$153+ Cheap flights from San Antonio to Louisville (SAT - SDF)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/26. Fares are subject to change and may not be available on all flights or dates of travel.
SAT — SDF
May 27 — Jun 31
Round-trip
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from San Antonio to Louisville with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from San Antonio to Louisville
Cheapest
Best
Last-minute
One-way
Cheapest flights from San Antonio to LouisvilleExplore the most affordable flight options available from San Antonio to Louisville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 27, 2026.
Explore the most affordable flight options available from San Antonio to Louisville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 27, 2026.
This Delta deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/232:00 pm
SAT
- SDF
1 stop7h 50m
Delta
Mon 9/287:30 pm
SDF
- SAT
1 stop5h 45m
Delta
Deal found 4/23![Delta logo]()
$290
This Kiwi.com deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/285:26 pm
SAT
- SDF
1 stop15h 02m
Multiple Airlines
Sat 5/308:06 pm
SDF
- SAT
1 stop14h 04m
Multiple Airlines
Deal found 4/23![Multiple Airlines logo]()
$291
This CheapOair deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/105:26 pm
SAT
- SDF
1 stop15h 02m
Spirit Airlines
Sun 5/1710:33 am
SDF
- SAT
1 stop6h 43m
Spirit Airlines
Deal found 4/22![Spirit Airlines logo]()
$295
This United Airlines deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/195:34 pm
SAT
- SDF
1 stop5h 22m
United Airlines
Wed 5/209:15 am
SDF
- SAT
1 stop7h 24m
United Airlines
Deal found 4/27![United Airlines logo]()
$302
This Southwest deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/166:50 am
SAT
- SDF
1 stop4h 20m
Southwest
Tue 9/2212:10 pm
SDF
- SAT
1 stop6h 15m
Southwest
Deal found 4/26![Southwest logo]()
$307
This Southwest deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/1912:30 pm
SAT
- SDF
2 stops7h 05m
Southwest
Wed 5/207:00 am
SDF
- SAT
1 stop4h 40m
Southwest
Deal found 4/27![Southwest logo]()
$312
This CheapOair deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/215:26 pm
SAT
- SDF
1 stop15h 02m
Spirit Airlines
Thu 5/2810:33 am
SDF
- SAT
1 stop6h 43m
Spirit Airlines
Deal found 4/27![Spirit Airlines logo]()
$324
This Southwest deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/284:25 pm
SAT
- SDF
1 stop4h 20m
Southwest
Sat 5/308:40 am
SDF
- SAT
2 stops8h 05m
Southwest
Deal found 4/23![Southwest logo]()
$332
This Southwest deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/224:30 pm
SAT
- SDF
1 stop6h 15m
Southwest
Tue 5/261:35 pm
SDF
- SAT
1 stop5h 25m
Southwest
Deal found 4/27![Southwest logo]()
$367
Best flights from San Antonio to LouisvilleDiscover carefully curated flight deals from San Antonio to Louisville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 27, 2026.
Discover carefully curated flight deals from San Antonio to Louisville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 27, 2026.
This Southwest deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/1912:30 pm
SAT
- SDF
2 stops7h 05m
Southwest
Wed 5/207:00 am
SDF
- SAT
1 stop4h 40m
Southwest
Deal found 4/27![Southwest logo]()
$312
This CheapOair deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/215:26 pm
SAT
- SDF
1 stop15h 02m
Spirit Airlines
Thu 5/2810:33 am
SDF
- SAT
1 stop6h 43m
Spirit Airlines
Deal found 4/24![Spirit Airlines logo]()
$324
This United Airlines deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/192:25 pm
SAT
- SDF
1 stop4h 35m
United Airlines
Wed 5/209:00 am
SDF
- SAT
1 stop8h 57m
United Airlines
Deal found 4/22![United Airlines logo]()
$373
This Southwest deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/222:10 pm
SAT
- SDF
1 stop9h 05m
Southwest
Fri 5/298:10 pm
SDF
- SAT
1 stop5h 20m
Southwest
Deal found 4/22![Southwest logo]()
$389
This Southwest deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/189:50 am
SAT
- SDF
1 stop7h 20m
Southwest
Sat 8/12:55 pm
SDF
- SAT
1 stop7h 55m
Southwest
Deal found 4/22![Southwest logo]()
$407
Last-minute flights from San Antonio to LouisvilleDiscover last-minute flight deals from San Antonio to Louisville. Data last updated April 27, 2026 and is based on user searches.
Discover last-minute flight deals from San Antonio to Louisville. Data last updated April 27, 2026 and is based on user searches.
This CheapOair deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/105:26 pm
SAT
- SDF
1 stop15h 02m
Spirit Airlines
Sun 5/1710:33 am
SDF
- SAT
1 stop6h 43m
Spirit Airlines
Deal found 4/22![Spirit Airlines logo]()
$295
This United Airlines deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/195:34 pm
SAT
- SDF
1 stop5h 22m
United Airlines
Wed 5/209:15 am
SDF
- SAT
1 stop7h 24m
United Airlines
Deal found 4/27![United Airlines logo]()
$302
This Southwest deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/1912:30 pm
SAT
- SDF
2 stops7h 05m
Southwest
Wed 5/207:00 am
SDF
- SAT
1 stop4h 40m
Southwest
Deal found 4/27![Southwest logo]()
$312
This CheapOair deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/215:26 pm
SAT
- SDF
1 stop15h 02m
Spirit Airlines
Thu 5/2810:33 am
SDF
- SAT
1 stop6h 43m
Spirit Airlines
Deal found 4/27![Spirit Airlines logo]()
$324
This Southwest deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/224:30 pm
SAT
- SDF
1 stop6h 15m
Southwest
Tue 5/261:35 pm
SDF
- SAT
1 stop5h 25m
Southwest
Deal found 4/27![Southwest logo]()
$367
This Kiwi.com deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/285:26 pm
SAT
- SDF
1 stop15h 02m
Multiple Airlines
Sat 5/308:06 pm
SDF
- SAT
1 stop14h 04m
Multiple Airlines
Deal found 4/23![Multiple Airlines logo]()
$291
This Southwest deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/284:25 pm
SAT
- SDF
1 stop4h 20m
Southwest
Sat 5/308:40 am
SDF
- SAT
2 stops8h 05m
Southwest
Deal found 4/23![Southwest logo]()
$332
One-way flights from San Antonio to LouisvilleSearch for one-way flight options from San Antonio to Louisville. Find affordable one-way fares based on user searches. Data last updated April 27, 2026.
Search for one-way flight options from San Antonio to Louisville. Find affordable one-way fares based on user searches. Data last updated April 27, 2026.
This Kiwi.com deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/2611:30 am
SAT
- SDF
2 stops20h 06m
Breeze Airways
Deal found 4/24![Breeze Airways logo]()
$153
This Delta deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/52:35 pm
SAT
- SDF
1 stop8h 17m
Delta
Deal found 4/23![Delta logo]()
$186
This Kiwi.com deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/511:30 am
SAT
- SDF
3 stops53h 45m
Multiple Airlines
Deal found 4/23![Multiple Airlines logo]()
$199
This American Airlines deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/265:52 pm
SAT
- SDF
1 stop5h 36m
American Airlines
Deal found 4/24![American Airlines logo]()
$204
This Kiwi.com deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/67:54 pm
SAT
- SDF
3 stops46h 04m
Multiple Airlines
Deal found 4/25![Multiple Airlines logo]()
$260
This Kiwi.com deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/264:22 pm
SAT
- SDF
3 stops41h 02m
Multiple Airlines
Deal found 4/24![Multiple Airlines logo]()
$266
This American Airlines deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/64:28 pm
SAT
- SDF
1 stop4h 13m
American Airlines
Deal found 4/25![American Airlines logo]()
$389
This United Airlines deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/305:49 pm
SAT
- SDF
1 stop5h 07m
United Airlines
Deal found 4/25![United Airlines logo]()
$699
Find flight deals from San Antonio to Louisville
Discover tips and strategies to find the most affordable flight options for your journey from San Antonio (SAT) to Louisville (SDF). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated April 27, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $290 (Delta) |
One-way from | $153 (Kiwi.com) |
Popular in | April |
Cheapest in | August |
Average price | $456 |
Cheapflights Fare Finder
Customize your flight search to find flights from San Antonio to Louisville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 27, 2026.
Use the filters below to find and compare flights from San Antonio to Louisville that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Quickest round-trip
San AntonioLouisville
SAT - SDF
SATSDF
San Antonio
Tue 5/19
12:30 pm-8:35 pm
2 stops7h 05m
Louisville Intl
Wed 5/20
7:00 am-10:40 am
1 stop4h 40m
$312
San AntonioLouisville
SAT - SDF
SATSDF
San Antonio
Thu 5/21
5:26 pm-9:28 am
1 stop15h 02m
Louisville Intl
Thu 5/28
10:33 am-4:16 pm
1 stop6h 43m
$324
San AntonioLouisville
SAT - SDF
SATSDF
San Antonio
Tue 5/19
2:25 pm-8:00 pm
1 stop4h 35m
Louisville Intl
Wed 5/20
9:00 am-4:57 pm
1 stop8h 57m
$373
San AntonioLouisville
SAT - SDF
SATSDF
San Antonio
Fri 5/22
2:10 pm-12:15 am
1 stop9h 05m
Louisville Intl
Fri 5/29
8:10 pm-12:30 am
1 stop5h 20m
$389
San AntonioLouisville
SAT - SDF
SATSDF
San Antonio
Sat 7/18
9:50 am-6:10 pm
1 stop7h 20m
Louisville Intl
Sat 8/1
2:55 pm-9:50 pm
1 stop7h 55m
$407
Cheapest one-way
San AntonioLouisville
SAT - SDF
SATSDF
San Antonio
Fri 6/5
2:35 pm-11:52 pm
1 stop8h 17m
$186
San AntonioLouisville
SAT - SDF
SATSDF
San Antonio
Fri 6/5
11:30 am-6:15 pm
3 stops53h 45m
$199
San AntonioLouisville
SAT - SDF
SATSDF
San Antonio
Fri 6/26
5:52 pm-12:28 am
1 stop5h 36m
$204
San AntonioLouisville
SAT - SDF
SATSDF
San Antonio
Wed 5/6
7:54 pm-6:58 pm
3 stops46h 04m
$260
San AntonioLouisville
SAT - SDF
SATSDF
San Antonio
Fri 6/26
4:22 pm-10:24 am
3 stops41h 02m
$266
Showing 1-10 of 11 resultsSorted by cheapest first
Compare providers for flights from San Antonio to Louisville
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from San Antonio to Louisville in April.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy- | Trust Score*1 star |
- Most accurate provider: When it comes to deals on San Antonio-Louisville flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on San Antonio-Louisville flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from San Antonio-Louisville flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on San Antonio-Louisville flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for San Antonio-Louisville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from San Antonio to Louisville
Have a flexible travel schedule? Discover the best time to fly to Louisville from San Antonio with our price prediction graph.
SAT-SDF
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from San Antonio to Louisville
Prices
More
What is the cheapest month to book a flight from San Antonio to Louisville?
Currently, August is the cheapest month in which you can book a flight from San Antonio to Louisville (average of $306). Flying from San Antonio to Louisville in April is currently the most expensive (average of $456). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from San Antonio to Louisville?
What’s the top layover airport for flights from San Antonio to Louisville?
Share of 1-stop round-trip flights from San Antonio to Louisville chosen by Cheapflights users in the past 12 months, using the same layover each way.
Dallas (DFW) – chosen by Cheapflights users on 92% of 1-stop itineraries from San Antonio to Louisville on Cheapflights.
What’s the cheapest layover airport for flights from San Antonio to Louisville?
Average round-trip fare for 1-stop flights from San Antonio to Louisville, chosen by Cheapflights users in the past 12 months, with the same layover each way.
Fort Lauderdale (FLL) is the most affordable 1-stop option, with an average round-trip price of $307.
What’s the fastest layover option from San Antonio to Louisville?
Shortest average travel time for 1-stop one-way flights from San Antonio to Louisville, based on itineraries clicked by Cheapflights users over the past 12 months, grouped by layover airport.
Flights via Dallas (DFW) have the shortest average one-way travel time for 1-stop routes: 4h 16m.
Which airport typically offers the quickest layover for flights from San Antonio to Louisville?
Average layover duration for 1-stop one-way flights from San Antonio to Louisville, chosen by Cheapflights users in the last 12 months, grouped by stopover airport.
Flights via Dallas (DFW) offer the fastest connection on this route, with an average layover time of 1h 01m.
Reviews of airlines servicing Louisville
Get insights into the airlines that provide service to Louisville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Louisville. Reviews last updated April 27, 2026.
Read through reviews of airlines operating flights from San Antonio to Louisville, such as Southwest,Delta, andUnited Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Comfort
8.0
Overall
8.0
Entertainment
7.5
Food
7.0
Boarding
8.1
Crew
8.6
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Comfort
8.0
Overall
8.0
Entertainment
7.5
Food
7.0
Boarding
8.1
Crew
8.6
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Comfort
8.0
Overall
8.0
Entertainment
7.5
Food
7.0
Boarding
8.1
Crew
8.6
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Comfort
8.0
Overall
8.0
Entertainment
7.5
Food
7.0
Boarding
8.1
Crew
8.6
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Comfort
8.0
Overall
8.0
Entertainment
7.5
Food
7.0
Boarding
8.1
Crew
8.6
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Related info for your journey
Find useful and relevant information for your journey from San Antonio to Louisville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Louisville?
Book flights to Louisville if you plan to visit one of these locationsShepherdsville
Elizabethtown
Corydon
Jeffersonville
Bardstown
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Complete your trip
Flights by cabin class
Louisville flight routes
Other flight options
Other flights from San Antonio
Popular flights
Alternative routes for San Antonio to Louisville
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Louisville by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from San Antonio to Louisville by cabin class
Find flights from San Antonio to Louisville, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Other flights to Louisville
Explore flights to Louisville departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on April 27, 2026.
San Antonio and Louisville flights
Browse other San Antonio and Louisville flight options. Last updated on April 27, 2026.
Other flights from San Antonio
Browse through other flights departing from San Antonio. Flights are based on user searches made on Cheapflights and were last updated on April 27, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 4 airlines flying from San Antonio to Louisville
Discover the top 4 airlines that operate flights from San Antonio to Louisville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 27, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$123 | Average$344 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$236 | Average$386 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$270 | Average$389 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$276 | Average$363 | FlexibilityNo cancel fee | On-time71% |