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$180+ Cheap flights from Sioux Falls (FSD) to Mississippi

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/10. Fares are subject to change and may not be available on all flights or dates of travel.
FSD — JAN
Sep 2 — Sep 91
Tue 9/2
Tue 9/9
1 adult, Economy
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Cheap flight deals from Sioux Falls to Mississippi

Keep the following information in mind while searching for Sioux Falls to Mississippi flight deals. Data was last updated August 28, 2025.

Round-trip from

$168
(Frontier)
From Sioux Falls Joe Foss Field to Mississippi
Search Deals

Find flight deals from Sioux Falls to Mississippi

Cheapest flights from Sioux Falls to Mississippi
Explore the most affordable flight options available from Sioux Falls to Mississippi. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 28, 2025.

This Delta deal was found by Cheapflights users on 8/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/105:00 amFSD - MEM
1 stop6h 37mDelta
Sun 9/146:00 amMEM - FSD
1 stop4h 07mDelta
Deal found 8/26$259
This Frontier deal was found by Cheapflights users on 8/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/72:54 pmFSD - MEM
1 stop23h 57mFrontier
Sun 9/148:04 pmMEM - FSD
1 stop18h 05mFrontier
Deal found 8/28$269
This American Airlines deal was found by Cheapflights users on 8/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/166:27 pmFSD - MEM
1 stop5h 32mAmerican Airlines
Sun 10/195:23 amMEM - FSD
1 stop7h 24mAmerican Airlines
Deal found 8/26$279
This American Airlines deal was found by Cheapflights users on 8/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/135:33 pmFSD - MOB
1 stop5h 29mAmerican Airlines
Sun 9/145:14 amMOB - FSD
1 stop7h 25mAmerican Airlines
Deal found 8/27$289
This American Airlines deal was found by Cheapflights users on 8/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/195:33 pmFSD - MEM
1 stop5h 24mAmerican Airlines
Mon 9/295:25 amMEM - FSD
1 stop7h 13mAmerican Airlines
Deal found 8/26$294
This Delta deal was found by Cheapflights users on 8/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/165:30 amFSD - MEM
2 stops11h 31mDelta
Mon 10/206:36 pmMEM - FSD
1 stop4h 21mDelta
Deal found 8/26$313
This American Airlines deal was found by Cheapflights users on 8/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/265:33 pmFSD - MOB
1 stop5h 29mAmerican Airlines
Tue 9/305:11 amMOB - FSD
1 stop7h 27mAmerican Airlines
Deal found 8/26$314
This American Airlines deal was found by Cheapflights users on 8/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/305:15 pmFSD - MEM
1 stop5h 38mAmerican Airlines
Mon 9/110:33 amMEM - FSD
1 stop7h 00mAmerican Airlines
Deal found 8/26$338
This American Airlines deal was found by Cheapflights users on 8/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/285:15 pmFSD - MOB
1 stop5h 42mAmerican Airlines
Tue 9/26:25 amMOB - FSD
2 stops14h 38mAmerican Airlines
Deal found 8/26$384
This American Airlines deal was found by Cheapflights users on 8/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/1012:19 pmFSD - MEM
2 stops9h 10mAmerican Airlines
Sun 9/147:10 amMEM - FSD
2 stops9h 38mAmerican Airlines
Deal found 8/26$392
This American Airlines deal was found by Cheapflights users on 8/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/185:05 pmFSD - MOB
1 stop6h 13mAmerican Airlines
Sun 10/263:32 pmMOB - FSD
1 stop5h 43mAmerican Airlines
Deal found 8/27$394
This United Airlines deal was found by Cheapflights users on 8/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/1311:20 amFSD - MOB
2 stops8h 21mUnited Airlines
Sun 9/149:18 amMOB - FSD
2 stops12h 54mUnited Airlines
Deal found 8/27$398

Cheapflights Fare Finder

 
Customize your flight search to find flights from Sioux Falls to Mississippi that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 28, 2025.
Use the filters below to find and compare flights from Sioux Falls to Mississippi that are best for you.

Fly from

Sioux Falls

Fly to

Mississippi

Route

Depart

Return

Price

Sioux FallsMemphis

FSD - MEM

FSDMEM

Sioux Falls Joe Foss Field

Wed 9/10

5:00 am-11:37 am

1 stop6h 37m

Memphis

Sun 9/14

6:00 am-10:07 am

1 stop4h 07m

$259

Sioux FallsMemphis

FSD - MEM

FSDMEM

Sioux Falls Joe Foss Field

Sun 9/7

2:54 pm-2:51 pm

1 stop23h 57m

Memphis

Sun 9/14

8:04 pm-2:09 pm

1 stop18h 05m

$269

Sioux FallsMemphis

FSD - MEM

FSDMEM

Sioux Falls Joe Foss Field

Thu 10/16

6:27 pm-11:59 pm

1 stop5h 32m

Memphis

Sun 10/19

5:23 am-12:47 pm

1 stop7h 24m

$279

Sioux FallsMobile

FSD - MOB

FSDMOB

Sioux Falls Joe Foss Field

Sat 9/13

5:33 pm-11:02 pm

1 stop5h 29m

Mobile

Sun 9/14

5:14 am-12:39 pm

1 stop7h 25m

$289

Sioux FallsMemphis

FSD - MEM

FSDMEM

Sioux Falls Joe Foss Field

Fri 9/19

5:33 pm-10:57 pm

1 stop5h 24m

Memphis

Mon 9/29

5:25 am-12:38 pm

1 stop7h 13m

$294

Sioux FallsMemphis

FSD - MEM

FSDMEM

Sioux Falls Joe Foss Field

Thu 10/16

6:27 pm-11:59 pm

1 stop5h 32m

Memphis

Mon 10/20

5:27 pm-10:42 pm

1 stop5h 15m

$294

Sioux FallsMemphis

FSD - MEM

FSDMEM

Sioux Falls Joe Foss Field

Thu 10/16

5:30 am-5:01 pm

2 stops11h 31m

Memphis

Mon 10/20

6:36 pm-10:57 pm

1 stop4h 21m

$313

Sioux FallsMobile

FSD - MOB

FSDMOB

Sioux Falls Joe Foss Field

Fri 9/26

5:33 pm-11:02 pm

1 stop5h 29m

Mobile

Tue 9/30

5:11 am-12:38 pm

1 stop7h 27m

$314

Sioux FallsMobile

FSD - MOB

FSDMOB

Sioux Falls Joe Foss Field

Wed 10/15

5:05 pm-11:18 pm

1 stop6h 13m

Mobile

Sat 10/18

5:12 am-12:42 pm

1 stop7h 30m

$314

Sioux FallsMemphis

FSD - MEM

FSDMEM

Sioux Falls Joe Foss Field

Wed 9/10

12:19 pm-9:29 pm

2 stops9h 10m

Memphis

Sun 9/14

7:10 am-4:48 pm

2 stops9h 38m

$392

Flights are sorted by cheapest round-trip flights first.

Deals found on 8/27

Showing 1-10 of 26 results
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Best time to book a flight from Sioux Falls to Mississippi

Have a flexible travel schedule? Discover the best time to fly to Mississippi from Sioux Falls with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Sioux Falls to Mississippi
No data available for this route at this time. Please check back soon.

Reviews of airlines servicing Mississippi

Get insights into the airlines that provide service to Mississippi. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Mississippi. Reviews last updated August 28, 2025.
Read through reviews of airlines operating flights from Sioux Falls to Mississippi, such as American Airlines. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.2
Good
10,000 reviews

Overall

7.2

Entertainment

6.9

Food

6.5

Comfort

7.2

Boarding

7.5

Crew

8.0

Reviews

1 / 20
2.0
Mediocre

Anonymous,Aug 2025

BNA - ORD

My flight was 8 hours delayed, so I missed my connecting flight to Dublin. I understand it’s not the staff’s fault but the lack of sympathy and apology was appalling. I had been sat in the airport since 4am until 3pm and they did not seem understanding. Not good. Need better customer service.
American Airlines
7.2
Good
10,000 reviews
American Airlines
7.2
Good
10,000 reviews

Overall

7.2

Entertainment

6.9

Food

6.5

Comfort

7.2

Boarding

7.5

Crew

8.0

Reviews

1 / 20
2.0
Mediocre

Anonymous,Aug 2025

BNA - ORD

My flight was 8 hours delayed, so I missed my connecting flight to Dublin. I understand it’s not the staff’s fault but the lack of sympathy and apology was appalling. I had been sat in the airport since 4am until 3pm and they did not seem understanding. Not good. Need better customer service.

Related info for your journey

Find useful and relevant information for your journey from Sioux Falls to Mississippi. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Sioux Falls to Mississippi?

    Located just 2.6 mi from the city center, Sioux Falls Joe Foss Field (FSD) is the airport most travelers will use when flying to Mississippi from Sioux Falls.

  • How long is the flight from Sioux Falls to Mississippi?

    Departing from Sioux Falls to Mississippi will take you 5h 32m. Airlines will cover a distance of 691 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines to fly from Sioux Falls to Mississippi one-way?

    The cheapest airline one-way is United Airlines, with whom users have recently found tickets for as low as $180. However, be on the lookout for offers from Delta and American Airlines, as they are both options that can get you from Sioux Falls to Mississippi for a low price.

  • What are the most popular routes from Sioux Falls to Mississippi?

    While some choose either Sioux Falls Joe Foss Field - Memphis or Sioux Falls Joe Foss Field - Gulfport Biloxi Regional, Sioux Falls Joe Foss Field - Mobile is the most popular route from Sioux Falls to Mississippi.

  • Can I find deals for flights from Sioux Falls to Mississippi that include hotel bookings?

    Yes. In addition to deals on Sioux Falls to Mississippi flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Sioux Falls to Mississippi?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Sioux Falls to Mississippi.

  • Can I find deals for business class flights from Sioux Falls to Mississippi?

    Yes. Cheapflights offers flight deals from Sioux Falls to Mississippi by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Sioux Falls to Mississippi?

    Currently, January is the cheapest month in which you can book a flight from Sioux Falls to Mississippi (average of $371). Flying from Sioux Falls to Mississippi in March is currently the most expensive (average of $448). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

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Top airline flying from Sioux Falls to Mississippi

Discover the top airline that operate flights from Sioux Falls to Mississippi. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 28, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$258Average$614FlexibilityNo cancel feeOn-time71%

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