For US-bound flights, expect two security checks at PTY, with the second at the gate. Allow extra time for this process.

Most accurate provider | eDreams 3 stars |
|---|---|
Most trusted provider | eDreams 3 stars |
Round-trip from | $448 (Mytrip) |
One-way from | $253 (Mytrip) |
Popular in | March |
Cheapest in | September |
Average price | $631 |
Fly from
Fly to
Route
Depart
Return
Price
Panama CityLas Vegas
PTY - LAS
PTYLAS
Panama City Tocumen Intl
Thu 2/26
6:32 pm-10:29 pm
Nonstop6h 57m
Las Vegas Harry Reid Intl
Tue 3/3
12:58 am-10:16 am
Nonstop6h 18m
Panama CityLas Vegas
PTY - LAS
PTYLAS
Panama City Tocumen Intl
Tue 3/3
8:55 am-4:16 pm
1 stop10h 21m
Las Vegas Harry Reid Intl
Sat 3/7
12:36 am-1:45 pm
1 stop10h 09m
Panama CityLas Vegas
PTY - LAS
PTYLAS
Panama City Tocumen Intl
Thu 3/5
3:15 pm-11:33 pm
1 stop11h 18m
Las Vegas Harry Reid Intl
Tue 3/10
10:20 pm-1:03 pm
1 stop12h 43m
Panama CityLas Vegas
PTY - LAS
PTYLAS
Panama City Tocumen Intl
Thu 4/2
2:28 pm-11:29 pm
1 stop11h 01m
Las Vegas Harry Reid Intl
Wed 4/8
12:55 am-1:03 pm
1 stop10h 08m
Panama CityLas Vegas
PTY - LAS
PTYLAS
Panama City Tocumen Intl
Wed 4/15
7:55 am-3:49 pm
1 stop9h 54m
Las Vegas Harry Reid Intl
Sat 4/18
12:36 am-6:37 pm
1 stop16h 01m
Panama CityLas Vegas
PTY - LAS
PTYLAS
Panama City Tocumen Intl
Sat 5/2
2:20 pm-11:22 pm
1 stop11h 02m
Las Vegas Harry Reid Intl
Tue 5/5
12:35 am-12:55 pm
1 stop10h 20m
Panama CityLas Vegas
PTY - LAS
PTYLAS
Panama City Tocumen Intl
Mon 3/2
4:41 pm-11:31 pm
1 stop9h 50m
Las Vegas Harry Reid Intl
Thu 3/5
6:00 am-7:38 pm
2 stops10h 38m
Panama CityLas Vegas
PTY - LAS
PTYLAS
Panama City Tocumen Intl
Thu 3/19
7:55 am-5:57 pm
1 stop12h 02m
Las Vegas Harry Reid Intl
Mon 3/23
12:36 am-6:38 pm
1 stop16h 02m
Panama CityLas Vegas
PTY - LAS
PTYLAS
Panama City Tocumen Intl
Wed 3/4
11:35 am-8:23 pm
1 stop11h 48m
Las Vegas Harry Reid Intl
Mon 3/9
7:10 pm-1:45 pm
2 stops16h 35m
Panama CityLas Vegas
PTY - LAS
PTYLAS
Panama City Tocumen Intl
Sat 4/4
7:55 am-3:49 pm
1 stop9h 54m
Las Vegas Harry Reid Intl
Wed 4/8
6:00 am-6:37 pm
2 stops10h 37m
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy2 stars | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*1 star | |
| Price Accuracy2 stars | Trust Score*3 stars |
Booking 63 days in advance of your planned departure date is, on average, the best time to get cheap flights from Panama City to Las Vegas. The general trend is that the closer you book to the departure date, the more expensive your flight will be.
Currently, August is the cheapest month in which you can book a flight from Panama City to Las Vegas (average of $468). Flying from Panama City to Las Vegas in April is currently the most expensive (average of $589). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
When flying from Panama City to Las Vegas, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.
About 1% of weekly flights between Panama City and Las Vegas have experienced delays in the past year, with the average delay time being 128 minutes.
Historically, flights departing in the early afternoon are less likely to be delayed, whereas flights leaving in the evening tend to experience delays more often.
Wednesday tends to have the lowest number of delays on this route, whereas Thursday has historically faced a higher average of delays compared to other days of the week.
Over the last year, Copa Airlines have had the lowest number of delays on this route, with just 1% of flights being delayed.
Boarding
Entertainment
Food
Comfort
Crew
Overall
Reviews
Jim,Nov 2025
AVL - ATL
Boarding
Entertainment
Food
Comfort
Crew
Overall
Reviews
Jim,Nov 2025
AVL - ATL
Boarding
Entertainment
Food
Comfort
Crew
Overall
Reviews
Jim,Nov 2025
AVL - ATL
Boarding
Entertainment
Food
Comfort
Crew
Overall
Reviews
Jim,Nov 2025
AVL - ATL
Boarding
Entertainment
Food
Comfort
Crew
Overall
Reviews
Jim,Nov 2025
AVL - ATL
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$488 | Average$639 | FlexibilityNo cancel fee | On-time70% | |
| Cheapest$493 | Average$583 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$504 | Average$620 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$532 | Average$661 | FlexibilityNo cancel fee | On-time69% |