$453+ Cheap flights from San Diego to La Crosse (SAN - LSE)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/3. Fares are subject to change and may not be available on all flights or dates of travel.
SAN — LSE
Aug 4 — Aug 111
1 adult, Economy
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1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from San Diego to La Crosse
Discover tips and strategies to find the most affordable flight options for your journey from San Diego (SAN) to La Crosse (LSE). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated July 30, 2025.
Round-trip from | $948 (American Airlines) |
|---|---|
One-way from | $453 (American Airlines) |
Find flight deals from San Diego to La Crosse
Cheapest flights from San Diego to La CrosseExplore the most affordable flight options available from San Diego to La Crosse. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 30, 2025.
Explore the most affordable flight options available from San Diego to La Crosse. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 30, 2025.
This American Airlines deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/106:16 amSAN - LSE
1 stop6h 05mAmerican Airlines
Sat 12/132:48 pmLSE - SAN
1 stop6h 15mAmerican Airlines
Deal found 7/29![American Airlines logo]()
$534
Cheapflights Fare Finder
Customize your flight search to find flights from San Diego to La Crosse that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 30, 2025.
Use the filters below to find and compare flights from San Diego to La Crosse that are best for you.
Fly from
San Diego
Fly to
La Crosse
Route
Depart
Return
Price
San DiegoLa Crosse
SAN - LSE
SANLSE
San Diego
Sun 10/12
3:06 pm-11:26 pm
1 stop6h 20m
La Crosse
Tue 10/14
6:00 am-12:29 pm
1 stop8h 29m
$948
San DiegoLa Crosse
SAN - LSE
SANLSE
San Diego
Wed 9/3
6:15 am-5:51 pm
1 stop9h 36m
$453
Best time to book a flight from San Diego to La Crosse
Have a flexible travel schedule? Discover the best time to fly to La Crosse from San Diego with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Reviews of airlines servicing La Crosse
Get insights into the airlines that provide service to La Crosse. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to La Crosse. Reviews last updated July 30, 2025.
Peruse reviews from past customers who have flown with American Airlines from San Diego to La Crosse to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Food
6.5
Boarding
7.5
Comfort
7.2
Crew
8.0
Overall
7.2
Entertainment
6.9
Reviews
1 / 20
2.0
MediocreAndrew,May 2025
LAX - MIA
Food
6.5
Boarding
7.5
Comfort
7.2
Crew
8.0
Overall
7.2
Entertainment
6.9
Reviews
1 / 20
2.0
MediocreAndrew,May 2025
LAX - MIA
Related info for your journey
Find useful and relevant information for your journey from San Diego to La Crosse. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near La Crosse?
Book flights to La Crosse if you plan to visit one of these locationsDecorah
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Alternative routes for San Diego to La Crosse
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Top airline flying from San Diego to La Crosse
Discover the top airline that operate flights from San Diego to La Crosse. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 30, 2025.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$470 | Average$551 | FlexibilityNo cancel fee | On-time71% |