$59+ Cheap flights from Illinois to Missouri
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/4. Fares are subject to change and may not be available on all flights or dates of travel.
ORD — STL
Apr 20 — Apr 271
Round-trip
1 adult, Economy
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Cheapest flights from Illinois to MissouriExplore the most affordable flight options available from Illinois to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 21, 2026.
Explore the most affordable flight options available from Illinois to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 21, 2026.
This Booking.com deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/612:10 pm
ORD
- CGI
Nonstop1h 40m
Contour
Sat 4/119:45 am
CGI
- ORD
Nonstop1h 45m
Contour
Deal found 3/17![Contour logo]()
$123
This Contour deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Contour is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/3112:10 pm
ORD
- CGI
Nonstop1h 40m
Contour
Wed 4/19:45 am
CGI
- ORD
Nonstop1h 45m
Contour
Deal found 3/16![Contour logo]()
$139
This Booking.com deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/2412:10 pm
ORD
- CGI
Nonstop1h 40m
Contour
Sun 4/269:45 am
CGI
- ORD
Nonstop1h 45m
Contour
Deal found 3/16![Contour logo]()
$207
This Booking.com deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/312:10 pm
ORD
- CGI
Nonstop1h 40m
Contour
Fri 4/249:45 am
CGI
- ORD
Nonstop1h 45m
Contour
Deal found 3/16![Contour logo]()
$226
This Travelocity deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Travelocity is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/229:48 pm
ORD
- MCI
1 stop15h 12m
Frontier
Sat 7/251:45 pm
MCI
- ORD
1 stop7h 08m
Frontier
Deal found 3/21![Frontier logo]()
$230
This Southwest deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/87:45 am
MDW
- MCI
Nonstop1h 30m
Southwest
Wed 4/83:30 pm
MCI
- MDW
Nonstop1h 25m
Southwest
Deal found 3/18![Southwest logo]()
$231
This United Airlines deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/1412:40 pm
ORD
- MCI
Nonstop1h 45m
United Airlines
Tue 4/219:55 am
MCI
- ORD
Nonstop1h 42m
United Airlines
Deal found 3/16![United Airlines logo]()
$231
This Kiwi.com deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/158:23 pm
STL
- MCI
1 stop14h 35m
Frontier
Fri 4/1711:19 am
MCI
- STL
2 stops12h 00m
Frontier
Deal found 3/19![Frontier logo]()
$232
This KAYAK deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/1411:55 am
ORD
- STL
1 stop9h 20m
Southwest
Thu 4/165:25 am
STL
- ORD
1 stop12h 05m
Southwest
Deal found 3/18![Southwest logo]()
$234
This Kiwi.com deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/143:27 pm
ORD
- CGI
1 stop29h 08m
Multiple Airlines
Tue 4/219:45 am
CGI
- ORD
Nonstop1h 45m
Multiple Airlines
Deal found 3/17![Multiple Airlines logo]()
$235
This KAYAK deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/149:40 am
MDW
- STL
3 stops10h 20m
Southwest
Thu 4/169:40 pm
STL
- MDW
Nonstop1h 05m
Southwest
Deal found 3/18![Southwest logo]()
$235
This Frontier deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/44:21 pm
ORD
- STL
1 stop7h 04m
Frontier
Wed 4/84:59 pm
STL
- ORD
1 stop6h 37m
Frontier
Deal found 3/20![Frontier logo]()
$235
Best flights from Illinois to MissouriDiscover carefully curated flight deals from Illinois to Missouri that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 21, 2026.
Discover carefully curated flight deals from Illinois to Missouri that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 21, 2026.
This Contour deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Contour is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/1412:10 pm
ORD
- CGI
Nonstop1h 40m
Contour
Tue 4/219:45 am
CGI
- ORD
Nonstop1h 45m
Contour
Deal found 3/18![Contour logo]()
$139
This Southwest deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/35:15 am
MDW
- STL
1 stop5h 50m
Southwest
Tue 5/128:45 pm
STL
- MDW
Nonstop1h 05m
Southwest
Deal found 3/20![Southwest logo]()
$237
This United Airlines deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/2810:57 pm
ORD
- COU
Nonstop1h 33m
United Airlines
Sat 5/305:00 am
COU
- ORD
Nonstop1h 41m
United Airlines
Deal found 3/19![United Airlines logo]()
$239
This American Airlines deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/187:56 pm
ORD
- COU
Nonstop1h 34m
American Airlines
Sat 4/2510:16 am
COU
- ORD
Nonstop1h 31m
American Airlines
Deal found 3/21![American Airlines logo]()
$239
This Kiwi.com deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/144:36 pm
ORD
- CGI
2 stops27h 59m
Multiple Airlines
Tue 4/219:45 am
CGI
- ORD
Nonstop1h 45m
Multiple Airlines
Deal found 3/17![Multiple Airlines logo]()
$241
This Delta deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/88:55 am
ORD
- STL
1 stop4h 22m
Delta
Tue 6/92:18 pm
STL
- ORD
1 stop4h 23m
Delta
Deal found 3/16![Delta logo]()
$245
This Contour deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Contour is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/3112:10 pm
ORD
- CGI
Nonstop1h 40m
Contour
Wed 4/19:45 am
CGI
- ORD
Nonstop1h 45m
Contour
Deal found 3/16![Contour logo]()
$139
This United Airlines deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/148:18 pm
ORD
- COU
Nonstop1h 43m
United Airlines
Tue 4/218:00 am
COU
- ORD
Nonstop1h 30m
United Airlines
Deal found 3/17![United Airlines logo]()
$239
This Southwest deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/304:15 pm
ORD
- STL
1 stop8h 00m
Southwest
Sat 5/166:10 am
STL
- ORD
2 stops8h 10m
Southwest
Deal found 3/19![Southwest logo]()
$246
This American Airlines deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/104:40 pm
ORD
- COU
1 stop6h 13m
American Airlines
Sun 4/126:00 am
COU
- ORD
Nonstop1h 43m
American Airlines
Deal found 3/19![American Airlines logo]()
$248
This United Airlines deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/1010:50 pm
ORD
- COU
Nonstop1h 43m
United Airlines
Mon 4/138:00 am
COU
- ORD
Nonstop1h 30m
United Airlines
Deal found 3/19![United Airlines logo]()
$239
This Delta deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/158:52 am
ORD
- STL
2 stops7h 58m
Delta
Mon 4/2012:23 pm
STL
- ORD
2 stops8h 17m
Delta
Deal found 3/19![Delta logo]()
$267
This CheapOair deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/1212:10 pm
ORD
- CGI
Nonstop1h 40m
Contour
Tue 5/199:45 am
CGI
- ORD
Nonstop1h 45m
Contour
Deal found 3/20![Contour logo]()
$243
This Southwest deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/293:25 pm
MDW
- STL
1 stop5h 25m
Southwest
Tue 6/21:15 pm
STL
- MDW
2 stops6h 20m
Southwest
Deal found 3/19![Southwest logo]()
$248
This American Airlines deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/238:00 am
ORD
- SGF
Nonstop1h 51m
American Airlines
Fri 5/110:21 am
SGF
- ORD
Nonstop1h 48m
American Airlines
Deal found 3/21![American Airlines logo]()
$249
This United Airlines deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/189:15 am
ORD
- COU
Nonstop1h 40m
United Airlines
Sat 4/258:00 am
COU
- ORD
Nonstop1h 30m
United Airlines
Deal found 3/21![United Airlines logo]()
$239
This Delta deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/268:15 am
ORD
- SGF
1 stop6h 30m
Delta
Sun 8/306:00 am
SGF
- ORD
1 stop6h 08m
Delta
Deal found 3/17![Delta logo]()
$269
This American Airlines deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/146:04 am
ORD
- COU
1 stop5h 31m
American Airlines
Tue 4/215:21 pm
COU
- ORD
1 stop6h 27m
American Airlines
Deal found 3/17![American Airlines logo]()
$258
This Southwest deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/139:30 pm
MDW
- STL
Nonstop1h 15m
Southwest
Fri 4/171:45 pm
STL
- MDW
Nonstop1h 10m
Southwest
Deal found 3/18![Southwest logo]()
$264
This Delta deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/3012:10 pm
ORD
- SGF
1 stop6h 00m
Delta
Sun 8/26:45 pm
SGF
- ORD
1 stop5h 10m
Delta
Deal found 3/18![Delta logo]()
$269
This United Airlines deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/268:45 am
ORD
- SGF
Nonstop1h 58m
United Airlines
Sun 8/306:35 pm
SGF
- ORD
Nonstop1h 55m
United Airlines
Deal found 3/17![United Airlines logo]()
$249
This Booking.com deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/2411:50 am
ORD
- CGI
Nonstop1h 40m
Contour
Sat 3/289:25 am
CGI
- ORD
Nonstop1h 45m
Contour
Deal found 3/16![Contour logo]()
$289
This Southwest deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/148:15 am
MDW
- STL
Nonstop1h 15m
Southwest
Fri 4/171:45 pm
STL
- MDW
Nonstop1h 10m
Southwest
Deal found 3/16![Southwest logo]()
$264
This American Airlines deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/148:55 pm
ORD
- STL
Nonstop1h 24m
American Airlines
Fri 4/172:33 pm
STL
- ORD
Nonstop1h 28m
American Airlines
Deal found 3/16![American Airlines logo]()
$264
This Delta deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/1410:41 am
MDW
- SGF
1 stop4h 33m
Delta
Tue 4/213:59 pm
SGF
- MDW
1 stop6h 29m
Delta
Deal found 3/17![Delta logo]()
$269
This United Airlines deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/28:02 pm
ORD
- SGF
Nonstop2h 00m
United Airlines
Wed 5/66:22 pm
SGF
- ORD
Nonstop1h 43m
United Airlines
Deal found 3/19![United Airlines logo]()
$249
This Contour deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Contour is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/312:10 pm
ORD
- CGI
Nonstop1h 40m
Contour
Tue 4/79:45 am
CGI
- ORD
Nonstop1h 45m
Contour
Deal found 3/19![Contour logo]()
$293
This Delta deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/265:25 pm
MDW
- SGF
1 stop5h 04m
Delta
Sun 8/306:00 am
SGF
- MDW
1 stop5h 54m
Delta
Deal found 3/17![Delta logo]()
$269
This Southwest deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/19:30 pm
MDW
- MCI
Nonstop1h 30m
Southwest
Thu 6/41:45 pm
MCI
- MDW
1 stop5h 50m
Southwest
Deal found 3/19![Southwest logo]()
$275
This United Airlines deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/98:08 pm
ORD
- COU
Nonstop1h 51m
United Airlines
Sun 7/128:00 am
COU
- ORD
Nonstop1h 40m
United Airlines
Deal found 3/16![United Airlines logo]()
$253
Last-minute flights from Illinois to MissouriDiscover last-minute flight deals from Illinois to Missouri. Data last updated March 21, 2026 and is based on user searches.
Discover last-minute flight deals from Illinois to Missouri. Data last updated March 21, 2026 and is based on user searches.
This Contour deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Contour is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/3112:10 pm
ORD
- CGI
Nonstop1h 40m
Contour
Wed 4/19:45 am
CGI
- ORD
Nonstop1h 45m
Contour
Deal found 3/16![Contour logo]()
$139
This Booking.com deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/312:10 pm
ORD
- CGI
Nonstop1h 40m
Contour
Sun 4/59:45 am
CGI
- ORD
Nonstop1h 45m
Contour
Deal found 3/16![Contour logo]()
$226
This Booking.com deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/612:10 pm
ORD
- CGI
Nonstop1h 40m
Contour
Sat 4/119:45 am
CGI
- ORD
Nonstop1h 45m
Contour
Deal found 3/17![Contour logo]()
$123
This Southwest deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/87:45 am
MDW
- MCI
Nonstop1h 30m
Southwest
Wed 4/83:30 pm
MCI
- MDW
Nonstop1h 25m
Southwest
Deal found 3/18![Southwest logo]()
$231
This United Airlines deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/1412:40 pm
ORD
- MCI
Nonstop1h 45m
United Airlines
Tue 4/219:55 am
MCI
- ORD
Nonstop1h 42m
United Airlines
Deal found 3/16![United Airlines logo]()
$231
This KAYAK deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/1411:55 am
ORD
- STL
1 stop9h 20m
Southwest
Thu 4/165:25 am
STL
- ORD
1 stop12h 05m
Southwest
Deal found 3/18![Southwest logo]()
$234
This Kiwi.com deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/143:27 pm
ORD
- CGI
1 stop29h 08m
Multiple Airlines
Tue 4/219:45 am
CGI
- ORD
Nonstop1h 45m
Multiple Airlines
Deal found 3/17![Multiple Airlines logo]()
$235
This KAYAK deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/149:40 am
MDW
- STL
3 stops10h 20m
Southwest
Thu 4/169:40 pm
STL
- MDW
Nonstop1h 05m
Southwest
Deal found 3/18![Southwest logo]()
$235
This Kiwi.com deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/158:23 pm
STL
- MCI
1 stop14h 35m
Frontier
Fri 4/1711:19 am
MCI
- STL
2 stops12h 00m
Frontier
Deal found 3/19![Frontier logo]()
$232
This Kiwi.com deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/2012:10 pm
ORD
- CGI
Nonstop1h 40m
Contour
Tue 4/219:45 am
CGI
- ORD
Nonstop1h 45m
Contour
Deal found 3/16![Contour logo]()
$137
This Kiwi.com deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/214:03 pm
ORD
- CGI
1 stop28h 32m
Multiple Airlines
Fri 4/249:45 am
CGI
- ORD
Nonstop1h 45m
Multiple Airlines
Deal found 3/16![Multiple Airlines logo]()
$207
This Kiwi.com deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/2312:10 pm
ORD
- CGI
Nonstop1h 40m
Contour
Fri 4/249:45 am
CGI
- ORD
Nonstop1h 45m
Contour
Deal found 3/16![Contour logo]()
$192
One-way flights from Illinois to MissouriSearch for one-way flight options from Illinois to Missouri. Find affordable one-way fares based on user searches. Data last updated March 21, 2026.
Search for one-way flight options from Illinois to Missouri. Find affordable one-way fares based on user searches. Data last updated March 21, 2026.
This Booking.com deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/412:10 pm
ORD
- CGI
Nonstop1h 40m
Contour
Deal found 3/20![Contour logo]()
$59
This Southwest deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/158:15 am
MDW
- STL
Nonstop1h 15m
Southwest
Deal found 3/20![Southwest logo]()
$59
This American Airlines deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/1410:25 am
ORD
- STL
Nonstop1h 22m
American Airlines
Deal found 3/20![American Airlines logo]()
$59
This Southwest deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/2111:55 am
ORD
- STL
1 stop6h 00m
Southwest
Deal found 3/16![Southwest logo]()
$69
This Frontier deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/114:21 pm
ORD
- STL
1 stop7h 04m
Frontier
Deal found 3/21![Frontier logo]()
$70
This Southwest deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/152:40 pm
ORD
- STL
1 stop7h 20m
Southwest
Deal found 3/20![Southwest logo]()
$74
This Expedia deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/105:05 pm
ORD
- STL
1 stop6h 53m
Frontier
Deal found 3/21![Frontier logo]()
$75
This Kiwi.com deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/216:10 am
MDW
- STL
1 stop24h 40m
Frontier
Deal found 3/20![Frontier logo]()
$78
This Kiwi.com deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/216:08 pm
ORD
- STL
1 stop12h 42m
Frontier
Deal found 3/19![Frontier logo]()
$78
This Delta deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/209:22 am
MDW
- STL
1 stop3h 48m
Delta
Deal found 3/20![Delta logo]()
$79
This Delta deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/148:15 am
ORD
- STL
1 stop7h 17m
Delta
Deal found 3/17![Delta logo]()
$79
This Delta deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/159:27 am
MDW
- STL
2 stops7h 23m
Delta
Deal found 3/20![Delta logo]()
$84
Find flight deals from Illinois to Missouri
Keep the following information in mind while searching for Illinois to Missouri flight deals. Data was last updated March 21, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $123 (Booking.com) |
One-way from | $59 (Booking.com) |
Popular in | January |
Cheapest in | December |
Average price | $488 |
Good round-trip deal | $61 or less |
Good one-way deal | $64 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Illinois to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 21, 2026.
Use the filters below to find and compare flights from Illinois to Missouri that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
ChicagoCape Girardeau
ORD - CGI
ORDCGI
Chicago O'Hare Intl
Tue 4/14
12:10 pm-1:50 pm
Nonstop1h 40m
Cape Girardeau
Tue 4/21
9:45 am-11:30 am
Nonstop1h 45m
$139
ChicagoCape Girardeau
ORD - CGI
ORDCGI
Chicago O'Hare Intl
Tue 3/31
12:10 pm-1:50 pm
Nonstop1h 40m
Cape Girardeau
Wed 4/1
9:45 am-11:30 am
Nonstop1h 45m
$139
ChicagoSt. Louis
MDW - STL
MDWSTL
Chicago Midway
Sun 5/3
5:15 am-11:05 am
1 stop5h 50m
Lambert-St Louis
Tue 5/12
8:45 pm-9:50 pm
Nonstop1h 05m
$237
ChicagoColumbia
ORD - COU
ORDCOU
Chicago O'Hare Intl
Thu 5/28
10:57 pm-12:30 am
Nonstop1h 33m
Columbia Regional
Sat 5/30
5:00 am-6:41 am
Nonstop1h 41m
$239
ChicagoColumbia
ORD - COU
ORDCOU
Chicago O'Hare Intl
Sat 4/18
7:56 pm-9:30 pm
Nonstop1h 34m
Columbia Regional
Sat 4/25
10:16 am-11:47 am
Nonstop1h 31m
$239
ChicagoColumbia
ORD - COU
ORDCOU
Chicago O'Hare Intl
Tue 4/14
8:18 pm-10:01 pm
Nonstop1h 43m
Columbia Regional
Tue 4/21
8:00 am-9:30 am
Nonstop1h 30m
$239
ChicagoColumbia
ORD - COU
ORDCOU
Chicago O'Hare Intl
Fri 4/10
10:50 pm-12:33 am
Nonstop1h 43m
Columbia Regional
Mon 4/13
8:00 am-9:30 am
Nonstop1h 30m
$239
ChicagoColumbia
ORD - COU
ORDCOU
Chicago O'Hare Intl
Sat 4/18
9:15 am-10:55 am
Nonstop1h 40m
Columbia Regional
Sat 4/25
8:00 am-9:30 am
Nonstop1h 30m
$239
ChicagoCape Girardeau
ORD - CGI
ORDCGI
Chicago O'Hare Intl
Tue 4/14
4:36 pm-8:35 pm
2 stops27h 59m
Cape Girardeau
Tue 4/21
9:45 am-11:30 am
Nonstop1h 45m
$241
ChicagoCape Girardeau
ORD - CGI
ORDCGI
Chicago O'Hare Intl
Tue 5/12
12:10 pm-1:50 pm
Nonstop1h 40m
Cape Girardeau
Tue 5/19
9:45 am-11:30 am
Nonstop1h 45m
$243
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from Illinois to Missouri
Have a flexible travel schedule? Discover the best time to fly to Missouri from Illinois with our price prediction graph.
ORD-CGI
MDW-STL
ORD-COU
ORD-STL
ORD-SGF
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Illinois to Missouri
USIL-USMO
ORD-CGI
MDW-STL
ORD-COU
ORD-STL
What is the cheapest month to book a flight from Illinois to Missouri?
Currently, August is the cheapest month in which you can book a flight from Illinois to Missouri (average of $77). Flying from Illinois to Missouri in June is currently the most expensive (average of $143). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from IL to MO?
Find hourly flight availability from Illinois to Missouri. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated March 21, 2026.
One of the essential ways to save on airfare from Illinois to Missouri is to remain as flexible as possible. Flights that are in the evening tend to be the most expensive. A flight in the morning could potentially save you up to 19% on airfare.
What is the cheapest day to fly from Illinois to Missouri?
Use this chart to determine the cheapest time to fly round-trip from Illinois to Missouri. Price data was last updated on March 14, 2026.
Travelers seeking maximum savings on their Illinois to Missouri flight should consider departing on Friday afternoons when fares are most often at their lowest. Saturday evenings flights should be avoided if possible as fares are typically the most expensive at this time.
Weekly flight availability from Illinois to Missouri
Explore weekly flight availability from Illinois to Missouri. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated March 21, 2026.
The most flights from USIL to USMO are scheduled on a Wednesday (72 on average). You will have fewer flight options on Tuesday, which is when the least amount of flights are scheduled (37 on average).
Reviews of airlines servicing Missouri
Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated March 21, 2026.
Read reviews from past customers who have flown Southwest,Contour, andUnited Airlines from Illinois to Missouri. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Boarding
8.1
Comfort
8.0
Overall
8.0
Food
7.0
Crew
8.6
Entertainment
7.5
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Boarding
8.1
Comfort
8.0
Overall
8.0
Food
7.0
Crew
8.6
Entertainment
7.5
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Boarding
8.1
Comfort
8.0
Overall
8.0
Food
7.0
Crew
8.6
Entertainment
7.5
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Boarding
8.1
Comfort
8.0
Overall
8.0
Food
7.0
Crew
8.6
Entertainment
7.5
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Boarding
8.1
Comfort
8.0
Overall
8.0
Food
7.0
Crew
8.6
Entertainment
7.5
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Boarding
8.1
Comfort
8.0
Overall
8.0
Food
7.0
Crew
8.6
Entertainment
7.5
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Related info for your journey
Find useful and relevant information for your journey from Illinois to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Illinois to Missouri
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Missouri by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Illinois to Missouri by cabin class
Find flights from Illinois to Missouri, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Illinois and Missouri flights
Browse other Illinois and Missouri flight options. Last updated on March 21, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Find a return flight route from Missouri
Find the right flight back to Illinois after your stay in Missouri
Illinois to Missouri flights
Consider these flights traveling from Illinois to Missouri.
Top 5 airlines flying from Illinois to Missouri
Discover the top 5 airlines that operate flights from Illinois to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 21, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$77 | Average$359 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$104 | Average$168 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$117 | Average$380 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$144 | Average$347 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$156 | Average$227 | FlexibilityNo cancel fee | On-timeN/A |