HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Missouri

$62+ Cheap flights from Jacksonville (JAX) to Missouri

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/30. Fares are subject to change and may not be available on all flights or dates of travel.
JAX — STL
Jan 11 — Jan 181
Sun 1/11
Sun 1/18
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Jacksonville to Missouri with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Jacksonville to Missouri

Cheapest flights from Jacksonville to Missouri
Explore the most affordable flight options available from Jacksonville to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 12, 2025.

This Delta deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/313:12 pmJAX - STL
1 stop8h 04mDelta
Thu 1/17:00 amSTL - JAX
1 stop4h 38mDelta
Deal found 12/10$337
This American Airlines deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/319:33 amJAX - STL
2 stops7h 50mAmerican Airlines
Thu 1/15:30 amSTL - JAX
1 stop5h 26mAmerican Airlines
Deal found 12/10$342
This American Airlines deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/2012:21 pmJAX - STL
1 stop8h 12mAmerican Airlines
Sat 1/35:00 amSTL - JAX
1 stop5h 59mAmerican Airlines
Deal found 12/11$344
This Delta deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/122:52 pmJAX - SGF
1 stop4h 21mDelta
Sat 12/134:08 pmSGF - JAX
1 stop7h 03mDelta
Deal found 12/10$359
This American Airlines deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/1211:16 amJAX - SGF
1 stop6h 49mAmerican Airlines
Sat 12/132:02 pmSGF - JAX
2 stops8h 55mAmerican Airlines
Deal found 12/10$364
This Delta deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/266:41 pmJAX - STL
1 stop6h 01mDelta
Sun 1/47:02 pmSTL - JAX
1 stop3h 54mDelta
Deal found 12/10$367
This American Airlines deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/256:00 amJAX - STL
1 stop4h 59mAmerican Airlines
Mon 12/295:00 amSTL - JAX
1 stop5h 59mAmerican Airlines
Deal found 12/10$397
This Southwest deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/298:40 pmJAX - STL
Nonstop2h 15mSouthwest
Fri 1/26:45 amSTL - JAX
1 stop9h 55mSouthwest
Deal found 12/11$399
This Southwest deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/268:40 pmJAX - STL
Nonstop2h 15mSouthwest
Sun 1/45:40 amSTL - JAX
1 stop7h 20mSouthwest
Deal found 12/10$404
This American Airlines deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/1211:16 amJAX - SGF
1 stop5h 22mAmerican Airlines
Sun 12/146:34 pmSGF - JAX
1 stop4h 23mAmerican Airlines
Deal found 12/11$409
This American Airlines deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/176:00 amJAX - STL
1 stop4h 32mAmerican Airlines
Thu 12/185:17 amSTL - JAX
1 stop5h 14mAmerican Airlines
Deal found 12/11$409
This United Airlines deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/234:39 pmJAX - MCI
1 stop6h 11mUnited Airlines
Wed 12/314:40 pmMCI - JAX
1 stop5h 50mUnited Airlines
Deal found 12/10$414

Find flight deals from Jacksonville to Missouri

Keep the following information in mind while searching for Jacksonville to Missouri flight deals. Data was last updated December 12, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$206
(Delta)

One-way from

$62
(Trip.com)

Popular in

March

Cheapest in

July

Average price

$386

Good round-trip deal

$377 or less

Good one-way deal

$192 or less
Provider with most accurate pricing for Jacksonville-Lambert-St Louis flight deals.
Search Deals
Provider most trusted by Cheapflights users for Jacksonville-Lambert-St Louis flights.
Search Deals
From Jacksonville to Missouri
Search Deals
One-way flight from Jacksonville to Missouri
Search Deals
Highest demand for flights based on searches. 6% potential increase in price ($23 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 3% potential price decrease ($10 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
Search Deals
Price to beat on a round-trip flight from Jacksonville to Missouri.
Search Deals
Price to beat on a one-way flight from Jacksonville to Missouri.
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Jacksonville to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 12, 2025.
Use the filters below to find and compare flights from Jacksonville to Missouri that are best for you.

Fly from

Jacksonville

Fly to

Missouri

Route

Depart

Return

Price

JacksonvilleSpringfield

JAX - SGF

JAXSGF

Jacksonville

Thu 1/15

6:30 am-11:20 am

1 stop5h 50m

Springfield-Branson

Tue 1/20

5:00 pm-11:58 pm

1 stop5h 58m

$206

JacksonvilleSpringfield

JAX - SGF

JAXSGF

Jacksonville

Thu 1/15

7:03 am-11:49 am

1 stop5h 46m

Springfield-Branson

Tue 1/20

8:18 am-3:41 pm

1 stop6h 23m

$206

JacksonvilleSpringfield

JAX - SGF

JAXSGF

Jacksonville

Thu 1/15

6:35 am-2:38 pm

2 stops9h 03m

Springfield-Branson

Tue 1/20

3:00 pm-9:47 pm

1 stop5h 47m

$214

JacksonvilleSpringfield

JAX - SGF

JAXSGF

Jacksonville

Tue 1/20

7:03 am-11:49 am

1 stop5h 46m

Springfield-Branson

Sat 1/24

5:39 pm-11:26 pm

1 stop4h 47m

$222

JacksonvilleKansas City

JAX - MCI

JAXMCI

Jacksonville

Fri 1/16

8:17 pm-4:09 pm

2 stops20h 52m

Kansas City

Mon 1/19

11:41 am-7:22 pm

1 stop6h 41m

$226

JacksonvilleSpringfield

JAX - SGF

JAXSGF

Jacksonville

Wed 5/27

11:17 am-5:19 pm

1 stop7h 02m

Springfield-Branson

Wed 6/3

8:50 am-4:22 pm

1 stop6h 32m

$280

JacksonvilleSt. Louis

JAX - STL

JAXSTL

Jacksonville

Wed 2/4

5:05 pm-10:00 pm

1 stop5h 55m

Lambert-St Louis

Thu 2/5

6:00 am-3:38 pm

1 stop8h 38m

$295

JacksonvilleSpringfield

JAX - SGF

JAXSGF

Jacksonville

Tue 1/20

1:45 pm-9:58 pm

2 stops9h 13m

Springfield-Branson

Sat 1/24

7:45 am-10:52 pm

2 stops14h 07m

$300

JacksonvilleKansas City

JAX - MCI

JAXMCI

Jacksonville

Wed 1/14

11:53 am-6:03 pm

2 stops7h 10m

Kansas City

Sun 1/18

7:19 am-3:41 pm

2 stops7h 22m

$303

JacksonvilleKansas City

JAX - MCI

JAXMCI

Jacksonville

Thu 1/15

11:24 am-2:55 pm

1 stop4h 31m

Kansas City

Tue 1/20

1:22 pm-6:52 pm

1 stop4h 30m

$305

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/10

Showing 1-10 of 60 results
1
2
3
...
6

Best time to book a flight from Jacksonville to Missouri

Have a flexible travel schedule? Discover the best time to fly to Missouri from Jacksonville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Jacksonville to Missouri

What is the cheapest month to book a flight from Jacksonville to Missouri?

Currently, April is the cheapest month in which you can book a flight from Jacksonville to Missouri (average of $139). Flying from Jacksonville to Missouri in November is currently the most expensive (average of $226). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from JAX to MO?

Find hourly flight availability from Jacksonville to Missouri. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 12, 2025.

It’s optimal to fly from Jacksonville to Missouri in the evening. By choosing this option you can save up to 37% on the cost of your flight, compared to a flight in the morning.

What is the cheapest day to fly from Jacksonville to Missouri?

Use this chart to determine the cheapest time to fly round-trip from Jacksonville to Missouri. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their Jacksonville to Missouri flight should consider departing on Friday afternoons when fares are most often at their lowest. Sunday at noon flights should be avoided if possible as fares are typically the most expensive at this time.

Reviews of airlines servicing Missouri

Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated December 12, 2025.
Peruse reviews from past customers who have flown with Southwest, Delta, and American Airlines from Jacksonville to Missouri to help guide your decision. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
7.9
Good
4,253 reviews

Comfort

8.0

Crew

8.6

Overall

7.9

Entertainment

7.5

Food

7.0

Boarding

8.1

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
Southwest
7.9
Good
4,253 reviews
Southwest
7.9
Good
4,253 reviews

Comfort

8.0

Crew

8.6

Overall

7.9

Entertainment

7.5

Food

7.0

Boarding

8.1

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
Delta
7.9
Good
8,008 reviews
Southwest
7.9
Good
4,253 reviews

Comfort

8.0

Crew

8.6

Overall

7.9

Entertainment

7.5

Food

7.0

Boarding

8.1

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
American Airlines
7.2
Good
11,050 reviews
Southwest
7.9
Good
4,253 reviews

Comfort

8.0

Crew

8.6

Overall

7.9

Entertainment

7.5

Food

7.0

Boarding

8.1

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

Related info for your journey

Find useful and relevant information for your journey from Jacksonville to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Jacksonville to Missouri?

    Located just 11.2 mi from the city center, Jacksonville (JAX) is the airport most travelers will use when flying to Missouri from Jacksonville.

  • How popular is this Jacksonville to Missouri flight route?

    Within the past month, 19 users have taken a look at flights from Jacksonville to Missouri.

  • How long is the flight from Jacksonville to Missouri?

    For as low as $206, Delta can have you in Missouri from Jacksonville in 5h 46m. There are 816 mi between Jacksonville and Missouri. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines to fly from Jacksonville to Missouri one-way?

    For one-way options, check prices for American Airlines. According to our data, you can fly for as low as $99. Users have also found prices from $101 and $109 on Southwest and Delta, respectively.

  • What are the most popular routes from Jacksonville to Missouri?

    When deciding which route to take from Jacksonville to Missouri consider Jacksonville - Lambert-St Louis, Jacksonville - Kansas City or Jacksonville - Springfield-Branson as they are the most popular.

  • What are the cheapest flights from Jacksonville to Missouri?

    The cheapest flight price from Jacksonville to Missouri is $174. On average you can expect to pay $370. The most popular route, (Jacksonville - Lambert-St Louis), can usually be booked for $317.

  • Can I find deals for flights from Jacksonville to Missouri that include hotel bookings?

    Yes. In addition to deals on Jacksonville to Missouri flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Jacksonville to Missouri?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Jacksonville to Missouri.

  • Can I find deals for business class flights from Jacksonville to Missouri?

    Yes. Cheapflights offers flight deals from Jacksonville to Missouri by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Jacksonville to Missouri?

    Currently, April is the cheapest month in which you can book a flight from Jacksonville to Missouri (average of $139). Flying from Jacksonville to Missouri in November is currently the most expensive (average of $226). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Jacksonville to Missouri

See prices for flight routes from nearby airports that may be better suited for you.
Miami to John F Kennedy Intl flights
Fort Lauderdale to John F Kennedy Intl flights
Miami to LaGuardia flights
Orlando to John F Kennedy Intl flights
Fort Lauderdale to Newark flights
Orlando to Newark flights
Fort Lauderdale to LaGuardia flights
West Palm Beach to Newark flights
Miami to Newark flights
Orlando to Las Vegas flights
Orlando to LaGuardia flights
Fort Lauderdale to Dallas/Fort Worth flights
Orlando to Dallas/Fort Worth flights
Tampa to LaGuardia flights
West Palm Beach to John F Kennedy Intl flights
Tampa to John F Kennedy Intl flights
Miami to Denver flights
Miami to Dallas/Fort Worth flights
Fort Lauderdale to Las Vegas flights
Orlando to Denver flights
Fort Lauderdale to Hobby flights
Miami to Hobby flights
Tampa to Newark flights
Orlando to Los Angeles flights
Miami to Las Vegas flights
West Palm Beach to LaGuardia flights
Tampa to Las Vegas flights
Miami to Los Angeles flights
Fort Lauderdale to Los Angeles flights
Tampa to Denver flights
Fort Lauderdale to Atlanta flights
Fort Lauderdale to George Bush Intcntl flights
Miami to George Bush Intcntl flights
Fort Lauderdale to Denver flights
Orlando to Seattle flights
Jacksonville to LaGuardia flights
Miami to Atlanta flights
Jacksonville to John F Kennedy Intl flights
Tampa to Dallas/Fort Worth flights
Tampa to O'Hare Intl flights
Orlando to Hobby flights
Orlando to Reagan-National flights
Orlando to Dulles Intl flights
Tampa to Dulles Intl flights
West Palm Beach to Hobby flights
Fort Lauderdale to Boston flights
Orlando to O'Hare Intl flights
Tampa to Atlanta flights
Fort Lauderdale to Baltimore flights
Fort Myers to Newark flights

Top 3 airlines flying from Jacksonville to Missouri

Discover the top 3 airlines that operate flights from Jacksonville to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 12, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$194Average$325FlexibilityNo cancel feeOn-timeN/A
SouthwestCheapest$214Average$337FlexibilityNo cancel feeOn-time63%
American AirlinesCheapest$218Average$359FlexibilityNo cancel feeOn-time71%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.