deal found 4/22![Southwest logo]()
$282
This Delta deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/66:15 am
DTW
- SGF
1 stop6h 07m
Delta
Thu 6/116:58 pm
SGF
- DTW
1 stop5h 00m
Delta
Deal found 4/19![Delta logo]()
$324
This United Airlines deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/79:15 am
ORD
- COU
Nonstop1h 40m
United Airlines
Wed 5/138:00 am
COU
- ORD
Nonstop1h 30m
United Airlines
Deal found 4/19![United Airlines logo]()
$254
Last-minute flights from Michigan to MissouriDiscover last-minute flight deals from Michigan to Missouri. Data last updated April 23, 2026 and is based on user searches.
Discover last-minute flight deals from Michigan to Missouri. Data last updated April 23, 2026 and is based on user searches.
This Frontier deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/57:47 am
DTW
- STL
1 stop10h 49m
Frontier
Tue 5/196:33 pm
STL
- DTW
1 stop5h 06m
Frontier
Deal found 4/20![Frontier logo]()
$180
This Frontier deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/57:55 am
DTW
- MCI
1 stop6h 54m
Frontier
Sat 5/92:34 pm
MCI
- DTW
1 stop8h 25m
Frontier
Deal found 4/20![Frontier logo]()
$180
This Expedia deal was found by Cheapflights users on 4/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/97:55 am
DTW
- STL
1 stop12h 28m
Frontier
Tue 5/126:33 pm
STL
- DTW
1 stop5h 06m
Frontier
Deal found 4/18![Frontier logo]()
$140
This Frontier deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/117:55 am
DTW
- MCI
1 stop6h 54m
Frontier
Wed 5/132:34 pm
MCI
- DTW
1 stop8h 25m
Frontier
Deal found 4/20![Frontier logo]()
$161
This Kiwi.com deal was found by Cheapflights users on 4/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/121:31 pm
DTW
- STL
1 stop20h 24m
Frontier
Tue 5/196:33 pm
STL
- DTW
1 stop21h 47m
Frontier
Deal found 4/18![Frontier logo]()
$132
This Frontier deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/127:55 am
DTW
- MCI
1 stop6h 54m
Frontier
Wed 5/132:34 pm
MCI
- DTW
1 stop8h 25m
Frontier
Deal found 4/20![Frontier logo]()
$140
This Expedia deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/127:55 am
DTW
- MCI
1 stop6h 54m
Frontier
Thu 5/142:34 pm
MCI
- DTW
1 stop21h 01m
Frontier
Deal found 4/20![Frontier logo]()
$160
This Expedia deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/177:55 am
DTW
- STL
1 stop12h 28m
Frontier
Wed 5/205:27 pm
STL
- DTW
1 stop6h 12m
Frontier
Deal found 4/19![Frontier logo]()
$160
This Expedia deal was found by Cheapflights users on 4/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/1812:44 pm
DTW
- STL
1 stop12h 37m
Frontier
Mon 5/254:19 pm
STL
- DTW
1 stop18h 41m
Frontier
Deal found 4/18![Frontier logo]()
$165
This Kiwi.com deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/197:55 am
DTW
- MCI
1 stop6h 54m
Frontier
Tue 5/262:34 pm
MCI
- DTW
1 stop8h 25m
Frontier
Deal found 4/21![Frontier logo]()
$151
This Frontier deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/217:55 am
DTW
- STL
1 stop12h 28m
Frontier
Mon 5/255:27 pm
STL
- DTW
1 stop6h 12m
Frontier
Deal found 4/20![Frontier logo]()
$166
This Frontier deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/281:20 pm
DTW
- STL
1 stop7h 03m
Frontier
Mon 6/14:19 pm
STL
- DTW
1 stop18h 41m
Frontier
Deal found 4/21![Frontier logo]()
$181
One-way flights from Michigan to MissouriSearch for one-way flight options from Michigan to Missouri. Find affordable one-way fares based on user searches. Data last updated April 23, 2026.
Search for one-way flight options from Michigan to Missouri. Find affordable one-way fares based on user searches. Data last updated April 23, 2026.
This Kiwi.com deal was found by Cheapflights users on 4/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/186:05 pm
DTW
- STL
1 stop24h 28m
Frontier
Deal found 4/18![Frontier logo]()
$65
This Kiwi.com deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/175:40 pm
DTW
- MCI
1 stop24h 44m
Frontier
Deal found 4/19![Frontier logo]()
$65
This Priceline deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/191:31 pm
DTW
- STL
1 stop5h 02m
Frontier
Deal found 4/20![Frontier logo]()
$70
This Frontier deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/1912:24 pm
MDW
- STL
1 stop5h 09m
Frontier
Deal found 4/21![Frontier logo]()
$70
This Frontier deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/197:55 am
DTW
- MCI
1 stop6h 54m
Frontier
Deal found 4/20![Frontier logo]()
$70
This Frontier deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/155:30 pm
ORD
- STL
1 stop6h 51m
Frontier
Deal found 4/19![Frontier logo]()
$70
This Priceline deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/184:52 pm
MDW
- STL
1 stop7h 29m
Frontier
Deal found 4/20![Frontier logo]()
$75
This Expedia deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/146:00 am
MDW
- STL
1 stop10h 54m
Frontier
Deal found 4/21![Frontier logo]()
$76
This Frontier deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/136:00 am
DTW
- MCI
1 stop12h 29m
Frontier
Deal found 4/22![Frontier logo]()
$76
This Frontier deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/196:55 am
ORD
- STL
1 stop10h 38m
Frontier
Deal found 4/20![Frontier logo]()
$76
This Frontier deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/126:55 am
ORD
- STL
1 stop10h 38m
Frontier
Deal found 4/19![Frontier logo]()
$77
This Kiwi.com deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/141:59 pm
DTW
- STL
1 stop19h 56m
Frontier
Deal found 4/19![Frontier logo]()
$82
Find flight deals from Michigan to Missouri
Keep the following information in mind while searching for Michigan to Missouri flight deals. Data was last updated April 23, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $126 (Kiwi.com) |
One-way from | $65 (Kiwi.com) |
Popular in | April |
Cheapest in | August |
Average price | $468 |
Good round-trip deal | $350 or less |
Good one-way deal | $189 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Michigan to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 23, 2026.
Use the filters below to find and compare flights from Michigan to Missouri that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
DetroitSt. Louis
DTW - STL
DTWSTL
Detroit Metropolitan Wayne County
Thu 5/21
5:35 am-10:50 am
1 stop6h 15m
Lambert-St Louis
Tue 5/26
2:30 pm-9:35 pm
1 stop6h 05m
$225
ChicagoSt. Louis
ORD - STL
ORDSTL
Chicago O'Hare Intl
Wed 5/20
9:49 am-4:10 pm
1 stop6h 21m
Lambert-St Louis
Wed 5/27
11:25 am-8:14 pm
2 stops8h 49m
$238
ChicagoSt. Louis
ORD - STL
ORDSTL
Chicago O'Hare Intl
Tue 5/19
7:07 am-12:22 pm
1 stop5h 15m
Lambert-St Louis
Wed 5/20
6:21 am-1:01 pm
2 stops6h 40m
$238
ChicagoColumbia
ORD - COU
ORDCOU
Chicago O'Hare Intl
Fri 8/7
8:08 pm-9:59 pm
Nonstop1h 51m
Columbia Regional
Mon 8/10
5:00 am-6:41 am
Nonstop1h 41m
$239
ChicagoColumbia
ORD - COU
ORDCOU
Chicago O'Hare Intl
Fri 5/22
4:25 pm-6:02 pm
Nonstop1h 37m
Columbia Regional
Mon 5/25
6:32 pm-8:22 pm
Nonstop1h 50m
$239
ChicagoColumbia
ORD - COU
ORDCOU
Chicago O'Hare Intl
Tue 7/7
9:15 am-10:48 am
Nonstop1h 33m
Columbia Regional
Tue 7/14
5:00 am-6:41 am
Nonstop1h 41m
$239
ChicagoColumbia
ORD - COU
ORDCOU
Chicago O'Hare Intl
Thu 5/14
8:12 am-9:43 am
Nonstop1h 31m
Columbia Regional
Sat 5/16
6:00 am-7:43 am
Nonstop1h 43m
$239
ChicagoColumbia
ORD - COU
ORDCOU
Chicago O'Hare Intl
Wed 6/3
9:15 pm-11:06 pm
Nonstop1h 51m
Columbia Regional
Sat 6/6
5:00 am-6:41 am
Nonstop1h 41m
$239
ChicagoColumbia
ORD - COU
ORDCOU
Chicago O'Hare Intl
Thu 7/9
8:08 pm-9:59 pm
Nonstop1h 51m
Columbia Regional
Sun 7/12
8:00 am-9:40 am
Nonstop1h 40m
$239
ChicagoColumbia
ORD - COU
ORDCOU
Chicago O'Hare Intl
Sun 9/6
4:10 pm-5:45 pm
Nonstop1h 35m
Columbia Regional
Sun 9/13
3:05 pm-4:48 pm
Nonstop1h 43m
$239
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from Michigan to Missouri
Have a flexible travel schedule? Discover the best time to fly to Missouri from Michigan with our price prediction graph.
DTW-STL
ORD-STL
ORD-COU
MDW-STL
ORD-SGF
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Michigan to Missouri
USMI-USMO
DTW-STL
ORD-STL
ORD-COU
MDW-STL
What is the cheapest month to book a flight from Michigan to Missouri?
Currently, June is the cheapest month in which you can book a flight from Michigan to Missouri (average of $26). Flying from Michigan to Missouri in January is currently the most expensive (average of $145). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from MI to MO?
Find hourly flight availability from Michigan to Missouri. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 23, 2026.
It’s typically best to fly out from Michigan to Missouri at noon. Doing so could potentially save you 23% on the flight price compared to flying in the afternoon, which is usually more expensive.
What is the cheapest day to fly from Michigan to Missouri?
Use this chart to determine the cheapest time to fly round-trip from Michigan to Missouri. Price data was last updated on April 18, 2026.
Travelers seeking maximum savings on their Michigan to Missouri flight should consider departing on Sunday at noon when fares are most often at their lowest. Tuesday mornings flights should be avoided if possible as fares are typically the most expensive at this time.
Weekly flight availability from Michigan to Missouri
Explore weekly flight availability from Michigan to Missouri. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated April 23, 2026.
The most flights from USMI to USMO are scheduled on a Monday (17 on average). You will have fewer flight options on Saturday, which is when the least amount of flights are scheduled (8 on average).
How much does it cost to fly round-trip from Michigan to Missouri?
Reviews of airlines servicing Missouri
Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated April 23, 2026.
Peruse reviews from past customers who have flown with Southwest,Delta, andUnited Airlines from Michigan to Missouri to help guide your decision. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Comfort
8.0
Boarding
8.1
Overall
8.0
Crew
8.6
Entertainment
7.5
Food
7.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Comfort
8.0
Boarding
8.1
Overall
8.0
Crew
8.6
Entertainment
7.5
Food
7.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Comfort
8.0
Boarding
8.1
Overall
8.0
Crew
8.6
Entertainment
7.5
Food
7.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Comfort
8.0
Boarding
8.1
Overall
8.0
Crew
8.6
Entertainment
7.5
Food
7.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Comfort
8.0
Boarding
8.1
Overall
8.0
Crew
8.6
Entertainment
7.5
Food
7.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Comfort
8.0
Boarding
8.1
Overall
8.0
Crew
8.6
Entertainment
7.5
Food
7.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Related info for your journey
Find useful and relevant information for your journey from Michigan to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
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Alternative routes for Michigan to Missouri
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Missouri by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Michigan to Missouri by cabin class
Find flights from Michigan to Missouri, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Michigan and Missouri flights
Browse other Michigan and Missouri flight options. Last updated on April 23, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Find a return flight route from Missouri
Find the right flight back to Michigan after your stay in Missouri
Michigan to Missouri flights
Consider these flights traveling from Michigan to Missouri.
Top 6 airlines flying from Michigan to Missouri
Discover the top 6 airlines that operate flights from Michigan to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 23, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$28 | Average$149 | FlexibilityNo cancel fee | On-time65% | |
| Cheapest$111 | Average$211 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$120 | Average$374 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$137 | Average$390 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$199 | Average$350 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$228 | Average$394 | FlexibilityNo cancel fee | On-time69% |