$119+ Cheap flights from Louisville (SDF) to Mesa, AZ
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/12. Fares are subject to change and may not be available on all flights or dates of travel.
SDF — PHX
Sep 15 — Sep 221
Round-trip
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from Louisville to Mesa with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheapflights Tip: The best prices from Louisville Intl to Mesa are usually found in June or August, booked 81 days in advance, depart on a Wednesday or Thursday and return on a Saturday
Cheap flight deals from Louisville to Mesa
Cheapest
Best
Last-minute
One-way
Cheapest flights from Louisville to MesaExplore the most affordable flight options available from Louisville to Mesa. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 16, 2026.
Explore the most affordable flight options available from Louisville to Mesa. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 16, 2026.
This United Airlines deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/319:17 am -
1 stop8h 40m
Wed 11/46:20 am -
1 stop6h 02m
Deal found 8/12![United Airlines logo]()
$237
This American Airlines deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/145:49 pm -
1 stop8h 32m
Wed 10/286:19 am -
1 stop8h 01m
Deal found 8/13![American Airlines logo]()
$238
This Southwest deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/316:35 am -
1 stop8h 25m
Wed 11/412:55 pm -
2 stops7h 55m
Deal found 8/12![Southwest logo]()
$242
This Delta deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/116:30 am -
1 stop6h 55m
Sat 9/1911:05 pm -
1 stop7h 47m
Deal found 8/13![Delta logo]()
$246
This Southwest deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/251:45 pm -
1 stop8h 15m
Tue 9/2910:35 am -
2 stops7h 05m
Deal found 8/12![Southwest logo]()
$251
This Delta deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/256:30 am -
1 stop9h 23m
Fri 10/211:59 pm -
1 stop7h 20m
Deal found 8/12![Delta logo]()
$255
This United Airlines deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/33:35 pm -
1 stop8h 18m
Tue 9/82:21 pm -
1 stop6h 35m
Deal found 8/11![United Airlines logo]()
$257
This Southwest deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/167:50 pm -
1 stop7h 50m
Fri 10/2311:00 am -
2 stops7h 05m
Deal found 8/12![Southwest logo]()
$260
This Delta deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/1012:34 pm -
1 stop6h 24m
Tue 9/2210:57 am -
1 stop7h 19m
Deal found 8/13![Delta logo]()
$268
This Delta deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/288:05 am -
1 stop7h 03m
Mon 8/3111:05 pm -
1 stop7h 49m
Deal found 8/14![Delta logo]()
$272
Best flights from Louisville to MesaDiscover carefully curated flight deals from Louisville to Mesa that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 16, 2026.
Discover carefully curated flight deals from Louisville to Mesa that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 16, 2026.
This Delta deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/263:26 pm -
1 stop8h 35m
Wed 11/412:57 pm -
1 stop7h 50m
Deal found 8/13![Delta logo]()
$237
This Southwest deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/196:15 pm -
2 stops8h 10m
Wed 10/2112:35 am -
1 stop6h 35m
Deal found 8/13![Southwest logo]()
$242
This United Airlines deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/710:25 am -
2 stops13h 24m
Sat 10/1010:25 am -
2 stops10h 34m
Deal found 8/11![United Airlines logo]()
$347
This Southwest deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/314:10 pm -
1 stop8h 20m
Tue 9/112:45 pm -
2 stops6h 45m
Deal found 8/12![Southwest logo]()
$242
This Delta deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/303:26 pm -
1 stop8h 35m
Tue 11/311:34 am -
1 stop5h 36m
Deal found 8/13![Delta logo]()
$246
This Southwest deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/311:55 pm -
Nonstop3h 55m
Sat 11/75:40 am -
1 stop7h 10m
Deal found 8/13![Southwest logo]()
$301
This United Airlines deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/307:10 am -
1 stop8h 46m
Sat 9/56:09 am -
2 stops11h 27m
Deal found 8/12![United Airlines logo]()
$377
This Delta deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/156:26 pm -
1 stop6h 56m
Sun 1/1712:55 am -
1 stop7h 17m
Deal found 8/16![Delta logo]()
$356
This United Airlines deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/177:10 am -
2 stops10h 45m
Sun 9/207:10 am -
1 stop8h 57m
Deal found 8/11![United Airlines logo]()
$377
This Delta deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/194:39 pm -
1 stop9h 35m
Tue 12/2211:50 pm -
1 stop8h 05m
Deal found 8/12![Delta logo]()
$407
Last-minute flights from Louisville to MesaDiscover last-minute flight deals from Louisville to Mesa. Data last updated August 16, 2026 and is based on user searches.
Discover last-minute flight deals from Louisville to Mesa. Data last updated August 16, 2026 and is based on user searches.
This Delta deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/288:05 am -
1 stop7h 03m
Mon 8/3111:05 pm -
1 stop7h 49m
Deal found 8/14![Delta logo]()
$272
This Delta deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/286:00 am -
1 stop6h 06m
Fri 9/1111:05 pm -
1 stop7h 47m
Deal found 8/13![Delta logo]()
$281
This United Airlines deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/33:35 pm -
1 stop8h 18m
Tue 9/82:21 pm -
1 stop6h 35m
Deal found 8/11![United Airlines logo]()
$257
This Delta deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/96:30 am -
1 stop9h 23m
Tue 9/2210:57 am -
1 stop7h 19m
Deal found 8/13![Delta logo]()
$237
This Delta deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/1012:34 pm -
1 stop6h 24m
Tue 9/2210:57 am -
1 stop7h 19m
Deal found 8/13![Delta logo]()
$268
This United Airlines deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/109:00 am -
1 stop6h 56m
Wed 9/169:45 am -
1 stop7h 47m
Deal found 8/11![United Airlines logo]()
$273
This Delta deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/116:30 am -
1 stop6h 55m
Sat 9/1911:05 pm -
1 stop7h 47m
Deal found 8/13![Delta logo]()
$246
This Delta deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/116:30 am -
1 stop6h 55m
Fri 9/1811:59 pm -
1 stop7h 20m
Deal found 8/13![Delta logo]()
$277
This United Airlines deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/155:15 am -
2 stops8h 22m
Tue 9/221:34 pm -
1 stop5h 55m
Deal found 8/12![United Airlines logo]()
$242
This Southwest deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/1511:50 am -
Nonstop3h 45m
Tue 9/2211:00 am -
1 stop9h 05m
Deal found 8/12![Southwest logo]()
$276
This Southwest deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/251:45 pm -
1 stop8h 15m
Tue 9/2910:35 am -
2 stops7h 05m
Deal found 8/12![Southwest logo]()
$251
This Delta deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/256:30 am -
1 stop9h 23m
Fri 10/211:59 pm -
1 stop7h 20m
Deal found 8/12![Delta logo]()
$255
One-way flights from Louisville to MesaSearch for one-way flight options from Louisville to Mesa. Find affordable one-way fares based on user searches. Data last updated August 16, 2026.
Search for one-way flight options from Louisville to Mesa. Find affordable one-way fares based on user searches. Data last updated August 16, 2026.
This Delta deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/126:30 am -
1 stop6h 55m
Deal found 8/12![Delta logo]()
$119
This Southwest deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/126:45 am -
2 stops6h 50m
Deal found 8/12![Southwest logo]()
$124
This Delta deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/116:30 am -
1 stop6h 55m
Deal found 8/14![Delta logo]()
$128
This Southwest deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/1211:50 am -
2 stops10h 10m
Deal found 8/13![Southwest logo]()
$133
This Kiwi.com deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/89:09 pm -
2 stops41h 28m
Deal found 8/12![Multiple Airlines logo]()
$139
This Delta deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/1012:34 pm -
1 stop6h 24m
Deal found 8/14![Delta logo]()
$150
This Kiwi.com deal was found by Cheapflights users on 8/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/168:47 am -
1 stop17h 46m
Deal found 8/15![Multiple Airlines logo]()
$152
This United Airlines deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/67:10 am -
1 stop6h 58m
Deal found 8/13![United Airlines logo]()
$154
This United Airlines deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/225:15 am -
2 stops8h 22m
Deal found 8/12![United Airlines logo]()
$157
This United Airlines deal was found by Cheapflights users on 8/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/95:15 am -
2 stops8h 22m
Deal found 8/15![United Airlines logo]()
$159
This United Airlines deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/115:15 am -
2 stops8h 22m
Deal found 8/12![United Airlines logo]()
$162
Find flight deals from Louisville to Mesa
Keep the following information in mind while searching for Louisville to Mesa flight deals. Data was last updated August 16, 2026.
Round-trip from | $237 (United Airlines) |
|---|---|
One-way from | $119 (Delta) |
Popular in | December |
Cheapest in | June |
Average price | $396 |
Cheapflights Fare Finder
Customize your flight search to find flights from Louisville to Mesa that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 16, 2026.
Use the filters below to find and compare flights from Louisville to Mesa that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
LouisvillePhoenix
SDF Louisville Intl - PHX Phoenix Sky Harbor Intl
SDFPHX
Louisville Intl
Mon 10/26
3:26 pm-9:01 pm
1 stop8h 35m
Phoenix Sky Harbor Intl
Wed 11/4
12:57 pm-10:47 pm
1 stop7h 50m
$237
LouisvillePhoenix
SDF Louisville Intl - PHX Phoenix Sky Harbor Intl
SDFPHX
Louisville Intl
Mon 10/19
6:15 pm-11:25 pm
2 stops8h 10m
Phoenix Sky Harbor Intl
Wed 10/21
12:35 am-10:10 am
1 stop6h 35m
$242
LouisvillePhoenix
SDF Louisville Intl - PHX Phoenix Sky Harbor Intl
SDFPHX
Louisville Intl
Mon 8/31
4:10 pm-9:30 pm
1 stop8h 20m
Phoenix Sky Harbor Intl
Tue 9/1
12:45 pm-10:30 pm
2 stops6h 45m
$242
LouisvillePhoenix
SDF Louisville Intl - PHX Phoenix Sky Harbor Intl
SDFPHX
Louisville Intl
Fri 10/30
3:26 pm-9:01 pm
1 stop8h 35m
Phoenix Sky Harbor Intl
Tue 11/3
11:34 am-7:10 pm
1 stop5h 36m
$246
Quickest round-trip
LouisvillePhoenix
SDF Louisville Intl - PHX Phoenix Sky Harbor Intl
SDFPHX
Louisville Intl
Sat 10/31
1:55 pm-2:50 pm
Nonstop3h 55m
Phoenix Sky Harbor Intl
Sat 11/7
5:40 am-2:50 pm
1 stop7h 10m
$301
LouisvillePhoenix
SDF Louisville Intl - PHX Phoenix Sky Harbor Intl
SDFPHX
Louisville Intl
Wed 10/7
10:25 am-8:49 pm
2 stops13h 24m
Phoenix Sky Harbor Intl
Sat 10/10
10:25 am-11:59 pm
2 stops10h 34m
$347
LouisvillePhoenix
SDF Louisville Intl - PHX Phoenix Sky Harbor Intl
SDFPHX
Louisville Intl
Fri 1/15
6:26 pm-11:22 pm
1 stop6h 56m
Phoenix Sky Harbor Intl
Sun 1/17
12:55 am-10:12 am
1 stop7h 17m
$356
LouisvillePhoenix
SDF Louisville Intl - PHX Phoenix Sky Harbor Intl
SDFPHX
Louisville Intl
Sun 8/30
7:10 am-12:56 pm
1 stop8h 46m
Phoenix Sky Harbor Intl
Sat 9/5
6:09 am-8:36 pm
2 stops11h 27m
$377
LouisvillePhoenix
SDF Louisville Intl - PHX Phoenix Sky Harbor Intl
SDFPHX
Louisville Intl
Thu 9/17
7:10 am-2:55 pm
2 stops10h 45m
Phoenix Sky Harbor Intl
Sun 9/20
7:10 am-7:07 pm
1 stop8h 57m
$377
LouisvillePhoenix
SDF Louisville Intl - PHX Phoenix Sky Harbor Intl
SDFPHX
Louisville Intl
Sat 12/19
4:39 pm-12:14 am
1 stop9h 35m
Phoenix Sky Harbor Intl
Tue 12/22
11:50 pm-9:55 am
1 stop8h 05m
$407
Showing 1-10 of 21 resultsSorted by cheapest first
Best time to book a flight from Louisville to Mesa
Have a flexible travel schedule? Discover the best time to fly to Mesa from Louisville with our price prediction graph.
SDF-PHX
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Louisville to Mesa
SDF-MS9
SDF-PHX
What is the cheapest time of day to fly from SDF to MS9?
Find hourly flight availability from Louisville to Mesa. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated August 16, 2026.
A simple way to save on the total cost of your ticket is to fly from Louisville to Mesa in the afternoon. If you’re flexible enough to do this you can expect to save up to 34% on your trip compared to booking a flight in the evening.
How much does it cost to fly round-trip from Louisville to Mesa?
Airfare is below average for this route at the moment.
Louisville to Mesa flights typically cost between $306 and $427 in October.The cheapest round-trip price found within the last 5 days was $237 on United Airlines (Oct 31-Nov 4).
Reviews of airlines servicing Mesa
Get insights into the airlines that provide service to Mesa. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Mesa. Reviews last updated August 16, 2026.
Peruse reviews from past customers who have flown with Southwest,Delta, andUnited Airlines from Louisville to Mesa to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Food
7.0
Entertainment
7.5
Comfort
8.0
Crew
8.6
Overall
8.0
Boarding
8.1
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Food
7.0
Entertainment
7.5
Comfort
8.0
Crew
8.6
Overall
8.0
Boarding
8.1
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Food
7.0
Entertainment
7.5
Comfort
8.0
Crew
8.6
Overall
8.0
Boarding
8.1
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Food
7.0
Entertainment
7.5
Comfort
8.0
Crew
8.6
Overall
8.0
Boarding
8.1
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Food
7.0
Entertainment
7.5
Comfort
8.0
Crew
8.6
Overall
8.0
Boarding
8.1
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Related info for your journey
Find useful and relevant information for your journey from Louisville to Mesa. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Complete your trip
Flights by cabin class
Other flight options
Other flights from Louisville
Popular flights
Top destinations
Alternative routes for Louisville to Mesa
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Mesa by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Louisville to Mesa by cabin class
Find flights from Louisville to Mesa, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Louisville and Mesa flights
Browse other Louisville and Mesa flight options. Last updated on August 16, 2026.
Other flights from Louisville
Browse through other flights departing from Louisville. Flights are based on user searches made on Cheapflights and were last updated on August 16, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Louisville to Mesa flights
Consider these flights traveling from Louisville to Mesa.
Top 4 airlines flying from Louisville to Mesa
Discover the top 4 airlines that operate flights from Louisville to Mesa. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 16, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$218 | Average$399 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$236 | Average$391 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$266 | Average$367 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$307 | Average$486 | FlexibilityNo cancel fee | On-time63% |