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Mississippi

$178+ Cheap flights from South Dakota to Mississippi

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/30. Fares are subject to change and may not be available on all flights or dates of travel.
FSD — JAN
May 4 — May 111
Mon 5/4
Mon 5/11
1 adult, Economy
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Cheap flight deals from South Dakota to Mississippi

Cheapest flights from South Dakota to Mississippi
Explore the most affordable flight options available from South Dakota to Mississippi. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 4, 2026.

This American Airlines deal was found by Cheapflights users on 4/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/61:41 pm
FSD
-
JAN
1 stop5h 51m
American Airlines
Tue 5/122:20 pm
JAN
-
FSD
1 stop7h 34m
American Airlines
Deal found 4/2$329
This American Airlines deal was found by Cheapflights users on 4/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/2212:29 pm
FSD
-
MEM
1 stop6h 35m
American Airlines
Fri 5/15:40 am
MEM
-
FSD
1 stop7h 16m
American Airlines
Deal found 4/2$334
This American Airlines deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/177:39 pm
FSD
-
MEM
1 stop4h 20m
American Airlines
Tue 4/213:44 pm
MEM
-
FSD
1 stop6h 10m
American Airlines
Deal found 4/1$339
This Delta deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/151:44 pm
FSD
-
MEM
1 stop4h 14m
Delta
Sun 4/196:39 pm
MEM
-
FSD
1 stop4h 23m
Delta
Deal found 3/31$369
This American Airlines deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/177:39 pm
FSD
-
MEM
1 stop4h 20m
American Airlines
Sun 5/245:17 pm
MEM
-
FSD
1 stop5h 00m
American Airlines
Deal found 3/31$395
This Kiwi.com deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/152:35 pm
FSD
-
MEM
2 stops26h 41m
Multiple Airlines
Sun 4/196:45 pm
MEM
-
FSD
1 stop22h 36m
Multiple Airlines
Deal found 3/31$401
This United Airlines deal was found by Cheapflights users on 4/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/33:07 pm
FSD
-
MEM
1 stop6h 59m
United Airlines
Mon 7/62:39 pm
MEM
-
FSD
1 stop7h 28m
United Airlines
Deal found 4/2$409
This United Airlines deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/55:00 am
FSD
-
JAN
2 stops11h 12m
United Airlines
Sat 5/912:00 pm
JAN
-
FSD
2 stops11h 29m
United Airlines
Deal found 3/31$419
This United Airlines deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/29:00 am
FSD
-
GPT
2 stops10h 53m
United Airlines
Tue 5/52:00 pm
GPT
-
FSD
2 stops9h 43m
United Airlines
Deal found 3/31$425
This American Airlines deal was found by Cheapflights users on 4/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/135:35 pm
FSD
-
GPT
1 stop5h 26m
American Airlines
Mon 6/1511:23 am
GPT
-
FSD
1 stop5h 32m
American Airlines
Deal found 4/3$427
This United Airlines deal was found by Cheapflights users on 4/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/2810:13 am
RAP
-
JAN
2 stops10h 05m
United Airlines
Tue 9/12:06 pm
JAN
-
RAP
2 stops9h 17m
United Airlines
Deal found 4/4$439
This United Airlines deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/46:10 am
FSD
-
MEM
1 stop4h 44m
United Airlines
Mon 4/66:47 pm
MEM
-
FSD
1 stop4h 57m
United Airlines
Deal found 3/31$449

Find flight deals from South Dakota to Mississippi

Keep the following information in mind while searching for South Dakota to Mississippi flight deals. Data was last updated April 4, 2026.

Round-trip from

$329
(American Airlines)

One-way from

$178
(Kiwi.com)
From South Dakota to Mississippi
Search Deals
One-way flight from South Dakota to Mississippi
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from South Dakota to Mississippi that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 4, 2026.
Use the filters below to find and compare flights from South Dakota to Mississippi that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Sioux FallsJackson

FSD - JAN

FSDJAN

Sioux Falls Joe Foss Field

Wed 5/6

1:41 pm-7:32 pm

1 stop5h 51m

Jackson-Evers Intl

Tue 5/12

2:20 pm-9:54 pm

1 stop7h 34m

$329

Sioux FallsMemphis

FSD - MEM

FSDMEM

Sioux Falls Joe Foss Field

Fri 4/17

7:39 pm-11:59 pm

1 stop4h 20m

Memphis

Tue 4/21

3:44 pm-9:54 pm

1 stop6h 10m

$339
Quickest round-trip

Sioux FallsMemphis

FSD - MEM

FSDMEM

Sioux Falls Joe Foss Field

Wed 4/15

1:44 pm-5:58 pm

1 stop4h 14m

Memphis

Sun 4/19

6:39 pm-11:02 pm

1 stop4h 23m

$369

Sioux FallsMemphis

FSD - MEM

FSDMEM

Sioux Falls Joe Foss Field

Sun 5/17

7:39 pm-11:59 pm

1 stop4h 20m

Memphis

Sun 5/24

5:17 pm-10:17 pm

1 stop5h 00m

$395

Sioux FallsMemphis

FSD - MEM

FSDMEM

Sioux Falls Joe Foss Field

Fri 7/3

3:07 pm-10:06 pm

1 stop6h 59m

Memphis

Mon 7/6

2:39 pm-10:07 pm

1 stop7h 28m

$409

Sioux FallsJackson

FSD - JAN

FSDJAN

Sioux Falls Joe Foss Field

Tue 5/5

5:00 am-4:12 pm

2 stops11h 12m

Jackson-Evers Intl

Sat 5/9

12:00 pm-11:29 pm

2 stops11h 29m

$419

Sioux FallsMemphis

FSD - MEM

FSDMEM

Sioux Falls Joe Foss Field

Wed 4/22

3:17 pm-11:47 pm

2 stops8h 30m

Memphis

Fri 5/1

5:00 am-2:47 pm

2 stops9h 47m

$420

Sioux FallsGulfport

FSD - GPT

FSDGPT

Sioux Falls Joe Foss Field

Sat 5/2

9:00 am-7:53 pm

2 stops10h 53m

Gulfport Biloxi Regional

Tue 5/5

2:00 pm-11:43 pm

2 stops9h 43m

$425

Rapid CityJackson

RAP - JAN

RAPJAN

Rapid City

Fri 8/28

10:13 am-9:18 pm

2 stops10h 05m

Jackson-Evers Intl

Tue 9/1

2:06 pm-10:23 pm

2 stops9h 17m

$439

Sioux FallsMemphis

FSD - MEM

FSDMEM

Sioux Falls Joe Foss Field

Wed 4/15

2:35 pm-3:41 pm

2 stops25h 06m

Memphis

Sun 4/19

7:47 pm-8:03 pm

2 stops24h 16m

$448

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/1

Showing 1-10 of 30 resultsSorted by cheapest first
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Best time to book a flight from South Dakota to Mississippi

Have a flexible travel schedule? Discover the best time to fly to Mississippi from South Dakota with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Dakota to Mississippi
No data available for this route at this time. Please check back soon.

Related info for your journey

Find useful and relevant information for your journey from South Dakota to Mississippi. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from South Dakota to Mississippi?

    American Airlines, Delta, and United Airlines can get you from South Dakota to Mississippi in just under 4h 14m. Your travel time can differ by up to 6h 58m. South Dakota and Mississippi are separated by a distance of 691 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • Can I find deals for flights from South Dakota to Mississippi that include hotel bookings?

    Yes. In addition to deals on South Dakota to Mississippi flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from South Dakota to Mississippi?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Dakota to Mississippi.

  • Can I find deals for business class flights from South Dakota to Mississippi?

    Yes. Cheapflights offers flight deals from South Dakota to Mississippi by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

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Alternative routes for South Dakota to Mississippi

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