How long is the flight from Detroit to Missouri?

United Airlines, Southwest, and Spirit Airlines can get you from Detroit to Missouri in just under 2h. Your travel time can differ by up to 28h 09m. The distance from Detroit to Missouri is about 439 mi. Both multi-stop and nonstop flights can be found to your destination and back.

What are the cheapest airlines to fly from Detroit to Missouri one-way?

To fly one-way, consider booking your trip with Spirit Airlines, which is currently one of the cheapest options available, starting at $36. Frontier flights start at $48 while deals on Delta start at $60 one-way.

In terms of precipitation, rainfall in Missouri ranges from 2.2 - 4.7 inches per month. May is typically the wettest month, when rainfall can reach 4.7 in. February is typically the driest time to visit Missouri when rainfall is around 2.2 in.

If weather is an important factor for your trip to Missouri, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 80.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 32.0 F).

What are the most popular routes from Detroit to Missouri?

The most popular route from Detroit to Missouri is Detroit Metropolitan Wayne County - Lambert-St Louis. You may also consider Detroit Metropolitan Wayne County - Kansas City or Detroit Metropolitan Wayne County - Springfield-Branson.

What are the cheapest flights from Detroit to Missouri?

While on average a flight from Detroit to Missouri is generally $349, our data shows the cheapest flight currently is $136. When looking at the most popular route, (Detroit Metropolitan Wayne County - Lambert-St Louis), you can expect to pay $160 for that flight.

What are the most reliable airlines from Detroit to Missouri?

Consider Air France (82%), Korean Air (65%) or KLM (65%) when booking your flight. These represent the most reliable airlines when flying from Detroit to Missouri.

What are the most popular airlines that fly from Detroit to Missouri?

Before booking your flight from Detroit to Missouri check out the most popular airlines for this route: Delta, Southwest or Spirit Airlines.

What airport do you fly from for flights from Detroit to Missouri?

If you book a flight to Missouri from Detroit, you will be flying from All airports, which is the city’s only airport. Detroit All airports (DTT) is located 0.6 mi from the center of Detroit.

Can I find deals for flights from Detroit to Missouri that include hotel bookings?

Yes. In addition to deals on Detroit to Missouri flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Detroit to Missouri?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Detroit to Missouri.

Can I find deals for business class flights from Detroit to Missouri?

Yes. Cheapflights offers flight deals from Detroit to Missouri by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$60+ Flights from Detroit to Missouri

Q: How much does it cost to fly round-trip from Detroit to Missouri?

Airfare is below average for this route at the moment. Detroit to Missouri flights typically cost between $290 and $525 in January. The cheapest round-trip price found within the last 3 days was $160 on Multiple Airlines (Jan 26-Jan 31).

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Cheap flight deals from Detroit to Missouri

Cheapest flights from Detroit to Missouri
Explore the most affordable flight options available from Detroit to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 31, 2025.

Wed 12/316:00 amDTW - STL

1 stop11h 00mAmerican Airlines

Sat 1/35:00 amSTL - DTW

1 stop8h 52mAmerican Airlines

Deal found 12/29

$520

Tue 12/303:32 pmDTW - STL

1 stop18h 03mAmerican Airlines

Tue 1/610:17 amSTL - DTW

1 stop12h 26mAmerican Airlines

Deal found 12/30

$556

Wed 12/317:16 amDTW - STL

1 stop9h 44mAmerican Airlines

Sun 1/45:00 amSTL - DTW

1 stop10h 29mAmerican Airlines

Deal found 12/29

$571

Wed 12/313:39 pmDTW - STL

2 stops27h 57mMultiple Airlines

Sun 1/410:57 amSTL - DTW

1 stop20h 10mMultiple Airlines

Deal found 12/28

$577

Wed 12/317:16 amDTW - MCI

1 stop12h 10mAmerican Airlines

Sat 1/31:53 pmMCI - DTW

1 stop9h 51mAmerican Airlines

Deal found 12/29

$606

Tue 12/303:32 pmDTW - STL

1 stop9h 23mAmerican Airlines

Mon 1/55:00 amSTL - DTW

1 stop10h 29mAmerican Airlines

Deal found 12/28

$642

Mon 12/2910:10 amDTW - STL

1 stop10h 20mAmerican Airlines

Tue 1/66:52 amSTL - DTW

1 stop7h 59mAmerican Airlines

Deal found 12/28

$643

Tue 12/307:55 pmDTW - MCI

Nonstop2h 10mDelta

Thu 1/15:42 pmMCI - DTW

Nonstop2h 00mDelta

Deal found 12/28

$659

Tue 12/309:20 pmDTW - STL

Nonstop1h 40mSouthwest

Tue 1/65:55 pmSTL - DTW

Nonstop1h 30mSouthwest

Deal found 12/30

$661

Tue 12/306:00 pmDTW - MCI

1 stop4h 50mUnited Airlines

Fri 1/27:40 amMCI - DTW

2 stops10h 24mUnited Airlines

Deal found 12/30

$664

Tue 12/307:55 pmDTW - MCI

Nonstop2h 10mDelta

Fri 1/25:43 amMCI - DTW

1 stop7h 53mDelta

Deal found 12/29

$669

Tue 12/309:20 pmDTW - STL

Nonstop1h 40mSouthwest

Mon 1/57:40 amSTL - DTW

1 stop8h 05mSouthwest

Deal found 12/28

$671

Best flights from Detroit to Missouri
Discover carefully curated flight deals from Detroit to Missouri that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated December 31, 2025.

Wed 1/217:00 amDTW - STL

1 stop17h 33mMultiple Airlines

Fri 1/235:42 pmSTL - DTW

1 stop19h 39mMultiple Airlines

Deal found 12/30

$221

Tue 1/276:40 pmDTW - STL

1 stop6h 19mUnited Airlines

Tue 2/36:40 pmSTL - DTW

1 stop3h 57mUnited Airlines

Deal found 12/29

$233

Mon 1/265:50 amDTW - STL

Nonstop2h 00mSouthwest

Mon 2/25:55 pmSTL - DTW

Nonstop1h 30mSouthwest

Deal found 12/29

$237

Mon 1/2611:00 amDTW - MCI

3 stops30h 09mSpirit Airlines

Mon 2/211:26 amMCI - DTW

2 stops9h 42mSpirit Airlines

Deal found 12/28

$245

Thu 1/2210:35 amDTW - SGF

1 stop6h 40mDelta

Thu 1/295:00 pmSGF - DTW

1 stop6h 44mDelta

Deal found 12/28

$269

Sat 4/186:00 amDTW - SGF

1 stop6h 04mAmerican Airlines

Tue 4/216:07 pmSGF - DTW

1 stop4h 13mAmerican Airlines

Deal found 12/29

$269

Fri 3/69:02 amDTW - MCI

1 stop8h 18mFrontier

Sun 3/88:40 pmMCI - DTW

2 stops20h 00mFrontier

Deal found 12/30

$358

Tue 2/310:07 pmDTW - MCI

2 stops37h 24mMultiple Airlines

Tue 2/105:04 pmMCI - DTW

1 stop14h 53mMultiple Airlines

Deal found 12/29

$231

Thu 1/225:50 amDTW - STL

Nonstop2h 00mSouthwest

Mon 1/265:55 pmSTL - DTW

Nonstop1h 30mSouthwest

Deal found 12/29

$237

Mon 1/265:50 amDTW - STL

Nonstop2h 00mSouthwest

Sat 1/315:45 pmSTL - DTW

Nonstop1h 30mSouthwest

Deal found 12/29

$237

Wed 1/1411:05 amDTW - COU

1 stop4h 30mUnited Airlines

Sun 1/183:10 pmCOU - DTW

1 stop6h 00mUnited Airlines

Deal found 12/29

$268

Wed 4/296:00 amDTW - SGF

1 stop5h 24mAmerican Airlines

Sat 5/22:31 pmSGF - DTW

1 stop7h 30mAmerican Airlines

Deal found 12/29

$269

Wed 1/285:00 amDTW - MCI

3 stops30h 31mSpirit Airlines

Wed 2/45:04 pmMCI - DTW

3 stops26h 59mSpirit Airlines

Deal found 12/30

$281

Sat 4/256:00 amDTW - SGF

1 stop6h 29mAmerican Airlines

Sat 5/22:31 pmSGF - DTW

1 stop7h 30mAmerican Airlines

Deal found 12/28

$269

Fri 1/236:00 amDTW - SGF

2 stops9h 38mUnited Airlines

Sun 1/253:14 pmSGF - DTW

1 stop4h 12mUnited Airlines

Deal found 12/29

$274

Sat 1/106:15 amDTW - SGF

1 stop6h 56mDelta

Mon 1/125:00 pmSGF - DTW

1 stop5h 42mDelta

Deal found 12/28

$309

Thu 1/226:00 amDTW - SGF

1 stop7h 15mAmerican Airlines

Thu 1/2912:45 pmSGF - DTW

1 stop6h 59mAmerican Airlines

Deal found 12/29

$269

Sat 2/1412:55 pmDTW - STL

1 stop7h 55mSouthwest

Sun 2/156:40 pmSTL - DTW

Nonstop1h 30mSouthwest

Deal found 12/29

$288

Thu 3/1911:54 amDTW - MCI

1 stop9h 01mMultiple Airlines

Tue 3/2411:26 amMCI - DTW

1 stop12h 13mMultiple Airlines

Deal found 12/30

$320

Fri 5/2912:22 pmDTW - MCI

1 stop12h 37mSpirit Airlines

Mon 6/16:00 amMCI - DTW

1 stop12h 13mSpirit Airlines

Deal found 12/29

$322

Sat 1/312:40 pmDTW - STL

2 stops10h 19mUnited Airlines

Mon 2/28:05 amSTL - DTW

2 stops8h 47mUnited Airlines

Deal found 12/30

$294

Sat 5/99:25 amDTW - SGF

1 stop6h 28mDelta

Thu 5/146:45 pmSGF - DTW

1 stop5h 00mDelta

Deal found 12/30

$334

Wed 1/215:50 amDTW - STL

Nonstop2h 00mSouthwest

Fri 1/236:50 amSTL - DTW

1 stop4h 55mSouthwest

Deal found 12/30

$299

Wed 4/227:20 pmDTW - MCI

1 stop16h 47mSpirit Airlines

Fri 4/2412:12 pmMCI - DTW

1 stop10h 47mSpirit Airlines

Deal found 12/30

$336

Thu 2/129:10 amDTW - COU

1 stop6h 18mUnited Airlines

Thu 2/1911:15 amCOU - DTW

1 stop5h 10mUnited Airlines

Deal found 12/29

$328

Tue 1/135:15 amDTW - MCI

1 stop11h 54mSpirit Airlines

Sat 1/177:00 amMCI - DTW

1 stop10h 25mSpirit Airlines

Deal found 12/29

$336

Fri 2/274:10 pmDTW - STL

Nonstop1h 40mSouthwest

Sun 3/18:10 pmSTL - DTW

Nonstop1h 30mSouthwest

Deal found 12/28

$319

Tue 1/204:45 pmDTW - JLN

1 stop7h 45mUnited Airlines

Sat 1/248:52 amJLN - DTW

1 stop7h 11mUnited Airlines

Deal found 12/28

$334

Fri 2/134:10 pmDTW - STL

Nonstop1h 40mSouthwest

Sun 2/159:10 amSTL - DTW

1 stop5h 20mSouthwest

Deal found 12/29

$329

Tue 2/102:19 pmDTW - JLN

1 stop4h 15mUnited Airlines

Sat 2/148:54 amJLN - DTW

1 stop7h 31mUnited Airlines

Deal found 12/30

$334

Last-minute flights from Detroit to Missouri
Discover last-minute flight deals from Detroit to Missouri. Data last updated December 31, 2025 and is based on user searches.

Tue 1/138:00 amDTW - STL

2 stops31h 48mFrontier

Sat 1/178:32 pmSTL - DTW

1 stop16h 45mFrontier

Deal found 12/29

$191

Tue 1/1311:00 amDTW - STL

1 stop20h 51mMultiple Airlines

Sat 1/178:32 pmSTL - DTW

1 stop16h 45mMultiple Airlines

Deal found 12/29

$199

Wed 1/2111:05 amDTW - STL

1 stop4h 25mUnited Airlines

Sat 1/243:11 pmSTL - DTW

1 stop5h 59mUnited Airlines

Deal found 12/30

$182

Thu 1/226:00 amDTW - STL

2 stops18h 33mMultiple Airlines

Mon 1/265:42 pmSTL - DTW

1 stop16h 12mMultiple Airlines

Deal found 12/30

$172

Fri 1/237:14 pmDTW - STL

1 stop12h 37mMultiple Airlines

Sun 1/255:42 pmSTL - DTW

2 stops22h 27mMultiple Airlines

Deal found 12/30

$192

Sun 1/2510:07 pmDTW - STL

2 stops26h 26mMultiple Airlines

Fri 1/3011:18 amSTL - DTW

1 stop7h 28mMultiple Airlines

Deal found 12/29

$195

Mon 1/2610:07 pmDTW - STL

2 stops26h 26mMultiple Airlines

Sat 1/313:46 pmSTL - DTW

1 stop23h 33mMultiple Airlines

Deal found 12/29

$160

Mon 1/263:14 pmDTW - STL

1 stop9h 19mFrontier

Sat 1/313:46 pmSTL - DTW

1 stop23h 33mFrontier

Deal found 12/29

$173

Tue 1/2711:50 amDTW - STL

1 stop12h 43mMultiple Airlines

Tue 2/35:42 pmSTL - DTW

1 stop19h 10mMultiple Airlines

Deal found 12/30

$170

Wed 1/282:06 pmDTW - MCI

2 stops21h 25mMultiple Airlines

Sun 2/18:41 pmMCI - DTW

1 stop18h 38mMultiple Airlines

Deal found 12/29

$188

Thu 1/292:36 pmDTW - MCI

2 stops20h 55mMultiple Airlines

Sun 2/18:41 pmMCI - DTW

1 stop18h 38mMultiple Airlines

Deal found 12/30

$174

Fri 1/305:05 amDTW - MCI

2 stops15h 46mMultiple Airlines

Sun 2/18:41 pmMCI - DTW

1 stop18h 38mMultiple Airlines

Deal found 12/30

$191

One-way flights from Detroit to Missouri
Search for one-way flight options from Detroit to Missouri. Find affordable one-way fares based on user searches. Data last updated December 31, 2025.

Wed 2/118:30 amDTW - MCI

1 stop8h 14mFrontier

Deal found 12/29

$60

Wed 2/258:30 amDTW - MCI

1 stop8h 14mFrontier

Deal found 12/28

$63

Wed 3/48:30 amDTW - STL

1 stop8h 23mFrontier

Deal found 12/29

$67

Wed 2/188:30 amDTW - MCI

1 stop8h 14mFrontier

Deal found 12/30

$67

Tue 2/108:30 amDTW - STL

1 stop30h 28mFrontier

Deal found 12/30

$68

Tue 2/1710:32 amDTW - MCI

1 stop30h 12mFrontier

Deal found 12/29

$68

Sat 2/145:21 pmDTW - MCI

1 stop20h 38mFrontier

Deal found 12/29

$71

Fri 1/305:14 pmDTW - STL

1 stop22h 32mFrontier

Deal found 12/30

$72

Sun 2/15:14 pmDTW - MCI

1 stop27h 37mFrontier

Deal found 12/30

$72

Sun 2/15:14 pmDTW - STL

1 stop20h 36mFrontier

Deal found 12/30

$77

Sun 2/85:14 pmDTW - MCI

1 stop27h 37mFrontier

Deal found 12/30

$77

Fri 1/237:14 pmDTW - STL

1 stop12h 37mFrontier

Deal found 12/29

$79

Find flight deals from Detroit to Missouri

Most accurate provider	eDreams 3 stars
Most trusted provider	eDreams 3 stars
Round-trip from	$148 (Kiwi.com)
One-way from	$60 (Trip.com)
Popular in	December
Cheapest in	August
Average price	$383
Good round-trip deal	$307 or less
Good one-way deal	$212 or less

Provider with most accurate pricing for Detroit (DTT)-Lambert-St Louis flight deals.

Search Deals

Provider most trusted by Cheapflights users for Detroit (DTT)-Lambert-St Louis flights.

Search Deals

From Detroit (DTT) to Missouri

Search Deals

One-way flight from Detroit (DTT) to Missouri

Search Deals

Highest demand for flights based on searches. 22% potential increase in price ($77 potential increase over avg. RT price).

Search Deals

Cheapest flight prices on average. 3% potential price decrease ($11 potential savings vs. average RT price).

Search Deals

Average for round-trip flights in December 2025

Search Deals

Price to beat on a round-trip flight from Detroit (DTT) to Missouri.

Search Deals

Price to beat on a one-way flight from Detroit (DTT) to Missouri.

Search Deals

Fly from

Fly to

Route

Depart

Return

Price

DetroitSt. Louis

DTW - STL

DTWSTL

Detroit Metropolitan Wayne County

Wed 1/21

7:00 am-11:33 pm

1 stop17h 33m

Lambert-St Louis

Fri 1/23

5:42 pm-2:21 pm

1 stop19h 39m

$221

DetroitKansas City

DTW - MCI

DTWMCI

Detroit Metropolitan Wayne County

Tue 2/3

10:07 pm-10:31 am

2 stops37h 24m

Kansas City

Tue 2/10

5:04 pm-8:57 am

1 stop14h 53m

$231

DetroitSt. Louis

DTW - STL

DTWSTL

Detroit Metropolitan Wayne County

Tue 1/27

6:40 pm-11:59 pm

1 stop6h 19m

Lambert-St Louis

Tue 2/3

6:40 pm-11:37 pm

1 stop3h 57m

$233

DetroitSt. Louis

DTW - STL

DTWSTL

Detroit Metropolitan Wayne County

Mon 1/26

5:50 am-6:50 am

Nonstop2h 00m

Lambert-St Louis

Mon 2/2

5:55 pm-8:25 pm

Nonstop1h 30m

$237

DetroitSt. Louis

DTW - STL

DTWSTL

Detroit Metropolitan Wayne County

Thu 1/22

5:50 am-6:50 am

Nonstop2h 00m

Lambert-St Louis

Mon 1/26

5:55 pm-8:25 pm

Nonstop1h 30m

$237

DetroitSt. Louis

DTW - STL

DTWSTL

Detroit Metropolitan Wayne County

Mon 1/26

5:50 am-6:50 am

Nonstop2h 00m

Lambert-St Louis

Sat 1/31

5:45 pm-8:15 pm

Nonstop1h 30m

$237

DetroitKansas City

DTW - MCI

DTWMCI

Detroit Metropolitan Wayne County

Mon 1/26

11:00 am-4:09 pm

3 stops30h 09m

Kansas City

Mon 2/2

11:26 am-10:08 pm

2 stops9h 42m

$245

DetroitColumbia

DTW - COU

DTWCOU

Detroit Metropolitan Wayne County

Wed 1/14

11:05 am-2:35 pm

1 stop4h 30m

Columbia Regional

Sun 1/18

3:10 pm-10:10 pm

1 stop6h 00m

$268

DetroitSpringfield

DTW - SGF

DTWSGF

Detroit Metropolitan Wayne County

Thu 1/22

10:35 am-4:15 pm

1 stop6h 40m

Springfield-Branson

Thu 1/29

5:00 pm-12:44 am

1 stop6h 44m

$269

DetroitSpringfield

DTW - SGF

DTWSGF

Detroit Metropolitan Wayne County

Sat 4/18

6:00 am-11:04 am

1 stop6h 04m

Springfield-Branson

Tue 4/21

6:07 pm-11:20 pm

1 stop4h 13m

$269

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/29

Showing 1-10 of 55 results

...

Best time to book a flight from Detroit to Missouri

Have a flexible travel schedule? Discover the best time to fly to Missouri from Detroit with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Detroit to Missouri

What is the cheapest month to book a flight from Detroit to Missouri?

Currently, August is the cheapest month in which you can book a flight from Detroit to Missouri (average of $39). Flying from Detroit to Missouri in December is currently the most expensive (average of $261). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from DTT to MO?

A simple way to save on the total cost of your ticket is to fly from Detroit to Missouri at noon. If you’re flexible enough to do this you can expect to save up to 9% on your trip compared to booking a flight in the afternoon.

What is the cheapest day to fly from Detroit to Missouri?

Travelers seeking maximum savings on their Detroit to Missouri flight should consider departing on Friday at noon when fares are most often at their lowest. Monday afternoons flights should be avoided if possible as fares are typically the most expensive at this time.

Weekly flight availability from Detroit to Missouri

The most flights from DTT to USMO are scheduled on a Monday (13 on average). You will have fewer flight options on Wednesday, which is when the least amount of flights are scheduled (3 on average).

How much does it cost to fly round-trip from Detroit to Missouri?

Reviews of airlines servicing Missouri

See what other customers who have flown with Southwest, Delta, and American Airlines from Detroit to Missouri have to say. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.

Southwest

8.0

Very good

4,251 reviews

Reviews

1 / 20

2.0

Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

Southwest

8.0

Very good

4,251 reviews

Southwest

8.0

Very good

4,251 reviews

Reviews

1 / 20

2.0

Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

Delta

7.9

Good

8,013 reviews

Southwest

8.0

Very good

4,251 reviews

Reviews

1 / 20

2.0

Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

American Airlines

7.2

Good

11,074 reviews

Southwest

8.0

Very good

4,251 reviews

Reviews

1 / 20

2.0

Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

Spirit Airlines

6.3

Okay

8,245 reviews

Southwest

8.0

Very good

4,251 reviews

Reviews

1 / 20

2.0

Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

Related info for your journey

What airport do you fly from for flights from Detroit to Missouri?
If you book a flight to Missouri from Detroit, you will be flying from All airports, which is the city’s only airport. Detroit All airports (DTT) is located 0.6 mi from the center of Detroit.
How long is the flight from Detroit to Missouri?
United Airlines, Southwest, and Spirit Airlines can get you from Detroit to Missouri in just under 2h. Your travel time can differ by up to 28h 09m. The distance from Detroit to Missouri is about 439 mi. Both multi-stop and nonstop flights can be found to your destination and back.
What are the cheapest airlines to fly from Detroit to Missouri one-way?
To fly one-way, consider booking your trip with Spirit Airlines, which is currently one of the cheapest options available, starting at $36. Frontier flights start at $48 while deals on Delta start at $60 one-way.
What are the most popular routes from Detroit to Missouri?
The most popular route from Detroit to Missouri is Detroit Metropolitan Wayne County - Lambert-St Louis. You may also consider Detroit Metropolitan Wayne County - Kansas City or Detroit Metropolitan Wayne County - Springfield-Branson.
What are the most reliable airlines from Detroit to Missouri?
Consider Air France (82%), Korean Air (65%) or KLM (65%) when booking your flight. These represent the most reliable airlines when flying from Detroit to Missouri.
What are the cheapest flights from Detroit to Missouri?
While on average a flight from Detroit to Missouri is generally $349, our data shows the cheapest flight currently is $136. When looking at the most popular route, (Detroit Metropolitan Wayne County - Lambert-St Louis), you can expect to pay $160 for that flight.
Can I find deals for flights from Detroit to Missouri that include hotel bookings?
Yes. In addition to deals on Detroit to Missouri flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Detroit to Missouri?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Detroit to Missouri.
Can I find deals for business class flights from Detroit to Missouri?
Yes. Cheapflights offers flight deals from Detroit to Missouri by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Detroit to Missouri?
Currently, August is the cheapest month in which you can book a flight from Detroit to Missouri (average of $39). Flying from Detroit to Missouri in December is currently the most expensive (average of $261). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Top 6 airlines flying from Detroit to Missouri

Airline	Cheapest	Average	Flexibility	On-time
Spirit Airlines	Cheapest$36	Average$147	FlexibilityNo cancel fee	On-time65%
Frontier	Cheapest$111	Average$262	FlexibilityNo cancel fee	On-time62%
Delta	Cheapest$136	Average$373	FlexibilityNo cancel fee	On-timeN/A
Southwest	Cheapest$137	Average$404	FlexibilityNo cancel fee	On-time63%
American Airlines	Cheapest$203	Average$429	FlexibilityNo cancel fee	On-time71%
United Airlines	Cheapest$253	Average$498	FlexibilityNo cancel fee	On-time69%

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$60+ Cheap flights from Detroit (DTT) to Missouri

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/11. Fares are subject to change and may not be available on all flights or dates of travel.

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Cheap flight deals from Detroit to Missouri

Cheapest flights from Detroit to MissouriExplore the most affordable flight options available from Detroit to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 31, 2025.

Explore the most affordable flight options available from Detroit to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 31, 2025.

Find flight deals from Detroit to Missouri

Keep the following information in mind while searching for Detroit to Missouri flight deals. Data was last updated December 31, 2025.

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Best time to book a flight from Detroit to Missouri

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What is the cheapest time of day to fly from DTT to MO?

Find hourly flight availability from Detroit to Missouri. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 31, 2025.

What is the cheapest day to fly from Detroit to Missouri?

Use this chart to determine the cheapest time to fly round-trip from Detroit to Missouri. Price data was last updated on December 27, 2025.

Weekly flight availability from Detroit to Missouri

Explore weekly flight availability from Detroit to Missouri. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated December 31, 2025.

How much does it cost to fly round-trip from Detroit to Missouri?

Reviews of airlines servicing Missouri

See what other customers who have flown with Southwest, Delta, and American Airlines from Detroit to Missouri have to say. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from Detroit to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

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Top 6 airlines flying from Detroit to Missouri

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Cheapest flights from Detroit to Missouri
Explore the most affordable flight options available from Detroit to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 31, 2025.