$383+ Cheap flights from Panama City, FL to Lexington (ECP - LEX)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/30. Fares are subject to change and may not be available on all flights or dates of travel.
ECP — LEX
Oct 17 — Oct 241
Round-trip
1 adult, Economy
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Find cheap flights from Panama City to Lexington with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Panama City to Lexington
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Cheapest flights from Panama City to LexingtonExplore the most affordable flight options available from Panama City to Lexington. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 17, 2026.
Explore the most affordable flight options available from Panama City to Lexington. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 17, 2026.
This American Airlines deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/146:42 pm -
1 stop4h 15m
Mon 10/195:00 am -
1 stop6h 28m
Deal found 9/12![American Airlines logo]()
$422
This United Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1111:30 am -
2 stops11h 24m
Sat 11/149:00 am -
1 stop5h 09m
Deal found 9/15![United Airlines logo]()
$424
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/138:05 am -
1 stop4h 48m
Tue 10/206:00 am -
1 stop6h 38m
Deal found 9/14![American Airlines logo]()
$432
This United Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/292:08 pm -
1 stop5h 20m
Mon 10/56:00 am -
1 stop8h 03m
Deal found 9/13![United Airlines logo]()
$434
This Delta deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/147:12 am -
1 stop3h 46m
Tue 10/2011:04 am -
1 stop3h 51m
Deal found 9/14![Delta logo]()
$437
This United Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/3011:41 am -
2 stops11h 14m
Mon 10/58:50 am -
1 stop5h 13m
Deal found 9/14![United Airlines logo]()
$439
This Delta deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/146:00 am -
1 stop3h 09m
Sat 10/175:59 pm -
1 stop6h 19m
Deal found 9/14![Delta logo]()
$441
This United Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/3011:41 am -
2 stops11h 14m
Tue 10/66:00 am -
2 stops9h 03m
Deal found 9/13![United Airlines logo]()
$444
This Delta deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/149:19 am -
1 stop4h 30m
Fri 10/237:59 pm -
1 stop4h 19m
Deal found 9/14![Delta logo]()
$447
This Delta deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/156:20 pm -
1 stop4h 38m
Sat 10/175:59 pm -
1 stop6h 19m
Deal found 9/14![Delta logo]()
$451
Best flights from Panama City to LexingtonDiscover carefully curated flight deals from Panama City to Lexington that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 17, 2026.
Discover carefully curated flight deals from Panama City to Lexington that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 17, 2026.
This United Airlines deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1111:30 am -
2 stops11h 24m
Sat 11/149:00 am -
1 stop5h 09m
Deal found 9/12![United Airlines logo]()
$424
This Delta deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/136:00 am -
1 stop4h 58m
Tue 10/205:59 pm -
1 stop6h 19m
Deal found 9/12![Delta logo]()
$437
This United Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/292:08 pm -
1 stop5h 20m
Mon 10/56:00 am -
2 stops11h 13m
Deal found 9/13![United Airlines logo]()
$439
This Delta deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/166:20 pm -
1 stop4h 38m
Mon 10/191:04 pm -
1 stop5h 31m
Deal found 9/12![Delta logo]()
$457
This United Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/3011:41 am -
2 stops11h 14m
Mon 10/56:00 am -
2 stops11h 13m
Deal found 9/14![United Airlines logo]()
$444
This United Airlines deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/146:20 am -
2 stops13h 08m
Sat 10/176:00 am -
2 stops11h 13m
Deal found 9/12![United Airlines logo]()
$474
Last-minute flights from Panama City to LexingtonDiscover last-minute flight deals from Panama City to Lexington. Data last updated September 17, 2026 and is based on user searches.
Discover last-minute flight deals from Panama City to Lexington. Data last updated September 17, 2026 and is based on user searches.
This United Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/292:08 pm -
1 stop5h 20m
Mon 10/56:00 am -
1 stop8h 03m
Deal found 9/13![United Airlines logo]()
$434
This United Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/3011:41 am -
2 stops11h 14m
Mon 10/58:50 am -
1 stop5h 13m
Deal found 9/14![United Airlines logo]()
$439
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/138:05 am -
1 stop4h 48m
Tue 10/206:00 am -
1 stop6h 38m
Deal found 9/14![American Airlines logo]()
$432
This American Airlines deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/146:42 pm -
1 stop4h 15m
Mon 10/195:00 am -
1 stop6h 28m
Deal found 9/12![American Airlines logo]()
$422
This Delta deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/147:12 am -
1 stop3h 46m
Tue 10/2011:04 am -
1 stop3h 51m
Deal found 9/14![Delta logo]()
$437
This Delta deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/146:00 am -
1 stop3h 09m
Sat 10/175:59 pm -
1 stop6h 19m
Deal found 9/14![Delta logo]()
$441
This Delta deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/149:19 am -
1 stop4h 30m
Fri 10/237:59 pm -
1 stop4h 19m
Deal found 9/14![Delta logo]()
$447
This Delta deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/156:20 pm -
1 stop4h 38m
Sat 10/175:59 pm -
1 stop6h 19m
Deal found 9/14![Delta logo]()
$451
This Delta deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/156:20 pm -
1 stop4h 38m
Fri 10/237:59 pm -
1 stop4h 19m
Deal found 9/14![Delta logo]()
$457
One-way flights from Panama City to LexingtonSearch for one-way flight options from Panama City to Lexington. Find affordable one-way fares based on user searches. Data last updated September 17, 2026.
Search for one-way flight options from Panama City to Lexington. Find affordable one-way fares based on user searches. Data last updated September 17, 2026.
This Delta deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/307:35 am -
1 stop3h 09m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/12![Delta logo]()
$383
This United Airlines deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/3011:41 am -
2 stops11h 14m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/12![United Airlines logo]()
$384
This American Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/57:15 am -
2 stops8h 14m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/16![American Airlines logo]()
$388
This Delta deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/46:00 am -
1 stop4h 44m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/14![Delta logo]()
$440
This Delta deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/251:46 pm -
1 stop4h 56m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/12![Delta logo]()
$473
This American Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/31:32 pm -
2 stops9h 19m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/13![American Airlines logo]()
$487
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/46:43 pm -
1 stop4h 16m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/14![American Airlines logo]()
$542
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/811:04 am -
2 stops10h 26m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/15![American Airlines logo]()
$547
This United Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/44:57 pm -
2 stops15h 31m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/16![United Airlines logo]()
$702
Find flight deals from Panama City to Lexington
Discover tips and strategies to find the most affordable flight options for your journey from Panama City (ECP) to Lexington (LEX). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 17, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $387 (American Airlines) |
One-way from | $383 (Delta) |
Popular in | July |
Cheapest in | February |
Average price | $436 |
Cheapflights Fare Finder
Customize your flight search to find flights from Panama City to Lexington that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 17, 2026.
Use the filters below to find and compare flights from Panama City to Lexington that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Quickest round-trip
Panama CityLexington
ECP Panama City NW Florida Beaches - LEX Lexington Blue Grass
ECPLEX
Panama City NW Florida Beaches
Wed 9/30
7:35 am-11:44 am
1 stop3h 09m
Lexington Blue Grass
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$383
Panama CityLexington
ECP Panama City NW Florida Beaches - LEX Lexington Blue Grass
ECPLEX
Panama City NW Florida Beaches
Thu 10/8
6:42 pm-11:57 pm
1 stop4h 15m
Lexington Blue Grass
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$383
Panama CityLexington
ECP Panama City NW Florida Beaches - LEX Lexington Blue Grass
ECPLEX
Panama City NW Florida Beaches
Sat 10/3
7:35 am-12:16 pm
1 stop3h 41m
Lexington Blue Grass
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$383
Panama CityLexington
ECP Panama City NW Florida Beaches - LEX Lexington Blue Grass
ECPLEX
Panama City NW Florida Beaches
Wed 9/30
11:41 am-11:55 pm
2 stops11h 14m
Lexington Blue Grass
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$384
Panama CityLexington
ECP Panama City NW Florida Beaches - LEX Lexington Blue Grass
ECPLEX
Panama City NW Florida Beaches
Mon 10/5
7:15 am-4:29 pm
2 stops8h 14m
Lexington Blue Grass
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$388
Panama CityLexington
ECP Panama City NW Florida Beaches - LEX Lexington Blue Grass
ECPLEX
Panama City NW Florida Beaches
Wed 11/11
11:30 am-11:54 pm
2 stops11h 24m
Lexington Blue Grass
Sat 11/14
9:00 am-1:09 pm
1 stop5h 09m
$424
Panama CityLexington
ECP Panama City NW Florida Beaches - LEX Lexington Blue Grass
ECPLEX
Panama City NW Florida Beaches
Tue 10/13
6:00 am-11:58 am
1 stop4h 58m
Lexington Blue Grass
Tue 10/20
5:59 pm-11:18 pm
1 stop6h 19m
$437
Panama CityLexington
ECP Panama City NW Florida Beaches - LEX Lexington Blue Grass
ECPLEX
Panama City NW Florida Beaches
Tue 9/29
2:08 pm-8:28 pm
1 stop5h 20m
Lexington Blue Grass
Mon 10/5
6:00 am-4:13 pm
2 stops11h 13m
$439
Panama CityLexington
ECP Panama City NW Florida Beaches - LEX Lexington Blue Grass
ECPLEX
Panama City NW Florida Beaches
Sun 10/4
6:00 am-11:44 am
1 stop4h 44m
Lexington Blue Grass
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$440
Panama CityLexington
ECP Panama City NW Florida Beaches - LEX Lexington Blue Grass
ECPLEX
Panama City NW Florida Beaches
Wed 9/30
11:41 am-11:55 pm
2 stops11h 14m
Lexington Blue Grass
Mon 10/5
6:00 am-4:13 pm
2 stops11h 13m
$444
Showing 1-10 of 15 resultsSorted by cheapest first
Compare providers for flights from Panama City to Lexington
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Panama City to Lexington in September.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy1 star | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Panama City, Florida-Lexington flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Panama City, Florida-Lexington flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Panama City, Florida-Lexington flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Panama City, Florida-Lexington flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Panama City, Florida-Lexington flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Panama City to Lexington
Have a flexible travel schedule? Discover the best time to fly to Lexington from Panama City with our price prediction graph.
ECP-LEX
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Reviews of airlines servicing Lexington
Get insights into the airlines that provide service to Lexington. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Lexington. Reviews last updated September 17, 2026.
Get a feel of what it's like to fly with Delta from Panama City to Lexington by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Crew
8.5
Entertainment
7.8
Food
7.2
Boarding
8.1
Comfort
7.8
Overall
7.8
Reviews
1 / 20
8.0
ExcellentJorge,Aug 2026
TPA - ATL
Crew
8.5
Entertainment
7.8
Food
7.2
Boarding
8.1
Comfort
7.8
Overall
7.8
Reviews
1 / 20
8.0
ExcellentJorge,Aug 2026
TPA - ATL
Related info for your journey
Find useful and relevant information for your journey from Panama City to Lexington. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Lexington?
Book flights to Lexington if you plan to visit one of these locationsSomerset
Richmond
Danville
Berea
Frankfort
Georgetown
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Other flights to Lexington
Explore flights to Lexington departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on September 17, 2026.
Panama City and Lexington flights
Browse other Panama City and Lexington flight options. Last updated on September 17, 2026.
Other flights from Panama City
Browse through other flights departing from Panama City. Flights are based on user searches made on Cheapflights and were last updated on September 17, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top airline flying from Panama City to Lexington
Discover the top airline that operate flights from Panama City to Lexington. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 17, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$293 | Average$428 | FlexibilityNo cancel fee | On-timeN/A |