Missoula

$300+ Cheap flights from Knoxville to Missoula (TYS - MSO)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/8. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — MSO
Oct 17 — Oct 241
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Cheap flight deals from Knoxville to Missoula

Discover tips and strategies to find the most affordable flight options for your journey from Knoxville (TYS) to Missoula (MSO). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 17, 2025.

Round-trip from

$344
(American Airlines)

One-way from

$300
(American Airlines)

Popular in

April

Cheapest in

March

Average price

$526
From Knoxville McGhee Tyson to Missoula Johnson-Bell Field
One-way flight from Knoxville McGhee Tyson to Missoula Johnson-Bell Field
Highest demand for flights based on searches. 7% potential increase in price ($45 potential increase over avg. RT price).
Cheapest flight prices on average. 4% potential price decrease ($23 potential savings vs. average RT price).
Average for round-trip flights in September 2025

Find flight deals from Knoxville to Missoula

Cheapest flights from Knoxville to Missoula
Explore the most affordable flight options available from Knoxville to Missoula. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 17, 2025.

This United Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/17:00 amTYS - MSO
1 stop6h 50mUnited Airlines
Sun 10/56:25 amMSO - TYS
1 stop6h 41mUnited Airlines
Deal found 9/16$379
This American Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/204:49 pmTYS - MSO
1 stop8h 29mAmerican Airlines
Wed 9/241:51 pmMSO - TYS
1 stop8h 30mAmerican Airlines
Deal found 9/17$454
This United Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/205:45 amTYS - MSO
2 stops12h 55mUnited Airlines
Wed 9/246:30 amMSO - TYS
2 stops12h 26mUnited Airlines
Deal found 9/17$554
This United Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/65:53 pmTYS - MSO
2 stops18h 04mUnited Airlines
Sun 10/125:25 pmMSO - TYS
1 stop27h 03mUnited Airlines
Deal found 9/16$712

Cheapflights Fare Finder

 
Customize your flight search to find flights from Knoxville to Missoula that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 17, 2025.
Use the filters below to find and compare flights from Knoxville to Missoula that are best for you.

Fly from

Knoxville

Fly to

Missoula

Route

Depart

Return

Price

KnoxvilleMissoula

TYS - MSO

TYSMSO

Knoxville McGhee Tyson

Sat 1/10

4:27 pm-9:41 pm

1 stop7h 14m

Missoula Johnson-Bell Field

Sun 1/18

7:00 am-3:23 pm

1 stop6h 23m

$344

KnoxvilleMissoula

TYS - MSO

TYSMSO

Knoxville McGhee Tyson

Sat 1/10

11:30 am-8:17 pm

2 stops10h 47m

Missoula Johnson-Bell Field

Sun 1/18

8:00 am-9:32 pm

2 stops11h 32m

$354

KnoxvilleMissoula

TYS - MSO

TYSMSO

Knoxville McGhee Tyson

Wed 10/1

7:00 am-11:50 am

1 stop6h 50m

Missoula Johnson-Bell Field

Sun 10/5

6:25 am-3:06 pm

1 stop6h 41m

$379

KnoxvilleMissoula

TYS - MSO

TYSMSO

Knoxville McGhee Tyson

Sat 1/10

11:03 am-1:09 pm

3 stops28h 06m

Missoula Johnson-Bell Field

Sun 1/18

5:45 am-9:49 pm

2 stops14h 04m

$558

KnoxvilleMissoula

TYS - MSO

TYSMSO

Knoxville McGhee Tyson

Mon 10/6

5:53 pm-9:57 am

2 stops18h 04m

Missoula Johnson-Bell Field

Sun 10/12

5:25 pm-10:28 pm

1 stop27h 03m

$712

KnoxvilleMissoula

TYS - MSO

TYSMSO

Knoxville McGhee Tyson

Sun 3/8

3:00 pm-9:37 pm

1 stop8h 37m

$300

KnoxvilleMissoula

TYS - MSO

TYSMSO

Knoxville McGhee Tyson

Sat 3/7

4:25 pm-9:26 pm

1 stop7h 01m

$336

KnoxvilleMissoula

TYS - MSO

TYSMSO

Knoxville McGhee Tyson

Sun 3/8

11:07 am-1:52 pm

2 stops28h 45m

$361

KnoxvilleMissoula

TYS - MSO

TYSMSO

Knoxville McGhee Tyson

Sun 3/8

5:39 pm-9:26 pm

3 stops29h 47m

$681

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/16

Best time to book a flight from Knoxville to Missoula

Have a flexible travel schedule? Discover the best time to fly to Missoula from Knoxville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Knoxville to Missoula

What is the cheapest month to book a flight from Knoxville to Missoula?

Currently, October is the cheapest month in which you can book a flight from Knoxville to Missoula (average of $365). Flying from Knoxville to Missoula in March is currently the most expensive (average of $505). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from Knoxville to Missoula?

Reviews of airlines servicing Missoula

Get insights into the airlines that provide service to Missoula. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missoula. Reviews last updated September 17, 2025.
Read reviews from past customers who have flown Delta, United Airlines, and American Airlines from Knoxville to Missoula. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
8.0
Very good

Comfort

7.9

Entertainment

7.9

Food

7.3

Overall

8.0

Crew

8.5

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
8.0
Very good
8.0
Very good

Comfort

7.9

Entertainment

7.9

Food

7.3

Overall

8.0

Crew

8.5

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
8.0
Very good

Comfort

7.9

Entertainment

7.9

Food

7.3

Overall

8.0

Crew

8.5

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
8.0
Very good

Comfort

7.9

Entertainment

7.9

Food

7.3

Overall

8.0

Crew

8.5

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

Find useful and relevant information for your journey from Knoxville to Missoula. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • How long is the flight from Knoxville to Missoula?

    Airlines like American Airlines and Delta fly from Knoxville to Missoula in about 7h 14m. The time it takes to get you to your destination can typically vary by up to 3h 33m. There are 1724 mi between Knoxville and Missoula. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines flying from Knoxville to Missoula round-trip?

    Delta, at $294, was found to be the cheapest airline from Knoxville to Missoula.Alternate airlines to your destination round-trip include American Airlines and United Airlines. You may be able to fly from Knoxville to Missoula for 46% less than the average price by searching for these airlines.

  • What are the cheapest airlines to fly from Knoxville to Missoula one-way?

    The cheapest airlines for a one-way flight from Knoxville to Missoula are American Airlines ($300), United Airlines ($336), and Alaska Airlines ($361).

  • Can I find deals for flights from Knoxville to Missoula that include hotel bookings?

    Yes. In addition to deals on Knoxville to Missoula flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to Missoula?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Missoula.

  • Can I find deals for business class flights from Knoxville to Missoula?

    Yes. Cheapflights offers flight deals from Knoxville to Missoula by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Knoxville to Missoula?

    Currently, October is the cheapest month in which you can book a flight from Knoxville to Missoula (average of $365). Flying from Knoxville to Missoula in March is currently the most expensive (average of $505). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top 3 airlines flying from Knoxville to Missoula

Discover the top 3 airlines that operate flights from Knoxville to Missoula. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 17, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$294Average$383FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$353Average$511FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$354Average$559FlexibilityNo cancel feeOn-time69%

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