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Mississippi

$269+ Cheap flights from Sioux Falls (FSD) to Mississippi

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/19. Fares are subject to change and may not be available on all flights or dates of travel.
FSD — JAN
Feb 27 — Mar 61
Fri 2/27
Fri 3/6
1 adult, Economy
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Cheap flight deals from Sioux Falls to Mississippi

Cheapest flights from Sioux Falls to Mississippi
Explore the most affordable flight options available from Sioux Falls to Mississippi. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 28, 2026.

This American Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/191:26 pm
FSD
-
MEM
1 stop5h 43m
American Airlines
Sun 2/227:00 am
MEM
-
FSD
1 stop5h 41m
American Airlines
Deal found 1/27$269
This American Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/315:31 pm
FSD
-
MOB
1 stop5h 39m
American Airlines
Tue 4/75:22 am
MOB
-
FSD
1 stop7h 39m
American Airlines
Deal found 1/27$279
This American Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/115:38 pm
FSD
-
MEM
1 stop5h 13m
American Airlines
Sun 2/154:03 pm
MEM
-
FSD
1 stop4h 57m
American Airlines
Deal found 1/27$279
This Delta deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/45:00 am
FSD
-
MEM
1 stop6h 43m
Delta
Wed 2/115:22 pm
MEM
-
FSD
1 stop5h 48m
Delta
Deal found 1/27$309
This American Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/11:26 pm
FSD
-
MOB
1 stop5h 26m
American Airlines
Tue 4/75:22 am
MOB
-
FSD
1 stop7h 39m
American Airlines
Deal found 1/27$319
This American Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/46:00 am
FSD
-
MEM
2 stops9h 08m
American Airlines
Wed 2/118:37 am
MEM
-
FSD
2 stops12h 43m
American Airlines
Deal found 1/27$319
This Delta deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/41:20 pm
FSD
-
MOB
2 stops9h 35m
Delta
Fri 8/144:15 pm
MOB
-
FSD
1 stop5h 54m
Delta
Deal found 1/27$339
This Delta deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/1111:02 am
FSD
-
MEM
2 stops10h 15m
Delta
Sun 2/1512:25 pm
MEM
-
FSD
1 stop7h 16m
Delta
Deal found 1/27$345
This American Airlines deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/65:35 pm
FSD
-
MOB
1 stop5h 24m
American Airlines
Mon 2/93:20 pm
MOB
-
FSD
1 stop6h 44m
American Airlines
Deal found 1/26$354
This American Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/175:31 pm
FSD
-
BTR
1 stop5h 08m
American Airlines
Sat 2/215:00 am
BTR
-
FSD
1 stop7h 42m
American Airlines
Deal found 1/27$369
This American Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/15:28 pm
FSD
-
MOB
1 stop5h 31m
American Airlines
Wed 5/64:49 pm
MOB
-
FSD
1 stop5h 14m
American Airlines
Deal found 1/27$399
This American Airlines deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/75:35 pm
FSD
-
BTR
1 stop5h 21m
American Airlines
Wed 2/1110:33 am
BTR
-
FSD
1 stop6h 20m
American Airlines
Deal found 1/26$409

Find flight deals from Sioux Falls to Mississippi

Keep the following information in mind while searching for Sioux Falls to Mississippi flight deals. Data was last updated January 28, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$269
(American Airlines)
Provider with most accurate pricing for Sioux Falls Joe Foss Field-Jackson-Evers Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Sioux Falls Joe Foss Field-Jackson-Evers Intl flights.
Search Deals
From Sioux Falls Joe Foss Field to Mississippi
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Sioux Falls to Mississippi that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 28, 2026.
Use the filters below to find and compare flights from Sioux Falls to Mississippi that are best for you.

Fly from

Sioux Falls

Fly to

Mississippi

Route

Depart

Return

Price

Sioux FallsMemphis

FSD - MEM

FSDMEM

Sioux Falls Joe Foss Field

Thu 2/19

1:26 pm-7:09 pm

1 stop5h 43m

Memphis

Sun 2/22

7:00 am-12:41 pm

1 stop5h 41m

$269

Sioux FallsMobile

FSD - MOB

FSDMOB

Sioux Falls Joe Foss Field

Tue 3/31

5:31 pm-11:10 pm

1 stop5h 39m

Mobile

Tue 4/7

5:22 am-1:01 pm

1 stop7h 39m

$279

Sioux FallsMemphis

FSD - MEM

FSDMEM

Sioux Falls Joe Foss Field

Wed 2/11

5:38 pm-10:51 pm

1 stop5h 13m

Memphis

Sun 2/15

4:03 pm-9:00 pm

1 stop4h 57m

$279

Sioux FallsMobile

FSD - MOB

FSDMOB

Sioux Falls Joe Foss Field

Wed 4/1

1:26 pm-6:52 pm

1 stop5h 26m

Mobile

Tue 4/7

5:22 am-1:01 pm

1 stop7h 39m

$319

Sioux FallsMemphis

FSD - MEM

FSDMEM

Sioux Falls Joe Foss Field

Wed 2/11

11:02 am-9:17 pm

2 stops10h 15m

Memphis

Sun 2/15

12:25 pm-7:41 pm

1 stop7h 16m

$345

Sioux FallsBaton Rouge

FSD - BTR

FSDBTR

Sioux Falls Joe Foss Field

Tue 2/17

5:31 pm-10:39 pm

1 stop5h 08m

Baton Rouge Ryan

Sat 2/21

5:00 am-12:42 pm

1 stop7h 42m

$369

Sioux FallsMobile

FSD - MOB

FSDMOB

Sioux Falls Joe Foss Field

Fri 5/1

5:28 pm-10:59 pm

1 stop5h 31m

Mobile

Wed 5/6

4:49 pm-10:03 pm

1 stop5h 14m

$399

Sioux FallsBaton Rouge

FSD - BTR

FSDBTR

Sioux Falls Joe Foss Field

Sat 2/7

1:02 pm-10:01 pm

2 stops8h 59m

Baton Rouge Ryan

Wed 2/11

5:00 pm-11:10 pm

1 stop6h 10m

$414

Sioux FallsJackson

FSD - JAN

FSDJAN

Sioux Falls Joe Foss Field

Tue 3/10

12:14 pm-10:56 pm

2 stops10h 42m

Jackson-Evers Intl

Sat 3/14

9:15 am-4:51 pm

1 stop7h 36m

$417

Sioux FallsMemphis

FSD - MEM

FSDMEM

Sioux Falls Joe Foss Field

Tue 2/17

1:40 pm-8:39 pm

1 stop6h 59m

Memphis

Sat 2/21

6:35 pm-9:57 pm

1 stop27h 22m

$419

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/26

Showing 1-10 of 31 results
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Best time to book a flight from Sioux Falls to Mississippi

Have a flexible travel schedule? Discover the best time to fly to Mississippi from Sioux Falls with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Sioux Falls to Mississippi
No data available for this route at this time. Please check back soon.

Reviews of airlines servicing Mississippi

Get insights into the airlines that provide service to Mississippi. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Mississippi. Reviews last updated January 28, 2026.
Read through reviews of airlines operating flights from Sioux Falls to Mississippi, such as American Airlines. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.2
Good
11,201 reviews

Food

6.4

Boarding

7.5

Comfort

7.2

Entertainment

6.9

Crew

8.0

Overall

7.2

Reviews

1 / 20
2.0
Mediocre

Susie,Jan 2026

CLT - TPA

This flight was delayed 3 or 4 times. We had boarded the plane, sat on plane for a good 30 minutes, then we had to board the aircraft, walk to a different gate, wait and then board another aircraft. We arrived in Tampa 4 hours later than the original booking. I feel there should have been some sort of compensation especially for the advantage members.
American Airlines
7.2
Good
11,201 reviews
American Airlines
7.2
Good
11,201 reviews

Food

6.4

Boarding

7.5

Comfort

7.2

Entertainment

6.9

Crew

8.0

Overall

7.2

Reviews

1 / 20
2.0
Mediocre

Susie,Jan 2026

CLT - TPA

This flight was delayed 3 or 4 times. We had boarded the plane, sat on plane for a good 30 minutes, then we had to board the aircraft, walk to a different gate, wait and then board another aircraft. We arrived in Tampa 4 hours later than the original booking. I feel there should have been some sort of compensation especially for the advantage members.

Related info for your journey

Find useful and relevant information for your journey from Sioux Falls to Mississippi. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Sioux Falls to Mississippi?

    Located just 2.6 mi from the city center, Sioux Falls Joe Foss Field (FSD) is the airport most travelers will use when flying to Mississippi from Sioux Falls.

  • How long is the flight from Sioux Falls to Mississippi?

    Departing from Sioux Falls to Mississippi will take you 5h 43m. Airlines will cover a distance of 691 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the most popular routes from Sioux Falls to Mississippi?

    While some choose either Sioux Falls Joe Foss Field - Baton Rouge Ryan or Sioux Falls Joe Foss Field - Memphis, Sioux Falls Joe Foss Field - Mobile is the most popular route from Sioux Falls to Mississippi.

  • Can I find deals for flights from Sioux Falls to Mississippi that include hotel bookings?

    Yes. In addition to deals on Sioux Falls to Mississippi flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Sioux Falls to Mississippi?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Sioux Falls to Mississippi.

  • Can I find deals for business class flights from Sioux Falls to Mississippi?

    Yes. Cheapflights offers flight deals from Sioux Falls to Mississippi by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

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Alternative routes for Sioux Falls to Mississippi

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Top airline flying from Sioux Falls to Mississippi

Discover the top airline that operate flights from Sioux Falls to Mississippi. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 28, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$258Average$577FlexibilityNo cancel feeOn-time71%

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