$359+ Cheap flights from Portland to La Crosse (PDX - LSE)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/12. Fares are subject to change and may not be available on all flights or dates of travel.
PDX — LSE
Oct 2 — Oct 91
Round-trip
1 adult, Economy
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Find cheap flights from Portland to La Crosse with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Portland to La Crosse
Cheapest
Best
Last-minute
One-way
Cheapest flights from Portland to La CrosseExplore the most affordable flight options available from Portland to La Crosse. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 2, 2026.
Explore the most affordable flight options available from Portland to La Crosse. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 2, 2026.
This American Airlines deal was found by Cheapflights users on 8/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/126:01 am -
1 stop8h 51m
Wed 9/165:22 pm -
1 stop8h 45m
Deal found 8/28![American Airlines logo]()
$450
This American Airlines deal was found by Cheapflights users on 8/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/75:59 am -
1 stop8h 51m
Sat 9/125:22 pm -
1 stop8h 45m
Deal found 8/30![American Airlines logo]()
$560
This American Airlines deal was found by Cheapflights users on 8/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/2112:01 pm -
2 stops10h 19m
Sat 9/265:22 pm -
1 stop8h 45m
Deal found 8/29![American Airlines logo]()
$601
This American Airlines deal was found by Cheapflights users on 8/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/1411:08 pm -
1 stop10h 14m
Sat 9/1912:26 pm -
1 stop13h 41m
Deal found 8/29![American Airlines logo]()
$655
This American Airlines deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/911:48 am -
1 stop10h 32m
Sun 9/1312:26 pm -
1 stop13h 41m
Deal found 8/31![American Airlines logo]()
$721
Best flights from Portland to La CrosseDiscover carefully curated flight deals from Portland to La Crosse that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 2, 2026.
Discover carefully curated flight deals from Portland to La Crosse that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 2, 2026.
This American Airlines deal was found by Cheapflights users on 8/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/126:01 am -
1 stop8h 51m
Wed 9/165:22 pm -
1 stop8h 45m
Deal found 8/28![American Airlines logo]()
$450
This American Airlines deal was found by Cheapflights users on 8/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/216:01 am -
1 stop16h 19m
Sat 9/265:22 pm -
1 stop19h 33m
Deal found 8/29![American Airlines logo]()
$614
This American Airlines deal was found by Cheapflights users on 8/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/1411:08 pm -
1 stop10h 14m
Sat 9/1912:26 pm -
1 stop13h 41m
Deal found 8/29![American Airlines logo]()
$655
Last-minute flights from Portland to La CrosseDiscover last-minute flight deals from Portland to La Crosse. Data last updated September 2, 2026 and is based on user searches.
Discover last-minute flight deals from Portland to La Crosse. Data last updated September 2, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 8/30. Clicking the “Pick Dates ” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/75:59 am -
1 stop8h 51m
Sat 9/125:22 pm -
1 stop8h 45m
Deal found 8/30![American Airlines logo]()
$560
This American Airlines deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/911:48 am -
1 stop10h 32m
Sun 9/1312:26 pm -
1 stop13h 41m
Deal found 8/31![American Airlines logo]()
$721
This American Airlines deal was found by Cheapflights users on 8/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/126:01 am -
1 stop8h 51m
Wed 9/165:22 pm -
1 stop8h 45m
Deal found 8/28![American Airlines logo]()
$450
This American Airlines deal was found by Cheapflights users on 8/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/1411:08 pm -
1 stop10h 14m
Sat 9/1912:26 pm -
1 stop13h 41m
Deal found 8/29![American Airlines logo]()
$655
This American Airlines deal was found by Cheapflights users on 8/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/2112:01 pm -
2 stops10h 19m
Sat 9/265:22 pm -
1 stop8h 45m
Deal found 8/29![American Airlines logo]()
$601
One-way flights from Portland to La CrosseSearch for one-way flight options from Portland to La Crosse. Find affordable one-way fares based on user searches. Data last updated September 2, 2026.
Search for one-way flight options from Portland to La Crosse. Find affordable one-way fares based on user searches. Data last updated September 2, 2026.
This Kiwi.com deal was found by Cheapflights users on 8/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/1212:24 pm -
3 stops46h 42m
Deal found 8/29![Multiple Airlines logo]()
$359
This American Airlines deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/126:01 am -
1 stop8h 51m
Deal found 9/1![American Airlines logo]()
$438
This American Airlines deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/1111:06 pm -
2 stops10h 16m
Deal found 9/1![American Airlines logo]()
$469
Find flight deals from Portland to La Crosse
Discover tips and strategies to find the most affordable flight options for your journey from Portland (PDX) to La Crosse (LSE). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 2, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $450 (American Airlines) |
One-way from | $359 (Kiwi.com) |
Cheapflights Fare Finder
Customize your flight search to find flights from Portland to La Crosse that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 2, 2026.
Use the filters below to find and compare flights from Portland to La Crosse that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Quickest round-trip
PortlandLa Crosse
PDX Portland - LSE La Crosse
PDXLSE
Portland
Sat 9/12
6:01 am-4:52 pm
1 stop8h 51m
La Crosse
Wed 9/16
5:22 pm-12:07 am
1 stop8h 45m
$450
PortlandLa Crosse
PDX Portland - LSE La Crosse
PDXLSE
Portland
Mon 9/21
6:01 am-12:20 am
1 stop16h 19m
La Crosse
Sat 9/26
5:22 pm-10:55 am
1 stop19h 33m
$614
PortlandLa Crosse
PDX Portland - LSE La Crosse
PDXLSE
Portland
Mon 9/14
11:08 pm-11:22 am
1 stop10h 14m
La Crosse
Sat 9/19
12:26 pm-12:07 am
1 stop13h 41m
$655
Cheapest one-way
PortlandLa Crosse
PDX Portland - LSE La Crosse
PDXLSE
Portland
Sat 9/12
12:24 pm-1:06 pm
3 stops46h 42m
$359
Quickest one-way
PortlandLa Crosse
PDX Portland - LSE La Crosse
PDXLSE
Portland
Sat 9/12
6:01 am-4:52 pm
1 stop8h 51m
$438
PortlandLa Crosse
PDX Portland - LSE La Crosse
PDXLSE
Portland
Fri 9/11
11:06 pm-11:22 am
2 stops10h 16m
$469
Sorted by cheapest first
Compare providers for flights from Portland to La Crosse
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Portland to La Crosse in September.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Portland-La Crosse flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Portland-La Crosse flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Portland-La Crosse flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Portland-La Crosse flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Portland-La Crosse flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Portland to La Crosse
Have a flexible travel schedule? Discover the best time to fly to La Crosse from Portland with our price prediction graph.
PDX-LSE
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Related info for your journey
Find useful and relevant information for your journey from Portland to La Crosse. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near La Crosse?
Book flights to La Crosse if you plan to visit one of these locationsDecorah
Winona
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