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Mesa

$270+ Cheap flights from Columbia, MO (COU) to Mesa, AZ

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/6. Fares are subject to change and may not be available on all flights or dates of travel.
COU — PHX
Nov 22 — Nov 291
Sat 11/22
Sat 11/29
1 adult, Economy
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Cheap flight deals from Columbia to Mesa

Keep the following information in mind while searching for Columbia to Mesa flight deals. Data was last updated October 23, 2025.

Round-trip from

$301
(United Airlines)

One-way from

$270
(American Airlines)

Popular in

August

Cheapest in

November

Average price

$684
From Columbia Regional to Mesa
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One-way flight from Columbia Regional to Mesa
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Highest demand for flights based on searches. 14% potential increase in price ($90 potential increase over avg. RT price).
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Cheapest flight prices on average. 4% potential price decrease ($25 potential savings vs. average RT price).
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Average for round-trip flights in October 2025
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Find flight deals from Columbia to Mesa

Cheapest flights from Columbia to Mesa
Explore the most affordable flight options available from Columbia to Mesa. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 23, 2025.

This United Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/226:34 pmCOU - PHX
1 stop6h 43mUnited Airlines
Mon 12/298:20 amPHX - COU
1 stop8h 05mUnited Airlines
Deal found 10/22$347
This United Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/123:05 pmCOU - PHX
1 stop8h 52mUnited Airlines
Sat 12/132:51 pmPHX - COU
1 stop4h 38mUnited Airlines
Deal found 10/22$374
This United Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/258:00 amCOU - PHX
2 stops8h 52mUnited Airlines
Mon 10/276:49 amPHX - COU
2 stops12h 30mUnited Airlines
Deal found 10/21$389
This American Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/226:05 pmCOU - PHX
1 stop5h 37mAmerican Airlines
Sun 12/2812:58 amPHX - COU
1 stop7h 41mAmerican Airlines
Deal found 10/22$470
This United Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/288:00 amCOU - PHX
1 stop7h 08mUnited Airlines
Mon 12/17:59 pmPHX - COU
1 stop23h 30mUnited Airlines
Deal found 10/22$472
This United Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/69:00 amCOU - PHX
1 stop14h 40mUnited Airlines
Mon 11/1012:55 pmPHX - COU
1 stop6h 56mUnited Airlines
Deal found 10/22$518

Cheapflights Fare Finder

 
Customize your flight search to find flights from Columbia to Mesa that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 23, 2025.
Use the filters below to find and compare flights from Columbia to Mesa that are best for you.

Fly from

Columbia

Fly to

Mesa

Route

Depart

Return

Price

ColumbiaPhoenix

COU - PHX

COUPHX

Columbia Regional

Sat 2/21

11:15 am-7:18 pm

1 stop9h 03m

Phoenix Sky Harbor Intl

Sat 2/28

12:58 pm-8:40 pm

1 stop6h 42m

$301

ColumbiaPhoenix

COU - PHX

COUPHX

Columbia Regional

Mon 12/22

6:34 pm-12:17 am

1 stop6h 43m

Phoenix Sky Harbor Intl

Mon 12/29

8:20 am-5:25 pm

1 stop8h 05m

$347

ColumbiaPhoenix

COU - PHX

COUPHX

Columbia Regional

Fri 12/12

3:05 pm-10:57 pm

1 stop8h 52m

Phoenix Sky Harbor Intl

Sat 12/13

6:35 am-5:11 pm

2 stops9h 36m

$379

ColumbiaPhoenix

COU - PHX

COUPHX

Columbia Regional

Thu 2/19

6:03 pm-11:12 pm

1 stop6h 09m

Phoenix Sky Harbor Intl

Sun 2/22

5:00 am-11:29 am

1 stop5h 29m

$445

ColumbiaPhoenix

COU - PHX

COUPHX

Columbia Regional

Mon 12/22

6:05 pm-10:42 pm

1 stop5h 37m

Phoenix Sky Harbor Intl

Sun 12/28

12:58 am-9:39 am

1 stop7h 41m

$470

ColumbiaPhoenix

COU - PHX

COUPHX

Columbia Regional

Thu 2/12

4:38 pm-11:31 pm

1 stop7h 53m

Phoenix Sky Harbor Intl

Sun 2/15

5:00 am-2:38 pm

1 stop8h 38m

$470

ColumbiaPhoenix

COU - PHX

COUPHX

Columbia Regional

Fri 11/28

8:00 am-2:08 pm

1 stop7h 08m

Phoenix Sky Harbor Intl

Mon 12/1

7:59 pm-8:29 pm

1 stop23h 30m

$472

ColumbiaPhoenix

COU - PHX

COUPHX

Columbia Regional

Sat 12/6

12:21 pm-11:52 pm

1 stop12h 31m

$270

ColumbiaPhoenix

COU - PHX

COUPHX

Columbia Regional

Sat 12/6

8:00 am-9:18 pm

2 stops14h 18m

$311

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/22

Best time to book a flight from Columbia to Mesa

Have a flexible travel schedule? Discover the best time to fly to Mesa from Columbia with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Columbia to Mesa

What is the cheapest month to book a flight from Columbia, Missouri to Mesa?

Currently, November is the cheapest month in which you can book a flight from Columbia, Missouri to Mesa (average of $317). Flying from Columbia, Missouri to Mesa in August is currently the most expensive (average of $640). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from COU to MS9?

Find hourly flight availability from Columbia to Mesa. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated October 23, 2025.

When flying from Columbia, Missouri to Mesa, the time of day you fly usually plays a role in the price. Save by searching for a flight in the evening, which can drop the price by up to 26% versus a flight in the morning.

Reviews of airlines servicing Mesa

Get insights into the airlines that provide service to Mesa. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Mesa. Reviews last updated October 23, 2025.
Get a feel of what it's like to fly with American Airlines from Columbia to Mesa by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.2
Good
11,033 reviews

Comfort

7.2

Entertainment

6.9

Crew

8.0

Boarding

7.5

Food

6.4

Overall

7.2

Reviews

1 / 20
2.0
Mediocre

Jeremy,Sep 2025

SAN - PHL

Terrible. Bad customer service and unacceptable delay on the tarmac
American Airlines
7.2
Good
11,033 reviews
American Airlines
7.2
Good
11,033 reviews

Comfort

7.2

Entertainment

6.9

Crew

8.0

Boarding

7.5

Food

6.4

Overall

7.2

Reviews

1 / 20
2.0
Mediocre

Jeremy,Sep 2025

SAN - PHL

Terrible. Bad customer service and unacceptable delay on the tarmac

Related info for your journey

Find useful and relevant information for your journey from Columbia to Mesa. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Columbia to Mesa?

    For a flight from Columbia to Mesa, you will be flying from Columbia Regional. Columbia Regional (COU) is just 11.1 mi from the center of the city. Columbia Regional is the only Columbia airport and it handles 0 outbound flights to Mesa per day. 1 airline has flights to Mesa from Columbia Regional on a regular basis.

  • How long is the flight from Columbia, Missouri to Mesa?

    For as low as $301, United Airlines can have you in Mesa from Columbia, Missouri in 9h 03m. There are 1161 mi between Columbia, Missouri and Mesa.

  • Can I find deals for flights from Columbia to Mesa that include hotel bookings?

    Yes. In addition to deals on Columbia to Mesa flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Columbia to Mesa?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Columbia to Mesa.

  • Can I find deals for business class flights from Columbia to Mesa?

    Yes. Cheapflights offers flight deals from Columbia to Mesa by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Columbia, Missouri to Mesa?

    Currently, November is the cheapest month in which you can book a flight from Columbia, Missouri to Mesa (average of $317). Flying from Columbia, Missouri to Mesa in August is currently the most expensive (average of $640). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Top airline flying from Columbia to Mesa

Discover the top airline that operate flights from Columbia to Mesa. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 23, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$370Average$514FlexibilityNo cancel feeOn-time71%

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