$49+ Cheap flights from O'Hare Intl (ORD) to Missouri
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/31. Fares are subject to change and may not be available on all flights or dates of travel.
ORD — STL
Dec 13 — Dec 201
1 adult, Economy
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Cheapest flights from O'Hare Intl to MissouriExplore the most affordable flight options available from O'Hare Intl to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 13, 2025.
Explore the most affordable flight options available from O'Hare Intl to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 13, 2025.
This Expedia deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/45:05 amORD - STL
1 stop6h 02mFrontier
Mon 12/810:47 amSTL - ORD
1 stop11h 37mFrontier
Deal found 11/11![Frontier logo]()
$120
This Mytrip deal was found by Cheapflights users on 11/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/2611:50 amORD - CGI
Nonstop1h 35mContour
Sun 11/304:05 pmCGI - ORD
Nonstop1h 40mContour
Deal found 11/12![Contour logo]()
$124
This American Airlines deal was found by Cheapflights users on 11/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/187:07 amORD - STL
Nonstop1h 28mAmerican Airlines
Sun 1/1811:05 amSTL - ORD
Nonstop1h 29mAmerican Airlines
Deal found 11/10![American Airlines logo]()
$134
This American Airlines deal was found by Cheapflights users on 11/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/810:15 pmORD - STL
Nonstop1h 23mAmerican Airlines
Wed 12/105:05 amSTL - ORD
Nonstop1h 30mAmerican Airlines
Deal found 11/13![American Airlines logo]()
$144
This Kiwi.com deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/217:00 amORD - STL
1 stop27h 02mFrontier
Mon 11/249:54 pmSTL - ORD
1 stop21h 45mFrontier
Deal found 11/11![Frontier logo]()
$156
This Delta deal was found by Cheapflights users on 11/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/311:35 pmORD - STL
1 stop7h 06mDelta
Tue 1/1312:00 pmSTL - ORD
1 stop4h 43mDelta
Deal found 11/13![Delta logo]()
$157
This eDestinos deal was found by Cheapflights users on 11/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/3112:39 pmORD - STL
1 stop21h 01mFrontier
Tue 1/135:11 pmSTL - ORD
2 stops18h 57mFrontier
Deal found 11/12![Frontier logo]()
$158
This Mytrip deal was found by Cheapflights users on 11/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/2711:50 amORD - CGI
Nonstop1h 35mContour
Mon 12/19:30 amCGI - ORD
Nonstop1h 40mContour
Deal found 11/12![Contour logo]()
$163
This Kiwi.com deal was found by Cheapflights users on 11/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/217:00 amORD - STL
1 stop27h 02mFrontier
Sun 11/2310:24 amSTL - ORD
1 stop7h 35mFrontier
Deal found 11/12![Frontier logo]()
$167
This Booking.com deal was found by Cheapflights users on 11/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/2511:50 amORD - CGI
Nonstop1h 35mContour
Mon 12/299:30 amCGI - ORD
Nonstop1h 40mContour
Deal found 11/13![Contour logo]()
$169
This United Airlines deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/42:14 pmORD - STL
Nonstop1h 26mUnited Airlines
Mon 12/811:25 amSTL - ORD
Nonstop1h 29mUnited Airlines
Deal found 11/11![United Airlines logo]()
$171
This American Airlines deal was found by Cheapflights users on 11/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/46:41 amORD - STL
Nonstop1h 27mAmerican Airlines
Mon 12/84:49 pmSTL - ORD
Nonstop1h 40mAmerican Airlines
Deal found 11/12![American Airlines logo]()
$173
Cheap flight deals from O'Hare Intl to Missouri
Keep the following information in mind while searching for O'Hare Intl to Missouri flight deals. Data was last updated November 13, 2025.
Most accurate provider | eDreams 3 stars |
|---|---|
Most trusted provider | eDreams 3 stars |
Round-trip from | $117 (American Airlines) |
One-way from | $49 (United Airlines) |
Popular in | October |
Cheapest in | August |
Average price | $318 |
Good round-trip deal | $129 or less |
Good one-way deal | $64 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from O'Hare Intl to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 13, 2025.
Use the filters below to find and compare flights from Chicago O'Hare Intl Airport to Missouri that are best for you.
Fly from
O'Hare Intl
Fly to
Missouri
Route
Depart
Return
Price
ChicagoCape Girardeau
ORD - CGI
ORDCGI
Chicago O'Hare Intl
Wed 11/26
11:50 am-1:25 pm
Nonstop1h 35m
Cape Girardeau
Sun 11/30
4:05 pm-5:45 pm
Nonstop1h 40m
$124
ChicagoSt. Louis
ORD - STL
ORDSTL
Chicago O'Hare Intl
Wed 4/1
2:40 pm-7:55 pm
1 stop5h 15m
Lambert-St Louis
Wed 4/8
6:35 am-3:00 pm
1 stop8h 25m
$137
ChicagoSt. Louis
ORD - STL
ORDSTL
Chicago O'Hare Intl
Tue 12/30
10:12 am-10:33 pm
1 stop12h 21m
Lambert-St Louis
Thu 1/1
10:42 am-10:24 pm
1 stop11h 42m
$156
ChicagoSt. Louis
ORD - STL
ORDSTL
Chicago O'Hare Intl
Wed 12/31
1:35 pm-8:41 pm
1 stop7h 06m
Lambert-St Louis
Tue 1/13
12:00 pm-7:35 pm
1 stop7h 35m
$157
ChicagoSt. Louis
ORD - STL
ORDSTL
Chicago O'Hare Intl
Tue 3/31
7:00 pm-11:10 pm
1 stop4h 10m
Lambert-St Louis
Tue 4/7
5:30 pm-9:56 pm
1 stop4h 26m
$157
ChicagoCape Girardeau
ORD - CGI
ORDCGI
Chicago O'Hare Intl
Thu 11/27
11:50 am-1:25 pm
Nonstop1h 35m
Cape Girardeau
Mon 12/1
9:30 am-11:10 am
Nonstop1h 40m
$163
ChicagoSt. Louis
ORD - STL
ORDSTL
Chicago O'Hare Intl
Mon 2/9
1:45 pm-8:10 pm
1 stop6h 25m
Lambert-St Louis
Wed 2/11
8:15 am-12:15 pm
1 stop4h 00m
$164
ChicagoCape Girardeau
ORD - CGI
ORDCGI
Chicago O'Hare Intl
Thu 12/25
11:50 am-1:25 pm
Nonstop1h 35m
Cape Girardeau
Mon 12/29
9:30 am-11:10 am
Nonstop1h 40m
$169
ChicagoSt. Louis
ORD - STL
ORDSTL
Chicago O'Hare Intl
Mon 12/8
5:59 pm-11:42 pm
1 stop5h 43m
Lambert-St Louis
Wed 12/10
5:28 pm-10:46 pm
1 stop5h 18m
$174
ChicagoColumbia
ORD - COU
ORDCOU
Chicago O'Hare Intl
Thu 1/15
1:00 pm-2:35 pm
Nonstop1h 35m
Columbia Regional
Sat 1/17
8:09 am-9:55 am
Nonstop1h 46m
$179
Showing 1-10 of 60 results
Best time to book a flight from O'Hare Intl to Missouri
Have a flexible travel schedule? Discover the best time to fly to Missouri from O'Hare Intl with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Chicago O'Hare Intl Airport to Missouri
What is the cheapest month to book a flight from Chicago O'Hare Intl Airport to Missouri?
Currently, September is the cheapest month in which you can book a flight from Chicago O'Hare Intl Airport to Missouri (average of $79). Flying from Chicago O'Hare Intl Airport to Missouri in February is currently the most expensive (average of $160). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from ORD to MO?
Find hourly flight availability from O'Hare Intl to Missouri. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated November 13, 2025.
Unlike in the afternoon, when flights are generally more expensive, you can save up to 20% on flights from Chicago O'Hare Intl Airport to Missouri by exploring options for tickets in the morning.
What is the cheapest day to fly from Chicago O'Hare Intl Airport to Missouri?
Use this chart to determine the cheapest time to fly round-trip from O'Hare Intl to Missouri. Price data was last updated on December 16, 2024.
Travelers seeking maximum savings on their Chicago O'Hare Intl Airport to Missouri flight should consider departing on Friday afternoons when fares are most often at their lowest. Saturday afternoons flights should be avoided if possible as fares are typically the most expensive at this time.
Weekly flight availability from Chicago O'Hare Intl Airport to Missouri
Explore weekly flight availability from O'Hare Intl to Missouri. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated November 13, 2025.
The most flights from ORD to USMO are scheduled on a Thursday (60 on average). You will have fewer flight options on Tuesday, which is when the least amount of flights are scheduled (42 on average).
Reviews of airlines servicing Missouri
Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated November 13, 2025.
Peruse reviews from past customers who have flown with Contour, United Airlines, and American Airlines from Chicago O'Hare Intl Airport to Missouri to help guide your decision. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Crew
7.9
Overall
7.5
Food
6.9
Comfort
7.3
Boarding
7.5
Entertainment
6.3
Reviews
1 / 2
10.0
ExcellentAnonymous,Oct 2025
CLT - PAH
Crew
7.9
Overall
7.5
Food
6.9
Comfort
7.3
Boarding
7.5
Entertainment
6.3
Reviews
1 / 2
10.0
ExcellentAnonymous,Oct 2025
CLT - PAH
Crew
7.9
Overall
7.5
Food
6.9
Comfort
7.3
Boarding
7.5
Entertainment
6.3
Reviews
1 / 2
10.0
ExcellentAnonymous,Oct 2025
CLT - PAH
Crew
7.9
Overall
7.5
Food
6.9
Comfort
7.3
Boarding
7.5
Entertainment
6.3
Reviews
1 / 2
10.0
ExcellentAnonymous,Oct 2025
CLT - PAH
Crew
7.9
Overall
7.5
Food
6.9
Comfort
7.3
Boarding
7.5
Entertainment
6.3
Reviews
1 / 2
10.0
ExcellentAnonymous,Oct 2025
CLT - PAH
Related info for your journey
Find useful and relevant information for your journey from O'Hare Intl to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for O'Hare Intl to Missouri
See prices for flight routes from nearby airports that may be better suited for you.
Top 4 airlines flying from O'Hare Intl to Missouri
Discover the top 4 airlines that operate flights from O'Hare Intl to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 13, 2025.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$114 | Average$182 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$115 | Average$329 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$145 | Average$214 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$152 | Average$323 | FlexibilityNo cancel fee | On-time69% |