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$160+ Cheap flights from San Francisco (SFO) to Medellín

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/15. Fares are subject to change and may not be available on all flights or dates of travel.
SFO — MDE
Nov 28 — Dec 51
Fri 11/28
Fri 12/5
1 adult, Economy
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Cheapflights Tip: The best prices from San Francisco to Medellín are usually found in August or May, booked 76 days in advance, depart on a Monday or Tuesday and return on a Thursday

Find flight deals from San Francisco to Medellín

Cheapest flights from San Francisco to Medellín
Explore the most affordable flight options available from San Francisco to Medellín. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 29, 2025.

This Cheapflightsfares deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/272:20 pmSFO - MDE
2 stops14h 00mAvianca
Mon 11/32:10 pmMDE - SFO
1 stop10h 40mAvianca
Deal found 10/26$469
This Avianca deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/31:20 pmSFO - MDE
2 stops13h 45mAvianca
Sun 11/92:10 pmMDE - SFO
1 stop10h 40mAvianca
Deal found 10/28$474
This Cheapflightsfares deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/2712:10 amSFO - MDE
2 stops16h 45mAvianca
Wed 12/310:45 pmMDE - SFO
2 stops16h 15mAvianca
Deal found 10/27$475
This Cheapflightsfares deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/811:10 pmSFO - MDE
1 stop10h 45mAvianca
Sat 11/152:10 pmMDE - SFO
1 stop12h 10mAvianca
Deal found 10/26$476
This Avianca deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/211:10 pmSFO - MDE
2 stops12h 00mAvianca
Thu 11/138:30 amMDE - SFO
2 stops16h 20mAvianca
Deal found 10/28$480
This Cheapflightsfares deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/811:10 pmSFO - MDE
1 stop10h 45mAvianca
Wed 11/129:50 amMDE - SFO
2 stops15h 00mAvianca
Deal found 10/27$481
This FlightHub deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/211:10 pmSFO - MDE
1 stop10h 45mAvianca
Sat 11/86:25 amMDE - SFO
2 stops18h 25mAvianca
Deal found 10/28$484
This Copa Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/1412:36 amSFO - MDE
1 stop11h 09mCopa Airlines
Sun 11/239:17 amMDE - SFO
1 stop17h 00mCopa Airlines
Deal found 10/28$487
This United Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/3112:43 amSFO - MDE
1 stop18h 22mUnited Airlines
Sun 11/1610:45 amMDE - SFO
1 stop23h 50mUnited Airlines
Deal found 10/28$489
This Avianca deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/131:20 pmSFO - EOH
2 stops19h 00mAvianca
Mon 12/12:30 pmEOH - SFO
2 stops34h 20mAvianca
Deal found 10/27$1,199
This oojo deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/282:20 pmSFO - EOH
2 stops24h 25mAvianca
Wed 12/32:30 pmEOH - SFO
2 stops24h 30mAvianca
Deal found 10/28$1,212
This Avianca deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/141:20 pmSFO - EOH
2 stops42h 55mAvianca
Tue 12/210:00 amEOH - SFO
2 stops16h 20mAvianca
Deal found 10/27$1,216

Cheap flight deals from San Francisco to Medellín

Discover tips and strategies to find the most affordable flight options for your journey from San Francisco (SFO) to Medellín (CO1). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated October 29, 2025.

Round-trip from

$468
(Avianca)

One-way from

$160
(Kiwi.com)

Popular in

December

Cheapest in

August

Average price

$512
From San Francisco to Medellín
Search Deals
One-way flight from San Francisco to Medellín
Search Deals
Highest demand for flights based on searches. 17% potential increase in price ($125 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 6% potential price decrease ($36 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in October 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from San Francisco to Medellín that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 29, 2025.
Use the filters below to find and compare flights from San Francisco to Medellín that are best for you.

Fly from

San Francisco

Fly to

Medellín

Route

Depart

Return

Price

San FranciscoMedellín

SFO - MDE

SFOMDE

San Francisco

Fri 11/14

12:36 am-2:15 pm

1 stop10h 39m

Medellín Jose Maria Cordova Intl

Sun 11/23

9:17 am-11:17 pm

1 stop17h 00m

$487

San FranciscoMedellín

SFO - MDE

SFOMDE

San Francisco

Wed 12/3

12:36 am-2:15 pm

1 stop10h 39m

Medellín Jose Maria Cordova Intl

Mon 12/8

5:00 am-11:17 pm

1 stop21h 17m

$487

San FranciscoMedellín

SFO - MDE

SFOMDE

San Francisco

Mon 12/8

12:36 am-10:48 pm

1 stop19h 12m

Medellín Jose Maria Cordova Intl

Wed 12/17

6:24 am-11:17 pm

1 stop19h 53m

$487

San FranciscoMedellín

SFO - MDE

SFOMDE

San Francisco

Sat 11/1

11:59 pm-10:05 pm

1 stop20h 06m

Medellín Jose Maria Cordova Intl

Sun 11/16

10:45 am-12:12 am

1 stop16h 27m

$490

San FranciscoMedellín

SFO - MDE

SFOMDE

San Francisco

Tue 12/9

12:43 am-10:05 pm

1 stop18h 22m

Medellín Jose Maria Cordova Intl

Fri 12/19

1:15 am-6:59 pm

1 stop20h 44m

$499

San FranciscoMedellín

SFO - MDE

SFOMDE

San Francisco

Sat 11/1

12:43 am-10:05 pm

1 stop19h 22m

Medellín Jose Maria Cordova Intl

Thu 11/13

10:45 am-10:59 pm

1 stop15h 14m

$499

San FranciscoMedellín

SFO - MDE

SFOMDE

San Francisco

Tue 12/9

11:59 pm-10:05 pm

1 stop19h 06m

Medellín Jose Maria Cordova Intl

Tue 12/16

1:15 am-4:43 pm

1 stop18h 28m

$499

San FranciscoMedellín

SFO - MDE

SFOMDE

San Francisco

Fri 12/5

11:59 pm-10:05 pm

1 stop19h 06m

Medellín Jose Maria Cordova Intl

Mon 12/8

1:15 am-5:46 pm

1 stop19h 31m

$499

San FranciscoMedellín

SFO - MDE

SFOMDE

San Francisco

Mon 1/12

11:59 pm-10:05 pm

1 stop19h 06m

Medellín Jose Maria Cordova Intl

Fri 1/23

10:45 am-11:59 pm

1 stop16h 14m

$499

San FranciscoMedellín

SFO - EOH

SFOEOH

San Francisco

Wed 1/14

1:20 pm-4:00 pm

2 stops23h 40m

Medellín Enrique Olaya

Fri 1/23

10:00 am-9:50 pm

2 stops14h 50m

$1,164

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/28

Showing 1-10 of 39 results
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Best time to book a flight from San Francisco to Medellín

Have a flexible travel schedule? Discover the best time to fly to Medellín from San Francisco with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from San Francisco to Medellín

How far ahead should I book a flight from San Francisco to Medellín?

Use this chart to determine the optimal time to book a round-trip flight from San Francisco to Medellín. Price data was last updated on October 24, 2025.

Booking 76 days in advance of your planned departure date is, on average, the best time to get cheap flights from San Francisco to Medellín. The general trend is that the closer you book to the departure date, the more expensive your flight will be.

What is the cheapest month to book a flight from San Francisco to Medellín?

Currently, August is the cheapest month in which you can book a flight from San Francisco to Medellín (average of $260). Flying from San Francisco to Medellín in November is currently the most expensive (average of $465). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SFO to MDE?

Find hourly flight availability from San Francisco to Medellín. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated October 29, 2025.

When flying from San Francisco to Medellín, the time of day you fly usually plays a role in the price. Save by searching for a flight at noon, which can drop the price by up to 15% versus a flight in the evening.

What is the cheapest day to fly from San Francisco to Medellín?

Use this chart to determine the cheapest time to fly round-trip from San Francisco to Medellín. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their San Francisco to Medellín flight should consider departing on Tuesday at noon when fares are most often at their lowest. Sunday at noon flights should be avoided if possible as fares are typically the most expensive at this time.

Reviews of airlines servicing Medellín

Get insights into the airlines that provide service to Medellín. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Medellín. Reviews last updated October 29, 2025.
Get a feel of what it's like to fly with Copa Airlines, United Airlines, and American Airlines from San Francisco to Medellín by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Copa Airlines
7.6
Good
1,561 reviews

Crew

8.1

Entertainment

6.8

Food

6.8

Overall

7.6

Boarding

7.8

Comfort

7.4

Reviews

1 / 20
4.0
Okay

Juan Pablo,Sep 2025

PTY - VVI

not a good expirience, the plane was packed, the seats wear very unconftrable, coudent conect with the entratainmente service on the plane, the onboarding was in charge of a very angry lady i really had a unplesent trip
Copa Airlines
7.6
Good
1,561 reviews
Copa Airlines
7.6
Good
1,561 reviews

Crew

8.1

Entertainment

6.8

Food

6.8

Overall

7.6

Boarding

7.8

Comfort

7.4

Reviews

1 / 20
4.0
Okay

Juan Pablo,Sep 2025

PTY - VVI

not a good expirience, the plane was packed, the seats wear very unconftrable, coudent conect with the entratainmente service on the plane, the onboarding was in charge of a very angry lady i really had a unplesent trip
United Airlines
7.4
Good
9,001 reviews
Copa Airlines
7.6
Good
1,561 reviews

Crew

8.1

Entertainment

6.8

Food

6.8

Overall

7.6

Boarding

7.8

Comfort

7.4

Reviews

1 / 20
4.0
Okay

Juan Pablo,Sep 2025

PTY - VVI

not a good expirience, the plane was packed, the seats wear very unconftrable, coudent conect with the entratainmente service on the plane, the onboarding was in charge of a very angry lady i really had a unplesent trip
American Airlines
7.2
Good
11,030 reviews
Copa Airlines
7.6
Good
1,561 reviews

Crew

8.1

Entertainment

6.8

Food

6.8

Overall

7.6

Boarding

7.8

Comfort

7.4

Reviews

1 / 20
4.0
Okay

Juan Pablo,Sep 2025

PTY - VVI

not a good expirience, the plane was packed, the seats wear very unconftrable, coudent conect with the entratainmente service on the plane, the onboarding was in charge of a very angry lady i really had a unplesent trip
JetBlue
7.2
Good
2,907 reviews
Copa Airlines
7.6
Good
1,561 reviews

Crew

8.1

Entertainment

6.8

Food

6.8

Overall

7.6

Boarding

7.8

Comfort

7.4

Reviews

1 / 20
4.0
Okay

Juan Pablo,Sep 2025

PTY - VVI

not a good expirience, the plane was packed, the seats wear very unconftrable, coudent conect with the entratainmente service on the plane, the onboarding was in charge of a very angry lady i really had a unplesent trip
Avianca
6.6
Okay
2,468 reviews
Copa Airlines
7.6
Good
1,561 reviews

Crew

8.1

Entertainment

6.8

Food

6.8

Overall

7.6

Boarding

7.8

Comfort

7.4

Reviews

1 / 20
4.0
Okay

Juan Pablo,Sep 2025

PTY - VVI

not a good expirience, the plane was packed, the seats wear very unconftrable, coudent conect with the entratainmente service on the plane, the onboarding was in charge of a very angry lady i really had a unplesent trip

Related info for your journey

Find useful and relevant information for your journey from San Francisco to Medellín. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from San Francisco to Medellín?

    Located just 11.8 mi from the city center, San Francisco is the airport most travelers will use when flying to Medellín from San Francisco. Booking flights from San Francisco (SFO) to Medellín should be relatively easy as there are 0 daily outbound flights to Medellín from 5 different airlines.

  • How long is the flight from San Francisco to Medellín?

    There are many flights that can get you from San Francisco to Medellín in 10h 39m. Fly via Copa Airlines or United Airlines to get the fastest option. The distance between San Francisco and Medellín is about 3653 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines flying from San Francisco to Medellín round-trip?

    Our cheapest airline available from San Francisco to Medellín is Avianca. Our recent data shows that you can find tickets from as low as $382 on this airline. Additional options worth looking into are Copa Airlines and JetBlue, starting at $404 and $409 round-trip. Avianca is priced at 33% lower than the current average price of a flight leaving 3 months from now.

  • Where are the most common layover locations when flying from San Francisco to Medellín?

    Of the flights from San Francisco to Medellín that have layovers, most of them stop in Panama City. Panama City is followed by San Salvador in terms of the most popular layover location on flights from San Francisco to Medellín.

  • What are some popular things to do or see while on a layover in Panama City?

    Panama City travelers tend to visit Panama Old Cathedral, Amador Causeway, and Panama Canal more than anywhere else. Panama Old Cathedral, Amador Causeway and Panama Canal are located about 13.2 mi, 14.7 mi, and 15.1 mi, respectively from Panama City Tocumen Intl if you are interested in checking them out. Those on a layover in Panama City in need of a rental car can book one at Panama City Tocumen Intl for about $12.

  • Where are the least popular layover locations for San Francisco to Medellín flights?

    San Francisco to Medellín flights have a layover in Miami the least frequently. Miami is followed by Houston in terms of the least popular layover location on flights from San Francisco to Medellín.

  • Can I find deals for flights from San Francisco to Medellín that include hotel bookings?

    Yes. In addition to deals on San Francisco to Medellín flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from San Francisco to Medellín?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from San Francisco to Medellín.

  • Can I find deals for business class flights from San Francisco to Medellín?

    Yes. Cheapflights offers flight deals from San Francisco to Medellín by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from San Francisco to Medellín?

    Currently, August is the cheapest month in which you can book a flight from San Francisco to Medellín (average of $260). Flying from San Francisco to Medellín in November is currently the most expensive (average of $465). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top 5 airlines flying from San Francisco to Medellín

Discover the top 5 airlines that operate flights from San Francisco to Medellín. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 29, 2025.
AirlineCheapestAverageFlexibilityOn-time
AviancaCheapest$382Average$580FlexibilityNo cancel feeOn-time71%
Copa AirlinesCheapest$404Average$558FlexibilityNo cancel feeOn-time70%
JetBlueCheapest$409Average$680FlexibilityNo cancel feeOn-time62%
United AirlinesCheapest$429Average$597FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$463Average$728FlexibilityNo cancel feeOn-time71%

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