Louisville

$104+ Cheap flights from Mesa, AZ to Louisville (SDF)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/30. Fares are subject to change and may not be available on all flights or dates of travel.
PHX — SDF
Jun 10 — Jun 171
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Mesa to Louisville with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.
Cheapflights Tip: The best prices from Mesa to Louisville Intl are usually found in November or August, booked 79 days in advance, depart on a Saturday or Tuesday and return on a Wednesday

Cheap flight deals from Mesa to Louisville

Cheapest flights from Mesa to Louisville
Explore the most affordable flight options available from Mesa to Louisville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 11, 2026.

This American Airlines deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/2312:50 am
PHX
-
SDF
1 stop6h 27m
American Airlines
Wed 5/271:21 pm
SDF
-
PHX
1 stop6h 41m
American Airlines
Deal found 5/10$237
This Southwest deal was found by Cheapflights users on 5/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/276:00 am
PHX
-
SDF
1 stop5h 45m
Southwest
Fri 5/292:40 pm
SDF
-
PHX
2 stops8h 10m
Southwest
Deal found 5/9$242
This American Airlines deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/2612:35 am
PHX
-
SDF
1 stop7h 01m
American Airlines
Sat 5/307:45 pm
SDF
-
PHX
1 stop6h 48m
American Airlines
Deal found 5/7$247
This Southwest deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/2711:55 pm
PHX
-
SDF
1 stop7h 20m
Southwest
Sat 7/44:20 pm
SDF
-
PHX
Nonstop3h 40m
Southwest
Deal found 5/6$268
This Southwest deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/267:05 am
PHX
-
SDF
1 stop7h 05m
Southwest
Wed 5/276:40 pm
SDF
-
PHX
1 stop6h 00m
Southwest
Deal found 5/7$288
This Delta deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/2011:59 pm
PHX
-
SDF
1 stop7h 30m
Delta
Fri 7/246:49 am
SDF
-
PHX
1 stop6h 54m
Delta
Deal found 5/8$297
This Southwest deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/27:40 am
PHX
-
SDF
1 stop7h 55m
Southwest
Wed 6/37:00 am
SDF
-
PHX
2 stops8h 25m
Southwest
Deal found 5/8$302
This Southwest deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/210:10 pm
PHX
-
SDF
2 stops8h 40m
Southwest
Fri 6/56:05 pm
SDF
-
PHX
2 stops7h 35m
Southwest
Deal found 5/6$307
This Southwest deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/811:05 pm
PHX
-
SDF
1 stop8h 05m
Southwest
Mon 6/153:00 pm
SDF
-
PHX
2 stops10h 40m
Southwest
Deal found 5/8$308

Find flight deals from Mesa to Louisville

Keep the following information in mind while searching for Mesa to Louisville flight deals. Data was last updated May 11, 2026.

Round-trip from

$237
(American Airlines)

One-way from

$104
(Southwest)

Popular in

July

Cheapest in

November

Average price

$449
From Mesa to Louisville Intl
One-way flight from Mesa to Louisville Intl
Highest demand for flights based on searches. 4% potential increase in price ($20 potential increase over avg. RT price).
Cheapest flight prices on average. 1% potential price decrease ($8 potential savings vs. average RT price).
Average for round-trip flights in May 2026

Cheapflights Fare Finder

 
Customize your flight search to find flights from Mesa to Louisville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 11, 2026.
Use the filters below to find and compare flights from Mesa to Louisville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip
Quickest round-trip

PhoenixLouisville

PHX - SDF

PHXSDF

Phoenix Sky Harbor Intl

Mon 6/1

11:55 pm-9:50 am

1 stop6h 55m

Louisville Intl

Thu 6/4

6:05 pm-8:55 pm

1 stop5h 50m

$297

PhoenixLouisville

PHX - SDF

PHXSDF

Phoenix Sky Harbor Intl

Wed 6/10

6:50 am-5:19 pm

1 stop7h 29m

Louisville Intl

Sat 6/13

8:10 am-12:15 pm

1 stop7h 05m

$297

PhoenixLouisville

PHX - SDF

PHXSDF

Phoenix Sky Harbor Intl

Thu 6/11

2:50 pm-12:25 am

1 stop6h 35m

Louisville Intl

Mon 6/15

5:05 pm-11:35 pm

1 stop9h 30m

$297

PhoenixLouisville

PHX - SDF

PHXSDF

Phoenix Sky Harbor Intl

Sun 5/31

12:59 am-11:59 am

1 stop8h 00m

Louisville Intl

Thu 6/4

8:10 am-2:26 pm

1 stop9h 16m

$297

PhoenixLouisville

PHX - SDF

PHXSDF

Phoenix Sky Harbor Intl

Sun 7/5

2:40 pm-11:55 pm

1 stop6h 15m

Louisville Intl

Fri 7/10

3:00 pm-8:30 pm

1 stop8h 30m

$297

PhoenixLouisville

PHX - SDF

PHXSDF

Phoenix Sky Harbor Intl

Sat 7/18

10:57 pm-9:54 am

1 stop7h 57m

Louisville Intl

Sun 7/26

6:45 pm-10:39 pm

1 stop6h 54m

$297

PhoenixLouisville

PHX - SDF

PHXSDF

Phoenix Sky Harbor Intl

Thu 8/6

8:10 am-6:30 pm

1 stop7h 20m

Louisville Intl

Wed 8/12

7:05 am-11:00 am

2 stops6h 55m

$302

PhoenixLouisville

PHX - SDF

PHXSDF

Phoenix Sky Harbor Intl

Sat 6/27

12:05 pm-9:40 pm

2 stops6h 35m

Louisville Intl

Sat 7/4

8:50 am-1:15 pm

2 stops7h 25m

$332

PhoenixLouisville

PHX - SDF

PHXSDF

Phoenix Sky Harbor Intl

Thu 5/14

12:30 pm-9:59 pm

1 stop6h 29m

Louisville Intl

Thu 5/28

7:52 pm-11:37 pm

1 stop6h 45m

$342

PhoenixLouisville

PHX - SDF

PHXSDF

Phoenix Sky Harbor Intl

Sun 5/24

6:00 am-2:28 pm

1 stop5h 28m

Louisville Intl

Wed 5/27

6:00 am-3:10 pm

2 stops12h 10m

$393

Flights are sorted by cheapest round-trip flights first.

Deals found on 5/6

Showing 1-10 of 21 resultsSorted by cheapest first
1
2
3

Best time to book a flight from Mesa to Louisville

Have a flexible travel schedule? Discover the best time to fly to Louisville from Mesa with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Mesa to Louisville

What is the cheapest time of day to fly from MS9 to SDF?

Find hourly flight availability from Mesa to Louisville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated May 11, 2026.

It’s optimal to fly from Mesa to Louisville in the evening. By choosing this option you can save up to 18% on the cost of your flight, compared to a flight at noon.

How much does it cost to fly round-trip from Mesa to Louisville?

Reviews of airlines servicing Louisville

Get insights into the airlines that provide service to Louisville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Louisville. Reviews last updated May 11, 2026.
Peruse reviews from past customers who have flown with Southwest,Delta, andUnited Airlines from Mesa to Louisville to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.

Food

7.0

Overall

8.0

Comfort

8.0

Boarding

8.1

Entertainment

7.5

Crew

8.6

Reviews

1 / 20
2.0
Mediocre

Dominic,Mar 2026

MCO - SMF

I had to try and sleep on the floor of the Austin airport. I spent 12 hours there. The airline policies were so poor, that a near violent argument broke out between the people in front of me and the flight attendants - making for a super stressful situation at 30,000 feet. Garbage airline choice by Kayak Garbage idea to book a flight with a layover. Next time I will pay for a quality booking myself, and somehow force the company to reimburse it.

Food

7.0

Overall

8.0

Comfort

8.0

Boarding

8.1

Entertainment

7.5

Crew

8.6

Reviews

1 / 20
2.0
Mediocre

Dominic,Mar 2026

MCO - SMF

I had to try and sleep on the floor of the Austin airport. I spent 12 hours there. The airline policies were so poor, that a near violent argument broke out between the people in front of me and the flight attendants - making for a super stressful situation at 30,000 feet. Garbage airline choice by Kayak Garbage idea to book a flight with a layover. Next time I will pay for a quality booking myself, and somehow force the company to reimburse it.

Food

7.0

Overall

8.0

Comfort

8.0

Boarding

8.1

Entertainment

7.5

Crew

8.6

Reviews

1 / 20
2.0
Mediocre

Dominic,Mar 2026

MCO - SMF

I had to try and sleep on the floor of the Austin airport. I spent 12 hours there. The airline policies were so poor, that a near violent argument broke out between the people in front of me and the flight attendants - making for a super stressful situation at 30,000 feet. Garbage airline choice by Kayak Garbage idea to book a flight with a layover. Next time I will pay for a quality booking myself, and somehow force the company to reimburse it.

Food

7.0

Overall

8.0

Comfort

8.0

Boarding

8.1

Entertainment

7.5

Crew

8.6

Reviews

1 / 20
2.0
Mediocre

Dominic,Mar 2026

MCO - SMF

I had to try and sleep on the floor of the Austin airport. I spent 12 hours there. The airline policies were so poor, that a near violent argument broke out between the people in front of me and the flight attendants - making for a super stressful situation at 30,000 feet. Garbage airline choice by Kayak Garbage idea to book a flight with a layover. Next time I will pay for a quality booking myself, and somehow force the company to reimburse it.

Food

7.0

Overall

8.0

Comfort

8.0

Boarding

8.1

Entertainment

7.5

Crew

8.6

Reviews

1 / 20
2.0
Mediocre

Dominic,Mar 2026

MCO - SMF

I had to try and sleep on the floor of the Austin airport. I spent 12 hours there. The airline policies were so poor, that a near violent argument broke out between the people in front of me and the flight attendants - making for a super stressful situation at 30,000 feet. Garbage airline choice by Kayak Garbage idea to book a flight with a layover. Next time I will pay for a quality booking myself, and somehow force the company to reimburse it.

Related info for your journey

Find useful and relevant information for your journey from Mesa to Louisville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • What airport do you fly into for flights to Louisville from Mesa?

    Located just 5.3 mi from the city center, Louisville Intl is the airport most travelers will use when flying to Louisville from Mesa. Booking flights from Mesa to Louisville Intl (SDF) should be relatively easy as there are 0 daily inbound flights from Mesa from 4 different airlines.

  • How long is the flight from Mesa to Louisville?

    Departing from Mesa to Louisville will take you 6h 55m. The distance from Mesa to Louisville is about 1501 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines to fly from Mesa to Louisville one-way?

    The cheapest airlines for a one-way flight from Mesa to Louisville are American Airlines ($113), Delta ($148), and United Airlines ($148).

  • What are the cheapest flights from Mesa to Louisville?

    The cheapest flight price from Mesa to Louisville is $246. On average you can expect to pay $462. The most popular route, (Phoenix Sky Harbor Intl - Louisville Intl), can usually be booked for $267.

  • Can I find deals for flights from Mesa to Louisville that include hotel bookings?

    Yes. In addition to deals on Mesa to Louisville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Mesa to Louisville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Mesa to Louisville.

  • Can I find deals for business class flights from Mesa to Louisville?

    Yes. Cheapflights offers flight deals from Mesa to Louisville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Traveling to a place near Louisville?

Book flights to Louisville if you plan to visit one of these locations
Shepherdsville
Elizabethtown
Corydon
Jeffersonville
Bardstown

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Top 4 airlines flying from Mesa to Louisville

Discover the top 4 airlines that operate flights from Mesa to Louisville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 11, 2026.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$182Average$397FlexibilityNo cancel feeOn-time69%
DeltaCheapest$256Average$388FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$256Average$447FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$274Average$509FlexibilityNo cancel feeOn-time63%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.