$287+ Cheap flights from Denver to La Crosse (DEN - LSE)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/10. Fares are subject to change and may not be available on all flights or dates of travel.
DEN — LSE
Oct 16 — Oct 231
Round-trip
1 adult, Economy
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Find cheap flights from Denver to La Crosse with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Denver to La Crosse
Cheapest
Best
Last-minute
One-way
Cheapest flights from Denver to La CrosseExplore the most affordable flight options available from Denver to La Crosse. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 16, 2026.
Explore the most affordable flight options available from Denver to La Crosse. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 16, 2026.
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/106:11 pm -
1 stop5h 07m
Sat 11/146:52 pm -
1 stop6h 34m
Deal found 9/15![American Airlines logo]()
$287
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/156:09 pm -
1 stop4h 50m
Tue 10/206:50 pm -
1 stop6h 46m
Deal found 9/15![American Airlines logo]()
$362
This American Airlines deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/136:09 pm -
1 stop4h 50m
Sat 10/176:50 pm -
1 stop6h 46m
Deal found 9/12![American Airlines logo]()
$380
This American Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/106:09 pm -
1 stop4h 50m
Tue 10/136:50 pm -
1 stop6h 46m
Deal found 9/13![American Airlines logo]()
$416
This Kiwi.com deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/27:00 am -
1 stop11h 16m
Sun 10/411:06 am -
2 stops25h 11m
Deal found 9/14![Multiple Airlines logo]()
$429
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/156:09 pm -
1 stop4h 50m
Thu 10/226:55 pm -
1 stop6h 41m
Deal found 9/15![American Airlines logo]()
$437
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/256:01 pm -
1 stop5h 19m
Tue 9/295:53 am -
1 stop5h 09m
Deal found 9/10![American Airlines logo]()
$442
This American Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/116:01 pm -
1 stop5h 19m
Sat 9/125:53 am -
1 stop6h 42m
Deal found 9/11![American Airlines logo]()
$445
Best flights from Denver to La CrosseDiscover carefully curated flight deals from Denver to La Crosse that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 16, 2026.
Discover carefully curated flight deals from Denver to La Crosse that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 16, 2026.
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/106:11 pm -
1 stop5h 07m
Sat 11/146:52 pm -
1 stop6h 34m
Deal found 9/15![American Airlines logo]()
$287
This Kiwi.com deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/27:00 am -
1 stop11h 16m
Sun 10/411:06 am -
2 stops25h 11m
Deal found 9/14![Multiple Airlines logo]()
$429
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/156:09 pm -
1 stop4h 50m
Tue 10/206:50 pm -
1 stop6h 46m
Deal found 9/15![American Airlines logo]()
$362
This American Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/106:09 pm -
1 stop4h 50m
Tue 10/136:50 pm -
1 stop6h 46m
Deal found 9/13![American Airlines logo]()
$416
This American Airlines deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/136:09 pm -
1 stop4h 50m
Sat 10/176:58 am -
2 stops11h 48m
Deal found 9/12![American Airlines logo]()
$422
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/156:09 pm -
1 stop4h 50m
Thu 10/226:55 pm -
1 stop6h 41m
Deal found 9/15![American Airlines logo]()
$437
This American Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/186:01 pm -
1 stop5h 19m
Sat 9/195:53 am -
1 stop5h 09m
Deal found 9/13![American Airlines logo]()
$445
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/2510:47 am -
2 stops12h 33m
Tue 9/295:53 am -
1 stop5h 09m
Deal found 9/10![American Airlines logo]()
$447
This American Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/101:20 pm -
2 stops9h 39m
Mon 10/126:55 pm -
1 stop6h 41m
Deal found 9/13![American Airlines logo]()
$451
This American Airlines deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/156:09 pm -
1 stop4h 50m
Sat 10/176:50 pm -
1 stop6h 46m
Deal found 9/12![American Airlines logo]()
$455
Last-minute flights from Denver to La CrosseDiscover last-minute flight deals from Denver to La Crosse. Data last updated September 16, 2026 and is based on user searches.
Discover last-minute flight deals from Denver to La Crosse. Data last updated September 16, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/176:01 pm -
1 stop5h 19m
Sat 9/195:53 am -
1 stop5h 09m
Deal found 9/13![American Airlines logo]()
$445
This American Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/181:17 pm -
2 stops10h 03m
Sat 9/1912:26 pm -
2 stops11h 08m
Deal found 9/13![American Airlines logo]()
$456
This Kiwi.com deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/27:00 am -
1 stop11h 16m
Sun 10/411:06 am -
2 stops25h 11m
Deal found 9/14![Multiple Airlines logo]()
$429
This American Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/106:09 pm -
1 stop4h 50m
Tue 10/136:50 pm -
1 stop6h 46m
Deal found 9/13![American Airlines logo]()
$416
This American Airlines deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/136:09 pm -
1 stop4h 50m
Sat 10/176:50 pm -
1 stop6h 46m
Deal found 9/12![American Airlines logo]()
$380
This American Airlines deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/146:30 am -
2 stops10h 50m
Sat 10/176:58 am -
2 stops11h 48m
Deal found 9/12![American Airlines logo]()
$480
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/156:09 pm -
1 stop4h 50m
Tue 10/206:50 pm -
1 stop6h 46m
Deal found 9/15![American Airlines logo]()
$362
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/156:09 pm -
1 stop4h 50m
Thu 10/226:55 pm -
1 stop6h 41m
Deal found 9/15![American Airlines logo]()
$437
This American Airlines deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/156:09 pm -
1 stop4h 50m
Sat 10/176:50 pm -
1 stop6h 46m
Deal found 9/12![American Airlines logo]()
$455
One-way flights from Denver to La CrosseSearch for one-way flight options from Denver to La Crosse. Find affordable one-way fares based on user searches. Data last updated September 16, 2026.
Search for one-way flight options from Denver to La Crosse. Find affordable one-way fares based on user searches. Data last updated September 16, 2026.
This Kiwi.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/16:30 am -
3 stops50h 59m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/15![Multiple Airlines logo]()
$306
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/112:21 pm -
1 stop10h 59m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/15![American Airlines logo]()
$348
Find flight deals from Denver to La Crosse
Discover tips and strategies to find the most affordable flight options for your journey from Denver (DEN) to La Crosse (LSE). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 16, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $287 (American Airlines) |
Cheapflights Fare Finder
Customize your flight search to find flights from Denver to La Crosse that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 16, 2026.
Use the filters below to find and compare flights from Denver to La Crosse that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
DenverLa Crosse
DEN Denver Intl - LSE La Crosse
DENLSE
Denver Intl
Tue 11/10
6:11 pm-12:18 am
1 stop5h 07m
La Crosse
Sat 11/14
6:52 pm-12:26 am
1 stop6h 34m
$287
DenverLa Crosse
DEN Denver Intl - LSE La Crosse
DENLSE
Denver Intl
Tue 12/1
6:30 am-10:29 am
3 stops50h 59m
La Crosse
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$306
DenverLa Crosse
DEN Denver Intl - LSE La Crosse
DENLSE
Denver Intl
Tue 12/1
12:21 pm-12:20 am
1 stop10h 59m
La Crosse
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$348
DenverLa Crosse
DEN Denver Intl - LSE La Crosse
DENLSE
Denver Intl
Thu 10/15
6:09 pm-11:59 pm
1 stop4h 50m
La Crosse
Tue 10/20
6:50 pm-12:36 am
1 stop6h 46m
$362
DenverLa Crosse
DEN Denver Intl - LSE La Crosse
DENLSE
Denver Intl
Sat 10/10
6:09 pm-11:59 pm
1 stop4h 50m
La Crosse
Tue 10/13
6:50 pm-12:36 am
1 stop6h 46m
$416
DenverLa Crosse
DEN Denver Intl - LSE La Crosse
DENLSE
Denver Intl
Tue 10/13
6:09 pm-11:59 pm
1 stop4h 50m
La Crosse
Sat 10/17
6:58 am-5:46 pm
2 stops11h 48m
$422
DenverLa Crosse
DEN Denver Intl - LSE La Crosse
DENLSE
Denver Intl
Fri 10/2
7:00 am-7:16 pm
1 stop11h 16m
La Crosse
Sun 10/4
11:06 am-11:17 am
2 stops25h 11m
$429
DenverLa Crosse
DEN Denver Intl - LSE La Crosse
DENLSE
Denver Intl
Thu 10/15
6:09 pm-11:59 pm
1 stop4h 50m
La Crosse
Thu 10/22
6:55 pm-12:36 am
1 stop6h 41m
$437
Quickest round-trip
DenverLa Crosse
DEN Denver Intl - LSE La Crosse
DENLSE
Denver Intl
Fri 9/18
6:01 pm-12:20 am
1 stop5h 19m
La Crosse
Sat 9/19
5:53 am-10:02 am
1 stop5h 09m
$445
DenverLa Crosse
DEN Denver Intl - LSE La Crosse
DENLSE
Denver Intl
Fri 9/25
10:47 am-12:20 am
2 stops12h 33m
La Crosse
Tue 9/29
5:53 am-10:02 am
1 stop5h 09m
$447
Showing 1-10 of 12 resultsSorted by cheapest first
Compare providers for flights from Denver to La Crosse
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Denver to La Crosse in September.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Denver-La Crosse flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Denver-La Crosse flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Denver-La Crosse flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Denver-La Crosse flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Denver-La Crosse flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Denver to La Crosse
Have a flexible travel schedule? Discover the best time to fly to La Crosse from Denver with our price prediction graph.
DEN-LSE
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Reviews of airlines servicing La Crosse
Get insights into the airlines that provide service to La Crosse. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to La Crosse. Reviews last updated September 16, 2026.
Get a feel of what it's like to fly with American Airlines from Denver to La Crosse by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Crew
7.9
Entertainment
6.8
Overall
7.1
Boarding
7.4
Comfort
7.2
Food
6.4
Reviews
1 / 20
10.0
ExcellentLinda,Jul 2026
ROA - CLT
Crew
7.9
Entertainment
6.8
Overall
7.1
Boarding
7.4
Comfort
7.2
Food
6.4
Reviews
1 / 20
10.0
ExcellentLinda,Jul 2026
ROA - CLT
Related info for your journey
Find useful and relevant information for your journey from Denver to La Crosse. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near La Crosse?
Book flights to La Crosse if you plan to visit one of these locationsDecorah
Winona
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Explore flights to La Crosse departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on September 16, 2026.
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Top airline flying from Denver to La Crosse
Discover the top airline that operate flights from Denver to La Crosse. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 16, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$274 | Average$494 | FlexibilityNo cancel fee | On-time71% |