$273+ Cheap flights from McAllen to Louisville (MFE - SDF)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/6. Fares are subject to change and may not be available on all flights or dates of travel.
MFE — SDF
Oct 18 — Oct 251
Round-trip
1 adult, Economy
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Find cheap flights from McAllen to Louisville with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from McAllen to Louisville
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Best
Last-minute
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Cheapest flights from McAllen to LouisvilleExplore the most affordable flight options available from McAllen to Louisville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 18, 2026.
Explore the most affordable flight options available from McAllen to Louisville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 18, 2026.
This Delta deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/2112:46 pm -
2 stops10h 13m
Sat 10/2411:06 am -
2 stops8h 17m
Deal found 9/16![Delta logo]()
$331
This American Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/214:37 pm -
1 stop5h 50m
Sat 10/246:00 am -
1 stop5h 32m
Deal found 9/16![American Airlines logo]()
$371
This American Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/214:37 pm -
1 stop5h 50m
Sun 10/256:00 am -
1 stop5h 32m
Deal found 9/16![American Airlines logo]()
$385
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/177:00 am -
1 stop4h 51m
Sat 9/196:00 am -
1 stop5h 35m
Deal found 9/15![American Airlines logo]()
$465
This United Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/172:08 pm -
1 stop4h 47m
Sat 9/197:10 am -
2 stops9h 49m
Deal found 9/15![United Airlines logo]()
$470
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/64:21 pm -
1 stop6h 13m
Sun 11/86:54 pm -
1 stop6h 21m
Deal found 9/14![American Airlines logo]()
$475
This American Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/25:44 am -
1 stop6h 07m
Tue 10/65:49 pm -
1 stop7h 23m
Deal found 9/17![American Airlines logo]()
$486
This United Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/29:40 am -
2 stops13h 01m
Tue 10/63:37 pm -
1 stop7h 21m
Deal found 9/17![United Airlines logo]()
$494
Best flights from McAllen to LouisvilleDiscover carefully curated flight deals from McAllen to Louisville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 18, 2026.
Discover carefully curated flight deals from McAllen to Louisville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 18, 2026.
This Delta deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/2112:46 pm -
2 stops10h 13m
Sat 10/2411:06 am -
2 stops8h 17m
Deal found 9/16![Delta logo]()
$331
This United Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/2311:55 am -
1 stop6h 40m
Wed 1/279:32 am -
1 stop7h 41m
Deal found 9/16![United Airlines logo]()
$411
Last-minute flights from McAllen to LouisvilleDiscover last-minute flight deals from McAllen to Louisville. Data last updated September 18, 2026 and is based on user searches.
Discover last-minute flight deals from McAllen to Louisville. Data last updated September 18, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/25:44 am -
1 stop6h 07m
Tue 10/65:49 pm -
1 stop7h 23m
Deal found 9/17![American Airlines logo]()
$486
This United Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/29:40 am -
2 stops13h 01m
Tue 10/63:37 pm -
1 stop7h 21m
Deal found 9/17![United Airlines logo]()
$494
This Delta deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/2112:46 pm -
2 stops10h 13m
Sat 10/2411:06 am -
2 stops8h 17m
Deal found 9/16![Delta logo]()
$331
This American Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/214:37 pm -
1 stop5h 50m
Sat 10/246:00 am -
1 stop5h 32m
Deal found 9/16![American Airlines logo]()
$371
This American Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/214:37 pm -
1 stop5h 50m
Sun 10/256:00 am -
1 stop5h 32m
Deal found 9/16![American Airlines logo]()
$385
This United Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/217:00 am -
2 stops12h 13m
Sun 10/255:10 am -
2 stops9h 19m
Deal found 9/16![United Airlines logo]()
$574
This Delta deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/2112:46 pm -
2 stops10h 13m
Sun 10/256:00 am -
2 stops7h 06m
Deal found 9/16![Delta logo]()
$625
One-way flights from McAllen to LouisvilleSearch for one-way flight options from McAllen to Louisville. Find affordable one-way fares based on user searches. Data last updated September 18, 2026.
Search for one-way flight options from McAllen to Louisville. Find affordable one-way fares based on user searches. Data last updated September 18, 2026.
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/64:21 pm -
1 stop6h 13m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/14![American Airlines logo]()
$273
This Delta deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/612:46 pm -
2 stops9h 05m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/14![Delta logo]()
$278
This Kiwi.com deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/610:12 pm -
3 stops45h 17m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/14![Multiple Airlines logo]()
$306
This American Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/2511:21 am -
1 stop4h 58m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/17![American Airlines logo]()
$424
This United Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/259:40 am -
2 stops13h 01m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/17![United Airlines logo]()
$485
This Kiwi.com deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/258:39 pm -
3 stops46h 50m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/17![Multiple Airlines logo]()
$548
Find flight deals from McAllen to Louisville
Discover tips and strategies to find the most affordable flight options for your journey from McAllen (MFE) to Louisville (SDF). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 18, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $331 (Delta) |
One-way from | $273 (American Airlines) |
Cheapflights Fare Finder
Customize your flight search to find flights from McAllen to Louisville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 18, 2026.
Use the filters below to find and compare flights from McAllen to Louisville that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
McAllenLouisville
MFE McAllen Miller Intl - SDF Louisville Intl
MFESDF
McAllen Miller Intl
Fri 11/6
4:21 pm-11:34 pm
1 stop6h 13m
Louisville Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$273
McAllenLouisville
MFE McAllen Miller Intl - SDF Louisville Intl
MFESDF
McAllen Miller Intl
Fri 11/6
12:46 pm-10:51 pm
2 stops9h 05m
Louisville Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$278
McAllenLouisville
MFE McAllen Miller Intl - SDF Louisville Intl
MFESDF
McAllen Miller Intl
Fri 11/6
10:12 pm-8:29 pm
3 stops45h 17m
Louisville Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$306
McAllenLouisville
MFE McAllen Miller Intl - SDF Louisville Intl
MFESDF
McAllen Miller Intl
Wed 10/21
12:46 pm-11:59 pm
2 stops10h 13m
Louisville Intl
Sat 10/24
11:06 am-6:23 pm
2 stops8h 17m
$331
McAllenLouisville
MFE McAllen Miller Intl - SDF Louisville Intl
MFESDF
McAllen Miller Intl
Sat 1/23
11:55 am-7:35 pm
1 stop6h 40m
Louisville Intl
Wed 1/27
9:32 am-4:13 pm
1 stop7h 41m
$411
Quickest round-trip
McAllenLouisville
MFE McAllen Miller Intl - SDF Louisville Intl
MFESDF
McAllen Miller Intl
Fri 9/25
11:21 am-5:19 pm
1 stop4h 58m
Louisville Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$424
McAllenLouisville
MFE McAllen Miller Intl - SDF Louisville Intl
MFESDF
McAllen Miller Intl
Fri 9/25
9:40 am-11:41 pm
2 stops13h 01m
Louisville Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$485
McAllenLouisville
MFE McAllen Miller Intl - SDF Louisville Intl
MFESDF
McAllen Miller Intl
Fri 9/25
8:39 pm-8:29 pm
3 stops46h 50m
Louisville Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$548
Sorted by cheapest first
Compare providers for flights from McAllen to Louisville
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from McAllen to Louisville in September.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on McAllen-Louisville flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on McAllen-Louisville flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from McAllen-Louisville flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on McAllen-Louisville flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for McAllen-Louisville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from McAllen to Louisville
Have a flexible travel schedule? Discover the best time to fly to Louisville from McAllen with our price prediction graph.
MFE-SDF
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Related info for your journey
Find useful and relevant information for your journey from McAllen to Louisville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Louisville?
Book flights to Louisville if you plan to visit one of these locationsShepherdsville
Elizabethtown
Jeffersonville
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