$69+ Cheap flights from Detroit (DTT) to Missouri
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/28. Fares are subject to change and may not be available on all flights or dates of travel.
DTT — STL
Mar 25 — Apr 11
1 adult, Economy
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Find cheap flights from Detroit to Missouri with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Cheapest flights from Detroit to MissouriExplore the most affordable flight options available from Detroit to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 23, 2026.
Explore the most affordable flight options available from Detroit to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 23, 2026.
This Kiwi.com deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/186:05 am
DTW
- STL
1 stop5h 32m
Multiple Airlines
Mon 3/2312:16 pm
STL
- DTW
1 stop18h 51m
Multiple Airlines
Deal found 2/20![Multiple Airlines logo]()
$147
This Kiwi.com deal was found by Cheapflights users on 2/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/169:02 am
DTW
- STL
1 stop5h 32m
Frontier
Mon 3/2312:16 pm
STL
- DTW
1 stop18h 51m
Frontier
Deal found 2/21![Frontier logo]()
$151
This Kiwi.com deal was found by Cheapflights users on 2/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/85:17 pm
DTW
- STL
1 stop21h 02m
Frontier
Wed 3/1111:32 am
STL
- DTW
1 stop19h 35m
Frontier
Deal found 2/21![Frontier logo]()
$154
This Kiwi.com deal was found by Cheapflights users on 2/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/18:49 pm
DTW
- STL
1 stop11h 01m
Frontier
Wed 5/68:13 pm
STL
- DTW
1 stop19h 01m
Frontier
Deal found 2/22![Frontier logo]()
$155
This Kiwi.com deal was found by Cheapflights users on 2/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/217:04 pm
DTW
- STL
1 stop12h 46m
Frontier
Thu 4/2311:25 am
STL
- DTW
1 stop20h 45m
Frontier
Deal found 2/22![Frontier logo]()
$156
This Kiwi.com deal was found by Cheapflights users on 2/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/235:07 pm
DTW
- STL
1 stop18h 25m
Frontier
Wed 3/258:12 pm
STL
- DTW
1 stop13h 47m
Frontier
Deal found 2/21![Frontier logo]()
$159
This Kiwi.com deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/246:05 am
DTW
- STL
1 stop5h 27m
Multiple Airlines
Wed 3/258:12 pm
STL
- DTW
1 stop13h 47m
Multiple Airlines
Deal found 2/20![Multiple Airlines logo]()
$160
This Frontier deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/1311:54 am
DTW
- MCI
1 stop9h 04m
Frontier
Thu 4/1611:53 am
MCI
- DTW
1 stop5h 53m
Frontier
Deal found 2/20![Frontier logo]()
$160
This Kiwi.com deal was found by Cheapflights users on 2/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/306:30 am
DTW
- STL
1 stop5h 00m
Multiple Airlines
Wed 5/68:13 pm
STL
- DTW
1 stop19h 01m
Multiple Airlines
Deal found 2/22![Multiple Airlines logo]()
$164
This Kiwi.com deal was found by Cheapflights users on 2/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/2210:27 pm
DTW
- STL
1 stop12h 22m
Frontier
Tue 3/2411:27 am
STL
- DTW
1 stop19h 40m
Frontier
Deal found 2/22![Frontier logo]()
$166
This Kiwi.com deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/511:54 am
DTW
- STL
1 stop22h 54m
Frontier
Tue 4/711:21 am
STL
- DTW
1 stop19h 41m
Frontier
Deal found 2/19![Frontier logo]()
$168
This Kiwi.com deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/2210:27 pm
DTW
- STL
1 stop12h 22m
Frontier
Thu 3/2611:21 am
STL
- DTW
1 stop19h 46m
Frontier
Deal found 2/20![Frontier logo]()
$173
Best flights from Detroit to MissouriDiscover carefully curated flight deals from Detroit to Missouri that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated February 23, 2026.
Discover carefully curated flight deals from Detroit to Missouri that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated February 23, 2026.
This Southwest deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/157:00 am
DTW
- STL
Nonstop1h 45m
Southwest
Sat 4/189:55 am
STL
- DTW
1 stop5h 15m
Southwest
Deal found 2/19![Southwest logo]()
$216
This United Airlines deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/74:18 pm
DTW
- STL
1 stop6h 29m
United Airlines
Sat 4/119:16 am
STL
- DTW
2 stops8h 35m
United Airlines
Deal found 2/19![United Airlines logo]()
$231
This American Airlines deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/155:00 am
DTW
- SGF
1 stop5h 51m
American Airlines
Sun 4/196:24 pm
SGF
- DTW
1 stop5h 01m
American Airlines
Deal found 2/19![American Airlines logo]()
$269
This Alaska Airlines deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/297:09 am
DTW
- MCI
1 stop17h 50m
Alaska Airlines
Wed 5/62:58 pm
MCI
- DTW
1 stop13h 46m
Alaska Airlines
Deal found 2/19![Alaska Airlines logo]()
$323
This Delta deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/268:42 am
DTW
- MCI
Nonstop2h 07m
Delta
Sun 5/35:46 pm
MCI
- DTW
Nonstop1h 58m
Delta
Deal found 2/19![Delta logo]()
$399
This United Airlines deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/297:18 am
DTW
- JLN
1 stop6h 54m
United Airlines
Sat 5/29:06 am
JLN
- DTW
1 stop5h 18m
United Airlines
Deal found 2/20![United Airlines logo]()
$264
This Southwest deal was found by Cheapflights users on 2/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/247:00 am
DTW
- STL
Nonstop1h 45m
Southwest
Tue 4/286:45 pm
STL
- DTW
Nonstop1h 30m
Southwest
Deal found 2/22![Southwest logo]()
$267
This American Airlines deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/185:00 am
DTW
- SGF
1 stop5h 51m
American Airlines
Tue 4/215:27 pm
SGF
- DTW
1 stop5h 05m
American Airlines
Deal found 2/19![American Airlines logo]()
$269
This Southwest deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/187:00 am
DTW
- STL
Nonstop1h 45m
Southwest
Fri 3/207:40 pm
STL
- DTW
Nonstop1h 30m
Southwest
Deal found 2/19![Southwest logo]()
$278
This Southwest deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/127:00 am
DTW
- STL
Nonstop1h 45m
Southwest
Fri 3/137:40 pm
STL
- DTW
Nonstop1h 30m
Southwest
Deal found 2/19![Southwest logo]()
$278
This Alaska Airlines deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/174:55 pm
DTW
- MCI
1 stop21h 34m
Alaska Airlines
Tue 4/212:23 pm
MCI
- DTW
1 stop14h 21m
Alaska Airlines
Deal found 2/19![Alaska Airlines logo]()
$343
This United Airlines deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/65:48 am
DTW
- COU
1 stop5h 45m
United Airlines
Tue 3/102:41 pm
COU
- DTW
1 stop6h 29m
United Airlines
Deal found 2/19![United Airlines logo]()
$313
This Southwest deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/28:10 pm
DTW
- STL
Nonstop1h 45m
Southwest
Mon 4/64:25 pm
STL
- DTW
2 stops6h 50m
Southwest
Deal found 2/19![Southwest logo]()
$280
This Alaska Airlines deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/134:55 pm
DTW
- MCI
1 stop21h 34m
Alaska Airlines
Tue 4/212:23 pm
MCI
- DTW
1 stop14h 21m
Alaska Airlines
Deal found 2/19![Alaska Airlines logo]()
$343
This United Airlines deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/179:30 pm
DTW
- COU
1 stop4h 03m
United Airlines
Mon 4/208:00 am
COU
- DTW
2 stops9h 51m
United Airlines
Deal found 2/20![United Airlines logo]()
$314
This Delta deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/207:45 pm
DTW
- MCI
Nonstop2h 00m
Delta
Mon 4/2710:36 am
MCI
- DTW
Nonstop1h 54m
Delta
Deal found 2/19![Delta logo]()
$399
This Southwest deal was found by Cheapflights users on 2/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/242:15 pm
DTW
- STL
2 stops6h 45m
Southwest
Thu 3/264:55 pm
STL
- DTW
2 stops6h 20m
Southwest
Deal found 2/21![Southwest logo]()
$286
This United Airlines deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/226:00 pm
DTW
- COU
1 stop4h 15m
United Airlines
Tue 8/253:16 pm
COU
- DTW
1 stop4h 04m
United Airlines
Deal found 2/19![United Airlines logo]()
$328
This Delta deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/227:45 pm
DTW
- MCI
Nonstop2h 00m
Delta
Wed 4/2910:36 am
MCI
- DTW
Nonstop1h 54m
Delta
Deal found 2/19![Delta logo]()
$399
This Southwest deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/76:35 am
DTW
- STL
2 stops7h 25m
Southwest
Sat 4/1110:55 am
STL
- DTW
2 stops5h 40m
Southwest
Deal found 2/19![Southwest logo]()
$286
This Alaska Airlines deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/27:09 am
DTW
- MCI
1 stop17h 50m
Alaska Airlines
Wed 5/62:58 pm
MCI
- DTW
1 stop13h 46m
Alaska Airlines
Deal found 2/19![Alaska Airlines logo]()
$383
This Delta deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/212:20 pm
DTW
- MCI
Nonstop2h 04m
Delta
Wed 5/610:36 am
MCI
- DTW
Nonstop1h 54m
Delta
Deal found 2/19![Delta logo]()
$399
This United Airlines deal was found by Cheapflights users on 2/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/237:18 am
DTW
- JLN
1 stop6h 54m
United Airlines
Thu 4/309:06 am
JLN
- DTW
1 stop5h 18m
United Airlines
Deal found 2/21![United Airlines logo]()
$334
This Alaska Airlines deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/297:09 am
DTW
- MCI
1 stop17h 50m
Alaska Airlines
Mon 5/42:58 pm
MCI
- DTW
1 stop13h 46m
Alaska Airlines
Deal found 2/19![Alaska Airlines logo]()
$393
This Southwest deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/217:00 am
DTW
- STL
Nonstop1h 45m
Southwest
Sat 3/287:40 pm
STL
- DTW
Nonstop1h 30m
Southwest
Deal found 2/19![Southwest logo]()
$298
This Delta deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/73:50 pm
DTW
- MCI
Nonstop2h 05m
Delta
Tue 4/1410:36 am
MCI
- DTW
Nonstop1h 54m
Delta
Deal found 2/19![Delta logo]()
$399
This United Airlines deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/287:18 am
DTW
- JLN
1 stop6h 54m
United Airlines
Sat 5/29:06 am
JLN
- DTW
1 stop7h 23m
United Airlines
Deal found 2/20![United Airlines logo]()
$334
This Delta deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/217:45 pm
DTW
- MCI
Nonstop2h 00m
Delta
Mon 4/2710:36 am
MCI
- DTW
Nonstop1h 54m
Delta
Deal found 2/19![Delta logo]()
$399
This United Airlines deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/182:05 pm
DTW
- SGF
1 stop4h 19m
United Airlines
Tue 4/216:00 am
SGF
- DTW
2 stops11h 23m
United Airlines
Deal found 2/19![United Airlines logo]()
$344
This Delta deal was found by Cheapflights users on 2/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/2510:35 am
DTW
- SGF
1 stop5h 39m
Delta
Wed 4/293:59 pm
SGF
- DTW
1 stop7h 45m
Delta
Deal found 2/21![Delta logo]()
$419
Last-minute flights from Detroit to MissouriDiscover last-minute flight deals from Detroit to Missouri. Data last updated February 23, 2026 and is based on user searches.
Discover last-minute flight deals from Detroit to Missouri. Data last updated February 23, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 2/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/85:17 pm
DTW
- STL
1 stop21h 02m
Frontier
Wed 3/1111:32 am
STL
- DTW
1 stop19h 35m
Frontier
Deal found 2/21![Frontier logo]()
$154
This Kiwi.com deal was found by Cheapflights users on 2/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/85:17 pm
DTW
- STL
1 stop21h 02m
Multiple Airlines
Wed 3/1111:32 am
STL
- DTW
2 stops11h 27m
Multiple Airlines
Deal found 2/22![Multiple Airlines logo]()
$179
This Kiwi.com deal was found by Cheapflights users on 2/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/169:02 am
DTW
- STL
1 stop5h 32m
Frontier
Mon 3/2312:16 pm
STL
- DTW
1 stop18h 51m
Frontier
Deal found 2/21![Frontier logo]()
$151
This Kiwi.com deal was found by Cheapflights users on 2/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/169:02 am
DTW
- MCI
1 stop9h 23m
Frontier
Wed 3/1811:45 am
MCI
- DTW
1 stop19h 22m
Frontier
Deal found 2/22![Frontier logo]()
$182
This Kiwi.com deal was found by Cheapflights users on 2/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/169:53 pm
DTW
- STL
2 stops37h 44m
Multiple Airlines
Mon 3/2312:16 pm
STL
- DTW
1 stop18h 51m
Multiple Airlines
Deal found 2/21![Multiple Airlines logo]()
$184
This Kiwi.com deal was found by Cheapflights users on 2/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/165:07 pm
DTW
- MCI
2 stops19h 22m
Multiple Airlines
Wed 3/1811:45 am
MCI
- DTW
1 stop19h 22m
Multiple Airlines
Deal found 2/22![Multiple Airlines logo]()
$204
This Kiwi.com deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/186:05 am
DTW
- STL
1 stop5h 32m
Multiple Airlines
Mon 3/2312:16 pm
STL
- DTW
1 stop18h 51m
Multiple Airlines
Deal found 2/20![Multiple Airlines logo]()
$147
This Kiwi.com deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/186:05 am
DTW
- MCI
1 stop5h 53m
Multiple Airlines
Fri 3/206:23 pm
MCI
- DTW
1 stop13h 14m
Multiple Airlines
Deal found 2/19![Multiple Airlines logo]()
$199
This Kiwi.com deal was found by Cheapflights users on 2/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/2210:27 pm
DTW
- STL
1 stop12h 22m
Frontier
Tue 3/2411:27 am
STL
- DTW
1 stop19h 40m
Frontier
Deal found 2/22![Frontier logo]()
$166
This Kiwi.com deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/2210:27 pm
DTW
- STL
1 stop12h 22m
Frontier
Thu 3/2611:21 am
STL
- DTW
1 stop19h 46m
Frontier
Deal found 2/20![Frontier logo]()
$173
This Kiwi.com deal was found by Cheapflights users on 2/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/235:07 pm
DTW
- STL
1 stop18h 25m
Frontier
Wed 3/258:12 pm
STL
- DTW
1 stop13h 47m
Frontier
Deal found 2/21![Frontier logo]()
$159
This Kiwi.com deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/246:05 am
DTW
- STL
1 stop5h 27m
Multiple Airlines
Wed 3/258:12 pm
STL
- DTW
1 stop13h 47m
Multiple Airlines
Deal found 2/20![Multiple Airlines logo]()
$160
One-way flights from Detroit to MissouriSearch for one-way flight options from Detroit to Missouri. Find affordable one-way fares based on user searches. Data last updated February 23, 2026.
Search for one-way flight options from Detroit to Missouri. Find affordable one-way fares based on user searches. Data last updated February 23, 2026.
This Kiwi.com deal was found by Cheapflights users on 2/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/287:04 pm
DTW
- STL
1 stop12h 46m
Frontier
Deal found 2/22![Frontier logo]()
$69
This Kiwi.com deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/217:04 pm
DTW
- STL
1 stop12h 46m
Frontier
Deal found 2/19![Frontier logo]()
$70
This Kiwi.com deal was found by Cheapflights users on 2/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/69:02 am
DTW
- STL
1 stop26h 28m
Frontier
Deal found 2/22![Frontier logo]()
$71
This Kiwi.com deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/246:05 am
DTW
- STL
1 stop5h 27m
Multiple Airlines
Deal found 2/20![Multiple Airlines logo]()
$74
This Kiwi.com deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/186:05 am
DTW
- STL
1 stop5h 32m
Multiple Airlines
Deal found 2/20![Multiple Airlines logo]()
$75
This Kiwi.com deal was found by Cheapflights users on 2/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/76:05 am
DTW
- STL
1 stop5h 25m
Multiple Airlines
Deal found 2/22![Multiple Airlines logo]()
$78
This Kiwi.com deal was found by Cheapflights users on 2/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/15:55 pm
DTW
- STL
1 stop24h 39m
Frontier
Deal found 2/23![Frontier logo]()
$79
This Priceline deal was found by Cheapflights users on 2/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/911:07 am
DTW
- STL
1 stop7h 27m
Frontier
Deal found 2/22![Frontier logo]()
$80
This Priceline deal was found by Cheapflights users on 2/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/1111:54 am
DTW
- MCI
1 stop9h 04m
Frontier
Deal found 2/22![Frontier logo]()
$80
This Kiwi.com deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/2410:27 pm
DTW
- MCI
1 stop16h 39m
Frontier
Deal found 2/19![Frontier logo]()
$81
This Kiwi.com deal was found by Cheapflights users on 2/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/2410:27 pm
DTW
- STL
1 stop22h 05m
Frontier
Deal found 2/22![Frontier logo]()
$82
This Kiwi.com deal was found by Cheapflights users on 2/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/1710:27 pm
DTW
- STL
1 stop22h 05m
Frontier
Deal found 2/22![Frontier logo]()
$84
Find flight deals from Detroit to Missouri
Keep the following information in mind while searching for Detroit to Missouri flight deals. Data was last updated February 23, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $147 (Kiwi.com) |
One-way from | $69 (Kiwi.com) |
Popular in | February |
Cheapest in | August |
Average price | $439 |
Good round-trip deal | $319 or less |
Good one-way deal | $169 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Detroit to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 23, 2026.
Use the filters below to find and compare flights from Detroit to Missouri that are best for you.
Fly from
Detroit
Fly to
Missouri
Route
Depart
Return
Price
DetroitSt. Louis
DTW - STL
DTWSTL
Detroit Metropolitan Wayne County
Wed 4/15
7:00 am-7:45 am
Nonstop1h 45m
Lambert-St Louis
Sat 4/18
9:55 am-4:10 pm
1 stop5h 15m
$216
DetroitSt. Louis
DTW - STL
DTWSTL
Detroit Metropolitan Wayne County
Tue 4/7
4:18 pm-9:47 pm
1 stop6h 29m
Lambert-St Louis
Sat 4/11
9:16 am-6:51 pm
2 stops8h 35m
$231
DetroitJoplin
DTW - JLN
DTWJLN
Detroit Metropolitan Wayne County
Wed 4/29
7:18 am-1:12 pm
1 stop6h 54m
Joplin
Sat 5/2
9:06 am-3:24 pm
1 stop5h 18m
$264
DetroitSt. Louis
DTW - STL
DTWSTL
Detroit Metropolitan Wayne County
Fri 4/24
7:00 am-7:45 am
Nonstop1h 45m
Lambert-St Louis
Tue 4/28
6:45 pm-9:15 pm
Nonstop1h 30m
$267
DetroitSpringfield
DTW - SGF
DTWSGF
Detroit Metropolitan Wayne County
Wed 4/15
5:00 am-9:51 am
1 stop5h 51m
Springfield-Branson
Sun 4/19
6:24 pm-12:25 am
1 stop5h 01m
$269
DetroitSpringfield
DTW - SGF
DTWSGF
Detroit Metropolitan Wayne County
Sat 4/18
5:00 am-9:51 am
1 stop5h 51m
Springfield-Branson
Tue 4/21
5:27 pm-11:32 pm
1 stop5h 05m
$269
DetroitSt. Louis
DTW - STL
DTWSTL
Detroit Metropolitan Wayne County
Wed 3/18
7:00 am-7:45 am
Nonstop1h 45m
Lambert-St Louis
Fri 3/20
7:40 pm-10:10 pm
Nonstop1h 30m
$278
DetroitSt. Louis
DTW - STL
DTWSTL
Detroit Metropolitan Wayne County
Thu 3/12
7:00 am-7:45 am
Nonstop1h 45m
Lambert-St Louis
Fri 3/13
7:40 pm-10:10 pm
Nonstop1h 30m
$278
DetroitSt. Louis
DTW - STL
DTWSTL
Detroit Metropolitan Wayne County
Thu 4/2
8:10 pm-8:55 pm
Nonstop1h 45m
Lambert-St Louis
Mon 4/6
4:25 pm-12:15 am
2 stops6h 50m
$280
DetroitSt. Louis
DTW - STL
DTWSTL
Detroit Metropolitan Wayne County
Tue 3/24
2:15 pm-8:00 pm
2 stops6h 45m
Lambert-St Louis
Thu 3/26
4:55 pm-12:15 am
2 stops6h 20m
$286
Showing 1-10 of 60 results
Best time to book a flight from Detroit to Missouri
Have a flexible travel schedule? Discover the best time to fly to Missouri from Detroit with our price prediction graph.
DTW-STL
DTW-MCI
DTW-SGF
DTW-JLN
DTW-COU
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Detroit to Missouri
DTT-USMO
DTW-STL
DTW-MCI
DTW-SGF
DTW-JLN
What is the cheapest month to book a flight from Detroit to Missouri?
Currently, August is the cheapest month in which you can book a flight from Detroit to Missouri (average of $40). Flying from Detroit to Missouri in January is currently the most expensive (average of $253). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from DTT to MO?
Find hourly flight availability from Detroit to Missouri. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated February 23, 2026.
A simple way to save on the total cost of your ticket is to fly from Detroit to Missouri at noon. If you’re flexible enough to do this you can expect to save up to 6% on your trip compared to booking a flight in the afternoon.
What is the cheapest day to fly from Detroit to Missouri?
Use this chart to determine the cheapest time to fly round-trip from Detroit to Missouri. Price data was last updated on February 21, 2026.
Travelers seeking maximum savings on their Detroit to Missouri flight should consider departing on Sunday at noon when fares are most often at their lowest. Monday afternoons flights should be avoided if possible as fares are typically the most expensive at this time.
Weekly flight availability from Detroit to Missouri
Explore weekly flight availability from Detroit to Missouri. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated February 23, 2026.
The most flights from DTT to USMO are scheduled on a Monday (13 on average). You will have fewer flight options on Tuesday, which is when the least amount of flights are scheduled (10 on average).
How much does it cost to fly round-trip from Detroit to Missouri?
Reviews of airlines servicing Missouri
Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated February 23, 2026.
See what other customers who have flown with Southwest, Delta, and United Airlines from Detroit to Missouri have to say. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Boarding
8.1
Comfort
8.0
Overall
8.0
Food
7.0
Entertainment
7.5
Crew
8.6
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Boarding
8.1
Comfort
8.0
Overall
8.0
Food
7.0
Entertainment
7.5
Crew
8.6
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Boarding
8.1
Comfort
8.0
Overall
8.0
Food
7.0
Entertainment
7.5
Crew
8.6
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Boarding
8.1
Comfort
8.0
Overall
8.0
Food
7.0
Entertainment
7.5
Crew
8.6
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Boarding
8.1
Comfort
8.0
Overall
8.0
Food
7.0
Entertainment
7.5
Crew
8.6
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Boarding
8.1
Comfort
8.0
Overall
8.0
Food
7.0
Entertainment
7.5
Crew
8.6
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Related info for your journey
Find useful and relevant information for your journey from Detroit to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Detroit to Missouri
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Missouri by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Detroit to Missouri by cabin class
Find flights from Detroit to Missouri, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Detroit and Missouri flights
Browse other Detroit and Missouri flight options. Last updated on February 23, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Detroit to Missouri flights
Consider these flights traveling from Detroit to Missouri.
Top 6 airlines flying from Detroit to Missouri
Discover the top 6 airlines that operate flights from Detroit to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 23, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$28 | Average$138 | FlexibilityNo cancel fee | On-time65% | |
| Cheapest$111 | Average$228 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$121 | Average$396 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$121 | Average$375 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$238 | Average$413 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$292 | Average$406 | FlexibilityNo cancel fee | On-time71% |