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$99+ Cheap flights from Mesa, AZ to Louisville (SDF)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/22. Fares are subject to change and may not be available on all flights or dates of travel.
PHX — SDF
Apr 24 — May 11
Fri 4/24
Fri 5/1
1 adult, Economy
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Cheapflights Tip: The best prices from Mesa to Louisville Intl are usually found in November or August, booked 50 days in advance, depart on a Saturday or Tuesday and return on a Wednesday

Cheap flight deals from Mesa to Louisville

Cheapest flights from Mesa to Louisville
Explore the most affordable flight options available from Mesa to Louisville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 25, 2026.

This American Airlines deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/2012:38 am
PHX
-
SDF
1 stop6h 37m
American Airlines
Tue 4/287:01 pm
SDF
-
PHX
1 stop7h 58m
American Airlines
Deal found 3/24$197
This Southwest deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/227:45 am
PHX
-
SDF
1 stop7h 15m
Southwest
Wed 4/297:15 pm
SDF
-
PHX
1 stop6h 30m
Southwest
Deal found 3/23$198
This Southwest deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/1511:55 pm
PHX
-
SDF
1 stop7h 00m
Southwest
Mon 4/205:55 pm
SDF
-
PHX
1 stop8h 40m
Southwest
Deal found 3/23$217
This United Airlines deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/1611:59 pm
PHX
-
SDF
1 stop6h 11m
United Airlines
Mon 4/203:36 pm
SDF
-
PHX
1 stop7h 43m
United Airlines
Deal found 3/24$227
This Southwest deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/811:55 pm
PHX
-
SDF
1 stop8h 00m
Southwest
Tue 5/1212:10 pm
SDF
-
PHX
1 stop6h 10m
Southwest
Deal found 3/24$229
This Southwest deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/1611:55 pm
PHX
-
SDF
1 stop7h 00m
Southwest
Mon 4/202:40 pm
SDF
-
PHX
2 stops8h 10m
Southwest
Deal found 3/24$232
This American Airlines deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/231:47 pm
PHX
-
SDF
1 stop6h 24m
American Airlines
Mon 4/275:41 pm
SDF
-
PHX
1 stop8h 52m
American Airlines
Deal found 3/23$235
This Southwest deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/1511:55 pm
PHX
-
SDF
1 stop7h 10m
Southwest
Tue 5/197:00 am
SDF
-
PHX
2 stops9h 05m
Southwest
Deal found 3/22$241

Find flight deals from Mesa to Louisville

Keep the following information in mind while searching for Mesa to Louisville flight deals. Data was last updated March 25, 2026.

Round-trip from

$197
(American Airlines)

One-way from

$99
(Southwest)

Popular in

July

Cheapest in

November

Average price

$372
From Mesa to Louisville Intl
Search Deals
One-way flight from Mesa to Louisville Intl
Search Deals
Highest demand for flights based on searches. 2% potential increase in price ($11 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 1% potential price decrease ($7 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in March 2026
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Mesa to Louisville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 25, 2026.
Use the filters below to find and compare flights from Mesa to Louisville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

PhoenixLouisville

PHX - SDF

PHXSDF

Phoenix Sky Harbor Intl

Wed 4/15

10:10 pm-9:55 am

2 stops8h 45m

Louisville Intl

Mon 4/20

2:40 pm-7:50 pm

2 stops8h 10m

$228

PhoenixLouisville

PHX - SDF

PHXSDF

Phoenix Sky Harbor Intl

Thu 5/28

11:55 pm-11:40 am

1 stop8h 45m

Louisville Intl

Sat 5/30

5:35 am-6:15 pm

2 stops15h 40m

$283

PhoenixLouisville

PHX - SDF

PHXSDF

Phoenix Sky Harbor Intl

Fri 5/8

11:55 pm-10:55 am

1 stop8h 00m

Louisville Intl

Tue 5/12

8:25 am-9:20 am

Nonstop3h 55m

$285

PhoenixLouisville

PHX - SDF

PHXSDF

Phoenix Sky Harbor Intl

Fri 9/4

2:58 pm-11:59 pm

1 stop6h 01m

Louisville Intl

Sun 9/6

7:20 am-1:57 pm

1 stop9h 37m

$297

PhoenixLouisville

PHX - SDF

PHXSDF

Phoenix Sky Harbor Intl

Fri 8/7

11:50 pm-9:05 am

1 stop6h 15m

Louisville Intl

Sun 8/9

6:15 am-10:34 am

1 stop7h 19m

$297

PhoenixLouisville

PHX - SDF

PHXSDF

Phoenix Sky Harbor Intl

Thu 8/20

10:00 am-7:01 pm

1 stop6h 01m

Louisville Intl

Fri 8/21

10:15 am-1:57 pm

1 stop6h 42m

$297

PhoenixLouisville

PHX - SDF

PHXSDF

Phoenix Sky Harbor Intl

Sat 5/9

12:59 am-11:59 am

1 stop8h 00m

Louisville Intl

Sun 5/10

7:49 pm-11:29 pm

1 stop6h 40m

$297

PhoenixLouisville

PHX - SDF

PHXSDF

Phoenix Sky Harbor Intl

Fri 5/22

10:28 am-7:03 pm

1 stop5h 35m

Louisville Intl

Mon 5/25

6:05 am-10:49 am

1 stop7h 44m

$297

PhoenixLouisville

PHX - SDF

PHXSDF

Phoenix Sky Harbor Intl

Thu 8/20

10:00 am-8:52 pm

1 stop7h 52m

Louisville Intl

Sun 8/23

6:26 pm-10:14 pm

1 stop6h 48m

$297

PhoenixLouisville

PHX - SDF

PHXSDF

Phoenix Sky Harbor Intl

Thu 5/28

5:55 pm-12:15 am

Nonstop3h 20m

Louisville Intl

Sun 5/31

6:40 pm-12:05 am

1 stop8h 25m

$329

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/23

Showing 1-10 of 23 resultsSorted by cheapest first
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Best time to book a flight from Mesa to Louisville

Have a flexible travel schedule? Discover the best time to fly to Louisville from Mesa with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Mesa to Louisville

How far ahead should I book a flight from Mesa to Louisville?

Use this chart to determine the optimal time to book a round-trip flight from Mesa to Louisville. Price data was last updated on March 13, 2026.

To ensure you get the cheapest price possible for a flight from Mesa to Louisville, you should look to book at least 50 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.

What is the cheapest month to book a flight from Mesa to Louisville?

Currently, February is the cheapest month in which you can book a flight from Mesa to Louisville (average of $69). Flying from Mesa to Louisville in May is currently the most expensive (average of $180). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MS9 to SDF?

Find hourly flight availability from Mesa to Louisville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated March 25, 2026.

It’s optimal to fly from Mesa to Louisville in the evening. By choosing this option you can save up to 27% on the cost of your flight, compared to a flight in the afternoon.

Reviews of airlines servicing Louisville

Get insights into the airlines that provide service to Louisville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Louisville. Reviews last updated March 25, 2026.
Peruse reviews from past customers who have flown with Southwest,Delta, andUnited Airlines from Mesa to Louisville to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,332 reviews

Comfort

8.0

Crew

8.6

Overall

8.0

Boarding

8.1

Entertainment

7.5

Food

7.0

Reviews

1 / 20
2.0
Mediocre

Dominic,Mar 2026

MCO - SMF

I had to try and sleep on the floor of the Austin airport. I spent 12 hours there. The airline policies were so poor, that a near violent argument broke out between the people in front of me and the flight attendants - making for a super stressful situation at 30,000 feet. Garbage airline choice by Kayak Garbage idea to book a flight with a layover. Next time I will pay for a quality booking myself, and somehow force the company to reimburse it.
Southwest
8.0
Very good
4,332 reviews
Southwest
8.0
Very good
4,332 reviews

Comfort

8.0

Crew

8.6

Overall

8.0

Boarding

8.1

Entertainment

7.5

Food

7.0

Reviews

1 / 20
2.0
Mediocre

Dominic,Mar 2026

MCO - SMF

I had to try and sleep on the floor of the Austin airport. I spent 12 hours there. The airline policies were so poor, that a near violent argument broke out between the people in front of me and the flight attendants - making for a super stressful situation at 30,000 feet. Garbage airline choice by Kayak Garbage idea to book a flight with a layover. Next time I will pay for a quality booking myself, and somehow force the company to reimburse it.
Delta
7.9
Good
8,327 reviews
Southwest
8.0
Very good
4,332 reviews

Comfort

8.0

Crew

8.6

Overall

8.0

Boarding

8.1

Entertainment

7.5

Food

7.0

Reviews

1 / 20
2.0
Mediocre

Dominic,Mar 2026

MCO - SMF

I had to try and sleep on the floor of the Austin airport. I spent 12 hours there. The airline policies were so poor, that a near violent argument broke out between the people in front of me and the flight attendants - making for a super stressful situation at 30,000 feet. Garbage airline choice by Kayak Garbage idea to book a flight with a layover. Next time I will pay for a quality booking myself, and somehow force the company to reimburse it.
United Airlines
7.4
Good
9,478 reviews
Southwest
8.0
Very good
4,332 reviews

Comfort

8.0

Crew

8.6

Overall

8.0

Boarding

8.1

Entertainment

7.5

Food

7.0

Reviews

1 / 20
2.0
Mediocre

Dominic,Mar 2026

MCO - SMF

I had to try and sleep on the floor of the Austin airport. I spent 12 hours there. The airline policies were so poor, that a near violent argument broke out between the people in front of me and the flight attendants - making for a super stressful situation at 30,000 feet. Garbage airline choice by Kayak Garbage idea to book a flight with a layover. Next time I will pay for a quality booking myself, and somehow force the company to reimburse it.
American Airlines
7.1
Good
11,493 reviews
Southwest
8.0
Very good
4,332 reviews

Comfort

8.0

Crew

8.6

Overall

8.0

Boarding

8.1

Entertainment

7.5

Food

7.0

Reviews

1 / 20
2.0
Mediocre

Dominic,Mar 2026

MCO - SMF

I had to try and sleep on the floor of the Austin airport. I spent 12 hours there. The airline policies were so poor, that a near violent argument broke out between the people in front of me and the flight attendants - making for a super stressful situation at 30,000 feet. Garbage airline choice by Kayak Garbage idea to book a flight with a layover. Next time I will pay for a quality booking myself, and somehow force the company to reimburse it.

Related info for your journey

Find useful and relevant information for your journey from Mesa to Louisville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Louisville from Mesa?

    Located just 5.3 mi from the city center, Louisville Intl is the airport most travelers will use when flying to Louisville from Mesa. Booking flights from Mesa to Louisville Intl (SDF) should be relatively easy as there is 1 daily inbound flight from Mesa from 4 different airlines.

  • How long is the flight from Mesa to Louisville?

    Departing from Mesa to Louisville will take you 6h 01m. The distance from Mesa to Louisville is about 1501 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines to fly from Mesa to Louisville one-way?

    The cheapest airlines for a one-way flight from Mesa to Louisville are American Airlines ($113), United Airlines ($157), and Delta ($163).

  • What are the cheapest flights from Mesa to Louisville?

    The cheapest flight price from Mesa to Louisville is $332. On average you can expect to pay $484. The most popular route, (Phoenix Sky Harbor Intl - Louisville Intl), can usually be booked for $198.

  • Can I find deals for flights from Mesa to Louisville that include hotel bookings?

    Yes. In addition to deals on Mesa to Louisville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Mesa to Louisville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Mesa to Louisville.

  • Can I find deals for business class flights from Mesa to Louisville?

    Yes. Cheapflights offers flight deals from Mesa to Louisville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Mesa to Louisville?

    Currently, February is the cheapest month in which you can book a flight from Mesa to Louisville (average of $69). Flying from Mesa to Louisville in May is currently the most expensive (average of $180). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Louisville?

Book flights to Louisville if you plan to visit one of these locations
Shepherdsville
Jeffersonville
Elizabethtown
Corydon
Bardstown

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Top 4 airlines flying from Mesa to Louisville

Discover the top 4 airlines that operate flights from Mesa to Louisville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 25, 2026.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$182Average$448FlexibilityNo cancel feeOn-time69%
DeltaCheapest$256Average$450FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$256Average$448FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$277Average$529FlexibilityNo cancel feeOn-time63%

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