For US-bound flights, expect two security checks at PTY, with the second at the gate. Allow extra time for this process.

Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $463 (Kiwi.com) |
One-way from | $286 (Kiwi.com) |
Popular in | March |
Cheapest in | September |
Average price | $664 |
Good round-trip deal | $620 or less |
Fly from
Fly to
Route
Depart
Return
Price
Panama CityLas Vegas
PTY - LAS
PTYLAS
Panama City Tocumen Intl
Wed 12/17
6:24 pm-10:29 pm
Nonstop7h 05m
Las Vegas Harry Reid Intl
Thu 12/25
12:51 am-10:16 am
Nonstop6h 25m
Panama CityLas Vegas
PTY - LAS
PTYLAS
Panama City Tocumen Intl
Thu 4/2
5:33 pm-10:30 pm
Nonstop6h 57m
Las Vegas Harry Reid Intl
Wed 4/8
2:02 am-10:16 am
Nonstop6h 14m
Panama CityLas Vegas
PTY - LAS
PTYLAS
Panama City Tocumen Intl
Thu 1/22
6:32 pm-10:29 pm
Nonstop6h 57m
Las Vegas Harry Reid Intl
Sat 1/31
12:58 am-10:16 am
Nonstop6h 18m
Panama CityLas Vegas
PTY - LAS
PTYLAS
Panama City Tocumen Intl
Sat 2/14
6:32 pm-10:29 pm
Nonstop6h 57m
Las Vegas Harry Reid Intl
Sat 2/21
12:58 am-10:16 am
Nonstop6h 18m
Panama CityLas Vegas
PTY - LAS
PTYLAS
Panama City Tocumen Intl
Thu 2/12
4:41 pm-11:31 pm
1 stop9h 50m
Las Vegas Harry Reid Intl
Tue 2/17
3:25 pm-7:38 pm
1 stop25h 13m
Panama CityLas Vegas
PTY - LAS
PTYLAS
Panama City Tocumen Intl
Thu 1/22
3:27 pm-11:42 pm
1 stop11h 15m
Las Vegas Harry Reid Intl
Sun 2/1
10:10 pm-2:02 pm
1 stop12h 52m
Panama CityLas Vegas
PTY - LAS
PTYLAS
Panama City Tocumen Intl
Thu 2/5
8:55 am-11:59 pm
2 stops18h 04m
Las Vegas Harry Reid Intl
Sat 2/7
12:59 am-2:45 pm
1 stop10h 46m
Panama CityLas Vegas
PTY - LAS
PTYLAS
Panama City Tocumen Intl
Thu 1/22
8:55 am-8:15 pm
1 stop14h 20m
Las Vegas Harry Reid Intl
Sat 1/31
12:59 am-7:38 pm
1 stop15h 39m
Panama CityLas Vegas
PTY - LAS
PTYLAS
Panama City Tocumen Intl
Fri 12/26
8:55 am-11:30 pm
1 stop17h 35m
Las Vegas Harry Reid Intl
Sun 12/28
6:00 am-6:49 pm
1 stop9h 49m
Panama CityLas Vegas
PTY - LAS
PTYLAS
Panama City Tocumen Intl
Tue 3/24
7:55 am-3:32 pm
1 stop9h 37m
Las Vegas Harry Reid Intl
Tue 3/31
12:59 am-2:14 pm
1 stop11h 15m
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy2 stars | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
Booking 63 days in advance of your planned departure date is, on average, the best time to get cheap flights from Panama City to Las Vegas. The general trend is that the closer you book to the departure date, the more expensive your flight will be.
Currently, August is the cheapest month in which you can book a flight from Panama City to Las Vegas (average of $468). Flying from Panama City to Las Vegas in February is currently the most expensive (average of $609). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
It’s optimal to fly from Panama City to Las Vegas in the afternoon. By choosing this option you can save up to 46% on the cost of your flight, compared to a flight in the evening.
About 2% of weekly flights between Panama City and Las Vegas have experienced delays in the past year, with the average delay time being 121 minutes.
Historically, flights departing in the early afternoon are less likely to be delayed, whereas flights leaving in the evening tend to experience delays more often.
Wednesday tends to have the lowest number of delays on this route, whereas Thursday has historically faced a higher average of delays compared to other days of the week.
Over the last year, Copa Airlines have had the lowest number of delays on this route, with just 2% of flights being delayed.
Entertainment
Crew
Food
Boarding
Comfort
Overall
Reviews
Mary,Oct 2025
AMS - PDX
Entertainment
Crew
Food
Boarding
Comfort
Overall
Reviews
Mary,Oct 2025
AMS - PDX
Entertainment
Crew
Food
Boarding
Comfort
Overall
Reviews
Mary,Oct 2025
AMS - PDX
Entertainment
Crew
Food
Boarding
Comfort
Overall
Reviews
Mary,Oct 2025
AMS - PDX
Entertainment
Crew
Food
Boarding
Comfort
Overall
Reviews
Mary,Oct 2025
AMS - PDX
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$488 | Average$635 | FlexibilityNo cancel fee | On-time70% | |
| Cheapest$493 | Average$583 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$504 | Average$620 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$532 | Average$666 | FlexibilityNo cancel fee | On-time69% |