Medellín

$188+ Cheap flights from San Francisco (SFO) to Medellín

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/18. Fares are subject to change and may not be available on all flights or dates of travel.
SFO — MDE
Oct 14 — Oct 211
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Cheapflights Tip: The best prices from San Francisco to Medellín are usually found in August or May, booked 76 days in advance, depart on a Monday or Tuesday and return on a Thursday

Cheap flight deals from San Francisco to Medellín

Discover tips and strategies to find the most affordable flight options for your journey from San Francisco (SFO) to Medellín (CO1). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 14, 2025.

Round-trip from

$447
(Flighttix)

One-way from

$188
(Kiwi.com)

Popular in

December

Cheapest in

August

Average price

$502
From San Francisco to Medellín
One-way flight from San Francisco to Medellín
Highest demand for flights based on searches. 17% potential increase in price ($126 potential increase over avg. RT price).
Cheapest flight prices on average. 6% potential price decrease ($37 potential savings vs. average RT price).
Average for round-trip flights in September 2025

Find flight deals from San Francisco to Medellín

Cheapest flights from San Francisco to Medellín
Explore the most affordable flight options available from San Francisco to Medellín. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 14, 2025.

This Cheapflightsfares deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/1312:05 amSFO - MDE
1 stop10h 35mAvianca
Wed 10/82:10 pmMDE - SFO
1 stop10h 35mAvianca
Deal found 9/13$414
This Cheapflightsfares deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/1412:05 amSFO - MDE
2 stops14h 40mAvianca
Tue 9/302:10 pmMDE - SFO
1 stop10h 35mAvianca
Deal found 9/13$444
This Flighttix deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Flighttix is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/2511:20 pmSFO - MDE
1 stop12h 12mJetBlue
Sat 11/82:10 pmMDE - SFO
1 stop12h 21mJetBlue
Deal found 9/12$447
This Cheapflightsfares deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/1312:05 amSFO - MDE
2 stops14h 40mAvianca
Tue 9/168:52 pmMDE - SFO
2 stops17h 43mAvianca
Deal found 9/12$449
This Expedia deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/289:44 pmSFO - MDE
1 stop13h 48mJetBlue
Tue 11/42:10 pmMDE - SFO
1 stop12h 21mJetBlue
Deal found 9/13$459
This JetBlue deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/19:43 pmSFO - MDE
1 stop14h 49mJetBlue
Sun 11/162:10 pmMDE - SFO
1 stop12h 21mJetBlue
Deal found 9/12$462
This Flysmarter deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Flysmarter is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/92:30 amSFO - MDE
2 stops12h 56mAvianca
Tue 10/142:10 pmMDE - SFO
1 stop11h 45mAvianca
Deal found 9/12$466
This Avianca deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/2712:10 amSFO - MDE
1 stop10h 45mAvianca
Wed 12/32:10 pmMDE - SFO
1 stop10h 40mAvianca
Deal found 9/12$467
This Expedia deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/19:43 pmSFO - MDE
1 stop14h 49mJetBlue
Tue 11/182:10 pmMDE - SFO
1 stop12h 21mJetBlue
Deal found 9/14$469
This Expedia deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/209:00 pmSFO - MDE
2 stops15h 05mJetBlue
Fri 10/311:10 pmMDE - SFO
1 stop12h 21mJetBlue
Deal found 9/13$470

Cheapflights Fare Finder

 
Customize your flight search to find flights from San Francisco to Medellín that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 14, 2025.
Use the filters below to find and compare flights from San Francisco to Medellín that are best for you.

Fly from

San Francisco

Fly to

Medellín

Route

Depart

Return

Price

San FranciscoMedellín

SFO - MDE

SFOMDE

San Francisco

Sun 11/2

11:10 pm-12:55 pm

1 stop10h 45m

Medellín Jose Maria Cordova Intl

Sat 11/8

10:40 am-11:20 pm

2 stops15h 40m

$473

San FranciscoMedellín

SFO - MDE

SFOMDE

San Francisco

Sat 10/25

2:20 pm-6:20 am

2 stops14h 00m

Medellín Jose Maria Cordova Intl

Sat 11/8

2:10 pm-9:50 pm

1 stop10h 40m

$474

San FranciscoMedellín

SFO - MDE

SFOMDE

San Francisco

Thu 10/2

2:30 am-6:01 pm

2 stops13h 31m

Medellín Jose Maria Cordova Intl

Thu 10/9

9:18 am-10:45 pm

2 stops15h 27m

$479

San FranciscoMedellín

SFO - MDE

SFOMDE

San Francisco

Mon 10/6

1:31 am-5:00 pm

1 stop13h 29m

Medellín Jose Maria Cordova Intl

Mon 10/13

5:04 am-11:39 pm

1 stop20h 35m

$491

San FranciscoMedellín

SFO - MDE

SFOMDE

San Francisco

Fri 11/14

12:36 am-4:59 pm

1 stop13h 23m

Medellín Jose Maria Cordova Intl

Sun 11/23

9:17 am-11:17 pm

1 stop17h 00m

$491

San FranciscoMedellín

SFO - MDE

SFOMDE

San Francisco

Wed 10/29

1:36 am-4:59 pm

1 stop13h 23m

Medellín Jose Maria Cordova Intl

Sun 11/9

12:42 pm-11:17 pm

1 stop13h 35m

$491

San FranciscoMedellín

SFO - MDE

SFOMDE

San Francisco

Sun 10/26

1:36 am-10:48 pm

1 stop19h 12m

Medellín Jose Maria Cordova Intl

Sun 11/2

5:00 am-11:17 pm

1 stop21h 17m

$491

San FranciscoMedellín

SFO - MDE

SFOMDE

San Francisco

Thu 10/23

1:31 am-8:14 pm

1 stop16h 43m

Medellín Jose Maria Cordova Intl

Sun 10/26

9:17 am-11:39 pm

1 stop16h 22m

$491

San FranciscoMedellín

SFO - MDE

SFOMDE

San Francisco

Sat 12/6

4:36 pm-6:04 pm

2 stops22h 28m

$197

San FranciscoMedellín

SFO - MDE

SFOMDE

San Francisco

Tue 10/28

12:10 am-12:55 pm

1 stop10h 45m

$220

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/13

Showing 1-10 of 25 results
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Best time to book a flight from San Francisco to Medellín

Have a flexible travel schedule? Discover the best time to fly to Medellín from San Francisco with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from San Francisco to Medellín

How far ahead should I book a flight from San Francisco to Medellín?

Use this chart to determine the optimal time to book a round-trip flight from San Francisco to Medellín. Price data was last updated on September 12, 2025.

Booking 76 days in advance of your planned departure date is, on average, the best time to get cheap flights from San Francisco to Medellín. The general trend is that the closer you book to the departure date, the more expensive your flight will be.

What is the cheapest month to book a flight from San Francisco to Medellín?

Currently, January is the cheapest month in which you can book a flight from San Francisco to Medellín (average of $378). Flying from San Francisco to Medellín in December is currently the most expensive (average of $625). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SFO to MDE?

Find hourly flight availability from San Francisco to Medellín. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 14, 2025.

When flying from San Francisco to Medellín, the time of day you fly usually plays a role in the price. Save by searching for a flight in the morning, which can drop the price by up to 15% versus a flight at noon.

What is the cheapest day to fly from San Francisco to Medellín?

Use this chart to determine the cheapest time to fly round-trip from San Francisco to Medellín. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their San Francisco to Medellín flight should consider departing on Tuesday at noon when fares are most often at their lowest. Sunday at noon flights should be avoided if possible as fares are typically the most expensive at this time.

How much does it cost to fly round-trip from San Francisco to Medellín?

Reviews of airlines servicing Medellín

Get insights into the airlines that provide service to Medellín. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Medellín. Reviews last updated September 14, 2025.
Get a feel of what it's like to fly with Copa Airlines, United Airlines, and American Airlines from San Francisco to Medellín by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.

Overall

7.6

Comfort

7.4

Food

6.8

Boarding

7.8

Crew

8.1

Entertainment

6.8

Reviews

1 / 20
10.0
Excellent

Juan Pablo,Sep 2025

MEX - PTY

never better, had a very plesent trip to panama, cant say the same thing of my trip, from panama to santa cruz... it was very poor, unconftrable and boring

Overall

7.6

Comfort

7.4

Food

6.8

Boarding

7.8

Crew

8.1

Entertainment

6.8

Reviews

1 / 20
10.0
Excellent

Juan Pablo,Sep 2025

MEX - PTY

never better, had a very plesent trip to panama, cant say the same thing of my trip, from panama to santa cruz... it was very poor, unconftrable and boring

Overall

7.6

Comfort

7.4

Food

6.8

Boarding

7.8

Crew

8.1

Entertainment

6.8

Reviews

1 / 20
10.0
Excellent

Juan Pablo,Sep 2025

MEX - PTY

never better, had a very plesent trip to panama, cant say the same thing of my trip, from panama to santa cruz... it was very poor, unconftrable and boring

Overall

7.6

Comfort

7.4

Food

6.8

Boarding

7.8

Crew

8.1

Entertainment

6.8

Reviews

1 / 20
10.0
Excellent

Juan Pablo,Sep 2025

MEX - PTY

never better, had a very plesent trip to panama, cant say the same thing of my trip, from panama to santa cruz... it was very poor, unconftrable and boring

Overall

7.6

Comfort

7.4

Food

6.8

Boarding

7.8

Crew

8.1

Entertainment

6.8

Reviews

1 / 20
10.0
Excellent

Juan Pablo,Sep 2025

MEX - PTY

never better, had a very plesent trip to panama, cant say the same thing of my trip, from panama to santa cruz... it was very poor, unconftrable and boring

Overall

7.6

Comfort

7.4

Food

6.8

Boarding

7.8

Crew

8.1

Entertainment

6.8

Reviews

1 / 20
10.0
Excellent

Juan Pablo,Sep 2025

MEX - PTY

never better, had a very plesent trip to panama, cant say the same thing of my trip, from panama to santa cruz... it was very poor, unconftrable and boring

Related info for your journey

Find useful and relevant information for your journey from San Francisco to Medellín. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • What airport do you fly from for flights from San Francisco to Medellín?

    Located just 11.8 mi from the city center, San Francisco is the airport most travelers will use when flying to Medellín from San Francisco. Booking flights from San Francisco (SFO) to Medellín should be relatively easy as there are 0 daily outbound flights to Medellín from 5 different airlines.

  • How long is the flight from San Francisco to Medellín?

    There are many flights that can get you from San Francisco to Medellín in 13h 29m. Fly via Avianca or Copa Airlines to get the fastest option. The distance between San Francisco and Medellín is about 3653 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines flying from San Francisco to Medellín round-trip?

    Our cheapest airline available from San Francisco to Medellín is Avianca. Our recent data shows that you can find tickets from as low as $382 on this airline. Additional options worth looking into are Copa Airlines and JetBlue, starting at $404 and $409 round-trip. Avianca is priced at 34% lower than the current average price of a flight leaving 3 months from now.

  • Where are the most common layover locations when flying from San Francisco to Medellín?

  • What are some popular things to do or see while on a layover in Panama City?

    Panama City travelers tend to visit Panama Old Cathedral, Amador Causeway, and Panama Canal more than anywhere else. Panama Old Cathedral, Amador Causeway and Panama Canal are located about 13.2 mi, 14.7 mi, and 15.1 mi, respectively from Panama City Tocumen Intl if you are interested in checking them out. Those on a layover in Panama City in need of a rental car can book one at Panama City Tocumen Intl for about $13.

  • Where are the least popular layover locations for San Francisco to Medellín flights?

  • Can I find deals for flights from San Francisco to Medellín that include hotel bookings?

    Yes. In addition to deals on San Francisco to Medellín flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from San Francisco to Medellín?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from San Francisco to Medellín.

  • Can I find deals for business class flights from San Francisco to Medellín?

    Yes. Cheapflights offers flight deals from San Francisco to Medellín by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from San Francisco to Medellín?

    Currently, January is the cheapest month in which you can book a flight from San Francisco to Medellín (average of $378). Flying from San Francisco to Medellín in December is currently the most expensive (average of $625). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for San Francisco to Medellín

See prices for flight routes from nearby airports that may be better suited for you.

Top 5 airlines flying from San Francisco to Medellín

Discover the top 5 airlines that operate flights from San Francisco to Medellín. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 14, 2025.
AirlineCheapestAverageFlexibilityOn-time
AviancaCheapest$382Average$586FlexibilityNo cancel feeOn-time71%
Copa AirlinesCheapest$404Average$592FlexibilityNo cancel feeOn-time70%
JetBlueCheapest$409Average$665FlexibilityNo cancel feeOn-time62%
United AirlinesCheapest$444Average$602FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$463Average$750FlexibilityNo cancel feeOn-time71%

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