$127+ Cheap flights from Irvine, CA to Missouri
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/10. Fares are subject to change and may not be available on all flights or dates of travel.
LAX — STL
Oct 17 — Oct 241
Round-trip
1 adult, Economy
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Find cheap flights from Irvine to Missouri with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Cheapest flights from Irvine to MissouriExplore the most affordable flight options available from Irvine to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 17, 2026.
Explore the most affordable flight options available from Irvine to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 17, 2026.
This Kiwi.com deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/39:59 pm -
1 stop12h 36m
Mon 12/141:25 pm -
1 stop9h 40m
Deal found 9/13![Multiple Airlines logo]()
$254
This Kiwi.com deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/2711:42 am -
1 stop6h 05m
Wed 11/48:43 pm -
1 stop5h 40m
Deal found 9/12![Frontier logo]()
$260
This Kiwi.com deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/76:05 am -
1 stop11h 32m
Mon 10/128:43 pm -
2 stops18h 23m
Deal found 9/16![Frontier logo]()
$261
This Expedia deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/106:02 am -
1 stop15h 57m
Sat 10/178:43 pm -
1 stop5h 46m
Deal found 9/16![Multiple Airlines logo]()
$262
This CheapOair deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/811:40 am -
1 stop6h 08m
Tue 10/138:43 pm -
1 stop5h 46m
Deal found 9/14![Frontier logo]()
$263
This Kiwi.com deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/76:05 am -
1 stop11h 32m
Thu 10/158:43 pm -
1 stop5h 46m
Deal found 9/16![Frontier logo]()
$264
This Kiwi.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/288:14 am -
1 stop7h 04m
Wed 10/288:43 pm -
1 stop5h 40m
Deal found 9/15![Multiple Airlines logo]()
$265
This Kiwi.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/1011:40 am -
1 stop6h 08m
Thu 10/158:43 pm -
1 stop19h 57m
Deal found 9/15![Frontier logo]()
$266
This Kiwi.com deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/911:40 am -
1 stop6h 08m
Wed 10/148:43 pm -
1 stop5h 46m
Deal found 9/16![Frontier logo]()
$267
This Kiwi.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/66:05 am -
1 stop11h 32m
Mon 10/128:43 pm -
2 stops18h 23m
Deal found 9/15![Frontier logo]()
$268
This Orbitz deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/56:05 am -
1 stop11h 32m
Tue 10/68:32 pm -
1 stop19h 42m
Deal found 9/14![Frontier logo]()
$269
This Kiwi.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/266:05 am -
1 stop11h 43m
Fri 10/308:43 pm -
1 stop20h 03m
Deal found 9/15![Frontier logo]()
$270
Best flights from Irvine to MissouriDiscover carefully curated flight deals from Irvine to Missouri that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 17, 2026.
Discover carefully curated flight deals from Irvine to Missouri that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 17, 2026.
This Southwest deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/288:10 am -
1 stop7h 10m
Sat 10/3110:40 am -
Nonstop3h 35m
Deal found 9/16![Southwest logo]()
$323
This American Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/2911:27 pm -
1 stop8h 31m
Sun 11/17:48 pm -
1 stop6h 06m
Deal found 9/17![American Airlines logo]()
$348
This Delta deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/126:40 pm -
Nonstop3h 08m
Tue 11/175:35 pm -
1 stop8h 23m
Deal found 9/17![Delta logo]()
$354
This United Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/302:29 pm -
1 stop7h 15m
Mon 11/21:33 pm -
1 stop7h 55m
Deal found 9/13![United Airlines logo]()
$354
This Southwest deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/165:55 pm -
Nonstop3h 35m
Fri 10/239:55 pm -
Nonstop4h 00m
Deal found 9/16![Southwest logo]()
$359
This KAYAK deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/104:59 pm -
2 stops17h 51m
Sat 10/179:40 am -
2 stops13h 05m
Deal found 9/16![Multiple Airlines logo]()
$746
This Delta deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/72:00 pm -
Nonstop3h 08m
Mon 11/96:36 am -
1 stop9h 52m
Deal found 9/16![Delta logo]()
$378
This United Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/24:15 pm -
1 stop5h 27m
Sat 10/104:53 pm -
1 stop8h 37m
Deal found 9/16![United Airlines logo]()
$411
This American Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/2412:06 pm -
1 stop7h 23m
Thu 12/316:00 am -
1 stop9h 17m
Deal found 9/13![American Airlines logo]()
$453
This United Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/79:17 am -
Nonstop3h 28m
Tue 11/101:34 pm -
1 stop6h 05m
Deal found 9/16![United Airlines logo]()
$413
This Southwest deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/155:55 pm -
Nonstop3h 35m
Sun 10/186:45 am -
1 stop5h 50m
Deal found 9/15![Southwest logo]()
$416
This Southwest deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/228:05 am -
2 stops6h 55m
Sat 10/248:25 am -
2 stops7h 40m
Deal found 9/14![Southwest logo]()
$416
This United Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/302:19 pm -
1 stop6h 59m
Sun 10/45:30 am -
1 stop6h 02m
Deal found 9/15![United Airlines logo]()
$429
This Delta deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/159:59 am -
2 stops9h 42m
Mon 1/1810:30 am -
2 stops12h 13m
Deal found 9/14![Delta logo]()
$483
This United Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 1/2512:19 am -
1 stop8h 36m
Sat 1/309:00 am -
1 stop7h 53m
Deal found 9/16![United Airlines logo]()
$438
This Delta deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/226:00 am -
1 stop6h 41m
Tue 12/16:03 am -
1 stop6h 57m
Deal found 9/16![Delta logo]()
$486
This Southwest deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/215:30 pm -
Nonstop3h 10m
Sun 10/259:25 pm -
Nonstop3h 45m
Deal found 9/16![Southwest logo]()
$446
This United Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/311:17 pm -
1 stop8h 42m
Sat 11/146:01 am -
1 stop9h 08m
Deal found 9/13![United Airlines logo]()
$444
This Southwest deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/145:30 pm -
Nonstop3h 10m
Sun 10/186:35 am -
Nonstop3h 35m
Deal found 9/15![Southwest logo]()
$446
This Delta deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/62:00 pm -
Nonstop3h 08m
Sun 11/87:00 am -
1 stop10h 15m
Deal found 9/15![Delta logo]()
$526
This United Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/114:17 pm -
1 stop5h 27m
Thu 11/266:01 am -
1 stop7h 28m
Deal found 9/15![United Airlines logo]()
$444
This Southwest deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/285:30 pm -
Nonstop3h 10m
Sun 11/16:15 pm -
1 stop7h 10m
Deal found 9/16![Southwest logo]()
$456
This United Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/311:17 pm -
1 stop8h 42m
Mon 11/166:01 am -
1 stop7h 28m
Deal found 9/13![United Airlines logo]()
$444
This Southwest deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/268:25 am -
2 stops6h 35m
Sat 10/317:00 am -
2 stops9h 05m
Deal found 9/16![Southwest logo]()
$458
This United Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/1211:17 pm -
1 stop8h 42m
Tue 11/241:33 pm -
1 stop6h 06m
Deal found 9/15![United Airlines logo]()
$444
This United Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/511:47 pm -
1 stop8h 12m
Mon 11/96:01 am -
1 stop7h 28m
Deal found 9/15![United Airlines logo]()
$444
This Southwest deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/163:25 pm -
1 stop5h 25m
Mon 10/199:55 pm -
Nonstop4h 00m
Deal found 9/13![Southwest logo]()
$499
This Southwest deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/275:30 pm -
Nonstop3h 10m
Tue 11/36:55 am -
Nonstop3h 40m
Deal found 9/12![Southwest logo]()
$503
This United Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/1610:35 pm -
1 stop9h 51m
Wed 10/214:20 pm -
Nonstop3h 50m
Deal found 9/14![United Airlines logo]()
$491
This Southwest deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/257:20 am -
2 stops8h 05m
Fri 1/15:05 am -
1 stop7h 00m
Deal found 9/13![Southwest logo]()
$518
Last-minute flights from Irvine to MissouriDiscover last-minute flight deals from Irvine to Missouri. Data last updated September 17, 2026 and is based on user searches.
Discover last-minute flight deals from Irvine to Missouri. Data last updated September 17, 2026 and is based on user searches.
This Orbitz deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/56:05 am -
1 stop11h 32m
Tue 10/68:32 pm -
1 stop19h 42m
Deal found 9/14![Frontier logo]()
$269
This Kiwi.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/66:05 am -
1 stop11h 32m
Mon 10/128:43 pm -
2 stops18h 23m
Deal found 9/15![Frontier logo]()
$268
This Kiwi.com deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/76:05 am -
1 stop11h 32m
Mon 10/128:43 pm -
2 stops18h 23m
Deal found 9/16![Frontier logo]()
$261
This Kiwi.com deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/76:05 am -
1 stop11h 32m
Thu 10/158:43 pm -
1 stop5h 46m
Deal found 9/16![Frontier logo]()
$264
This CheapOair deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/811:40 am -
1 stop6h 08m
Tue 10/138:43 pm -
1 stop5h 46m
Deal found 9/14![Frontier logo]()
$263
This Kiwi.com deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/911:40 am -
1 stop6h 08m
Wed 10/148:43 pm -
1 stop5h 46m
Deal found 9/16![Frontier logo]()
$267
This Frontier deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/911:40 am -
1 stop6h 08m
Tue 10/138:43 pm -
1 stop5h 46m
Deal found 9/16![Frontier logo]()
$271
This Expedia deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/106:02 am -
1 stop15h 57m
Sat 10/178:43 pm -
1 stop5h 46m
Deal found 9/16![Multiple Airlines logo]()
$262
This Kiwi.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/1011:40 am -
1 stop6h 08m
Thu 10/158:43 pm -
1 stop19h 57m
Deal found 9/15![Frontier logo]()
$266
This Kiwi.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/266:05 am -
1 stop11h 43m
Fri 10/308:43 pm -
1 stop20h 03m
Deal found 9/15![Frontier logo]()
$270
This Kiwi.com deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/2711:42 am -
1 stop6h 05m
Wed 11/48:43 pm -
1 stop5h 40m
Deal found 9/12![Frontier logo]()
$260
This Kiwi.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/288:14 am -
1 stop7h 04m
Wed 10/288:43 pm -
1 stop5h 40m
Deal found 9/15![Multiple Airlines logo]()
$265
One-way flights from Irvine to MissouriSearch for one-way flight options from Irvine to Missouri. Find affordable one-way fares based on user searches. Data last updated September 17, 2026.
Search for one-way flight options from Irvine to Missouri. Find affordable one-way fares based on user searches. Data last updated September 17, 2026.
This Kiwi.com deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/106:00 am -
1 stop11h 41m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/12![Frontier logo]()
$127
This Kiwi.com deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/148:00 pm -
1 stop21h 41m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/14![Frontier logo]()
$131
This Mytrip deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/1912:09 am -
2 stops17h 39m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/16![Frontier logo]()
$133
This Mytrip deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/2612:03 am -
2 stops17h 44m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/16![Frontier logo]()
$134
This Kiwi.com deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/1311:42 am -
1 stop6h 05m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/12![Frontier logo]()
$135
This Expedia deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/52:31 pm -
1 stop27h 16m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/16![Frontier logo]()
$136
This Super.com deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/811:40 am -
1 stop6h 08m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/16![Frontier logo]()
$137
This Kiwi.com deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/2012:09 am -
2 stops17h 39m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/16![Frontier logo]()
$138
This Mytrip deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/1612:09 am -
2 stops17h 39m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/16![Frontier logo]()
$139
This Kiwi.com deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/135:15 pm -
2 stops24h 33m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/14![Frontier logo]()
$140
This Frontier deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/611:42 am -
1 stop5h 32m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/16![Frontier logo]()
$140
This Priceline deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/1911:42 am -
1 stop6h 05m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/16![Frontier logo]()
$141
Find flight deals from Irvine to Missouri
Keep the following information in mind while searching for Irvine to Missouri flight deals. Data was last updated September 17, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $254 (Kiwi.com) |
One-way from | $127 (Kiwi.com) |
Popular in | March |
Cheapest in | October |
Average price | $409 |
Cheapflights Fare Finder
Customize your flight search to find flights from Irvine to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 17, 2026.
Use the filters below to find and compare flights from Irvine to Missouri that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Los AngelesSt. Louis
LAX Los Angeles - STL Lambert-St Louis
LAXSTL
Los Angeles
Tue 11/17
6:00 am-2:41 pm
1 stop6h 41m
Lambert-St Louis
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$149
Los AngelesSt. Louis
LAX Los Angeles - STL Lambert-St Louis
LAXSTL
Los Angeles
Wed 12/16
1:20 pm-10:05 pm
2 stops6h 45m
Lambert-St Louis
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$154
Los AngelesSt. Louis
LAX Los Angeles - STL Lambert-St Louis
LAXSTL
Los Angeles
Tue 12/15
1:20 pm-10:05 pm
2 stops6h 45m
Lambert-St Louis
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$154
Los AngelesKansas City
LAX Los Angeles - MCI Kansas City
LAXMCI
Los Angeles
Sat 11/14
1:30 pm-6:39 pm
Nonstop3h 09m
Kansas City
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$157
Quickest round-trip
Los AngelesKansas City
LAX Los Angeles - MCI Kansas City
LAXMCI
Los Angeles
Wed 10/28
7:40 am-12:45 pm
Nonstop3h 05m
Kansas City
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$157
Los AngelesKansas City
LAX Los Angeles - MCI Kansas City
LAXMCI
Los Angeles
Wed 11/18
6:40 pm-11:48 pm
Nonstop3h 08m
Kansas City
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$157
Los AngelesKansas City
LAX Los Angeles - MCI Kansas City
LAXMCI
Los Angeles
Sat 11/7
7:55 am-1:05 pm
Nonstop3h 10m
Kansas City
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$157
Los AngelesKansas City
LAX Los Angeles - MCI Kansas City
LAXMCI
Los Angeles
Tue 12/15
1:20 pm-6:30 pm
Nonstop3h 10m
Kansas City
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$157
Los AngelesKansas City
LAX Los Angeles - MCI Kansas City
LAXMCI
Los Angeles
Wed 11/11
1:20 pm-6:30 pm
Nonstop3h 10m
Kansas City
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$157
Los AngelesKansas City
LAX Los Angeles - MCI Kansas City
LAXMCI
Los Angeles
Sat 11/14
7:00 am-11:59 pm
2 stops14h 59m
Kansas City
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$164
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from Irvine to Missouri
Have a flexible travel schedule? Discover the best time to fly to Missouri from Irvine with our price prediction graph.
LAX-STL
LAX-MCI
LAX-SGF
LAX-COU
LAX-JLN
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Irvine to Missouri
IR9-USMO
LAX-STL
LAX-MCI
LAX-SGF
LAX-COU
What is the cheapest time of day to fly from IR9 to MO?
Find hourly flight availability from Irvine to Missouri. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 17, 2026.
One of the essential ways to save on airfare from Irvine to Missouri is to remain as flexible as possible. Flights that are at noon tend to be the most expensive. A flight in the evening could potentially save you up to 19% on airfare.
Weekly flight availability from Irvine to Missouri
Explore weekly flight availability from Irvine to Missouri. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated September 17, 2026.
The most flights from IR9 to USMO are scheduled on a Wednesday (9 on average). You will have fewer flight options on Thursday, which is when the least amount of flights are scheduled (6 on average).
How much does it cost to fly round-trip from Irvine to Missouri?
Airfare is below average for this route at the moment.
Irvine to Missouri flights typically cost between $361 and $539 in November.The cheapest round-trip price found within the last 5 days was $352 on Frontier (Nov 9-Dec 11).
What is the cheapest day to fly from Irvine to Missouri?
Use this chart to determine the cheapest time to fly round-trip from Irvine to Missouri. Price data was last updated on September 5, 2026.
Travelers seeking maximum savings on their Irvine to Missouri flight should consider departing on Wednesday afternoons when fares are most often at their lowest. Sunday evenings flights should be avoided if possible as fares are typically the most expensive at this time.
Reviews of airlines servicing Missouri
Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated September 17, 2026.
Peruse reviews from past customers who have flown with Southwest,Delta, andUnited Airlines from Irvine to Missouri to help guide your decision. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Comfort
8.0
Crew
8.6
Boarding
8.1
Entertainment
7.5
Overall
8.0
Food
7.0
Reviews
1 / 20
10.0
ExcellentCourtney,Sep 2026
DEN - STL
Comfort
8.0
Crew
8.6
Boarding
8.1
Entertainment
7.5
Overall
8.0
Food
7.0
Reviews
1 / 20
10.0
ExcellentCourtney,Sep 2026
DEN - STL
Comfort
8.0
Crew
8.6
Boarding
8.1
Entertainment
7.5
Overall
8.0
Food
7.0
Reviews
1 / 20
10.0
ExcellentCourtney,Sep 2026
DEN - STL
Comfort
8.0
Crew
8.6
Boarding
8.1
Entertainment
7.5
Overall
8.0
Food
7.0
Reviews
1 / 20
10.0
ExcellentCourtney,Sep 2026
DEN - STL
Comfort
8.0
Crew
8.6
Boarding
8.1
Entertainment
7.5
Overall
8.0
Food
7.0
Reviews
1 / 20
10.0
ExcellentCourtney,Sep 2026
DEN - STL
Comfort
8.0
Crew
8.6
Boarding
8.1
Entertainment
7.5
Overall
8.0
Food
7.0
Reviews
1 / 20
10.0
ExcellentCourtney,Sep 2026
DEN - STL
Related info for your journey
Find useful and relevant information for your journey from Irvine to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Irvine to Missouri
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Missouri by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Irvine to Missouri by cabin class
Find flights from Irvine to Missouri, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Irvine and Missouri flights
Browse other Irvine and Missouri flight options. Last updated on September 17, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Find a return flight route from Missouri
Find the right flight back to Irvine after your stay in Missouri
Irvine to Missouri flights
Consider these flights traveling from Irvine to Missouri.
Top 7 airlines flying from Irvine to Missouri
Discover the top 7 airlines that operate flights from Irvine to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 17, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$102 | Average$406 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$105 | Average$272 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$225 | Average$496 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$226 | Average$434 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$236 | Average$502 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$236 | Average$473 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$374 | Average$505 | FlexibilityNo cancel fee | On-time75% |