HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Louisiana

$55+ Cheap flights from Missouri to Louisiana

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/15. Fares are subject to change and may not be available on all flights or dates of travel.
STL — MSY
Nov 29 — Dec 61
Sat 11/29
Sat 12/6
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Missouri to Louisiana with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Missouri to Louisiana

Keep the following information in mind while searching for Missouri to Louisiana flight deals. Data was last updated October 30, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$127
(Priceline)

One-way from

$55
(Priceline)

Popular in

May

Cheapest in

November

Average price

$401

Good round-trip deal

$327 or less

Good one-way deal

$148 or less
Provider with most accurate pricing for Lambert-St Louis-New Orleans Louis Armstrong flight deals.
Search Deals
Provider most trusted by Cheapflights users for Lambert-St Louis-New Orleans Louis Armstrong flights.
Search Deals
From Missouri to Louisiana
Search Deals
One-way flight from Missouri to Louisiana
Search Deals
Highest demand for flights based on searches. 6% potential increase in price ($25 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($8 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in October 2025
Search Deals
Price to beat on a round-trip flight from Missouri to Louisiana.
Search Deals
Price to beat on a one-way flight from Missouri to Louisiana.
Search Deals

Find flight deals from Missouri to Louisiana

Cheapest flights from Missouri to Louisiana
Explore the most affordable flight options available from Missouri to Louisiana. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 30, 2025.

This Priceline deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/510:42 amSTL - MSY
1 stop5h 45mFrontier
Mon 12/81:52 pmMSY - STL
1 stop8h 41mFrontier
Deal found 10/30$127
This Mytrip deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/43:30 pmSTL - MSY
1 stop21h 27mFrontier
Sun 12/71:19 pmMSY - STL
1 stop20h 55mFrontier
Deal found 10/30$137
This Mytrip deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/37:43 pmSTL - MSY
1 stop16h 41mFrontier
Fri 12/51:52 pmMSY - STL
1 stop8h 41mFrontier
Deal found 10/30$150
This Frontier deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/43:30 pmSTL - MSY
1 stop21h 27mFrontier
Mon 12/81:52 pmMSY - STL
1 stop8h 41mFrontier
Deal found 10/29$151
This Mytrip deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/48:09 pmMCI - MSY
1 stop16h 15mFrontier
Sun 12/71:19 pmMSY - MCI
1 stop6h 31mFrontier
Deal found 10/28$152
This Priceline deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/113:47 pmMCI - MSY
1 stop7h 03mMultiple Airlines
Mon 12/151:53 pmMSY - MCI
1 stop5h 57mMultiple Airlines
Deal found 10/28$170
This Kiwi.com deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/510:42 amSTL - MSY
1 stop5h 45mFrontier
Sun 12/75:12 pmMSY - STL
1 stop16h 40mFrontier
Deal found 10/29$176
This Kiwi.com deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/412:04 pmSTL - MSY
1 stop8h 34mMultiple Airlines
Mon 12/85:22 pmMSY - STL
2 stops29h 11mMultiple Airlines
Deal found 10/28$184
This Priceline deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/43:47 pmMCI - MSY
1 stop7h 03mMultiple Airlines
Sun 12/71:19 pmMSY - MCI
1 stop6h 31mMultiple Airlines
Deal found 10/28$187
This Kiwi.com deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/512:13 pmMCI - MSY
1 stop8h 25mMultiple Airlines
Sun 12/75:12 pmMSY - MCI
1 stop18h 39mMultiple Airlines
Deal found 10/28$190
This Kiwi.com deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/37:31 pmMCI - MSY
1 stop12h 51mMultiple Airlines
Sun 12/75:12 pmMSY - MCI
1 stop18h 39mMultiple Airlines
Deal found 10/28$197
This Kiwi.com deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/118:09 pmMCI - MSY
1 stop16h 15mFrontier
Sun 12/145:12 pmMSY - MCI
1 stop18h 39mFrontier
Deal found 10/28$199

Cheapflights Fare Finder

 
Customize your flight search to find flights from Missouri to Louisiana that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 30, 2025.
Use the filters below to find and compare flights from Missouri to Louisiana that are best for you.

Fly from

Missouri

Fly to

Louisiana

Route

Depart

Return

Price

St. LouisNew Orleans

STL - MSY

STLMSY

Lambert-St Louis

Thu 1/8

10:42 am-5:01 pm

1 stop6h 19m

New Orleans Louis Armstrong

Mon 1/12

1:58 pm-10:33 pm

1 stop8h 35m

$110

St. LouisNew Orleans

STL - MSY

STLMSY

Lambert-St Louis

Sun 11/9

6:21 pm-8:35 am

1 stop14h 14m

New Orleans Louis Armstrong

Wed 11/12

8:29 am-10:12 am

2 stops25h 43m

$238

St. LouisNew Orleans

STL - MSY

STLMSY

Lambert-St Louis

Tue 12/16

9:30 am-4:32 pm

1 stop7h 02m

New Orleans Louis Armstrong

Tue 12/23

7:42 am-12:21 pm

1 stop4h 39m

$239

St. LouisNew Orleans

STL - MSY

STLMSY

Lambert-St Louis

Wed 12/31

3:20 pm-9:20 pm

1 stop6h 00m

New Orleans Louis Armstrong

Mon 1/5

5:10 am-9:55 am

1 stop4h 45m

$239

St. LouisNew Orleans

STL - MSY

STLMSY

Lambert-St Louis

Mon 12/22

7:00 am-11:56 am

1 stop4h 56m

New Orleans Louis Armstrong

Thu 1/1

5:26 pm-11:38 pm

1 stop6h 12m

$239

St. LouisShreveport

STL - SHV

STLSHV

Lambert-St Louis

Wed 11/19

5:17 pm-11:28 pm

1 stop6h 11m

Shreveport

Sat 11/22

4:59 pm-9:58 pm

1 stop4h 59m

$244

SpringfieldNew Orleans

SGF - MSY

SGFMSY

Springfield-Branson

Mon 1/19

3:00 pm-9:51 pm

1 stop6h 51m

New Orleans Louis Armstrong

Sat 1/24

2:13 pm-6:12 pm

1 stop3h 59m

$249

SpringfieldNew Orleans

SGF - MSY

SGFMSY

Springfield-Branson

Fri 2/20

11:35 am-6:04 pm

1 stop6h 29m

New Orleans Louis Armstrong

Mon 2/23

3:06 pm-9:13 pm

1 stop6h 07m

$249

SpringfieldNew Orleans

SGF - MSY

SGFMSY

Springfield-Branson

Sun 1/25

10:50 am-3:40 pm

1 stop4h 50m

New Orleans Louis Armstrong

Sun 2/1

6:23 am-12:15 pm

1 stop5h 52m

$249

SpringfieldNew Orleans

SGF - MSY

SGFMSY

Springfield-Branson

Fri 11/28

6:15 am-1:09 pm

1 stop6h 54m

New Orleans Louis Armstrong

Tue 12/2

9:05 am-2:04 pm

1 stop4h 59m

$249

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/30

Showing 1-10 of 60 results
1
2
3
...
6

Best time to book a flight from Missouri to Louisiana

Have a flexible travel schedule? Discover the best time to fly to Louisiana from Missouri with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Missouri to Louisiana

What is the cheapest month to book a flight from Missouri to Louisiana?

Currently, October is the cheapest month in which you can book a flight from Missouri to Louisiana (average of $94). Flying from Missouri to Louisiana in December is currently the most expensive (average of $238). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MO to LA?

Find hourly flight availability from Missouri to Louisiana. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated October 30, 2025.

A simple way to save on the total cost of your ticket is to fly from Missouri to Louisiana in the afternoon. If you’re flexible enough to do this you can expect to save up to 9% on your trip compared to booking a flight at noon.

What is the cheapest day to fly from Missouri to Louisiana?

Use this chart to determine the cheapest time to fly round-trip from Missouri to Louisiana. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their Missouri to Louisiana flight should consider departing on Wednesday evenings when fares are most often at their lowest. Saturday at noon flights should be avoided if possible as fares are typically the most expensive at this time.

Reviews of airlines servicing Louisiana

Get insights into the airlines that provide service to Louisiana. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Louisiana. Reviews last updated October 30, 2025.
Get a feel of what it's like to fly with Southwest, Delta, and United Airlines from Missouri to Louisiana by reading reviews from past customers. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,243 reviews

Comfort

8.0

Boarding

8.1

Food

7.0

Overall

8.0

Entertainment

7.5

Crew

8.6

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Southwest
8.0
Very good
4,243 reviews
Southwest
8.0
Very good
4,243 reviews

Comfort

8.0

Boarding

8.1

Food

7.0

Overall

8.0

Entertainment

7.5

Crew

8.6

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Delta
7.9
Good
7,998 reviews
Southwest
8.0
Very good
4,243 reviews

Comfort

8.0

Boarding

8.1

Food

7.0

Overall

8.0

Entertainment

7.5

Crew

8.6

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
United Airlines
7.4
Good
8,998 reviews
Southwest
8.0
Very good
4,243 reviews

Comfort

8.0

Boarding

8.1

Food

7.0

Overall

8.0

Entertainment

7.5

Crew

8.6

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
American Airlines
7.2
Good
11,035 reviews
Southwest
8.0
Very good
4,243 reviews

Comfort

8.0

Boarding

8.1

Food

7.0

Overall

8.0

Entertainment

7.5

Crew

8.6

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Spirit Airlines
6.3
Okay
8,116 reviews
Southwest
8.0
Very good
4,243 reviews

Comfort

8.0

Boarding

8.1

Food

7.0

Overall

8.0

Entertainment

7.5

Crew

8.6

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines

Related info for your journey

Find useful and relevant information for your journey from Missouri to Louisiana. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How popular is this Missouri to Louisiana flight route?

    This flight path from Missouri to Louisiana was viewed by 3 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

  • How long is the flight from Missouri to Louisiana?

    Airlines like Frontier, Delta, and Southwest fly from Missouri to Louisiana in about 6h. The time it takes to get you to your destination can typically vary by up to 1h 02m. Missouri and Louisiana are separated by a distance of 605 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines to fly from Missouri to Louisiana one-way?

    One-way options have recently been found by users for as low as $97 on Spirit Airlines. Other airlines that offer cheap prices include Delta from $120 and United Airlines from $120 one-way.

  • Can I find deals for flights from Missouri to Louisiana that include hotel bookings?

    Yes. In addition to deals on Missouri to Louisiana flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Missouri to Louisiana?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missouri to Louisiana.

  • Can I find deals for business class flights from Missouri to Louisiana?

    Yes. Cheapflights offers flight deals from Missouri to Louisiana by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Missouri to Louisiana?

    Currently, October is the cheapest month in which you can book a flight from Missouri to Louisiana (average of $94). Flying from Missouri to Louisiana in December is currently the most expensive (average of $238). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Missouri to Louisiana

See prices for flight routes from nearby airports that may be better suited for you.
John F Kennedy Intl to Fort Lauderdale flights
Los Angeles to John F Kennedy Intl flights
John F Kennedy Intl to Miami flights
Newark to Miami flights
John F Kennedy Intl to Orlando flights
John F Kennedy Intl to Los Angeles flights
Newark to Fort Lauderdale flights
Dallas/Fort Worth to John F Kennedy Intl flights
LaGuardia to Fort Lauderdale flights
LaGuardia to Miami flights
John F Kennedy Intl to Dallas/Fort Worth flights
Dallas/Fort Worth to LaGuardia flights
LaGuardia to Dallas/Fort Worth flights
Newark to Dallas/Fort Worth flights
Dallas/Fort Worth to Las Vegas flights
John F Kennedy Intl to Las Vegas flights
San Francisco to John F Kennedy Intl flights
O'Hare Intl to John F Kennedy Intl flights
Newark to Los Angeles flights
John F Kennedy Intl to O'Hare Intl flights
Dallas/Fort Worth to Newark flights
John F Kennedy Intl to San Francisco flights
Los Angeles to Dallas/Fort Worth flights
John F Kennedy Intl to West Palm Beach flights
Los Angeles to Newark flights
San Francisco to Los Angeles flights
Seattle to Los Angeles flights
Newark to Orlando flights
San Francisco to Newark flights
Newark to Las Vegas flights
Los Angeles to San Francisco flights
Fort Lauderdale to Newark flights
Los Angeles to Seattle flights
Atlanta to John F Kennedy Intl flights
Los Angeles to Honolulu flights
Los Angeles to LaGuardia flights
San Francisco to Las Vegas flights
John F Kennedy Intl to Tampa flights
LaGuardia to Hobby flights
John F Kennedy Intl to Atlanta flights
Newark to San Francisco flights
Hobby to Newark flights
Fort Lauderdale to John F Kennedy Intl flights
Dulles Intl to Dallas/Fort Worth flights
LaGuardia to Orlando flights
Dallas/Fort Worth to Los Angeles flights
LaGuardia to Tampa flights
Newark to West Palm Beach flights
Newark to Tampa flights
Hobby to LaGuardia flights

Top 6 airlines flying from Missouri to Louisiana

Discover the top 6 airlines that operate flights from Missouri to Louisiana. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 30, 2025.
AirlineCheapestAverageFlexibilityOn-time
FrontierCheapest$127Average$238FlexibilityNo cancel feeOn-time62%
DeltaCheapest$127Average$317FlexibilityNo cancel feeOn-timeN/A
Spirit AirlinesCheapest$158Average$290FlexibilityNo cancel feeOn-time65%
American AirlinesCheapest$158Average$376FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$194Average$425FlexibilityNo cancel feeOn-time69%
SouthwestCheapest$240Average$397FlexibilityNo cancel feeOn-time63%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.