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$110+ Cheap flights from Buffalo (BUF) to Mississippi

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/25. Fares are subject to change and may not be available on all flights or dates of travel.
BUF — JAN
Oct 11 — Oct 181
Sat 10/11
Sat 10/18
1 adult, Economy
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Cheap flight deals from Buffalo to Mississippi

Keep the following information in mind while searching for Buffalo to Mississippi flight deals. Data was last updated September 11, 2025.

Round-trip from

$231
(United Airlines)

One-way from

$110
(American Airlines)
From Buffalo to Mississippi
Search Deals
One-way flight from Buffalo to Mississippi
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Find flight deals from Buffalo to Mississippi

Cheapest flights from Buffalo to Mississippi
Explore the most affordable flight options available from Buffalo to Mississippi. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 11, 2025.

This United Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/48:20 amBUF - MEM
1 stop7h 25mUnited Airlines
Thu 10/92:48 pmMEM - BUF
1 stop5h 25mUnited Airlines
Deal found 9/10$231
This Delta deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/26:15 amBUF - MEM
1 stop4h 35mDelta
Wed 10/810:33 amMEM - BUF
1 stop3h 43mDelta
Deal found 9/10$240
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/411:46 amBUF - MEM
1 stop6h 02mAmerican Airlines
Thu 10/95:27 pmMEM - BUF
1 stop5h 08mAmerican Airlines
Deal found 9/10$259
This American Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/26:00 amBUF - MEM
1 stop5h 48mAmerican Airlines
Sun 10/57:03 pmMEM - BUF
1 stop4h 09mAmerican Airlines
Deal found 9/11$271
This Kiwi.com deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/26:22 pmBUF - MEM
2 stops21h 55mMultiple Airlines
Sun 10/58:04 pmMEM - BUF
1 stop18h 59mMultiple Airlines
Deal found 9/11$276
This Delta deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/15:14 pmBUF - MOB
1 stop6h 34mDelta
Sun 11/25:43 amMOB - BUF
1 stop4h 18mDelta
Deal found 9/11$299
This Southwest deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/26:20 amBUF - MEM
2 stops7h 50mSouthwest
Wed 10/84:35 pmMEM - BUF
1 stop4h 40mSouthwest
Deal found 9/10$310
This American Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/206:50 pmBUF - MOB
1 stop5h 20mAmerican Airlines
Tue 9/301:52 pmMOB - BUF
1 stop6h 51mAmerican Airlines
Deal found 9/11$329
This Kiwi.com deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/256:22 pmBUF - MEM
2 stops30h 28mMultiple Airlines
Sun 9/287:00 amMEM - BUF
1 stop9h 22mMultiple Airlines
Deal found 9/11$336
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/311:14 pmBUF - BTR
1 stop5h 04mAmerican Airlines
Sun 11/25:27 pmBTR - BUF
1 stop5h 41mAmerican Airlines
Deal found 9/10$337
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/236:00 amBUF - MOB
2 stops11h 33mAmerican Airlines
Tue 9/306:40 amMOB - BUF
2 stops10h 58mAmerican Airlines
Deal found 9/10$339
This United Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/97:07 amBUF - MEM
1 stop4h 49mUnited Airlines
Mon 10/132:48 pmMEM - BUF
1 stop18h 05mUnited Airlines
Deal found 9/10$344

Cheapflights Fare Finder

 
Customize your flight search to find flights from Buffalo to Mississippi that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 11, 2025.
Use the filters below to find and compare flights from Buffalo to Mississippi that are best for you.

Fly from

Buffalo

Fly to

Mississippi

Route

Depart

Return

Price

BuffaloMemphis

BUF - MEM

BUFMEM

Buffalo

Thu 10/2

6:15 am-9:50 am

1 stop4h 35m

Memphis

Wed 10/8

10:33 am-3:16 pm

1 stop3h 43m

$240

BuffaloMemphis

BUF - MEM

BUFMEM

Buffalo

Sat 10/4

7:40 am-1:09 pm

1 stop6h 29m

Memphis

Thu 10/9

3:35 pm-11:35 pm

1 stop7h 00m

$259

BuffaloBaton Rouge

BUF - BTR

BUFBTR

Buffalo

Sat 1/10

2:00 pm-8:09 pm

1 stop7h 09m

Baton Rouge Ryan

Wed 1/14

5:00 pm-11:57 pm

1 stop5h 57m

$271

BuffaloBaton Rouge

BUF - BTR

BUFBTR

Buffalo

Sat 1/10

5:28 pm-10:14 pm

1 stop5h 46m

Baton Rouge Ryan

Wed 1/14

2:18 pm-10:30 pm

1 stop7h 12m

$271

BuffaloMemphis

BUF - MEM

BUFMEM

Buffalo

Thu 10/2

6:22 pm-3:17 pm

2 stops21h 55m

Memphis

Sun 10/5

8:04 pm-4:03 pm

1 stop18h 59m

$276

BuffaloMemphis

BUF - MEM

BUFMEM

Buffalo

Thu 10/2

6:00 am-10:48 am

1 stop5h 48m

Memphis

Sun 10/5

7:03 pm-12:12 am

1 stop4h 09m

$281

BuffaloMobile

BUF - MOB

BUFMOB

Buffalo

Sat 11/1

5:14 pm-10:48 pm

1 stop6h 34m

Mobile

Sun 11/2

5:43 am-11:01 am

1 stop4h 18m

$299

BuffaloMemphis

BUF - MEM

BUFMEM

Buffalo

Thu 10/2

6:20 am-1:10 pm

2 stops7h 50m

Memphis

Wed 10/8

4:35 pm-10:15 pm

1 stop4h 40m

$310

BuffaloMobile

BUF - MOB

BUFMOB

Buffalo

Sat 9/20

6:50 pm-11:10 pm

1 stop5h 20m

Mobile

Tue 9/30

1:52 pm-9:43 pm

1 stop6h 51m

$329

BuffaloMobile

BUF - MOB

BUFMOB

Buffalo

Tue 9/23

6:45 pm-11:11 pm

1 stop5h 26m

Mobile

Tue 9/30

6:40 am-4:01 pm

2 stops8h 21m

$334

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/10

Showing 1-10 of 54 results
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Best time to book a flight from Buffalo to Mississippi

Have a flexible travel schedule? Discover the best time to fly to Mississippi from Buffalo with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Buffalo to Mississippi

What is the cheapest month to book a flight from Buffalo to Mississippi?

Currently, January is the cheapest month in which you can book a flight from Buffalo to Mississippi (average of $371). Flying from Buffalo to Mississippi in March is currently the most expensive (average of $448). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from BUF to MS?

Find hourly flight availability from Buffalo to Mississippi. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 11, 2025.

When flying from Buffalo to Mississippi, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Reviews of airlines servicing Mississippi

Get insights into the airlines that provide service to Mississippi. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Mississippi. Reviews last updated September 11, 2025.
Peruse reviews from past customers who have flown with Delta and American Airlines from Buffalo to Mississippi to help guide your decision. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,960 reviews

Entertainment

7.9

Food

7.3

Overall

8.0

Comfort

7.9

Boarding

8.2

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.
Delta
8.0
Very good
7,960 reviews
Delta
8.0
Very good
7,960 reviews

Entertainment

7.9

Food

7.3

Overall

8.0

Comfort

7.9

Boarding

8.2

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,960 reviews

Entertainment

7.9

Food

7.3

Overall

8.0

Comfort

7.9

Boarding

8.2

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.

Related info for your journey

Find useful and relevant information for your journey from Buffalo to Mississippi. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Buffalo to Mississippi?

    If you book a flight to Mississippi from Buffalo, you will be flying from Buffalo, which is the city’s only airport. Buffalo (BUF) is located 8.3 mi from the center of Buffalo.

  • How long is the flight from Buffalo to Mississippi?

    A quick flight from Buffalo to Mississippi can take about 4h 35m. Delta provides one of the quickest options available for as low as $240. There are 812 mi between Buffalo and Mississippi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines to fly from Buffalo to Mississippi one-way?

    One-way options have recently been found by users for as low as $110 on American Airlines. Other airlines that offer cheap prices include Delta from $150 and United Airlines from $190 one-way.

  • What are the most popular routes from Buffalo to Mississippi?

    The most popular flight routes from Buffalo to Mississippi are Buffalo - Memphis, Buffalo - Gulfport Biloxi Regional and Buffalo - Baton Rouge Ryan.

  • Can I find deals for flights from Buffalo to Mississippi that include hotel bookings?

    Yes. In addition to deals on Buffalo to Mississippi flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Buffalo to Mississippi?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Buffalo to Mississippi.

  • Can I find deals for business class flights from Buffalo to Mississippi?

    Yes. Cheapflights offers flight deals from Buffalo to Mississippi by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Buffalo to Mississippi?

    Currently, January is the cheapest month in which you can book a flight from Buffalo to Mississippi (average of $371). Flying from Buffalo to Mississippi in March is currently the most expensive (average of $448). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Buffalo to Mississippi

See prices for flight routes from nearby airports that may be better suited for you.
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Top 2 airlines flying from Buffalo to Mississippi

Discover the top 2 airlines that operate flights from Buffalo to Mississippi. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 11, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$270Average$465FlexibilityNo cancel feeOn-time71%
DeltaCheapest$278Average$459FlexibilityNo cancel feeOn-timeN/A

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