HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Mississippi

$239+ Cheap flights from South Dakota to Mississippi

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/8. Fares are subject to change and may not be available on all flights or dates of travel.
FSD — JAN
Oct 15 — Oct 221
Wed 10/15
Wed 10/22
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from South Dakota to Mississippi with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from South Dakota to Mississippi

Keep the following information in mind while searching for South Dakota to Mississippi flight deals. Data was last updated September 15, 2025.

Round-trip from

$259
(American Airlines)

One-way from

$239
(Delta)
From South Dakota to Mississippi
Search Deals
One-way flight from South Dakota to Mississippi
Search Deals

Find flight deals from South Dakota to Mississippi

Cheapest flights from South Dakota to Mississippi
Explore the most affordable flight options available from South Dakota to Mississippi. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 15, 2025.

This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/191:19 pmFSD - MEM
1 stop4h 47mAmerican Airlines
Sun 9/216:48 amMEM - FSD
1 stop5h 51mAmerican Airlines
Deal found 9/14$324
This American Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/106:35 amFSD - BTR
1 stop7h 10mAmerican Airlines
Sat 12/137:00 amBTR - FSD
1 stop5h 18mAmerican Airlines
Deal found 9/13$329
This American Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/265:33 pmFSD - MOB
1 stop5h 29mAmerican Airlines
Tue 9/305:11 amMOB - FSD
1 stop7h 27mAmerican Airlines
Deal found 9/13$329
This United Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/308:00 amFSD - MEM
2 stops13h 16mUnited Airlines
Sat 10/42:48 pmMEM - FSD
1 stop7h 34mUnited Airlines
Deal found 9/14$334
This Kiwi.com deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/62:23 pmFSD - MEM
2 stops22h 08mMultiple Airlines
Sun 11/98:00 pmMEM - FSD
1 stop17h 47mMultiple Airlines
Deal found 9/13$357
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/61:13 pmFSD - MEM
1 stop5h 18mAmerican Airlines
Sun 11/95:15 amMEM - FSD
1 stop7h 08mAmerican Airlines
Deal found 9/14$377
This United Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/278:00 amFSD - MOB
2 stops10h 44mUnited Airlines
Wed 10/111:30 amMOB - FSD
2 stops10h 52mUnited Airlines
Deal found 9/13$379
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/285:05 pmFSD - MEM
1 stop5h 52mAmerican Airlines
Fri 10/313:42 pmMEM - FSD
1 stop21h 00mAmerican Airlines
Deal found 9/14$382
This American Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/275:33 pmFSD - GPT
1 stop5h 59mAmerican Airlines
Wed 10/15:30 amGPT - FSD
1 stop7h 08mAmerican Airlines
Deal found 9/13$473
This United Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/2011:18 amRAP - JAN
2 stops9h 36mUnited Airlines
Wed 9/2412:04 pmJAN - RAP
2 stops9h 35mUnited Airlines
Deal found 9/14$484
This Delta deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/281:35 pmFSD - MEM
2 stops9h 21mDelta
Fri 10/3112:37 pmMEM - FSD
2 stops6h 42mDelta
Deal found 9/13$487
This American Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/275:33 pmFSD - MOB
1 stop5h 29mAmerican Airlines
Wed 10/15:11 amMOB - FSD
1 stop7h 27mAmerican Airlines
Deal found 9/13$489

Cheapflights Fare Finder

 
Customize your flight search to find flights from South Dakota to Mississippi that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 15, 2025.
Use the filters below to find and compare flights from South Dakota to Mississippi that are best for you.

Fly from

South Dakota

Fly to

Mississippi

Route

Depart

Return

Price

Sioux FallsMobile

FSD - MOB

FSDMOB

Sioux Falls Joe Foss Field

Fri 9/26

5:33 pm-11:02 pm

1 stop5h 29m

Mobile

Tue 9/30

5:11 am-12:38 pm

1 stop7h 27m

$329

Sioux FallsMemphis

FSD - MEM

FSDMEM

Sioux Falls Joe Foss Field

Tue 9/30

3:12 pm-9:48 pm

1 stop6h 36m

Memphis

Sat 10/4

2:48 pm-10:22 pm

1 stop7h 34m

$329

Sioux FallsBaton Rouge

FSD - BTR

FSDBTR

Sioux Falls Joe Foss Field

Wed 12/10

6:35 am-1:45 pm

1 stop7h 10m

Baton Rouge Ryan

Sat 12/13

7:00 am-12:18 pm

1 stop5h 18m

$329

Sioux FallsMobile

FSD - MOB

FSDMOB

Sioux Falls Joe Foss Field

Sat 1/24

4:09 pm-10:59 pm

2 stops6h 50m

Mobile

Sat 1/31

5:55 am-12:35 pm

2 stops6h 40m

$349

Sioux FallsMemphis

FSD - MEM

FSDMEM

Sioux Falls Joe Foss Field

Thu 11/6

2:23 pm-12:31 pm

2 stops22h 08m

Memphis

Sun 11/9

8:00 pm-1:47 pm

1 stop17h 47m

$357

Sioux FallsMemphis

FSD - MEM

FSDMEM

Sioux Falls Joe Foss Field

Thu 11/6

1:13 pm-6:31 pm

1 stop5h 18m

Memphis

Sun 11/9

5:15 am-12:23 pm

1 stop7h 08m

$377

Sioux FallsMobile

FSD - MOB

FSDMOB

Sioux Falls Joe Foss Field

Sat 9/27

8:00 am-6:44 pm

2 stops10h 44m

Mobile

Wed 10/1

11:30 am-10:22 pm

2 stops10h 52m

$379

Sioux FallsMemphis

FSD - MEM

FSDMEM

Sioux Falls Joe Foss Field

Tue 10/28

5:05 pm-10:57 pm

1 stop5h 52m

Memphis

Fri 10/31

3:42 pm-12:42 pm

1 stop21h 00m

$382

Sioux FallsGulfport

FSD - GPT

FSDGPT

Sioux Falls Joe Foss Field

Sat 9/27

5:33 pm-11:32 pm

1 stop5h 59m

Gulfport Biloxi Regional

Wed 10/1

5:30 am-12:38 pm

1 stop7h 08m

$473

Sioux FallsMemphis

FSD - MEM

FSDMEM

Sioux Falls Joe Foss Field

Tue 10/28

1:35 pm-10:56 pm

2 stops9h 21m

Memphis

Fri 10/31

12:37 pm-7:19 pm

2 stops6h 42m

$487

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/14

Showing 1-10 of 18 results
1
2

Best time to book a flight from South Dakota to Mississippi

Have a flexible travel schedule? Discover the best time to fly to Mississippi from South Dakota with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Dakota to Mississippi
No data available for this route at this time. Please check back soon.

Reviews of airlines servicing Mississippi

Get insights into the airlines that provide service to Mississippi. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Mississippi. Reviews last updated September 15, 2025.
Read reviews from past customers who have flown American Airlines from South Dakota to Mississippi. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.2
Good
10,000 reviews

Crew

8.0

Comfort

7.2

Overall

7.2

Entertainment

6.9

Boarding

7.5

Food

6.4

Reviews

1 / 20
2.0
Mediocre

Jeremy,Sep 2025

SAN - PHL

Terrible. Bad customer service and unacceptable delay on the tarmac
American Airlines
7.2
Good
10,000 reviews
American Airlines
7.2
Good
10,000 reviews

Crew

8.0

Comfort

7.2

Overall

7.2

Entertainment

6.9

Boarding

7.5

Food

6.4

Reviews

1 / 20
2.0
Mediocre

Jeremy,Sep 2025

SAN - PHL

Terrible. Bad customer service and unacceptable delay on the tarmac

Related info for your journey

Find useful and relevant information for your journey from South Dakota to Mississippi. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from South Dakota to Mississippi?

    American Airlines, United Airlines, and Delta can get you from South Dakota to Mississippi in just under 5h 29m. Your travel time can differ by up to 1h 21m. South Dakota and Mississippi are separated by a distance of 1004 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • Can I find deals for flights from South Dakota to Mississippi that include hotel bookings?

    Yes. In addition to deals on South Dakota to Mississippi flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from South Dakota to Mississippi?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Dakota to Mississippi.

  • Can I find deals for business class flights from South Dakota to Mississippi?

    Yes. Cheapflights offers flight deals from South Dakota to Mississippi by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from South Dakota to Mississippi?

    Currently, January is the cheapest month in which you can book a flight from South Dakota to Mississippi (average of $371). Flying from South Dakota to Mississippi in March is currently the most expensive (average of $447). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for South Dakota to Mississippi

See prices for flight routes from nearby airports that may be better suited for you.
Los Angeles to John F Kennedy Intl flights
John F Kennedy Intl to Los Angeles flights
John F Kennedy Intl to Las Vegas flights
John F Kennedy Intl to Miami flights
Dallas/Fort Worth to John F Kennedy Intl flights
Dallas/Fort Worth to Las Vegas flights
San Francisco to John F Kennedy Intl flights
Los Angeles to Seattle flights
LaGuardia to Dallas/Fort Worth flights
Dallas/Fort Worth to Seattle flights
Newark to Fort Lauderdale flights
John F Kennedy Intl to O'Hare Intl flights
Los Angeles to Newark flights
O'Hare Intl to John F Kennedy Intl flights
Dallas/Fort Worth to LaGuardia flights
Newark to Las Vegas flights
LaGuardia to O'Hare Intl flights
LaGuardia to Fort Lauderdale flights
Seattle to Las Vegas flights
O'Hare Intl to Las Vegas flights
Newark to O'Hare Intl flights
O'Hare Intl to LaGuardia flights
Newark to Miami flights
San Francisco to Las Vegas flights
John F Kennedy Intl to Atlanta flights
John F Kennedy Intl to Orlando flights
Newark to Dallas/Fort Worth flights
John F Kennedy Intl to Dallas/Fort Worth flights
Dallas/Fort Worth to O'Hare Intl flights
John F Kennedy Intl to San Francisco flights
Seattle to Dallas/Fort Worth flights
Seattle to Los Angeles flights
Newark to Los Angeles flights
Dallas/Fort Worth to Denver flights
LaGuardia to Miami flights
Los Angeles to Honolulu flights
Los Angeles to Dallas/Fort Worth flights
Los Angeles to LaGuardia flights
O'Hare Intl to Dallas/Fort Worth flights
San Francisco to Newark flights
Newark to Orlando flights
O'Hare Intl to Newark flights
Atlanta to John F Kennedy Intl flights
Dallas/Fort Worth to Los Angeles flights
Los Angeles to O'Hare Intl flights
Dallas/Fort Worth to Newark flights
John F Kennedy Intl to Fort Lauderdale flights
John F Kennedy Intl to Sky Harbor Intl flights
Dulles Intl to Dallas/Fort Worth flights
Atlanta to Las Vegas flights

Top airline flying from South Dakota to Mississippi

Discover the top airline that operate flights from South Dakota to Mississippi. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 15, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$258Average$614FlexibilityNo cancel feeOn-time71%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.