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$316+ Cheap flights from La Crosse (LSE) to Mississippi

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/6. Fares are subject to change and may not be available on all flights or dates of travel.
LSE — JAN
Jan 3 — Jan 101
Sat 1/3
Sat 1/10
1 adult, Economy
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Cheap flight deals from La Crosse to Mississippi

Cheapest flights from La Crosse to Mississippi
Explore the most affordable flight options available from La Crosse to Mississippi. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 4, 2025.

This American Airlines deal was found by Cheapflights users on 12/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/1910:09 amLSE - MEM
1 stop5h 05mAmerican Airlines
Tue 12/237:05 amMEM - LSE
2 stops12h 31mAmerican Airlines
Deal found 12/4$671

Find flight deals from La Crosse to Mississippi

Keep the following information in mind while searching for La Crosse to Mississippi flight deals. Data was last updated December 4, 2025.

Round-trip from

$561
(American Airlines)

One-way from

$398
(American Airlines)
From La Crosse to Mississippi
Search Deals
One-way flight from La Crosse to Mississippi
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from La Crosse to Mississippi that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 4, 2025.
Use the filters below to find and compare flights from La Crosse to Mississippi that are best for you.

Fly from

La Crosse

Fly to

Mississippi

Route

Depart

Return

Price

La CrosseJackson

LSE - JAN

LSEJAN

La Crosse

Sat 1/24

6:00 am-3:14 pm

2 stops9h 14m

Jackson-Evers Intl

Tue 1/27

6:47 am-4:16 pm

2 stops9h 29m

$561

La CrosseMemphis

LSE - MEM

LSEMEM

La Crosse

Fri 12/19

10:09 am-3:14 pm

1 stop5h 05m

Memphis

Tue 12/23

7:05 am-7:36 pm

2 stops12h 31m

$671

La CrosseMemphis

LSE - MEM

LSEMEM

La Crosse

Fri 3/6

11:43 am-6:13 pm

3 stops54h 30m

$316

La CrosseMemphis

LSE - MEM

LSEMEM

La Crosse

Fri 3/6

6:21 pm-11:59 pm

1 stop5h 38m

$432

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/4

Best time to book a flight from La Crosse to Mississippi

Have a flexible travel schedule? Discover the best time to fly to Mississippi from La Crosse with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from La Crosse to Mississippi
No data available for this route at this time. Please check back soon.

Related info for your journey

Find useful and relevant information for your journey from La Crosse to Mississippi. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from La Crosse to Mississippi?

    For a flight from La Crosse to Mississippi, you will be flying from La Crosse. La Crosse (LSE) is just 5.4 mi from the center of the city.

  • How long is the flight from La Crosse to Mississippi?

    There are many flights that can get you from La Crosse to Mississippi in 9h 14m. Fly via American Airlines to get the fastest option. The distance between La Crosse and Mississippi is about 802 mi.

  • What are the most popular routes from La Crosse to Mississippi?

    Most travelers choose La Crosse - Laurel Hattiesburg-PineBelt, La Crosse - Baton Rouge Ryan or La Crosse - Gulfport Biloxi Regional when deciding on the best route from La Crosse to Mississippi.

  • Can I find deals for flights from La Crosse to Mississippi that include hotel bookings?

    Yes. In addition to deals on La Crosse to Mississippi flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from La Crosse to Mississippi?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from La Crosse to Mississippi.

  • Can I find deals for business class flights from La Crosse to Mississippi?

    Yes. Cheapflights offers flight deals from La Crosse to Mississippi by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

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Alternative routes for La Crosse to Mississippi

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