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$143+ Cheap flights from Iowa to Louisville (SDF)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/26. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — SDF
Nov 28 — Dec 51
Fri 11/28
Fri 12/5
1 adult, Economy
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Cheap flight deals from Iowa to Louisville

Keep the following information in mind while searching for Iowa to Louisville flight deals. Data was last updated October 29, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$229
(Delta)

One-way from

$143
(Kiwi.com)

Popular in

December

Cheapest in

August

Average price

$360
Provider with most accurate pricing for Des Moines-Louisville Intl flight deals.
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Provider most trusted by Cheapflights users for Des Moines-Louisville Intl flights.
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From Iowa to Louisville Intl
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One-way flight from Iowa to Louisville Intl
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Highest demand for flights based on searches. 9% potential increase in price ($38 potential increase over avg. RT price).
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Cheapest flight prices on average. 2% potential price decrease ($9 potential savings vs. average RT price).
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Average for round-trip flights in October 2025
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Find flight deals from Iowa to Louisville

Cheapest flights from Iowa to Louisville
Explore the most affordable flight options available from Iowa to Louisville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 29, 2025.

This American Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/115:35 pmMLI - SDF
1 stop5h 47mAmerican Airlines
Mon 12/154:27 pmSDF - MLI
1 stop7h 32mAmerican Airlines
Deal found 10/28$229
This United Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/115:20 pmMLI - SDF
1 stop4h 09mUnited Airlines
Sat 11/159:00 amSDF - MLI
1 stop3h 50mUnited Airlines
Deal found 10/27$239
This American Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/115:46 amMLI - SDF
1 stop6h 26mAmerican Airlines
Sat 11/153:38 pmSDF - MLI
2 stops9h 17mAmerican Airlines
Deal found 10/27$244
This American Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/114:07 pmDSM - SDF
1 stop7h 15mAmerican Airlines
Thu 12/187:24 pmSDF - DSM
1 stop6h 13mAmerican Airlines
Deal found 10/27$250
This American Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/124:58 pmCID - SDF
1 stop4h 57mAmerican Airlines
Sun 11/166:00 amSDF - CID
1 stop5h 59mAmerican Airlines
Deal found 10/28$259
This United Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/125:20 pmMLI - SDF
1 stop4h 09mUnited Airlines
Sun 11/167:00 amSDF - MLI
1 stop5h 50mUnited Airlines
Deal found 10/28$259
This Delta deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1212:29 pmCID - SDF
2 stops10h 37mDelta
Sun 11/166:35 amSDF - CID
1 stop6h 13mDelta
Deal found 10/28$264
This American Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/126:18 amMLI - SDF
2 stops10h 50mAmerican Airlines
Sun 11/166:00 amSDF - MLI
1 stop4h 20mAmerican Airlines
Deal found 10/28$264
This Delta deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/76:38 pmCID - SDF
1 stop4h 23mDelta
Sun 11/96:16 pmSDF - CID
1 stop5h 22mDelta
Deal found 10/27$279
This Kiwi.com deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/16:53 pmDSM - SDF
1 stop22h 00mMultiple Airlines
Thu 12/411:55 amSDF - DSM
1 stop11h 26mMultiple Airlines
Deal found 10/28$284
This Delta deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/265:55 pmOMA - SDF
1 stop5h 11mDelta
Wed 12/310:44 amSDF - OMA
1 stop7h 31mDelta
Deal found 10/26$287
This United Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/3010:50 amMLI - SDF
1 stop5h 26mUnited Airlines
Sun 11/27:00 amSDF - MLI
1 stop4h 15mUnited Airlines
Deal found 10/28$299

Cheapflights Fare Finder

 
Customize your flight search to find flights from Iowa to Louisville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 29, 2025.
Use the filters below to find and compare flights from Iowa to Louisville that are best for you.

Fly from

Iowa

Fly to

Louisville

Route

Depart

Return

Price

MolineLouisville

MLI - SDF

MLISDF

Moline Quad-City

Tue 11/11

5:20 pm-10:29 pm

1 stop4h 09m

Louisville Intl

Sat 11/15

9:00 am-11:50 am

1 stop3h 50m

$239

MolineLouisville

MLI - SDF

MLISDF

Moline Quad-City

Tue 11/11

5:46 am-1:12 pm

1 stop6h 26m

Louisville Intl

Sat 11/15

3:38 pm-11:55 pm

2 stops9h 17m

$244

Des MoinesLouisville

DSM - SDF

DSMSDF

Des Moines

Thu 12/11

4:07 pm-12:22 am

1 stop7h 15m

Louisville Intl

Thu 12/18

7:24 pm-12:37 am

1 stop6h 13m

$250

Des MoinesLouisville

DSM - SDF

DSMSDF

Des Moines

Tue 3/3

10:15 am-5:42 pm

1 stop6h 27m

Louisville Intl

Wed 3/4

6:36 am-10:22 am

1 stop4h 46m

$251

Des MoinesLouisville

DSM - SDF

DSMSDF

Des Moines

Mon 1/5

3:27 pm-11:30 pm

1 stop7h 03m

Louisville Intl

Wed 1/7

7:40 am-3:15 pm

1 stop8h 35m

$251

MolineLouisville

MLI - SDF

MLISDF

Moline Quad-City

Wed 11/12

5:20 pm-10:29 pm

1 stop4h 09m

Louisville Intl

Sun 11/16

7:00 am-11:50 am

1 stop5h 50m

$259

Cedar RapidsLouisville

CID - SDF

CIDSDF

Cedar Rapids

Wed 11/12

4:58 pm-10:55 pm

1 stop4h 57m

Louisville Intl

Sun 11/16

6:00 am-10:59 am

1 stop5h 59m

$259

Des MoinesLouisville

DSM - SDF

DSMSDF

Des Moines

Mon 1/5

5:45 am-3:55 pm

2 stops9h 10m

Louisville Intl

Wed 1/7

12:50 pm-9:10 pm

2 stops9h 20m

$261

OmahaLouisville

OMA - SDF

OMASDF

Omaha Eppley Airfield

Sat 1/17

7:00 am-3:42 pm

2 stops7h 42m

Louisville Intl

Tue 1/20

7:13 pm-10:56 pm

1 stop4h 43m

$262

Cedar RapidsLouisville

CID - SDF

CIDSDF

Cedar Rapids

Wed 11/12

12:29 pm-12:06 am

2 stops10h 37m

Louisville Intl

Sun 11/16

6:35 am-11:48 am

1 stop6h 13m

$264

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/28

Showing 1-10 of 48 results
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Best time to book a flight from Iowa to Louisville

Have a flexible travel schedule? Discover the best time to fly to Louisville from Iowa with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Iowa to Louisville

What is the cheapest month to book a flight from Iowa to Louisville?

Currently, August is the cheapest month in which you can book a flight from Iowa to Louisville (average of $118). Flying from Iowa to Louisville in May is currently the most expensive (average of $264). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from Iowa to Louisville?

Related info for your journey

Find useful and relevant information for your journey from Iowa to Louisville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Louisville from Iowa?

    Louisville Intl (SDF), located 5.3 mi from the city center, is the airport you fly into when you book flights from Iowa to Louisville.

  • How long is the flight from Iowa to Louisville?

    For as low as $239, United Airlines can have you in Louisville from Iowa in 4h 09m. The distance from Iowa to Louisville is about 339 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines to fly from Iowa to Louisville one-way?

    The cheapest airline one-way is Allegiant Air, with whom users have recently found tickets for as low as $143. However, be on the lookout for offers from United Airlines and American Airlines, as they are both options that can get you from Iowa to Louisville for a low price.

  • What are the most popular routes from Iowa to Louisville?

    When deciding which route to take from Iowa to Louisville consider Cedar Rapids - Louisville Intl, Des Moines - Louisville Intl or Omaha Eppley Airfield - Louisville Intl as they are the most popular.

  • Can I find deals for flights from Iowa to Louisville that include hotel bookings?

    Yes. In addition to deals on Iowa to Louisville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Iowa to Louisville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Iowa to Louisville.

  • Can I find deals for business class flights from Iowa to Louisville?

    Yes. Cheapflights offers flight deals from Iowa to Louisville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Iowa to Louisville?

    Currently, August is the cheapest month in which you can book a flight from Iowa to Louisville (average of $118). Flying from Iowa to Louisville in May is currently the most expensive (average of $264). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Louisville?

Book flights to Louisville if you plan to visit one of these locations
Shepherdsville
Jeffersonville
Elizabethtown
Corydon
Bardstown

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Top 3 airlines flying from Iowa to Louisville

Discover the top 3 airlines that operate flights from Iowa to Louisville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 29, 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$148Average$491FlexibilityNo cancel feeOn-time69%
DeltaCheapest$196Average$268FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$228Average$341FlexibilityNo cancel feeOn-time71%

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