For US-bound flights, expect two security checks at PTY, with the second at the gate. Allow extra time for this process.

Most accurate provider | eDreams 3 stars |
|---|---|
Most trusted provider | eDreams 3 stars |
Round-trip from | $539 (Mytrip) |
One-way from | $335 (Kiwi.com) |
Popular in | March |
Cheapest in | September |
Average price | $663 |
Good round-trip deal | $620 or less |
Fly from
Fly to
Route
Depart
Return
Price
Panama CityLas Vegas
PTY - LAS
PTYLAS
Panama City Tocumen Intl
Mon 11/17
2:55 am-10:10 pm
2 stops22h 15m
Las Vegas Harry Reid Intl
Tue 11/25
11:29 pm-12:40 am
2 stops22h 11m
Panama CityLas Vegas
PTY - LAS
PTYLAS
Panama City Tocumen Intl
Thu 2/5
8:55 am-10:24 pm
2 stops16h 29m
Las Vegas Harry Reid Intl
Sat 2/7
12:59 am-5:07 pm
1 stop13h 08m
Panama CityLas Vegas
PTY - LAS
PTYLAS
Panama City Tocumen Intl
Thu 2/5
3:20 pm-11:35 pm
1 stop11h 15m
Las Vegas Harry Reid Intl
Sun 2/8
10:15 pm-1:55 pm
1 stop12h 40m
Panama CityLas Vegas
PTY - LAS
PTYLAS
Panama City Tocumen Intl
Thu 1/22
8:55 am-6:29 pm
1 stop12h 34m
Las Vegas Harry Reid Intl
Sat 1/31
12:59 am-2:45 pm
1 stop10h 46m
Panama CityLas Vegas
PTY - LAS
PTYLAS
Panama City Tocumen Intl
Sat 1/17
4:41 pm-9:03 am
1 stop19h 22m
Las Vegas Harry Reid Intl
Mon 1/19
12:59 am-7:38 pm
1 stop15h 39m
Panama CityLas Vegas
PTY - LAS
PTYLAS
Panama City Tocumen Intl
Mon 12/29
1:45 pm-8:49 pm
1 stop10h 04m
Panama CityLas Vegas
PTY - LAS
PTYLAS
Panama City Tocumen Intl
Sun 11/16
11:25 am-9:38 am
2 stops25h 13m
Panama CityLas Vegas
PTY - LAS
PTYLAS
Panama City Tocumen Intl
Mon 11/17
11:25 am-8:21 am
3 stops23h 56m
Panama CityLas Vegas
PTY - LAS
PTYLAS
Panama City Tocumen Intl
Fri 1/9
3:00 pm-3:20 pm
1 stop27h 20m
Panama CityLas Vegas
PTY - LAS
PTYLAS
Panama City Tocumen Intl
Sun 12/28
1:45 pm-10:39 pm
2 stops35h 54m
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy2 stars | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*1 star | |
| Price Accuracy2 stars | Trust Score*3 stars |
Booking 63 days in advance of your planned departure date is, on average, the best time to get cheap flights from Panama City to Las Vegas. The general trend is that the closer you book to the departure date, the more expensive your flight will be.
Currently, August is the cheapest month in which you can book a flight from Panama City to Las Vegas (average of $468). Flying from Panama City to Las Vegas in February is currently the most expensive (average of $609). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
It’s optimal to fly from Panama City to Las Vegas in the afternoon. By choosing this option you can save up to 45% on the cost of your flight, compared to a flight in the evening.
About 2% of weekly flights between Panama City and Las Vegas have experienced delays in the past year, with the average delay time being 121 minutes.
Historically, flights departing in the early afternoon are less likely to be delayed, whereas flights leaving in the evening tend to experience delays more often.
Wednesday tends to have the lowest number of delays on this route, whereas Thursday has historically faced a higher average of delays compared to other days of the week.
Over the last year, Copa Airlines have had the lowest number of delays on this route, with just 2% of flights being delayed.
Food
Overall
Boarding
Comfort
Crew
Entertainment
Reviews
Jim,Nov 2025
AVL - ATL
Food
Overall
Boarding
Comfort
Crew
Entertainment
Reviews
Jim,Nov 2025
AVL - ATL
Food
Overall
Boarding
Comfort
Crew
Entertainment
Reviews
Jim,Nov 2025
AVL - ATL
Food
Overall
Boarding
Comfort
Crew
Entertainment
Reviews
Jim,Nov 2025
AVL - ATL
Food
Overall
Boarding
Comfort
Crew
Entertainment
Reviews
Jim,Nov 2025
AVL - ATL
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$488 | Average$641 | FlexibilityNo cancel fee | On-time70% | |
| Cheapest$493 | Average$583 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$504 | Average$620 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$532 | Average$666 | FlexibilityNo cancel fee | On-time69% |