$149+ Cheap flights from Mesa, AZ to Louisville (SDF)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/24. Fares are subject to change and may not be available on all flights or dates of travel.
PHX — SDF
Jul 29 — Aug 51
Round-trip
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from Mesa to Louisville with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheapflights Tip: The best prices from Mesa to Louisville Intl are usually found in November or August, booked 79 days in advance, depart on a Saturday or Thursday and return on a Wednesday
Cheap flight deals from Mesa to Louisville
Cheapest
Best
Last-minute
One-way
Cheapest flights from Mesa to LouisvilleExplore the most affordable flight options available from Mesa to Louisville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 29, 2026.
Explore the most affordable flight options available from Mesa to Louisville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 29, 2026.
This American Airlines deal was found by Cheapflights users on 6/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/61:48 pm
PHX
- SDF
1 stop6h 23m
American Airlines
Wed 8/127:03 am
SDF
- PHX
1 stop7h 14m
American Airlines
Deal found 6/24![American Airlines logo]()
$296
This Delta deal was found by Cheapflights users on 6/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/163:00 pm
PHX
- SDF
1 stop6h 26m
Delta
Tue 7/216:00 am
SDF
- PHX
1 stop6h 01m
Delta
Deal found 6/26![Delta logo]()
$297
This United Airlines deal was found by Cheapflights users on 6/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/272:26 pm
PHX
- SDF
1 stop6h 33m
United Airlines
Sun 8/305:15 am
SDF
- PHX
2 stops8h 19m
United Airlines
Deal found 6/25![United Airlines logo]()
$302
This American Airlines deal was found by Cheapflights users on 6/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/1812:36 am
PHX
- SDF
1 stop7h 03m
American Airlines
Wed 7/227:48 pm
SDF
- PHX
1 stop6h 13m
American Airlines
Deal found 6/25![American Airlines logo]()
$318
This United Airlines deal was found by Cheapflights users on 6/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/126:00 am
PHX
- SDF
1 stop5h 29m
United Airlines
Sat 8/151:50 pm
SDF
- PHX
2 stops9h 34m
United Airlines
Deal found 6/27![United Airlines logo]()
$319
This United Airlines deal was found by Cheapflights users on 6/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/1210:15 am
PHX
- SDF
2 stops9h 14m
United Airlines
Sun 8/167:25 am
SDF
- PHX
1 stop5h 57m
United Airlines
Deal found 6/27![United Airlines logo]()
$322
This United Airlines deal was found by Cheapflights users on 6/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/211:34 pm
PHX
- SDF
1 stop5h 57m
United Airlines
Sat 8/2210:23 am
SDF
- PHX
2 stops9h 47m
United Airlines
Deal found 6/24![United Airlines logo]()
$325
This American Airlines deal was found by Cheapflights users on 6/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/165:00 am
PHX
- SDF
1 stop9h 14m
American Airlines
Fri 9/182:41 pm
SDF
- PHX
1 stop9h 16m
American Airlines
Deal found 6/25![American Airlines logo]()
$327
This United Airlines deal was found by Cheapflights users on 6/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/62:48 pm
PHX
- SDF
1 stop6h 11m
United Airlines
Wed 8/125:15 am
SDF
- PHX
2 stops8h 22m
United Airlines
Deal found 6/25![United Airlines logo]()
$334
This American Airlines deal was found by Cheapflights users on 6/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/101:14 pm
PHX
- SDF
1 stop7h 11m
American Airlines
Sun 9/135:06 am
SDF
- PHX
1 stop6h 55m
American Airlines
Deal found 6/29![American Airlines logo]()
$338
This Southwest deal was found by Cheapflights users on 6/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/69:15 am
PHX
- SDF
1 stop5h 05m
Southwest
Wed 8/1211:50 am
SDF
- PHX
Nonstop3h 45m
Southwest
Deal found 6/25![Southwest logo]()
$347
This American Airlines deal was found by Cheapflights users on 6/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/2612:21 pm
PHX
- SDF
1 stop7h 50m
American Airlines
Thu 9/36:05 am
SDF
- PHX
1 stop8h 18m
American Airlines
Deal found 6/28![American Airlines logo]()
$351
Best flights from Mesa to LouisvilleDiscover carefully curated flight deals from Mesa to Louisville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 29, 2026.
Discover carefully curated flight deals from Mesa to Louisville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 29, 2026.
This Delta deal was found by Cheapflights users on 6/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/1611:55 pm
PHX
- SDF
1 stop6h 59m
Delta
Tue 10/207:00 am
SDF
- PHX
1 stop7h 17m
Delta
Deal found 6/26![Delta logo]()
$297
This United Airlines deal was found by Cheapflights users on 6/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/2111:28 am
PHX
- SDF
1 stop6h 08m
United Airlines
Sat 8/221:50 pm
SDF
- PHX
2 stops9h 34m
United Airlines
Deal found 6/24![United Airlines logo]()
$302
This Southwest deal was found by Cheapflights users on 6/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/1211:35 am
PHX
- SDF
Nonstop3h 20m
Southwest
Sat 8/152:55 pm
SDF
- PHX
1 stop8h 35m
Southwest
Deal found 6/29![Southwest logo]()
$347
This Delta deal was found by Cheapflights users on 6/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/511:56 pm
PHX
- SDF
1 stop5h 50m
Delta
Tue 8/1810:34 am
SDF
- PHX
1 stop6h 16m
Delta
Deal found 6/24![Delta logo]()
$297
This United Airlines deal was found by Cheapflights users on 6/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/272:26 pm
PHX
- SDF
1 stop6h 33m
United Airlines
Sun 8/305:15 am
SDF
- PHX
2 stops8h 19m
United Airlines
Deal found 6/25![United Airlines logo]()
$302
This Delta deal was found by Cheapflights users on 6/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/2311:56 pm
PHX
- SDF
1 stop5h 50m
Delta
Wed 9/26:50 am
SDF
- PHX
1 stop7h 02m
Delta
Deal found 6/27![Delta logo]()
$297
This United Airlines deal was found by Cheapflights users on 6/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/1210:15 am
PHX
- SDF
2 stops9h 14m
United Airlines
Sat 8/157:25 am
SDF
- PHX
1 stop5h 57m
United Airlines
Deal found 6/29![United Airlines logo]()
$322
This United Airlines deal was found by Cheapflights users on 6/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/196:00 am
PHX
- SDF
2 stops8h 39m
United Airlines
Tue 9/229:00 am
SDF
- PHX
1 stop6h 56m
United Airlines
Deal found 6/25![United Airlines logo]()
$360
This United Airlines deal was found by Cheapflights users on 6/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/2411:52 pm
PHX
- SDF
1 stop6h 45m
United Airlines
Sun 9/275:15 am
SDF
- PHX
1 stop6h 39m
United Airlines
Deal found 6/24![United Airlines logo]()
$397
This United Airlines deal was found by Cheapflights users on 6/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/1611:32 am
PHX
- SDF
1 stop8h 04m
United Airlines
Fri 9/185:15 am
SDF
- PHX
2 stops13h 01m
United Airlines
Deal found 6/25![United Airlines logo]()
$402
Last-minute flights from Mesa to LouisvilleDiscover last-minute flight deals from Mesa to Louisville. Data last updated June 29, 2026 and is based on user searches.
Discover last-minute flight deals from Mesa to Louisville. Data last updated June 29, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 6/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/61:15 am
PHX
- SDF
1 stop5h 48m
American Airlines
Mon 7/207:50 pm
SDF
- PHX
1 stop6h 38m
American Airlines
Deal found 6/24![American Airlines logo]()
$371
This American Airlines deal was found by Cheapflights users on 6/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/710:15 am
PHX
- SDF
1 stop8h 49m
American Airlines
Thu 7/167:10 pm
SDF
- PHX
1 stop8h 04m
American Airlines
Deal found 6/27![American Airlines logo]()
$372
This United Airlines deal was found by Cheapflights users on 6/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/76:50 am
PHX
- SDF
1 stop7h 13m
United Airlines
Sun 7/127:15 am
SDF
- PHX
1 stop6h 48m
United Airlines
Deal found 6/27![United Airlines logo]()
$397
This United Airlines deal was found by Cheapflights users on 6/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/92:48 pm
PHX
- SDF
1 stop6h 11m
United Airlines
Sun 7/127:15 am
SDF
- PHX
1 stop6h 48m
United Airlines
Deal found 6/25![United Airlines logo]()
$357
This Delta deal was found by Cheapflights users on 6/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/155:45 am
PHX
- SDF
1 stop9h 04m
Delta
Tue 7/216:00 am
SDF
- PHX
1 stop6h 01m
Delta
Deal found 6/26![Delta logo]()
$358
This Delta deal was found by Cheapflights users on 6/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/156:00 am
PHX
- SDF
1 stop7h 47m
Delta
Thu 7/235:28 pm
SDF
- PHX
1 stop7h 20m
Delta
Deal found 6/26![Delta logo]()
$379
This Kiwi.com deal was found by Cheapflights users on 6/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/159:58 pm
PHX
- SDF
2 stops32h 57m
Multiple Airlines
Wed 7/229:21 am
SDF
- PHX
1 stop9h 10m
Multiple Airlines
Deal found 6/26![Multiple Airlines logo]()
$385
This Delta deal was found by Cheapflights users on 6/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/163:00 pm
PHX
- SDF
1 stop6h 26m
Delta
Tue 7/216:00 am
SDF
- PHX
1 stop6h 01m
Delta
Deal found 6/26![Delta logo]()
$297
This American Airlines deal was found by Cheapflights users on 6/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/1812:36 am
PHX
- SDF
1 stop7h 03m
American Airlines
Wed 7/227:48 pm
SDF
- PHX
1 stop6h 13m
American Airlines
Deal found 6/25![American Airlines logo]()
$318
This Southwest deal was found by Cheapflights users on 6/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/187:50 am
PHX
- SDF
Nonstop3h 25m
Southwest
Fri 7/246:05 pm
SDF
- PHX
1 stop5h 50m
Southwest
Deal found 6/25![Southwest logo]()
$367
This American Airlines deal was found by Cheapflights users on 6/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/202:03 pm
PHX
- SDF
1 stop7h 31m
American Airlines
Fri 7/247:50 pm
SDF
- PHX
1 stop6h 38m
American Airlines
Deal found 6/28![American Airlines logo]()
$327
This Southwest deal was found by Cheapflights users on 6/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/282:20 pm
PHX
- SDF
1 stop7h 00m
Southwest
Tue 8/47:05 am
SDF
- PHX
2 stops6h 55m
Southwest
Deal found 6/28![Southwest logo]()
$377
One-way flights from Mesa to LouisvilleSearch for one-way flight options from Mesa to Louisville. Find affordable one-way fares based on user searches. Data last updated June 29, 2026.
Search for one-way flight options from Mesa to Louisville. Find affordable one-way fares based on user searches. Data last updated June 29, 2026.
This Delta deal was found by Cheapflights users on 6/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/2411:05 pm
PHX
- SDF
1 stop7h 47m
Delta
Deal found 6/25![Delta logo]()
$149
This United Airlines deal was found by Cheapflights users on 6/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/146:00 am
PHX
- SDF
2 stops10h 18m
United Airlines
Deal found 6/28![United Airlines logo]()
$154
This Kiwi.com deal was found by Cheapflights users on 6/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/1910:09 pm
PHX
- SDF
2 stops32h 46m
Multiple Airlines
Deal found 6/24![Multiple Airlines logo]()
$162
This Southwest deal was found by Cheapflights users on 6/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/2511:35 am
PHX
- SDF
Nonstop3h 20m
Southwest
Deal found 6/27![Southwest logo]()
$169
This American Airlines deal was found by Cheapflights users on 6/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/1812:36 am
PHX
- SDF
1 stop7h 03m
American Airlines
Deal found 6/24![American Airlines logo]()
$170
This Kiwi.com deal was found by Cheapflights users on 6/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/2510:09 pm
PHX
- SDF
3 stops56h 40m
Multiple Airlines
Deal found 6/28![Multiple Airlines logo]()
$176
This Kiwi.com deal was found by Cheapflights users on 6/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/2410:33 pm
PHX
- SDF
2 stops36h 43m
Multiple Airlines
Deal found 6/25![Multiple Airlines logo]()
$182
This Kiwi.com deal was found by Cheapflights users on 6/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/229:03 am
PHX
- SDF
3 stops45h 46m
Multiple Airlines
Deal found 6/27![Multiple Airlines logo]()
$183
This Kiwi.com deal was found by Cheapflights users on 6/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/299:03 am
PHX
- SDF
3 stops46h 26m
Multiple Airlines
Deal found 6/28![Multiple Airlines logo]()
$188
This Southwest deal was found by Cheapflights users on 6/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/257:50 am
PHX
- SDF
Nonstop3h 25m
Southwest
Deal found 6/28![Southwest logo]()
$189
Find flight deals from Mesa to Louisville
Keep the following information in mind while searching for Mesa to Louisville flight deals. Data was last updated June 29, 2026.
Round-trip from | $296 (American Airlines) |
|---|---|
One-way from | $149 (Delta) |
Popular in | October |
Cheapest in | November |
Average price | $434 |
Cheapflights Fare Finder
Customize your flight search to find flights from Mesa to Louisville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 29, 2026.
Use the filters below to find and compare flights from Mesa to Louisville that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
PhoenixLouisville
PHX - SDF
PHXSDF
Phoenix Sky Harbor Intl
Fri 10/16
11:55 pm-9:54 am
1 stop6h 59m
Louisville Intl
Tue 10/20
7:00 am-11:17 am
1 stop7h 17m
$297
PhoenixLouisville
PHX - SDF
PHXSDF
Phoenix Sky Harbor Intl
Wed 8/5
11:56 pm-8:46 am
1 stop5h 50m
Louisville Intl
Tue 8/18
10:34 am-1:50 pm
1 stop6h 16m
$297
PhoenixLouisville
PHX - SDF
PHXSDF
Phoenix Sky Harbor Intl
Sun 8/23
11:56 pm-8:46 am
1 stop5h 50m
Louisville Intl
Wed 9/2
6:50 am-10:52 am
1 stop7h 02m
$297
PhoenixLouisville
PHX - SDF
PHXSDF
Phoenix Sky Harbor Intl
Fri 8/21
11:28 am-8:36 pm
1 stop6h 08m
Louisville Intl
Sat 8/22
1:50 pm-8:24 pm
2 stops9h 34m
$302
PhoenixLouisville
PHX - SDF
PHXSDF
Phoenix Sky Harbor Intl
Thu 8/27
2:26 pm-11:59 pm
1 stop6h 33m
Louisville Intl
Sun 8/30
5:15 am-10:34 am
2 stops8h 19m
$302
PhoenixLouisville
PHX - SDF
PHXSDF
Phoenix Sky Harbor Intl
Wed 8/12
10:15 am-10:29 pm
2 stops9h 14m
Louisville Intl
Sat 8/15
7:25 am-10:22 am
1 stop5h 57m
$322
Quickest round-trip
PhoenixLouisville
PHX - SDF
PHXSDF
Phoenix Sky Harbor Intl
Wed 8/12
11:35 am-5:55 pm
Nonstop3h 20m
Louisville Intl
Sat 8/15
2:55 pm-8:30 pm
1 stop8h 35m
$347
PhoenixLouisville
PHX - SDF
PHXSDF
Phoenix Sky Harbor Intl
Sat 9/19
6:00 am-5:39 pm
2 stops8h 39m
Louisville Intl
Tue 9/22
9:00 am-12:56 pm
1 stop6h 56m
$360
PhoenixLouisville
PHX - SDF
PHXSDF
Phoenix Sky Harbor Intl
Thu 9/24
11:52 pm-9:37 am
1 stop6h 45m
Louisville Intl
Sun 9/27
5:15 am-8:54 am
1 stop6h 39m
$397
PhoenixLouisville
PHX - SDF
PHXSDF
Phoenix Sky Harbor Intl
Wed 9/16
11:32 am-10:36 pm
1 stop8h 04m
Louisville Intl
Fri 9/18
5:15 am-3:16 pm
2 stops13h 01m
$402
Showing 1-10 of 20 resultsSorted by cheapest first
Best time to book a flight from Mesa to Louisville
Have a flexible travel schedule? Discover the best time to fly to Louisville from Mesa with our price prediction graph.
PHX-SDF
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Mesa to Louisville
MS9-SDF
PHX-SDF
What is the cheapest time of day to fly from MS9 to SDF?
Find hourly flight availability from Mesa to Louisville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated June 29, 2026.
It’s optimal to fly from Mesa to Louisville in the evening. By choosing this option you can save up to 27% on the cost of your flight, compared to a flight in the afternoon.
How much does it cost to fly round-trip from Mesa to Louisville?
Reviews of airlines servicing Louisville
Get insights into the airlines that provide service to Louisville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Louisville. Reviews last updated June 29, 2026.
Peruse reviews from past customers who have flown with Southwest,Delta, andUnited Airlines from Mesa to Louisville to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Boarding
8.1
Food
7.0
Crew
8.6
Overall
7.9
Entertainment
7.5
Comfort
8.0
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Boarding
8.1
Food
7.0
Crew
8.6
Overall
7.9
Entertainment
7.5
Comfort
8.0
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Boarding
8.1
Food
7.0
Crew
8.6
Overall
7.9
Entertainment
7.5
Comfort
8.0
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Boarding
8.1
Food
7.0
Crew
8.6
Overall
7.9
Entertainment
7.5
Comfort
8.0
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Boarding
8.1
Food
7.0
Crew
8.6
Overall
7.9
Entertainment
7.5
Comfort
8.0
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Boarding
8.1
Food
7.0
Crew
8.6
Overall
7.9
Entertainment
7.5
Comfort
8.0
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Related info for your journey
Find useful and relevant information for your journey from Mesa to Louisville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Louisville?
Book flights to Louisville if you plan to visit one of these locationsCorydon
Shepherdsville
Elizabethtown
Jeffersonville
Bardstown
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Complete your trip
Flights by cabin class
Louisville flight routes
Other flight options
Popular flights
Top destinations
Alternative routes for Mesa to Louisville
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Louisville by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Mesa to Louisville by cabin class
Find flights from Mesa to Louisville, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Other flights to Louisville
Explore flights to Louisville departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on June 29, 2026.
Mesa and Louisville flights
Browse other Mesa and Louisville flight options. Last updated on June 29, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Mesa to Louisville flights
Consider these flights traveling from Mesa to Louisville.
Top 5 airlines flying from Mesa to Louisville
Discover the top 5 airlines that operate flights from Mesa to Louisville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 29, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$182 | Average$396 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$238 | Average$318 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$256 | Average$411 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$261 | Average$381 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$270 | Average$490 | FlexibilityNo cancel fee | On-time63% |