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$263+ Cheap flights from the Cayman Islands to Missouri

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/23. Fares are subject to change and may not be available on all flights or dates of travel.
GCM — STL
Jun 28 — Jul 51
Sat 6/28
Sat 7/5
1 adult, Economy
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Find flight deals from Cayman Islands to Missouri

One-way flights from Cayman Islands to Missouri
Search for one-way flight options from Cayman Islands to Missouri. Find affordable one-way fares based on user searches. Data last updated June 23, 2025.

This Delta deal was found by Cheapflights users on 6/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/231:02 pmGCM - MCI
1 stop9h 19mDelta
Deal found 6/21$263
This American Airlines deal was found by Cheapflights users on 6/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/2212:15 pmGCM - MCI
1 stop11h 17mAmerican Airlines
Deal found 6/21$268
This United Airlines deal was found by Cheapflights users on 6/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/191:35 pmGCM - MCI
2 stops32h 10mUnited Airlines
Deal found 6/21$321
This Kiwi.com deal was found by Cheapflights users on 6/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/227:00 amGCM - MCI
3 stops15h 57mMultiple Airlines
Deal found 6/21$1,538

Cheapflights Fare Finder

Customize your flight search to find flights from Cayman Islands to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 23, 2025.
Use the filters below to find and compare flights from the Cayman Islands to Missouri that are best for you.

Fly from

Cayman Islands

Fly to

Missouri

Route

Depart

Return

Price

George TownKansas City

GCM - MCI

GCMMCI

George Town Owen Roberts Intl

Thu 10/23

1:02 pm-10:21 pm

1 stop9h 19m

$263

George TownKansas City

GCM - MCI

GCMMCI

George Town Owen Roberts Intl

Wed 10/22

12:15 pm-11:32 pm

1 stop11h 17m

$268

George TownKansas City

GCM - MCI

GCMMCI

George Town Owen Roberts Intl

Sun 10/19

1:35 pm-9:45 pm

2 stops32h 10m

$321

George TownKansas City

GCM - MCI

GCMMCI

George Town Owen Roberts Intl

Wed 10/22

7:00 am-10:57 pm

3 stops15h 57m

$1,538

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/21

Best time to book a flight from Cayman Islands to Missouri

Have a flexible travel schedule? Discover the best time to fly to Missouri from Cayman Islands with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from the Cayman Islands to Missouri

Rainfall in Missouri by month

Plan your trip to Missouri by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Missouri ranges from 1.1 - 5.2 inches per month. May is typically the wettest month, when rainfall can reach 5.2 in. January is typically the driest time to visit Missouri when rainfall is around 1.1 in.

Temperature in Missouri by month

Plan your trip to Missouri by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Missouri, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 78.8 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 28.4 F).

Reviews of airlines servicing Missouri

Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated June 23, 2025.
Delta
8.0
Very good
7,962 reviews

Entertainment

7.9

Crew

8.5

Boarding

8.2

Food

7.3

Overall

8.0

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Delta
8.0
Very good
7,962 reviews
Delta
8.0
Very good
7,962 reviews

Entertainment

7.9

Crew

8.5

Boarding

8.2

Food

7.3

Overall

8.0

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
United Airlines
7.4
Good
8,830 reviews
Delta
8.0
Very good
7,962 reviews

Entertainment

7.9

Crew

8.5

Boarding

8.2

Food

7.3

Overall

8.0

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,962 reviews

Entertainment

7.9

Crew

8.5

Boarding

8.2

Food

7.3

Overall

8.0

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

Find useful and relevant information for your journey from Cayman Islands to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines to fly from Cayman Islands to Missouri one-way?

    For one-way options, check prices for Delta. According to our data, you can fly for as low as $263. Users have also found prices from $268 and $321 on American Airlines and United Airlines, respectively.

  • Can I find deals for flights from Cayman Islands to Missouri that include hotel bookings?

    Yes. In addition to deals on Cayman Islands to Missouri flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Cayman Islands to Missouri?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Cayman Islands to Missouri.

  • Can I find deals for business class flights from Cayman Islands to Missouri?

    Yes. Cheapflights offers flight deals from Cayman Islands to Missouri by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Cayman Islands to Missouri?

    Currently, August is the cheapest month in which you can book a flight from Cayman Islands to Missouri (average of $311). Flying from Cayman Islands to Missouri in March is currently the most expensive (average of $356). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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