For US-bound flights, expect two security checks at PTY, with the second at the gate. Allow extra time for this process.

Most accurate provider | eDreams 3 stars |
|---|---|
Most trusted provider | eDreams 3 stars |
Round-trip from | $546 (Kiwi.com) |
One-way from | $310 (Mytrip) |
Popular in | March |
Cheapest in | September |
Average price | $663 |
Good round-trip deal | $620 or less |
Fly from
Fly to
Route
Depart
Return
Price
Panama CityLas Vegas
PTY - LAS
PTYLAS
Panama City Tocumen Intl
Thu 1/22
6:32 pm-10:29 pm
Nonstop6h 57m
Las Vegas Harry Reid Intl
Sat 1/31
12:58 am-10:16 am
Nonstop6h 18m
Panama CityLas Vegas
PTY - LAS
PTYLAS
Panama City Tocumen Intl
Thu 2/12
3:27 pm-11:35 pm
1 stop11h 08m
Las Vegas Harry Reid Intl
Mon 2/16
4:44 pm-2:02 pm
1 stop18h 18m
Panama CityLas Vegas
PTY - LAS
PTYLAS
Panama City Tocumen Intl
Thu 1/22
4:41 pm-11:18 am
1 stop21h 37m
Las Vegas Harry Reid Intl
Sat 1/31
12:59 am-5:07 pm
1 stop13h 08m
Panama CityLas Vegas
PTY - LAS
PTYLAS
Panama City Tocumen Intl
Thu 2/12
4:41 pm-11:31 pm
1 stop9h 50m
Las Vegas Harry Reid Intl
Sun 2/15
12:59 am-2:45 pm
1 stop10h 46m
Panama CityLas Vegas
PTY - LAS
PTYLAS
Panama City Tocumen Intl
Mon 1/12
4:41 pm-4:00 pm
1 stop26h 19m
Las Vegas Harry Reid Intl
Sun 1/18
6:55 pm-5:07 pm
1 stop19h 12m
Panama CityLas Vegas
PTY - LAS
PTYLAS
Panama City Tocumen Intl
Sun 1/18
11:25 am-11:00 am
2 stops26h 35m
Panama CityLas Vegas
PTY - LAS
PTYLAS
Panama City Tocumen Intl
Tue 2/3
7:50 pm-5:53 pm
2 stops25h 03m
Panama CityLas Vegas
PTY - LAS
PTYLAS
Panama City Tocumen Intl
Thu 1/8
2:55 am-11:01 pm
3 stops23h 06m
Panama CityLas Vegas
PTY - LAS
PTYLAS
Panama City Tocumen Intl
Fri 1/9
3:00 pm-3:20 pm
1 stop27h 20m
Panama CityLas Vegas
PTY - LAS
PTYLAS
Panama City Tocumen Intl
Sun 12/21
2:55 pm-11:18 am
1 stop23h 23m
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy2 stars | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*1 star | |
| Price Accuracy2 stars | Trust Score*3 stars |
Booking 63 days in advance of your planned departure date is, on average, the best time to get cheap flights from Panama City to Las Vegas. The general trend is that the closer you book to the departure date, the more expensive your flight will be.
Currently, August is the cheapest month in which you can book a flight from Panama City to Las Vegas (average of $468). Flying from Panama City to Las Vegas in February is currently the most expensive (average of $609). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
It’s optimal to fly from Panama City to Las Vegas in the afternoon. By choosing this option you can save up to 45% on the cost of your flight, compared to a flight in the evening.
About 2% of weekly flights between Panama City and Las Vegas have experienced delays in the past year, with the average delay time being 121 minutes.
Historically, flights departing in the early afternoon are less likely to be delayed, whereas flights leaving in the evening tend to experience delays more often.
Wednesday tends to have the lowest number of delays on this route, whereas Thursday has historically faced a higher average of delays compared to other days of the week.
Over the last year, Copa Airlines have had the lowest number of delays on this route, with just 2% of flights being delayed.
Crew
Comfort
Entertainment
Overall
Boarding
Food
Reviews
Jim,Nov 2025
AVL - ATL
Crew
Comfort
Entertainment
Overall
Boarding
Food
Reviews
Jim,Nov 2025
AVL - ATL
Crew
Comfort
Entertainment
Overall
Boarding
Food
Reviews
Jim,Nov 2025
AVL - ATL
Crew
Comfort
Entertainment
Overall
Boarding
Food
Reviews
Jim,Nov 2025
AVL - ATL
Crew
Comfort
Entertainment
Overall
Boarding
Food
Reviews
Jim,Nov 2025
AVL - ATL
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$488 | Average$641 | FlexibilityNo cancel fee | On-time70% | |
| Cheapest$493 | Average$583 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$504 | Average$620 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$532 | Average$666 | FlexibilityNo cancel fee | On-time69% |