HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
San Angelo

$429+ Cheap flights from Knoxville to San Angelo (TYS - SJT)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/24. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — SJT
nov. 26 — dic. 31
mié. 11/26
mié. 12/3
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Knoxville to San Angelo with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Knoxville to San Angelo

Discover tips and strategies to find the most affordable flight options for your journey from Knoxville (TYS) to San Angelo (SJT). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated octubre 27, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$429
(American Airlines)
Provider with most accurate pricing for Knoxville McGhee Tyson-San Angelo Mathis Field flight deals.
Search Deals
Provider most trusted by Cheapflights users for Knoxville McGhee Tyson-San Angelo Mathis Field flights.
Search Deals
From Knoxville McGhee Tyson to San Angelo Mathis Field
Search Deals

Find flight deals from Knoxville to San Angelo

Cheapest flights from Knoxville to San Angelo
Explore the most affordable flight options available from Knoxville to San Angelo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on octubre 27, 2025.

This American Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 11/245:10 amTYS - SJT
1 stop5h 38mAmerican Airlines
vie. 11/286:27 pmSJT - TYS
1 stop4h 25mAmerican Airlines
Deal found 10/26$429
This American Airlines deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 11/225:10 amTYS - SJT
1 stop5h 38mAmerican Airlines
vie. 11/286:27 pmSJT - TYS
1 stop4h 25mAmerican Airlines
Deal found 10/25$444
This American Airlines deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 12/236:20 pmTYS - SJT
1 stop6h 39mAmerican Airlines
dom. 12/286:27 pmSJT - TYS
1 stop4h 18mAmerican Airlines
Deal found 10/25$462
This American Airlines deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 11/214:27 pmTYS - SJT
1 stop6h 56mAmerican Airlines
vie. 11/286:27 pmSJT - TYS
1 stop4h 25mAmerican Airlines
Deal found 10/25$481
This American Airlines deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 12/2412:18 pmTYS - SJT
1 stop6h 39mAmerican Airlines
dom. 12/286:27 pmSJT - TYS
1 stop4h 18mAmerican Airlines
Deal found 10/25$489
This American Airlines deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 12/255:23 amTYS - SJT
1 stop5h 19mAmerican Airlines
vie. 12/265:00 amSJT - TYS
1 stop5h 28mAmerican Airlines
Deal found 10/25$499
This American Airlines deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 12/2412:18 pmTYS - SJT
1 stop6h 39mAmerican Airlines
lun. 12/295:00 amSJT - TYS
1 stop5h 28mAmerican Airlines
Deal found 10/25$531
This American Airlines deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 12/2412:18 pmTYS - SJT
1 stop6h 39mAmerican Airlines
mar. 12/306:27 pmSJT - TYS
1 stop4h 18mAmerican Airlines
Deal found 10/25$533
This American Airlines deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 12/255:23 amTYS - SJT
1 stop5h 19mAmerican Airlines
lun. 12/295:00 amSJT - TYS
1 stop5h 28mAmerican Airlines
Deal found 10/25$541
This American Airlines deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 12/256:20 pmTYS - SJT
1 stop5h 08mAmerican Airlines
mar. 12/305:00 amSJT - TYS
1 stop5h 28mAmerican Airlines
Deal found 10/25$543

Cheapflights Fare Finder

 
Customize your flight search to find flights from Knoxville to San Angelo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated octubre 27, 2025.
Use the filters below to find and compare flights from Knoxville to San Angelo that are best for you.

Fly from

Knoxville

Fly to

San Angelo

Route

Depart

Return

Price

KnoxvilleSan Angelo

TYS - SJT

TYSSJT

Knoxville McGhee Tyson

lun. 11/24

5:10 am-9:48 am

1 stop5h 38m

San Angelo Mathis Field

vie. 11/28

6:27 pm-11:52 pm

1 stop4h 25m

$429

KnoxvilleSan Angelo

TYS - SJT

TYSSJT

Knoxville McGhee Tyson

mar. 12/23

6:20 pm-11:59 pm

1 stop6h 39m

San Angelo Mathis Field

dom. 12/28

6:27 pm-11:45 pm

1 stop4h 18m

$462

KnoxvilleSan Angelo

TYS - SJT

TYSSJT

Knoxville McGhee Tyson

vie. 11/21

6:12 am-5:57 pm

2 stops12h 45m

San Angelo Mathis Field

vie. 11/28

6:27 pm-11:52 pm

1 stop4h 25m

$487

KnoxvilleSan Angelo

TYS - SJT

TYSSJT

Knoxville McGhee Tyson

mié. 12/24

12:18 pm-5:57 pm

1 stop6h 39m

San Angelo Mathis Field

sáb. 12/27

6:27 pm-11:45 pm

1 stop4h 18m

$489

KnoxvilleSan Angelo

TYS - SJT

TYSSJT

Knoxville McGhee Tyson

jue. 12/25

5:23 am-9:42 am

1 stop5h 19m

San Angelo Mathis Field

vie. 12/26

5:00 am-11:28 am

1 stop5h 28m

$499

KnoxvilleSan Angelo

TYS - SJT

TYSSJT

Knoxville McGhee Tyson

jue. 12/25

6:20 pm-10:28 pm

1 stop5h 08m

San Angelo Mathis Field

dom. 12/28

5:00 am-11:28 am

1 stop5h 28m

$499

KnoxvilleSan Angelo

TYS - SJT

TYSSJT

Knoxville McGhee Tyson

mié. 12/24

12:18 pm-5:57 pm

1 stop6h 39m

San Angelo Mathis Field

mar. 12/30

6:27 pm-11:45 pm

1 stop4h 18m

$533

KnoxvilleSan Angelo

TYS - SJT

TYSSJT

Knoxville McGhee Tyson

dom. 12/21

5:23 am-9:42 am

1 stop5h 19m

San Angelo Mathis Field

sáb. 12/27

6:27 pm-11:45 pm

1 stop4h 18m

$551

KnoxvilleSan Angelo

TYS - SJT

TYSSJT

Knoxville McGhee Tyson

mar. 12/23

6:20 pm-11:59 pm

1 stop6h 39m

San Angelo Mathis Field

vie. 12/26

5:00 am-11:28 am

1 stop5h 28m

$571

KnoxvilleSan Angelo

TYS - SJT

TYSSJT

Knoxville McGhee Tyson

mar. 12/23

6:20 pm-11:59 pm

1 stop6h 39m

San Angelo Mathis Field

sáb. 12/27

6:27 pm-11:45 pm

1 stop4h 18m

$571

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/26

Compare providers for flights from Knoxville to San Angelo

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Knoxville to San Angelo in October.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
eDreamsPrice Accuracy3 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Knoxville-San Angelo flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Knoxville-San Angelo flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Knoxville-San Angelo flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Knoxville-San Angelo flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Knoxville-San Angelo flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Knoxville to San Angelo

Have a flexible travel schedule? Discover the best time to fly to San Angelo from Knoxville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Related info for your journey

Find useful and relevant information for your journey from Knoxville to San Angelo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Knoxville to San Angelo?

    Airlines like American Airlines fly from Knoxville to San Angelo in about 5h 38m. The time it takes to get you to your destination can typically vary by up to . The distance from Knoxville to San Angelo is about 996 mi.

  • Can I find deals for flights from Knoxville to San Angelo that include hotel bookings?

    Yes. In addition to deals on Knoxville to San Angelo flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to San Angelo?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to San Angelo.

  • Can I find deals for business class flights from Knoxville to San Angelo?

    Yes. Cheapflights offers flight deals from Knoxville to San Angelo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Knoxville to San Angelo

See prices for flight routes from nearby airports that may be better suited for you.
Nashville to Dallas/Fort Worth flights
Nashville to Hobby flights
Memphis to Hobby flights
Memphis to Dallas/Fort Worth flights
Memphis to George Bush Intcntl flights
Knoxville to Hobby flights
Nashville to George Bush Intcntl flights
Knoxville to George Bush Intcntl flights
Nashville to Austin flights
Knoxville to Dallas/Fort Worth flights
Nashville to Love Field flights
Nashville to San Antonio flights
Chattanooga to Dallas/Fort Worth flights
Memphis to Love Field flights
Memphis to Austin flights
Chattanooga to Hobby flights
Knoxville to Austin flights
Chattanooga to George Bush Intcntl flights
Knoxville to San Antonio flights
Knoxville to Love Field flights
Memphis to San Antonio flights
Blountville to Dallas/Fort Worth flights
Chattanooga to Love Field flights
Blountville to Hobby flights
Chattanooga to San Antonio flights
Blountville to George Bush Intcntl flights
Memphis to El Paso flights
Chattanooga to Austin flights
Blountville to Austin flights
Blountville to Love Field flights
Nashville to El Paso flights
Nashville to Harlingen flights
Nashville to Corpus Christi flights
Memphis to McAllen flights
Nashville to Brownsville flights
Memphis to Lubbock flights
Knoxville to El Paso flights
Nashville to Amarillo flights
Nashville to McAllen flights
Nashville to Killeen flights
Nashville to Lubbock flights
Chattanooga to El Paso flights
Memphis to Laredo flights
Blountville to El Paso flights
Chattanooga to Midland flights
Nashville to Abilene flights
Nashville to Tyler flights
Nashville to College Station flights
Blountville to San Antonio flights

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.