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$61+ Cheap flights from Jacksonville (JAX) to Missouri

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/20. Fares are subject to change and may not be available on all flights or dates of travel.
JAX — STL
Feb 28 — Mar 71
Sat 2/28
Sat 3/7
1 adult, Economy
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Cheap flight deals from Jacksonville to Missouri

Cheapest flights from Jacksonville to Missouri
Explore the most affordable flight options available from Jacksonville to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 29, 2026.

This Kiwi.com deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/69:45 am
JAX
-
STL
2 stops25h 04m
Multiple Airlines
Mon 3/92:09 pm
STL
-
JAX
1 stop4h 24m
Multiple Airlines
Deal found 1/28$211
This Kiwi.com deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/18:18 pm
JAX
-
STL
1 stop15h 12m
Frontier
Wed 4/84:54 pm
STL
-
JAX
2 stops22h 39m
Frontier
Deal found 1/27$244
This Kiwi.com deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/138:12 pm
JAX
-
MCI
2 stops39h 18m
Multiple Airlines
Mon 2/1610:55 am
MCI
-
JAX
1 stop7h 06m
Multiple Airlines
Deal found 1/27$248
This Kiwi.com deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/18:18 pm
JAX
-
STL
1 stop15h 12m
Frontier
Sun 4/54:54 pm
STL
-
JAX
2 stops25h 39m
Frontier
Deal found 1/28$249
This Delta deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/116:46 pm
JAX
-
SGF
1 stop4h 43m
Delta
Tue 8/183:30 pm
SGF
-
JAX
1 stop4h 14m
Delta
Deal found 1/27$261
This American Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/203:55 pm
JAX
-
SGF
1 stop7h 04m
American Airlines
Mon 2/234:34 pm
SGF
-
JAX
1 stop5h 54m
American Airlines
Deal found 1/27$269
This eDestinos deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/59:04 pm
JAX
-
STL
2 stops34h 47m
Frontier
Tue 2/103:49 pm
STL
-
JAX
2 stops25h 42m
Frontier
Deal found 1/27$272
This Kiwi.com deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/138:12 pm
JAX
-
STL
1 stop11h 39m
Frontier
Mon 2/1610:11 pm
STL
-
JAX
2 stops43h 50m
Frontier
Deal found 1/27$276
This Southwest deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/246:25 am
JAX
-
STL
Nonstop2h 20m
Southwest
Thu 3/267:45 pm
STL
-
JAX
Nonstop2h 00m
Southwest
Deal found 1/28$277
This American Airlines deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/186:02 am
JAX
-
STL
1 stop5h 57m
American Airlines
Mon 3/232:19 pm
STL
-
JAX
1 stop7h 39m
American Airlines
Deal found 1/28$278
This American Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/116:00 am
JAX
-
SGF
1 stop7h 15m
American Airlines
Sun 2/1511:48 am
SGF
-
JAX
1 stop4h 31m
American Airlines
Deal found 1/27$279
This Southwest deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/16:25 am
JAX
-
STL
Nonstop2h 20m
Southwest
Wed 4/81:45 pm
STL
-
JAX
1 stop6h 30m
Southwest
Deal found 1/27$279

Find flight deals from Jacksonville to Missouri

Keep the following information in mind while searching for Jacksonville to Missouri flight deals. Data was last updated January 29, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$211
(Kiwi.com)

One-way from

$61
(Trip.com)

Popular in

March

Cheapest in

July

Average price

$375

Good round-trip deal

$347 or less

Good one-way deal

$322 or less
Provider with most accurate pricing for Jacksonville-Lambert-St Louis flight deals.
Search Deals
Provider most trusted by Cheapflights users for Jacksonville-Lambert-St Louis flights.
Search Deals
From Jacksonville to Missouri
Search Deals
One-way flight from Jacksonville to Missouri
Search Deals
Highest demand for flights based on searches. 5% potential increase in price ($18 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($8 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in January 2026
Search Deals
Price to beat on a round-trip flight from Jacksonville to Missouri.
Search Deals
Price to beat on a one-way flight from Jacksonville to Missouri.
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Jacksonville to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 29, 2026.
Use the filters below to find and compare flights from Jacksonville to Missouri that are best for you.

Fly from

Jacksonville

Fly to

Missouri

Route

Depart

Return

Price

JacksonvilleKansas City

JAX - MCI

JAXMCI

Jacksonville

Fri 2/13

8:12 pm-10:30 am

2 stops39h 18m

Kansas City

Mon 2/16

10:55 am-7:01 pm

1 stop7h 06m

$248

JacksonvilleSpringfield

JAX - SGF

JAXSGF

Jacksonville

Thu 2/26

7:30 am-11:20 am

1 stop4h 50m

Springfield-Branson

Mon 3/2

5:32 pm-10:58 pm

1 stop4h 26m

$269

JacksonvilleSpringfield

JAX - SGF

JAXSGF

Jacksonville

Fri 3/6

6:09 pm-9:59 pm

1 stop4h 50m

Springfield-Branson

Mon 3/9

11:48 am-7:17 pm

1 stop6h 29m

$269

JacksonvilleSpringfield

JAX - SGF

JAXSGF

Jacksonville

Thu 2/26

6:25 am-2:40 pm

2 stops9h 15m

Springfield-Branson

Mon 3/2

2:53 pm-9:15 pm

1 stop5h 22m

$274

JacksonvilleSpringfield

JAX - SGF

JAXSGF

Jacksonville

Fri 2/20

3:55 pm-10:31 pm

2 stops7h 36m

Springfield-Branson

Mon 2/23

4:29 pm-11:59 pm

1 stop6h 30m

$274

JacksonvilleSt. Louis

JAX - STL

JAXSTL

Jacksonville

Fri 2/13

8:12 pm-6:51 am

1 stop11h 39m

Lambert-St Louis

Mon 2/16

10:11 pm-7:01 pm

2 stops43h 50m

$276

JacksonvilleSt. Louis

JAX - STL

JAXSTL

Jacksonville

Sat 3/28

5:40 am-7:00 am

Nonstop2h 20m

Lambert-St Louis

Wed 4/1

7:15 pm-10:15 pm

Nonstop2h 00m

$277

JacksonvilleSt. Louis

JAX - STL

JAXSTL

Jacksonville

Wed 4/1

5:27 pm-10:28 pm

1 stop6h 01m

Lambert-St Louis

Wed 4/8

7:45 am-2:13 pm

1 stop5h 28m

$278

JacksonvilleSt. Louis

JAX - STL

JAXSTL

Jacksonville

Tue 3/24

7:01 am-12:44 pm

1 stop6h 43m

Lambert-St Louis

Thu 3/26

4:13 pm-12:17 am

1 stop7h 04m

$278

JacksonvilleSt. Louis

JAX - STL

JAXSTL

Jacksonville

Wed 4/1

6:25 am-7:45 am

Nonstop2h 20m

Lambert-St Louis

Wed 4/8

1:45 pm-9:15 pm

1 stop6h 30m

$279

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/28

Showing 1-10 of 57 results
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Best time to book a flight from Jacksonville to Missouri

Have a flexible travel schedule? Discover the best time to fly to Missouri from Jacksonville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Jacksonville to Missouri

What is the cheapest month to book a flight from Jacksonville to Missouri?

Currently, April is the cheapest month in which you can book a flight from Jacksonville to Missouri (average of $139). Flying from Jacksonville to Missouri in December is currently the most expensive (average of $246). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from JAX to MO?

Find hourly flight availability from Jacksonville to Missouri. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated January 29, 2026.

It’s optimal to fly from Jacksonville to Missouri in the afternoon. By choosing this option you can save up to 18% on the cost of your flight, compared to a flight at noon.

What is the cheapest day to fly from Jacksonville to Missouri?

Use this chart to determine the cheapest time to fly round-trip from Jacksonville to Missouri. Price data was last updated on January 24, 2026.

Travelers seeking maximum savings on their Jacksonville to Missouri flight should consider departing on Thursday evenings when fares are most often at their lowest. Wednesday at noon flights should be avoided if possible as fares are typically the most expensive at this time.

Reviews of airlines servicing Missouri

Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated January 29, 2026.
Peruse reviews from past customers who have flown with Southwest, Delta, and American Airlines from Jacksonville to Missouri to help guide your decision. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,267 reviews

Entertainment

7.5

Crew

8.6

Comfort

8.0

Overall

8.0

Boarding

8.1

Food

7.0

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
Southwest
8.0
Very good
4,267 reviews
Southwest
8.0
Very good
4,267 reviews

Entertainment

7.5

Crew

8.6

Comfort

8.0

Overall

8.0

Boarding

8.1

Food

7.0

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
Delta
7.9
Good
8,127 reviews
Southwest
8.0
Very good
4,267 reviews

Entertainment

7.5

Crew

8.6

Comfort

8.0

Overall

8.0

Boarding

8.1

Food

7.0

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
American Airlines
7.2
Good
11,206 reviews
Southwest
8.0
Very good
4,267 reviews

Entertainment

7.5

Crew

8.6

Comfort

8.0

Overall

8.0

Boarding

8.1

Food

7.0

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

Related info for your journey

Find useful and relevant information for your journey from Jacksonville to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Jacksonville to Missouri?

    Located just 11.2 mi from the city center, Jacksonville (JAX) is the airport most travelers will use when flying to Missouri from Jacksonville.

  • How popular is this Jacksonville to Missouri flight route?

    Within the past month, 16 users have taken a look at flights from Jacksonville to Missouri.

  • How long is the flight from Jacksonville to Missouri?

    For as low as $269, Delta can have you in Missouri from Jacksonville in 4h 50m. There are 816 mi between Jacksonville and Missouri. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines to fly from Jacksonville to Missouri one-way?

    For one-way options, check prices for United Airlines. According to our data, you can fly for as low as $75. Users have also found prices from $99 and $101 on American Airlines and Southwest, respectively.

  • What are the most popular routes from Jacksonville to Missouri?

    When deciding which route to take from Jacksonville to Missouri consider Jacksonville - Kansas City, Jacksonville - Lambert-St Louis or Jacksonville - Springfield-Branson as they are the most popular.

  • What are the cheapest flights from Jacksonville to Missouri?

    The cheapest flight price from Jacksonville to Missouri is $215. On average you can expect to pay $433. The most popular route, (Jacksonville - Kansas City), can usually be booked for $205.

  • Can I find deals for flights from Jacksonville to Missouri that include hotel bookings?

    Yes. In addition to deals on Jacksonville to Missouri flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Jacksonville to Missouri?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Jacksonville to Missouri.

  • Can I find deals for business class flights from Jacksonville to Missouri?

    Yes. Cheapflights offers flight deals from Jacksonville to Missouri by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Jacksonville to Missouri?

    Currently, April is the cheapest month in which you can book a flight from Jacksonville to Missouri (average of $139). Flying from Jacksonville to Missouri in December is currently the most expensive (average of $246). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top 3 airlines flying from Jacksonville to Missouri

Discover the top 3 airlines that operate flights from Jacksonville to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 29, 2026.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$176Average$346FlexibilityNo cancel feeOn-timeN/A
SouthwestCheapest$214Average$334FlexibilityNo cancel feeOn-time63%
American AirlinesCheapest$218Average$382FlexibilityNo cancel feeOn-time71%

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