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$121+ Cheap flights from Mesa, AZ to Louisville (SDF)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/25. Fares are subject to change and may not be available on all flights or dates of travel.
PHX — SDF
Feb 28 — Mar 71
Sat 2/28
Sat 3/7
1 adult, Economy
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Cheapflights Tip: The best prices from Mesa to Louisville Intl are usually found in November or August, booked 79 days in advance, depart on a Monday or Saturday and return on a Wednesday

Cheap flight deals from Mesa to Louisville

Cheapest flights from Mesa to Louisville
Explore the most affordable flight options available from Mesa to Louisville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 29, 2026.

This Kiwi.com deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/2411:59 pm
PHX
-
SDF
1 stop10h 22m
Multiple Airlines
Tue 3/33:33 pm
SDF
-
PHX
2 stops29h 21m
Multiple Airlines
Deal found 1/26$268
This Kiwi.com deal was found by Cheapflights users on 1/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/2411:59 pm
PHX
-
SDF
1 stop10h 22m
Multiple Airlines
Thu 2/263:33 pm
SDF
-
PHX
2 stops19h 17m
Multiple Airlines
Deal found 1/29$297
This Kiwi.com deal was found by Cheapflights users on 1/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/2411:59 pm
PHX
-
SDF
1 stop10h 22m
Multiple Airlines
Fri 2/271:19 pm
SDF
-
PHX
2 stops36h 25m
Multiple Airlines
Deal found 1/29$309
This Kiwi.com deal was found by Cheapflights users on 1/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/2411:59 pm
PHX
-
SDF
1 stop10h 22m
Multiple Airlines
Sat 2/2812:00 pm
SDF
-
PHX
2 stops13h 44m
Multiple Airlines
Deal found 1/29$316
This Kiwi.com deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/2611:59 pm
PHX
-
SDF
1 stop10h 22m
Multiple Airlines
Sun 3/13:33 pm
SDF
-
PHX
2 stops19h 37m
Multiple Airlines
Deal found 1/27$320
This Kiwi.com deal was found by Cheapflights users on 1/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/2211:59 pm
PHX
-
SDF
1 stop10h 22m
Multiple Airlines
Tue 2/243:33 pm
SDF
-
PHX
2 stops24h 22m
Multiple Airlines
Deal found 1/29$345
This Kiwi.com deal was found by Cheapflights users on 1/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/2611:59 pm
PHX
-
SDF
1 stop10h 22m
Multiple Airlines
Sat 2/2812:00 pm
SDF
-
PHX
2 stops13h 44m
Multiple Airlines
Deal found 1/29$349
This Delta deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/86:10 am
PHX
-
SDF
1 stop8h 05m
Delta
Tue 4/144:42 pm
SDF
-
PHX
1 stop6h 08m
Delta
Deal found 1/28$357
This United Airlines deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/86:00 am
PHX
-
SDF
2 stops7h 41m
United Airlines
Thu 4/167:20 am
SDF
-
PHX
1 stop8h 51m
United Airlines
Deal found 1/28$362
This Kiwi.com deal was found by Cheapflights users on 1/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/2211:59 pm
PHX
-
SDF
1 stop10h 22m
Multiple Airlines
Thu 2/263:33 pm
SDF
-
PHX
2 stops19h 17m
Multiple Airlines
Deal found 1/29$364
This Kiwi.com deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/1012:59 am
PHX
-
SDF
1 stop8h 22m
Multiple Airlines
Sun 3/153:33 pm
SDF
-
PHX
2 stops19h 04m
Multiple Airlines
Deal found 1/27$372

Find flight deals from Mesa to Louisville

Keep the following information in mind while searching for Mesa to Louisville flight deals. Data was last updated January 29, 2026.

Round-trip from

$268
(Kiwi.com)

One-way from

$121
(Kiwi.com)

Popular in

February

Cheapest in

November

Average price

$451
From Mesa to Louisville Intl
Search Deals
One-way flight from Mesa to Louisville Intl
Search Deals
Highest demand for flights based on searches. 4% potential increase in price ($22 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 1% potential price decrease ($7 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in January 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Mesa to Louisville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 29, 2026.
Use the filters below to find and compare flights from Mesa to Louisville that are best for you.

Fly from

Mesa

Fly to

Louisville

Route

Depart

Return

Price

PhoenixLouisville

PHX - SDF

PHXSDF

Phoenix Sky Harbor Intl

Tue 2/24

11:59 pm-12:21 pm

1 stop10h 22m

Louisville Intl

Tue 3/3

3:33 pm-6:54 pm

2 stops29h 21m

$268

PhoenixLouisville

PHX - SDF

PHXSDF

Phoenix Sky Harbor Intl

Thu 2/26

11:59 pm-12:21 pm

1 stop10h 22m

Louisville Intl

Sun 3/1

3:33 pm-9:10 am

2 stops19h 37m

$320

PhoenixLouisville

PHX - SDF

PHXSDF

Phoenix Sky Harbor Intl

Wed 4/8

6:10 am-5:15 pm

1 stop8h 05m

Louisville Intl

Wed 4/15

5:48 pm-9:11 pm

1 stop6h 23m

$357

PhoenixLouisville

PHX - SDF

PHXSDF

Phoenix Sky Harbor Intl

Wed 4/8

7:00 am-4:41 pm

1 stop6h 41m

Louisville Intl

Thu 4/16

7:20 am-1:11 pm

1 stop8h 51m

$357

PhoenixLouisville

PHX - SDF

PHXSDF

Phoenix Sky Harbor Intl

Tue 4/7

11:10 pm-8:38 am

1 stop6h 28m

Louisville Intl

Sat 4/11

7:37 am-11:24 am

1 stop6h 47m

$357

PhoenixLouisville

PHX - SDF

PHXSDF

Phoenix Sky Harbor Intl

Sun 4/12

11:55 pm-8:52 am

1 stop5h 57m

Louisville Intl

Wed 4/15

4:42 pm-7:50 pm

1 stop6h 08m

$357

PhoenixLouisville

PHX - SDF

PHXSDF

Phoenix Sky Harbor Intl

Tue 4/28

10:35 pm-10:24 am

1 stop8h 49m

Louisville Intl

Thu 5/7

7:30 pm-11:02 pm

1 stop6h 32m

$357

PhoenixLouisville

PHX - SDF

PHXSDF

Phoenix Sky Harbor Intl

Mon 4/13

10:35 pm-8:52 am

1 stop7h 17m

Louisville Intl

Tue 4/14

1:00 pm-7:11 pm

1 stop9h 11m

$357

PhoenixLouisville

PHX - SDF

PHXSDF

Phoenix Sky Harbor Intl

Sat 4/11

11:59 pm-11:51 am

1 stop8h 52m

Louisville Intl

Mon 4/13

3:17 pm-9:11 pm

1 stop8h 54m

$357

PhoenixLouisville

PHX - SDF

PHXSDF

Phoenix Sky Harbor Intl

Sat 4/18

11:55 pm-10:24 am

1 stop7h 29m

Louisville Intl

Sun 4/19

3:17 pm-7:11 pm

1 stop6h 54m

$357

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/28

Showing 1-10 of 24 results
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Best time to book a flight from Mesa to Louisville

Have a flexible travel schedule? Discover the best time to fly to Louisville from Mesa with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Mesa to Louisville

How far ahead should I book a flight from Mesa to Louisville?

Use this chart to determine the optimal time to book a round-trip flight from Mesa to Louisville. Price data was last updated on January 23, 2026.

To ensure you get the cheapest price possible for a flight from Mesa to Louisville, you should look to book at least 79 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.

What is the cheapest month to book a flight from Mesa to Louisville?

Currently, February is the cheapest month in which you can book a flight from Mesa to Louisville (average of $69). Flying from Mesa to Louisville in June is currently the most expensive (average of $177). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MS9 to SDF?

Find hourly flight availability from Mesa to Louisville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated January 29, 2026.

It’s optimal to fly from Mesa to Louisville in the evening. By choosing this option you can save up to 36% on the cost of your flight, compared to a flight in the afternoon.

Reviews of airlines servicing Louisville

Get insights into the airlines that provide service to Louisville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Louisville. Reviews last updated January 29, 2026.
Peruse reviews from past customers who have flown with Southwest, Delta, and United Airlines from Mesa to Louisville to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,267 reviews

Overall

8.0

Crew

8.6

Comfort

8.0

Boarding

8.1

Entertainment

7.5

Food

7.0

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
Southwest
8.0
Very good
4,267 reviews
Southwest
8.0
Very good
4,267 reviews

Overall

8.0

Crew

8.6

Comfort

8.0

Boarding

8.1

Entertainment

7.5

Food

7.0

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
Delta
7.9
Good
8,128 reviews
Southwest
8.0
Very good
4,267 reviews

Overall

8.0

Crew

8.6

Comfort

8.0

Boarding

8.1

Entertainment

7.5

Food

7.0

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
United Airlines
7.4
Good
9,215 reviews
Southwest
8.0
Very good
4,267 reviews

Overall

8.0

Crew

8.6

Comfort

8.0

Boarding

8.1

Entertainment

7.5

Food

7.0

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
American Airlines
7.2
Good
11,205 reviews
Southwest
8.0
Very good
4,267 reviews

Overall

8.0

Crew

8.6

Comfort

8.0

Boarding

8.1

Entertainment

7.5

Food

7.0

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

Related info for your journey

Find useful and relevant information for your journey from Mesa to Louisville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Louisville from Mesa?

    Located just 5.3 mi from the city center, Louisville Intl is the airport most travelers will use when flying to Louisville from Mesa. Booking flights from Mesa to Louisville Intl (SDF) should be relatively easy as there are 0 daily inbound flights from Mesa from 4 different airlines.

  • How long is the flight from Mesa to Louisville?

    Departing from Mesa to Louisville will take you 6h 41m. The distance from Mesa to Louisville is about 1501 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines to fly from Mesa to Louisville one-way?

    The cheapest airlines for a one-way flight from Mesa to Louisville are American Airlines ($109), United Airlines ($177), and Southwest ($198).

  • What are the cheapest flights from Mesa to Louisville?

    The cheapest flight price from Mesa to Louisville is $176. On average you can expect to pay $459. The most popular route, (Phoenix Sky Harbor Intl - Louisville Intl), can usually be booked for $345.

  • Can I find deals for flights from Mesa to Louisville that include hotel bookings?

    Yes. In addition to deals on Mesa to Louisville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Mesa to Louisville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Mesa to Louisville.

  • Can I find deals for business class flights from Mesa to Louisville?

    Yes. Cheapflights offers flight deals from Mesa to Louisville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Mesa to Louisville?

    Currently, February is the cheapest month in which you can book a flight from Mesa to Louisville (average of $69). Flying from Mesa to Louisville in June is currently the most expensive (average of $177). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Louisville?

Book flights to Louisville if you plan to visit one of these locations
Shepherdsville
Jeffersonville
Elizabethtown
Corydon
Bardstown

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See prices for flight routes from nearby airports that may be better suited for you.
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Top 4 airlines flying from Mesa to Louisville

Discover the top 4 airlines that operate flights from Mesa to Louisville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 29, 2026.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$182Average$464FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$266Average$474FlexibilityNo cancel feeOn-time71%
DeltaCheapest$296Average$450FlexibilityNo cancel feeOn-timeN/A
SouthwestCheapest$357Average$528FlexibilityNo cancel feeOn-time63%

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