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$65+ Cheap flights from Jacksonville (JAX) to Missouri

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/16. Fares are subject to change and may not be available on all flights or dates of travel.
JAX — STL
Oct 15 — Oct 221
Wed 10/15
Wed 10/22
1 adult, Economy
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Cheap flight deals from Jacksonville to Missouri

Keep the following information in mind while searching for Jacksonville to Missouri flight deals. Data was last updated September 15, 2025.

Round-trip from

$183
(Delta)

One-way from

$65
(Trip.com)

Popular in

May

Cheapest in

January

Average price

$330

Good round-trip deal

$270 or less

Good one-way deal

$168 or less
From Jacksonville to Missouri
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One-way flight from Jacksonville to Missouri
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Highest demand for flights based on searches. 7% potential increase in price ($30 potential increase over avg. RT price).
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Cheapest flight prices on average. 2% potential price decrease ($11 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Price to beat on a round-trip flight from Jacksonville to Missouri.
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Price to beat on a one-way flight from Jacksonville to Missouri.
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Find flight deals from Jacksonville to Missouri

Cheapest flights from Jacksonville to Missouri
Explore the most affordable flight options available from Jacksonville to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 15, 2025.

This Delta deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/303:10 pmJAX - STL
1 stop5h 55mDelta
Tue 10/711:21 amSTL - JAX
1 stop4h 06mDelta
Deal found 9/11$183
This American Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/303:06 pmJAX - STL
2 stops6h 26mAmerican Airlines
Tue 10/78:30 amSTL - JAX
1 stop5h 39mAmerican Airlines
Deal found 9/11$188
This Delta deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/238:11 pmJAX - STL
1 stop4h 30mDelta
Thu 10/306:00 amSTL - JAX
1 stop5h 40mDelta
Deal found 9/11$193
This Southwest deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/308:15 amJAX - STL
Nonstop2h 10mSouthwest
Tue 10/78:15 amSTL - JAX
Nonstop1h 55mSouthwest
Deal found 9/11$194
This Delta deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/117:10 pmJAX - MCI
1 stop5h 42mDelta
Sat 10/183:55 pmMCI - JAX
1 stop4h 03mDelta
Deal found 9/13$209
This American Airlines deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/206:54 amJAX - STL
1 stop7h 49mAmerican Airlines
Sun 11/234:46 pmSTL - JAX
1 stop4h 43mAmerican Airlines
Deal found 9/12$213
This Southwest deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/237:55 amJAX - STL
Nonstop2h 10mSouthwest
Thu 10/308:15 pmSTL - JAX
Nonstop1h 55mSouthwest
Deal found 9/11$224
This Southwest deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/65:40 amJAX - STL
1 stop5h 10mSouthwest
Mon 10/68:15 pmSTL - JAX
Nonstop1h 55mSouthwest
Deal found 9/12$234
This Southwest deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/138:15 pmJAX - STL
Nonstop2h 10mSouthwest
Mon 10/208:15 pmSTL - JAX
Nonstop1h 55mSouthwest
Deal found 9/13$237
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/267:22 amJAX - STL
1 stop7h 22mAmerican Airlines
Wed 10/2912:51 pmSTL - JAX
1 stop5h 13mAmerican Airlines
Deal found 9/14$238
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/65:01 amJAX - SGF
1 stop6h 34mAmerican Airlines
Mon 11/105:35 pmSGF - JAX
1 stop4h 24mAmerican Airlines
Deal found 9/14$249
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/18:21 amJAX - SGF
1 stop4h 46mAmerican Airlines
Tue 10/75:28 pmSGF - JAX
1 stop4h 43mAmerican Airlines
Deal found 9/14$254

Cheapflights Fare Finder

 
Customize your flight search to find flights from Jacksonville to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 15, 2025.
Use the filters below to find and compare flights from Jacksonville to Missouri that are best for you.

Fly from

Jacksonville

Fly to

Missouri

Route

Depart

Return

Price

JacksonvilleSt. Louis

JAX - STL

JAXSTL

Jacksonville

Tue 9/30

3:10 pm-8:05 pm

1 stop5h 55m

Lambert-St Louis

Tue 10/7

11:21 am-4:27 pm

1 stop4h 06m

$183

JacksonvilleSt. Louis

JAX - STL

JAXSTL

Jacksonville

Thu 10/23

8:11 pm-11:41 pm

1 stop4h 30m

Lambert-St Louis

Thu 10/30

6:00 am-12:40 pm

1 stop5h 40m

$193

JacksonvilleSt. Louis

JAX - STL

JAXSTL

Jacksonville

Thu 2/19

5:30 am-10:50 am

1 stop6h 20m

Lambert-St Louis

Mon 2/23

9:00 am-4:49 pm

1 stop6h 49m

$193

JacksonvilleSt. Louis

JAX - STL

JAXSTL

Jacksonville

Tue 9/30

8:15 am-9:25 am

Nonstop2h 10m

Lambert-St Louis

Tue 10/7

8:15 am-11:10 am

Nonstop1h 55m

$194

JacksonvilleSt. Louis

JAX - STL

JAXSTL

Jacksonville

Thu 2/19

3:50 pm-11:58 pm

1 stop9h 08m

Lambert-St Louis

Mon 2/23

7:00 am-2:33 pm

1 stop6h 33m

$221

JacksonvilleSt. Louis

JAX - STL

JAXSTL

Jacksonville

Thu 12/18

7:10 pm-8:30 pm

Nonstop2h 20m

Lambert-St Louis

Wed 12/24

6:10 pm-9:05 pm

Nonstop1h 55m

$237

JacksonvilleSt. Louis

JAX - STL

JAXSTL

Jacksonville

Mon 10/13

8:15 pm-9:25 pm

Nonstop2h 10m

Lambert-St Louis

Mon 10/20

8:15 pm-11:10 pm

Nonstop1h 55m

$237

JacksonvilleSt. Louis

JAX - STL

JAXSTL

Jacksonville

Mon 11/17

8:15 am-9:35 am

Nonstop2h 20m

Lambert-St Louis

Mon 11/24

5:10 am-12:20 pm

1 stop6h 10m

$237

JacksonvilleSpringfield

JAX - SGF

JAXSGF

Jacksonville

Wed 2/18

6:46 pm-9:41 pm

1 stop3h 55m

Springfield-Branson

Sat 2/21

1:00 pm-8:38 pm

1 stop6h 38m

$241

JacksonvilleSpringfield

JAX - SGF

JAXSGF

Jacksonville

Thu 11/13

6:03 pm-10:10 pm

1 stop5h 07m

Springfield-Branson

Mon 11/17

5:35 pm-10:59 pm

1 stop4h 24m

$249

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/13

Showing 1-10 of 53 results
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Best time to book a flight from Jacksonville to Missouri

Have a flexible travel schedule? Discover the best time to fly to Missouri from Jacksonville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Jacksonville to Missouri

What is the cheapest month to book a flight from Jacksonville to Missouri?

Currently, August is the cheapest month in which you can book a flight from Jacksonville to Missouri (average of $311). Flying from Jacksonville to Missouri in March is currently the most expensive (average of $356). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from JAX to MO?

Find hourly flight availability from Jacksonville to Missouri. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 15, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Jacksonville to Missouri as you normally would.

Reviews of airlines servicing Missouri

Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated September 15, 2025.
Peruse reviews from past customers who have flown with Southwest, Delta, and United Airlines from Jacksonville to Missouri to help guide your decision. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,245 reviews

Boarding

8.1

Entertainment

7.5

Overall

8.0

Food

7.0

Comfort

8.0

Crew

8.6

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Southwest
8.0
Very good
4,245 reviews
Southwest
8.0
Very good
4,245 reviews

Boarding

8.1

Entertainment

7.5

Overall

8.0

Food

7.0

Comfort

8.0

Crew

8.6

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Delta
8.0
Very good
7,956 reviews
Southwest
8.0
Very good
4,245 reviews

Boarding

8.1

Entertainment

7.5

Overall

8.0

Food

7.0

Comfort

8.0

Crew

8.6

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
United Airlines
7.4
Good
8,931 reviews
Southwest
8.0
Very good
4,245 reviews

Boarding

8.1

Entertainment

7.5

Overall

8.0

Food

7.0

Comfort

8.0

Crew

8.6

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
American Airlines
7.2
Good
10,000 reviews
Southwest
8.0
Very good
4,245 reviews

Boarding

8.1

Entertainment

7.5

Overall

8.0

Food

7.0

Comfort

8.0

Crew

8.6

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines

Related info for your journey

Find useful and relevant information for your journey from Jacksonville to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Jacksonville to Missouri?

    Located just 11.2 mi from the city center, Jacksonville (JAX) is the airport most travelers will use when flying to Missouri from Jacksonville.

  • How popular is this Jacksonville to Missouri flight route?

    Within the past month, 20 users have taken a look at flights from Jacksonville to Missouri.

  • How long is the flight from Jacksonville to Missouri?

    For as low as $194, Delta can have you in Missouri from Jacksonville in 2h 10m. There are 753 mi between Jacksonville and Missouri. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the most popular routes from Jacksonville to Missouri?

    When deciding which route to take from Jacksonville to Missouri consider Jacksonville - Lambert-St Louis, Jacksonville - Kansas City or Jacksonville - Springfield-Branson as they are the most popular.

  • What are the cheapest flights from Jacksonville to Missouri?

    The cheapest flight price from Jacksonville to Missouri is $104. On average you can expect to pay $261. The most popular route, (Jacksonville - Lambert-St Louis), can usually be booked for $151.

  • Can I find deals for flights from Jacksonville to Missouri that include hotel bookings?

    Yes. In addition to deals on Jacksonville to Missouri flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Jacksonville to Missouri?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Jacksonville to Missouri.

  • Can I find deals for business class flights from Jacksonville to Missouri?

    Yes. Cheapflights offers flight deals from Jacksonville to Missouri by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Jacksonville to Missouri?

    Currently, August is the cheapest month in which you can book a flight from Jacksonville to Missouri (average of $311). Flying from Jacksonville to Missouri in March is currently the most expensive (average of $356). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Jacksonville to Missouri

See prices for flight routes from nearby airports that may be better suited for you.
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Top 3 airlines flying from Jacksonville to Missouri

Discover the top 3 airlines that operate flights from Jacksonville to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 15, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$199Average$351FlexibilityNo cancel feeOn-timeN/A
SouthwestCheapest$216Average$345FlexibilityNo cancel feeOn-time63%
American AirlinesCheapest$218Average$397FlexibilityNo cancel feeOn-time71%

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