$130+ Cheap flights from Jacksonville (JAX) to Missouri
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/12. Fares are subject to change and may not be available on all flights or dates of travel.
JAX — STL
Apr 16 — Apr 231
Round-trip
1 adult, Economy
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Find cheap flights from Jacksonville to Missouri with Cheapflights
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Cheapest flights from Jacksonville to MissouriExplore the most affordable flight options available from Jacksonville to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 17, 2026.
Explore the most affordable flight options available from Jacksonville to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 17, 2026.
This American Airlines deal was found by Cheapflights users on 3/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/256:00 am
JAX
- SGF
1 stop6h 04m
American Airlines
Sat 5/212:00 pm
SGF
- JAX
1 stop8h 02m
American Airlines
Deal found 3/14![American Airlines logo]()
$281
This Southwest deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/298:20 am
JAX
- STL
Nonstop2h 15m
Southwest
Sat 5/28:45 am
STL
- JAX
Nonstop2h 00m
Southwest
Deal found 3/16![Southwest logo]()
$283
This Southwest deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/148:20 am
JAX
- STL
Nonstop2h 15m
Southwest
Wed 4/1510:15 am
STL
- JAX
Nonstop2h 00m
Southwest
Deal found 3/16![Southwest logo]()
$291
This American Airlines deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/87:48 pm
JAX
- SGF
1 stop5h 08m
American Airlines
Sat 5/165:47 pm
SGF
- JAX
1 stop4h 57m
American Airlines
Deal found 3/13![American Airlines logo]()
$295
This American Airlines deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/72:35 pm
JAX
- STL
1 stop5h 55m
American Airlines
Fri 4/176:55 pm
STL
- JAX
1 stop4h 26m
American Airlines
Deal found 3/12![American Airlines logo]()
$297
This Delta deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/115:30 am
JAX
- STL
1 stop4h 32m
Delta
Tue 4/147:25 am
STL
- JAX
1 stop3h 44m
Delta
Deal found 3/12![Delta logo]()
$299
This Delta deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/16:46 pm
JAX
- SGF
1 stop4h 49m
Delta
Sat 8/86:00 am
SGF
- JAX
1 stop6h 37m
Delta
Deal found 3/13![Delta logo]()
$301
This Southwest deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/103:35 pm
JAX
- STL
Nonstop2h 15m
Southwest
Mon 4/131:55 pm
STL
- JAX
Nonstop2h 00m
Southwest
Deal found 3/12![Southwest logo]()
$304
This Delta deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/36:05 am
JAX
- STL
1 stop4h 39m
Delta
Sun 6/77:05 pm
STL
- JAX
1 stop5h 03m
Delta
Deal found 3/12![Delta logo]()
$307
This American Airlines deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/96:12 pm
JAX
- SGF
1 stop4h 42m
American Airlines
Mon 4/136:24 pm
SGF
- JAX
1 stop4h 57m
American Airlines
Deal found 3/12![American Airlines logo]()
$309
This Delta deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/148:18 pm
JAX
- STL
1 stop4h 41m
Delta
Tue 5/198:53 am
STL
- JAX
1 stop6h 42m
Delta
Deal found 3/16![Delta logo]()
$311
This Delta deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/22:30 pm
JAX
- SGF
1 stop4h 40m
Delta
Sat 8/84:00 pm
SGF
- JAX
1 stop4h 39m
Delta
Deal found 3/12![Delta logo]()
$315
Best flights from Jacksonville to MissouriDiscover carefully curated flight deals from Jacksonville to Missouri that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 17, 2026.
Discover carefully curated flight deals from Jacksonville to Missouri that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 17, 2026.
This Southwest deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/148:20 am
JAX
- STL
Nonstop2h 15m
Southwest
Wed 4/1510:15 am
STL
- JAX
Nonstop2h 00m
Southwest
Deal found 3/16![Southwest logo]()
$291
This Delta deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/22:30 pm
JAX
- SGF
1 stop4h 40m
Delta
Sat 8/86:00 am
SGF
- JAX
1 stop6h 37m
Delta
Deal found 3/12![Delta logo]()
$295
This United Airlines deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/15:25 pm
JAX
- STL
1 stop6h 05m
United Airlines
Sun 5/37:45 am
STL
- JAX
1 stop5h 53m
United Airlines
Deal found 3/12![United Airlines logo]()
$325
This American Airlines deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/75:45 am
JAX
- STL
1 stop7h 02m
American Airlines
Fri 4/176:55 pm
STL
- JAX
1 stop4h 26m
American Airlines
Deal found 3/16![American Airlines logo]()
$328
This Southwest deal was found by Cheapflights users on 3/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/137:10 pm
JAX
- STL
1 stop3h 50m
Southwest
Sun 5/175:35 pm
STL
- JAX
1 stop4h 40m
Southwest
Deal found 3/15![Southwest logo]()
$318
This Delta deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/125:30 am
JAX
- STL
1 stop3h 37m
Delta
Sun 6/217:05 pm
STL
- JAX
1 stop5h 03m
Delta
Deal found 3/12![Delta logo]()
$325
This United Airlines deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/55:00 pm
JAX
- STL
1 stop6h 56m
United Airlines
Wed 5/69:21 am
STL
- JAX
2 stops9h 41m
United Airlines
Deal found 3/11![United Airlines logo]()
$344
This Southwest deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/42:15 pm
JAX
- STL
2 stops7h 35m
Southwest
Sun 6/75:30 pm
STL
- JAX
Nonstop2h 00m
Southwest
Deal found 3/12![Southwest logo]()
$339
This Delta deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/62:30 pm
JAX
- SGF
1 stop4h 40m
Delta
Sun 8/96:45 pm
SGF
- JAX
1 stop5h 23m
Delta
Deal found 3/12![Delta logo]()
$351
This Southwest deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/13:25 pm
JAX
- STL
2 stops8h 15m
Southwest
Sun 5/39:55 pm
STL
- JAX
2 stops14h 55m
Southwest
Deal found 3/12![Southwest logo]()
$341
This United Airlines deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/298:00 am
JAX
- JLN
1 stop6h 12m
United Airlines
Sat 5/29:06 am
JLN
- JAX
2 stops12h 39m
United Airlines
Deal found 3/12![United Airlines logo]()
$384
This Southwest deal was found by Cheapflights users on 3/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/246:10 pm
JAX
- STL
Nonstop2h 20m
Southwest
Mon 5/254:40 pm
STL
- JAX
1 stop4h 25m
Southwest
Deal found 3/15![Southwest logo]()
$341
This United Airlines deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/146:35 am
JAX
- MCI
1 stop8h 26m
United Airlines
Tue 5/1911:29 am
MCI
- JAX
1 stop7h 10m
United Airlines
Deal found 3/12![United Airlines logo]()
$402
This Delta deal was found by Cheapflights users on 3/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/192:30 pm
JAX
- SGF
1 stop4h 40m
Delta
Mon 6/226:45 pm
SGF
- JAX
1 stop4h 17m
Delta
Deal found 3/15![Delta logo]()
$414
This Southwest deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/1112:55 pm
JAX
- MCI
1 stop7h 20m
Southwest
Tue 4/146:05 am
MCI
- JAX
1 stop6h 35m
Southwest
Deal found 3/13![Southwest logo]()
$351
This United Airlines deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/26:35 am
JAX
- MCI
1 stop8h 26m
United Airlines
Tue 5/59:45 am
MCI
- JAX
2 stops9h 17m
United Airlines
Deal found 3/12![United Airlines logo]()
$403
This American Airlines deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/173:52 pm
JAX
- SGF
2 stops7h 46m
American Airlines
Sun 4/196:24 pm
SGF
- JAX
1 stop4h 57m
American Airlines
Deal found 3/17![American Airlines logo]()
$562
This Delta deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/82:40 pm
JAX
- SGF
1 stop4h 26m
Delta
Sat 5/164:00 pm
SGF
- JAX
1 stop5h 26m
Delta
Deal found 3/16![Delta logo]()
$425
This Southwest deal was found by Cheapflights users on 3/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/75:35 am
JAX
- MCI
2 stops6h 55m
Southwest
Tue 5/121:40 pm
MCI
- JAX
2 stops6h 50m
Southwest
Deal found 3/14![Southwest logo]()
$361
This United Airlines deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/99:20 am
JAX
- SGF
2 stops9h 04m
United Airlines
Mon 4/132:52 pm
SGF
- JAX
1 stop6h 12m
United Airlines
Deal found 3/12![United Airlines logo]()
$405
This Delta deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/175:39 pm
JAX
- SGF
1 stop4h 28m
Delta
Sun 4/196:55 pm
SGF
- JAX
1 stop4h 04m
Delta
Deal found 3/17![Delta logo]()
$443
This Southwest deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/15:10 am
JAX
- MCI
1 stop6h 20m
Southwest
Mon 5/43:20 pm
MCI
- JAX
1 stop5h 45m
Southwest
Deal found 3/16![Southwest logo]()
$386
This United Airlines deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/129:00 am
JAX
- SGF
1 stop6h 13m
United Airlines
Wed 5/203:00 pm
SGF
- JAX
1 stop5h 50m
United Airlines
Deal found 3/13![United Airlines logo]()
$435
This Southwest deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/265:20 am
JAX
- MCI
1 stop5h 45m
Southwest
Thu 4/3012:05 pm
MCI
- JAX
1 stop3h 50m
Southwest
Deal found 3/16![Southwest logo]()
$386
This United Airlines deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/1612:24 pm
JAX
- JLN
2 stops12h 20m
United Airlines
Sun 4/191:58 pm
JLN
- JAX
1 stop6h 48m
United Airlines
Deal found 3/12![United Airlines logo]()
$460
This Southwest deal was found by Cheapflights users on 3/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/305:10 am
JAX
- MCI
1 stop9h 10m
Southwest
Sun 5/32:55 pm
MCI
- JAX
2 stops7h 20m
Southwest
Deal found 3/14![Southwest logo]()
$391
This United Airlines deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/128:00 am
JAX
- JLN
1 stop6h 37m
United Airlines
Wed 5/209:06 am
JLN
- JAX
1 stop7h 39m
United Airlines
Deal found 3/13![United Airlines logo]()
$470
This Southwest deal was found by Cheapflights users on 3/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/15:35 am
JAX
- MCI
2 stops6h 55m
Southwest
Wed 6/311:55 am
MCI
- JAX
2 stops8h 35m
Southwest
Deal found 3/15![Southwest logo]()
$406
This United Airlines deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/138:00 am
JAX
- JLN
1 stop6h 37m
United Airlines
Wed 5/209:06 am
JLN
- JAX
1 stop7h 39m
United Airlines
Deal found 3/13![United Airlines logo]()
$470
This Southwest deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/228:55 pm
JAX
- MCI
1 stop4h 15m
Southwest
Wed 6/245:20 am
MCI
- JAX
2 stops7h 55m
Southwest
Deal found 3/13![Southwest logo]()
$412
Last-minute flights from Jacksonville to MissouriDiscover last-minute flight deals from Jacksonville to Missouri. Data last updated March 17, 2026 and is based on user searches.
Discover last-minute flight deals from Jacksonville to Missouri. Data last updated March 17, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/318:00 am
JAX
- SGF
1 stop5h 28m
American Airlines
Sat 4/47:15 am
SGF
- JAX
1 stop7h 56m
American Airlines
Deal found 3/16![American Airlines logo]()
$319
This American Airlines deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/11:44 pm
JAX
- SGF
1 stop5h 06m
American Airlines
Mon 4/206:24 pm
SGF
- JAX
1 stop4h 57m
American Airlines
Deal found 3/16![American Airlines logo]()
$334
This American Airlines deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/72:35 pm
JAX
- STL
1 stop5h 55m
American Airlines
Fri 4/176:55 pm
STL
- JAX
1 stop4h 26m
American Airlines
Deal found 3/12![American Airlines logo]()
$297
This American Airlines deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/77:14 pm
JAX
- MCI
1 stop5h 45m
American Airlines
Thu 4/96:28 pm
MCI
- JAX
1 stop4h 53m
American Airlines
Deal found 3/12![American Airlines logo]()
$332
This United Airlines deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/73:15 pm
JAX
- MCI
1 stop5h 30m
United Airlines
Thu 4/98:00 am
MCI
- JAX
2 stops9h 18m
United Airlines
Deal found 3/12![United Airlines logo]()
$337
This American Airlines deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/96:12 pm
JAX
- SGF
1 stop4h 42m
American Airlines
Mon 4/136:24 pm
SGF
- JAX
1 stop4h 57m
American Airlines
Deal found 3/12![American Airlines logo]()
$309
This Southwest deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/103:35 pm
JAX
- STL
Nonstop2h 15m
Southwest
Mon 4/131:55 pm
STL
- JAX
Nonstop2h 00m
Southwest
Deal found 3/12![Southwest logo]()
$304
This Delta deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/115:30 am
JAX
- STL
1 stop4h 32m
Delta
Tue 4/147:25 am
STL
- JAX
1 stop3h 44m
Delta
Deal found 3/12![Delta logo]()
$299
This Southwest deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/148:20 am
JAX
- STL
Nonstop2h 15m
Southwest
Wed 4/1510:15 am
STL
- JAX
Nonstop2h 00m
Southwest
Deal found 3/16![Southwest logo]()
$291
This American Airlines deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/145:45 am
JAX
- STL
1 stop7h 02m
American Airlines
Tue 4/213:24 pm
STL
- JAX
1 stop7h 00m
American Airlines
Deal found 3/16![American Airlines logo]()
$311
This American Airlines deal was found by Cheapflights users on 3/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/256:00 am
JAX
- SGF
1 stop6h 04m
American Airlines
Sat 5/212:00 pm
SGF
- JAX
1 stop8h 02m
American Airlines
Deal found 3/14![American Airlines logo]()
$281
This Southwest deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/298:20 am
JAX
- STL
Nonstop2h 15m
Southwest
Sat 5/28:45 am
STL
- JAX
Nonstop2h 00m
Southwest
Deal found 3/16![Southwest logo]()
$283
One-way flights from Jacksonville to MissouriSearch for one-way flight options from Jacksonville to Missouri. Find affordable one-way fares based on user searches. Data last updated March 17, 2026.
Search for one-way flight options from Jacksonville to Missouri. Find affordable one-way fares based on user searches. Data last updated March 17, 2026.
This Southwest deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/128:20 am
JAX
- STL
Nonstop2h 15m
Southwest
Deal found 3/13![Southwest logo]()
$130
This Kiwi.com deal was found by Cheapflights users on 3/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/306:25 pm
JAX
- STL
1 stop13h 25m
Frontier
Deal found 3/15![Frontier logo]()
$138
This Delta deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/135:05 am
JAX
- STL
1 stop5h 39m
Delta
Deal found 3/13![Delta logo]()
$145
This Southwest deal was found by Cheapflights users on 3/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/303:35 pm
JAX
- STL
Nonstop2h 15m
Southwest
Deal found 3/14![Southwest logo]()
$146
This Kiwi.com deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/146:30 pm
JAX
- STL
1 stop15h 25m
Frontier
Deal found 3/13![Frontier logo]()
$150
This Kiwi.com deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/196:25 pm
JAX
- STL
1 stop13h 25m
Frontier
Deal found 3/12![Frontier logo]()
$151
This Kiwi.com deal was found by Cheapflights users on 3/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/1310:26 pm
JAX
- STL
2 stops33h 24m
Frontier
Deal found 3/15![Frontier logo]()
$153
This Kiwi.com deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/99:45 pm
JAX
- STL
2 stops36h 10m
Frontier
Deal found 3/13![Frontier logo]()
$155
This Delta deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/147:30 am
JAX
- STL
1 stop4h 04m
Delta
Deal found 3/16![Delta logo]()
$156
This American Airlines deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/292:09 pm
JAX
- MCI
1 stop8h 47m
American Airlines
Deal found 3/12![American Airlines logo]()
$160
This Southwest deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/146:30 am
JAX
- MCI
1 stop4h 20m
Southwest
Deal found 3/16![Southwest logo]()
$168
This United Airlines deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/96:35 am
JAX
- MCI
1 stop6h 24m
United Airlines
Deal found 3/12![United Airlines logo]()
$173
Find flight deals from Jacksonville to Missouri
Keep the following information in mind while searching for Jacksonville to Missouri flight deals. Data was last updated March 17, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $281 (American Airlines) |
One-way from | $130 (Southwest) |
Popular in | May |
Cheapest in | July |
Average price | $443 |
Good round-trip deal | $394 or less |
Good one-way deal | $224 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Jacksonville to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 17, 2026.
Use the filters below to find and compare flights from Jacksonville to Missouri that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Quickest round-trip
JacksonvilleSt. Louis
JAX - STL
JAXSTL
Jacksonville
Tue 4/14
8:20 am-9:35 am
Nonstop2h 15m
Lambert-St Louis
Wed 4/15
10:15 am-1:15 pm
Nonstop2h 00m
$291
JacksonvilleSpringfield
JAX - SGF
JAXSGF
Jacksonville
Sun 8/2
2:30 pm-6:10 pm
1 stop4h 40m
Springfield-Branson
Sat 8/8
6:00 am-1:37 pm
1 stop6h 37m
$295
JacksonvilleSt. Louis
JAX - STL
JAXSTL
Jacksonville
Wed 5/13
7:10 pm-10:00 pm
1 stop3h 50m
Lambert-St Louis
Sun 5/17
5:35 pm-11:15 pm
1 stop4h 40m
$318
JacksonvilleSt. Louis
JAX - STL
JAXSTL
Jacksonville
Fri 5/1
5:25 pm-10:30 pm
1 stop6h 05m
Lambert-St Louis
Sun 5/3
7:45 am-2:38 pm
1 stop5h 53m
$325
JacksonvilleSt. Louis
JAX - STL
JAXSTL
Jacksonville
Fri 6/12
5:30 am-8:07 am
1 stop3h 37m
Lambert-St Louis
Sun 6/21
7:05 pm-1:08 am
1 stop5h 03m
$325
JacksonvilleSt. Louis
JAX - STL
JAXSTL
Jacksonville
Tue 4/7
5:45 am-11:47 am
1 stop7h 02m
Lambert-St Louis
Fri 4/17
6:55 pm-12:21 am
1 stop4h 26m
$328
JacksonvilleSt. Louis
JAX - STL
JAXSTL
Jacksonville
Thu 6/4
2:15 pm-8:50 pm
2 stops7h 35m
Lambert-St Louis
Sun 6/7
5:30 pm-8:30 pm
Nonstop2h 00m
$339
JacksonvilleSt. Louis
JAX - STL
JAXSTL
Jacksonville
Fri 5/1
3:25 pm-10:40 pm
2 stops8h 15m
Lambert-St Louis
Sun 5/3
9:55 pm-1:50 pm
2 stops14h 55m
$341
JacksonvilleSt. Louis
JAX - STL
JAXSTL
Jacksonville
Sun 5/24
6:10 pm-7:30 pm
Nonstop2h 20m
Lambert-St Louis
Mon 5/25
4:40 pm-10:05 pm
1 stop4h 25m
$341
JacksonvilleSt. Louis
JAX - STL
JAXSTL
Jacksonville
Tue 5/5
5:00 pm-10:56 pm
1 stop6h 56m
Lambert-St Louis
Wed 5/6
9:21 am-8:02 pm
2 stops9h 41m
$344
Showing 1-10 of 54 resultsSorted by cheapest first
Best time to book a flight from Jacksonville to Missouri
Have a flexible travel schedule? Discover the best time to fly to Missouri from Jacksonville with our price prediction graph.
JAX-SGF
JAX-STL
JAX-MCI
JAX-JLN
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Jacksonville to Missouri
JAX-USMO
JAX-SGF
JAX-STL
JAX-MCI
JAX-JLN
What is the cheapest month to book a flight from Jacksonville to Missouri?
Currently, April is the cheapest month in which you can book a flight from Jacksonville to Missouri (average of $139). Flying from Jacksonville to Missouri in February is currently the most expensive (average of $249). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from JAX to MO?
Find hourly flight availability from Jacksonville to Missouri. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated March 17, 2026.
It’s optimal to fly from Jacksonville to Missouri in the evening. By choosing this option you can save up to 17% on the cost of your flight, compared to a flight at noon.
What is the cheapest day to fly from Jacksonville to Missouri?
Use this chart to determine the cheapest time to fly round-trip from Jacksonville to Missouri. Price data was last updated on March 14, 2026.
Travelers seeking maximum savings on their Jacksonville to Missouri flight should consider departing on Thursday evenings when fares are most often at their lowest. Wednesday at noon flights should be avoided if possible as fares are typically the most expensive at this time.
Reviews of airlines servicing Missouri
Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated March 17, 2026.
Peruse reviews from past customers who have flown with Southwest,Delta, andUnited Airlines from Jacksonville to Missouri to help guide your decision. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Boarding
8.1
Comfort
8.0
Entertainment
7.5
Crew
8.6
Overall
8.0
Food
7.0
Reviews
1 / 20
10.0
ExcellentAnonymous,Mar 2026
KOA - HNL
Boarding
8.1
Comfort
8.0
Entertainment
7.5
Crew
8.6
Overall
8.0
Food
7.0
Reviews
1 / 20
10.0
ExcellentAnonymous,Mar 2026
KOA - HNL
Boarding
8.1
Comfort
8.0
Entertainment
7.5
Crew
8.6
Overall
8.0
Food
7.0
Reviews
1 / 20
10.0
ExcellentAnonymous,Mar 2026
KOA - HNL
Boarding
8.1
Comfort
8.0
Entertainment
7.5
Crew
8.6
Overall
8.0
Food
7.0
Reviews
1 / 20
10.0
ExcellentAnonymous,Mar 2026
KOA - HNL
Boarding
8.1
Comfort
8.0
Entertainment
7.5
Crew
8.6
Overall
8.0
Food
7.0
Reviews
1 / 20
10.0
ExcellentAnonymous,Mar 2026
KOA - HNL
Related info for your journey
Find useful and relevant information for your journey from Jacksonville to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Jacksonville to Missouri
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Complete your trip
Complete your trip to Missouri by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Jacksonville to Missouri by cabin class
Find flights from Jacksonville to Missouri, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Jacksonville and Missouri flights
Browse other Jacksonville and Missouri flight options. Last updated on March 17, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Jacksonville to Missouri flights
Consider these flights traveling from Jacksonville to Missouri.
Top 4 airlines flying from Jacksonville to Missouri
Discover the top 4 airlines that operate flights from Jacksonville to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 17, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$176 | Average$364 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$214 | Average$336 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$233 | Average$396 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$308 | Average$363 | FlexibilityNo cancel fee | On-time69% |