What is the cheapest airline to fly from Portland to La Crosse round-trip?

Cheapflights users have booked flights from Portland to La Crosse round-trip from $424.

In terms of precipitation, rainfall in La Crosse ranges from 1.1 - 4.3 inches per month. June is typically the wettest month, when rainfall can reach 4.3 in. January is typically the driest time to visit La Crosse when rainfall is around 1.1 in.

If weather is an important factor for your trip to La Crosse, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 73.4 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 17.6 F).

What is the cheapest time of day to fly from PDX to LSE?

When flying from Portland to La Crosse, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Most accurate provider : When it comes to deals on Portland-La Crosse flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Portland-La Crosse flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Portland-La Crosse flight searches over the past month and is updated monthly.

Most trusted provider : When it comes to deals on Portland-La Crosse flights, Cheapflights users trust Expedia the most. Expedia has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Portland-La Crosse flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Can I find deals for flights from Portland to La Crosse that include hotel bookings?

Yes. In addition to deals on Portland to La Crosse flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Portland to La Crosse?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Portland to La Crosse.

Can I find deals for business class flights from Portland to La Crosse?

Yes. Cheapflights offers flight deals from Portland to La Crosse by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$429+ Flights from Portland to La Crosse

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1. Tell us where you want to go

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Cheap flight deals from Portland to La Crosse

One-way flights from Portland to La Crosse
Search for one-way flight options from Portland to La Crosse. Find affordable one-way fares based on user searches. Data last updated January 21, 2026.

Thu 3/1911:59 pm

PDX

LSE

1 stop9h 03m

American Airlines

Deal found 1/20

$429

Sat 3/2111:59 pm

PDX

LSE

1 stop9h 03m

American Airlines

Deal found 1/20

$618

Find flight deals from Portland to La Crosse

Most accurate provider	FlightHub 3 stars
Most trusted provider	Expedia 3 stars

Provider with most accurate pricing for Portland-La Crosse flight deals.

Search Deals

Provider most trusted by Cheapflights users for Portland-La Crosse flights.

Search Deals

Fly from

Fly to

Route

Depart

Return

Price

PortlandLa Crosse

PDX - LSE

PDXLSE

Portland

Thu 3/19

11:59 pm-11:02 am

1 stop9h 03m

$429

PortlandLa Crosse

PDX - LSE

PDXLSE

Portland

Fri 3/20

11:59 pm-11:02 am

1 stop9h 03m

$429

PortlandLa Crosse

PDX - LSE

PDXLSE

Portland

Sat 3/21

11:59 pm-11:02 am

1 stop9h 03m

$618

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/20

Compare providers for flights from Portland to La Crosse

Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Portland to La Crosse in January.

Provider	Price Accuracy	Trust Score*
Expedia	Price Accuracy2 stars	Trust Score*3 stars
FlightHub	Price Accuracy3 stars	Trust Score*1 star

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

Most accurate provider: When it comes to deals on Portland-La Crosse flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Portland-La Crosse flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Portland-La Crosse flight searches over the past month and is updated monthly.
Most trusted provider: When it comes to deals on Portland-La Crosse flights, Cheapflights users trust Expedia the most. Expedia has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Portland-La Crosse flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Portland to La Crosse

Have a flexible travel schedule? Discover the best time to fly to La Crosse from Portland with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Reviews of airlines servicing La Crosse

See what other customers who have flown with American Airlines from Portland to La Crosse have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.

American Airlines

7.2

Good

11,169 reviews

Reviews

1 / 20

2.0

Mediocre

Susie,Jan 2026

CLT - TPA

This flight was delayed 3 or 4 times. We had boarded the plane, sat on plane for a good 30 minutes, then we had to board the aircraft, walk to a different gate, wait and then board another aircraft. We arrived in Tampa 4 hours later than the original booking. I feel there should have been some sort of compensation especially for the advantage members.

American Airlines

7.2

Good

11,169 reviews

American Airlines

7.2

Good

11,169 reviews

Reviews

1 / 20

2.0

Mediocre

Susie,Jan 2026

CLT - TPA

Related info for your journey

What is the cheapest airline to fly from Portland to La Crosse round-trip?
Cheapflights users have booked flights from Portland to La Crosse round-trip from $424.
Can I find deals for flights from Portland to La Crosse that include hotel bookings?
Yes. In addition to deals on Portland to La Crosse flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Portland to La Crosse?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Portland to La Crosse.
Can I find deals for business class flights from Portland to La Crosse?
Yes. Cheapflights offers flight deals from Portland to La Crosse by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Decorah

Winona

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Top airline flying from Portland to La Crosse

Airline	Cheapest	Average	Flexibility	On-time
American Airlines	Cheapest$424	Average$494	FlexibilityNo cancel fee	On-time71%

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$429+ Cheap flights from Portland to La Crosse (PDX - LSE)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/19. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Portland to La Crosse with Cheapflights

1. Tell us where you want to go

2. Select your favorite providers

3. Compare prices and book

Cheap flight deals from Portland to La Crosse

One-way flights from Portland to La CrosseSearch for one-way flight options from Portland to La Crosse. Find affordable one-way fares based on user searches. Data last updated January 21, 2026.

Search for one-way flight options from Portland to La Crosse. Find affordable one-way fares based on user searches. Data last updated January 21, 2026.

Find flight deals from Portland to La Crosse

Most accurate provider

Most trusted provider

Cheapflights Fare Finder

Use the filters below to find and compare flights from Portland to La Crosse that are best for you.

Compare providers for flights from Portland to La Crosse

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.

Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Portland to La Crosse in January.

Best time to book a flight from Portland to La Crosse

Have a flexible travel schedule? Discover the best time to fly to La Crosse from Portland with our price prediction graph.

Reviews of airlines servicing La Crosse

See what other customers who have flown with American Airlines from Portland to La Crosse have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from Portland to La Crosse. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

What is the cheapest airline to fly from Portland to La Crosse round-trip?

Can I find deals for flights from Portland to La Crosse that include hotel bookings?

How can I find direct flights from Portland to La Crosse?

Can I find deals for business class flights from Portland to La Crosse?

Traveling to a place near La Crosse?

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Portland to La Crosse

See prices for flight routes from nearby airports that may be better suited for you.

Top airline flying from Portland to La Crosse

100% Free

Book with Flexibility

Travel Smart

One-way flights from Portland to La Crosse
Search for one-way flight options from Portland to La Crosse. Find affordable one-way fares based on user searches. Data last updated January 21, 2026.