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$83+ Cheap flights from Key Largo, FL to Mississippi

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/8. Fares are subject to change and may not be available on all flights or dates of travel.
MIA — JAN
oct. 11 — oct. 181
sáb. 10/11
sáb. 10/18
1 adult, Economy
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Cheap flight deals from Key Largo to Mississippi

Keep the following information in mind while searching for Key Largo to Mississippi flight deals. Data was last updated septiembre 11, 2025.

Round-trip from

$159
(American Airlines)

One-way from

$83
(Southwest)

Popular in

August

Cheapest in

October

Average price

$598
From Key Largo to Mississippi
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One-way flight from Key Largo to Mississippi
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Highest demand for flights based on searches. 17% potential increase in price ($103 potential increase over avg. RT price).
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Cheapest flight prices on average. 5% potential price decrease ($24 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Find flight deals from Key Largo to Mississippi

Cheapest flights from Key Largo to Mississippi
Explore the most affordable flight options available from Key Largo to Mississippi. Find the lowest fares from popular airlines and budget airlines, with prices last updated on septiembre 11, 2025.

This American Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 10/1510:30 pmMIA - MEM
Nonstop2h 29mAmerican Airlines
sáb. 10/186:15 pmMEM - MIA
Nonstop2h 24mAmerican Airlines
Deal found 9/9$159
This Southwest deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 10/87:55 amMIA - MEM
1 stop7h 40mSouthwest
mié. 10/152:45 pmMEM - MIA
1 stop4h 50mSouthwest
Deal found 9/8$166
This American Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 10/710:30 pmMIA - MEM
Nonstop2h 29mAmerican Airlines
mar. 10/146:00 amMEM - MIA
Nonstop2h 20mAmerican Airlines
Deal found 9/9$169
This American Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 10/810:30 pmMIA - MEM
Nonstop2h 29mAmerican Airlines
mié. 10/156:00 amMEM - MIA
Nonstop2h 20mAmerican Airlines
Deal found 9/8$173
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 10/49:46 pmMIA - MEM
Nonstop2h 37mAmerican Airlines
mar. 10/76:00 amMEM - MIA
Nonstop2h 20mAmerican Airlines
Deal found 9/10$179
This Southwest deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 10/49:15 amMIA - MEM
1 stop6h 55mSouthwest
mar. 10/76:30 amMEM - MIA
1 stop4h 45mSouthwest
Deal found 9/10$184
This American Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 10/1610:30 pmMIA - MEM
Nonstop2h 29mAmerican Airlines
sáb. 10/186:15 pmMEM - MIA
Nonstop2h 24mAmerican Airlines
Deal found 9/11$191
This Delta deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 10/1512:09 pmMIA - MEM
1 stop5h 52mDelta
sáb. 10/184:40 pmMEM - MIA
1 stop6h 49mDelta
Deal found 9/9$197
This Delta deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 10/77:10 amMIA - MEM
1 stop5h 22mDelta
mar. 10/142:35 pmMEM - MIA
1 stop5h 16mDelta
Deal found 9/9$198
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 9/307:50 pmMIA - MEM
Nonstop2h 39mAmerican Airlines
mié. 10/15:54 amMEM - MIA
Nonstop2h 26mAmerican Airlines
Deal found 9/10$199
This Delta deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 10/46:00 amMIA - JAN
1 stop6h 38mDelta
sáb. 10/111:01 pmJAN - MIA
1 stop6h 50mDelta
Deal found 9/10$237
This United Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 10/178:45 amMIA - JAN
1 stop8h 19mUnited Airlines
sáb. 10/182:05 pmJAN - MIA
1 stop7h 47mUnited Airlines
Deal found 9/9$243

Cheapflights Fare Finder

 
Customize your flight search to find flights from Key Largo to Mississippi that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated septiembre 11, 2025.
Use the filters below to find and compare flights from Key Largo to Mississippi that are best for you.

Fly from

Key Largo

Fly to

Mississippi

Route

Depart

Return

Price

MiamiMemphis

MIA - MEM

MIAMEM

Miami

mié. 10/8

7:55 am-2:35 pm

1 stop7h 40m

Memphis

mié. 10/15

2:45 pm-8:35 pm

1 stop4h 50m

$166

MiamiMemphis

MIA - MEM

MIAMEM

Miami

sáb. 10/4

9:46 pm-11:23 pm

Nonstop2h 37m

Memphis

mar. 10/7

6:00 am-9:20 am

Nonstop2h 20m

$183

MiamiMemphis

MIA - MEM

MIAMEM

Miami

sáb. 11/1

6:50 am-3:55 pm

1 stop10h 05m

Memphis

mié. 11/5

3:30 pm-8:25 pm

1 stop3h 55m

$184

MiamiMemphis

MIA - MEM

MIAMEM

Miami

sáb. 10/4

9:15 am-3:10 pm

1 stop6h 55m

Memphis

mar. 10/7

6:30 am-12:15 pm

1 stop4h 45m

$184

MiamiMemphis

MIA - MEM

MIAMEM

Miami

mar. 10/7

7:10 am-11:32 am

1 stop5h 22m

Memphis

mar. 10/14

2:35 pm-8:51 pm

1 stop5h 16m

$198

MiamiMemphis

MIA - MEM

MIAMEM

Miami

sáb. 10/4

7:25 pm-11:03 pm

1 stop4h 38m

Memphis

mar. 10/7

4:40 pm-12:29 am

1 stop6h 49m

$199

MiamiMemphis

MIA - MEM

MIAMEM

Miami

mar. 10/14

7:55 am-2:35 pm

1 stop7h 40m

Memphis

vie. 10/17

11:35 am-11:15 pm

1 stop10h 40m

$213

MiamiMemphis

MIA - MEM

MIAMEM

Miami

jue. 10/16

5:16 pm-11:59 pm

1 stop7h 43m

Memphis

sáb. 10/18

6:15 pm-9:39 pm

Nonstop2h 24m

$214

MiamiMemphis

MIA - MEM

MIAMEM

Miami

jue. 10/16

8:11 am-1:30 pm

1 stop6h 19m

Memphis

sáb. 10/18

4:40 pm-12:29 am

1 stop6h 49m

$220

MiamiJackson

MIA - JAN

MIAJAN

Miami

sáb. 10/4

6:00 am-9:18 am

1 stop4h 18m

Jackson-Evers Intl

sáb. 10/11

5:58 pm-12:29 am

1 stop5h 31m

$237

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/9

Showing 1-10 of 60 results
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Best time to book a flight from Key Largo to Mississippi

Have a flexible travel schedule? Discover the best time to fly to Mississippi from Key Largo with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Key Largo to Mississippi

What is the cheapest month to book a flight from Key Largo to Mississippi?

Currently, January is the cheapest month in which you can book a flight from Key Largo to Mississippi (average of $371). Flying from Key Largo to Mississippi in March is currently the most expensive (average of $448). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from KE9 to MS?

Find hourly flight availability from Key Largo to Mississippi. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated septiembre 11, 2025.

When flying from Key Largo to Mississippi, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Reviews of airlines servicing Mississippi

Get insights into the airlines that provide service to Mississippi. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Mississippi. Reviews last updated septiembre 11, 2025.
Read through reviews of airlines operating flights from Key Largo to Mississippi, such as Delta and American Airlines. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,960 reviews

Entertainment

7.9

Food

7.3

Overall

8.0

Comfort

7.9

Crew

8.5

Boarding

8.2

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.
Delta
8.0
Very good
7,960 reviews
Delta
8.0
Very good
7,960 reviews

Entertainment

7.9

Food

7.3

Overall

8.0

Comfort

7.9

Crew

8.5

Boarding

8.2

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,960 reviews

Entertainment

7.9

Food

7.3

Overall

8.0

Comfort

7.9

Crew

8.5

Boarding

8.2

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.

Related info for your journey

Find useful and relevant information for your journey from Key Largo to Mississippi. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Key Largo to Mississippi?

    There are many flights that can get you from Key Largo to Mississippi in 2h 37m. Fly via Southwest, American Airlines, or Delta to get the fastest option. The distance between Key Largo and Mississippi is about 860 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines to fly from Key Largo to Mississippi one-way?

    The cheapest airline one-way is Southwest, with whom users have recently found tickets for as low as $83. However, be on the lookout for offers from Frontier and United Airlines, as they are both options that can get you from Key Largo to Mississippi for a low price.

  • What are the most popular routes from Key Largo to Mississippi?

    The most popular flight routes from Key Largo to Mississippi are Miami - Memphis, Miami - Baton Rouge Ryan and Miami - Gulfport Biloxi Regional.

  • Can I find deals for flights from Key Largo to Mississippi that include hotel bookings?

    Yes. In addition to deals on Key Largo to Mississippi flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Key Largo to Mississippi?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Key Largo to Mississippi.

  • Can I find deals for business class flights from Key Largo to Mississippi?

    Yes. Cheapflights offers flight deals from Key Largo to Mississippi by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Key Largo to Mississippi?

    Currently, January is the cheapest month in which you can book a flight from Key Largo to Mississippi (average of $371). Flying from Key Largo to Mississippi in March is currently the most expensive (average of $448). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Key Largo to Mississippi

See prices for flight routes from nearby airports that may be better suited for you.
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Top 2 airlines flying from Key Largo to Mississippi

Discover the top 2 airlines that operate flights from Key Largo to Mississippi. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated septiembre 11, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$169Average$379FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$219Average$380FlexibilityNo cancel feeOn-time71%

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