$64+ Cheap flights from Detroit Metropolitan Wayne County Airport (DTW) to Missouri
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/4. Fares are subject to change and may not be available on all flights or dates of travel.
DTW — STL
mrt. 13 — mrt. 201
1 adult, Economy
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Cheapest flights from Detroit to MissouriExplore the most affordable flight options available from Detroit to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on februari 11, 2026.
Explore the most affordable flight options available from Detroit to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on februari 11, 2026.
This Kiwi.com deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
do 3/55:33 pm
DTW
- STL
1 stop19h 16m
Frontier
ma 3/92:09 pm
STL
- DTW
1 stop16h 58m
Frontier
Deal found 2/10![Frontier logo]()
$142
This Kiwi.com deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vr 2/2710:00 pm
DTW
- STL
1 stop9h 51m
Multiple Airlines
di 3/3111:27 am
STL
- DTW
1 stop10h 10m
Multiple Airlines
Deal found 2/9![Multiple Airlines logo]()
$154
This Kiwi.com deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vr 4/1710:27 pm
DTW
- MCI
1 stop16h 39m
Frontier
ma 4/202:15 pm
MCI
- DTW
1 stop6h 26m
Frontier
Deal found 2/10![Frontier logo]()
$163
This Kiwi.com deal was found by Cheapflights users on 2/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
di 2/242:35 pm
DTW
- STL
1 stop17h 16m
Multiple Airlines
za 2/288:17 pm
STL
- DTW
1 stop10h 50m
Multiple Airlines
Deal found 2/8![Multiple Airlines logo]()
$164
This Kiwi.com deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ma 3/910:10 am
DTW
- MCI
1 stop7h 13m
Multiple Airlines
ma 3/166:20 pm
MCI
- DTW
1 stop12h 47m
Multiple Airlines
Deal found 2/9![Multiple Airlines logo]()
$164
This Kiwi.com deal was found by Cheapflights users on 2/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vr 3/206:05 am
DTW
- STL
1 stop8h 29m
Multiple Airlines
ma 3/2312:16 pm
STL
- DTW
1 stop18h 51m
Multiple Airlines
Deal found 2/8![Multiple Airlines logo]()
$165
This Kiwi.com deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
do 3/125:07 pm
DTW
- STL
1 stop21h 27m
Frontier
ma 3/168:12 pm
STL
- DTW
1 stop13h 47m
Frontier
Deal found 2/9![Frontier logo]()
$166
This Kiwi.com deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
do 3/55:33 pm
DTW
- MCI
1 stop23h 50m
Frontier
ma 3/95:08 pm
MCI
- DTW
1 stop13h 59m
Frontier
Deal found 2/9![Frontier logo]()
$166
This Kiwi.com deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
wo 3/48:30 am
DTW
- MCI
1 stop8h 14m
Frontier
ma 3/95:08 pm
MCI
- DTW
1 stop13h 59m
Frontier
Deal found 2/10![Frontier logo]()
$169
This Kiwi.com deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
zo 3/15:06 pm
DTW
- STL
1 stop14h 45m
Frontier
vr 3/61:09 pm
STL
- DTW
1 stop18h 38m
Frontier
Deal found 2/11![Frontier logo]()
$171
This CheapOair deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
wo 2/258:30 am
DTW
- MCI
1 stop8h 14m
Frontier
za 2/2810:00 am
MCI
- DTW
1 stop21h 52m
Frontier
Deal found 2/10![Frontier logo]()
$171
This Kiwi.com deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
do 3/510:59 pm
DTW
- STL
2 stops13h 50m
Multiple Airlines
ma 3/92:09 pm
STL
- DTW
1 stop16h 58m
Multiple Airlines
Deal found 2/10![Multiple Airlines logo]()
$172
Best flights from Detroit to MissouriDiscover carefully curated flight deals from Detroit to Missouri that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated februari 11, 2026.
Discover carefully curated flight deals from Detroit to Missouri that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated februari 11, 2026.
This Kiwi.com deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
do 3/125:07 pm
DTW
- STL
1 stop21h 27m
Frontier
di 3/178:06 pm
STL
- DTW
2 stops19h 06m
Frontier
Deal found 2/10![Frontier logo]()
$198
This Southwest deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
wo 3/117:00 am
DTW
- STL
Nonstop1h 45m
Southwest
do 3/127:40 pm
STL
- DTW
Nonstop1h 30m
Southwest
Deal found 2/9![Southwest logo]()
$215
This Kiwi.com deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
do 2/192:35 pm
DTW
- MCI
1 stop20h 28m
Multiple Airlines
zo 2/2210:14 am
MCI
- DTW
1 stop26h 16m
Multiple Airlines
Deal found 2/10![Multiple Airlines logo]()
$227
This United Airlines deal was found by Cheapflights users on 2/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vr 6/57:30 pm
DTW
- COU
1 stop6h 00m
United Airlines
za 6/63:16 pm
COU
- DTW
1 stop4h 06m
United Airlines
Deal found 2/8![United Airlines logo]()
$258
This American Airlines deal was found by Cheapflights users on 2/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
za 4/183:30 pm
DTW
- SGF
1 stop7h 24m
American Airlines
di 4/216:05 pm
SGF
- DTW
1 stop5h 40m
American Airlines
Deal found 2/8![American Airlines logo]()
$269
This Mytrip deal was found by Cheapflights users on 2/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
di 3/316:05 am
DTW
- MCI
2 stops18h 48m
Spirit Airlines
di 4/712:24 pm
MCI
- DTW
2 stops21h 48m
Spirit Airlines
Deal found 2/7![Spirit Airlines logo]()
$289
This Frontier deal was found by Cheapflights users on 2/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ma 2/236:08 pm
DTW
- STL
1 stop6h 51m
Frontier
vr 2/278:22 pm
STL
- DTW
1 stop11h 10m
Frontier
Deal found 2/8![Frontier logo]()
$202
This CheapOair deal was found by Cheapflights users on 2/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
wo 4/221:02 pm
DTW
- MCI
1 stop11h 31m
Multiple Airlines
vr 4/242:15 pm
MCI
- DTW
1 stop6h 26m
Multiple Airlines
Deal found 2/8![Multiple Airlines logo]()
$230
This Kiwi.com deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
zo 3/85:17 pm
DTW
- STL
1 stop21h 02m
Frontier
zo 3/158:06 pm
STL
- DTW
2 stops51h 23m
Frontier
Deal found 2/10![Frontier logo]()
$217
This Southwest deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
za 3/78:15 pm
DTW
- STL
1 stop3h 40m
Southwest
ma 3/94:55 pm
STL
- DTW
2 stops6h 20m
Southwest
Deal found 2/10![Southwest logo]()
$240
This American Airlines deal was found by Cheapflights users on 2/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
za 4/256:00 am
DTW
- SGF
1 stop4h 51m
American Airlines
za 5/26:24 pm
SGF
- DTW
1 stop5h 01m
American Airlines
Deal found 2/8![American Airlines logo]()
$269
This Southwest deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
do 3/56:00 am
DTW
- STL
2 stops7h 30m
Southwest
ma 3/92:15 pm
STL
- DTW
2 stops7h 50m
Southwest
Deal found 2/10![Southwest logo]()
$245
This Kiwi.com deal was found by Cheapflights users on 2/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
di 3/178:08 pm
DTW
- MCI
2 stops15h 50m
Multiple Airlines
vr 3/206:23 pm
MCI
- DTW
1 stop13h 14m
Multiple Airlines
Deal found 2/8![Multiple Airlines logo]()
$247
This United Airlines deal was found by Cheapflights users on 2/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
za 2/2110:28 am
DTW
- SGF
1 stop5h 12m
United Airlines
di 2/241:25 pm
SGF
- DTW
1 stop8h 06m
United Airlines
Deal found 2/7![United Airlines logo]()
$279
This Kiwi.com deal was found by Cheapflights users on 2/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vr 2/2710:00 pm
DTW
- STL
1 stop9h 51m
Frontier
zo 3/13:49 pm
STL
- DTW
2 stops25h 39m
Frontier
Deal found 2/8![Frontier logo]()
$235
This Mytrip deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
do 3/52:35 pm
DTW
- MCI
2 stops20h 55m
Spirit Airlines
ma 3/94:24 pm
MCI
- DTW
2 stops20h 06m
Spirit Airlines
Deal found 2/9![Spirit Airlines logo]()
$301
This Southwest deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
za 3/147:00 am
DTW
- STL
Nonstop1h 45m
Southwest
ma 3/237:40 pm
STL
- DTW
Nonstop1h 30m
Southwest
Deal found 2/10![Southwest logo]()
$265
This United Airlines deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ma 3/91:52 pm
DTW
- SGF
1 stop4h 41m
United Airlines
ma 3/166:08 pm
SGF
- DTW
1 stop4h 26m
United Airlines
Deal found 2/9![United Airlines logo]()
$297
This American Airlines deal was found by Cheapflights users on 2/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
wo 4/156:00 am
DTW
- SGF
1 stop6h 14m
American Airlines
zo 4/193:36 pm
SGF
- DTW
1 stop7h 49m
American Airlines
Deal found 2/8![American Airlines logo]()
$304
This Kiwi.com deal was found by Cheapflights users on 2/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
do 4/301:46 pm
DTW
- MCI
1 stop11h 13m
Multiple Airlines
zo 5/311:13 am
MCI
- DTW
1 stop20h 57m
Multiple Airlines
Deal found 2/8![Multiple Airlines logo]()
$293
This Southwest deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
do 4/98:15 pm
DTW
- STL
Nonstop1h 40m
Southwest
zo 4/128:35 pm
STL
- DTW
Nonstop1h 30m
Southwest
Deal found 2/9![Southwest logo]()
$267
This Kiwi.com deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vr 3/69:02 am
DTW
- MCI
1 stop8h 21m
Frontier
za 3/73:40 pm
MCI
- DTW
2 stops14h 27m
Frontier
Deal found 2/10![Frontier logo]()
$281
This United Airlines deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
di 2/2410:28 am
DTW
- COU
1 stop5h 00m
United Airlines
za 2/283:10 pm
COU
- DTW
1 stop5h 59m
United Airlines
Deal found 2/9![United Airlines logo]()
$338
This Kiwi.com deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ma 3/910:59 pm
DTW
- MCI
2 stops17h 30m
Multiple Airlines
zo 3/158:40 pm
MCI
- DTW
1 stop13h 19m
Multiple Airlines
Deal found 2/10![Multiple Airlines logo]()
$310
This Kiwi.com deal was found by Cheapflights users on 2/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vr 3/2710:27 pm
DTW
- MCI
1 stop22h 28m
Frontier
ma 3/308:38 pm
MCI
- DTW
2 stops10h 29m
Frontier
Deal found 2/8![Frontier logo]()
$288
This United Airlines deal was found by Cheapflights users on 2/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
za 2/214:43 pm
DTW
- JLN
1 stop7h 45m
United Airlines
wo 2/258:54 am
JLN
- DTW
1 stop7h 31m
United Airlines
Deal found 2/7![United Airlines logo]()
$344
This Kiwi.com deal was found by Cheapflights users on 2/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vr 3/139:02 am
DTW
- MCI
1 stop9h 36m
Frontier
za 3/148:40 pm
MCI
- DTW
1 stop13h 19m
Frontier
Deal found 2/7![Frontier logo]()
$303
This American Airlines deal was found by Cheapflights users on 2/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
wo 3/2510:11 am
DTW
- COU
2 stops8h 49m
American Airlines
wo 4/110:01 am
COU
- DTW
1 stop13h 30m
American Airlines
Deal found 2/8![American Airlines logo]()
$423
This United Airlines deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
do 2/266:00 am
DTW
- COU
1 stop5h 33m
United Airlines
ma 3/23:10 pm
COU
- DTW
1 stop4h 03m
United Airlines
Deal found 2/11![United Airlines logo]()
$368
This Kiwi.com deal was found by Cheapflights users on 2/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vr 3/139:02 am
DTW
- MCI
1 stop9h 36m
Frontier
zo 3/158:40 pm
MCI
- DTW
1 stop13h 19m
Frontier
Deal found 2/7![Frontier logo]()
$309
Last-minute flights from Detroit to MissouriDiscover last-minute flight deals from Detroit to Missouri. Data last updated februari 11, 2026 and is based on user searches.
Discover last-minute flight deals from Detroit to Missouri. Data last updated februari 11, 2026 and is based on user searches.
This Frontier deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
za 2/213:17 pm
DTW
- STL
1 stop9h 42m
Frontier
wo 2/258:17 pm
STL
- DTW
1 stop10h 50m
Frontier
Deal found 2/10![Frontier logo]()
$181
This Kiwi.com deal was found by Cheapflights users on 2/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
di 2/242:35 pm
DTW
- STL
1 stop17h 16m
Multiple Airlines
za 2/288:17 pm
STL
- DTW
1 stop10h 50m
Multiple Airlines
Deal found 2/8![Multiple Airlines logo]()
$164
This CheapOair deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
wo 2/258:30 am
DTW
- MCI
1 stop8h 14m
Frontier
za 2/2810:00 am
MCI
- DTW
1 stop21h 52m
Frontier
Deal found 2/10![Frontier logo]()
$171
This Kiwi.com deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vr 2/2710:00 pm
DTW
- STL
1 stop9h 51m
Multiple Airlines
di 3/3111:27 am
STL
- DTW
1 stop10h 10m
Multiple Airlines
Deal found 2/9![Multiple Airlines logo]()
$154
This Kiwi.com deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
zo 3/15:06 pm
DTW
- STL
1 stop14h 45m
Frontier
vr 3/61:09 pm
STL
- DTW
1 stop18h 38m
Frontier
Deal found 2/11![Frontier logo]()
$171
This Kiwi.com deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
wo 3/48:30 am
DTW
- MCI
1 stop8h 14m
Frontier
ma 3/95:08 pm
MCI
- DTW
1 stop13h 59m
Frontier
Deal found 2/10![Frontier logo]()
$169
This Kiwi.com deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
do 3/55:33 pm
DTW
- STL
1 stop19h 16m
Frontier
ma 3/92:09 pm
STL
- DTW
1 stop16h 58m
Frontier
Deal found 2/10![Frontier logo]()
$142
This Kiwi.com deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
do 3/55:33 pm
DTW
- MCI
1 stop23h 50m
Frontier
ma 3/95:08 pm
MCI
- DTW
1 stop13h 59m
Frontier
Deal found 2/10![Frontier logo]()
$166
This Kiwi.com deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
do 3/510:59 pm
DTW
- STL
2 stops13h 50m
Multiple Airlines
ma 3/92:09 pm
STL
- DTW
1 stop16h 58m
Multiple Airlines
Deal found 2/10![Multiple Airlines logo]()
$172
This Kiwi.com deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ma 3/910:10 am
DTW
- MCI
1 stop7h 13m
Multiple Airlines
ma 3/166:20 pm
MCI
- DTW
1 stop12h 47m
Multiple Airlines
Deal found 2/9![Multiple Airlines logo]()
$164
This Kiwi.com deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
do 3/125:07 pm
DTW
- STL
1 stop21h 27m
Frontier
ma 3/168:12 pm
STL
- DTW
1 stop13h 47m
Frontier
Deal found 2/9![Frontier logo]()
$166
This Kiwi.com deal was found by Cheapflights users on 2/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vr 3/206:05 am
DTW
- STL
1 stop8h 29m
Multiple Airlines
ma 3/2312:16 pm
STL
- DTW
1 stop18h 51m
Multiple Airlines
Deal found 2/8![Multiple Airlines logo]()
$165
One-way flights from Detroit to MissouriSearch for one-way flight options from Detroit to Missouri. Find affordable one-way fares based on user searches. Data last updated februari 11, 2026.
Search for one-way flight options from Detroit to Missouri. Find affordable one-way fares based on user searches. Data last updated februari 11, 2026.
This Priceline deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
wo 3/48:30 am
DTW
- STL
1 stop8h 23m
Frontier
Deal found 2/10![Frontier logo]()
$64
This Priceline deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
wo 3/48:30 am
DTW
- MCI
1 stop8h 14m
Frontier
Deal found 2/10![Frontier logo]()
$64
This Kiwi.com deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
di 3/1011:54 am
DTW
- STL
1 stop22h 55m
Frontier
Deal found 2/9![Frontier logo]()
$66
This Kiwi.com deal was found by Cheapflights users on 2/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
zo 3/15:06 pm
DTW
- STL
1 stop14h 45m
Frontier
Deal found 2/8![Frontier logo]()
$71
This Kiwi.com deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ma 3/99:02 am
DTW
- STL
1 stop5h 17m
Frontier
Deal found 2/10![Frontier logo]()
$72
This Kiwi.com deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ma 3/169:02 am
DTW
- STL
1 stop5h 32m
Frontier
Deal found 2/10![Frontier logo]()
$73
This Kiwi.com deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
di 3/175:07 pm
DTW
- STL
1 stop18h 30m
Frontier
Deal found 2/10![Frontier logo]()
$74
This Kiwi.com deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
di 3/310:10 am
DTW
- STL
1 stop21h 41m
Multiple Airlines
Deal found 2/9![Multiple Airlines logo]()
$75
This Kiwi.com deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
di 4/285:09 pm
DTW
- STL
1 stop14h 41m
Frontier
Deal found 2/10![Frontier logo]()
$77
This Kiwi.com deal was found by Cheapflights users on 2/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
di 4/1412:26 pm
DTW
- STL
1 stop19h 24m
Frontier
Deal found 2/8![Frontier logo]()
$78
This Trip.com deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
di 3/245:07 pm
DTW
- MCI
1 stop18h 51m
Frontier
Deal found 2/9![Frontier logo]()
$79
This Priceline deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vr 4/1711:54 am
DTW
- STL
1 stop8h 18m
Frontier
Deal found 2/10![Frontier logo]()
$80
Find flight deals from Detroit to Missouri
Keep the following information in mind while searching for Detroit to Missouri flight deals. Data was last updated februari 11, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $142 (Kiwi.com) |
One-way from | $64 (Priceline) |
Popular in | February |
Cheapest in | August |
Average price | $378 |
Good round-trip deal | $317 or less |
Good one-way deal | $159 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Detroit to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated februari 11, 2026.
Use the filters below to find and compare flights from Detroit Metropolitan Wayne County Airport to Missouri that are best for you.
Fly from
Detroit
Fly to
Missouri
Route
Depart
Return
Price
DetroitSt. Louis
DTW - STL
DTWSTL
Detroit Metropolitan Wayne County
do 3/12
5:07 pm-1:34 pm
1 stop21h 27m
Lambert-St Louis
di 3/17
8:06 pm-4:12 pm
2 stops19h 06m
$198
DetroitSt. Louis
DTW - STL
DTWSTL
Detroit Metropolitan Wayne County
ma 2/23
6:08 pm-11:59 pm
1 stop6h 51m
Lambert-St Louis
vr 2/27
8:22 pm-8:32 am
1 stop11h 10m
$202
DetroitSt. Louis
DTW - STL
DTWSTL
Detroit Metropolitan Wayne County
wo 3/11
7:00 am-7:45 am
Nonstop1h 45m
Lambert-St Louis
do 3/12
7:40 pm-10:10 pm
Nonstop1h 30m
$215
DetroitSt. Louis
DTW - STL
DTWSTL
Detroit Metropolitan Wayne County
zo 3/8
5:17 pm-1:19 pm
1 stop21h 02m
Lambert-St Louis
zo 3/15
8:06 pm-12:29 am
2 stops51h 23m
$217
DetroitKansas City
DTW - MCI
DTWMCI
Detroit Metropolitan Wayne County
do 2/19
2:35 pm-10:03 am
1 stop20h 28m
Kansas City
zo 2/22
10:14 am-1:30 pm
1 stop26h 16m
$227
DetroitKansas City
DTW - MCI
DTWMCI
Detroit Metropolitan Wayne County
wo 4/22
1:02 pm-11:33 pm
1 stop11h 31m
Kansas City
vr 4/24
2:15 pm-9:41 pm
1 stop6h 26m
$230
DetroitSt. Louis
DTW - STL
DTWSTL
Detroit Metropolitan Wayne County
vr 2/27
10:00 pm-6:51 am
1 stop9h 51m
Lambert-St Louis
zo 3/1
3:49 pm-6:28 pm
2 stops25h 39m
$235
DetroitSt. Louis
DTW - STL
DTWSTL
Detroit Metropolitan Wayne County
za 3/7
8:15 pm-10:55 pm
1 stop3h 40m
Lambert-St Louis
ma 3/9
4:55 pm-12:15 am
2 stops6h 20m
$240
DetroitSt. Louis
DTW - STL
DTWSTL
Detroit Metropolitan Wayne County
do 3/5
6:00 am-12:30 pm
2 stops7h 30m
Lambert-St Louis
ma 3/9
2:15 pm-11:05 pm
2 stops7h 50m
$245
DetroitKansas City
DTW - MCI
DTWMCI
Detroit Metropolitan Wayne County
di 3/17
8:08 pm-10:58 am
2 stops15h 50m
Kansas City
vr 3/20
6:23 pm-8:37 am
1 stop13h 14m
$247
Showing 1-10 of 59 results
Best time to book a flight from Detroit to Missouri
Have a flexible travel schedule? Discover the best time to fly to Missouri from Detroit with our price prediction graph.
DTW-STL
DTW-MCI
DTW-SGF
DTW-JLN
DTW-COU
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Detroit Metropolitan Wayne County Airport to Missouri
DTW-USMO
DTW-STL
DTW-MCI
DTW-SGF
DTW-JLN
What is the cheapest month to book a flight from Detroit Metropolitan Wayne County Airport to Missouri?
Currently, August is the cheapest month in which you can book a flight from Detroit Metropolitan Wayne County Airport to Missouri (average of $40). Flying from Detroit Metropolitan Wayne County Airport to Missouri in January is currently the most expensive (average of $253). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from DTW to MO?
Find hourly flight availability from Detroit to Missouri. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated februari 11, 2026.
One of the essential ways to save on airfare from Detroit Metropolitan Wayne County Airport to Missouri is to remain as flexible as possible. Flights that are in the afternoon tend to be the most expensive. A flight at noon could potentially save you up to 5% on airfare.
What is the cheapest day to fly from Detroit Metropolitan Wayne County Airport to Missouri?
Use this chart to determine the cheapest time to fly round-trip from Detroit to Missouri. Price data was last updated on February 7, 2026.
Travelers seeking maximum savings on their Detroit Metropolitan Wayne County Airport to Missouri flight should consider departing on Sunday at noon when fares are most often at their lowest. Monday afternoons flights should be avoided if possible as fares are typically the most expensive at this time.
Weekly flight availability from Detroit Metropolitan Wayne County Airport to Missouri
Explore weekly flight availability from Detroit to Missouri. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated februari 11, 2026.
The most flights from DTW to USMO are scheduled on a Monday (13 on average). You will have fewer flight options on Thursday, which is when the least amount of flights are scheduled (5 on average).
Reviews of airlines servicing Missouri
Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated februari 11, 2026.
Peruse reviews from past customers who have flown with Southwest, Delta, and United Airlines from Detroit Metropolitan Wayne County Airport to Missouri to help guide your decision. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
7.5
Overall
8.0
Boarding
8.1
Food
7.0
Crew
8.6
Comfort
8.0
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Entertainment
7.5
Overall
8.0
Boarding
8.1
Food
7.0
Crew
8.6
Comfort
8.0
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Entertainment
7.5
Overall
8.0
Boarding
8.1
Food
7.0
Crew
8.6
Comfort
8.0
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Entertainment
7.5
Overall
8.0
Boarding
8.1
Food
7.0
Crew
8.6
Comfort
8.0
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Entertainment
7.5
Overall
8.0
Boarding
8.1
Food
7.0
Crew
8.6
Comfort
8.0
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Entertainment
7.5
Overall
8.0
Boarding
8.1
Food
7.0
Crew
8.6
Comfort
8.0
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Related info for your journey
Find useful and relevant information for your journey from Detroit to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Detroit to Missouri
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Complete your trip
Complete your trip to Missouri by adding a car rental and/or hotel reservation to your travel itinerary.
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Find flights from Detroit to Missouri, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Detroit and Missouri flights
Browse other Detroit and Missouri flight options. Last updated on februari 11, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Detroit to Missouri flights
Consider these flights traveling from Detroit to Missouri.
Top 6 airlines flying from Detroit to Missouri
Discover the top 6 airlines that operate flights from Detroit to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated februari 11, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$28 | Average$138 | FlexibilityNo cancel fee | On-time65% | |
| Cheapest$111 | Average$228 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$121 | Average$370 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$137 | Average$373 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$238 | Average$413 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$292 | Average$413 | FlexibilityNo cancel fee | On-time71% |