$69+ Cheap flights from Michigan to Missouri
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/15. Fares are subject to change and may not be available on all flights or dates of travel.
DTW — MCI
iun 29 — iul 61
Round-trip
1 adult, Economy
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Cheapest flights from Michigan to MissouriExplore the most affordable flight options available from Michigan to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on mai 30, 2026.
Explore the most affordable flight options available from Michigan to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on mai 30, 2026.
This United Airlines deal was found by Cheapflights users on 5/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Ma 6/167:05 am
DTW
- STL
1 stop6h 06m
United Airlines
Sâ 6/207:05 pm
STL
- DTW
1 stop3h 52m
United Airlines
Deal found 5/25![United Airlines logo]()
$172
This Delta deal was found by Cheapflights users on 5/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Vi 7/174:45 pm
DTW
- STL
Nonstop1h 39m
Delta
Vi 7/246:30 am
STL
- DTW
Nonstop1h 34m
Delta
Deal found 5/28![Delta logo]()
$177
This Southwest deal was found by Cheapflights users on 5/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Vi 7/35:50 am
DTW
- STL
2 stops13h 40m
Southwest
Ma 7/74:00 pm
STL
- DTW
1 stop3h 25m
Southwest
Deal found 5/25![Southwest logo]()
$188
This Southwest deal was found by Cheapflights users on 5/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Ma 6/167:05 am
DTW
- STL
Nonstop1h 35m
Southwest
Sâ 6/204:40 pm
STL
- DTW
1 stop4h 45m
Southwest
Deal found 5/25![Southwest logo]()
$193
This United Airlines deal was found by Cheapflights users on 5/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Ma 6/237:05 am
DTW
- STL
1 stop6h 06m
United Airlines
Ma 6/235:29 pm
STL
- DTW
1 stop5h 28m
United Airlines
Deal found 5/27![United Airlines logo]()
$198
This United Airlines deal was found by Cheapflights users on 5/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mi 6/2411:00 am
DTW
- STL
1 stop5h 46m
United Airlines
Mi 7/15:33 pm
STL
- DTW
1 stop3h 46m
United Airlines
Deal found 5/27![United Airlines logo]()
$203
This United Airlines deal was found by Cheapflights users on 5/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Jo 6/187:05 am
DTW
- STL
1 stop6h 06m
United Airlines
Du 6/215:29 pm
STL
- DTW
1 stop3h 50m
United Airlines
Deal found 5/28![United Airlines logo]()
$205
This United Airlines deal was found by Cheapflights users on 5/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Ma 7/285:30 am
DTW
- STL
1 stop4h 09m
United Airlines
Vi 7/317:05 pm
STL
- DTW
1 stop3h 49m
United Airlines
Deal found 5/28![United Airlines logo]()
$209
This Delta deal was found by Cheapflights users on 5/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Jo 8/277:40 pm
DTW
- STL
1 stop5h 18m
Delta
Du 8/306:25 pm
STL
- DTW
Nonstop1h 35m
Delta
Deal found 5/28![Delta logo]()
$216
This Delta deal was found by Cheapflights users on 5/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mi 9/29:00 am
DTW
- STL
Nonstop1h 37m
Delta
Sâ 9/57:00 am
STL
- DTW
1 stop8h 04m
Delta
Deal found 5/26![Delta logo]()
$217
This Delta deal was found by Cheapflights users on 5/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Vi 10/98:45 pm
DTW
- MCI
1 stop13h 50m
Delta
Lu 10/126:42 pm
MCI
- DTW
1 stop13h 46m
Delta
Deal found 5/26![Delta logo]()
$225
This United Airlines deal was found by Cheapflights users on 5/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Jo 7/21:15 pm
ORD
- COU
Nonstop1h 35m
United Airlines
Lu 7/610:49 am
COU
- ORD
Nonstop1h 41m
United Airlines
Deal found 5/27![United Airlines logo]()
$239
Best flights from Michigan to MissouriDiscover carefully curated flight deals from Michigan to Missouri that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated mai 30, 2026.
Discover carefully curated flight deals from Michigan to Missouri that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated mai 30, 2026.
This Delta deal was found by Cheapflights users on 5/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Jo 7/98:50 am
DTW
- STL
Nonstop1h 41m
Delta
Lu 7/136:09 pm
STL
- DTW
Nonstop1h 35m
Delta
Deal found 5/25![Delta logo]()
$177
This Southwest deal was found by Cheapflights users on 5/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Ma 8/2512:55 pm
DTW
- STL
2 stops8h 05m
Southwest
Ma 9/14:45 pm
STL
- DTW
1 stop3h 45m
Southwest
Deal found 5/26![Southwest logo]()
$208
This United Airlines deal was found by Cheapflights users on 5/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Jo 7/98:40 am
ORD
- COU
Nonstop1h 33m
United Airlines
Du 7/128:00 am
COU
- ORD
Nonstop1h 40m
United Airlines
Deal found 5/27![United Airlines logo]()
$239
This American Airlines deal was found by Cheapflights users on 5/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Jo 7/28:29 am
ORD
- COU
Nonstop1h 32m
American Airlines
Sâ 7/411:45 am
COU
- ORD
1 stop8h 46m
American Airlines
Deal found 5/24![American Airlines logo]()
$248
This Delta deal was found by Cheapflights users on 5/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mi 6/244:41 pm
DTW
- STL
Nonstop1h 42m
Delta
Du 6/286:30 am
STL
- DTW
Nonstop1h 34m
Delta
Deal found 5/25![Delta logo]()
$177
This Delta deal was found by Cheapflights users on 5/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Vi 7/178:50 am
DTW
- STL
Nonstop1h 41m
Delta
Du 7/196:30 am
STL
- DTW
Nonstop1h 34m
Delta
Deal found 5/27![Delta logo]()
$177
This Southwest deal was found by Cheapflights users on 5/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mi 7/227:05 am
DTW
- STL
Nonstop1h 35m
Southwest
Mi 7/227:40 pm
STL
- DTW
Nonstop1h 35m
Southwest
Deal found 5/25![Southwest logo]()
$209
This Delta deal was found by Cheapflights users on 5/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Jo 7/168:50 am
DTW
- STL
Nonstop1h 41m
Delta
Lu 7/206:09 pm
STL
- DTW
Nonstop1h 35m
Delta
Deal found 5/27![Delta logo]()
$177
This Delta deal was found by Cheapflights users on 5/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sâ 8/18:50 am
DTW
- STL
Nonstop1h 41m
Delta
Lu 8/36:30 am
STL
- DTW
Nonstop1h 34m
Delta
Deal found 5/26![Delta logo]()
$177
This United Airlines deal was found by Cheapflights users on 5/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Jo 7/21:15 pm
ORD
- COU
Nonstop1h 35m
United Airlines
Lu 7/610:49 am
COU
- ORD
Nonstop1h 41m
United Airlines
Deal found 5/27![United Airlines logo]()
$239
This American Airlines deal was found by Cheapflights users on 5/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Jo 7/26:00 am
GRR
- STL
1 stop3h 31m
American Airlines
Lu 7/67:56 pm
STL
- GRR
1 stop3h 40m
American Airlines
Deal found 5/29![American Airlines logo]()
$255
This Delta deal was found by Cheapflights users on 5/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Jo 7/238:50 am
DTW
- STL
Nonstop1h 41m
Delta
Vi 7/316:30 am
STL
- DTW
Nonstop1h 34m
Delta
Deal found 5/26![Delta logo]()
$177
This United Airlines deal was found by Cheapflights users on 5/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Vi 7/248:40 am
ORD
- COU
Nonstop1h 33m
United Airlines
Lu 7/273:25 pm
COU
- ORD
Nonstop1h 40m
United Airlines
Deal found 5/25![United Airlines logo]()
$239
This Southwest deal was found by Cheapflights users on 5/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sâ 6/271:20 pm
DTW
- STL
2 stops9h 25m
Southwest
Sâ 7/47:00 am
STL
- DTW
1 stop4h 35m
Southwest
Deal found 5/28![Southwest logo]()
$243
This United Airlines deal was found by Cheapflights users on 5/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Jo 7/28:40 am
ORD
- COU
Nonstop1h 33m
United Airlines
Sâ 7/410:49 am
COU
- ORD
Nonstop1h 41m
United Airlines
Deal found 5/24![United Airlines logo]()
$239
This Southwest deal was found by Cheapflights users on 5/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Jo 6/187:50 am
MDW
- STL
Nonstop1h 20m
Southwest
Ma 6/2310:15 am
STL
- MDW
1 stop5h 40m
Southwest
Deal found 5/25![Southwest logo]()
$258
This KAYAK deal was found by Cheapflights users on 5/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Lu 6/1511:45 am
ORD
- STL
Nonstop1h 27m
American Airlines
Mi 6/177:03 am
STL
- ORD
Nonstop1h 27m
American Airlines
Deal found 5/27![American Airlines logo]()
$303
This United Airlines deal was found by Cheapflights users on 5/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Jo 7/21:15 pm
ORD
- COU
Nonstop1h 35m
United Airlines
Du 7/58:00 am
COU
- ORD
Nonstop1h 40m
United Airlines
Deal found 5/28![United Airlines logo]()
$254
This Southwest deal was found by Cheapflights users on 5/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Vi 6/197:50 am
MDW
- STL
Nonstop1h 20m
Southwest
Ma 6/236:15 pm
STL
- MDW
1 stop5h 50m
Southwest
Deal found 5/29![Southwest logo]()
$258
This Delta deal was found by Cheapflights users on 5/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sâ 8/229:00 am
DTW
- STL
Nonstop1h 37m
Delta
Sâ 8/295:42 pm
STL
- DTW
1 stop3h 59m
Delta
Deal found 5/29![Delta logo]()
$218
This American Airlines deal was found by Cheapflights users on 5/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Ma 9/299:07 pm
GRR
- STL
1 stop4h 20m
American Airlines
Vi 10/25:00 am
STL
- GRR
1 stop3h 22m
American Airlines
Deal found 5/28![American Airlines logo]()
$308
This United Airlines deal was found by Cheapflights users on 5/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sâ 7/48:50 am
ORD
- SGF
Nonstop1h 54m
United Airlines
Lu 7/66:34 pm
SGF
- ORD
Nonstop1h 55m
United Airlines
Deal found 5/29![United Airlines logo]()
$264
This Southwest deal was found by Cheapflights users on 5/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Ma 7/75:30 am
GRR
- STL
1 stop7h 00m
Southwest
Mi 7/83:10 pm
STL
- GRR
2 stops7h 45m
Southwest
Deal found 5/28![Southwest logo]()
$282
This United Airlines deal was found by Cheapflights users on 5/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Jo 7/94:00 pm
ORD
- SGF
Nonstop1h 53m
United Airlines
Ma 7/146:34 pm
SGF
- ORD
Nonstop1h 55m
United Airlines
Deal found 5/26![United Airlines logo]()
$280
This Delta deal was found by Cheapflights users on 5/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sâ 6/273:41 pm
GRR
- STL
1 stop5h 58m
Delta
Lu 6/296:30 am
STL
- GRR
1 stop5h 50m
Delta
Deal found 5/27![Delta logo]()
$255
This Southwest deal was found by Cheapflights users on 5/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Jo 7/22:45 pm
GRR
- STL
2 stops9h 00m
Southwest
Lu 7/66:30 pm
STL
- GRR
1 stop3h 55m
Southwest
Deal found 5/29![Southwest logo]()
$295
This Delta deal was found by Cheapflights users on 5/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mi 7/2211:30 am
ORD
- STL
1 stop5h 54m
Delta
Mi 7/291:54 pm
STL
- ORD
1 stop6h 37m
Delta
Deal found 5/29![Delta logo]()
$258
This Southwest deal was found by Cheapflights users on 5/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Jo 8/206:20 am
DTW
- MCI
1 stop8h 20m
Southwest
Mi 8/266:30 am
MCI
- DTW
1 stop4h 50m
Southwest
Deal found 5/29![Southwest logo]()
$299
This United Airlines deal was found by Cheapflights users on 5/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Jo 7/3010:00 pm
ORD
- COU
Nonstop1h 33m
United Airlines
Vi 8/78:00 am
COU
- ORD
Nonstop1h 40m
United Airlines
Deal found 5/25![United Airlines logo]()
$309
This Delta deal was found by Cheapflights users on 5/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sâ 9/127:10 am
ORD
- STL
2 stops10h 52m
Delta
Lu 9/141:55 pm
STL
- ORD
1 stop4h 31m
Delta
Deal found 5/24![Delta logo]()
$262
Last-minute flights from Michigan to MissouriDiscover last-minute flight deals from Michigan to Missouri. Data last updated mai 30, 2026 and is based on user searches.
Discover last-minute flight deals from Michigan to Missouri. Data last updated mai 30, 2026 and is based on user searches.
This United Airlines deal was found by Cheapflights users on 5/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Ma 6/167:05 am
DTW
- STL
1 stop6h 06m
United Airlines
Sâ 6/207:05 pm
STL
- DTW
1 stop3h 52m
United Airlines
Deal found 5/25![United Airlines logo]()
$172
This Southwest deal was found by Cheapflights users on 5/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Ma 6/167:05 am
DTW
- STL
Nonstop1h 35m
Southwest
Sâ 6/204:40 pm
STL
- DTW
1 stop4h 45m
Southwest
Deal found 5/25![Southwest logo]()
$193
This Frontier deal was found by Cheapflights users on 5/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Ma 6/166:30 am
DTW
- STL
1 stop12h 00m
Frontier
Mi 6/175:06 pm
STL
- DTW
1 stop6h 38m
Frontier
Deal found 5/25![Frontier logo]()
$230
This United Airlines deal was found by Cheapflights users on 5/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Jo 6/187:05 am
DTW
- STL
1 stop6h 06m
United Airlines
Du 6/215:29 pm
STL
- DTW
1 stop3h 50m
United Airlines
Deal found 5/28![United Airlines logo]()
$205
This Delta deal was found by Cheapflights users on 5/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Vi 6/198:50 am
DTW
- STL
Nonstop1h 42m
Delta
Du 6/216:30 am
STL
- DTW
Nonstop1h 34m
Delta
Deal found 5/28![Delta logo]()
$177
This United Airlines deal was found by Cheapflights users on 5/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Du 6/218:50 am
DTW
- STL
1 stop4h 21m
United Airlines
Du 6/215:29 pm
STL
- DTW
1 stop3h 50m
United Airlines
Deal found 5/26![United Airlines logo]()
$209
This American Airlines deal was found by Cheapflights users on 5/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Lu 6/228:15 am
ORD
- SGF
Nonstop1h 49m
American Airlines
Lu 6/292:21 pm
SGF
- ORD
Nonstop1h 52m
American Airlines
Deal found 5/25![American Airlines logo]()
$248
This United Airlines deal was found by Cheapflights users on 5/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Ma 6/237:05 am
DTW
- STL
1 stop6h 06m
United Airlines
Ma 6/235:29 pm
STL
- DTW
1 stop5h 28m
United Airlines
Deal found 5/27![United Airlines logo]()
$198
This Delta deal was found by Cheapflights users on 5/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Ma 6/238:00 pm
DTW
- STL
Nonstop1h 39m
Delta
Jo 7/96:30 am
STL
- DTW
Nonstop1h 34m
Delta
Deal found 5/28![Delta logo]()
$228
This United Airlines deal was found by Cheapflights users on 5/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mi 6/2411:00 am
DTW
- STL
1 stop5h 46m
United Airlines
Mi 7/15:33 pm
STL
- DTW
1 stop3h 46m
United Airlines
Deal found 5/27![United Airlines logo]()
$203
This Southwest deal was found by Cheapflights users on 5/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mi 6/247:05 am
DTW
- STL
Nonstop1h 35m
Southwest
Mi 7/13:10 pm
STL
- DTW
1 stop6h 15m
Southwest
Deal found 5/27![Southwest logo]()
$219
This American Airlines deal was found by Cheapflights users on 5/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mi 6/244:44 pm
ORD
- COU
Nonstop1h 33m
American Airlines
Du 6/286:00 am
COU
- ORD
Nonstop1h 38m
American Airlines
Deal found 5/27![American Airlines logo]()
$239
One-way flights from Michigan to MissouriSearch for one-way flight options from Michigan to Missouri. Find affordable one-way fares based on user searches. Data last updated mai 30, 2026.
Search for one-way flight options from Michigan to Missouri. Find affordable one-way fares based on user searches. Data last updated mai 30, 2026.
This Southwest deal was found by Cheapflights users on 5/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mi 7/159:10 pm
MDW
- STL
Nonstop1h 20m
Southwest
Deal found 5/28![Southwest logo]()
$69
This American Airlines deal was found by Cheapflights users on 5/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mi 7/2911:00 pm
ORD
- STL
Nonstop1h 16m
American Airlines
Deal found 5/29![American Airlines logo]()
$69
This American Airlines deal was found by Cheapflights users on 5/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Ma 6/1611:00 pm
ORD
- STL
Nonstop1h 16m
American Airlines
Deal found 5/25![American Airlines logo]()
$70
This Southwest deal was found by Cheapflights users on 5/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Ma 7/147:05 am
DTW
- STL
Nonstop1h 35m
Southwest
Deal found 5/27![Southwest logo]()
$79
This Delta deal was found by Cheapflights users on 5/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mi 7/221:18 pm
MDW
- STL
1 stop4h 06m
Delta
Deal found 5/28![Delta logo]()
$79
This Delta deal was found by Cheapflights users on 5/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mi 7/157:05 am
ORD
- STL
1 stop6h 00m
Delta
Deal found 5/29![Delta logo]()
$79
This Southwest deal was found by Cheapflights users on 5/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Ma 8/252:45 pm
DTW
- STL
1 stop7h 25m
Southwest
Deal found 5/28![Southwest logo]()
$82
This United Airlines deal was found by Cheapflights users on 5/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mi 6/177:05 am
DTW
- STL
1 stop6h 06m
United Airlines
Deal found 5/27![United Airlines logo]()
$84
This United Airlines deal was found by Cheapflights users on 5/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mi 7/811:00 am
DTW
- STL
1 stop5h 46m
United Airlines
Deal found 5/27![United Airlines logo]()
$89
This Southwest deal was found by Cheapflights users on 5/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sâ 7/410:30 am
DTW
- STL
2 stops9h 50m
Southwest
Deal found 5/27![Southwest logo]()
$94
This Southwest deal was found by Cheapflights users on 5/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sâ 9/56:35 am
DTW
- STL
Nonstop1h 35m
Southwest
Deal found 5/28![Southwest logo]()
$96
This Southwest deal was found by Cheapflights users on 5/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sâ 8/226:15 pm
MDW
- STL
Nonstop1h 15m
Southwest
Deal found 5/26![Southwest logo]()
$96
Find flight deals from Michigan to Missouri
Keep the following information in mind while searching for Michigan to Missouri flight deals. Data was last updated mai 30, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $172 (United Airlines) |
One-way from | $69 (Southwest) |
Popular in | April |
Cheapest in | August |
Average price | $327 |
Good round-trip deal | $361 or less |
Good one-way deal | $234 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Michigan to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated mai 30, 2026.
Use the filters below to find and compare flights from Michigan to Missouri that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
DetroitSt. Louis
DTW - STL
DTWSTL
Detroit Metropolitan Wayne County
Jo 7/9
8:50 am-9:31 am
Nonstop1h 41m
Lambert-St Louis
Lu 7/13
6:09 pm-8:44 pm
Nonstop1h 35m
$177
DetroitSt. Louis
DTW - STL
DTWSTL
Detroit Metropolitan Wayne County
Mi 6/24
4:41 pm-5:23 pm
Nonstop1h 42m
Lambert-St Louis
Du 6/28
6:30 am-9:04 am
Nonstop1h 34m
$177
DetroitSt. Louis
DTW - STL
DTWSTL
Detroit Metropolitan Wayne County
Vi 7/17
8:50 am-9:31 am
Nonstop1h 41m
Lambert-St Louis
Du 7/19
6:30 am-9:04 am
Nonstop1h 34m
$177
DetroitSt. Louis
DTW - STL
DTWSTL
Detroit Metropolitan Wayne County
Jo 7/16
8:50 am-9:31 am
Nonstop1h 41m
Lambert-St Louis
Lu 7/20
6:09 pm-8:44 pm
Nonstop1h 35m
$177
DetroitSt. Louis
DTW - STL
DTWSTL
Detroit Metropolitan Wayne County
Sâ 8/1
8:50 am-9:31 am
Nonstop1h 41m
Lambert-St Louis
Lu 8/3
6:30 am-9:04 am
Nonstop1h 34m
$177
DetroitSt. Louis
DTW - STL
DTWSTL
Detroit Metropolitan Wayne County
Jo 7/23
8:50 am-9:31 am
Nonstop1h 41m
Lambert-St Louis
Vi 7/31
6:30 am-9:04 am
Nonstop1h 34m
$177
DetroitSt. Louis
DTW - STL
DTWSTL
Detroit Metropolitan Wayne County
Ma 8/25
12:55 pm-8:00 pm
2 stops8h 05m
Lambert-St Louis
Ma 9/1
4:45 pm-9:30 pm
1 stop3h 45m
$208
DetroitSt. Louis
DTW - STL
DTWSTL
Detroit Metropolitan Wayne County
Mi 7/22
7:05 am-7:40 am
Nonstop1h 35m
Lambert-St Louis
Mi 7/22
7:40 pm-10:15 pm
Nonstop1h 35m
$209
DetroitSt. Louis
DTW - STL
DTWSTL
Detroit Metropolitan Wayne County
Sâ 8/22
9:00 am-9:37 am
Nonstop1h 37m
Lambert-St Louis
Sâ 8/29
5:42 pm-10:41 pm
1 stop3h 59m
$218
ChicagoColumbia
ORD - COU
ORDCOU
Chicago O'Hare Intl
Jo 7/9
8:40 am-10:13 am
Nonstop1h 33m
Columbia Regional
Du 7/12
8:00 am-9:40 am
Nonstop1h 40m
$239
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from Michigan to Missouri
Have a flexible travel schedule? Discover the best time to fly to Missouri from Michigan with our price prediction graph.
DTW-STL
ORD-COU
GRR-STL
MDW-STL
ORD-STL
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Michigan to Missouri
USMI-USMO
DTW-STL
ORD-COU
GRR-STL
MDW-STL
What is the cheapest month to book a flight from Michigan to Missouri?
Currently, August is the cheapest month in which you can book a flight from Michigan to Missouri (average of $27). Flying from Michigan to Missouri in January is currently the most expensive (average of $145). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from MI to MO?
Find hourly flight availability from Michigan to Missouri. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated mai 30, 2026.
It’s typically best to fly out from Michigan to Missouri at noon. Doing so could potentially save you 22% on the flight price compared to flying in the afternoon, which is usually more expensive.
Weekly flight availability from Michigan to Missouri
Explore weekly flight availability from Michigan to Missouri. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated mai 30, 2026.
The most flights from USMI to USMO are scheduled on a Tuesday (15 on average). You will have fewer flight options on Saturday, which is when the least amount of flights are scheduled (9 on average).
How much does it cost to fly round-trip from Michigan to Missouri?
How far ahead should I book a flight from Michigan to Missouri?
Booking 39 days in advance of your planned departure date is, on average, the best time to get cheap flights from Michigan to Missouri. The general trend is that the closer you book to the departure date, the more expensive your flight will be.
What is the cheapest day to fly from Michigan to Missouri?
Use this chart to determine the cheapest time to fly round-trip from Michigan to Missouri. Price data was last updated on May 23, 2026.
Travelers seeking maximum savings on their Michigan to Missouri flight should consider departing on Sunday at noon when fares are most often at their lowest. Monday evenings flights should be avoided if possible as fares are typically the most expensive at this time.
Reviews of airlines servicing Missouri
Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated mai 30, 2026.
Peruse reviews from past customers who have flown with Southwest,Delta, andUnited Airlines from Michigan to Missouri to help guide your decision. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
7.5
Boarding
8.1
Comfort
8.0
Crew
8.6
Overall
8.0
Food
7.0
Reviews
1 / 20
10.0
ExcellentWalter,May 2026
LAS - BUR
Entertainment
7.5
Boarding
8.1
Comfort
8.0
Crew
8.6
Overall
8.0
Food
7.0
Reviews
1 / 20
10.0
ExcellentWalter,May 2026
LAS - BUR
Entertainment
7.5
Boarding
8.1
Comfort
8.0
Crew
8.6
Overall
8.0
Food
7.0
Reviews
1 / 20
10.0
ExcellentWalter,May 2026
LAS - BUR
Entertainment
7.5
Boarding
8.1
Comfort
8.0
Crew
8.6
Overall
8.0
Food
7.0
Reviews
1 / 20
10.0
ExcellentWalter,May 2026
LAS - BUR
Entertainment
7.5
Boarding
8.1
Comfort
8.0
Crew
8.6
Overall
8.0
Food
7.0
Reviews
1 / 20
10.0
ExcellentWalter,May 2026
LAS - BUR
Spirit Airlines
Entertainment
7.5
Boarding
8.1
Comfort
8.0
Crew
8.6
Overall
8.0
Food
7.0
Reviews
1 / 20
10.0
ExcellentWalter,May 2026
LAS - BUR
Related info for your journey
Find useful and relevant information for your journey from Michigan to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
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Alternative routes for Michigan to Missouri
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Missouri by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Michigan to Missouri by cabin class
Find flights from Michigan to Missouri, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Michigan and Missouri flights
Browse other Michigan and Missouri flight options. Last updated on mai 30, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Find a return flight route from Missouri
Find the right flight back to Michigan after your stay in Missouri
Michigan to Missouri flights
Consider these flights traveling from Michigan to Missouri.
Top 6 airlines flying from Michigan to Missouri
Discover the top 6 airlines that operate flights from Michigan to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated mai 30, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$28 | Average$149 | FlexibilityNo cancel fee | On-time65% | |
| Cheapest$111 | Average$227 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$120 | Average$373 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$149 | Average$385 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$199 | Average$362 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$228 | Average$390 | FlexibilityNo cancel fee | On-time69% |