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$80+ Cheap flights from Jacksonville (JAX) to Missouri

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/24. Fares are subject to change and may not be available on all flights or dates of travel.
JAX — STL
Nov 28 — Dec 51
Fri 11/28
Fri 12/5
1 adult, Economy
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Cheap flight deals from Jacksonville to Missouri

Keep the following information in mind while searching for Jacksonville to Missouri flight deals. Data was last updated October 29, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$237
(Southwest)

One-way from

$80
(Trip.com)

Popular in

March

Cheapest in

July

Average price

$423

Good round-trip deal

$338 or less

Good one-way deal

$173 or less
Provider with most accurate pricing for Jacksonville-Lambert-St Louis flight deals.
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Provider most trusted by Cheapflights users for Jacksonville-Lambert-St Louis flights.
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From Jacksonville to Missouri
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One-way flight from Jacksonville to Missouri
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Highest demand for flights based on searches. 5% potential increase in price ($18 potential increase over avg. RT price).
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Cheapest flight prices on average. 2% potential price decrease ($10 potential savings vs. average RT price).
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Average for round-trip flights in October 2025
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Price to beat on a round-trip flight from Jacksonville to Missouri.
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Price to beat on a one-way flight from Jacksonville to Missouri.
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Find flight deals from Jacksonville to Missouri

Cheapest flights from Jacksonville to Missouri
Explore the most affordable flight options available from Jacksonville to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 29, 2025.

This Southwest deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/178:15 amJAX - STL
Nonstop2h 20mSouthwest
Thu 12/187:50 amSTL - JAX
Nonstop2h 00mSouthwest
Deal found 10/27$237
This Delta deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/318:05 amJAX - STL
1 stop5h 16mDelta
Thu 1/17:00 amSTL - JAX
1 stop4h 38mDelta
Deal found 10/28$247
This United Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/58:10 amJAX - SGF
1 stop7h 34mUnited Airlines
Sun 12/73:21 pmSGF - JAX
1 stop5h 11mUnited Airlines
Deal found 10/29$249
This American Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/1112:55 pmJAX - SGF
1 stop5h 09mAmerican Airlines
Sat 11/1510:21 amSGF - JAX
1 stop5h 54mAmerican Airlines
Deal found 10/27$259
This United Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/1110:00 amJAX - SGF
2 stops13h 13mUnited Airlines
Sat 11/159:00 amSGF - JAX
1 stop7h 51mUnited Airlines
Deal found 10/27$264
This Southwest deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/176:10 pmJAX - STL
Nonstop2h 20mSouthwest
Thu 12/258:25 amSTL - JAX
1 stop5h 55mSouthwest
Deal found 10/29$264
This Southwest deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/248:15 amJAX - STL
Nonstop2h 20mSouthwest
Mon 12/299:00 pmSTL - JAX
Nonstop1h 55mSouthwest
Deal found 10/27$277
This Delta deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/99:45 amJAX - STL
1 stop4h 19mDelta
Fri 12/127:02 pmSTL - JAX
1 stop4h 09mDelta
Deal found 10/27$282
This Southwest deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/411:50 amJAX - STL
1 stop5h 00mSouthwest
Sun 12/78:50 pmSTL - JAX
Nonstop1h 55mSouthwest
Deal found 10/27$283
This American Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/63:39 pmJAX - SGF
1 stop7h 31mAmerican Airlines
Mon 11/104:07 pmSGF - JAX
1 stop5h 27mAmerican Airlines
Deal found 10/27$289
This Delta deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/115:05 amJAX - SGF
1 stop6h 45mDelta
Sun 12/146:53 pmSGF - JAX
1 stop4h 18mDelta
Deal found 10/26$304
This Delta deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/48:20 amJAX - MCI
1 stop7h 01mDelta
Tue 12/910:24 amMCI - JAX
1 stop6h 11mDelta
Deal found 10/27$313

Cheapflights Fare Finder

 
Customize your flight search to find flights from Jacksonville to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 29, 2025.
Use the filters below to find and compare flights from Jacksonville to Missouri that are best for you.

Fly from

Jacksonville

Fly to

Missouri

Route

Depart

Return

Price

JacksonvilleSt. Louis

JAX - STL

JAXSTL

Jacksonville

Wed 12/31

7:00 am-12:21 pm

1 stop6h 21m

Lambert-St Louis

Thu 1/1

7:00 am-2:23 pm

1 stop6h 23m

$247

JacksonvilleSt. Louis

JAX - STL

JAXSTL

Jacksonville

Thu 2/19

3:45 pm-8:39 pm

1 stop5h 54m

Lambert-St Louis

Mon 2/23

10:00 am-5:28 pm

1 stop6h 28m

$247

JacksonvilleSpringfield

JAX - SGF

JAXSGF

Jacksonville

Fri 12/5

1:03 pm-5:05 pm

1 stop5h 02m

Springfield-Branson

Sun 12/7

6:34 pm-11:57 pm

1 stop4h 23m

$249

JacksonvilleSpringfield

JAX - SGF

JAXSGF

Jacksonville

Thu 12/11

6:49 am-1:31 pm

1 stop7h 42m

Springfield-Branson

Sun 12/14

4:23 pm-11:57 pm

1 stop6h 34m

$249

JacksonvilleSpringfield

JAX - SGF

JAXSGF

Jacksonville

Fri 12/5

11:47 am-3:23 pm

1 stop4h 36m

Springfield-Branson

Sun 12/7

6:53 pm-12:11 am

1 stop4h 18m

$249

JacksonvilleSpringfield

JAX - SGF

JAXSGF

Jacksonville

Tue 11/11

12:55 pm-5:04 pm

1 stop5h 09m

Springfield-Branson

Sat 11/15

10:21 am-5:15 pm

1 stop5h 54m

$259

JacksonvilleSt. Louis

JAX - STL

JAXSTL

Jacksonville

Wed 12/17

6:10 am-1:05 pm

2 stops7h 55m

Lambert-St Louis

Thu 12/18

6:40 am-2:20 pm

1 stop6h 40m

$262

JacksonvilleSpringfield

JAX - SGF

JAXSGF

Jacksonville

Tue 11/11

10:00 am-10:13 pm

2 stops13h 13m

Springfield-Branson

Sat 11/15

9:00 am-5:51 pm

1 stop7h 51m

$264

JacksonvilleSt. Louis

JAX - STL

JAXSTL

Jacksonville

Wed 12/17

6:10 pm-7:30 pm

Nonstop2h 20m

Lambert-St Louis

Thu 12/25

8:25 am-3:20 pm

1 stop5h 55m

$264

JacksonvilleSt. Louis

JAX - STL

JAXSTL

Jacksonville

Wed 12/24

8:15 am-9:35 am

Nonstop2h 20m

Lambert-St Louis

Mon 12/29

9:00 pm-11:55 pm

Nonstop1h 55m

$277

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/29

Showing 1-10 of 54 results
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Best time to book a flight from Jacksonville to Missouri

Have a flexible travel schedule? Discover the best time to fly to Missouri from Jacksonville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Jacksonville to Missouri

What is the cheapest month to book a flight from Jacksonville to Missouri?

Currently, April is the cheapest month in which you can book a flight from Jacksonville to Missouri (average of $139). Flying from Jacksonville to Missouri in December is currently the most expensive (average of $229). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from JAX to MO?

Find hourly flight availability from Jacksonville to Missouri. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated October 29, 2025.

It’s optimal to fly from Jacksonville to Missouri in the evening. By choosing this option you can save up to 37% on the cost of your flight, compared to a flight in the morning.

What is the cheapest day to fly from Jacksonville to Missouri?

Use this chart to determine the cheapest time to fly round-trip from Jacksonville to Missouri. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their Jacksonville to Missouri flight should consider departing on Tuesday afternoons when fares are most often at their lowest. Sunday at noon flights should be avoided if possible as fares are typically the most expensive at this time.

How much does it cost to fly round-trip from Jacksonville to Missouri?

Reviews of airlines servicing Missouri

Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated October 29, 2025.
Peruse reviews from past customers who have flown with Southwest, Delta, and American Airlines from Jacksonville to Missouri to help guide your decision. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,241 reviews

Entertainment

7.5

Comfort

8.0

Boarding

8.1

Overall

8.0

Crew

8.6

Food

7.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Southwest
8.0
Very good
4,241 reviews
Southwest
8.0
Very good
4,241 reviews

Entertainment

7.5

Comfort

8.0

Boarding

8.1

Overall

8.0

Crew

8.6

Food

7.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Delta
7.9
Good
7,992 reviews
Southwest
8.0
Very good
4,241 reviews

Entertainment

7.5

Comfort

8.0

Boarding

8.1

Overall

8.0

Crew

8.6

Food

7.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
American Airlines
7.2
Good
11,032 reviews
Southwest
8.0
Very good
4,241 reviews

Entertainment

7.5

Comfort

8.0

Boarding

8.1

Overall

8.0

Crew

8.6

Food

7.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines

Related info for your journey

Find useful and relevant information for your journey from Jacksonville to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Jacksonville to Missouri?

    Located just 11.2 mi from the city center, Jacksonville (JAX) is the airport most travelers will use when flying to Missouri from Jacksonville.

  • How popular is this Jacksonville to Missouri flight route?

    Within the past month, 22 users have taken a look at flights from Jacksonville to Missouri.

  • How long is the flight from Jacksonville to Missouri?

    For as low as $249, Delta can have you in Missouri from Jacksonville in 5h 02m. There are 816 mi between Jacksonville and Missouri. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines to fly from Jacksonville to Missouri one-way?

    For one-way options, check prices for Southwest. According to our data, you can fly for as low as $119. Users have also found prices from $124 and $131 on Delta and United Airlines, respectively.

  • What are the most popular routes from Jacksonville to Missouri?

    When deciding which route to take from Jacksonville to Missouri consider Jacksonville - Kansas City, Jacksonville - Lambert-St Louis or Jacksonville - Springfield-Branson as they are the most popular.

  • What are the cheapest flights from Jacksonville to Missouri?

    The cheapest flight price from Jacksonville to Missouri is $125. On average you can expect to pay $309. The most popular route, (Jacksonville - Kansas City), can usually be booked for $313.

  • Can I find deals for flights from Jacksonville to Missouri that include hotel bookings?

    Yes. In addition to deals on Jacksonville to Missouri flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Jacksonville to Missouri?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Jacksonville to Missouri.

  • Can I find deals for business class flights from Jacksonville to Missouri?

    Yes. Cheapflights offers flight deals from Jacksonville to Missouri by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Jacksonville to Missouri?

    Currently, April is the cheapest month in which you can book a flight from Jacksonville to Missouri (average of $139). Flying from Jacksonville to Missouri in December is currently the most expensive (average of $229). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Jacksonville to Missouri

See prices for flight routes from nearby airports that may be better suited for you.
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Top 3 airlines flying from Jacksonville to Missouri

Discover the top 3 airlines that operate flights from Jacksonville to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 29, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$194Average$336FlexibilityNo cancel feeOn-timeN/A
SouthwestCheapest$214Average$339FlexibilityNo cancel feeOn-time63%
American AirlinesCheapest$218Average$395FlexibilityNo cancel feeOn-time71%

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