HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Mississippi

$239+ Cheap flights from Sioux Falls (FSD) to Mississippi

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/3. Fares are subject to change and may not be available on all flights or dates of travel.
FSD — JAN
Jan 11 — Jan 181
Sun 1/11
Sun 1/18
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Sioux Falls to Mississippi with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Sioux Falls to Mississippi

Cheapest flights from Sioux Falls to Mississippi
Explore the most affordable flight options available from Sioux Falls to Mississippi. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 12, 2025.

This American Airlines deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/251:16 pmFSD - MEM
1 stop5h 57mAmerican Airlines
Mon 12/295:28 pmMEM - FSD
1 stop6h 31mAmerican Airlines
Deal found 12/10$309
This American Airlines deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/177:00 amFSD - BTR
2 stops10h 00mAmerican Airlines
Sun 1/114:38 pmBTR - FSD
1 stop5h 26mAmerican Airlines
Deal found 12/10$389
This United Airlines deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/263:08 pmFSD - MEM
1 stop6h 50mUnited Airlines
Tue 12/307:30 amMEM - FSD
1 stop6h 57mUnited Airlines
Deal found 12/11$398
This American Airlines deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/3110:41 amFSD - MEM
1 stop6h 17mAmerican Airlines
Sat 1/35:44 pmMEM - FSD
1 stop6h 15mAmerican Airlines
Deal found 12/11$407
This American Airlines deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/216:00 amFSD - BTR
1 stop7h 48mAmerican Airlines
Tue 12/304:21 pmBTR - FSD
1 stop4h 56mAmerican Airlines
Deal found 12/10$414
This American Airlines deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/205:16 pmFSD - JAN
1 stop5h 57mAmerican Airlines
Tue 12/234:22 pmJAN - FSD
1 stop4h 55mAmerican Airlines
Deal found 12/11$461
This American Airlines deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/111:09 pmFSD - BTR
1 stop6h 15mAmerican Airlines
Sun 12/215:32 amBTR - FSD
1 stop6h 56mAmerican Airlines
Deal found 12/10$469
This American Airlines deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/201:10 pmFSD - JAN
1 stop6h 10mAmerican Airlines
Mon 12/224:22 pmJAN - FSD
1 stop4h 55mAmerican Airlines
Deal found 12/10$490
This United Airlines deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/1111:20 amFSD - BTR
2 stops8h 08mUnited Airlines
Sun 12/211:48 pmBTR - FSD
2 stops10h 07mUnited Airlines
Deal found 12/10$499
This American Airlines deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/267:29 pmFSD - MEM
1 stop4h 45mAmerican Airlines
Tue 12/309:27 amMEM - FSD
2 stops9h 32mAmerican Airlines
Deal found 12/11$521
This United Airlines deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/218:50 amFSD - BTR
2 stops8h 42mUnited Airlines
Tue 12/305:10 amBTR - FSD
2 stops16h 46mUnited Airlines
Deal found 12/10$624
This American Airlines deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/191:16 pmFSD - JAN
1 stop6h 04mAmerican Airlines
Tue 12/234:22 pmJAN - FSD
1 stop4h 55mAmerican Airlines
Deal found 12/10$631

Find flight deals from Sioux Falls to Mississippi

Keep the following information in mind while searching for Sioux Falls to Mississippi flight deals. Data was last updated December 12, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$249
(American Airlines)

One-way from

$239
(American Airlines)
Provider with most accurate pricing for Sioux Falls Joe Foss Field-Jackson-Evers Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Sioux Falls Joe Foss Field-Jackson-Evers Intl flights.
Search Deals
From Sioux Falls Joe Foss Field to Mississippi
Search Deals
One-way flight from Sioux Falls Joe Foss Field to Mississippi
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Sioux Falls to Mississippi that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 12, 2025.
Use the filters below to find and compare flights from Sioux Falls to Mississippi that are best for you.

Fly from

Sioux Falls

Fly to

Mississippi

Route

Depart

Return

Price

Sioux FallsMemphis

FSD - MEM

FSDMEM

Sioux Falls Joe Foss Field

Thu 1/29

5:35 pm-10:51 pm

1 stop5h 16m

Memphis

Sun 2/1

6:40 am-11:51 am

1 stop5h 11m

$249

Sioux FallsMemphis

FSD - MEM

FSDMEM

Sioux Falls Joe Foss Field

Thu 2/12

5:00 am-11:41 am

1 stop6h 41m

Memphis

Tue 2/17

6:00 am-12:15 pm

1 stop6h 15m

$279

Sioux FallsMemphis

FSD - MEM

FSDMEM

Sioux Falls Joe Foss Field

Sat 1/17

7:30 am-2:45 pm

1 stop7h 15m

Memphis

Sun 1/18

4:15 pm-11:44 pm

1 stop7h 29m

$289

Sioux FallsMemphis

FSD - MEM

FSDMEM

Sioux Falls Joe Foss Field

Thu 2/19

7:52 pm-11:59 pm

1 stop4h 07m

Memphis

Sun 2/22

5:38 am-12:27 pm

1 stop6h 49m

$294

Sioux FallsMemphis

FSD - MEM

FSDMEM

Sioux Falls Joe Foss Field

Thu 12/25

1:16 pm-7:13 pm

1 stop5h 57m

Memphis

Mon 12/29

5:28 pm-11:59 pm

1 stop6h 31m

$309

Sioux FallsMemphis

FSD - MEM

FSDMEM

Sioux Falls Joe Foss Field

Thu 1/1

7:29 pm-11:59 pm

1 stop4h 30m

Memphis

Sun 1/4

5:28 pm-12:01 am

1 stop6h 33m

$334

Sioux FallsMemphis

FSD - MEM

FSDMEM

Sioux Falls Joe Foss Field

Thu 1/1

7:29 pm-11:59 pm

1 stop4h 30m

Memphis

Sat 1/3

5:44 pm-11:59 pm

1 stop6h 15m

$334

Sioux FallsGulfport

FSD - GPT

FSDGPT

Sioux Falls Joe Foss Field

Tue 2/10

1:07 pm-9:53 pm

2 stops8h 46m

Gulfport Biloxi Regional

Thu 2/19

6:00 pm-11:30 pm

1 stop5h 30m

$344

Sioux FallsMobile

FSD - MOB

FSDMOB

Sioux Falls Joe Foss Field

Sat 1/10

5:35 pm-10:59 pm

1 stop5h 24m

Mobile

Tue 1/13

10:44 am-4:59 pm

1 stop6h 15m

$344

Sioux FallsMemphis

FSD - MEM

FSDMEM

Sioux Falls Joe Foss Field

Thu 2/12

7:52 pm-11:59 pm

1 stop4h 07m

Memphis

Tue 2/17

11:34 am-10:34 pm

2 stops11h 00m

$347

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/9

Showing 1-10 of 41 results
1
2
3
...
5

Best time to book a flight from Sioux Falls to Mississippi

Have a flexible travel schedule? Discover the best time to fly to Mississippi from Sioux Falls with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Sioux Falls to Mississippi
No data available for this route at this time. Please check back soon.

Reviews of airlines servicing Mississippi

Get insights into the airlines that provide service to Mississippi. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Mississippi. Reviews last updated December 12, 2025.
Read through reviews of airlines operating flights from Sioux Falls to Mississippi, such as American Airlines. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.2
Good
11,050 reviews

Entertainment

6.9

Crew

8.0

Boarding

7.5

Overall

7.2

Food

6.5

Comfort

7.2

Reviews

1 / 20
10.0
Excellent

Jeremy,Dec 2025

OKC - CLT

Was an okay flight. Had extra seat empty beside me so was able to stretch a bit
American Airlines
7.2
Good
11,050 reviews
American Airlines
7.2
Good
11,050 reviews

Entertainment

6.9

Crew

8.0

Boarding

7.5

Overall

7.2

Food

6.5

Comfort

7.2

Reviews

1 / 20
10.0
Excellent

Jeremy,Dec 2025

OKC - CLT

Was an okay flight. Had extra seat empty beside me so was able to stretch a bit

Related info for your journey

Find useful and relevant information for your journey from Sioux Falls to Mississippi. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Sioux Falls to Mississippi?

    Located just 2.6 mi from the city center, Sioux Falls Joe Foss Field (FSD) is the airport most travelers will use when flying to Mississippi from Sioux Falls.

  • How long is the flight from Sioux Falls to Mississippi?

    Departing from Sioux Falls to Mississippi will take you 5h 16m. Airlines will cover a distance of 691 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the most popular routes from Sioux Falls to Mississippi?

    While some choose either Sioux Falls Joe Foss Field - Mobile or Sioux Falls Joe Foss Field - Gulfport Biloxi Regional, Sioux Falls Joe Foss Field - Jackson-Evers Intl is the most popular route from Sioux Falls to Mississippi.

  • Can I find deals for flights from Sioux Falls to Mississippi that include hotel bookings?

    Yes. In addition to deals on Sioux Falls to Mississippi flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Sioux Falls to Mississippi?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Sioux Falls to Mississippi.

  • Can I find deals for business class flights from Sioux Falls to Mississippi?

    Yes. Cheapflights offers flight deals from Sioux Falls to Mississippi by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Sioux Falls to Mississippi

See prices for flight routes from nearby airports that may be better suited for you.
Sioux Falls to Dallas/Fort Worth flights
Sioux Falls to Sky Harbor Intl flights
Sioux Falls to Denver flights
Sioux Falls to O'Hare Intl flights
Sioux Falls to Orlando flights
Sioux Falls to Las Vegas flights
Rapid City to Orlando flights
Sioux Falls to Phoenix-Mesa Gateway flights
Sioux Falls to Tampa flights
Sioux Falls to Los Angeles flights
Sioux Falls to LaGuardia flights
Sioux Falls to Hobby flights
Sioux Falls to Midway flights
Sioux Falls to Pensacola flights
Sioux Falls to Palm Springs flights
Sioux Falls to Newark flights
Sioux Falls to Savannah flights
Sioux Falls to San Diego flights
Sioux Falls to John F Kennedy Intl flights
Sioux Falls to Sarasota flights
Rapid City to Fort Lauderdale flights
Rapid City to O'Hare Intl flights
Sioux Falls to Fort Lauderdale flights
Rapid City to Madison flights
Sioux Falls to Ontario flights
Sioux Falls to Fort Myers flights
Sioux Falls to Portland flights
Sioux Falls to Miami flights
Sioux Falls to George Bush Intcntl flights
Sioux Falls to Minneapolis flights
Sioux Falls to Salt Lake City flights
Sioux Falls to Spokane flights
Rapid City to Las Vegas flights
Sioux Falls to Reagan-National flights
Rapid City to San Diego flights
Sioux Falls to Indianapolis flights
Sioux Falls to Dulles Intl flights
Sioux Falls to Atlanta flights
Rapid City to Dallas/Fort Worth flights
Sioux Falls to Honolulu flights
Sioux Falls to Key West flights
Sioux Falls to Oklahoma City flights
Rapid City to Cincinnati flights
Sioux Falls to Seattle flights
Rapid City to Miami flights
Sioux Falls to Nashville flights
Rapid City to Los Angeles flights
Sioux Falls to San Francisco flights
Rapid City to Tampa flights
Rapid City to Sky Harbor Intl flights

Top airline flying from Sioux Falls to Mississippi

Discover the top airline that operate flights from Sioux Falls to Mississippi. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 12, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$258Average$614FlexibilityNo cancel feeOn-time71%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.