HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Missouri

Cheap flights from Irvine, CA to Missouri

LAX — STL
Nov 30 — Dec 71
Mon 11/30
Mon 12/7
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Irvine to Missouri with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Find flight deals from Irvine to Missouri

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Popular in

March

Cheapest in

January

Average price

$464
Provider with most accurate pricing for Los Angeles-Lambert-St Louis flight deals.
Search Deals
Provider most trusted by Cheapflights users for Los Angeles-Lambert-St Louis flights.
Search Deals
Highest demand for flights based on searches. 1% potential increase in price ($8 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 0% potential price decrease ($5 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in October 2026
Search Deals

Cheapflights Insights

Everything you need to know about your flight from Irvine to Missouri

What is the cheapest time of day to fly from IR9 to MO?

One of the essential ways to save on airfare from Irvine to Missouri is to remain as flexible as possible. Flights that are at noon tend to be the most expensive. A flight in the evening could potentially save you up to 13% on airfare.

What is the cheapest day to fly from Irvine to Missouri?

Travelers seeking maximum savings on their Irvine to Missouri flight should consider departing on Wednesday afternoons when fares are most often at their lowest. Sunday evenings flights should be avoided if possible as fares are typically the most expensive at this time.

Reviews of airlines servicing Missouri

Peruse reviews from past customers who have flown with Southwest,Delta, andUnited Airlines from Irvine to Missouri to help guide your decision. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
7.9
Good
4,217 reviews

Boarding

8.1

Crew

8.6

Comfort

8.0

Food

7.0

Entertainment

7.4

Overall

7.9

Reviews

1 / 20
10.0
Excellent

Courtney,Sep 2026

DEN - STL

I still think the aircraft should load from the back and window seats first for all passengers. It's so much easier and efficient to board when you do not have to worry about hitting Anyone already seated.
Southwest
7.9
Good
4,217 reviews
Southwest
7.9
Good
4,217 reviews

Boarding

8.1

Crew

8.6

Comfort

8.0

Food

7.0

Entertainment

7.4

Overall

7.9

Reviews

1 / 20
10.0
Excellent

Courtney,Sep 2026

DEN - STL

I still think the aircraft should load from the back and window seats first for all passengers. It's so much easier and efficient to board when you do not have to worry about hitting Anyone already seated.
Delta
7.8
Good
8,692 reviews
Southwest
7.9
Good
4,217 reviews

Boarding

8.1

Crew

8.6

Comfort

8.0

Food

7.0

Entertainment

7.4

Overall

7.9

Reviews

1 / 20
10.0
Excellent

Courtney,Sep 2026

DEN - STL

I still think the aircraft should load from the back and window seats first for all passengers. It's so much easier and efficient to board when you do not have to worry about hitting Anyone already seated.
United Airlines
7.3
Good
10,451 reviews
Southwest
7.9
Good
4,217 reviews

Boarding

8.1

Crew

8.6

Comfort

8.0

Food

7.0

Entertainment

7.4

Overall

7.9

Reviews

1 / 20
10.0
Excellent

Courtney,Sep 2026

DEN - STL

I still think the aircraft should load from the back and window seats first for all passengers. It's so much easier and efficient to board when you do not have to worry about hitting Anyone already seated.
American Airlines
7.0
Good
12,210 reviews
Southwest
7.9
Good
4,217 reviews

Boarding

8.1

Crew

8.6

Comfort

8.0

Food

7.0

Entertainment

7.4

Overall

7.9

Reviews

1 / 20
10.0
Excellent

Courtney,Sep 2026

DEN - STL

I still think the aircraft should load from the back and window seats first for all passengers. It's so much easier and efficient to board when you do not have to worry about hitting Anyone already seated.
Frontier
5.5
Fair
2,516 reviews
Southwest
7.9
Good
4,217 reviews

Boarding

8.1

Crew

8.6

Comfort

8.0

Food

7.0

Entertainment

7.4

Overall

7.9

Reviews

1 / 20
10.0
Excellent

Courtney,Sep 2026

DEN - STL

I still think the aircraft should load from the back and window seats first for all passengers. It's so much easier and efficient to board when you do not have to worry about hitting Anyone already seated.

Related info for your journey

  • How popular is this Irvine to Missouri flight route?

    Within the past month, 25 users have taken a look at flights from Irvine to Missouri.

  • What are the cheapest airlines to fly from Irvine to Missouri one-way?

    The cheapest airlines for a one-way flight from Irvine to Missouri are Frontier ($73), American Airlines ($136), and United Airlines ($140).

  • What are the most popular routes from Irvine to Missouri?

    Most travelers choose Los Angeles - Kansas City, Los Angeles - Lambert-St Louis or Los Angeles - Springfield-Branson when deciding on the best route from Irvine to Missouri.

  • What are the most reliable airlines from Irvine to Missouri?

    Before booking your flight to Missouri from Irvine, check out the most reliable airlines to get you to your destination on time: Qatar Airways (93%), Alaska Airlines (91%), SkyWest Airlines( 85%).

  • What are the cheapest flights from Irvine to Missouri?

    While on average a flight from Irvine to Missouri is generally $424, our data shows the cheapest flight currently is $178. When looking at the most popular route, (Los Angeles - Kansas City), you can expect to pay $149 for that flight.

  • Can I find deals for flights from Irvine to Missouri that include hotel bookings?

    Yes. In addition to deals on Irvine to Missouri flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Irvine to Missouri?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Irvine to Missouri.

  • Can I find deals for business class flights from Irvine to Missouri?

    Yes. Cheapflights offers flight deals from Irvine to Missouri by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Alternative routes for Irvine to Missouri

San Francisco to John F Kennedy Intl flights
San Francisco to Newark flights
Los Angeles to Honolulu flights
San Francisco to LaGuardia flights
Los Angeles to John F Kennedy Intl flights
Long Beach to Honolulu flights
Ontario to Honolulu flights
Los Angeles to Newark flights
Burbank to Honolulu flights
Los Angeles to Dallas/Fort Worth flights
Los Angeles to Seattle flights
Los Angeles to LaGuardia flights
San Francisco to Los Angeles flights
Ontario to Seattle flights
Los Angeles to Las Vegas flights
San Francisco to Seattle flights
San Francisco to Las Vegas flights
Los Angeles to O'Hare Intl flights
Los Angeles to Miami flights
Los Angeles to San Francisco flights
San Francisco to Dallas/Fort Worth flights
San Francisco to Ontario flights
Ontario to San Francisco flights
Ontario to Dallas/Fort Worth flights
Los Angeles to Hobby flights
Santa Ana to San Francisco flights
Los Angeles to Orlando flights
San Francisco to Santa Ana flights
Santa Ana to Dallas/Fort Worth flights
San Francisco to O'Hare Intl flights
San Jose to Los Angeles flights
Santa Ana to Las Vegas flights
Los Angeles to Denver flights
Los Angeles to Boston flights
Los Angeles to Fort Lauderdale flights
Los Angeles to George Bush Intcntl flights
Los Angeles to Atlanta flights
San Francisco to Sky Harbor Intl flights
Los Angeles to San Jose flights
Los Angeles to New Orleans flights
San Francisco to Boston flights
Ontario to John F Kennedy Intl flights
San Francisco to Miami flights
Ontario to O'Hare Intl flights
Los Angeles to Austin flights
San Francisco to Dulles Intl flights
Los Angeles to Reagan-National flights
Los Angeles to Portland flights
San Francisco to Honolulu flights
Oakland to Las Vegas flights

Top 7 airlines flying from Irvine to Missouri

AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$102Average$435FlexibilityNo cancel feeOn-timeN/A
FrontierCheapest$147Average$318FlexibilityNo cancel feeOn-time62%
JetBlueCheapest$226Average$459FlexibilityNo cancel feeOn-time62%
United AirlinesCheapest$236Average$487FlexibilityNo cancel feeOn-time69%
SouthwestCheapest$237Average$511FlexibilityNo cancel feeOn-time63%
American AirlinesCheapest$261Average$513FlexibilityNo cancel feeOn-time71%
Alaska AirlinesCheapest$374Average$581FlexibilityNo cancel feeOn-time75%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.
Site
©2026 Cheapflights