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Mayagüez

$1,557+ Cheap flights from South Carolina to Mayagüez (MAZ)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/10. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — MAZ
Dec 3 — Dec 101
Wed 12/3
Wed 12/10
1 adult, Economy
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Cheap flight deals from South Carolina to Mayagüez

Keep the following information in mind while searching for South Carolina to Mayagüez flight deals. Data was last updated November 3, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
1 star

Round-trip from

$1,557
(United Airlines)
Provider with most accurate pricing for Myrtle Beach Intl-Mayagüez Eugenio M De Hostos flight deals.
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Provider most trusted by Cheapflights users for Myrtle Beach Intl-Mayagüez Eugenio M De Hostos flights.
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From South Carolina to Mayagüez Eugenio M De Hostos
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Find flight deals from South Carolina to Mayagüez

Cheapest flights from South Carolina to Mayagüez
Explore the most affordable flight options available from South Carolina to Mayagüez. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 3, 2025.

This United Airlines deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/272:30 pmCAE - MAZ
2 stops48h 41mUnited Airlines
Tue 1/61:19 pmMAZ - CAE
2 stops25h 41mUnited Airlines
Deal found 11/1$2,615

Cheapflights Fare Finder

 
Customize your flight search to find flights from South Carolina to Mayagüez that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 3, 2025.
Use the filters below to find and compare flights from South Carolina to Mayagüez that are best for you.

Fly from

South Carolina

Fly to

Mayagüez

Route

Depart

Return

Price

CharlotteMayagüez

CLT - MAZ

CLTMAZ

Charlotte Douglas

Tue 3/10

7:00 am-4:11 pm

2 stops9h 11m

Mayagüez Eugenio M De Hostos

Wed 3/11

1:19 pm-11:51 pm

2 stops10h 32m

$1,557

ColumbiaMayagüez

CAE - MAZ

CAEMAZ

Columbia Metropolitan

Sat 12/27

2:30 pm-4:11 pm

2 stops48h 41m

Mayagüez Eugenio M De Hostos

Tue 1/6

1:19 pm-2:00 pm

2 stops25h 41m

$2,615

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/31

Best time to book a flight from South Carolina to Mayagüez

Have a flexible travel schedule? Discover the best time to fly to Mayagüez from South Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Carolina to Mayagüez

What is the cheapest month to book a flight from South Carolina to Mayagüez?

Currently, June is the cheapest month in which you can book a flight from South Carolina to Mayagüez (average of $151). Flying from South Carolina to Mayagüez in December is currently the most expensive (average of $321). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from South Carolina to Mayagüez. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Mayagüez from South Carolina?

    Mayagüez Eugenio M De Hostos (MAZ), located 3.7 mi from the city center, is the airport you fly into when you book flights from South Carolina to Mayagüez.

  • How long is the flight from South Carolina to Mayagüez?

    United Airlines can get you from South Carolina to Mayagüez in just under 9h 11m. Your travel time can differ by up to . South Carolina and Mayagüez are separated by a distance of 1444 mi.

  • What are the most popular routes from South Carolina to Mayagüez?

    When deciding which route to take from South Carolina to Mayagüez consider Columbia Metropolitan - Mayagüez Eugenio M De Hostos, Charlotte Douglas - Mayagüez Eugenio M De Hostos or Myrtle Beach Intl - Mayagüez Eugenio M De Hostos as they are the most popular.

  • Can I find deals for flights from South Carolina to Mayagüez that include hotel bookings?

    Yes. In addition to deals on South Carolina to Mayagüez flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from South Carolina to Mayagüez?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Carolina to Mayagüez.

  • Can I find deals for business class flights from South Carolina to Mayagüez?

    Yes. Cheapflights offers flight deals from South Carolina to Mayagüez by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from South Carolina to Mayagüez?

    Currently, June is the cheapest month in which you can book a flight from South Carolina to Mayagüez (average of $151). Flying from South Carolina to Mayagüez in December is currently the most expensive (average of $321). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Mayagüez?

Book flights to Mayagüez if you plan to visit one of these locations
Cabo Rojo
Boqueron
Rincon

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