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$295+ Cheap flights from Panama to Mississippi

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/28. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — JAN
Oct 15 — Oct 221
Wed 10/15
Wed 10/22
1 adult, Economy
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Cheap flight deals from Panama to Mississippi

Keep the following information in mind while searching for Panama to Mississippi flight deals. Data was last updated September 15, 2025.

Round-trip from

$524
(United Airlines)

One-way from

$295
(United Airlines)
From Panama to Mississippi
Search Deals
One-way flight from Panama to Mississippi
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Find flight deals from Panama to Mississippi

Cheapest flights from Panama to Mississippi
Explore the most affordable flight options available from Panama to Mississippi. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 15, 2025.

This United Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/153:30 pmPTY - JAN
1 stop21h 59mUnited Airlines
Wed 10/225:05 pmJAN - PTY
1 stop21h 09mUnited Airlines
Deal found 9/15$524
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/153:15 pmPTY - JAN
2 stops24h 48mAmerican Airlines
Wed 10/223:32 pmJAN - PTY
2 stops22h 31mAmerican Airlines
Deal found 9/15$549
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/13:15 pmPTY - JAN
2 stops22h 16mAmerican Airlines
Wed 11/59:15 amJAN - PTY
2 stops27h 34mAmerican Airlines
Deal found 9/14$571
This United Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/274:41 pmPTY - BTR
1 stop23h 40mUnited Airlines
Sun 11/305:07 amBTR - PTY
1 stop13h 31mUnited Airlines
Deal found 9/14$571
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/32:49 pmPTY - BTR
2 stops23h 56mAmerican Airlines
Mon 11/103:08 pmBTR - PTY
2 stops21h 41mAmerican Airlines
Deal found 9/14$598
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/163:15 pmPTY - BTR
2 stops22h 33mAmerican Airlines
Mon 10/206:36 pmBTR - PTY
2 stops19h 27mAmerican Airlines
Deal found 9/14$606
This Mytrip deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/2610:05 pmPTY - MEM
3 stops25h 45mMultiple Airlines
Fri 10/37:55 pmMEM - PTY
3 stops28h 15mMultiple Airlines
Deal found 9/14$636
This United Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/17:55 amPTY - JAN
1 stop30h 27mUnited Airlines
Wed 11/512:00 pmJAN - PTY
1 stop25h 45mUnited Airlines
Deal found 9/14$642
This United Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/38:55 amPTY - BTR
1 stop14h 49mUnited Airlines
Mon 11/106:09 pmBTR - PTY
1 stop24h 29mUnited Airlines
Deal found 9/14$645
This United Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/2510:00 amPTY - MEM
1 stop11h 47mUnited Airlines
Fri 10/38:40 amMEM - PTY
1 stop9h 57mUnited Airlines
Deal found 9/15$654
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/272:43 pmPTY - BTR
2 stops26h 46mAmerican Airlines
Sun 11/304:25 pmBTR - PTY
2 stops20h 18mAmerican Airlines
Deal found 9/14$678
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/253:31 pmPTY - MEM
2 stops25h 17mAmerican Airlines
Fri 10/35:45 pmMEM - PTY
2 stops20h 46mAmerican Airlines
Deal found 9/15$683

Cheapflights Fare Finder

 
Customize your flight search to find flights from Panama to Mississippi that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 15, 2025.
Use the filters below to find and compare flights from Panama to Mississippi that are best for you.

Fly from

Panama

Fly to

Mississippi

Route

Depart

Return

Price

Panama CityJackson

PTY - JAN

PTYJAN

Panama City Tocumen Intl

Wed 10/15

3:30 pm-1:29 pm

1 stop21h 59m

Jackson-Evers Intl

Wed 10/22

5:05 pm-2:14 pm

1 stop21h 09m

$524

Panama CityMemphis

PTY - MEM

PTYMEM

Panama City Tocumen Intl

Mon 3/9

2:20 pm-10:52 pm

1 stop8h 32m

Memphis

Wed 3/11

7:20 pm-12:55 pm

1 stop17h 35m

$524

Panama CityJackson

PTY - JAN

PTYJAN

Panama City Tocumen Intl

Wed 10/15

3:15 pm-4:03 pm

2 stops24h 48m

Jackson-Evers Intl

Wed 10/22

3:32 pm-2:03 pm

2 stops22h 31m

$549

Panama CityJackson

PTY - JAN

PTYJAN

Panama City Tocumen Intl

Sat 11/1

3:15 pm-1:31 pm

2 stops22h 16m

Jackson-Evers Intl

Wed 11/5

9:15 am-1:49 pm

2 stops27h 34m

$571

Panama CityBaton Rouge

PTY - BTR

PTYBTR

Panama City Tocumen Intl

Thu 11/27

4:41 pm-3:21 pm

1 stop23h 40m

Baton Rouge Ryan

Sun 11/30

5:07 am-7:38 pm

1 stop13h 31m

$571

Panama CityBaton Rouge

PTY - BTR

PTYBTR

Panama City Tocumen Intl

Mon 11/3

2:49 pm-1:45 pm

2 stops23h 56m

Baton Rouge Ryan

Mon 11/10

3:08 pm-1:49 pm

2 stops21h 41m

$598

Panama CityBaton Rouge

PTY - BTR

PTYBTR

Panama City Tocumen Intl

Thu 10/16

3:15 pm-1:48 pm

2 stops22h 33m

Baton Rouge Ryan

Mon 10/20

6:36 pm-2:03 pm

2 stops19h 27m

$606

Panama CityMemphis

PTY - MEM

PTYMEM

Panama City Tocumen Intl

Fri 9/26

10:05 pm-11:50 pm

3 stops25h 45m

Memphis

Fri 10/3

7:55 pm-12:10 am

3 stops28h 15m

$636

Panama CityMemphis

PTY - MEM

PTYMEM

Panama City Tocumen Intl

Thu 9/25

10:05 pm-11:50 pm

3 stops25h 45m

Memphis

Fri 10/3

7:55 pm-12:10 am

3 stops28h 15m

$637

Panama CityJackson

PTY - JAN

PTYJAN

Panama City Tocumen Intl

Sat 11/1

7:55 am-2:22 pm

1 stop30h 27m

Jackson-Evers Intl

Wed 11/5

12:00 pm-2:45 pm

1 stop25h 45m

$642

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/15

Showing 1-10 of 19 results
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Best time to book a flight from Panama to Mississippi

Have a flexible travel schedule? Discover the best time to fly to Mississippi from Panama with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Panama to Mississippi
No data available for this route at this time. Please check back soon.

Related info for your journey

Find useful and relevant information for your journey from Panama to Mississippi. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Panama to Mississippi?

    United Airlines, Delta, and American Airlines can get you from Panama to Mississippi in just under 8h 32m. Your travel time can differ by up to 16h 16m. The distance from Panama to Mississippi is about 1914 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • Can I find deals for flights from Panama to Mississippi that include hotel bookings?

    Yes. In addition to deals on Panama to Mississippi flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Panama to Mississippi?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama to Mississippi.

  • Can I find deals for business class flights from Panama to Mississippi?

    Yes. Cheapflights offers flight deals from Panama to Mississippi by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Panama to Mississippi?

    Currently, January is the cheapest month in which you can book a flight from Panama to Mississippi (average of $371). Flying from Panama to Mississippi in March is currently the most expensive (average of $447). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Panama to Mississippi

See prices for flight routes from nearby airports that may be better suited for you.
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