$131+ Cheap flights from Mississippi to Buffalo (BUF)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/15. Fares are subject to change and may not be available on all flights or dates of travel.
JAN — BUF
May 29 — Jun 51
Round-trip
1 adult, Economy
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Find cheap flights from Mississippi to Buffalo with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Cheapest flights from Mississippi to BuffaloExplore the most affordable flight options available from Mississippi to Buffalo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 29, 2026.
Explore the most affordable flight options available from Mississippi to Buffalo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 29, 2026.
This Kiwi.com deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/85:37 pm
MEM
- BUF
1 stop24h 35m
Multiple Airlines
Mon 6/152:50 pm
BUF
- MEM
1 stop21h 05m
Multiple Airlines
Deal found 4/24![Multiple Airlines logo]()
$251
This Kiwi.com deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/211:59 am
MEM
- BUF
1 stop24h 55m
Frontier
Mon 6/82:49 pm
BUF
- MEM
1 stop21h 25m
Frontier
Deal found 4/27![Frontier logo]()
$285
This Kiwi.com deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/257:54 pm
MEM
- BUF
2 stops13h 47m
Multiple Airlines
Mon 6/17:52 pm
BUF
- MEM
1 stop21h 40m
Multiple Airlines
Deal found 4/27![Multiple Airlines logo]()
$301
This Kiwi.com deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/1611:51 am
MEM
- BUF
1 stop25h 04m
Multiple Airlines
Sat 6/2012:29 pm
BUF
- MEM
2 stops20h 16m
Multiple Airlines
Deal found 4/28![Multiple Airlines logo]()
$302
This Kiwi.com deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/25:37 pm
MEM
- BUF
2 stops19h 17m
Multiple Airlines
Mon 6/82:49 pm
BUF
- MEM
1 stop21h 25m
Multiple Airlines
Deal found 4/27![Multiple Airlines logo]()
$305
This Kiwi.com deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/1611:51 am
MEM
- BUF
1 stop25h 04m
Frontier
Sat 6/2012:29 pm
BUF
- MEM
1 stop23h 26m
Frontier
Deal found 4/28![Frontier logo]()
$309
This Kiwi.com deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/185:37 pm
MEM
- BUF
2 stops16h 04m
Multiple Airlines
Wed 5/202:49 pm
BUF
- MEM
1 stop26h 50m
Multiple Airlines
Deal found 4/28![Multiple Airlines logo]()
$314
This Delta deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/36:02 pm
GPT
- BUF
1 stop4h 57m
Delta
Wed 6/106:00 am
BUF
- GPT
1 stop4h 21m
Delta
Deal found 4/29![Delta logo]()
$317
This Kiwi.com deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/87:03 pm
MEM
- BUF
2 stops38h 38m
Multiple Airlines
Fri 5/297:52 pm
BUF
- MEM
1 stop21h 40m
Multiple Airlines
Deal found 4/28![Multiple Airlines logo]()
$320
This Delta deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/46:02 pm
GPT
- BUF
1 stop4h 57m
Delta
Wed 6/106:00 am
BUF
- GPT
1 stop4h 21m
Delta
Deal found 4/29![Delta logo]()
$328
This Kiwi.com deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/155:37 pm
MEM
- BUF
1 stop19h 15m
Multiple Airlines
Sun 5/177:44 pm
BUF
- MEM
2 stops12h 31m
Multiple Airlines
Deal found 4/27![Multiple Airlines logo]()
$336
This Delta deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/46:02 pm
GPT
- BUF
1 stop4h 57m
Delta
Mon 6/86:00 am
BUF
- GPT
1 stop4h 21m
Delta
Deal found 4/29![Delta logo]()
$339
Best flights from Mississippi to BuffaloDiscover carefully curated flight deals from Mississippi to Buffalo that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 29, 2026.
Discover carefully curated flight deals from Mississippi to Buffalo that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 29, 2026.
This Kiwi.com deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/1611:51 am
MEM
- BUF
1 stop25h 04m
Multiple Airlines
Sat 6/2012:29 pm
BUF
- MEM
2 stops20h 16m
Multiple Airlines
Deal found 4/28![Multiple Airlines logo]()
$302
This Delta deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/86:00 pm
GPT
- BUF
1 stop4h 59m
Delta
Wed 7/156:00 am
BUF
- GPT
1 stop4h 19m
Delta
Deal found 4/27![Delta logo]()
$354
This Southwest deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/28:10 am
MEM
- BUF
2 stops9h 05m
Southwest
Mon 6/84:10 pm
BUF
- MEM
2 stops8h 45m
Southwest
Deal found 4/27![Southwest logo]()
$371
This American Airlines deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/116:26 am
JAN
- BUF
1 stop4h 53m
American Airlines
Tue 6/164:55 pm
BUF
- JAN
1 stop6h 45m
American Airlines
Deal found 4/26![American Airlines logo]()
$399
This United Airlines deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/122:00 pm
BTR
- BUF
2 stops8h 33m
United Airlines
Sat 5/165:55 pm
BUF
- BTR
2 stops20h 28m
United Airlines
Deal found 4/26![United Airlines logo]()
$569
This Delta deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/293:48 pm
BTR
- BUF
1 stop7h 11m
Delta
Mon 6/16:15 am
BUF
- BTR
1 stop7h 34m
Delta
Deal found 4/25![Delta logo]()
$360
This Delta deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/154:00 pm
BTR
- BUF
1 stop6h 59m
Delta
Sun 7/265:12 pm
BUF
- BTR
1 stop5h 44m
Delta
Deal found 4/24![Delta logo]()
$360
This Southwest deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/82:30 pm
MEM
- BUF
2 stops8h 40m
Southwest
Mon 6/155:55 pm
BUF
- MEM
2 stops7h 00m
Southwest
Deal found 4/24![Southwest logo]()
$401
This American Airlines deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/306:44 am
BTR
- BUF
1 stop5h 10m
American Airlines
Fri 7/105:25 pm
BUF
- BTR
1 stop5h 57m
American Airlines
Deal found 4/26![American Airlines logo]()
$435
This Southwest deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/245:15 am
MEM
- BUF
1 stop4h 10m
Southwest
Thu 7/3011:00 am
BUF
- MEM
1 stop6h 30m
Southwest
Deal found 4/27![Southwest logo]()
$407
This Delta deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/2912:59 pm
JAN
- BUF
1 stop4h 45m
Delta
Mon 6/16:15 am
BUF
- JAN
1 stop6h 57m
Delta
Deal found 4/25![Delta logo]()
$391
This Southwest deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/311:20 am
MEM
- BUF
1 stop6h 05m
Southwest
Sat 9/54:35 pm
BUF
- MEM
1 stop4h 20m
Southwest
Deal found 4/24![Southwest logo]()
$407
This American Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/136:00 am
BTR
- BUF
2 stops9h 42m
American Airlines
Sun 5/176:00 am
BUF
- BTR
1 stop6h 31m
American Airlines
Deal found 4/28![American Airlines logo]()
$448
This Delta deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/18:30 am
MEM
- BUF
1 stop6h 20m
Delta
Fri 6/56:15 am
BUF
- MEM
1 stop5h 20m
Delta
Deal found 4/24![Delta logo]()
$408
This Southwest deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/165:50 am
MEM
- BUF
2 stops8h 55m
Southwest
Sat 6/202:40 pm
BUF
- MEM
2 stops9h 15m
Southwest
Deal found 4/28![Southwest logo]()
$413
This American Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/304:35 pm
MOB
- BUF
1 stop5h 05m
American Airlines
Sun 9/65:22 am
BUF
- MOB
2 stops7h 58m
American Airlines
Deal found 4/28![American Airlines logo]()
$468
This United Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/98:45 am
MOB
- BUF
2 stops11h 16m
United Airlines
Mon 5/112:45 pm
BUF
- MOB
1 stop6h 51m
United Airlines
Deal found 4/28![United Airlines logo]()
$575
This Delta deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/3011:46 am
AEX
- BUF
2 stops10h 46m
Delta
Wed 7/86:05 am
BUF
- AEX
2 stops11h 22m
Delta
Deal found 4/25![Delta logo]()
$419
This Southwest deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/32:30 pm
MEM
- BUF
2 stops8h 40m
Southwest
Mon 7/64:05 pm
BUF
- MEM
2 stops8h 50m
Southwest
Deal found 4/26![Southwest logo]()
$427
This American Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/136:09 pm
GPT
- BUF
1 stop4h 41m
American Airlines
Sun 5/177:28 pm
BUF
- GPT
1 stop5h 30m
American Airlines
Deal found 4/28![American Airlines logo]()
$472
This United Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/189:00 am
JAN
- BUF
2 stops13h 52m
United Airlines
Wed 8/197:00 am
BUF
- JAN
2 stops13h 28m
United Airlines
Deal found 4/28![United Airlines logo]()
$584
This Delta deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/235:10 pm
MOB
- BUF
1 stop5h 49m
Delta
Sat 5/3012:31 pm
BUF
- MOB
1 stop4h 49m
Delta
Deal found 4/25![Delta logo]()
$422
This Southwest deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/266:00 am
MEM
- BUF
2 stops8h 20m
Southwest
Thu 5/284:00 pm
BUF
- MEM
2 stops8h 25m
Southwest
Deal found 4/27![Southwest logo]()
$430
This American Airlines deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/2212:42 pm
MOB
- BUF
1 stop4h 59m
American Airlines
Fri 5/2912:51 pm
BUF
- MOB
2 stops9h 45m
American Airlines
Deal found 4/24![American Airlines logo]()
$506
This United Airlines deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/302:05 pm
BTR
- BUF
2 stops8h 54m
United Airlines
Fri 7/105:52 pm
BUF
- BTR
2 stops24h 42m
United Airlines
Deal found 4/26![United Airlines logo]()
$627
This American Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/224:21 pm
JAN
- BUF
2 stops6h 35m
American Airlines
Mon 6/294:55 pm
BUF
- JAN
1 stop6h 45m
American Airlines
Deal found 4/29![American Airlines logo]()
$506
This Southwest deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/271:00 pm
JAN
- BUF
2 stops8h 15m
Southwest
Fri 5/298:50 am
BUF
- JAN
1 stop11h 15m
Southwest
Deal found 4/27![Southwest logo]()
$464
This Delta deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/95:00 pm
JAN
- BUF
1 stop5h 59m
Delta
Wed 5/1312:18 pm
BUF
- JAN
1 stop4h 57m
Delta
Deal found 4/24![Delta logo]()
$487
This American Airlines deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/1210:07 am
AEX
- BUF
2 stops10h 57m
American Airlines
Sat 5/1610:44 am
BUF
- AEX
2 stops12h 53m
American Airlines
Deal found 4/27![American Airlines logo]()
$521
This United Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/3012:58 pm
MOB
- BUF
1 stop9h 54m
United Airlines
Sun 9/67:00 am
BUF
- MOB
2 stops10h 09m
United Airlines
Deal found 4/28![United Airlines logo]()
$696
Last-minute flights from Mississippi to BuffaloDiscover last-minute flight deals from Mississippi to Buffalo. Data last updated April 29, 2026 and is based on user searches.
Discover last-minute flight deals from Mississippi to Buffalo. Data last updated April 29, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/87:03 pm
MEM
- BUF
2 stops38h 38m
Multiple Airlines
Fri 5/297:52 pm
BUF
- MEM
1 stop21h 40m
Multiple Airlines
Deal found 4/28![Multiple Airlines logo]()
$320
This Kiwi.com deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/155:37 pm
MEM
- BUF
1 stop19h 15m
Multiple Airlines
Sun 5/177:44 pm
BUF
- MEM
2 stops12h 31m
Multiple Airlines
Deal found 4/27![Multiple Airlines logo]()
$336
This Kiwi.com deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/185:37 pm
MEM
- BUF
2 stops16h 04m
Multiple Airlines
Wed 5/202:49 pm
BUF
- MEM
1 stop26h 50m
Multiple Airlines
Deal found 4/28![Multiple Airlines logo]()
$314
This United Airlines deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/182:16 pm
MEM
- BUF
1 stop5h 45m
United Airlines
Tue 5/196:00 am
BUF
- MEM
1 stop6h 06m
United Airlines
Deal found 4/27![United Airlines logo]()
$350
This United Airlines deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/182:16 pm
MEM
- BUF
1 stop5h 45m
United Airlines
Wed 5/207:00 am
BUF
- MEM
1 stop4h 54m
United Airlines
Deal found 4/27![United Airlines logo]()
$355
This Southwest deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/184:25 pm
MEM
- BUF
2 stops5h 55m
Southwest
Wed 5/206:55 pm
BUF
- MEM
1 stop4h 55m
Southwest
Deal found 4/27![Southwest logo]()
$396
This Kiwi.com deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/257:54 pm
MEM
- BUF
2 stops13h 47m
Multiple Airlines
Mon 6/17:52 pm
BUF
- MEM
1 stop21h 40m
Multiple Airlines
Deal found 4/27![Multiple Airlines logo]()
$301
This Delta deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/275:05 pm
JAN
- BUF
1 stop5h 54m
Delta
Fri 5/294:55 pm
BUF
- JAN
1 stop4h 43m
Delta
Deal found 4/27![Delta logo]()
$371
This Delta deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/293:48 pm
BTR
- BUF
1 stop7h 11m
Delta
Mon 6/16:15 am
BUF
- BTR
1 stop7h 34m
Delta
Deal found 4/25![Delta logo]()
$360
This Delta deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/2912:59 pm
JAN
- BUF
1 stop4h 45m
Delta
Mon 6/16:15 am
BUF
- JAN
1 stop6h 57m
Delta
Deal found 4/25![Delta logo]()
$391
This American Airlines deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/316:00 am
MEM
- BUF
1 stop5h 11m
American Airlines
Tue 6/25:00 am
BUF
- MEM
1 stop5h 49m
American Airlines
Deal found 4/27![American Airlines logo]()
$371
This Kiwi.com deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/318:22 am
MEM
- BUF
1 stop9h 37m
Multiple Airlines
Tue 6/211:36 am
BUF
- MEM
2 stops32h 33m
Multiple Airlines
Deal found 4/27![Multiple Airlines logo]()
$394
One-way flights from Mississippi to BuffaloSearch for one-way flight options from Mississippi to Buffalo. Find affordable one-way fares based on user searches. Data last updated April 29, 2026.
Search for one-way flight options from Mississippi to Buffalo. Find affordable one-way fares based on user searches. Data last updated April 29, 2026.
This Kiwi.com deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/153:05 pm
MEM
- BUF
2 stops18h 50m
Multiple Airlines
Deal found 4/25![Multiple Airlines logo]()
$131
This Kiwi.com deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/155:37 pm
MEM
- BUF
1 stop19h 15m
Multiple Airlines
Deal found 4/28![Multiple Airlines logo]()
$168
This Kiwi.com deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/157:54 pm
MEM
- BUF
2 stops37h 47m
Frontier
Deal found 4/28![Frontier logo]()
$172
This Kiwi.com deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/125:37 pm
MEM
- BUF
1 stop26h 43m
Multiple Airlines
Deal found 4/28![Multiple Airlines logo]()
$179
This Kiwi.com deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/118:05 am
MEM
- BUF
2 stops25h 36m
Multiple Airlines
Deal found 4/28![Multiple Airlines logo]()
$180
This Kiwi.com deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/165:37 pm
MEM
- BUF
2 stops16h 04m
Multiple Airlines
Deal found 4/28![Multiple Airlines logo]()
$184
This Kiwi.com deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/125:37 pm
MEM
- BUF
2 stops19h 17m
Multiple Airlines
Deal found 4/28![Multiple Airlines logo]()
$189
This Kiwi.com deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/85:31 pm
GPT
- BUF
2 stops40h 10m
Multiple Airlines
Deal found 4/28![Multiple Airlines logo]()
$190
This Delta deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/276:02 pm
GPT
- BUF
1 stop4h 57m
Delta
Deal found 4/27![Delta logo]()
$199
This Kiwi.com deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/115:31 pm
GPT
- BUF
3 stops43h 23m
Multiple Airlines
Deal found 4/27![Multiple Airlines logo]()
$203
This American Airlines deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/152:56 pm
MEM
- BUF
1 stop6h 40m
American Airlines
Deal found 4/25![American Airlines logo]()
$204
This Delta deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/234:00 pm
BTR
- BUF
1 stop6h 59m
Delta
Deal found 4/26![Delta logo]()
$209
Find flight deals from Mississippi to Buffalo
Keep the following information in mind while searching for Mississippi to Buffalo flight deals. Data was last updated April 29, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $251 (Kiwi.com) |
One-way from | $131 (Kiwi.com) |
Popular in | March |
Cheapest in | September |
Average price | $540 |
Cheapflights Fare Finder
Customize your flight search to find flights from Mississippi to Buffalo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 29, 2026.
Use the filters below to find and compare flights from Mississippi to Buffalo that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
MemphisBuffalo
MEM - BUF
MEMBUF
Memphis
Tue 6/16
11:51 am-1:55 pm
1 stop25h 04m
Buffalo
Sat 6/20
12:29 pm-7:45 am
2 stops20h 16m
$302
Quickest round-trip
GulfportBuffalo
GPT - BUF
GPTBUF
Gulfport Biloxi Regional
Wed 7/8
6:00 pm-11:59 pm
1 stop4h 59m
Buffalo
Wed 7/15
6:00 am-9:19 am
1 stop4h 19m
$354
Baton RougeBuffalo
BTR - BUF
BTRBUF
Baton Rouge Ryan
Fri 5/29
3:48 pm-11:59 pm
1 stop7h 11m
Buffalo
Mon 6/1
6:15 am-12:49 pm
1 stop7h 34m
$360
Baton RougeBuffalo
BTR - BUF
BTRBUF
Baton Rouge Ryan
Wed 7/15
4:00 pm-11:59 pm
1 stop6h 59m
Buffalo
Sun 7/26
5:12 pm-9:56 pm
1 stop5h 44m
$360
MemphisBuffalo
MEM - BUF
MEMBUF
Memphis
Tue 6/2
8:10 am-6:15 pm
2 stops9h 05m
Buffalo
Mon 6/8
4:10 pm-11:55 pm
2 stops8h 45m
$371
JacksonBuffalo
JAN - BUF
JANBUF
Jackson-Evers Intl
Fri 5/29
12:59 pm-6:44 pm
1 stop4h 45m
Buffalo
Mon 6/1
6:15 am-12:12 pm
1 stop6h 57m
$391
JacksonBuffalo
JAN - BUF
JANBUF
Jackson-Evers Intl
Thu 6/11
6:26 am-12:19 pm
1 stop4h 53m
Buffalo
Tue 6/16
4:55 pm-10:40 pm
1 stop6h 45m
$399
MemphisBuffalo
MEM - BUF
MEMBUF
Memphis
Mon 6/8
2:30 pm-12:10 am
2 stops8h 40m
Buffalo
Mon 6/15
5:55 pm-11:55 pm
2 stops7h 00m
$401
MemphisBuffalo
MEM - BUF
MEMBUF
Memphis
Fri 7/24
5:15 am-10:25 am
1 stop4h 10m
Buffalo
Thu 7/30
11:00 am-4:30 pm
1 stop6h 30m
$407
MemphisBuffalo
MEM - BUF
MEMBUF
Memphis
Thu 9/3
11:20 am-6:25 pm
1 stop6h 05m
Buffalo
Sat 9/5
4:35 pm-7:55 pm
1 stop4h 20m
$407
Showing 1-10 of 54 resultsSorted by cheapest first
Best time to book a flight from Mississippi to Buffalo
Have a flexible travel schedule? Discover the best time to fly to Buffalo from Mississippi with our price prediction graph.
MEM-BUF
GPT-BUF
BTR-BUF
MOB-BUF
AEX-BUF
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Mississippi to Buffalo
USMS-BUF
MEM-BUF
GPT-BUF
BTR-BUF
MOB-BUF
How much does it cost to fly round-trip from Mississippi to Buffalo?
Related info for your journey
Find useful and relevant information for your journey from Mississippi to Buffalo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Buffalo?
Book flights to Buffalo if you plan to visit one of these locationsLockport
Cheektowaga
Batavia
Williamsville
Orchard Park
Eden
Amherst
West Seneca
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Buffalo flight routes
Complete your trip
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Alternative routes for Mississippi to Buffalo
See prices for flight routes from nearby airports that may be better suited for you.
Other flights to Buffalo
Explore flights to Buffalo departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on April 29, 2026.
Complete your trip
Complete your trip to Buffalo by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Mississippi to Buffalo by cabin class
Find flights from Mississippi to Buffalo, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Mississippi and Buffalo flights
Browse other Mississippi and Buffalo flight options. Last updated on April 29, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Mississippi to Buffalo flights
Consider these flights traveling from Mississippi to Buffalo.
Top 2 airlines flying from Mississippi to Buffalo
Discover the top 2 airlines that operate flights from Mississippi to Buffalo. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 29, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$199 | Average$447 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$310 | Average$488 | FlexibilityNo cancel fee | On-time71% |