$291+ Cheap flights from Knoxville to Missoula (TYS - MSO)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/11. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — MSO
Nov 6 — Nov 131
Round-trip
1 adult, Economy
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Find cheap flights from Knoxville to Missoula with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Knoxville to Missoula
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Best
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One-way
Cheapest flights from Knoxville to MissoulaExplore the most affordable flight options available from Knoxville to Missoula. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 7, 2026.
Explore the most affordable flight options available from Knoxville to Missoula. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 7, 2026.
This United Airlines deal was found by Cheapflights users on 10/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/45:05 pm -
1 stop6h 42m
Tue 11/106:15 am -
1 stop6h 46m
Deal found 10/4![United Airlines logo]()
$379
This United Airlines deal was found by Cheapflights users on 10/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/239:00 am -
1 stop6h 32m
Wed 10/286:15 am -
1 stop6h 46m
Deal found 10/6![United Airlines logo]()
$414
This Delta deal was found by Cheapflights users on 10/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/2311:45 am -
2 stops10h 09m
Wed 10/285:30 am -
2 stops9h 58m
Deal found 10/6![Delta logo]()
$425
This United Airlines deal was found by Cheapflights users on 10/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/216:00 am -
1 stop7h 32m
Mon 10/262:37 pm -
1 stop5h 55m
Deal found 10/6![United Airlines logo]()
$449
This United Airlines deal was found by Cheapflights users on 10/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/219:00 am -
1 stop6h 32m
Sun 10/252:37 pm -
1 stop5h 55m
Deal found 10/6![United Airlines logo]()
$482
This United Airlines deal was found by Cheapflights users on 10/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/236:00 am -
1 stop7h 32m
Fri 10/302:37 pm -
1 stop5h 55m
Deal found 10/2![United Airlines logo]()
$499
This Delta deal was found by Cheapflights users on 10/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/212:38 pm -
2 stops11h 53m
Mon 10/265:30 am -
2 stops7h 56m
Deal found 10/6![Delta logo]()
$504
Best flights from Knoxville to MissoulaDiscover carefully curated flight deals from Knoxville to Missoula that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 7, 2026.
Discover carefully curated flight deals from Knoxville to Missoula that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 7, 2026.
This American Airlines deal was found by Cheapflights users on 10/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/47:52 am -
1 stop6h 44m
Tue 11/101:06 pm -
1 stop7h 45m
Deal found 10/4![American Airlines logo]()
$379
This United Airlines deal was found by Cheapflights users on 10/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/239:00 am -
1 stop6h 32m
Wed 10/286:15 am -
1 stop6h 46m
Deal found 10/6![United Airlines logo]()
$414
This United Airlines deal was found by Cheapflights users on 10/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/216:00 am -
2 stops11h 19m
Sun 10/252:37 pm -
1 stop5h 55m
Deal found 10/6![United Airlines logo]()
$488
This United Airlines deal was found by Cheapflights users on 10/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/236:00 am -
1 stop7h 32m
Fri 10/302:37 pm -
1 stop5h 55m
Deal found 10/2![United Airlines logo]()
$499
This United Airlines deal was found by Cheapflights users on 10/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/304:28 pm -
1 stop7h 24m
Tue 2/26:10 am -
1 stop6h 45m
Deal found 10/6![United Airlines logo]()
$499
Last-minute flights from Knoxville to MissoulaDiscover last-minute flight deals from Knoxville to Missoula. Data last updated October 7, 2026 and is based on user searches.
Discover last-minute flight deals from Knoxville to Missoula. Data last updated October 7, 2026 and is based on user searches.
This United Airlines deal was found by Cheapflights users on 10/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/216:00 am -
1 stop7h 32m
Mon 10/262:37 pm -
1 stop5h 55m
Deal found 10/6![United Airlines logo]()
$449
This United Airlines deal was found by Cheapflights users on 10/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/219:00 am -
1 stop6h 32m
Sun 10/252:37 pm -
1 stop5h 55m
Deal found 10/6![United Airlines logo]()
$482
This Delta deal was found by Cheapflights users on 10/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/212:38 pm -
2 stops11h 53m
Mon 10/265:30 am -
2 stops7h 56m
Deal found 10/6![Delta logo]()
$504
This United Airlines deal was found by Cheapflights users on 10/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/239:00 am -
1 stop6h 32m
Wed 10/286:15 am -
1 stop6h 46m
Deal found 10/6![United Airlines logo]()
$414
This Delta deal was found by Cheapflights users on 10/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/2311:45 am -
2 stops10h 09m
Wed 10/285:30 am -
2 stops9h 58m
Deal found 10/6![Delta logo]()
$425
This United Airlines deal was found by Cheapflights users on 10/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/236:00 am -
1 stop7h 32m
Fri 10/302:37 pm -
1 stop5h 55m
Deal found 10/2![United Airlines logo]()
$499
This United Airlines deal was found by Cheapflights users on 10/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/45:05 pm -
1 stop6h 42m
Tue 11/106:15 am -
1 stop6h 46m
Deal found 10/4![United Airlines logo]()
$379
One-way flights from Knoxville to MissoulaSearch for one-way flight options from Knoxville to Missoula. Find affordable one-way fares based on user searches. Data last updated October 7, 2026.
Search for one-way flight options from Knoxville to Missoula. Find affordable one-way fares based on user searches. Data last updated October 7, 2026.
This American Airlines deal was found by Cheapflights users on 10/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/112:55 pm -
1 stop7h 42m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/5![American Airlines logo]()
$291
This Delta deal was found by Cheapflights users on 10/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/115:10 pm -
2 stops9h 27m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/5![Delta logo]()
$296
This Kiwi.com deal was found by Cheapflights users on 10/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/119:49 pm -
3 stops46h 49m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/5![Multiple Airlines logo]()
$362
This Kiwi.com deal was found by Cheapflights users on 10/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/2910:03 pm -
3 stops22h 38m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/5![Multiple Airlines logo]()
$588
This American Airlines deal was found by Cheapflights users on 10/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/298:50 pm -
1 stop17h 58m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/5![American Airlines logo]()
$888
Find flight deals from Knoxville to Missoula
Discover tips and strategies to find the most affordable flight options for your journey from Knoxville (TYS) to Missoula (MSO). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated October 7, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $379 (United Airlines) |
One-way from | $291 (American Airlines) |
Cheapflights Fare Finder
Customize your flight search to find flights from Knoxville to Missoula that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 7, 2026.
Use the filters below to find and compare flights from Knoxville to Missoula that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Quickest round-trip
KnoxvilleMissoula
TYS Knoxville McGhee Tyson - MSO Missoula Johnson-Bell Field
TYSMSO
Knoxville McGhee Tyson
Fri 12/11
2:55 pm-8:37 pm
1 stop7h 42m
Missoula Johnson-Bell Field
Wed 12/31
12:00 am-2:00 am
Nonstop0h 00m
$291
KnoxvilleMissoula
TYS Knoxville McGhee Tyson - MSO Missoula Johnson-Bell Field
TYSMSO
Knoxville McGhee Tyson
Fri 12/11
5:10 pm-12:37 am
2 stops9h 27m
Missoula Johnson-Bell Field
Wed 12/31
12:00 am-2:00 am
Nonstop0h 00m
$296
KnoxvilleMissoula
TYS Knoxville McGhee Tyson - MSO Missoula Johnson-Bell Field
TYSMSO
Knoxville McGhee Tyson
Fri 12/11
9:49 pm-6:38 pm
3 stops46h 49m
Missoula Johnson-Bell Field
Wed 12/31
12:00 am-2:00 am
Nonstop0h 00m
$362
KnoxvilleMissoula
TYS Knoxville McGhee Tyson - MSO Missoula Johnson-Bell Field
TYSMSO
Knoxville McGhee Tyson
Wed 11/4
7:52 am-12:36 pm
1 stop6h 44m
Missoula Johnson-Bell Field
Tue 11/10
1:06 pm-10:51 pm
1 stop7h 45m
$379
KnoxvilleMissoula
TYS Knoxville McGhee Tyson - MSO Missoula Johnson-Bell Field
TYSMSO
Knoxville McGhee Tyson
Fri 10/23
9:00 am-1:32 pm
1 stop6h 32m
Missoula Johnson-Bell Field
Wed 10/28
6:15 am-3:01 pm
1 stop6h 46m
$414
KnoxvilleMissoula
TYS Knoxville McGhee Tyson - MSO Missoula Johnson-Bell Field
TYSMSO
Knoxville McGhee Tyson
Wed 10/21
6:00 am-3:19 pm
2 stops11h 19m
Missoula Johnson-Bell Field
Sun 10/25
2:37 pm-10:32 pm
1 stop5h 55m
$488
KnoxvilleMissoula
TYS Knoxville McGhee Tyson - MSO Missoula Johnson-Bell Field
TYSMSO
Knoxville McGhee Tyson
Fri 10/23
6:00 am-11:32 am
1 stop7h 32m
Missoula Johnson-Bell Field
Fri 10/30
2:37 pm-10:32 pm
1 stop5h 55m
$499
KnoxvilleMissoula
TYS Knoxville McGhee Tyson - MSO Missoula Johnson-Bell Field
TYSMSO
Knoxville McGhee Tyson
Sat 1/30
4:28 pm-9:52 pm
1 stop7h 24m
Missoula Johnson-Bell Field
Tue 2/2
6:10 am-2:55 pm
1 stop6h 45m
$499
Sorted by cheapest first
Compare providers for flights from Knoxville to Missoula
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Knoxville to Missoula in October.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Knoxville-Missoula flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Knoxville-Missoula flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Knoxville-Missoula flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Knoxville-Missoula flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Knoxville-Missoula flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Knoxville to Missoula
Have a flexible travel schedule? Discover the best time to fly to Missoula from Knoxville with our price prediction graph.
TYS-MSO
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Reviews of airlines servicing Missoula
Get insights into the airlines that provide service to Missoula. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missoula. Reviews last updated October 7, 2026.
Read reviews from past customers who have flown United Airlines and American Airlines from Knoxville to Missoula. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Overall
7.4
Comfort
7.3
Entertainment
7.1
Food
6.7
Boarding
7.7
Crew
8.1
Reviews
1 / 20
8.0
ExcellentAsha,Sep 2026
LGA - IAH
Overall
7.4
Comfort
7.3
Entertainment
7.1
Food
6.7
Boarding
7.7
Crew
8.1
Reviews
1 / 20
8.0
ExcellentAsha,Sep 2026
LGA - IAH
Overall
7.4
Comfort
7.3
Entertainment
7.1
Food
6.7
Boarding
7.7
Crew
8.1
Reviews
1 / 20
8.0
ExcellentAsha,Sep 2026
LGA - IAH
Related info for your journey
Find useful and relevant information for your journey from Knoxville to Missoula. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Complete your trip
Complete your trip to Missoula by adding a car rental and/or hotel reservation to your travel itinerary.
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Other flights to Missoula
Explore flights to Missoula departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on October 7, 2026.
Knoxville and Missoula flights
Browse other Knoxville and Missoula flight options. Last updated on October 7, 2026.
Other flights from Knoxville
Browse through other flights departing from Knoxville. Flights are based on user searches made on Cheapflights and were last updated on October 7, 2026.
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Check out other popular destinations found by fellow travelers in 2026
Top 2 airlines flying from Knoxville to Missoula
Discover the top 2 airlines that operate flights from Knoxville to Missoula. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 7, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$288 | Average$534 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$364 | Average$537 | FlexibilityNo cancel fee | On-time69% |