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Missoula

$270+ Cheap flights from Knoxville to Missoula (TYS - MSO)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/8. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — MSO
Jan 5 — Jan 121
Mon 1/5
Mon 1/12
1 adult, Economy
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Cheap flight deals from Knoxville to Missoula

Cheapest flights from Knoxville to Missoula
Explore the most affordable flight options available from Knoxville to Missoula. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 6, 2025.

This United Airlines deal was found by Cheapflights users on 12/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/64:30 pmTYS - MSO
1 stop6h 48mUnited Airlines
Tue 12/96:15 amMSO - TYS
1 stop6h 52mUnited Airlines
Deal found 12/6$519
This American Airlines deal was found by Cheapflights users on 12/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/57:38 amTYS - MSO
2 stops14h 24mAmerican Airlines
Fri 12/127:00 amMSO - TYS
1 stop8h 27mAmerican Airlines
Deal found 12/3$595
This United Airlines deal was found by Cheapflights users on 12/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/149:40 amTYS - MSO
2 stops13h 38mUnited Airlines
Sat 12/205:15 pmMSO - TYS
2 stops15h 41mUnited Airlines
Deal found 12/5$613
This Mytrip deal was found by Cheapflights users on 12/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/57:15 amTYS - MSO
3 stops38h 57mMultiple Airlines
Fri 12/1210:21 amMSO - TYS
3 stops26h 34mMultiple Airlines
Deal found 12/3$838

Find flight deals from Knoxville to Missoula

Discover tips and strategies to find the most affordable flight options for your journey from Knoxville (TYS) to Missoula (MSO). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated December 6, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$354
(American Airlines)

One-way from

$270
(American Airlines)

Popular in

April

Cheapest in

January

Average price

$752
Provider with most accurate pricing for Knoxville McGhee Tyson-Missoula Johnson-Bell Field flight deals.
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Provider most trusted by Cheapflights users for Knoxville McGhee Tyson-Missoula Johnson-Bell Field flights.
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From Knoxville McGhee Tyson to Missoula Johnson-Bell Field
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One-way flight from Knoxville McGhee Tyson to Missoula Johnson-Bell Field
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Highest demand for flights based on searches. 17% potential increase in price ($102 potential increase over avg. RT price).
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Cheapest flight prices on average. 5% potential price decrease ($26 potential savings vs. average RT price).
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Average for round-trip flights in December 2025
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Knoxville to Missoula that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 6, 2025.
Use the filters below to find and compare flights from Knoxville to Missoula that are best for you.

Fly from

Knoxville

Fly to

Missoula

Route

Depart

Return

Price

KnoxvilleMissoula

TYS - MSO

TYSMSO

Knoxville McGhee Tyson

Thu 1/29

7:54 am-12:50 pm

1 stop6h 56m

Missoula Johnson-Bell Field

Sun 2/1

1:21 pm-10:09 pm

1 stop6h 48m

$289

KnoxvilleMissoula

TYS - MSO

TYSMSO

Knoxville McGhee Tyson

Tue 2/3

11:10 am-9:51 pm

2 stops12h 41m

Missoula Johnson-Bell Field

Sat 2/7

6:00 am-8:52 pm

2 stops12h 52m

$389

KnoxvilleMissoula

TYS - MSO

TYSMSO

Knoxville McGhee Tyson

Tue 2/3

2:17 pm-11:55 pm

2 stops11h 38m

Missoula Johnson-Bell Field

Sat 2/7

6:23 am-10:47 pm

2 stops14h 24m

$389

KnoxvilleMissoula

TYS - MSO

TYSMSO

Knoxville McGhee Tyson

Wed 2/11

7:54 am-12:50 pm

1 stop6h 56m

Missoula Johnson-Bell Field

Mon 2/16

1:24 pm-9:23 pm

1 stop5h 59m

$420

KnoxvilleMissoula

TYS - MSO

TYSMSO

Knoxville McGhee Tyson

Wed 2/11

9:30 am-9:51 pm

2 stops14h 21m

Missoula Johnson-Bell Field

Mon 2/16

6:15 am-10:49 am

2 stops26h 34m

$488

KnoxvilleMissoula

TYS - MSO

TYSMSO

Knoxville McGhee Tyson

Sun 3/8

7:40 am-12:51 pm

1 stop7h 11m

$270

KnoxvilleMissoula

TYS - MSO

TYSMSO

Knoxville McGhee Tyson

Sat 3/7

7:40 am-12:54 pm

1 stop7h 14m

$389

KnoxvilleMissoula

TYS - MSO

TYSMSO

Knoxville McGhee Tyson

Sat 3/7

1:30 pm-8:01 pm

2 stops8h 31m

$445

KnoxvilleMissoula

TYS - MSO

TYSMSO

Knoxville McGhee Tyson

Sat 3/7

7:00 am-9:57 pm

2 stops16h 57m

$445

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/5

Compare providers for flights from Knoxville to Missoula

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Knoxville to Missoula in December.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star
eDreamsPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Knoxville-Missoula flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Knoxville-Missoula flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Knoxville-Missoula flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Knoxville-Missoula flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Knoxville-Missoula flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Knoxville to Missoula

Have a flexible travel schedule? Discover the best time to fly to Missoula from Knoxville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Knoxville to Missoula

What is the cheapest month to book a flight from Knoxville to Missoula?

Currently, June is the cheapest month in which you can book a flight from Knoxville to Missoula (average of $279). Flying from Knoxville to Missoula in April is currently the most expensive (average of $603). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Missoula

Get insights into the airlines that provide service to Missoula. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missoula. Reviews last updated December 6, 2025.
Read reviews from past customers who have flown Delta, United Airlines, and American Airlines from Knoxville to Missoula. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,013 reviews

Comfort

7.9

Food

7.3

Overall

7.9

Entertainment

7.9

Boarding

8.1

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,013 reviews
Delta
7.9
Good
8,013 reviews

Comfort

7.9

Food

7.3

Overall

7.9

Entertainment

7.9

Boarding

8.1

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
United Airlines
7.4
Good
9,072 reviews
Delta
7.9
Good
8,013 reviews

Comfort

7.9

Food

7.3

Overall

7.9

Entertainment

7.9

Boarding

8.1

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.2
Good
11,046 reviews
Delta
7.9
Good
8,013 reviews

Comfort

7.9

Food

7.3

Overall

7.9

Entertainment

7.9

Boarding

8.1

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Knoxville to Missoula. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Knoxville to Missoula?

    Airlines like American Airlines, United Airlines, and Alaska Airlines fly from Knoxville to Missoula in about 6h 56m. The time it takes to get you to your destination can typically vary by up to 5h 45m. There are 1724 mi between Knoxville and Missoula. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines flying from Knoxville to Missoula round-trip?

    American Airlines, at $294, was found to be the cheapest airline from Knoxville to Missoula.Alternate airlines to your destination round-trip include Delta and United Airlines. You may be able to fly from Knoxville to Missoula for 40% less than the average price by searching for these airlines.

  • Can I find deals for flights from Knoxville to Missoula that include hotel bookings?

    Yes. In addition to deals on Knoxville to Missoula flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to Missoula?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Missoula.

  • Can I find deals for business class flights from Knoxville to Missoula?

    Yes. Cheapflights offers flight deals from Knoxville to Missoula by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Knoxville to Missoula?

    Currently, June is the cheapest month in which you can book a flight from Knoxville to Missoula (average of $279). Flying from Knoxville to Missoula in April is currently the most expensive (average of $603). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

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Top 3 airlines flying from Knoxville to Missoula

Discover the top 3 airlines that operate flights from Knoxville to Missoula. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 6, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$294Average$383FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$294Average$460FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$354Average$558FlexibilityNo cancel feeOn-time69%

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