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$178+ Cheap flights from Wilmington to Knoxville (ILM - TYS)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/23. Fares are subject to change and may not be available on all flights or dates of travel.
ILM — TYS
Apr 19 — Apr 261
Sun 4/19
Sun 4/26
1 adult, Economy
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Cheap flight deals from Wilmington to Knoxville

Cheapest flights from Wilmington to Knoxville
Explore the most affordable flight options available from Wilmington to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 20, 2026.

This American Airlines deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/26:16 pm
ILM
-
TYS
1 stop5h 39m
American Airlines
Sat 5/98:57 am
TYS
-
ILM
1 stop5h 16m
American Airlines
Deal found 3/17$293
This American Airlines deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/316:05 am
ILM
-
TYS
1 stop3h 48m
American Airlines
Sat 4/47:02 am
TYS
-
ILM
1 stop3h 31m
American Airlines
Deal found 3/16$299
This American Airlines deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/305:00 am
ILM
-
TYS
1 stop3h 32m
American Airlines
Sat 5/27:00 am
TYS
-
ILM
1 stop5h 35m
American Airlines
Deal found 3/17$300
This American Airlines deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/126:35 am
ILM
-
TYS
1 stop3h 55m
American Airlines
Mon 8/178:25 pm
TYS
-
ILM
1 stop3h 34m
American Airlines
Deal found 3/17$309
This American Airlines deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/245:19 pm
ILM
-
TYS
1 stop3h 45m
American Airlines
Tue 3/314:04 pm
TYS
-
ILM
1 stop5h 31m
American Airlines
Deal found 3/16$319
This American Airlines deal was found by Cheapflights users on 3/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/116:57 pm
ILM
-
TYS
1 stop5h 02m
American Airlines
Sun 6/145:00 am
TYS
-
ILM
1 stop3h 30m
American Airlines
Deal found 3/15$334
This American Airlines deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/305:00 am
ILM
-
TYS
1 stop3h 32m
American Airlines
Mon 5/47:00 am
TYS
-
ILM
1 stop3h 34m
American Airlines
Deal found 3/16$338
This Delta deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/245:49 pm
ILM
-
TYS
1 stop6h 08m
Delta
Tue 3/315:40 am
TYS
-
ILM
1 stop3h 50m
Delta
Deal found 3/17$339
This American Airlines deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/165:00 am
ILM
-
TYS
1 stop3h 32m
American Airlines
Thu 4/235:00 am
TYS
-
ILM
1 stop3h 31m
American Airlines
Deal found 3/19$344
This American Airlines deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/25:08 am
ILM
-
TYS
1 stop3h 34m
American Airlines
Mon 4/65:00 am
TYS
-
ILM
1 stop3h 35m
American Airlines
Deal found 3/18$349
This American Airlines deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/46:57 pm
ILM
-
TYS
1 stop5h 02m
American Airlines
Sun 6/75:00 am
TYS
-
ILM
1 stop3h 30m
American Airlines
Deal found 3/16$358

Find flight deals from Wilmington to Knoxville

Discover tips and strategies to find the most affordable flight options for your journey from Wilmington (ILM) to Knoxville (TYS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated March 20, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$293
(American Airlines)

One-way from

$178
(Kiwi.com)

Popular in

November

Cheapest in

February

Average price

$485
Provider with most accurate pricing for Wilmington New Hanover County-Knoxville McGhee Tyson flight deals.
Search Deals
Provider most trusted by Cheapflights users for Wilmington New Hanover County-Knoxville McGhee Tyson flights.
Search Deals
From Wilmington New Hanover County to Knoxville McGhee Tyson
Search Deals
One-way flight from Wilmington New Hanover County to Knoxville McGhee Tyson
Search Deals
Highest demand for flights based on searches. 19% potential increase in price ($93 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 6% potential price decrease ($23 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in March 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Wilmington to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 20, 2026.
Use the filters below to find and compare flights from Wilmington to Knoxville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

WilmingtonKnoxville

ILM - TYS

ILMTYS

Wilmington New Hanover County

Thu 4/30

8:17 pm-11:55 pm

1 stop3h 38m

Knoxville McGhee Tyson

Sat 5/2

8:57 am-12:35 pm

1 stop3h 38m

$335

WilmingtonKnoxville

ILM - TYS

ILMTYS

Wilmington New Hanover County

Thu 4/2

5:08 am-8:42 am

1 stop3h 34m

Knoxville McGhee Tyson

Mon 4/6

5:00 am-8:35 am

1 stop3h 35m

$349

WilmingtonKnoxville

ILM - TYS

ILMTYS

Wilmington New Hanover County

Sat 7/18

6:58 pm-12:15 am

1 stop5h 17m

Knoxville McGhee Tyson

Thu 7/23

5:03 am-8:20 am

1 stop3h 17m

$363

WilmingtonKnoxville

ILM - TYS

ILMTYS

Wilmington New Hanover County

Fri 6/12

2:25 pm-11:34 pm

1 stop9h 09m

Knoxville McGhee Tyson

Sun 6/14

7:01 pm-2:59 pm

2 stops19h 58m

$436
Quickest round-trip

WilmingtonKnoxville

ILM - TYS

ILMTYS

Wilmington New Hanover County

Thu 4/30

5:00 am-8:32 am

1 stop3h 32m

Knoxville McGhee Tyson

Sun 5/3

5:00 am-8:31 am

1 stop3h 31m

$452

WilmingtonKnoxville

ILM - TYS

ILMTYS

Wilmington New Hanover County

Sat 8/22

4:09 pm-4:59 pm

1 stop24h 50m

Knoxville McGhee Tyson

Wed 8/26

5:57 pm-3:28 pm

1 stop21h 31m

$692
Cheapest one-way

WilmingtonKnoxville

ILM - TYS

ILMTYS

Wilmington New Hanover County

Sun 4/5

10:09 pm-11:10 am

3 stops37h 01m

$256

WilmingtonKnoxville

ILM - TYS

ILMTYS

Wilmington New Hanover County

Sat 6/6

5:09 am-10:36 am

1 stop5h 27m

$258
Quickest one-way

WilmingtonKnoxville

ILM - TYS

ILMTYS

Wilmington New Hanover County

Tue 6/23

10:20 am-3:06 pm

1 stop4h 46m

$268

WilmingtonKnoxville

ILM - TYS

ILMTYS

Wilmington New Hanover County

Mon 4/6

3:50 pm-4:04 pm

2 stops24h 14m

$305

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/16

Showing 1-10 of 13 resultsSorted by cheapest first
1
2

Compare providers for flights from Wilmington to Knoxville

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Wilmington to Knoxville in March.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Wilmington-Knoxville flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Wilmington-Knoxville flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Wilmington-Knoxville flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Wilmington-Knoxville flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Wilmington-Knoxville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Wilmington to Knoxville

Have a flexible travel schedule? Discover the best time to fly to Knoxville from Wilmington with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Wilmington to Knoxville

What is the cheapest month to book a flight from Wilmington to Knoxville?

Currently, September is the cheapest month in which you can book a flight from Wilmington to Knoxville (average of $209). Flying from Wilmington to Knoxville in November is currently the most expensive (average of $295). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Knoxville

Get insights into the airlines that provide service to Knoxville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Knoxville. Reviews last updated March 20, 2026.
Peruse reviews from past customers who have flown with American Airlines from Wilmington to Knoxville to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.1
Good
11,481 reviews

Entertainment

6.9

Comfort

7.2

Food

6.4

Boarding

7.5

Overall

7.1

Crew

7.9

Reviews

1 / 20
2.0
Mediocre

Anonymous,Mar 2026

MIA - SFO

Horrible. When they power flights for other airlines there is nothing they can do to change or accommodate any changes
American Airlines
7.1
Good
11,481 reviews
American Airlines
7.1
Good
11,481 reviews

Entertainment

6.9

Comfort

7.2

Food

6.4

Boarding

7.5

Overall

7.1

Crew

7.9

Reviews

1 / 20
2.0
Mediocre

Anonymous,Mar 2026

MIA - SFO

Horrible. When they power flights for other airlines there is nothing they can do to change or accommodate any changes

Related info for your journey

Find useful and relevant information for your journey from Wilmington to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Wilmington to Knoxville?

    For as low as $335, American Airlines can have you in Knoxville from Wilmington in 3h 38m. The distance from Wilmington to Knoxville is about 360 mi.

  • What is the cheapest airline to fly from Wilmington to Knoxville round-trip?

    Cheapflights users have booked flights from Wilmington to Knoxville round-trip from $228. American Airlines is currently priced 40% below the average price you’ll pay for this route.

  • Can I find deals for flights from Wilmington to Knoxville that include hotel bookings?

    Yes. In addition to deals on Wilmington to Knoxville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Wilmington to Knoxville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Wilmington to Knoxville.

  • Can I find deals for business class flights from Wilmington to Knoxville?

    Yes. Cheapflights offers flight deals from Wilmington to Knoxville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Wilmington to Knoxville?

    Currently, September is the cheapest month in which you can book a flight from Wilmington to Knoxville (average of $209). Flying from Wilmington to Knoxville in November is currently the most expensive (average of $295). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Cherokee
Crossville
Corbin
Morristown
Bryson City
Alcoa
Murphy
Oak Ridge

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Top airline flying from Wilmington to Knoxville

Discover the top airline that operate flights from Wilmington to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 20, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$228Average$363FlexibilityNo cancel feeOn-time71%

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