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Lexington

$264+ Cheap flights from Panama City, FL to Lexington (ECP - LEX)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/10. Fares are subject to change and may not be available on all flights or dates of travel.
ECP — LEX
Feb 26 — Mar 51
Thu 2/26
Thu 3/5
1 adult, Economy
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Cheap flight deals from Panama City to Lexington

Cheapest flights from Panama City to Lexington
Explore the most affordable flight options available from Panama City to Lexington. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 27, 2026.

This Delta deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/106:00 am
ECP
-
LEX
1 stop4h 54m
Delta
Mon 3/167:55 pm
LEX
-
ECP
1 stop4h 09m
Delta
Deal found 1/26$269
This American Airlines deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/1312:38 pm
ECP
-
LEX
1 stop8h 24m
American Airlines
Tue 2/171:58 pm
LEX
-
ECP
1 stop8h 24m
American Airlines
Deal found 1/26$274
This Delta deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/96:00 am
ECP
-
LEX
1 stop4h 54m
Delta
Tue 3/172:20 pm
LEX
-
ECP
1 stop6h 27m
Delta
Deal found 1/26$294
This American Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/2510:20 am
ECP
-
LEX
2 stops12h 06m
American Airlines
Sun 3/15:50 pm
LEX
-
ECP
1 stop6h 59m
American Airlines
Deal found 1/27$299
This Delta deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/97:05 am
ECP
-
LEX
1 stop3h 49m
Delta
Sun 3/156:00 am
LEX
-
ECP
1 stop3h 40m
Delta
Deal found 1/26$319
This Delta deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/197:05 am
ECP
-
LEX
1 stop3h 49m
Delta
Sun 3/226:00 am
LEX
-
ECP
1 stop3h 40m
Delta
Deal found 1/26$324
This American Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/292:33 pm
ECP
-
LEX
2 stops7h 47m
American Airlines
Sat 9/58:17 pm
LEX
-
ECP
1 stop4h 24m
American Airlines
Deal found 1/27$334
This Delta deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/106:00 am
ECP
-
LEX
2 stops10h 07m
Delta
Tue 3/174:14 pm
LEX
-
ECP
1 stop4h 33m
Delta
Deal found 1/26$343
This American Airlines deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/108:20 am
ECP
-
LEX
2 stops12h 37m
American Airlines
Wed 3/1810:27 am
LEX
-
ECP
1 stop4h 57m
American Airlines
Deal found 1/26$344
This American Airlines deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/108:20 am
ECP
-
LEX
2 stops12h 37m
American Airlines
Tue 3/176:40 am
LEX
-
ECP
2 stops7h 50m
American Airlines
Deal found 1/26$357
This Delta deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/106:00 am
ECP
-
LEX
2 stops10h 07m
Delta
Sun 3/156:00 am
LEX
-
ECP
1 stop3h 40m
Delta
Deal found 1/26$368

Find flight deals from Panama City to Lexington

Discover tips and strategies to find the most affordable flight options for your journey from Panama City (ECP) to Lexington (LEX). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated January 27, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$269
(Delta)

One-way from

$264
(American Airlines)

Popular in

January

Cheapest in

June

Average price

$513
Provider with most accurate pricing for Panama City NW Florida Beaches-Lexington Blue Grass flight deals.
Search Deals
Provider most trusted by Cheapflights users for Panama City NW Florida Beaches-Lexington Blue Grass flights.
Search Deals
From Panama City NW Florida Beaches to Lexington Blue Grass
Search Deals
One-way flight from Panama City NW Florida Beaches to Lexington Blue Grass
Search Deals
Highest demand for flights based on searches. 14% potential increase in price ($57 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 5% potential price decrease ($19 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in January 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Panama City to Lexington that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 27, 2026.
Use the filters below to find and compare flights from Panama City to Lexington that are best for you.

Fly from

Panama City

Fly to

Lexington

Route

Depart

Return

Price

Panama CityLexington

ECP - LEX

ECPLEX

Panama City NW Florida Beaches

Tue 3/10

8:25 am-1:39 pm

1 stop4h 14m

Lexington Blue Grass

Mon 3/16

7:55 pm-11:04 pm

1 stop4h 09m

$269

Panama CityLexington

ECP - LEX

ECPLEX

Panama City NW Florida Beaches

Tue 3/10

6:00 am-11:54 am

1 stop4h 54m

Lexington Blue Grass

Tue 3/17

2:20 pm-7:47 pm

1 stop6h 27m

$269

Panama CityLexington

ECP - LEX

ECPLEX

Panama City NW Florida Beaches

Thu 3/26

7:05 am-11:54 am

1 stop3h 49m

Lexington Blue Grass

Sun 3/29

7:55 pm-11:04 pm

1 stop4h 09m

$269

Panama CityLexington

ECP - LEX

ECPLEX

Panama City NW Florida Beaches

Mon 3/9

6:00 am-11:54 am

1 stop4h 54m

Lexington Blue Grass

Mon 3/16

7:55 pm-11:04 pm

1 stop4h 09m

$269

Panama CityLexington

ECP - LEX

ECPLEX

Panama City NW Florida Beaches

Thu 3/12

6:00 am-11:54 am

1 stop4h 54m

Lexington Blue Grass

Tue 3/17

4:14 pm-7:47 pm

1 stop4h 33m

$269

Panama CityLexington

ECP - LEX

ECPLEX

Panama City NW Florida Beaches

Wed 3/11

7:05 am-1:39 pm

1 stop5h 34m

Lexington Blue Grass

Tue 3/17

4:14 pm-7:47 pm

1 stop4h 33m

$269

Panama CityLexington

ECP - LEX

ECPLEX

Panama City NW Florida Beaches

Wed 2/25

6:00 am-11:50 am

1 stop4h 50m

Lexington Blue Grass

Sun 3/1

6:00 am-8:41 am

1 stop3h 41m

$269

Panama CityLexington

ECP - LEX

ECPLEX

Panama City NW Florida Beaches

Mon 3/9

6:00 am-11:54 am

1 stop4h 54m

Lexington Blue Grass

Sun 3/15

4:14 pm-9:22 pm

1 stop6h 08m

$294

Panama CityLexington

ECP - LEX

ECPLEX

Panama City NW Florida Beaches

Tue 2/10

6:03 pm-11:15 pm

1 stop4h 12m

$264

Panama CityLexington

ECP - LEX

ECPLEX

Panama City NW Florida Beaches

Sun 2/15

6:00 am-1:25 pm

1 stop6h 25m

$264

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/26

Showing 1-10 of 17 results
1
2

Compare providers for flights from Panama City to Lexington

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Panama City to Lexington in January.
ProviderPrice AccuracyTrust Score*
FlightHubPrice Accuracy3 starsTrust Score*3 stars
ExpediaPrice Accuracy1 starTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Panama City, Florida-Lexington flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Panama City, Florida-Lexington flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Panama City, Florida-Lexington flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Panama City, Florida-Lexington flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Panama City, Florida-Lexington flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Panama City to Lexington

Have a flexible travel schedule? Discover the best time to fly to Lexington from Panama City with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Panama City to Lexington

What is the cheapest month to book a flight from Panama City, Florida to Lexington?

Currently, March is the cheapest month in which you can book a flight from Panama City, Florida to Lexington (average of $84). Flying from Panama City, Florida to Lexington in June is currently the most expensive (average of $189). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Lexington

Get insights into the airlines that provide service to Lexington. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Lexington. Reviews last updated January 27, 2026.
Get a feel of what it's like to fly with Delta and American Airlines from Panama City to Lexington by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,118 reviews

Crew

8.5

Food

7.2

Entertainment

7.8

Overall

7.9

Boarding

8.1

Comfort

7.9

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.
Delta
7.9
Good
8,118 reviews
Delta
7.9
Good
8,118 reviews

Crew

8.5

Food

7.2

Entertainment

7.8

Overall

7.9

Boarding

8.1

Comfort

7.9

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.
American Airlines
7.2
Good
11,197 reviews
Delta
7.9
Good
8,118 reviews

Crew

8.5

Food

7.2

Entertainment

7.8

Overall

7.9

Boarding

8.1

Comfort

7.9

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.

Related info for your journey

Find useful and relevant information for your journey from Panama City to Lexington. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Panama City, Florida to Lexington?

    Departing from Panama City, Florida to Lexington will take you 4h 14m. Airlines will cover a distance of 535 mi.

  • What are the cheapest airlines flying from Panama City, Florida to Lexington round-trip?

    Cheapflights users have booked flights from Panama City, Florida to Lexington round-trip from $248. Another airline that can offer you cheap pricing is Delta. American Airlines is 28% cheaper than the average price of flights available within the next 90 days to this destination.

  • Can I find deals for flights from Panama City to Lexington that include hotel bookings?

    Yes. In addition to deals on Panama City to Lexington flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Panama City to Lexington?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama City to Lexington.

  • Can I find deals for business class flights from Panama City to Lexington?

    Yes. Cheapflights offers flight deals from Panama City to Lexington by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Panama City, Florida to Lexington?

    Currently, March is the cheapest month in which you can book a flight from Panama City, Florida to Lexington (average of $84). Flying from Panama City, Florida to Lexington in June is currently the most expensive (average of $189). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Lexington?

Book flights to Lexington if you plan to visit one of these locations
Somerset
Berea
Georgetown
Frankfort

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Top 2 airlines flying from Panama City to Lexington

Discover the top 2 airlines that operate flights from Panama City to Lexington. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 27, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$248Average$325FlexibilityNo cancel feeOn-time71%
DeltaCheapest$248Average$318FlexibilityNo cancel feeOn-timeN/A

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