$63+ Cheap flights from Detroit (DTT) to Missouri
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/7. Fares are subject to change and may not be available on all flights or dates of travel.
DTT — STL
May 9 — May 161
Round-trip
1 adult, Economy
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Find cheap flights from Detroit to Missouri with Cheapflights
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Cheapest flights from Detroit to MissouriExplore the most affordable flight options available from Detroit to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 9, 2026.
Explore the most affordable flight options available from Detroit to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 9, 2026.
This Kiwi.com deal was found by Cheapflights users on 4/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/16:05 pm
DTW
- STL
1 stop24h 28m
Frontier
Sat 6/65:27 pm
STL
- DTW
1 stop6h 12m
Frontier
Deal found 4/4![Frontier logo]()
$129
This Kiwi.com deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/287:04 pm
DTW
- STL
1 stop12h 46m
Frontier
Wed 4/298:23 pm
STL
- DTW
1 stop11h 42m
Frontier
Deal found 4/8![Frontier logo]()
$131
This Southwest deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/66:10 am
DTW
- MCI
1 stop4h 40m
Southwest
Wed 5/139:20 am
MCI
- DTW
1 stop5h 15m
Southwest
Deal found 4/8![Southwest logo]()
$143
This Kiwi.com deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/18:49 pm
DTW
- STL
1 stop11h 01m
Frontier
Mon 5/48:23 pm
STL
- DTW
1 stop15h 13m
Frontier
Deal found 4/7![Frontier logo]()
$144
This Kiwi.com deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/57:47 am
DTW
- STL
1 stop10h 49m
Frontier
Thu 5/76:55 pm
STL
- DTW
1 stop28h 44m
Frontier
Deal found 4/6![Frontier logo]()
$147
This Kiwi.com deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/287:04 pm
DTW
- STL
1 stop12h 46m
Frontier
Thu 4/3011:21 am
STL
- DTW
1 stop6h 34m
Frontier
Deal found 4/7![Frontier logo]()
$148
This Kiwi.com deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/57:47 am
DTW
- STL
1 stop26h 08m
Frontier
Tue 5/196:33 pm
STL
- DTW
1 stop21h 47m
Frontier
Deal found 4/6![Frontier logo]()
$158
This Kiwi.com deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/117:55 am
DTW
- STL
1 stop12h 28m
Frontier
Wed 5/135:27 pm
STL
- DTW
1 stop18h 37m
Frontier
Deal found 4/6![Frontier logo]()
$159
This Frontier deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/238:43 pm
DTW
- STL
1 stop11h 07m
Frontier
Thu 4/3011:21 am
STL
- DTW
1 stop6h 34m
Frontier
Deal found 4/7![Frontier logo]()
$160
This Kiwi.com deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/66:05 pm
DTW
- STL
1 stop23h 49m
Frontier
Wed 5/135:27 pm
STL
- DTW
1 stop6h 12m
Frontier
Deal found 4/6![Frontier logo]()
$161
This Kiwi.com deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/276:20 am
DTW
- MCI
1 stop12h 09m
Frontier
Fri 5/296:24 pm
MCI
- DTW
1 stop18h 18m
Frontier
Deal found 4/7![Frontier logo]()
$162
This Kiwi.com deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/57:47 am
DTW
- STL
1 stop26h 08m
Multiple Airlines
Sat 5/95:27 pm
STL
- DTW
1 stop13h 25m
Multiple Airlines
Deal found 4/7![Multiple Airlines logo]()
$164
Best flights from Detroit to MissouriDiscover carefully curated flight deals from Detroit to Missouri that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 9, 2026.
Discover carefully curated flight deals from Detroit to Missouri that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 9, 2026.
This Southwest deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/61:40 pm
DTW
- MCI
1 stop3h 20m
Southwest
Wed 5/135:25 am
MCI
- DTW
1 stop3h 20m
Southwest
Deal found 4/8![Southwest logo]()
$143
This Delta deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/58:02 pm
DTW
- STL
Nonstop1h 42m
Delta
Tue 5/1910:19 am
STL
- DTW
Nonstop1h 31m
Delta
Deal found 4/5![Delta logo]()
$177
This American Airlines deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/224:17 pm
DTW
- COU
1 stop7h 29m
American Airlines
Fri 5/295:19 pm
COU
- DTW
1 stop5h 23m
American Airlines
Deal found 4/7![American Airlines logo]()
$321
This United Airlines deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/236:00 am
DTW
- COU
1 stop5h 55m
United Airlines
Sat 4/258:00 am
COU
- DTW
1 stop4h 20m
United Airlines
Deal found 4/8![United Airlines logo]()
$348
This Southwest deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/67:00 am
DTW
- STL
Nonstop1h 45m
Southwest
Wed 5/1310:30 am
STL
- DTW
Nonstop1h 30m
Southwest
Deal found 4/6![Southwest logo]()
$177
This Southwest deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/67:00 am
DTW
- STL
Nonstop1h 45m
Southwest
Tue 5/125:45 am
STL
- DTW
2 stops8h 50m
Southwest
Deal found 4/6![Southwest logo]()
$192
This Delta deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/308:02 pm
DTW
- STL
Nonstop1h 42m
Delta
Mon 5/410:50 am
STL
- DTW
Nonstop1h 29m
Delta
Deal found 4/5![Delta logo]()
$213
This Southwest deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/48:15 pm
DTW
- STL
Nonstop1h 40m
Southwest
Tue 5/56:45 pm
STL
- DTW
Nonstop1h 30m
Southwest
Deal found 4/7![Southwest logo]()
$195
This Southwest deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/267:10 pm
DTW
- STL
Nonstop1h 45m
Southwest
Sun 5/3110:15 am
STL
- DTW
Nonstop1h 30m
Southwest
Deal found 4/8![Southwest logo]()
$217
This American Airlines deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/236:09 am
DTW
- COU
1 stop6h 26m
American Airlines
Mon 4/274:28 pm
COU
- DTW
1 stop5h 57m
American Airlines
Deal found 4/8![American Airlines logo]()
$348
This Southwest deal was found by Cheapflights users on 4/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/165:50 am
DTW
- STL
1 stop5h 10m
Southwest
Sun 5/1710:15 am
STL
- DTW
Nonstop1h 30m
Southwest
Deal found 4/3![Southwest logo]()
$245
This United Airlines deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/27:15 am
DTW
- SGF
1 stop4h 25m
United Airlines
Wed 5/66:22 pm
SGF
- DTW
1 stop4h 37m
United Airlines
Deal found 4/5![United Airlines logo]()
$383
This Southwest deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/158:15 pm
DTW
- STL
Nonstop1h 40m
Southwest
Sun 5/178:35 pm
STL
- DTW
Nonstop1h 30m
Southwest
Deal found 4/6![Southwest logo]()
$257
This American Airlines deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/75:00 am
DTW
- SGF
1 stop5h 51m
American Airlines
Tue 5/123:17 pm
SGF
- DTW
1 stop7h 15m
American Airlines
Deal found 4/8![American Airlines logo]()
$398
This United Airlines deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/136:18 pm
DTW
- COU
1 stop4h 43m
United Airlines
Thu 4/2311:30 am
COU
- DTW
1 stop5h 01m
United Airlines
Deal found 4/8![United Airlines logo]()
$403
This Delta deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/207:49 pm
DTW
- MCI
Nonstop2h 01m
Delta
Sun 6/2112:05 pm
MCI
- DTW
Nonstop2h 00m
Delta
Deal found 4/6![Delta logo]()
$439
This United Airlines deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/217:18 am
DTW
- COU
1 stop4h 37m
United Airlines
Sat 4/253:23 pm
COU
- DTW
1 stop5h 54m
United Airlines
Deal found 4/6![United Airlines logo]()
$408
This Delta deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/258:35 am
DTW
- MCI
Nonstop2h 04m
Delta
Sat 6/274:10 pm
MCI
- DTW
Nonstop2h 00m
Delta
Deal found 4/5![Delta logo]()
$439
This American Airlines deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/2411:57 am
DTW
- COU
2 stops10h 33m
American Airlines
Sat 4/256:00 am
COU
- DTW
2 stops7h 50m
American Airlines
Deal found 4/7![American Airlines logo]()
$442
This United Airlines deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/2510:53 am
DTW
- SGF
1 stop4h 42m
United Airlines
Sat 5/26:00 am
SGF
- DTW
2 stops12h 01m
United Airlines
Deal found 4/6![United Airlines logo]()
$419
This Delta deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/67:47 pm
DTW
- MCI
1 stop5h 08m
Delta
Sun 5/106:30 am
MCI
- DTW
Nonstop1h 58m
Delta
Deal found 4/5![Delta logo]()
$449
This United Airlines deal was found by Cheapflights users on 4/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/91:41 pm
DTW
- SGF
2 stops8h 01m
United Airlines
Mon 5/116:22 pm
SGF
- DTW
1 stop4h 37m
United Airlines
Deal found 4/4![United Airlines logo]()
$423
This American Airlines deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/266:40 am
DTW
- COU
1 stop15h 49m
American Airlines
Thu 5/286:00 am
COU
- DTW
1 stop16h 37m
American Airlines
Deal found 4/7![American Airlines logo]()
$469
This Delta deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/73:55 pm
DTW
- MCI
Nonstop2h 02m
Delta
Sun 5/106:19 am
MCI
- DTW
1 stop4h 17m
Delta
Deal found 4/5![Delta logo]()
$449
This United Airlines deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/79:39 pm
DTW
- SGF
1 stop4h 08m
United Airlines
Tue 5/126:00 am
SGF
- DTW
2 stops8h 48m
United Airlines
Deal found 4/8![United Airlines logo]()
$444
This Delta deal was found by Cheapflights users on 4/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/45:10 am
DTW
- MCI
1 stop7h 06m
Delta
Sun 6/76:25 am
MCI
- DTW
Nonstop2h 00m
Delta
Deal found 4/4![Delta logo]()
$449
This Southwest deal was found by Cheapflights users on 4/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/151:00 pm
DTW
- MCI
2 stops8h 15m
Southwest
Mon 5/184:55 pm
MCI
- DTW
1 stop3h 15m
Southwest
Deal found 4/4![Southwest logo]()
$442
This Delta deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/155:10 am
DTW
- MCI
1 stop5h 19m
Delta
Fri 5/226:30 am
MCI
- DTW
Nonstop1h 58m
Delta
Deal found 4/5![Delta logo]()
$449
This United Airlines deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/238:50 am
DTW
- SGF
1 stop6h 42m
United Airlines
Sat 5/306:00 am
SGF
- DTW
2 stops7h 34m
United Airlines
Deal found 4/5![United Airlines logo]()
$474
This Delta deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/83:55 pm
DTW
- MCI
Nonstop2h 02m
Delta
Sun 5/106:30 am
MCI
- DTW
Nonstop1h 58m
Delta
Deal found 4/8![Delta logo]()
$459
Last-minute flights from Detroit to MissouriDiscover last-minute flight deals from Detroit to Missouri. Data last updated April 9, 2026 and is based on user searches.
Discover last-minute flight deals from Detroit to Missouri. Data last updated April 9, 2026 and is based on user searches.
This Frontier deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/238:43 pm
DTW
- STL
1 stop11h 07m
Frontier
Thu 4/3011:21 am
STL
- DTW
1 stop6h 34m
Frontier
Deal found 4/7![Frontier logo]()
$160
This Kiwi.com deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/287:04 pm
DTW
- STL
1 stop12h 46m
Frontier
Wed 4/298:23 pm
STL
- DTW
1 stop11h 42m
Frontier
Deal found 4/8![Frontier logo]()
$131
This Kiwi.com deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/287:04 pm
DTW
- STL
1 stop12h 46m
Frontier
Thu 4/3011:21 am
STL
- DTW
1 stop6h 34m
Frontier
Deal found 4/7![Frontier logo]()
$148
This Kiwi.com deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/308:43 pm
DTW
- STL
1 stop11h 07m
Frontier
Mon 5/48:23 pm
STL
- DTW
1 stop27h 36m
Frontier
Deal found 4/6![Frontier logo]()
$168
This Kiwi.com deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/18:49 pm
DTW
- STL
1 stop11h 01m
Frontier
Mon 5/48:23 pm
STL
- DTW
1 stop15h 13m
Frontier
Deal found 4/7![Frontier logo]()
$144
This Kiwi.com deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/57:47 am
DTW
- STL
1 stop10h 49m
Frontier
Thu 5/76:55 pm
STL
- DTW
1 stop28h 44m
Frontier
Deal found 4/6![Frontier logo]()
$147
This Kiwi.com deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/57:47 am
DTW
- STL
1 stop26h 08m
Frontier
Tue 5/196:33 pm
STL
- DTW
1 stop21h 47m
Frontier
Deal found 4/6![Frontier logo]()
$158
This Kiwi.com deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/57:47 am
DTW
- STL
1 stop26h 08m
Multiple Airlines
Sat 5/95:27 pm
STL
- DTW
1 stop13h 25m
Multiple Airlines
Deal found 4/7![Multiple Airlines logo]()
$164
This Southwest deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/66:10 am
DTW
- MCI
1 stop4h 40m
Southwest
Wed 5/139:20 am
MCI
- DTW
1 stop5h 15m
Southwest
Deal found 4/8![Southwest logo]()
$143
This Kiwi.com deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/66:05 pm
DTW
- STL
1 stop23h 49m
Frontier
Wed 5/135:27 pm
STL
- DTW
1 stop6h 12m
Frontier
Deal found 4/6![Frontier logo]()
$161
This Kiwi.com deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/117:55 am
DTW
- STL
1 stop12h 28m
Frontier
Wed 5/135:27 pm
STL
- DTW
1 stop18h 37m
Frontier
Deal found 4/6![Frontier logo]()
$159
This Kiwi.com deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/276:20 am
DTW
- MCI
1 stop12h 09m
Frontier
Fri 5/296:24 pm
MCI
- DTW
1 stop18h 18m
Frontier
Deal found 4/7![Frontier logo]()
$162
One-way flights from Detroit to MissouriSearch for one-way flight options from Detroit to Missouri. Find affordable one-way fares based on user searches. Data last updated April 9, 2026.
Search for one-way flight options from Detroit to Missouri. Find affordable one-way fares based on user searches. Data last updated April 9, 2026.
This Kiwi.com deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/71:59 pm
DTW
- MCI
1 stop28h 30m
Frontier
Deal found 4/7![Frontier logo]()
$63
This Kiwi.com deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/26:50 am
DTW
- STL
1 stop11h 43m
Frontier
Deal found 4/6![Frontier logo]()
$65
This Kiwi.com deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/46:10 am
DTW
- MCI
1 stop12h 14m
Frontier
Deal found 4/6![Frontier logo]()
$65
This Kiwi.com deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/57:47 am
DTW
- STL
1 stop26h 08m
Frontier
Deal found 4/6![Frontier logo]()
$70
This Frontier deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/107:55 am
DTW
- MCI
1 stop6h 54m
Frontier
Deal found 4/8![Frontier logo]()
$70
This Kiwi.com deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/86:05 pm
DTW
- STL
1 stop15h 50m
Frontier
Deal found 4/6![Frontier logo]()
$71
This Southwest deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/67:40 pm
DTW
- MCI
1 stop3h 50m
Southwest
Deal found 4/8![Southwest logo]()
$72
This Frontier deal was found by Cheapflights users on 4/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/308:43 pm
DTW
- STL
1 stop11h 07m
Frontier
Deal found 4/4![Frontier logo]()
$76
This Frontier deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/66:00 am
DTW
- MCI
1 stop12h 29m
Frontier
Deal found 4/8![Frontier logo]()
$76
This Cheapflightsfares deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/115:31 pm
DTW
- MCI
1 stop7h 22m
Spirit Airlines
Deal found 4/8![Spirit Airlines logo]()
$81
This Kiwi.com deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/136:05 pm
DTW
- STL
1 stop23h 49m
Frontier
Deal found 4/6![Frontier logo]()
$82
This Kiwi.com deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/71:59 pm
DTW
- STL
1 stop19h 56m
Frontier
Deal found 4/8![Frontier logo]()
$83
Find flight deals from Detroit to Missouri
Keep the following information in mind while searching for Detroit to Missouri flight deals. Data was last updated April 9, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $126 (Kiwi.com) |
One-way from | $63 (Kiwi.com) |
Popular in | February |
Cheapest in | August |
Average price | $350 |
Good round-trip deal | $347 or less |
Good one-way deal | $208 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Detroit to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 9, 2026.
Use the filters below to find and compare flights from Detroit to Missouri that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
DetroitKansas City
DTW - MCI
DTWMCI
Detroit Metropolitan Wayne County
Wed 5/6
1:40 pm-4:00 pm
1 stop3h 20m
Kansas City
Wed 5/13
5:25 am-9:45 am
1 stop3h 20m
$143
DetroitSt. Louis
DTW - STL
DTWSTL
Detroit Metropolitan Wayne County
Tue 5/5
8:02 pm-8:44 pm
Nonstop1h 42m
Lambert-St Louis
Tue 5/19
10:19 am-12:50 pm
Nonstop1h 31m
$177
DetroitSt. Louis
DTW - STL
DTWSTL
Detroit Metropolitan Wayne County
Wed 5/6
7:00 am-7:45 am
Nonstop1h 45m
Lambert-St Louis
Wed 5/13
10:30 am-1:00 pm
Nonstop1h 30m
$177
DetroitSt. Louis
DTW - STL
DTWSTL
Detroit Metropolitan Wayne County
Wed 5/6
7:00 am-7:45 am
Nonstop1h 45m
Lambert-St Louis
Tue 5/12
5:45 am-3:35 pm
2 stops8h 50m
$192
Quickest round-trip
DetroitSt. Louis
DTW - STL
DTWSTL
Detroit Metropolitan Wayne County
Mon 5/4
8:15 pm-8:55 pm
Nonstop1h 40m
Lambert-St Louis
Tue 5/5
6:45 pm-9:15 pm
Nonstop1h 30m
$195
DetroitSt. Louis
DTW - STL
DTWSTL
Detroit Metropolitan Wayne County
Thu 4/30
8:02 pm-8:44 pm
Nonstop1h 42m
Lambert-St Louis
Mon 5/4
10:50 am-1:19 pm
Nonstop1h 29m
$213
DetroitSt. Louis
DTW - STL
DTWSTL
Detroit Metropolitan Wayne County
Tue 5/26
7:10 pm-7:55 pm
Nonstop1h 45m
Lambert-St Louis
Sun 5/31
10:15 am-12:45 pm
Nonstop1h 30m
$217
DetroitSt. Louis
DTW - STL
DTWSTL
Detroit Metropolitan Wayne County
Sat 5/16
5:50 am-10:00 am
1 stop5h 10m
Lambert-St Louis
Sun 5/17
10:15 am-12:45 pm
Nonstop1h 30m
$245
DetroitSt. Louis
DTW - STL
DTWSTL
Detroit Metropolitan Wayne County
Fri 5/15
8:15 pm-8:55 pm
Nonstop1h 40m
Lambert-St Louis
Sun 5/17
8:35 pm-11:05 pm
Nonstop1h 30m
$257
DetroitColumbia
DTW - COU
DTWCOU
Detroit Metropolitan Wayne County
Fri 5/22
4:17 pm-10:46 pm
1 stop7h 29m
Columbia Regional
Fri 5/29
5:19 pm-11:42 pm
1 stop5h 23m
$321
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from Detroit to Missouri
Have a flexible travel schedule? Discover the best time to fly to Missouri from Detroit with our price prediction graph.
DTW-MCI
DTW-STL
DTW-COU
DTW-SGF
DTW-JLN
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Detroit to Missouri
DTT-USMO
DTW-MCI
DTW-STL
DTW-COU
DTW-SGF
What is the cheapest month to book a flight from Detroit to Missouri?
Currently, August is the cheapest month in which you can book a flight from Detroit to Missouri (average of $39). Flying from Detroit to Missouri in January is currently the most expensive (average of $253). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from DTT to MO?
Find hourly flight availability from Detroit to Missouri. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 9, 2026.
A simple way to save on the total cost of your ticket is to fly from Detroit to Missouri at noon. If you’re flexible enough to do this you can expect to save up to 16% on your trip compared to booking a flight in the evening.
What is the cheapest day to fly from Detroit to Missouri?
Use this chart to determine the cheapest time to fly round-trip from Detroit to Missouri. Price data was last updated on April 4, 2026.
Travelers seeking maximum savings on their Detroit to Missouri flight should consider departing on Sunday at noon when fares are most often at their lowest. Tuesday mornings flights should be avoided if possible as fares are typically the most expensive at this time.
Weekly flight availability from Detroit to Missouri
Explore weekly flight availability from Detroit to Missouri. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated April 9, 2026.
The most flights from DTT to USMO are scheduled on a Wednesday (17 on average). You will have fewer flight options on Saturday, which is when the least amount of flights are scheduled (4 on average).
How much does it cost to fly round-trip from Detroit to Missouri?
Reviews of airlines servicing Missouri
Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated April 9, 2026.
See what other customers who have flown with Southwest,Delta, andAmerican Airlines from Detroit to Missouri have to say. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Boarding
8.1
Food
7.0
Overall
8.0
Crew
8.6
Entertainment
7.5
Comfort
8.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Boarding
8.1
Food
7.0
Overall
8.0
Crew
8.6
Entertainment
7.5
Comfort
8.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Boarding
8.1
Food
7.0
Overall
8.0
Crew
8.6
Entertainment
7.5
Comfort
8.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Boarding
8.1
Food
7.0
Overall
8.0
Crew
8.6
Entertainment
7.5
Comfort
8.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Boarding
8.1
Food
7.0
Overall
8.0
Crew
8.6
Entertainment
7.5
Comfort
8.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Related info for your journey
Find useful and relevant information for your journey from Detroit to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Detroit to Missouri
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Complete your trip
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Find flights from Detroit to Missouri, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Detroit and Missouri flights
Browse other Detroit and Missouri flight options. Last updated on April 9, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Detroit to Missouri flights
Consider these flights traveling from Detroit to Missouri.
Top 6 airlines flying from Detroit to Missouri
Discover the top 6 airlines that operate flights from Detroit to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 9, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$28 | Average$138 | FlexibilityNo cancel fee | On-time65% | |
| Cheapest$111 | Average$212 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$120 | Average$364 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$121 | Average$379 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$203 | Average$414 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$253 | Average$418 | FlexibilityNo cancel fee | On-time69% |