$134+ Cheap flights from Minnesota to Knoxville (TYS)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/3. Fares are subject to change and may not be available on all flights or dates of travel.
MSP — TYS
Nov 29 — Dec 61
Round-trip
1 adult, Economy
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Find cheap flights from Minnesota to Knoxville with Cheapflights
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Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Cheapest flights from Minnesota to KnoxvilleExplore the most affordable flight options available from Minnesota to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 30, 2026.
Explore the most affordable flight options available from Minnesota to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 30, 2026.
This American Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/33:48 pm -
1 stop6h 58m
Sat 12/57:44 am -
1 stop6h 52m
Deal found 10/29![American Airlines logo]()
$267
This United Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/268:00 am -
1 stop4h 50m
Thu 12/36:00 am -
1 stop7h 07m
Deal found 10/28![United Airlines logo]()
$287
This Southwest deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/265:00 am -
2 stops9h 25m
Thu 12/34:15 pm -
1 stop6h 10m
Deal found 10/28![Southwest logo]()
$292
This American Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/1411:18 am -
1 stop5h 38m
Fri 12/186:07 pm -
1 stop6h 02m
Deal found 10/29![American Airlines logo]()
$297
This Kiwi.com deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/2310:39 am -
2 stops34h 27m
Wed 12/25:14 pm -
1 stop22h 32m
Deal found 10/29![Multiple Airlines logo]()
$307
This Kiwi.com deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/2412:42 pm -
1 stop9h 41m
Tue 12/13:42 pm -
2 stops24h 03m
Deal found 10/27![Multiple Airlines logo]()
$316
This American Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/176:21 pm -
1 stop4h 29m
Wed 12/238:48 pm -
1 stop4h 41m
Deal found 10/28![American Airlines logo]()
$317
This Southwest deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/31:50 pm -
1 stop6h 00m
Sun 12/67:25 pm -
1 stop6h 20m
Deal found 10/27![Southwest logo]()
$323
This American Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/102:27 pm -
1 stop7h 59m
Tue 12/157:44 am -
1 stop11h 08m
Deal found 10/27![American Airlines logo]()
$327
This American Airlines deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/104:30 pm -
1 stop5h 21m
Sat 11/1411:33 am -
1 stop5h 17m
Deal found 10/25![American Airlines logo]()
$378
This American Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/246:07 am -
2 stops10h 22m
Wed 12/308:48 pm -
1 stop4h 26m
Deal found 10/28![American Airlines logo]()
$414
This American Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/291:02 pm -
1 stop4h 18m
Mon 11/28:52 pm -
1 stop4h 07m
Deal found 10/26![American Airlines logo]()
$453
Best flights from Minnesota to KnoxvilleDiscover carefully curated flight deals from Minnesota to Knoxville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 30, 2026.
Discover carefully curated flight deals from Minnesota to Knoxville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 30, 2026.
This Delta deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/247:45 pm -
Nonstop2h 25m
Thu 12/316:50 am -
Nonstop2h 45m
Deal found 10/28![Delta logo]()
$339
This American Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/712:36 pm -
1 stop5h 31m
Fri 1/1512:02 pm -
1 stop5h 03m
Deal found 10/26![American Airlines logo]()
$348
This Southwest deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/249:00 am -
2 stops10h 50m
Thu 12/317:55 am -
1 stop7h 55m
Deal found 10/25![Southwest logo]()
$352
This United Airlines deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/305:50 am -
1 stop6h 30m
Wed 2/35:55 pm -
1 stop4h 55m
Deal found 10/25![United Airlines logo]()
$448
This Delta deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/126:20 pm -
Nonstop2h 17m
Mon 2/157:55 am -
Nonstop2h 34m
Deal found 10/26![Delta logo]()
$339
This American Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 1/3112:36 pm -
2 stops8h 44m
Sat 2/67:50 am -
1 stop5h 14m
Deal found 10/29![American Airlines logo]()
$354
This Southwest deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/265:00 am -
2 stops9h 25m
Thu 12/31:00 pm -
2 stops10h 25m
Deal found 10/28![Southwest logo]()
$365
This Delta deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/174:25 pm -
1 stop4h 12m
Sun 2/217:55 am -
1 stop4h 08m
Deal found 10/29![Delta logo]()
$348
This Southwest deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/257:50 am -
2 stops12h 00m
Thu 12/311:00 pm -
2 stops10h 25m
Deal found 10/25![Southwest logo]()
$404
This United Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/2311:16 am -
1 stop4h 43m
Mon 11/305:40 pm -
1 stop6h 34m
Deal found 10/26![United Airlines logo]()
$469
This Delta deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/2512:45 pm -
1 stop6h 15m
Thu 12/316:50 am -
Nonstop2h 45m
Deal found 10/25![Delta logo]()
$429
This Southwest deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/2610:15 am -
2 stops10h 25m
Thu 12/317:55 am -
1 stop7h 55m
Deal found 10/29![Southwest logo]()
$451
This Delta deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/267:45 pm -
Nonstop2h 25m
Wed 12/306:00 am -
1 stop5h 08m
Deal found 10/29![Delta logo]()
$439
This United Airlines deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/1711:00 am -
1 stop5h 15m
Sat 1/25:57 pm -
1 stop6h 31m
Deal found 10/25![United Airlines logo]()
$650
Last-minute flights from Minnesota to KnoxvilleDiscover last-minute flight deals from Minnesota to Knoxville. Data last updated October 30, 2026 and is based on user searches.
Discover last-minute flight deals from Minnesota to Knoxville. Data last updated October 30, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/291:02 pm -
1 stop4h 18m
Mon 11/28:52 pm -
1 stop4h 07m
Deal found 10/26![American Airlines logo]()
$453
This American Airlines deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/104:30 pm -
1 stop5h 21m
Sat 11/1411:33 am -
1 stop5h 17m
Deal found 10/25![American Airlines logo]()
$378
This Kiwi.com deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/2310:39 am -
2 stops34h 27m
Wed 12/25:14 pm -
1 stop22h 32m
Deal found 10/29![Multiple Airlines logo]()
$307
This Kiwi.com deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/236:30 am -
1 stop15h 59m
Thu 12/39:00 pm -
2 stops18h 45m
Deal found 10/29![Multiple Airlines logo]()
$340
This Kiwi.com deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/2412:42 pm -
1 stop9h 41m
Tue 12/13:42 pm -
2 stops24h 03m
Deal found 10/27![Multiple Airlines logo]()
$316
This American Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/245:18 am -
1 stop9h 44m
Tue 12/18:50 pm -
1 stop12h 39m
Deal found 10/27![American Airlines logo]()
$327
This United Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/268:00 am -
1 stop4h 50m
Thu 12/36:00 am -
1 stop7h 07m
Deal found 10/28![United Airlines logo]()
$287
This Southwest deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/265:00 am -
2 stops9h 25m
Thu 12/34:15 pm -
1 stop6h 10m
Deal found 10/28![Southwest logo]()
$292
This Delta deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/266:00 pm -
Nonstop2h 17m
Thu 12/37:59 am -
Nonstop2h 41m
Deal found 10/26![Delta logo]()
$339
This American Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/275:03 pm -
1 stop5h 56m
Mon 12/78:46 pm -
1 stop12h 43m
Deal found 10/28![American Airlines logo]()
$343
This Delta deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/276:00 pm -
Nonstop2h 17m
Mon 12/77:26 pm -
1 stop6h 20m
Deal found 10/28![Delta logo]()
$349
This Delta deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/274:46 pm -
1 stop4h 26m
Fri 12/46:17 pm -
1 stop7h 29m
Deal found 10/27![Delta logo]()
$359
One-way flights from Minnesota to KnoxvilleSearch for one-way flight options from Minnesota to Knoxville. Find affordable one-way fares based on user searches. Data last updated October 30, 2026.
Search for one-way flight options from Minnesota to Knoxville. Find affordable one-way fares based on user searches. Data last updated October 30, 2026.
This American Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/36:22 pm -
1 stop4h 24m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/29![American Airlines logo]()
$134
This Kiwi.com deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/311:11 am -
2 stops46h 26m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/28![Multiple Airlines logo]()
$136
This Southwest deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/31:50 pm -
1 stop6h 00m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/28![Southwest logo]()
$144
This Kiwi.com deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/186:20 am -
1 stop10h 51m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/26![Multiple Airlines logo]()
$163
This Trip.com deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/126:40 am -
1 stop10h 03m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/27![Multiple Airlines logo]()
$180
This Southwest deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/77:25 am -
2 stops9h 35m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/25![Southwest logo]()
$185
This WAYA deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure WAYA is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/137:25 am -
1 stop9h 32m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/26![Multiple Airlines logo]()
$205
This Southwest deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/1812:55 pm -
2 stops7h 50m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/26![Southwest logo]()
$217
This Southwest deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/215:40 pm -
1 stop4h 00m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/25![Southwest logo]()
$220
This Delta deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/74:15 pm -
1 stop4h 22m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/27![Delta logo]()
$288
This Delta deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/65:10 am -
2 stops7h 18m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/27![Delta logo]()
$294
This Delta deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/84:15 pm -
1 stop4h 22m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/27![Delta logo]()
$318
Find flight deals from Minnesota to Knoxville
Keep the following information in mind while searching for Minnesota to Knoxville flight deals. Data was last updated October 30, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $267 (American Airlines) |
One-way from | $134 (American Airlines) |
Popular in | January |
Cheapest in | August |
Average price | $509 |
Good round-trip deal | $458 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Minnesota to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 30, 2026.
Use the filters below to find and compare flights from Minnesota to Knoxville that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
MinneapolisKnoxville
MSP Minneapolis St Paul - TYS Knoxville McGhee Tyson
MSPTYS
Minneapolis St Paul
Thu 12/3
6:22 pm-11:46 pm
1 stop4h 24m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$134
MinneapolisKnoxville
MSP Minneapolis St Paul - TYS Knoxville McGhee Tyson
MSPTYS
Minneapolis St Paul
Thu 12/3
1:50 pm-8:50 pm
1 stop6h 00m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$144
MinneapolisKnoxville
MSP Minneapolis St Paul - TYS Knoxville McGhee Tyson
MSPTYS
Minneapolis St Paul
Fri 12/18
12:55 pm-9:45 pm
2 stops7h 50m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$217
MinneapolisKnoxville
MSP Minneapolis St Paul - TYS Knoxville McGhee Tyson
MSPTYS
Minneapolis St Paul
Mon 12/21
5:40 pm-10:40 pm
1 stop4h 00m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$220
MinneapolisKnoxville
MSP Minneapolis St Paul - TYS Knoxville McGhee Tyson
MSPTYS
Minneapolis St Paul
Thu 11/12
6:15 am-3:00 pm
2 stops7h 45m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$255
Quickest round-trip
MinneapolisKnoxville
MSP Minneapolis St Paul - TYS Knoxville McGhee Tyson
MSPTYS
Minneapolis St Paul
Mon 12/21
7:45 pm-11:10 pm
Nonstop2h 25m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$269
MinneapolisKnoxville
MSP Minneapolis St Paul - TYS Knoxville McGhee Tyson
MSPTYS
Minneapolis St Paul
Thu 12/3
7:59 pm-11:24 pm
Nonstop2h 25m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$269
MinneapolisKnoxville
MSP Minneapolis St Paul - TYS Knoxville McGhee Tyson
MSPTYS
Minneapolis St Paul
Thu 11/5
6:15 am-12:10 pm
1 stop4h 55m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$280
DuluthKnoxville
DLH Duluth Intl - TYS Knoxville McGhee Tyson
DLHTYS
Duluth Intl
Tue 4/6
7:35 am-1:18 pm
1 stop4h 43m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$288
DuluthKnoxville
DLH Duluth Intl - TYS Knoxville McGhee Tyson
DLHTYS
Duluth Intl
Wed 4/7
4:15 pm-9:37 pm
1 stop4h 22m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$288
Showing 1-10 of 28 resultsSorted by cheapest first
Best time to book a flight from Minnesota to Knoxville
Have a flexible travel schedule? Discover the best time to fly to Knoxville from Minnesota with our price prediction graph.
MSP-TYS
RST-TYS
DLH-TYS
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Minnesota to Knoxville
USMN-TYS
MSP-TYS
RST-TYS
DLH-TYS
What is the cheapest month to book a flight from Minnesota to Knoxville?
Currently, August is the cheapest month in which you can book a flight from Minnesota to Knoxville (average of $359). Flying from Minnesota to Knoxville in January is currently the most expensive (average of $509). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from MN to TYS?
Find hourly flight availability from Minnesota to Knoxville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated October 30, 2026.
One of the essential ways to save on airfare from Minnesota to Knoxville is to remain as flexible as possible. Flights that are in the afternoon tend to be the most expensive. A flight in the morning could potentially save you up to 69% on airfare.
How much does it cost to fly round-trip from Minnesota to Knoxville?
Airfare is below average for this route at the moment.
Minnesota to Knoxville flights typically cost between $339 and $548 in December.The cheapest round-trip price found within the last 5 days was $267 on American Airlines (Dec 3-Dec 5).
How far ahead should I book a flight from Minnesota to Knoxville?
The best time to book flights from Minnesota to Knoxville is 89 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.
Related info for your journey
Find useful and relevant information for your journey from Minnesota to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Knoxville?
Book flights to Knoxville if you plan to visit one of these locationsCherokee
Morristown
Newport
Bryson City
Crossville
Murphy
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Alternative routes for Minnesota to Knoxville
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Knoxville by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Minnesota to Knoxville by cabin class
Find flights from Minnesota to Knoxville, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Other flights to Knoxville
Explore flights to Knoxville departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on October 30, 2026.
Minnesota and Knoxville flights
Browse other Minnesota and Knoxville flight options. Last updated on October 30, 2026.
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Minnesota to Knoxville flights
Consider these flights traveling from Minnesota to Knoxville.
Top 4 airlines flying from Minnesota to Knoxville
Discover the top 4 airlines that operate flights from Minnesota to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 30, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$230 | Average$428 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$267 | Average$445 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$297 | Average$412 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$299 | Average$463 | FlexibilityNo cancel fee | On-timeN/A |