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Mississippi

$269+ Cheap flights from South Dakota to Mississippi

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/22. Fares are subject to change and may not be available on all flights or dates of travel.
FSD — JAN
Mar 5 — Mar 121
Thu 3/5
Thu 3/12
1 adult, Economy
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Cheap flight deals from South Dakota to Mississippi

Cheapest flights from South Dakota to Mississippi
Explore the most affordable flight options available from South Dakota to Mississippi. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 3, 2026.

This Delta deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/225:08 am
FSD
-
MEM
1 stop5h 44m
Delta
Mon 3/25:40 pm
MEM
-
FSD
1 stop5h 50m
Delta
Deal found 2/1$269
This American Airlines deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/191:26 pm
FSD
-
MEM
1 stop5h 43m
American Airlines
Sun 2/225:38 am
MEM
-
FSD
1 stop7h 03m
American Airlines
Deal found 2/1$274
This United Airlines deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/171:40 pm
FSD
-
MEM
1 stop6h 59m
United Airlines
Sat 2/219:55 am
MEM
-
FSD
1 stop4h 45m
United Airlines
Deal found 2/2$279
This American Airlines deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/35:21 pm
FSD
-
MEM
1 stop6h 11m
American Airlines
Sun 4/57:01 am
MEM
-
FSD
1 stop4h 37m
American Airlines
Deal found 2/2$280
This American Airlines deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/1712:14 pm
FSD
-
MEM
2 stops10h 39m
American Airlines
Sat 2/215:08 am
MEM
-
FSD
1 stop6h 34m
American Airlines
Deal found 2/2$284
This Delta deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/161:44 pm
FSD
-
MEM
1 stop4h 14m
Delta
Sun 4/196:39 pm
MEM
-
FSD
1 stop4h 23m
Delta
Deal found 2/2$294
This Delta deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/171:44 pm
FSD
-
MEM
1 stop4h 14m
Delta
Mon 4/206:39 pm
MEM
-
FSD
1 stop4h 23m
Delta
Deal found 2/1$304
This Kiwi.com deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/236:14 pm
FSD
-
MEM
2 stops16h 06m
Multiple Airlines
Thu 2/268:09 pm
MEM
-
FSD
1 stop16h 47m
Multiple Airlines
Deal found 2/2$305
This American Airlines deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/222:08 pm
FSD
-
MEM
2 stops9h 43m
American Airlines
Mon 3/24:03 pm
MEM
-
FSD
1 stop5h 37m
American Airlines
Deal found 2/1$314
This American Airlines deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/315:31 pm
FSD
-
MOB
1 stop5h 39m
American Airlines
Tue 4/74:49 pm
MOB
-
FSD
1 stop5h 05m
American Airlines
Deal found 2/3$319
This American Airlines deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/245:15 pm
FSD
-
GPT
1 stop5h 42m
American Airlines
Mon 8/3110:36 am
GPT
-
FSD
1 stop5h 59m
American Airlines
Deal found 2/1$329
This American Airlines deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/11:26 pm
FSD
-
MOB
1 stop5h 26m
American Airlines
Tue 4/75:22 am
MOB
-
FSD
1 stop7h 34m
American Airlines
Deal found 2/3$359

Find flight deals from South Dakota to Mississippi

Keep the following information in mind while searching for South Dakota to Mississippi flight deals. Data was last updated February 3, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$269
(Delta)
Provider with most accurate pricing for Sioux Falls Joe Foss Field-Jackson-Evers Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Sioux Falls Joe Foss Field-Jackson-Evers Intl flights.
Search Deals
From South Dakota to Mississippi
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from South Dakota to Mississippi that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 3, 2026.
Use the filters below to find and compare flights from South Dakota to Mississippi that are best for you.

Fly from

South Dakota

Fly to

Mississippi

Route

Depart

Return

Price

Sioux FallsMemphis

FSD - MEM

FSDMEM

Sioux Falls Joe Foss Field

Sun 2/22

5:08 am-10:52 am

1 stop5h 44m

Memphis

Mon 3/2

5:40 pm-11:30 pm

1 stop5h 50m

$269

Sioux FallsMemphis

FSD - MEM

FSDMEM

Sioux Falls Joe Foss Field

Tue 2/17

1:40 pm-8:39 pm

1 stop6h 59m

Memphis

Sat 2/21

9:55 am-2:40 pm

1 stop4h 45m

$279

Sioux FallsMemphis

FSD - MEM

FSDMEM

Sioux Falls Joe Foss Field

Fri 4/17

7:39 pm-11:59 pm

1 stop4h 20m

Memphis

Mon 4/20

5:36 am-12:56 pm

1 stop7h 20m

$294

Sioux FallsMemphis

FSD - MEM

FSDMEM

Sioux Falls Joe Foss Field

Thu 4/16

1:44 pm-5:58 pm

1 stop4h 14m

Memphis

Sun 4/19

6:39 pm-11:02 pm

1 stop4h 23m

$294

Sioux FallsMemphis

FSD - MEM

FSDMEM

Sioux Falls Joe Foss Field

Thu 2/19

12:14 pm-7:52 pm

2 stops7h 38m

Memphis

Sun 2/22

5:38 am-12:41 pm

1 stop7h 03m

$296

Sioux FallsMemphis

FSD - MEM

FSDMEM

Sioux Falls Joe Foss Field

Fri 4/17

1:44 pm-5:58 pm

1 stop4h 14m

Memphis

Mon 4/20

6:39 pm-11:02 pm

1 stop4h 23m

$304

Sioux FallsMemphis

FSD - MEM

FSDMEM

Sioux Falls Joe Foss Field

Sun 2/22

2:08 pm-11:51 pm

2 stops9h 43m

Memphis

Mon 3/2

4:03 pm-9:40 pm

1 stop5h 37m

$314

Sioux FallsMobile

FSD - MOB

FSDMOB

Sioux Falls Joe Foss Field

Tue 3/31

12:14 pm-10:57 pm

2 stops10h 43m

Mobile

Tue 4/7

4:49 pm-9:54 pm

1 stop5h 05m

$324

Sioux FallsMemphis

FSD - MEM

FSDMEM

Sioux Falls Joe Foss Field

Thu 4/16

1:44 pm-5:58 pm

1 stop4h 14m

Memphis

Mon 4/20

6:39 pm-11:02 pm

1 stop4h 23m

$339

Sioux FallsMobile

FSD - MOB

FSDMOB

Sioux Falls Joe Foss Field

Tue 3/31

5:31 pm-11:10 pm

1 stop5h 39m

Mobile

Sun 4/5

5:22 am-12:41 pm

1 stop7h 19m

$363

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/1

Showing 1-10 of 28 results
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Best time to book a flight from South Dakota to Mississippi

Have a flexible travel schedule? Discover the best time to fly to Mississippi from South Dakota with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Dakota to Mississippi
No data available for this route at this time. Please check back soon.

Reviews of airlines servicing Mississippi

Get insights into the airlines that provide service to Mississippi. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Mississippi. Reviews last updated February 3, 2026.
Read reviews from past customers who have flown American Airlines from South Dakota to Mississippi. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.2
Good
11,212 reviews

Overall

7.2

Crew

8.0

Boarding

7.5

Comfort

7.2

Entertainment

6.9

Food

6.4

Reviews

1 / 20
2.0
Mediocre

Susie,Jan 2026

CLT - TPA

This flight was delayed 3 or 4 times. We had boarded the plane, sat on plane for a good 30 minutes, then we had to board the aircraft, walk to a different gate, wait and then board another aircraft. We arrived in Tampa 4 hours later than the original booking. I feel there should have been some sort of compensation especially for the advantage members.
American Airlines
7.2
Good
11,212 reviews
American Airlines
7.2
Good
11,212 reviews

Overall

7.2

Crew

8.0

Boarding

7.5

Comfort

7.2

Entertainment

6.9

Food

6.4

Reviews

1 / 20
2.0
Mediocre

Susie,Jan 2026

CLT - TPA

This flight was delayed 3 or 4 times. We had boarded the plane, sat on plane for a good 30 minutes, then we had to board the aircraft, walk to a different gate, wait and then board another aircraft. We arrived in Tampa 4 hours later than the original booking. I feel there should have been some sort of compensation especially for the advantage members.

Related info for your journey

Find useful and relevant information for your journey from South Dakota to Mississippi. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from South Dakota to Mississippi?

    Delta, United Airlines, and American Airlines can get you from South Dakota to Mississippi in just under 4h 20m. Your travel time can differ by up to 2h 39m. South Dakota and Mississippi are separated by a distance of 691 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • Can I find deals for flights from South Dakota to Mississippi that include hotel bookings?

    Yes. In addition to deals on South Dakota to Mississippi flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from South Dakota to Mississippi?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Dakota to Mississippi.

  • Can I find deals for business class flights from South Dakota to Mississippi?

    Yes. Cheapflights offers flight deals from South Dakota to Mississippi by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

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Alternative routes for South Dakota to Mississippi

See prices for flight routes from nearby airports that may be better suited for you.
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Top airline flying from South Dakota to Mississippi

Discover the top airline that operate flights from South Dakota to Mississippi. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 3, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$258Average$577FlexibilityNo cancel feeOn-time71%

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