$359+ Cheap flights from Knoxville to Missoula (TYS - MSO)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/30. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — MSO
Oct 6 — Oct 131
Round-trip
1 adult, Economy
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Find cheap flights from Knoxville to Missoula with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Knoxville to Missoula
Cheapest
Best
Last-minute
Cheapest flights from Knoxville to MissoulaExplore the most affordable flight options available from Knoxville to Missoula. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 6, 2026.
Explore the most affordable flight options available from Knoxville to Missoula. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 6, 2026.
This American Airlines deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/306:00 am -
1 stop9h 18m
Tue 11/31:06 pm -
1 stop7h 45m
Deal found 9/2![American Airlines logo]()
$359
This United Airlines deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/226:00 am -
2 stops11h 24m
Sat 9/266:15 am -
1 stop7h 39m
Deal found 9/3![United Airlines logo]()
$399
This United Airlines deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/184:50 pm -
1 stop6h 44m
Tue 9/226:15 am -
1 stop7h 39m
Deal found 9/3![United Airlines logo]()
$429
This United Airlines deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/64:50 pm -
1 stop6h 41m
Sat 9/126:15 am -
1 stop7h 31m
Deal found 9/5![United Airlines logo]()
$561
This American Airlines deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/27:19 am -
1 stop7h 16m
Sun 9/61:25 pm -
1 stop6h 28m
Deal found 9/1![American Airlines logo]()
$589
This United Airlines deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/21:00 pm -
2 stops10h 31m
Sun 9/62:40 pm -
1 stop5h 49m
Deal found 9/1![United Airlines logo]()
$594
Best flights from Knoxville to MissoulaDiscover carefully curated flight deals from Knoxville to Missoula that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 6, 2026.
Discover carefully curated flight deals from Knoxville to Missoula that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 6, 2026.
This American Airlines deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/306:00 am -
1 stop9h 18m
Tue 11/31:06 pm -
1 stop7h 45m
Deal found 9/2![American Airlines logo]()
$359
This United Airlines deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/226:00 am -
2 stops11h 24m
Sat 9/266:15 am -
1 stop7h 39m
Deal found 9/3![United Airlines logo]()
$399
This Delta deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/305:40 am -
2 stops8h 54m
Tue 11/35:30 am -
2 stops12h 19m
Deal found 9/2![Delta logo]()
$399
This United Airlines deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/184:50 pm -
1 stop6h 44m
Tue 9/226:15 am -
1 stop7h 39m
Deal found 9/3![United Airlines logo]()
$429
This United Airlines deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/304:25 pm -
1 stop7h 01m
Tue 2/26:15 am -
1 stop6h 21m
Deal found 9/1![United Airlines logo]()
$459
This United Airlines deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/304:25 pm -
1 stop7h 01m
Wed 2/36:15 am -
1 stop6h 21m
Deal found 9/2![United Airlines logo]()
$459
Last-minute flights from Knoxville to MissoulaDiscover last-minute flight deals from Knoxville to Missoula. Data last updated September 6, 2026 and is based on user searches.
Discover last-minute flight deals from Knoxville to Missoula. Data last updated September 6, 2026 and is based on user searches.
This United Airlines deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/64:50 pm -
1 stop6h 41m
Sat 9/126:15 am -
1 stop7h 31m
Deal found 9/5![United Airlines logo]()
$561
This United Airlines deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/184:50 pm -
1 stop6h 44m
Tue 9/226:15 am -
1 stop7h 39m
Deal found 9/3![United Airlines logo]()
$429
This United Airlines deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/226:00 am -
2 stops11h 24m
Sat 9/266:15 am -
1 stop7h 39m
Deal found 9/3![United Airlines logo]()
$399
This American Airlines deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/226:00 am -
1 stop8h 11m
Sat 9/2612:45 pm -
1 stop7h 57m
Deal found 9/3![American Airlines logo]()
$683
This United Airlines deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/34:53 pm -
1 stop6h 39m
Sat 10/1012:28 pm -
1 stop6h 21m
Deal found 9/5![United Airlines logo]()
$717
This American Airlines deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/306:00 am -
1 stop9h 18m
Tue 11/31:06 pm -
1 stop7h 45m
Deal found 9/2![American Airlines logo]()
$359
Find flight deals from Knoxville to Missoula
Discover tips and strategies to find the most affordable flight options for your journey from Knoxville (TYS) to Missoula (MSO). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 6, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $359 (American Airlines) |
Cheapflights Fare Finder
Customize your flight search to find flights from Knoxville to Missoula that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 6, 2026.
Use the filters below to find and compare flights from Knoxville to Missoula that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
KnoxvilleMissoula
TYS Knoxville McGhee Tyson - MSO Missoula Johnson-Bell Field
TYSMSO
Knoxville McGhee Tyson
Fri 10/30
6:00 am-1:18 pm
1 stop9h 18m
Missoula Johnson-Bell Field
Tue 11/3
1:06 pm-10:51 pm
1 stop7h 45m
$359
KnoxvilleMissoula
TYS Knoxville McGhee Tyson - MSO Missoula Johnson-Bell Field
TYSMSO
Knoxville McGhee Tyson
Tue 9/22
6:00 am-3:24 pm
2 stops11h 24m
Missoula Johnson-Bell Field
Sat 9/26
6:15 am-3:54 pm
1 stop7h 39m
$399
KnoxvilleMissoula
TYS Knoxville McGhee Tyson - MSO Missoula Johnson-Bell Field
TYSMSO
Knoxville McGhee Tyson
Fri 10/30
5:40 am-12:34 pm
2 stops8h 54m
Missoula Johnson-Bell Field
Tue 11/3
5:30 am-7:49 pm
2 stops12h 19m
$399
KnoxvilleMissoula
TYS Knoxville McGhee Tyson - MSO Missoula Johnson-Bell Field
TYSMSO
Knoxville McGhee Tyson
Fri 9/18
4:50 pm-9:34 pm
1 stop6h 44m
Missoula Johnson-Bell Field
Tue 9/22
6:15 am-3:54 pm
1 stop7h 39m
$429
Quickest round-trip
KnoxvilleMissoula
TYS Knoxville McGhee Tyson - MSO Missoula Johnson-Bell Field
TYSMSO
Knoxville McGhee Tyson
Sat 1/30
4:25 pm-9:26 pm
1 stop7h 01m
Missoula Johnson-Bell Field
Tue 2/2
6:15 am-2:36 pm
1 stop6h 21m
$459
KnoxvilleMissoula
TYS Knoxville McGhee Tyson - MSO Missoula Johnson-Bell Field
TYSMSO
Knoxville McGhee Tyson
Sat 1/30
4:25 pm-9:26 pm
1 stop7h 01m
Missoula Johnson-Bell Field
Wed 2/3
6:15 am-2:36 pm
1 stop6h 21m
$459
Sorted by cheapest first
Compare providers for flights from Knoxville to Missoula
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Knoxville to Missoula in September.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Knoxville-Missoula flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Knoxville-Missoula flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Knoxville-Missoula flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Knoxville-Missoula flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Knoxville-Missoula flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Knoxville to Missoula
Have a flexible travel schedule? Discover the best time to fly to Missoula from Knoxville with our price prediction graph.
TYS-MSO
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Reviews of airlines servicing Missoula
Get insights into the airlines that provide service to Missoula. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missoula. Reviews last updated September 6, 2026.
Read reviews from past customers who have flown United Airlines from Knoxville to Missoula. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
7.1
Overall
7.4
Boarding
7.7
Food
6.6
Crew
8.1
Comfort
7.3
Reviews
1 / 20
4.0
OkayChris,Aug 2026
MIA - ORD
Entertainment
7.1
Overall
7.4
Boarding
7.7
Food
6.6
Crew
8.1
Comfort
7.3
Reviews
1 / 20
4.0
OkayChris,Aug 2026
MIA - ORD
Related info for your journey
Find useful and relevant information for your journey from Knoxville to Missoula. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Top airline flying from Knoxville to Missoula
Discover the top airline that operate flights from Knoxville to Missoula. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 6, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$364 | Average$543 | FlexibilityNo cancel fee | On-time69% |