$40+ Cheap flights from Illinois to Missouri
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/4. Fares are subject to change and may not be available on all flights or dates of travel.
ORD — STL
Mar 5 — Mar 121
1 adult, Economy
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Find cheap flights from Illinois to Missouri with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Cheapest flights from Illinois to MissouriExplore the most affordable flight options available from Illinois to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 3, 2026.
Explore the most affordable flight options available from Illinois to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 3, 2026.
This United Airlines deal was found by Cheapflights users on 1/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/287:40 pm
ORD
- STL
Nonstop1h 25m
United Airlines
Sat 5/26:49 pm
STL
- ORD
Nonstop1h 31m
United Airlines
Deal found 1/31![United Airlines logo]()
$91
This United Airlines deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/147:40 pm
ORD
- STL
Nonstop1h 28m
United Airlines
Tue 4/219:10 am
STL
- ORD
Nonstop1h 29m
United Airlines
Deal found 2/3![United Airlines logo]()
$117
This United Airlines deal was found by Cheapflights users on 1/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/287:40 pm
ORD
- STL
Nonstop1h 25m
United Airlines
Wed 5/69:00 am
STL
- ORD
Nonstop1h 24m
United Airlines
Deal found 1/31![United Airlines logo]()
$131
This Southwest deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/142:40 pm
ORD
- STL
1 stop4h 40m
Southwest
Tue 4/215:45 am
STL
- ORD
1 stop5h 25m
Southwest
Deal found 2/1![Southwest logo]()
$137
This Kiwi.com deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/258:30 am
ORD
- STL
1 stop13h 57m
Frontier
Fri 2/278:22 pm
STL
- ORD
1 stop14h 29m
Frontier
Deal found 2/1![Frontier logo]()
$138
This Kiwi.com deal was found by Cheapflights users on 1/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/23:50 pm
ORD
- STL
1 stop30h 37m
Frontier
Mon 3/92:09 pm
STL
- ORD
1 stop18h 14m
Frontier
Deal found 1/31![Frontier logo]()
$144
This Kiwi.com deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/204:42 pm
ORD
- STL
1 stop14h 09m
Frontier
Mon 2/238:22 pm
STL
- ORD
1 stop20h 30m
Frontier
Deal found 2/2![Frontier logo]()
$146
This Kiwi.com deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/206:48 pm
MDW
- STL
1 stop12h 03m
Frontier
Mon 2/238:22 pm
STL
- MDW
1 stop22h 45m
Frontier
Deal found 2/2![Frontier logo]()
$147
This Kiwi.com deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/194:42 pm
ORD
- STL
1 stop14h 09m
Frontier
Fri 2/208:20 pm
STL
- ORD
1 stop14h 26m
Frontier
Deal found 2/2![Frontier logo]()
$151
This Kiwi.com deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/26:51 pm
ORD
- STL
2 stops36h 00m
Multiple Airlines
Mon 3/92:09 pm
STL
- ORD
1 stop18h 14m
Multiple Airlines
Deal found 2/1![Multiple Airlines logo]()
$156
This Southwest deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/186:30 pm
MDW
- STL
Nonstop1h 15m
Southwest
Mon 4/205:40 am
STL
- MDW
Nonstop1h 10m
Southwest
Deal found 2/1![Southwest logo]()
$157
This Delta deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/148:52 am
ORD
- STL
1 stop4h 13m
Delta
Tue 4/2111:43 am
STL
- ORD
1 stop4h 59m
Delta
Deal found 2/3![Delta logo]()
$157
Best flights from Illinois to MissouriDiscover carefully curated flight deals from Illinois to Missouri that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated February 3, 2026.
Discover carefully curated flight deals from Illinois to Missouri that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated February 3, 2026.
This United Airlines deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/147:40 pm
ORD
- STL
Nonstop1h 28m
United Airlines
Tue 4/219:10 am
STL
- ORD
Nonstop1h 29m
United Airlines
Deal found 2/3![United Airlines logo]()
$117
This Kiwi.com deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/204:42 pm
ORD
- STL
1 stop14h 09m
Frontier
Mon 2/238:22 pm
STL
- ORD
1 stop20h 30m
Frontier
Deal found 2/2![Frontier logo]()
$146
This Delta deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/148:52 am
ORD
- STL
1 stop4h 13m
Delta
Tue 4/2111:43 am
STL
- ORD
1 stop4h 59m
Delta
Deal found 2/3![Delta logo]()
$157
This Southwest deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/1810:30 am
MDW
- STL
1 stop5h 45m
Southwest
Mon 4/209:40 pm
STL
- MDW
Nonstop1h 05m
Southwest
Deal found 2/1![Southwest logo]()
$167
This American Airlines deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/34:30 pm
ORD
- COU
Nonstop1h 30m
American Airlines
Sat 4/46:50 pm
COU
- ORD
Nonstop1h 35m
American Airlines
Deal found 2/1![American Airlines logo]()
$179
This Kiwi.com deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/173:49 pm
STL
- MCI
1 stop23h 40m
Multiple Airlines
Sun 2/2210:14 am
MCI
- STL
1 stop20h 37m
Multiple Airlines
Deal found 2/1![Multiple Airlines logo]()
$217
This United Airlines deal was found by Cheapflights users on 1/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/287:40 pm
ORD
- STL
Nonstop1h 25m
United Airlines
Wed 5/69:00 am
STL
- ORD
Nonstop1h 24m
United Airlines
Deal found 1/31![United Airlines logo]()
$131
This American Airlines deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/56:50 pm
ORD
- COU
Nonstop1h 29m
American Airlines
Sun 3/86:30 pm
COU
- ORD
Nonstop1h 35m
American Airlines
Deal found 2/1![American Airlines logo]()
$179
This Delta deal was found by Cheapflights users on 1/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/110:45 am
MDW
- STL
1 stop7h 08m
Delta
Wed 5/66:20 am
STL
- MDW
1 stop7h 12m
Delta
Deal found 1/31![Delta logo]()
$191
This Kiwi.com deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/66:05 am
MDW
- STL
1 stop5h 44m
Frontier
Sun 3/87:52 am
STL
- MDW
1 stop29h 16m
Frontier
Deal found 2/1![Frontier logo]()
$191
This United Airlines deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/239:00 am
ORD
- COU
Nonstop1h 33m
United Airlines
Sun 3/111:15 am
COU
- ORD
Nonstop1h 30m
United Airlines
Deal found 2/2![United Airlines logo]()
$179
This American Airlines deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/18:18 am
ORD
- SGF
Nonstop1h 50m
American Airlines
Sun 3/87:36 am
SGF
- ORD
Nonstop1h 51m
American Airlines
Deal found 2/1![American Airlines logo]()
$189
This Delta deal was found by Cheapflights users on 1/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/19:35 am
MDW
- STL
1 stop3h 23m
Delta
Sat 5/212:23 pm
STL
- MDW
1 stop6h 13m
Delta
Deal found 1/31![Delta logo]()
$191
This United Airlines deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/139:00 am
ORD
- COU
Nonstop1h 33m
United Airlines
Sun 3/1511:15 am
COU
- ORD
Nonstop1h 30m
United Airlines
Deal found 2/2![United Airlines logo]()
$179
This Kiwi.com deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/23:49 pm
STL
- MCI
1 stop23h 40m
Multiple Airlines
Mon 3/911:26 am
MCI
- STL
2 stops35h 53m
Multiple Airlines
Deal found 2/2![Multiple Airlines logo]()
$218
This Southwest deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/36:10 am
MDW
- MCI
1 stop5h 15m
Southwest
Tue 3/101:50 pm
MCI
- MDW
Nonstop1h 20m
Southwest
Deal found 2/2![Southwest logo]()
$221
This American Airlines deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/318:03 am
ORD
- SGF
Nonstop1h 50m
American Airlines
Sun 4/56:00 pm
SGF
- ORD
Nonstop1h 49m
American Airlines
Deal found 2/2![American Airlines logo]()
$189
This Delta deal was found by Cheapflights users on 1/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/19:35 am
MDW
- STL
1 stop3h 23m
Delta
Thu 4/306:20 am
STL
- MDW
1 stop7h 12m
Delta
Deal found 1/31![Delta logo]()
$191
This United Airlines deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/59:00 am
ORD
- COU
Nonstop1h 33m
United Airlines
Sat 3/72:41 pm
COU
- ORD
Nonstop1h 28m
United Airlines
Deal found 2/1![United Airlines logo]()
$179
This Travelocity deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Travelocity is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/136:00 am
MDW
- MCI
1 stop9h 36m
Frontier
Mon 4/2011:13 am
MCI
- MDW
1 stop8h 18m
Frontier
Deal found 2/2![Frontier logo]()
$221
This Southwest deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/1711:40 am
MDW
- STL
Nonstop1h 15m
Southwest
Sat 4/182:05 pm
STL
- MDW
Nonstop1h 10m
Southwest
Deal found 2/3![Southwest logo]()
$223
This Delta deal was found by Cheapflights users on 1/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/17:20 am
ORD
- STL
1 stop9h 47m
Delta
Wed 5/69:59 am
STL
- ORD
1 stop6h 43m
Delta
Deal found 1/31![Delta logo]()
$191
This United Airlines deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/99:15 am
ORD
- COU
Nonstop1h 40m
United Airlines
Sat 4/1111:30 am
COU
- ORD
Nonstop1h 30m
United Airlines
Deal found 2/1![United Airlines logo]()
$179
This Kiwi.com deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/218:17 pm
STL
- MCI
1 stop13h 12m
Multiple Airlines
Sun 2/224:24 pm
MCI
- STL
2 stops20h 45m
Multiple Airlines
Deal found 2/1![Multiple Airlines logo]()
$240
This Southwest deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/41:15 pm
MDW
- MCI
Nonstop1h 30m
Southwest
Wed 3/45:25 pm
MCI
- MDW
Nonstop1h 25m
Southwest
Deal found 2/1![Southwest logo]()
$231
This United Airlines deal was found by Cheapflights users on 1/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/268:20 pm
ORD
- STL
Nonstop1h 30m
United Airlines
Sat 5/26:49 pm
STL
- ORD
Nonstop1h 31m
United Airlines
Deal found 1/31![United Airlines logo]()
$183
This American Airlines deal was found by Cheapflights users on 1/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/134:35 pm
ORD
- COU
Nonstop1h 30m
American Airlines
Tue 4/74:29 pm
COU
- ORD
Nonstop1h 39m
American Airlines
Deal found 1/31![American Airlines logo]()
$224
This Kiwi.com deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/13:49 pm
STL
- MCI
1 stop23h 40m
Multiple Airlines
Sun 3/811:26 am
MCI
- STL
2 stops25h 53m
Multiple Airlines
Deal found 2/1![Multiple Airlines logo]()
$252
This Delta deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/239:48 am
ORD
- SGF
1 stop6h 59m
Delta
Tue 3/35:32 pm
SGF
- ORD
1 stop6h 24m
Delta
Deal found 2/2![Delta logo]()
$209
This Southwest deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/246:00 am
MDW
- MCI
1 stop4h 20m
Southwest
Sat 2/287:35 am
MCI
- MDW
2 stops5h 55m
Southwest
Deal found 2/1![Southwest logo]()
$236
Last-minute flights from Illinois to MissouriDiscover last-minute flight deals from Illinois to Missouri. Data last updated February 3, 2026 and is based on user searches.
Discover last-minute flight deals from Illinois to Missouri. Data last updated February 3, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/194:42 pm
ORD
- STL
1 stop14h 09m
Frontier
Fri 2/208:20 pm
STL
- ORD
1 stop14h 26m
Frontier
Deal found 2/2![Frontier logo]()
$151
This Kiwi.com deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/204:42 pm
ORD
- STL
1 stop14h 09m
Frontier
Mon 2/238:22 pm
STL
- ORD
1 stop20h 30m
Frontier
Deal found 2/2![Frontier logo]()
$146
This Kiwi.com deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/206:48 pm
MDW
- STL
1 stop12h 03m
Frontier
Mon 2/238:22 pm
STL
- MDW
1 stop22h 45m
Frontier
Deal found 2/2![Frontier logo]()
$147
This United Airlines deal was found by Cheapflights users on 1/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/219:05 am
ORD
- STL
Nonstop1h 31m
United Airlines
Wed 2/257:41 am
STL
- ORD
Nonstop1h 29m
United Airlines
Deal found 1/31![United Airlines logo]()
$173
This Kiwi.com deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/258:30 am
ORD
- STL
1 stop13h 57m
Frontier
Fri 2/278:22 pm
STL
- ORD
1 stop14h 29m
Frontier
Deal found 2/1![Frontier logo]()
$138
This Kiwi.com deal was found by Cheapflights users on 1/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/23:50 pm
ORD
- STL
1 stop30h 37m
Frontier
Mon 3/92:09 pm
STL
- ORD
1 stop18h 14m
Frontier
Deal found 1/31![Frontier logo]()
$144
This Kiwi.com deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/26:51 pm
ORD
- STL
2 stops36h 00m
Multiple Airlines
Mon 3/92:09 pm
STL
- ORD
1 stop18h 14m
Multiple Airlines
Deal found 2/1![Multiple Airlines logo]()
$156
This United Airlines deal was found by Cheapflights users on 1/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/287:40 pm
ORD
- STL
Nonstop1h 25m
United Airlines
Sat 5/26:49 pm
STL
- ORD
Nonstop1h 31m
United Airlines
Deal found 1/31![United Airlines logo]()
$91
This United Airlines deal was found by Cheapflights users on 1/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/287:40 pm
ORD
- STL
Nonstop1h 25m
United Airlines
Wed 5/69:00 am
STL
- ORD
Nonstop1h 24m
United Airlines
Deal found 1/31![United Airlines logo]()
$131
This United Airlines deal was found by Cheapflights users on 1/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/288:12 pm
ORD
- STL
Nonstop1h 30m
United Airlines
Mon 5/47:45 am
STL
- ORD
Nonstop1h 27m
United Airlines
Deal found 1/31![United Airlines logo]()
$161
This United Airlines deal was found by Cheapflights users on 1/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/317:40 pm
ORD
- STL
Nonstop1h 28m
United Airlines
Sat 5/27:45 am
STL
- ORD
Nonstop1h 27m
United Airlines
Deal found 1/31![United Airlines logo]()
$168
This American Airlines deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/318:11 am
ORD
- STL
1 stop5h 05m
American Airlines
Sat 4/48:00 am
STL
- ORD
Nonstop1h 31m
American Airlines
Deal found 2/1![American Airlines logo]()
$178
One-way flights from Illinois to MissouriSearch for one-way flight options from Illinois to Missouri. Find affordable one-way fares based on user searches. Data last updated February 3, 2026.
Search for one-way flight options from Illinois to Missouri. Find affordable one-way fares based on user searches. Data last updated February 3, 2026.
This Southwest deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/45:40 pm
MDW
- STL
Nonstop1h 15m
Southwest
Deal found 2/1![Southwest logo]()
$40
This United Airlines deal was found by Cheapflights users on 1/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/28:20 pm
ORD
- STL
Nonstop1h 32m
United Airlines
Deal found 1/31![United Airlines logo]()
$46
This Southwest deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/113:05 pm
MDW
- STL
1 stop5h 15m
Southwest
Deal found 2/1![Southwest logo]()
$50
This Southwest deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/14:45 pm
MDW
- STL
Nonstop1h 15m
Southwest
Deal found 2/3![Southwest logo]()
$59
This United Airlines deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/78:15 pm
ORD
- STL
Nonstop1h 32m
United Airlines
Deal found 2/3![United Airlines logo]()
$59
This Kiwi.com deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/311:56 am
ORD
- STL
1 stop18h 55m
Frontier
Deal found 2/2![Frontier logo]()
$61
This Frontier deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/282:51 pm
STL
- MCI
1 stop4h 55m
Frontier
Deal found 2/2![Frontier logo]()
$64
This Kiwi.com deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/176:00 am
MDW
- STL
1 stop24h 51m
Frontier
Deal found 2/2![Frontier logo]()
$65
This Southwest deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/147:55 am
MDW
- MCI
Nonstop1h 35m
Southwest
Deal found 2/2![Southwest logo]()
$67
This Kiwi.com deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/277:53 pm
MDW
- STL
1 stop10h 58m
Frontier
Deal found 2/3![Frontier logo]()
$67
This Southwest deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/12:40 pm
ORD
- STL
1 stop5h 15m
Southwest
Deal found 2/3![Southwest logo]()
$69
This Mytrip deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/48:16 pm
ORD
- MCI
1 stop14h 14m
Spirit Airlines
Deal found 2/2![Spirit Airlines logo]()
$70
Find flight deals from Illinois to Missouri
Keep the following information in mind while searching for Illinois to Missouri flight deals. Data was last updated February 3, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $91 (United Airlines) |
One-way from | $40 (Southwest) |
Popular in | January |
Cheapest in | December |
Average price | $317 |
Good round-trip deal | $61 or less |
Good one-way deal | $85 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Illinois to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 3, 2026.
Use the filters below to find and compare flights from Illinois to Missouri that are best for you.
Fly from
Illinois
Fly to
Missouri
Route
Depart
Return
Price
ChicagoSt. Louis
ORD - STL
ORDSTL
Chicago O'Hare Intl
Tue 4/14
7:40 pm-9:08 pm
Nonstop1h 28m
Lambert-St Louis
Tue 4/21
9:10 am-10:39 am
Nonstop1h 29m
$117
ChicagoSt. Louis
ORD - STL
ORDSTL
Chicago O'Hare Intl
Sat 3/28
7:40 pm-9:05 pm
Nonstop1h 25m
Lambert-St Louis
Wed 5/6
9:00 am-10:24 am
Nonstop1h 24m
$131
ChicagoSt. Louis
ORD - STL
ORDSTL
Chicago O'Hare Intl
Fri 2/20
4:42 pm-6:51 am
1 stop14h 09m
Lambert-St Louis
Mon 2/23
8:22 pm-4:52 pm
1 stop20h 30m
$146
ChicagoSt. Louis
ORD - STL
ORDSTL
Chicago O'Hare Intl
Tue 4/14
8:52 am-1:05 pm
1 stop4h 13m
Lambert-St Louis
Tue 4/21
11:43 am-4:42 pm
1 stop4h 59m
$157
ChicagoSt. Louis
MDW - STL
MDWSTL
Chicago Midway
Sat 4/18
10:30 am-4:15 pm
1 stop5h 45m
Lambert-St Louis
Mon 4/20
9:40 pm-10:45 pm
Nonstop1h 05m
$167
ChicagoColumbia
ORD - COU
ORDCOU
Chicago O'Hare Intl
Fri 4/3
4:30 pm-6:00 pm
Nonstop1h 30m
Columbia Regional
Sat 4/4
6:50 pm-8:25 pm
Nonstop1h 35m
$179
ChicagoColumbia
ORD - COU
ORDCOU
Chicago O'Hare Intl
Thu 3/5
6:50 pm-8:19 pm
Nonstop1h 29m
Columbia Regional
Sun 3/8
6:30 pm-8:05 pm
Nonstop1h 35m
$179
ChicagoColumbia
ORD - COU
ORDCOU
Chicago O'Hare Intl
Mon 2/23
9:00 am-10:33 am
Nonstop1h 33m
Columbia Regional
Sun 3/1
11:15 am-12:45 pm
Nonstop1h 30m
$179
ChicagoColumbia
ORD - COU
ORDCOU
Chicago O'Hare Intl
Fri 3/13
9:00 am-10:33 am
Nonstop1h 33m
Columbia Regional
Sun 3/15
11:15 am-12:45 pm
Nonstop1h 30m
$179
ChicagoColumbia
ORD - COU
ORDCOU
Chicago O'Hare Intl
Thu 3/5
9:00 am-10:33 am
Nonstop1h 33m
Columbia Regional
Sat 3/7
2:41 pm-4:09 pm
Nonstop1h 28m
$179
Showing 1-10 of 60 results
Best time to book a flight from Illinois to Missouri
Have a flexible travel schedule? Discover the best time to fly to Missouri from Illinois with our price prediction graph.
ORD-STL
MDW-STL
ORD-COU
STL-MCI
ORD-SGF
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Illinois to Missouri
USIL-USMO
ORD-STL
MDW-STL
ORD-COU
STL-MCI
What is the cheapest month to book a flight from Illinois to Missouri?
Currently, August is the cheapest month in which you can book a flight from Illinois to Missouri (average of $77). Flying from Illinois to Missouri in February is currently the most expensive (average of $170). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from IL to MO?
Find hourly flight availability from Illinois to Missouri. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated February 3, 2026.
One of the essential ways to save on airfare from Illinois to Missouri is to remain as flexible as possible. Flights that are at noon tend to be the most expensive. A flight in the morning could potentially save you up to 9% on airfare.
What is the cheapest day to fly from Illinois to Missouri?
Use this chart to determine the cheapest time to fly round-trip from Illinois to Missouri. Price data was last updated on January 31, 2026.
Travelers seeking maximum savings on their Illinois to Missouri flight should consider departing on Friday afternoons when fares are most often at their lowest. Saturday afternoons flights should be avoided if possible as fares are typically the most expensive at this time.
Weekly flight availability from Illinois to Missouri
Explore weekly flight availability from Illinois to Missouri. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated February 3, 2026.
The most flights from USIL to USMO are scheduled on a Tuesday (54 on average). You will have fewer flight options on Saturday, which is when the least amount of flights are scheduled (30 on average).
Reviews of airlines servicing Missouri
Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated February 3, 2026.
Read reviews from past customers who have flown Southwest, Contour, and United Airlines from Illinois to Missouri. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Boarding
8.1
Crew
8.6
Overall
8.0
Comfort
8.0
Food
7.0
Entertainment
7.5
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Boarding
8.1
Crew
8.6
Overall
8.0
Comfort
8.0
Food
7.0
Entertainment
7.5
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Boarding
8.1
Crew
8.6
Overall
8.0
Comfort
8.0
Food
7.0
Entertainment
7.5
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Boarding
8.1
Crew
8.6
Overall
8.0
Comfort
8.0
Food
7.0
Entertainment
7.5
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Boarding
8.1
Crew
8.6
Overall
8.0
Comfort
8.0
Food
7.0
Entertainment
7.5
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Boarding
8.1
Crew
8.6
Overall
8.0
Comfort
8.0
Food
7.0
Entertainment
7.5
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Related info for your journey
Find useful and relevant information for your journey from Illinois to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes for Illinois to Missouri
See prices for flight routes from nearby airports that may be better suited for you.
Top 5 airlines flying from Illinois to Missouri
Discover the top 5 airlines that operate flights from Illinois to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 3, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$77 | Average$346 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$105 | Average$173 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$121 | Average$387 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$144 | Average$342 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$156 | Average$215 | FlexibilityNo cancel fee | On-timeN/A |