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$103+ Cheap flights from Mesa, AZ to Louisville (SDF)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/13. Fares are subject to change and may not be available on all flights or dates of travel.
PHX — SDF
Jan 15 — Jan 221
Thu 1/15
Thu 1/22
1 adult, Economy
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1. Tell us where you want to go

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Cheapflights Tip: The best prices from Mesa to Louisville Intl are usually found in November or August, booked 79 days in advance, depart on a Monday or Wednesday and return on a Wednesday

Cheap flight deals from Mesa to Louisville

Cheapest flights from Mesa to Louisville
Explore the most affordable flight options available from Mesa to Louisville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 16, 2025.

This American Airlines deal was found by Cheapflights users on 12/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/203:47 pmPHX - SDF
1 stop6h 34mAmerican Airlines
Sun 1/46:27 amSDF - PHX
1 stop6h 43mAmerican Airlines
Deal found 12/14$425
This Delta deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/2312:45 pmPHX - SDF
1 stop8h 13mDelta
Tue 12/306:06 pmSDF - PHX
1 stop6h 25mDelta
Deal found 12/16$451
This American Airlines deal was found by Cheapflights users on 12/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/2412:58 amPHX - SDF
1 stop13h 01mAmerican Airlines
Tue 12/308:00 amSDF - PHX
1 stop7h 38mAmerican Airlines
Deal found 12/13$470
This United Airlines deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/2311:35 amPHX - SDF
2 stops8h 49mUnited Airlines
Tue 12/3010:50 amSDF - PHX
1 stop6h 57mUnited Airlines
Deal found 12/16$496
This United Airlines deal was found by Cheapflights users on 12/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/209:15 amPHX - SDF
2 stops9h 17mUnited Airlines
Sun 1/46:11 pmSDF - PHX
1 stop6h 47mUnited Airlines
Deal found 12/14$521
This Delta deal was found by Cheapflights users on 12/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/2012:45 pmPHX - SDF
1 stop8h 13mDelta
Sun 1/46:06 pmSDF - PHX
1 stop6h 27mDelta
Deal found 12/15$525
This United Airlines deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/161:45 pmPHX - SDF
1 stop6h 44mUnited Airlines
Mon 12/222:00 pmSDF - PHX
1 stop6h 38mUnited Airlines
Deal found 12/16$528
This United Airlines deal was found by Cheapflights users on 12/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/1611:33 amPHX - SDF
2 stops8h 36mUnited Airlines
Thu 12/1810:50 amSDF - PHX
1 stop6h 57mUnited Airlines
Deal found 12/14$533
This Southwest deal was found by Cheapflights users on 12/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/225:20 amPHX - SDF
1 stop11h 05mSouthwest
Wed 12/2411:45 amSDF - PHX
2 stops10h 15mSouthwest
Deal found 12/15$539
This United Airlines deal was found by Cheapflights users on 12/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/3012:38 pmPHX - SDF
1 stop5h 54mUnited Airlines
Sat 1/310:50 amSDF - PHX
2 stops9h 29mUnited Airlines
Deal found 12/14$541

Find flight deals from Mesa to Louisville

Keep the following information in mind while searching for Mesa to Louisville flight deals. Data was last updated December 16, 2025.

Round-trip from

$337
(Southwest)

One-way from

$103
(Kiwi.com)

Popular in

December

Cheapest in

November

Average price

$598
From Mesa to Louisville Intl
Search Deals
One-way flight from Mesa to Louisville Intl
Search Deals
High demand for flights, 4% potential price rise
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($10 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Mesa to Louisville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 16, 2025.
Use the filters below to find and compare flights from Mesa to Louisville that are best for you.

Fly from

Mesa

Fly to

Louisville

Route

Depart

Return

Price

PhoenixLouisville

PHX - SDF

PHXSDF

Phoenix Sky Harbor Intl

Sat 2/7

2:45 pm-10:05 pm

1 stop5h 20m

Louisville Intl

Mon 2/9

11:40 am-6:10 pm

1 stop8h 30m

$337

PhoenixLouisville

PHX - SDF

PHXSDF

Phoenix Sky Harbor Intl

Fri 2/20

7:00 am-2:19 pm

1 stop5h 19m

Louisville Intl

Sun 2/22

3:15 pm-9:21 pm

1 stop8h 06m

$337

PhoenixLouisville

PHX - SDF

PHXSDF

Phoenix Sky Harbor Intl

Mon 1/5

4:25 pm-12:20 am

1 stop5h 55m

Louisville Intl

Wed 1/14

6:00 am-10:10 am

1 stop6h 10m

$343

PhoenixLouisville

PHX - SDF

PHXSDF

Phoenix Sky Harbor Intl

Tue 1/27

12:10 pm-5:30 pm

Nonstop3h 20m

Louisville Intl

Wed 2/11

5:10 pm-7:45 pm

Nonstop4h 35m

$353

PhoenixLouisville

PHX - SDF

PHXSDF

Phoenix Sky Harbor Intl

Tue 1/27

7:00 am-6:11 pm

1 stop9h 11m

Louisville Intl

Thu 1/29

4:59 pm-12:11 am

1 stop9h 12m

$380

PhoenixLouisville

PHX - SDF

PHXSDF

Phoenix Sky Harbor Intl

Thu 1/15

6:00 am-5:10 pm

2 stops9h 10m

Louisville Intl

Thu 1/15

7:25 pm-11:40 pm

1 stop6h 15m

$382

PhoenixLouisville

PHX - SDF

PHXSDF

Phoenix Sky Harbor Intl

Fri 2/13

11:59 pm-8:40 am

1 stop6h 41m

Louisville Intl

Sun 2/15

12:00 pm-4:33 pm

1 stop6h 33m

$397

PhoenixLouisville

PHX - SDF

PHXSDF

Phoenix Sky Harbor Intl

Thu 2/19

2:52 pm-10:37 pm

1 stop5h 45m

Louisville Intl

Mon 2/23

5:35 am-10:20 am

1 stop6h 45m

$427

PhoenixLouisville

PHX - SDF

PHXSDF

Phoenix Sky Harbor Intl

Sat 1/17

8:20 am-2:41 pm

2 stops28h 21m

$124

PhoenixLouisville

PHX - SDF

PHXSDF

Phoenix Sky Harbor Intl

Tue 2/17

5:40 pm-2:38 pm

2 stops42h 58m

$124

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/15

Showing 1-10 of 17 results
1
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Best time to book a flight from Mesa to Louisville

Have a flexible travel schedule? Discover the best time to fly to Louisville from Mesa with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Mesa to Louisville

How far ahead should I book a flight from Mesa to Louisville?

Use this chart to determine the optimal time to book a round-trip flight from Mesa to Louisville. Price data was last updated on December 12, 2025.

To ensure you get the cheapest price possible for a flight from Mesa to Louisville, you should look to book at least 79 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.

What is the cheapest month to book a flight from Mesa to Louisville?

Currently, August is the cheapest month in which you can book a flight from Mesa to Louisville (average of $78). Flying from Mesa to Louisville in June is currently the most expensive (average of $177). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MS9 to SDF?

Find hourly flight availability from Mesa to Louisville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 16, 2025.

It’s optimal to fly from Mesa to Louisville in the evening. By choosing this option you can save up to 36% on the cost of your flight, compared to a flight in the afternoon.

What is the cheapest day to fly from Mesa to Louisville?

Use this chart to determine the cheapest time to fly round-trip from Mesa to Louisville. Price data was last updated on December 13, 2025.

Travelers seeking maximum savings on their Mesa to Louisville flight should consider departing on Tuesday evenings when fares are most often at their lowest. Tuesday afternoons flights should be avoided if possible as fares are typically the most expensive at this time.

How much does it cost to fly round-trip from Mesa to Louisville?

Reviews of airlines servicing Louisville

Get insights into the airlines that provide service to Louisville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Louisville. Reviews last updated December 16, 2025.
Peruse reviews from past customers who have flown with Southwest, Delta, and United Airlines from Mesa to Louisville to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
7.9
Good
4,250 reviews

Food

7.0

Entertainment

7.5

Boarding

8.1

Overall

7.9

Comfort

8.0

Crew

8.6

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
Southwest
7.9
Good
4,250 reviews
Southwest
7.9
Good
4,250 reviews

Food

7.0

Entertainment

7.5

Boarding

8.1

Overall

7.9

Comfort

8.0

Crew

8.6

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
Delta
7.9
Good
8,008 reviews
Southwest
7.9
Good
4,250 reviews

Food

7.0

Entertainment

7.5

Boarding

8.1

Overall

7.9

Comfort

8.0

Crew

8.6

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
United Airlines
7.4
Good
9,092 reviews
Southwest
7.9
Good
4,250 reviews

Food

7.0

Entertainment

7.5

Boarding

8.1

Overall

7.9

Comfort

8.0

Crew

8.6

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
American Airlines
7.2
Good
11,049 reviews
Southwest
7.9
Good
4,250 reviews

Food

7.0

Entertainment

7.5

Boarding

8.1

Overall

7.9

Comfort

8.0

Crew

8.6

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

Related info for your journey

Find useful and relevant information for your journey from Mesa to Louisville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Louisville from Mesa?

    Located just 5.3 mi from the city center, Louisville Intl is the airport most travelers will use when flying to Louisville from Mesa. Booking flights from Mesa to Louisville Intl (SDF) should be relatively easy as there are 0 daily inbound flights from Mesa from 4 different airlines.

  • How long is the flight from Mesa to Louisville?

    Departing from Mesa to Louisville will take you 5h 19m. The distance from Mesa to Louisville is about 1501 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines to fly from Mesa to Louisville one-way?

    The cheapest airlines for a one-way flight from Mesa to Louisville are American Airlines ($109), United Airlines ($177), and Southwest ($199).

  • Can I find deals for flights from Mesa to Louisville that include hotel bookings?

    Yes. In addition to deals on Mesa to Louisville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Mesa to Louisville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Mesa to Louisville.

  • Can I find deals for business class flights from Mesa to Louisville?

    Yes. Cheapflights offers flight deals from Mesa to Louisville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Mesa to Louisville?

    Currently, August is the cheapest month in which you can book a flight from Mesa to Louisville (average of $78). Flying from Mesa to Louisville in June is currently the most expensive (average of $177). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Louisville?

Book flights to Louisville if you plan to visit one of these locations
Shepherdsville
Jeffersonville
Elizabethtown
Corydon
Bardstown

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Top 4 airlines flying from Mesa to Louisville

Discover the top 4 airlines that operate flights from Mesa to Louisville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 16, 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$182Average$486FlexibilityNo cancel feeOn-time69%
DeltaCheapest$296Average$512FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$310Average$485FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$362Average$516FlexibilityNo cancel feeOn-time63%

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