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$480+ Cheap flights from La Crosse (LSE) to Mississippi

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/31. Fares are subject to change and may not be available on all flights or dates of travel.
LSE — JAN
Nov 19 — Nov 261
Wed 11/19
Wed 11/26
1 adult, Economy
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Cheap flight deals from La Crosse to Mississippi

Keep the following information in mind while searching for La Crosse to Mississippi flight deals. Data was last updated October 20, 2025.

Round-trip from

$480
(American Airlines)
From La Crosse to Mississippi
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Find flight deals from La Crosse to Mississippi

Cheapest flights from La Crosse to Mississippi
Explore the most affordable flight options available from La Crosse to Mississippi. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 20, 2025.

This American Airlines deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/289:50 amLSE - GPT
2 stops14h 07mAmerican Airlines
Mon 12/14:54 pmGPT - LSE
2 stops16h 26mAmerican Airlines
Deal found 10/19$872

Cheapflights Fare Finder

 
Customize your flight search to find flights from La Crosse to Mississippi that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 20, 2025.
Use the filters below to find and compare flights from La Crosse to Mississippi that are best for you.

Fly from

La Crosse

Fly to

Mississippi

Route

Depart

Return

Price

La CrosseMemphis

LSE - MEM

LSEMEM

La Crosse

Tue 3/31

4:46 pm-8:25 pm

1 stop3h 39m

Memphis

Sat 4/4

7:14 am-2:18 pm

1 stop7h 04m

$480

La CrosseGulfport

LSE - GPT

LSEGPT

La Crosse

Fri 11/28

9:50 am-11:57 pm

2 stops14h 07m

Gulfport Biloxi Regional

Mon 12/1

4:54 pm-9:20 am

2 stops16h 26m

$872

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/17

Best time to book a flight from La Crosse to Mississippi

Have a flexible travel schedule? Discover the best time to fly to Mississippi from La Crosse with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from La Crosse to Mississippi
No data available for this route at this time. Please check back soon.

Related info for your journey

Find useful and relevant information for your journey from La Crosse to Mississippi. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from La Crosse to Mississippi?

    For a flight from La Crosse to Mississippi, you will be flying from La Crosse. La Crosse (LSE) is just 5.4 mi from the center of the city.

  • How long is the flight from La Crosse to Mississippi?

    There are many flights that can get you from La Crosse to Mississippi in 3h 39m. Fly via American Airlines to get the fastest option. The distance between La Crosse and Mississippi is about 614 mi.

  • What are the most popular routes from La Crosse to Mississippi?

    Most travelers choose La Crosse - Laurel Hattiesburg-PineBelt, La Crosse - Gulfport Biloxi Regional or La Crosse - Baton Rouge Ryan when deciding on the best route from La Crosse to Mississippi.

  • Can I find deals for flights from La Crosse to Mississippi that include hotel bookings?

    Yes. In addition to deals on La Crosse to Mississippi flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from La Crosse to Mississippi?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from La Crosse to Mississippi.

  • Can I find deals for business class flights from La Crosse to Mississippi?

    Yes. Cheapflights offers flight deals from La Crosse to Mississippi by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

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