$580+ Cheap flights from Portland to La Crosse (PDX - LSE)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/12. Fares are subject to change and may not be available on all flights or dates of travel.
PDX — LSE
Dec 11 — Dec 181
Round-trip
1 adult, Economy
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Find cheap flights from Portland to La Crosse with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Portland to La Crosse
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Best
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Cheapest flights from Portland to La CrosseExplore the most affordable flight options available from Portland to La Crosse. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 11, 2026.
Explore the most affordable flight options available from Portland to La Crosse. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 11, 2026.
This American Airlines deal was found by Cheapflights users on 11/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/121:22 pm -
1 stop8h 56m
Sat 11/1412:24 pm -
1 stop9h 18m
Deal found 11/10![American Airlines logo]()
$580
This American Airlines deal was found by Cheapflights users on 11/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/121:22 pm -
1 stop8h 56m
Mon 11/1612:24 pm -
1 stop9h 23m
Deal found 11/7![American Airlines logo]()
$634
This American Airlines deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/301:46 pm -
1 stop8h 44m
Sun 1/37:05 pm -
1 stop7h 04m
Deal found 11/9![American Airlines logo]()
$683
This American Airlines deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/111:22 pm -
1 stop8h 56m
Thu 11/196:01 am -
1 stop8h 25m
Deal found 11/6![American Airlines logo]()
$700
This American Airlines deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/111:22 pm -
1 stop8h 56m
Fri 11/2012:26 pm -
1 stop10h 03m
Deal found 11/6![American Airlines logo]()
$723
This American Airlines deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/111:22 pm -
1 stop8h 56m
Mon 11/236:01 am -
1 stop8h 25m
Deal found 11/6![American Airlines logo]()
$724
This American Airlines deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/121:22 pm -
1 stop8h 56m
Thu 11/1912:26 pm -
1 stop10h 03m
Deal found 11/6![American Airlines logo]()
$754
This American Airlines deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/111:22 pm -
1 stop8h 56m
Wed 11/256:01 am -
1 stop8h 25m
Deal found 11/6![American Airlines logo]()
$761
This American Airlines deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/121:22 pm -
1 stop8h 56m
Fri 11/2012:26 pm -
1 stop10h 03m
Deal found 11/6![American Airlines logo]()
$777
Best flights from Portland to La CrosseDiscover carefully curated flight deals from Portland to La Crosse that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated November 11, 2026.
Discover carefully curated flight deals from Portland to La Crosse that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated November 11, 2026.
This American Airlines deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/31:30 pm -
1 stop9h 00m
Sun 12/612:09 pm -
1 stop9h 46m
Deal found 11/9![American Airlines logo]()
$634
This American Airlines deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/3011:59 pm -
2 stops10h 35m
Sun 1/37:05 pm -
1 stop7h 04m
Deal found 11/9![American Airlines logo]()
$689
This American Airlines deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/171:22 pm -
1 stop8h 56m
Sat 11/2112:26 pm -
2 stops13h 33m
Deal found 11/6![American Airlines logo]()
$730
This American Airlines deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/145:14 am -
2 stops11h 02m
Thu 11/1912:26 pm -
2 stops13h 50m
Deal found 11/6![American Airlines logo]()
$813
This American Airlines deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/161:22 pm -
1 stop8h 56m
Wed 11/256:01 am -
1 stop8h 25m
Deal found 11/6![American Airlines logo]()
$815
This American Airlines deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/151:22 pm -
1 stop8h 56m
Sun 11/2212:26 pm -
2 stops13h 33m
Deal found 11/6![American Airlines logo]()
$870
This American Airlines deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/151:22 pm -
1 stop8h 56m
Sat 11/216:01 am -
1 stop8h 25m
Deal found 11/6![American Airlines logo]()
$901
This American Airlines deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/171:22 pm -
1 stop8h 56m
Thu 11/1912:26 pm -
2 stops13h 33m
Deal found 11/6![American Airlines logo]()
$992
Last-minute flights from Portland to La CrosseDiscover last-minute flight deals from Portland to La Crosse. Data last updated November 11, 2026 and is based on user searches.
Discover last-minute flight deals from Portland to La Crosse. Data last updated November 11, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/111:22 pm -
1 stop8h 56m
Thu 11/196:01 am -
1 stop8h 25m
Deal found 11/6![American Airlines logo]()
$700
This American Airlines deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/111:22 pm -
1 stop8h 56m
Fri 11/2012:26 pm -
1 stop10h 03m
Deal found 11/6![American Airlines logo]()
$723
This American Airlines deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/111:22 pm -
1 stop8h 56m
Mon 11/236:01 am -
1 stop8h 25m
Deal found 11/6![American Airlines logo]()
$724
This American Airlines deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/111:22 pm -
1 stop8h 56m
Wed 11/256:01 am -
1 stop8h 25m
Deal found 11/6![American Airlines logo]()
$761
This American Airlines deal was found by Cheapflights users on 11/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/121:22 pm -
1 stop8h 56m
Sat 11/1412:24 pm -
1 stop9h 18m
Deal found 11/10![American Airlines logo]()
$580
This American Airlines deal was found by Cheapflights users on 11/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/121:22 pm -
1 stop8h 56m
Mon 11/1612:24 pm -
1 stop9h 23m
Deal found 11/7![American Airlines logo]()
$634
This American Airlines deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/121:22 pm -
1 stop8h 56m
Thu 11/1912:26 pm -
1 stop10h 03m
Deal found 11/6![American Airlines logo]()
$754
This American Airlines deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/121:22 pm -
1 stop8h 56m
Fri 11/2012:26 pm -
1 stop10h 03m
Deal found 11/6![American Airlines logo]()
$777
This American Airlines deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/301:46 pm -
1 stop8h 44m
Sun 1/37:05 pm -
1 stop7h 04m
Deal found 11/9![American Airlines logo]()
$683
One-way flights from Portland to La CrosseSearch for one-way flight options from Portland to La Crosse. Find affordable one-way fares based on user searches. Data last updated November 11, 2026.
Search for one-way flight options from Portland to La Crosse. Find affordable one-way fares based on user searches. Data last updated November 11, 2026.
This American Airlines deal was found by Cheapflights users on 11/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/291:19 pm -
1 stop9h 01m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/10![American Airlines logo]()
$645
Find flight deals from Portland to La Crosse
Discover tips and strategies to find the most affordable flight options for your journey from Portland (PDX) to La Crosse (LSE). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated November 11, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $634 (American Airlines) |
Cheapflights Fare Finder
Customize your flight search to find flights from Portland to La Crosse that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated November 11, 2026.
Use the filters below to find and compare flights from Portland to La Crosse that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
PortlandLa Crosse
PDX Portland - LSE La Crosse
PDXLSE
Portland
Thu 12/3
1:30 pm-12:30 am
1 stop9h 00m
La Crosse
Sun 12/6
12:09 pm-7:55 pm
1 stop9h 46m
$634
Quickest round-trip
PortlandLa Crosse
PDX Portland - LSE La Crosse
PDXLSE
Portland
Sun 11/29
1:19 pm-12:20 am
1 stop9h 01m
La Crosse
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$645
PortlandLa Crosse
PDX Portland - LSE La Crosse
PDXLSE
Portland
Wed 12/30
11:59 pm-12:34 pm
2 stops10h 35m
La Crosse
Sun 1/3
7:05 pm-12:09 am
1 stop7h 04m
$689
PortlandLa Crosse
PDX Portland - LSE La Crosse
PDXLSE
Portland
Tue 11/17
1:22 pm-12:18 am
1 stop8h 56m
La Crosse
Sat 11/21
12:26 pm-11:59 pm
2 stops13h 33m
$730
PortlandLa Crosse
PDX Portland - LSE La Crosse
PDXLSE
Portland
Sat 11/14
5:14 am-6:16 pm
2 stops11h 02m
La Crosse
Thu 11/19
12:26 pm-12:16 am
2 stops13h 50m
$813
PortlandLa Crosse
PDX Portland - LSE La Crosse
PDXLSE
Portland
Mon 11/16
1:22 pm-12:18 am
1 stop8h 56m
La Crosse
Wed 11/25
6:01 am-12:26 pm
1 stop8h 25m
$815
PortlandLa Crosse
PDX Portland - LSE La Crosse
PDXLSE
Portland
Sun 11/15
1:22 pm-12:18 am
1 stop8h 56m
La Crosse
Sun 11/22
12:26 pm-11:59 pm
2 stops13h 33m
$870
PortlandLa Crosse
PDX Portland - LSE La Crosse
PDXLSE
Portland
Sun 11/15
1:22 pm-12:18 am
1 stop8h 56m
La Crosse
Sat 11/21
6:01 am-12:26 pm
1 stop8h 25m
$901
PortlandLa Crosse
PDX Portland - LSE La Crosse
PDXLSE
Portland
Tue 11/17
1:22 pm-12:18 am
1 stop8h 56m
La Crosse
Thu 11/19
12:26 pm-11:59 pm
2 stops13h 33m
$992
Sorted by cheapest first
Compare providers for flights from Portland to La Crosse
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Portland to La Crosse in November.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy2 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Portland-La Crosse flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Portland-La Crosse flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Portland-La Crosse flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Portland-La Crosse flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Portland-La Crosse flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Portland to La Crosse
Have a flexible travel schedule? Discover the best time to fly to La Crosse from Portland with our price prediction graph.
PDX-LSE
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Reviews of airlines servicing La Crosse
Get insights into the airlines that provide service to La Crosse. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to La Crosse. Reviews last updated November 11, 2026.
See what other customers who have flown with American Airlines from Portland to La Crosse have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Crew
7.9
Comfort
7.2
Overall
7.0
Entertainment
6.8
Boarding
7.4
Food
6.4
Reviews
1 / 20
10.0
ExcellentLinda,Jul 2026
ROA - CLT
Crew
7.9
Comfort
7.2
Overall
7.0
Entertainment
6.8
Boarding
7.4
Food
6.4
Reviews
1 / 20
10.0
ExcellentLinda,Jul 2026
ROA - CLT
Related info for your journey
Find useful and relevant information for your journey from Portland to La Crosse. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near La Crosse?
Book flights to La Crosse if you plan to visit one of these locationsDecorah
Winona
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Other flights to La Crosse
Explore flights to La Crosse departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on November 11, 2026.
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Top airline flying from Portland to La Crosse
Discover the top airline that operate flights from Portland to La Crosse. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated November 11, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$338 | Average$660 | FlexibilityNo cancel fee | On-time71% |