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$114+ Cheap flights from Buffalo (BUF) to Mississippi

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/12. Fares are subject to change and may not be available on all flights or dates of travel.
BUF — JAN
Jan 13 — Jan 201
Tue 1/13
Tue 1/20
1 adult, Economy
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Cheap flight deals from Buffalo to Mississippi

Cheapest flights from Buffalo to Mississippi
Explore the most affordable flight options available from Buffalo to Mississippi. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 14, 2025.

This American Airlines deal was found by Cheapflights users on 12/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/277:15 pmBUF - MEM
1 stop5h 41mAmerican Airlines
Wed 12/317:05 amMEM - BUF
2 stops8h 19mAmerican Airlines
Deal found 12/12$373
This Kiwi.com deal was found by Cheapflights users on 12/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/153:18 pmBUF - MEM
1 stop28h 29mMultiple Airlines
Sat 12/208:17 pmMEM - BUF
1 stop15h 19mMultiple Airlines
Deal found 12/12$443
This American Airlines deal was found by Cheapflights users on 12/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/1612:57 pmBUF - GPT
1 stop5h 05mAmerican Airlines
Sat 12/274:48 pmGPT - BUF
1 stop6h 24mAmerican Airlines
Deal found 12/13$458
This Delta deal was found by Cheapflights users on 12/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/315:52 pmBUF - MOB
2 stops17h 36mDelta
Fri 1/25:59 pmMOB - BUF
1 stop4h 48mDelta
Deal found 12/12$458
This Delta deal was found by Cheapflights users on 12/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/306:00 amBUF - BTR
1 stop4h 49mDelta
Wed 12/313:46 pmBTR - BUF
1 stop6h 51mDelta
Deal found 12/13$468
This Delta deal was found by Cheapflights users on 12/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/315:52 pmBUF - MOB
2 stops17h 36mDelta
Sat 1/36:02 pmMOB - BUF
1 stop4h 45mDelta
Deal found 12/12$488
This American Airlines deal was found by Cheapflights users on 12/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/287:00 amBUF - MEM
1 stop5h 20mAmerican Airlines
Thu 1/13:49 pmMEM - BUF
1 stop6h 08mAmerican Airlines
Deal found 12/13$489
This Delta deal was found by Cheapflights users on 12/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/306:00 amBUF - BTR
1 stop4h 49mDelta
Thu 1/110:34 amBTR - BUF
2 stops10h 59mDelta
Deal found 12/13$502
This American Airlines deal was found by Cheapflights users on 12/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/277:15 pmBUF - MOB
1 stop5h 41mAmerican Airlines
Wed 12/3110:53 amMOB - BUF
1 stop6h 38mAmerican Airlines
Deal found 12/12$524
This Kiwi.com deal was found by Cheapflights users on 12/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/286:32 pmBUF - MEM
1 stop17h 58mMultiple Airlines
Thu 1/18:17 pmMEM - BUF
2 stops44h 53mMultiple Airlines
Deal found 12/13$541
This American Airlines deal was found by Cheapflights users on 12/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/287:00 amBUF - MEM
1 stop5h 20mAmerican Airlines
Sat 1/36:58 pmMEM - BUF
1 stop4h 14mAmerican Airlines
Deal found 12/13$558
This Kiwi.com deal was found by Cheapflights users on 12/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/133:18 pmBUF - MEM
1 stop28h 29mMultiple Airlines
Sat 12/208:17 pmMEM - BUF
1 stop15h 19mMultiple Airlines
Deal found 12/12$568

Find flight deals from Buffalo to Mississippi

Keep the following information in mind while searching for Buffalo to Mississippi flight deals. Data was last updated December 14, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$279
(Delta)

One-way from

$114
(Kiwi.com)
Provider with most accurate pricing for Buffalo-Jackson-Evers Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Buffalo-Jackson-Evers Intl flights.
Search Deals
From Buffalo to Mississippi
Search Deals
One-way flight from Buffalo to Mississippi
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Buffalo to Mississippi that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 14, 2025.
Use the filters below to find and compare flights from Buffalo to Mississippi that are best for you.

Fly from

Buffalo

Fly to

Mississippi

Route

Depart

Return

Price

BuffaloMobile

BUF - MOB

BUFMOB

Buffalo

Fri 1/30

6:49 pm-10:43 pm

1 stop4h 54m

Mobile

Sun 2/8

6:00 am-1:14 pm

1 stop6h 14m

$279

BuffaloMobile

BUF - MOB

BUFMOB

Buffalo

Thu 1/29

6:49 pm-10:43 pm

1 stop4h 54m

Mobile

Sun 2/8

6:00 am-1:14 pm

1 stop6h 14m

$279

BuffaloGulfport

BUF - GPT

BUFGPT

Buffalo

Thu 5/7

4:57 pm-10:07 pm

1 stop6h 10m

Gulfport Biloxi Regional

Sat 5/23

10:30 am-3:59 pm

1 stop4h 29m

$299

BuffaloMemphis

BUF - MEM

BUFMEM

Buffalo

Thu 2/5

6:03 am-9:52 am

1 stop4h 49m

Memphis

Sat 2/14

6:00 am-1:03 pm

1 stop6h 03m

$328

BuffaloMobile

BUF - MOB

BUFMOB

Buffalo

Thu 1/29

5:12 am-4:59 pm

2 stops12h 47m

Mobile

Sun 2/8

6:13 am-12:08 pm

1 stop4h 55m

$330

BuffaloMemphis

BUF - MEM

BUFMEM

Buffalo

Thu 2/5

5:30 am-2:00 pm

2 stops9h 30m

Memphis

Sat 2/14

10:40 am-5:50 pm

1 stop6h 10m

$334

BuffaloMemphis

BUF - MEM

BUFMEM

Buffalo

Thu 1/22

5:12 am-10:18 am

1 stop6h 06m

Memphis

Mon 1/26

5:48 pm-11:42 pm

1 stop4h 54m

$341

BuffaloMemphis

BUF - MEM

BUFMEM

Buffalo

Thu 1/22

5:44 pm-9:17 pm

1 stop4h 33m

Memphis

Mon 1/26

6:00 am-11:19 am

1 stop4h 19m

$341

BuffaloMobile

BUF - MOB

BUFMOB

Buffalo

Sat 1/31

2:49 pm-7:51 pm

1 stop6h 02m

Mobile

Wed 2/4

12:45 pm-7:25 pm

1 stop5h 40m

$349

BuffaloBaton Rouge

BUF - BTR

BUFBTR

Buffalo

Fri 1/30

6:53 am-1:59 pm

1 stop8h 06m

Baton Rouge Ryan

Sun 2/1

5:31 pm-11:41 pm

1 stop5h 10m

$357

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/13

Showing 1-10 of 35 results
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Best time to book a flight from Buffalo to Mississippi

Have a flexible travel schedule? Discover the best time to fly to Mississippi from Buffalo with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Buffalo to Mississippi

What is the cheapest month to book a flight from Buffalo to Mississippi?

Currently, June is the cheapest month in which you can book a flight from Buffalo to Mississippi (average of $178). Flying from Buffalo to Mississippi in July is currently the most expensive (average of $392). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from BUF to MS?

Find hourly flight availability from Buffalo to Mississippi. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 14, 2025.

A simple way to save on the total cost of your ticket is to fly from Buffalo to Mississippi in the evening. If you’re flexible enough to do this you can expect to save up to 15% on your trip compared to booking a flight at noon.

Reviews of airlines servicing Mississippi

Get insights into the airlines that provide service to Mississippi. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Mississippi. Reviews last updated December 14, 2025.
Peruse reviews from past customers who have flown with Delta and American Airlines from Buffalo to Mississippi to help guide your decision. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,007 reviews

Overall

7.9

Entertainment

7.9

Food

7.3

Boarding

8.1

Comfort

7.9

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.
Delta
7.9
Good
8,007 reviews
Delta
7.9
Good
8,007 reviews

Overall

7.9

Entertainment

7.9

Food

7.3

Boarding

8.1

Comfort

7.9

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.
American Airlines
7.2
Good
11,052 reviews
Delta
7.9
Good
8,007 reviews

Overall

7.9

Entertainment

7.9

Food

7.3

Boarding

8.1

Comfort

7.9

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.

Related info for your journey

Find useful and relevant information for your journey from Buffalo to Mississippi. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Buffalo to Mississippi?

    If you book a flight to Mississippi from Buffalo, you will be flying from Buffalo, which is the city’s only airport. Buffalo (BUF) is located 8.3 mi from the center of Buffalo.

  • How long is the flight from Buffalo to Mississippi?

    A quick flight from Buffalo to Mississippi can take about 4h 54m. Delta provides one of the quickest options available for as low as $279. There are 994 mi between Buffalo and Mississippi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the most popular routes from Buffalo to Mississippi?

    The most popular flight routes from Buffalo to Mississippi are Buffalo - Memphis, Buffalo - Mobile and Buffalo - Gulfport Biloxi Regional.

  • Can I find deals for flights from Buffalo to Mississippi that include hotel bookings?

    Yes. In addition to deals on Buffalo to Mississippi flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Buffalo to Mississippi?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Buffalo to Mississippi.

  • Can I find deals for business class flights from Buffalo to Mississippi?

    Yes. Cheapflights offers flight deals from Buffalo to Mississippi by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Buffalo to Mississippi?

    Currently, June is the cheapest month in which you can book a flight from Buffalo to Mississippi (average of $178). Flying from Buffalo to Mississippi in July is currently the most expensive (average of $392). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top 2 airlines flying from Buffalo to Mississippi

Discover the top 2 airlines that operate flights from Buffalo to Mississippi. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 14, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$258Average$592FlexibilityNo cancel feeOn-time71%
DeltaCheapest$278Average$418FlexibilityNo cancel feeOn-timeN/A

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