HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Minnesota

$80+ Cheap flights from Knoxville (TYS) to Minnesota

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/23. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — MSP
Feb 26 — Mar 51
Thu 2/26
Thu 3/5
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Knoxville to Minnesota with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Knoxville to Minnesota

Cheapest flights from Knoxville to Minnesota
Explore the most affordable flight options available from Knoxville to Minnesota. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 27, 2026.

This Delta deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/276:35 am
TYS
-
RST
1 stop5h 23m
Delta
Tue 3/34:37 pm
RST
-
TYS
1 stop5h 35m
Delta
Deal found 1/27$258
This American Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/277:51 am
TYS
-
RST
1 stop4h 11m
American Airlines
Tue 3/37:00 am
RST
-
TYS
2 stops7h 30m
American Airlines
Deal found 1/27$264
This Delta deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/106:30 am
TYS
-
FSD
1 stop4h 52m
Delta
Sat 2/144:19 pm
FSD
-
TYS
1 stop5h 53m
Delta
Deal found 1/26$279
This Frontier deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/276:51 pm
TYS
-
MSP
1 stop6h 06m
Frontier
Mon 3/26:45 am
MSP
-
TYS
1 stop11h 33m
Frontier
Deal found 1/26$285
This Southwest deal was found by Cheapflights users on 1/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/25:40 pm
TYS
-
MSP
1 stop5h 55m
Southwest
Sat 5/96:15 am
MSP
-
TYS
1 stop4h 25m
Southwest
Deal found 1/24$293
This American Airlines deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/75:44 am
TYS
-
FSD
1 stop8h 17m
American Airlines
Sat 5/166:00 am
FSD
-
TYS
1 stop8h 19m
American Airlines
Deal found 1/26$295
This Southwest deal was found by Cheapflights users on 1/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/166:35 am
TYS
-
MSP
2 stops9h 25m
Southwest
Sat 4/186:15 am
MSP
-
TYS
1 stop4h 25m
Southwest
Deal found 1/25$298
This Delta deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/276:35 am
TYS
-
MSP
Nonstop2h 38m
Delta
Mon 3/27:50 pm
MSP
-
TYS
Nonstop2h 22m
Delta
Deal found 1/27$299
This American Airlines deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/297:33 pm
TYS
-
MSP
1 stop5h 26m
American Airlines
Sat 5/22:59 pm
MSP
-
TYS
1 stop7h 57m
American Airlines
Deal found 1/26$319
This Kiwi.com deal was found by Cheapflights users on 1/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/225:56 pm
TYS
-
MSP
2 stops23h 59m
Multiple Airlines
Sun 3/18:17 pm
MSP
-
TYS
1 stop21h 14m
Multiple Airlines
Deal found 1/24$321
This Southwest deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/238:10 am
TYS
-
MSP
2 stops9h 05m
Southwest
Tue 6/307:05 am
MSP
-
TYS
1 stop4h 00m
Southwest
Deal found 1/27$324
This Kiwi.com deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/168:13 pm
TYS
-
MSP
1 stop27h 46m
Frontier
Fri 2/206:45 am
MSP
-
TYS
1 stop11h 42m
Frontier
Deal found 1/26$337

Find flight deals from Knoxville to Minnesota

Keep the following information in mind while searching for Knoxville to Minnesota flight deals. Data was last updated January 27, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$258
(Delta)

One-way from

$80
(Frontier)

Popular in

March

Cheapest in

June

Average price

$419

Good round-trip deal

$419 or less

Good one-way deal

$230 or less
Provider with most accurate pricing for Knoxville McGhee Tyson-Minneapolis St Paul flight deals.
Search Deals
Provider most trusted by Cheapflights users for Knoxville McGhee Tyson-Minneapolis St Paul flights.
Search Deals
From Knoxville McGhee Tyson to Minnesota
Search Deals
One-way flight from Knoxville McGhee Tyson to Minnesota
Search Deals
Highest demand for flights based on searches. 29% potential increase in price ($181 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 10% potential price decrease ($43 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in January 2026
Search Deals
Price to beat on a round-trip flight from Knoxville McGhee Tyson to Minnesota.
Search Deals
Price to beat on a one-way flight from Knoxville McGhee Tyson to Minnesota.
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Knoxville to Minnesota that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 27, 2026.
Use the filters below to find and compare flights from Knoxville to Minnesota that are best for you.

Fly from

Knoxville

Fly to

Minnesota

Route

Depart

Return

Price

KnoxvilleRochester

TYS - RST

TYSRST

Knoxville McGhee Tyson

Fri 2/27

6:35 am-10:58 am

1 stop5h 23m

Rochester

Tue 3/3

4:37 pm-11:12 pm

1 stop5h 35m

$258

KnoxvilleRochester

TYS - RST

TYSRST

Knoxville McGhee Tyson

Fri 2/27

7:51 am-11:02 am

1 stop4h 11m

Rochester

Tue 3/3

7:00 am-3:30 pm

2 stops7h 30m

$264

KnoxvilleSioux Falls

TYS - FSD

TYSFSD

Knoxville McGhee Tyson

Tue 2/10

5:40 am-12:22 pm

2 stops7h 42m

Sioux Falls Joe Foss Field

Sat 2/14

4:19 pm-11:12 pm

1 stop5h 53m

$284

KnoxvilleMinneapolis

TYS - MSP

TYSMSP

Knoxville McGhee Tyson

Fri 2/27

6:51 pm-11:57 pm

1 stop6h 06m

Minneapolis St Paul

Mon 3/2

6:45 am-7:18 pm

1 stop11h 33m

$285

KnoxvilleMinneapolis

TYS - MSP

TYSMSP

Knoxville McGhee Tyson

Sat 5/2

5:40 pm-10:35 pm

1 stop5h 55m

Minneapolis St Paul

Sat 5/9

6:15 am-11:40 am

1 stop4h 25m

$293

KnoxvilleMinneapolis

TYS - MSP

TYSMSP

Knoxville McGhee Tyson

Thu 4/16

6:35 am-3:00 pm

2 stops9h 25m

Minneapolis St Paul

Sat 4/18

6:15 am-11:40 am

1 stop4h 25m

$298

KnoxvilleMinneapolis

TYS - MSP

TYSMSP

Knoxville McGhee Tyson

Thu 2/26

6:35 am-8:13 am

Nonstop2h 38m

Minneapolis St Paul

Tue 3/3

7:50 pm-11:12 pm

Nonstop2h 22m

$299

KnoxvilleMinneapolis

TYS - MSP

TYSMSP

Knoxville McGhee Tyson

Fri 2/27

6:35 am-8:13 am

Nonstop2h 38m

Minneapolis St Paul

Mon 3/2

7:50 pm-11:12 pm

Nonstop2h 22m

$299

KnoxvilleMinneapolis

TYS - MSP

TYSMSP

Knoxville McGhee Tyson

Thu 4/16

6:13 am-7:42 am

Nonstop2h 29m

Minneapolis St Paul

Sat 4/18

7:45 pm-10:59 pm

Nonstop2h 14m

$299

KnoxvilleMinneapolis

TYS - MSP

TYSMSP

Knoxville McGhee Tyson

Wed 4/29

6:13 am-7:42 am

Nonstop2h 29m

Minneapolis St Paul

Sat 5/2

7:45 pm-10:59 pm

Nonstop2h 14m

$299

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/27

Showing 1-10 of 49 results
1
2
3
...
5

Best time to book a flight from Knoxville to Minnesota

Have a flexible travel schedule? Discover the best time to fly to Minnesota from Knoxville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Knoxville to Minnesota

What is the cheapest month to book a flight from Knoxville to Minnesota?

Currently, June is the cheapest month in which you can book a flight from Knoxville to Minnesota (average of $56). Flying from Knoxville to Minnesota in October is currently the most expensive (average of $269). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from TYS to MN?

Find hourly flight availability from Knoxville to Minnesota. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated January 27, 2026.

When flying from Knoxville to Minnesota, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Weekly flight availability from Knoxville to Minnesota

Explore weekly flight availability from Knoxville to Minnesota. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated January 27, 2026.

The most flights from TYS to USMN are scheduled on a Monday (2 on average). You will have fewer flight options on Monday, which is when the least amount of flights are scheduled (2 on average).

How much does it cost to fly round-trip from Knoxville to Minnesota?

Reviews of airlines servicing Minnesota

Get insights into the airlines that provide service to Minnesota. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Minnesota. Reviews last updated January 27, 2026.
Read reviews from past customers who have flown Delta, United Airlines, and American Airlines from Knoxville to Minnesota. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,119 reviews

Overall

7.9

Comfort

7.9

Boarding

8.1

Entertainment

7.8

Crew

8.5

Food

7.2

Reviews

1 / 20
8.0
Excellent

Lane,Nov 2025

MEM - ATL

The crew was very friendly, but they only came around and offered the better Delta Comfort snacks one time. I thought they would come around more frequently on a 5 hour flight. They did do two beverage services though, which was nice.
Delta
7.9
Good
8,119 reviews
Delta
7.9
Good
8,119 reviews

Overall

7.9

Comfort

7.9

Boarding

8.1

Entertainment

7.8

Crew

8.5

Food

7.2

Reviews

1 / 20
8.0
Excellent

Lane,Nov 2025

MEM - ATL

The crew was very friendly, but they only came around and offered the better Delta Comfort snacks one time. I thought they would come around more frequently on a 5 hour flight. They did do two beverage services though, which was nice.
United Airlines
7.4
Good
9,205 reviews
Delta
7.9
Good
8,119 reviews

Overall

7.9

Comfort

7.9

Boarding

8.1

Entertainment

7.8

Crew

8.5

Food

7.2

Reviews

1 / 20
8.0
Excellent

Lane,Nov 2025

MEM - ATL

The crew was very friendly, but they only came around and offered the better Delta Comfort snacks one time. I thought they would come around more frequently on a 5 hour flight. They did do two beverage services though, which was nice.
American Airlines
7.2
Good
11,197 reviews
Delta
7.9
Good
8,119 reviews

Overall

7.9

Comfort

7.9

Boarding

8.1

Entertainment

7.8

Crew

8.5

Food

7.2

Reviews

1 / 20
8.0
Excellent

Lane,Nov 2025

MEM - ATL

The crew was very friendly, but they only came around and offered the better Delta Comfort snacks one time. I thought they would come around more frequently on a 5 hour flight. They did do two beverage services though, which was nice.
Allegiant Air
7.2
Good
706 reviews
Delta
7.9
Good
8,119 reviews

Overall

7.9

Comfort

7.9

Boarding

8.1

Entertainment

7.8

Crew

8.5

Food

7.2

Reviews

1 / 20
8.0
Excellent

Lane,Nov 2025

MEM - ATL

The crew was very friendly, but they only came around and offered the better Delta Comfort snacks one time. I thought they would come around more frequently on a 5 hour flight. They did do two beverage services though, which was nice.

Related info for your journey

Find useful and relevant information for your journey from Knoxville to Minnesota. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Knoxville to Minnesota?

    Located just 11.3 mi from the city center, Knoxville McGhee Tyson (TYS) is the airport most travelers will use when flying to Minnesota from Knoxville.

  • How long is the flight from Knoxville to Minnesota?

    For as low as $264, Delta can have you in Minnesota from Knoxville in 4h 11m. The distance from Knoxville to Minnesota is about 718 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines to fly from Knoxville to Minnesota one-way?

    For one-way options, check prices for Allegiant Air. According to our data, you can fly for as low as $48. Users have also found prices from $107 and $189 on Frontier and United Airlines, respectively.

  • What are the most popular routes from Knoxville to Minnesota?

    The most popular flight routes from Knoxville to Minnesota are Knoxville McGhee Tyson - Minneapolis St Paul, Knoxville McGhee Tyson - Fargo Hector Field and Knoxville McGhee Tyson - Sioux Falls Joe Foss Field.

  • What are the most reliable airlines from Knoxville to Minnesota?

    Before booking your flight to Minnesota from Knoxville, check out the most reliable airlines to get you to your destination on time: Air France (100%), Virgin Atlantic (95%), Delta( 89%).

  • What are the cheapest flights from Knoxville to Minnesota?

    Looking at all options, your cheapest flight can be booked for $159. While the most popular route (Knoxville McGhee Tyson - Minneapolis St Paul) can be booked for $293 on average, our data indicates $474 when flying from Knoxville to Minnesota.

  • Can I find deals for flights from Knoxville to Minnesota that include hotel bookings?

    Yes. In addition to deals on Knoxville to Minnesota flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to Minnesota?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Minnesota.

  • Can I find deals for business class flights from Knoxville to Minnesota?

    Yes. Cheapflights offers flight deals from Knoxville to Minnesota by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Knoxville to Minnesota?

    Currently, June is the cheapest month in which you can book a flight from Knoxville to Minnesota (average of $56). Flying from Knoxville to Minnesota in October is currently the most expensive (average of $269). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Knoxville to Minnesota

See prices for flight routes from nearby airports that may be better suited for you.
Nashville to Seattle flights
Nashville to Los Angeles flights
Memphis to Hobby flights
Nashville to Orlando flights
Knoxville to Denver flights
Nashville to John F Kennedy Intl flights
Nashville to Newark flights
Nashville to Miami flights
Nashville to Las Vegas flights
Nashville to Dallas/Fort Worth flights
Nashville to Denver flights
Nashville to Fort Lauderdale flights
Nashville to LaGuardia flights
Nashville to Hobby flights
Memphis to George Bush Intcntl flights
Memphis to Atlanta flights
Memphis to Orlando flights
Nashville to Reagan-National flights
Memphis to Las Vegas flights
Memphis to Denver flights
Memphis to LaGuardia flights
Nashville to Sky Harbor Intl flights
Nashville to O'Hare Intl flights
Chattanooga to LaGuardia flights
Nashville to George Bush Intcntl flights
Nashville to Dulles Intl flights
Memphis to John F Kennedy Intl flights
Memphis to Miami flights
Chattanooga to Orlando flights
Nashville to San Francisco flights
Knoxville to LaGuardia flights
Nashville to Boston flights
Knoxville to Hobby flights
Nashville to Tampa flights
Memphis to Dallas/Fort Worth flights
Nashville to Salt Lake City flights
Memphis to O'Hare Intl flights
Memphis to Los Angeles flights
Chattanooga to Las Vegas flights
Nashville to Honolulu flights
Memphis to Newark flights
Nashville to Baltimore flights
Knoxville to Orlando flights
Chattanooga to John F Kennedy Intl flights
Nashville to Fort Myers flights
Memphis to Seattle flights
Knoxville to George Bush Intcntl flights
Chattanooga to Newark flights
Knoxville to John F Kennedy Intl flights
Nashville to New Orleans flights

Top 4 airlines flying from Knoxville to Minnesota

Discover the top 4 airlines that operate flights from Knoxville to Minnesota. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 27, 2026.
AirlineCheapestAverageFlexibilityOn-time
Allegiant AirCheapest$84Average$129FlexibilityNo cancel feeOn-time88%
DeltaCheapest$233Average$559FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$243Average$472FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$318Average$462FlexibilityNo cancel feeOn-time71%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.