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$64+ Cheap flights from Fort Myers (RSW) to Missouri

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/2. Fares are subject to change and may not be available on all flights or dates of travel.
RSW — STL
Oct 15 — Oct 221
Wed 10/15
Wed 10/22
1 adult, Economy
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Cheap flight deals from Fort Myers to Missouri

Keep the following information in mind while searching for Fort Myers to Missouri flight deals. Data was last updated September 15, 2025.

Round-trip from

$159
(American Airlines)

One-way from

$64
(Southwest)

Popular in

January

Cheapest in

August

Average price

$384
From Fort Myers SW Florida Intl to Missouri
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One-way flight from Fort Myers SW Florida Intl to Missouri
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Highest demand for flights based on searches. 7% potential increase in price ($40 potential increase over avg. RT price).
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Cheapest flight prices on average. 4% potential price decrease ($23 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Find flight deals from Fort Myers to Missouri

Cheapest flights from Fort Myers to Missouri
Explore the most affordable flight options available from Fort Myers to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 15, 2025.

This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/135:20 pmRSW - STL
1 stop7h 45mAmerican Airlines
Mon 11/172:05 pmSTL - RSW
1 stop4h 47mAmerican Airlines
Deal found 9/14$159
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/294:44 pmRSW - MCI
1 stop7h 29mAmerican Airlines
Mon 11/36:27 amMCI - RSW
1 stop4h 54mAmerican Airlines
Deal found 9/14$159
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/144:44 pmRSW - STL
2 stops8h 10mAmerican Airlines
Tue 10/218:30 amSTL - RSW
1 stop6h 24mAmerican Airlines
Deal found 9/14$164
This Southwest deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/165:55 pmRSW - STL
1 stop5h 30mSouthwest
Sun 10/199:05 amSTL - RSW
1 stop7h 55mSouthwest
Deal found 9/15$167
This United Airlines deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/219:10 amRSW - STL
1 stop6h 15mUnited Airlines
Sun 11/2311:05 amSTL - RSW
1 stop8h 11mUnited Airlines
Deal found 9/12$183
This United Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/185:08 pmRSW - STL
1 stop5h 47mUnited Airlines
Sat 1/37:00 amSTL - RSW
1 stop6h 37mUnited Airlines
Deal found 9/14$190
This Delta deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/128:05 amRSW - STL
1 stop6h 46mDelta
Sun 11/166:40 amSTL - RSW
1 stop5h 14mDelta
Deal found 9/14$197
This Southwest deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/57:05 pmRSW - STL
1 stop6h 00mSouthwest
Wed 10/86:55 amSTL - RSW
1 stop5h 05mSouthwest
Deal found 9/12$199
This United Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/105:14 pmRSW - STL
1 stop5h 46mUnited Airlines
Mon 10/1312:25 pmSTL - RSW
1 stop7h 43mUnited Airlines
Deal found 9/13$208
This Southwest deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/127:50 amRSW - STL
Nonstop2h 40mSouthwest
Sun 11/167:55 amSTL - RSW
Nonstop2h 30mSouthwest
Deal found 9/13$212
This United Airlines deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/77:05 amRSW - MCI
2 stops10h 11mUnited Airlines
Sat 10/1111:33 amMCI - RSW
1 stop5h 35mUnited Airlines
Deal found 9/12$212
This Southwest deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/296:30 amRSW - MCI
1 stop5h 15mSouthwest
Mon 11/31:30 pmMCI - RSW
1 stop5h 40mSouthwest
Deal found 9/12$216

Cheapflights Fare Finder

 
Customize your flight search to find flights from Fort Myers to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 15, 2025.
Use the filters below to find and compare flights from Fort Myers to Missouri that are best for you.

Fly from

Fort Myers

Fly to

Missouri

Route

Depart

Return

Price

Fort MyersSt. Louis

RSW - STL

RSWSTL

Fort Myers SW Florida Intl

Tue 10/14

6:39 pm-11:05 pm

1 stop5h 26m

Lambert-St Louis

Tue 10/21

8:30 am-3:54 pm

1 stop6h 24m

$159

Fort MyersKansas City

RSW - MCI

RSWMCI

Fort Myers SW Florida Intl

Wed 11/12

8:40 am-4:01 pm

1 stop8h 21m

Kansas City

Wed 11/19

6:05 am-2:57 pm

1 stop7h 52m

$159

Fort MyersSt. Louis

RSW - STL

RSWSTL

Fort Myers SW Florida Intl

Thu 10/16

5:55 pm-10:25 pm

1 stop5h 30m

Lambert-St Louis

Sun 10/19

9:05 am-6:00 pm

1 stop7h 55m

$167

Fort MyersSt. Louis

RSW - STL

RSWSTL

Fort Myers SW Florida Intl

Wed 11/12

8:05 am-1:51 pm

1 stop6h 46m

Lambert-St Louis

Sun 11/16

6:40 am-12:54 pm

1 stop5h 14m

$197

Fort MyersSt. Louis

RSW - STL

RSWSTL

Fort Myers SW Florida Intl

Sun 10/5

7:05 pm-12:05 am

1 stop6h 00m

Lambert-St Louis

Wed 10/8

6:55 am-1:00 pm

1 stop5h 05m

$199

Fort MyersKansas City

RSW - MCI

RSWMCI

Fort Myers SW Florida Intl

Tue 10/7

7:05 am-4:16 pm

2 stops10h 11m

Kansas City

Sat 10/11

11:33 am-6:08 pm

1 stop5h 35m

$212

Fort MyersKansas City

RSW - MCI

RSWMCI

Fort Myers SW Florida Intl

Wed 10/29

6:30 am-10:45 am

1 stop5h 15m

Kansas City

Mon 11/3

1:30 pm-8:10 pm

1 stop5h 40m

$216

Fort MyersSt. Louis

RSW - STL

RSWSTL

Fort Myers SW Florida Intl

Tue 9/30

7:00 am-9:59 am

1 stop3h 59m

Lambert-St Louis

Sat 10/18

7:05 am-3:06 pm

1 stop7h 01m

$217

Fort MyersKansas City

RSW - MCI

RSWMCI

Fort Myers SW Florida Intl

Fri 10/3

6:15 pm-10:23 pm

1 stop5h 08m

Kansas City

Fri 10/10

6:47 pm-12:39 am

1 stop4h 52m

$217

Fort MyersKansas City

RSW - MCI

RSWMCI

Fort Myers SW Florida Intl

Thu 12/11

7:50 pm-11:56 pm

1 stop5h 06m

Kansas City

Sun 12/14

6:38 pm-12:37 am

1 stop4h 59m

$217

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/14

Showing 1-10 of 54 results
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Best time to book a flight from Fort Myers to Missouri

Have a flexible travel schedule? Discover the best time to fly to Missouri from Fort Myers with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Fort Myers to Missouri

What is the cheapest month to book a flight from Fort Myers to Missouri?

Currently, August is the cheapest month in which you can book a flight from Fort Myers to Missouri (average of $311). Flying from Fort Myers to Missouri in March is currently the most expensive (average of $356). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from RSW to MO?

Find hourly flight availability from Fort Myers to Missouri. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 15, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Fort Myers to Missouri as you normally would.

Reviews of airlines servicing Missouri

Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated September 15, 2025.
Peruse reviews from past customers who have flown with Southwest, Delta, and American Airlines from Fort Myers to Missouri to help guide your decision. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,245 reviews

Boarding

8.1

Food

7.0

Overall

8.0

Crew

8.6

Entertainment

7.5

Comfort

8.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Southwest
8.0
Very good
4,245 reviews
Southwest
8.0
Very good
4,245 reviews

Boarding

8.1

Food

7.0

Overall

8.0

Crew

8.6

Entertainment

7.5

Comfort

8.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Delta
8.0
Very good
7,956 reviews
Southwest
8.0
Very good
4,245 reviews

Boarding

8.1

Food

7.0

Overall

8.0

Crew

8.6

Entertainment

7.5

Comfort

8.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
American Airlines
7.2
Good
10,000 reviews
Southwest
8.0
Very good
4,245 reviews

Boarding

8.1

Food

7.0

Overall

8.0

Crew

8.6

Entertainment

7.5

Comfort

8.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines

Related info for your journey

Find useful and relevant information for your journey from Fort Myers to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Fort Myers to Missouri?

    Fort Myers SW Florida Intl (RSW) is the airport you will fly out of if you book a flight from Fort Myers to Missouri. It is only a 10.0 mi journey to SW Florida Intl (RSW) from Fort Myers’s city center.

  • How popular is this Fort Myers to Missouri flight route?

    The Fort Myers SW Florida Intl to Missouri flight path was viewed by 18 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

  • How long is the flight from Fort Myers to Missouri?

    Departing from Fort Myers to Missouri will take you 5h 26m. There are 980 mi between Fort Myers and Missouri. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the most popular routes from Fort Myers to Missouri?

    While some choose either Fort Myers SW Florida Intl - Lambert-St Louis or Fort Myers SW Florida Intl - Springfield-Branson, Fort Myers SW Florida Intl - Kansas City is the most popular route from Fort Myers to Missouri.

  • What are the cheapest flights from Fort Myers to Missouri?

    On average you can expect to pay $280 for a flight from Fort Myers to Missouri. The cheapest flight overall is $68 while the most popular route, (Fort Myers SW Florida Intl - Kansas City) is currently priced at $217.

  • Can I find deals for flights from Fort Myers to Missouri that include hotel bookings?

    Yes. In addition to deals on Fort Myers to Missouri flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Fort Myers to Missouri?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Fort Myers to Missouri.

  • Can I find deals for business class flights from Fort Myers to Missouri?

    Yes. Cheapflights offers flight deals from Fort Myers to Missouri by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Fort Myers to Missouri?

    Currently, August is the cheapest month in which you can book a flight from Fort Myers to Missouri (average of $311). Flying from Fort Myers to Missouri in March is currently the most expensive (average of $356). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Fort Myers to Missouri

See prices for flight routes from nearby airports that may be better suited for you.
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Top 3 airlines flying from Fort Myers to Missouri

Discover the top 3 airlines that operate flights from Fort Myers to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 15, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$158Average$444FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$177Average$410FlexibilityNo cancel feeOn-time63%
DeltaCheapest$196Average$409FlexibilityNo cancel feeOn-timeN/A

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