In terms of precipitation, rainfall in San Angelo ranges from 0.7 - 2.7 inches per month. May is typically the wettest month, when rainfall can reach 2.7 in. December is typically the driest time to visit San Angelo when rainfall is around 0.7 in.

If weather is an important factor for your trip to San Angelo, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 84.2 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 46.4 F).

What is the cheapest time of day to fly from TYS to SJT?

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Knoxville to San Angelo as you normally would.

Can I find deals for flights from Knoxville to San Angelo that include hotel bookings?

Yes. In addition to deals on Knoxville to San Angelo flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Knoxville to San Angelo?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to San Angelo.

Can I find deals for business class flights from Knoxville to San Angelo?

Yes. Cheapflights offers flight deals from Knoxville to San Angelo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$458+ Flights from Knoxville to San Angelo

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Cheap flight deals from Knoxville to San Angelo

Round-trip from	$458 (American Airlines)

From Knoxville McGhee Tyson to San Angelo Mathis Field

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Cheapest flights from Knoxville to San Angelo
Explore the most affordable flight options available from Knoxville to San Angelo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 29, 2025.

Wed 9/36:24 pmTYS - SJT

1 stop5h 07mAmerican Airlines

Sat 9/67:50 amSJT - TYS

1 stop6h 51mAmerican Airlines

Deal found 7/26

$458

Best flights from Knoxville to San Angelo
Discover carefully curated flight deals from Knoxville to San Angelo that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 29, 2025.

Wed 9/36:24 pmTYS - SJT

1 stop5h 07mAmerican Airlines

Sat 9/67:50 amSJT - TYS

1 stop6h 51mAmerican Airlines

Deal found 7/26

$458

Cheapflights Fare Finder

Use the filters below to find and compare flights from Knoxville to San Angelo that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

KnoxvilleSan Angelo

TYS - SJT

TYSSJT

Knoxville McGhee Tyson

Wed 9/3

6:24 pm-10:31 pm

1 stop5h 07m

San Angelo Mathis Field

Sat 9/6

7:50 am-3:41 pm

1 stop6h 51m

$458

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/26

Best time to book a flight from Knoxville to San Angelo

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Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Reviews of airlines servicing San Angelo

Get a feel of what it's like to fly with American Airlines from Knoxville to San Angelo by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.

American Airlines

7.2

Good

10,000 reviews

Reviews

1 / 20

10.0

Excellent

Anonymous,Jan 2025

PIT - DFW

Due to gate changes,we nearly missed our flight. The gate agent reassigned our seats and would NOT give us our assigned seats,but she did honor that same request to the man who arrived after us. Her rudeness and difficulty was not appropriate.

American Airlines

7.2

Good

10,000 reviews

American Airlines

7.2

Good

10,000 reviews

Reviews

1 / 20

10.0

Excellent

Anonymous,Jan 2025

PIT - DFW

Related info for your journey

Can I find deals for flights from Knoxville to San Angelo that include hotel bookings?
Yes. In addition to deals on Knoxville to San Angelo flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Knoxville to San Angelo?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to San Angelo.
Can I find deals for business class flights from Knoxville to San Angelo?
Yes. Cheapflights offers flight deals from Knoxville to San Angelo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

Browse thousands of different options on Cheapflights for your next trip

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$458+ Cheap flights from Knoxville to San Angelo (TYS - SJT)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/3. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Knoxville to San Angelo with Cheapflights

1. Tell us where you want to go

2. Select your favorite providers

3. Compare prices and book

Cheap flight deals from Knoxville to San Angelo

Round-trip from

Find flight deals from Knoxville to San Angelo

Cheapest flights from Knoxville to San AngeloExplore the most affordable flight options available from Knoxville to San Angelo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 29, 2025.

Explore the most affordable flight options available from Knoxville to San Angelo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 29, 2025.

Cheapflights Fare Finder

Use the filters below to find and compare flights from Knoxville to San Angelo that are best for you.

Best time to book a flight from Knoxville to San Angelo

Have a flexible travel schedule? Discover the best time to fly to San Angelo from Knoxville with our price prediction graph.

Reviews of airlines servicing San Angelo

Get a feel of what it's like to fly with American Airlines from Knoxville to San Angelo by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from Knoxville to San Angelo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

Can I find deals for flights from Knoxville to San Angelo that include hotel bookings?

How can I find direct flights from Knoxville to San Angelo?

Can I find deals for business class flights from Knoxville to San Angelo?

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Knoxville to San Angelo

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100% Free

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Travel Smart

Cheapest flights from Knoxville to San Angelo
Explore the most affordable flight options available from Knoxville to San Angelo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 29, 2025.