HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Lexington

$126+ Cheap flights from Missouri to Lexington (LEX)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/6. Fares are subject to change and may not be available on all flights or dates of travel.
STL — LEX
Nov 30 — Dec 71
Sun 11/30
Sun 12/7
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Missouri to Lexington with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Find flight deals from Missouri to Lexington

Cheapest flights from Missouri to Lexington
Explore the most affordable flight options available from Missouri to Lexington. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 31, 2025.

This Delta deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/47:05 amSTL - LEX
1 stop6h 51mDelta
Mon 12/85:15 pmLEX - STL
1 stop4h 47mDelta
Deal found 10/30$229
This Delta deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/65:50 amMCI - LEX
1 stop5h 35mDelta
Sun 12/77:59 pmLEX - MCI
1 stop4h 48mDelta
Deal found 10/29$249
This American Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/611:40 amMCI - LEX
2 stops7h 04mAmerican Airlines
Sun 12/76:10 pmLEX - MCI
1 stop6h 53mAmerican Airlines
Deal found 10/29$254
This American Airlines deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/144:28 pmSGF - LEX
1 stop5h 48mAmerican Airlines
Tue 11/187:55 amLEX - SGF
1 stop5h 25mAmerican Airlines
Deal found 10/30$259
This American Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/136:00 amSTL - LEX
1 stop3h 33mAmerican Airlines
Mon 11/177:18 pmLEX - STL
1 stop4h 49mAmerican Airlines
Deal found 10/29$259
This United Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/2211:26 amSGF - LEX
1 stop6h 40mUnited Airlines
Wed 11/265:45 pmLEX - SGF
1 stop5h 28mUnited Airlines
Deal found 10/29$264
This American Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/255:00 amSTL - LEX
1 stop4h 47mAmerican Airlines
Fri 11/286:58 pmLEX - STL
1 stop6h 04mAmerican Airlines
Deal found 10/28$274
This Delta deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/146:38 pmMCI - LEX
1 stop4h 26mDelta
Tue 11/185:40 pmLEX - MCI
1 stop7h 10mDelta
Deal found 10/30$279
This American Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/307:00 amSGF - LEX
1 stop5h 53mAmerican Airlines
Thu 11/65:00 amLEX - SGF
1 stop6h 35mAmerican Airlines
Deal found 10/29$309
This Delta deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/41:30 pmSTL - LEX
1 stop4h 44mDelta
Tue 11/115:40 pmLEX - STL
1 stop5h 18mDelta
Deal found 10/30$309
This American Airlines deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/43:38 pmSTL - LEX
2 stops6h 38mAmerican Airlines
Tue 11/112:11 pmLEX - STL
1 stop6h 19mAmerican Airlines
Deal found 10/30$314
This American Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/215:15 amMCI - LEX
1 stop7h 14mAmerican Airlines
Mon 12/18:10 pmLEX - MCI
1 stop4h 52mAmerican Airlines
Deal found 10/29$339

Cheap flight deals from Missouri to Lexington

Keep the following information in mind while searching for Missouri to Lexington flight deals. Data was last updated October 31, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$229
(Delta)

One-way from

$126
(Kiwi.com)

Popular in

April

Cheapest in

January
Provider with most accurate pricing for Lambert-St Louis-Lexington Blue Grass flight deals.
Search Deals
Provider most trusted by Cheapflights users for Lambert-St Louis-Lexington Blue Grass flights.
Search Deals
From Missouri to Lexington Blue Grass
Search Deals
One-way flight from Missouri to Lexington Blue Grass
Search Deals
Highest demand for flights based on searches. 22% potential increase in price ($91 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 6% potential price decrease ($20 potential savings vs. average RT price).
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Missouri to Lexington that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 31, 2025.
Use the filters below to find and compare flights from Missouri to Lexington that are best for you.

Fly from

Missouri

Fly to

Lexington

Route

Depart

Return

Price

St. LouisLexington

STL - LEX

STLLEX

Lambert-St Louis

Thu 12/4

7:05 am-2:56 pm

1 stop6h 51m

Lexington Blue Grass

Mon 12/8

5:15 pm-9:02 pm

1 stop4h 47m

$229

St. LouisLexington

STL - LEX

STLLEX

Lambert-St Louis

Fri 12/5

7:02 pm-12:08 am

1 stop4h 06m

Lexington Blue Grass

Sun 12/7

7:59 pm-11:42 pm

1 stop4h 43m

$229

Kansas CityLexington

MCI - LEX

MCILEX

Kansas City

Sat 12/6

5:50 am-12:25 pm

1 stop5h 35m

Lexington Blue Grass

Sun 12/7

7:59 pm-11:47 pm

1 stop4h 48m

$249

Kansas CityLexington

MCI - LEX

MCILEX

Kansas City

Wed 1/7

11:25 am-7:13 pm

1 stop6h 48m

Lexington Blue Grass

Sat 1/10

8:10 am-2:56 pm

1 stop7h 46m

$249

SpringfieldLexington

SGF - LEX

SGFLEX

Springfield-Branson

Fri 11/14

4:28 pm-11:16 pm

1 stop5h 48m

Lexington Blue Grass

Tue 11/18

7:55 am-12:20 pm

1 stop5h 25m

$259

St. LouisLexington

STL - LEX

STLLEX

Lambert-St Louis

Thu 11/13

6:00 am-10:33 am

1 stop3h 33m

Lexington Blue Grass

Mon 11/17

7:18 pm-11:07 pm

1 stop4h 49m

$259

SpringfieldLexington

SGF - LEX

SGFLEX

Springfield-Branson

Sat 11/22

11:26 am-7:06 pm

1 stop6h 40m

Lexington Blue Grass

Wed 11/26

5:45 pm-10:13 pm

1 stop5h 28m

$264

St. LouisLexington

STL - LEX

STLLEX

Lambert-St Louis

Tue 11/4

1:30 pm-7:14 pm

1 stop4h 44m

Lexington Blue Grass

Tue 11/11

5:40 pm-9:58 pm

1 stop5h 18m

$309

St. LouisLexington

STL - LEX

STLLEX

Lambert-St Louis

Tue 11/4

3:38 pm-11:16 pm

2 stops6h 38m

Lexington Blue Grass

Tue 11/11

2:11 pm-7:30 pm

1 stop6h 19m

$314

Kansas CityLexington

MCI - LEX

MCILEX

Kansas City

Wed 1/7

5:48 am-3:37 pm

2 stops8h 49m

Lexington Blue Grass

Sat 1/10

6:00 am-2:30 pm

2 stops9h 30m

$320

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/30

Showing 1-10 of 38 results
1
2
3
4

Best time to book a flight from Missouri to Lexington

Have a flexible travel schedule? Discover the best time to fly to Lexington from Missouri with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Missouri to Lexington

What is the cheapest month to book a flight from Missouri to Lexington?

Currently, December is the cheapest month in which you can book a flight from Missouri to Lexington (average of $114). Flying from Missouri to Lexington in March is currently the most expensive (average of $249). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MO to LEX?

Find hourly flight availability from Missouri to Lexington. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated October 31, 2025.

It’s typically best to fly out from Missouri to Lexington at noon. Doing so could potentially save you 17% on the flight price compared to flying in the afternoon, which is usually more expensive.

Related info for your journey

Find useful and relevant information for your journey from Missouri to Lexington. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Lexington from Missouri?

    Lexington Blue Grass (LEX) is the airport you will fly into if you book a flight from Missouri to Lexington. It is only a 5.6 mi journey from Blue Grass (LEX) to Lexington’s city center.

  • How long is the flight from Missouri to Lexington?

    A quick flight from Missouri to Lexington can take about 5h 48m. Delta provides one of the quickest options available for as low as $259. The distance from Missouri to Lexington is about 483 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the most popular routes from Missouri to Lexington?

    When deciding which route to take from Missouri to Lexington consider Kansas City - Lexington Blue Grass, Lambert-St Louis - Lexington Blue Grass or Springfield-Branson - Lexington Blue Grass as they are the most popular.

  • Can I find deals for flights from Missouri to Lexington that include hotel bookings?

    Yes. In addition to deals on Missouri to Lexington flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Missouri to Lexington?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missouri to Lexington.

  • Can I find deals for business class flights from Missouri to Lexington?

    Yes. Cheapflights offers flight deals from Missouri to Lexington by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Missouri to Lexington?

    Currently, December is the cheapest month in which you can book a flight from Missouri to Lexington (average of $114). Flying from Missouri to Lexington in March is currently the most expensive (average of $249). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Lexington?

Book flights to Lexington if you plan to visit one of these locations
Georgetown
Berea
Frankfort

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Missouri to Lexington

See prices for flight routes from nearby airports that may be better suited for you.
John F Kennedy Intl to Nashville flights
LaGuardia to Nashville flights
Newark to Nashville flights
Los Angeles to Nashville flights
O'Hare Intl to Nashville flights
John F Kennedy Intl to Cincinnati flights
Reagan-National to Nashville flights
Boston to Nashville flights
LaGuardia to Cincinnati flights
Dallas/Fort Worth to Nashville flights
Dulles Intl to Nashville flights
Philadelphia to Nashville flights
Baltimore to Nashville flights
Seattle to Nashville flights
Denver to Nashville flights
Hobby to Nashville flights
Newark to Cincinnati flights
Minneapolis to Nashville flights
San Francisco to Nashville flights
Santa Ana to Nashville flights
Ontario to Nashville flights
Denver to Cincinnati flights
Dallas/Fort Worth to Cincinnati flights
Orlando to Nashville flights
Raleigh to Nashville flights
Fort Lauderdale to Nashville flights
Boston to Cincinnati flights
George Bush Intcntl to Nashville flights
Tampa to Nashville flights
LaGuardia to Knoxville flights
Detroit to Nashville flights
Charlotte to Nashville flights
Salt Lake City to Nashville flights
Newark to Louisville flights
O'Hare Intl to Cincinnati flights
LaGuardia to Louisville flights
San Diego to Nashville flights
John F Kennedy Intl to Knoxville flights
Austin to Nashville flights
Atlanta to Cincinnati flights
Tampa to Cincinnati flights
O'Hare Intl to Knoxville flights
Burbank to Nashville flights
Sky Harbor Intl to Nashville flights
Baltimore to Cincinnati flights
Hartford to Nashville flights
Midway to Nashville flights
Los Angeles to Cincinnati flights
Miami to Nashville flights
George Bush Intcntl to Knoxville flights

Top 3 airlines flying from Missouri to Lexington

Discover the top 3 airlines that operate flights from Missouri to Lexington. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 31, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$228Average$320FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$228Average$398FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$262Average$358FlexibilityNo cancel feeOn-time69%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.