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Missoula

$228+ Cheap flights from Knoxville to Missoula (TYS - MSO)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/20. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — MSO
Apr 22 — Apr 291
Wed 4/22
Wed 4/29
1 adult, Economy
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Cheap flight deals from Knoxville to Missoula

Cheapest flights from Knoxville to Missoula
Explore the most affordable flight options available from Knoxville to Missoula. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 23, 2026.

This Delta deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/236:15 pm
TYS
-
MSO
1 stop7h 32m
Delta
Sun 8/305:45 am
MSO
-
TYS
1 stop8h 49m
Delta
Deal found 3/22$369
This American Airlines deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/74:09 pm
TYS
-
MSO
1 stop7h 36m
American Airlines
Tue 4/146:45 am
MSO
-
TYS
1 stop6h 33m
American Airlines
Deal found 3/20$394
This Delta deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/174:00 pm
TYS
-
MSO
2 stops10h 31m
Delta
Sat 10/246:10 pm
MSO
-
TYS
2 stops13h 02m
Delta
Deal found 3/21$404
This United Airlines deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/174:25 pm
TYS
-
MSO
1 stop7h 01m
United Airlines
Sat 10/2410:30 am
MSO
-
TYS
2 stops12h 00m
United Airlines
Deal found 3/21$453
This United Airlines deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/256:30 am
TYS
-
MSO
1 stop7h 04m
United Airlines
Sat 8/2912:40 pm
MSO
-
TYS
1 stop6h 08m
United Airlines
Deal found 3/19$469

Find flight deals from Knoxville to Missoula

Discover tips and strategies to find the most affordable flight options for your journey from Knoxville (TYS) to Missoula (MSO). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated March 23, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$369
(Delta)

One-way from

$228
(Kiwi.com)

Popular in

May

Cheapest in

January

Average price

$336
Provider with most accurate pricing for Knoxville McGhee Tyson-Missoula Johnson-Bell Field flight deals.
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Provider most trusted by Cheapflights users for Knoxville McGhee Tyson-Missoula Johnson-Bell Field flights.
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From Knoxville McGhee Tyson to Missoula Johnson-Bell Field
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One-way flight from Knoxville McGhee Tyson to Missoula Johnson-Bell Field
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Highest demand for flights based on searches. 28% potential increase in price ($175 potential increase over avg. RT price).
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Cheapest flight prices on average. 7% potential price decrease ($30 potential savings vs. average RT price).
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Average for round-trip flights in March 2026
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Knoxville to Missoula that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 23, 2026.
Use the filters below to find and compare flights from Knoxville to Missoula that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

KnoxvilleMissoula

TYS - MSO

TYSMSO

Knoxville McGhee Tyson

Tue 4/7

4:09 pm-9:45 pm

1 stop7h 36m

Missoula Johnson-Bell Field

Tue 4/14

6:45 am-3:18 pm

1 stop6h 33m

$394
Quickest round-trip

KnoxvilleMissoula

TYS - MSO

TYSMSO

Knoxville McGhee Tyson

Tue 8/25

6:30 am-11:34 am

1 stop7h 04m

Missoula Johnson-Bell Field

Sat 8/29

12:40 pm-8:48 pm

1 stop6h 08m

$469

KnoxvilleMissoula

TYS - MSO

TYSMSO

Knoxville McGhee Tyson

Wed 6/10

6:30 am-11:32 am

1 stop7h 02m

Missoula Johnson-Bell Field

Wed 6/17

12:33 pm-8:56 pm

1 stop6h 23m

$510

KnoxvilleMissoula

TYS - MSO

TYSMSO

Knoxville McGhee Tyson

Tue 4/7

5:24 pm-12:24 am

2 stops9h 00m

Missoula Johnson-Bell Field

Tue 4/14

6:18 pm-9:22 am

2 stops13h 04m

$519
Cheapest one-way

KnoxvilleMissoula

TYS - MSO

TYSMSO

Knoxville McGhee Tyson

Mon 4/20

1:43 pm-8:04 pm

1 stop8h 21m

$228
Quickest one-way

KnoxvilleMissoula

TYS - MSO

TYSMSO

Knoxville McGhee Tyson

Mon 7/6

6:30 am-11:32 am

1 stop7h 02m

$257

KnoxvilleMissoula

TYS - MSO

TYSMSO

Knoxville McGhee Tyson

Mon 7/6

5:36 am-4:11 pm

2 stops12h 35m

$436

KnoxvilleMissoula

TYS - MSO

TYSMSO

Knoxville McGhee Tyson

Mon 4/20

1:43 pm-12:31 pm

3 stops24h 48m

$565

KnoxvilleMissoula

TYS - MSO

TYSMSO

Knoxville McGhee Tyson

Sat 4/11

4:09 pm-9:45 pm

1 stop7h 36m

$566

KnoxvilleMissoula

TYS - MSO

TYSMSO

Knoxville McGhee Tyson

Sun 4/26

8:48 pm-12:38 pm

1 stop17h 50m

$669

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/18

Showing 1-10 of 13 resultsSorted by cheapest first
1
2

Compare providers for flights from Knoxville to Missoula

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Knoxville to Missoula in March.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Knoxville-Missoula flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Knoxville-Missoula flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Knoxville-Missoula flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Knoxville-Missoula flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Knoxville-Missoula flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Knoxville to Missoula

Have a flexible travel schedule? Discover the best time to fly to Missoula from Knoxville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Knoxville to Missoula

What’s the top layover airport for flights from Knoxville to Missoula?

Share of 1-stop round-trip flights from Knoxville to Missoula chosen by Cheapflights users in the past 12 months, using the same layover each way.

Chicago (ORD) – chosen by Cheapflights users on 86% of 1-stop itineraries from Knoxville to Missoula on Cheapflights.

What’s the cheapest layover airport for flights from Knoxville to Missoula?

Average round-trip fare for 1-stop flights from Knoxville to Missoula, chosen by Cheapflights users in the past 12 months, with the same layover each way.

Chicago (ORD) is the most affordable 1-stop option, with an average round-trip price of $425.

What’s the fastest layover option from Knoxville to Missoula?

Shortest average travel time for 1-stop one-way flights from Knoxville to Missoula, based on itineraries clicked by Cheapflights users over the past 12 months, grouped by layover airport.

Flights via Denver (DEN) have the shortest average one-way travel time for 1-stop routes: 6h 30m.

Which airport typically offers the quickest layover for flights from Knoxville to Missoula?

Average layover duration for 1-stop one-way flights from Knoxville to Missoula, chosen by Cheapflights users in the last 12 months, grouped by stopover airport.

Flights via Chicago (ORD) offer the fastest connection on this route, with an average layover time of 1h 50m.

Reviews of airlines servicing Missoula

Get insights into the airlines that provide service to Missoula. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missoula. Reviews last updated March 23, 2026.
Read reviews from past customers who have flown United Airlines and American Airlines from Knoxville to Missoula. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
United Airlines
7.4
Good
9,461 reviews

Overall

7.4

Crew

8.1

Food

6.6

Entertainment

7.1

Boarding

7.7

Comfort

7.3

Reviews

1 / 20
10.0
Excellent

Dane,Jan 2026

TYS - IAD

It was a short flight, so no time for amenities. Just glad everything was quick and easy from boarding to arriving at my destination with my family
United Airlines
7.4
Good
9,461 reviews
United Airlines
7.4
Good
9,461 reviews

Overall

7.4

Crew

8.1

Food

6.6

Entertainment

7.1

Boarding

7.7

Comfort

7.3

Reviews

1 / 20
10.0
Excellent

Dane,Jan 2026

TYS - IAD

It was a short flight, so no time for amenities. Just glad everything was quick and easy from boarding to arriving at my destination with my family
American Airlines
7.1
Good
11,489 reviews
United Airlines
7.4
Good
9,461 reviews

Overall

7.4

Crew

8.1

Food

6.6

Entertainment

7.1

Boarding

7.7

Comfort

7.3

Reviews

1 / 20
10.0
Excellent

Dane,Jan 2026

TYS - IAD

It was a short flight, so no time for amenities. Just glad everything was quick and easy from boarding to arriving at my destination with my family

Related info for your journey

Find useful and relevant information for your journey from Knoxville to Missoula. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Knoxville to Missoula?

    Airlines like American Airlines fly from Knoxville to Missoula in about 7h 36m. The time it takes to get you to your destination can typically vary by up to . There are 1724 mi between Knoxville and Missoula.

  • What are the cheapest airlines flying from Knoxville to Missoula round-trip?

    American Airlines, at $288, was found to be the cheapest airline from Knoxville to Missoula. An alternate airline flying to your destination would be United Airlines. You may be able to fly from Knoxville to Missoula for 33% less than the average price by searching for these airlines.

  • Can I find deals for flights from Knoxville to Missoula that include hotel bookings?

    Yes. In addition to deals on Knoxville to Missoula flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to Missoula?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Missoula.

  • Can I find deals for business class flights from Knoxville to Missoula?

    Yes. Cheapflights offers flight deals from Knoxville to Missoula by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Top 2 airlines flying from Knoxville to Missoula

Discover the top 2 airlines that operate flights from Knoxville to Missoula. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 23, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$288Average$418FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$356Average$543FlexibilityNo cancel feeOn-time69%

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