Louisville

$149+ Cheap flights from Mesa, AZ to Louisville (SDF)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/24. Fares are subject to change and may not be available on all flights or dates of travel.
PHX — SDF
Jul 29 — Aug 51
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Find cheap flights from Mesa to Louisville with Cheapflights

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Cheapflights Tip: The best prices from Mesa to Louisville Intl are usually found in November or August, booked 79 days in advance, depart on a Saturday or Thursday and return on a Wednesday

Cheap flight deals from Mesa to Louisville

Cheapest flights from Mesa to Louisville
Explore the most affordable flight options available from Mesa to Louisville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 29, 2026.

This American Airlines deal was found by Cheapflights users on 6/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/61:48 pm
PHX
-
SDF
1 stop6h 23m
American Airlines
Wed 8/127:03 am
SDF
-
PHX
1 stop7h 14m
American Airlines
Deal found 6/24$296
This Delta deal was found by Cheapflights users on 6/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/163:00 pm
PHX
-
SDF
1 stop6h 26m
Delta
Tue 7/216:00 am
SDF
-
PHX
1 stop6h 01m
Delta
Deal found 6/26$297
This United Airlines deal was found by Cheapflights users on 6/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/272:26 pm
PHX
-
SDF
1 stop6h 33m
United Airlines
Sun 8/305:15 am
SDF
-
PHX
2 stops8h 19m
United Airlines
Deal found 6/25$302
This American Airlines deal was found by Cheapflights users on 6/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/1812:36 am
PHX
-
SDF
1 stop7h 03m
American Airlines
Wed 7/227:48 pm
SDF
-
PHX
1 stop6h 13m
American Airlines
Deal found 6/25$318
This United Airlines deal was found by Cheapflights users on 6/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/126:00 am
PHX
-
SDF
1 stop5h 29m
United Airlines
Sat 8/151:50 pm
SDF
-
PHX
2 stops9h 34m
United Airlines
Deal found 6/27$319
This United Airlines deal was found by Cheapflights users on 6/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/1210:15 am
PHX
-
SDF
2 stops9h 14m
United Airlines
Sun 8/167:25 am
SDF
-
PHX
1 stop5h 57m
United Airlines
Deal found 6/27$322
This United Airlines deal was found by Cheapflights users on 6/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/211:34 pm
PHX
-
SDF
1 stop5h 57m
United Airlines
Sat 8/2210:23 am
SDF
-
PHX
2 stops9h 47m
United Airlines
Deal found 6/24$325
This American Airlines deal was found by Cheapflights users on 6/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/165:00 am
PHX
-
SDF
1 stop9h 14m
American Airlines
Fri 9/182:41 pm
SDF
-
PHX
1 stop9h 16m
American Airlines
Deal found 6/25$327
This United Airlines deal was found by Cheapflights users on 6/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/62:48 pm
PHX
-
SDF
1 stop6h 11m
United Airlines
Wed 8/125:15 am
SDF
-
PHX
2 stops8h 22m
United Airlines
Deal found 6/25$334
This American Airlines deal was found by Cheapflights users on 6/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/101:14 pm
PHX
-
SDF
1 stop7h 11m
American Airlines
Sun 9/135:06 am
SDF
-
PHX
1 stop6h 55m
American Airlines
Deal found 6/29$338
This Southwest deal was found by Cheapflights users on 6/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/69:15 am
PHX
-
SDF
1 stop5h 05m
Southwest
Wed 8/1211:50 am
SDF
-
PHX
Nonstop3h 45m
Southwest
Deal found 6/25$347
This American Airlines deal was found by Cheapflights users on 6/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/2612:21 pm
PHX
-
SDF
1 stop7h 50m
American Airlines
Thu 9/36:05 am
SDF
-
PHX
1 stop8h 18m
American Airlines
Deal found 6/28$351

Find flight deals from Mesa to Louisville

Keep the following information in mind while searching for Mesa to Louisville flight deals. Data was last updated June 29, 2026.

Round-trip from

$296
(American Airlines)

One-way from

$149
(Delta)

Popular in

October

Cheapest in

November

Average price

$434
From Mesa to Louisville Intl
One-way flight from Mesa to Louisville Intl
Highest demand for flights based on searches. 2% potential increase in price ($11 potential increase over avg. RT price).
Cheapest flight prices on average. 1% potential price decrease ($6 potential savings vs. average RT price).
Average for round-trip flights in June 2026

Cheapflights Fare Finder

 
Customize your flight search to find flights from Mesa to Louisville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 29, 2026.
Use the filters below to find and compare flights from Mesa to Louisville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

PhoenixLouisville

PHX - SDF

PHXSDF

Phoenix Sky Harbor Intl

Fri 10/16

11:55 pm-9:54 am

1 stop6h 59m

Louisville Intl

Tue 10/20

7:00 am-11:17 am

1 stop7h 17m

$297

PhoenixLouisville

PHX - SDF

PHXSDF

Phoenix Sky Harbor Intl

Wed 8/5

11:56 pm-8:46 am

1 stop5h 50m

Louisville Intl

Tue 8/18

10:34 am-1:50 pm

1 stop6h 16m

$297

PhoenixLouisville

PHX - SDF

PHXSDF

Phoenix Sky Harbor Intl

Sun 8/23

11:56 pm-8:46 am

1 stop5h 50m

Louisville Intl

Wed 9/2

6:50 am-10:52 am

1 stop7h 02m

$297

PhoenixLouisville

PHX - SDF

PHXSDF

Phoenix Sky Harbor Intl

Fri 8/21

11:28 am-8:36 pm

1 stop6h 08m

Louisville Intl

Sat 8/22

1:50 pm-8:24 pm

2 stops9h 34m

$302

PhoenixLouisville

PHX - SDF

PHXSDF

Phoenix Sky Harbor Intl

Thu 8/27

2:26 pm-11:59 pm

1 stop6h 33m

Louisville Intl

Sun 8/30

5:15 am-10:34 am

2 stops8h 19m

$302

PhoenixLouisville

PHX - SDF

PHXSDF

Phoenix Sky Harbor Intl

Wed 8/12

10:15 am-10:29 pm

2 stops9h 14m

Louisville Intl

Sat 8/15

7:25 am-10:22 am

1 stop5h 57m

$322
Quickest round-trip

PhoenixLouisville

PHX - SDF

PHXSDF

Phoenix Sky Harbor Intl

Wed 8/12

11:35 am-5:55 pm

Nonstop3h 20m

Louisville Intl

Sat 8/15

2:55 pm-8:30 pm

1 stop8h 35m

$347

PhoenixLouisville

PHX - SDF

PHXSDF

Phoenix Sky Harbor Intl

Sat 9/19

6:00 am-5:39 pm

2 stops8h 39m

Louisville Intl

Tue 9/22

9:00 am-12:56 pm

1 stop6h 56m

$360

PhoenixLouisville

PHX - SDF

PHXSDF

Phoenix Sky Harbor Intl

Thu 9/24

11:52 pm-9:37 am

1 stop6h 45m

Louisville Intl

Sun 9/27

5:15 am-8:54 am

1 stop6h 39m

$397

PhoenixLouisville

PHX - SDF

PHXSDF

Phoenix Sky Harbor Intl

Wed 9/16

11:32 am-10:36 pm

1 stop8h 04m

Louisville Intl

Fri 9/18

5:15 am-3:16 pm

2 stops13h 01m

$402

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/25

Showing 1-10 of 20 resultsSorted by cheapest first
1
2

Best time to book a flight from Mesa to Louisville

Have a flexible travel schedule? Discover the best time to fly to Louisville from Mesa with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Mesa to Louisville

What is the cheapest time of day to fly from MS9 to SDF?

Find hourly flight availability from Mesa to Louisville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated June 29, 2026.

It’s optimal to fly from Mesa to Louisville in the evening. By choosing this option you can save up to 27% on the cost of your flight, compared to a flight in the afternoon.

How much does it cost to fly round-trip from Mesa to Louisville?

Reviews of airlines servicing Louisville

Get insights into the airlines that provide service to Louisville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Louisville. Reviews last updated June 29, 2026.
Peruse reviews from past customers who have flown with Southwest,Delta, andUnited Airlines from Mesa to Louisville to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.

Boarding

8.1

Food

7.0

Crew

8.6

Overall

7.9

Entertainment

7.5

Comfort

8.0

Reviews

1 / 20
8.0
Excellent

Libby,Jun 2026

TUS - LAS

One delay in a 2 layover flight=a good trip. The crew was great.

Boarding

8.1

Food

7.0

Crew

8.6

Overall

7.9

Entertainment

7.5

Comfort

8.0

Reviews

1 / 20
8.0
Excellent

Libby,Jun 2026

TUS - LAS

One delay in a 2 layover flight=a good trip. The crew was great.

Boarding

8.1

Food

7.0

Crew

8.6

Overall

7.9

Entertainment

7.5

Comfort

8.0

Reviews

1 / 20
8.0
Excellent

Libby,Jun 2026

TUS - LAS

One delay in a 2 layover flight=a good trip. The crew was great.

Boarding

8.1

Food

7.0

Crew

8.6

Overall

7.9

Entertainment

7.5

Comfort

8.0

Reviews

1 / 20
8.0
Excellent

Libby,Jun 2026

TUS - LAS

One delay in a 2 layover flight=a good trip. The crew was great.

Boarding

8.1

Food

7.0

Crew

8.6

Overall

7.9

Entertainment

7.5

Comfort

8.0

Reviews

1 / 20
8.0
Excellent

Libby,Jun 2026

TUS - LAS

One delay in a 2 layover flight=a good trip. The crew was great.

Boarding

8.1

Food

7.0

Crew

8.6

Overall

7.9

Entertainment

7.5

Comfort

8.0

Reviews

1 / 20
8.0
Excellent

Libby,Jun 2026

TUS - LAS

One delay in a 2 layover flight=a good trip. The crew was great.

Related info for your journey

Find useful and relevant information for your journey from Mesa to Louisville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • What airport do you fly into for flights to Louisville from Mesa?

    Located just 5.3 mi from the city center, Louisville Intl is the airport most travelers will use when flying to Louisville from Mesa. Booking flights from Mesa to Louisville Intl (SDF) should be relatively easy as there are 0 daily inbound flights from Mesa from 5 different airlines.

  • How long is the flight from Mesa to Louisville?

    Departing from Mesa to Louisville will take you 6h 08m. The distance from Mesa to Louisville is about 1501 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines to fly from Mesa to Louisville one-way?

    The cheapest airlines for a one-way flight from Mesa to Louisville are American Airlines ($113), Delta ($148), and United Airlines ($148).

  • What are the cheapest flights from Mesa to Louisville?

    The cheapest flight price from Mesa to Louisville is $334. On average you can expect to pay $507. The most popular route, (Phoenix Sky Harbor Intl - Louisville Intl), can usually be booked for $297.

  • Can I find deals for flights from Mesa to Louisville that include hotel bookings?

    Yes. In addition to deals on Mesa to Louisville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Mesa to Louisville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Mesa to Louisville.

  • Can I find deals for business class flights from Mesa to Louisville?

    Yes. Cheapflights offers flight deals from Mesa to Louisville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Traveling to a place near Louisville?

Book flights to Louisville if you plan to visit one of these locations
Corydon
Shepherdsville
Elizabethtown
Jeffersonville
Bardstown

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Top 5 airlines flying from Mesa to Louisville

Discover the top 5 airlines that operate flights from Mesa to Louisville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 29, 2026.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$182Average$396FlexibilityNo cancel feeOn-time69%
JetBlueCheapest$238Average$318FlexibilityNo cancel feeOn-time62%
American AirlinesCheapest$256Average$411FlexibilityNo cancel feeOn-time71%
DeltaCheapest$261Average$381FlexibilityNo cancel feeOn-timeN/A
SouthwestCheapest$270Average$490FlexibilityNo cancel feeOn-time63%

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