HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Knoxville

$163+ Cheap flights from Wilmington to Knoxville (ILM - TYS)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/19. Fares are subject to change and may not be available on all flights or dates of travel.
ILM — TYS
Dec 5 — Dec 121
Fri 12/5
Fri 12/12
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Wilmington to Knoxville with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Find flight deals from Wilmington to Knoxville

Cheapest flights from Wilmington to Knoxville
Explore the most affordable flight options available from Wilmington to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 5, 2025.

This Kiwi.com deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/121:00 pmILM - TYS
1 stop9h 12mMultiple Airlines
Sun 12/145:42 pmTYS - ILM
1 stop18h 38mMultiple Airlines
Deal found 11/4$244
This American Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/188:12 amILM - TYS
1 stop3h 34mAmerican Airlines
Sat 11/225:05 amTYS - ILM
1 stop3h 12mAmerican Airlines
Deal found 11/3$259
This American Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/116:00 amILM - TYS
1 stop5h 46mAmerican Airlines
Sat 11/154:15 pmTYS - ILM
1 stop5h 50mAmerican Airlines
Deal found 11/3$299
This Mytrip deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/179:00 amILM - TYS
2 stops23h 18mMultiple Airlines
Fri 12/199:25 pmTYS - ILM
2 stops24h 30mMultiple Airlines
Deal found 11/5$310
This American Airlines deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/87:07 amILM - TYS
1 stop5h 51mAmerican Airlines
Mon 11/105:07 pmTYS - ILM
1 stop6h 52mAmerican Airlines
Deal found 11/4$319
This Mytrip deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/235:03 pmILM - TYS
2 stops17h 15mMultiple Airlines
Sat 12/272:23 pmTYS - ILM
1 stop7h 32mMultiple Airlines
Deal found 11/3$336
This American Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/306:18 pmILM - TYS
1 stop3h 40mAmerican Airlines
Sun 1/47:00 amTYS - ILM
1 stop5h 31mAmerican Airlines
Deal found 11/3$344
This Delta deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/1710:26 amILM - TYS
1 stop4h 26mDelta
Fri 12/195:40 amTYS - ILM
1 stop4h 01mDelta
Deal found 11/5$353
This Delta deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/122:23 pmILM - TYS
1 stop5h 42mDelta
Sun 12/147:59 pmTYS - ILM
1 stop3h 18mDelta
Deal found 11/2$389

Cheap flight deals from Wilmington to Knoxville

Discover tips and strategies to find the most affordable flight options for your journey from Wilmington (ILM) to Knoxville (TYS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated November 5, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$229
(Delta)

One-way from

$163
(Mytrip)

Popular in

November

Cheapest in

December

Average price

$581
Provider with most accurate pricing for Wilmington New Hanover County-Knoxville McGhee Tyson flight deals.
Search Deals
Provider most trusted by Cheapflights users for Wilmington New Hanover County-Knoxville McGhee Tyson flights.
Search Deals
From Wilmington New Hanover County to Knoxville McGhee Tyson
Search Deals
One-way flight from Wilmington New Hanover County to Knoxville McGhee Tyson
Search Deals
Highest demand for flights based on searches. 3% potential increase in price ($12 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 5% potential price decrease ($20 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in November 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Wilmington to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 5, 2025.
Use the filters below to find and compare flights from Wilmington to Knoxville that are best for you.

Fly from

Wilmington

Fly to

Knoxville

Route

Depart

Return

Price

WilmingtonKnoxville

ILM - TYS

ILMTYS

Wilmington New Hanover County

Sat 3/7

11:45 am-3:21 pm

1 stop3h 36m

Knoxville McGhee Tyson

Wed 3/11

5:30 am-9:37 am

1 stop4h 07m

$229

WilmingtonKnoxville

ILM - TYS

ILMTYS

Wilmington New Hanover County

Fri 12/12

1:00 pm-10:12 pm

1 stop9h 12m

Knoxville McGhee Tyson

Sun 12/14

5:23 pm-12:20 pm

2 stops18h 57m

$251

WilmingtonKnoxville

ILM - TYS

ILMTYS

Wilmington New Hanover County

Tue 11/18

8:12 am-11:46 am

1 stop3h 34m

Knoxville McGhee Tyson

Sat 11/22

5:05 am-8:17 am

1 stop3h 12m

$259

WilmingtonKnoxville

ILM - TYS

ILMTYS

Wilmington New Hanover County

Wed 12/17

9:00 am-8:18 am

2 stops23h 18m

Knoxville McGhee Tyson

Fri 12/19

8:53 am-10:35 pm

1 stop13h 42m

$310

WilmingtonKnoxville

ILM - TYS

ILMTYS

Wilmington New Hanover County

Tue 12/23

5:03 pm-10:18 am

2 stops17h 15m

Knoxville McGhee Tyson

Sat 12/27

2:23 pm-9:55 pm

1 stop7h 32m

$336

WilmingtonKnoxville

ILM - TYS

ILMTYS

Wilmington New Hanover County

Tue 12/30

6:18 pm-9:58 pm

1 stop3h 40m

Knoxville McGhee Tyson

Sun 1/4

7:00 am-12:31 pm

1 stop5h 31m

$344

WilmingtonKnoxville

ILM - TYS

ILMTYS

Wilmington New Hanover County

Wed 12/17

10:26 am-2:52 pm

1 stop4h 26m

Knoxville McGhee Tyson

Fri 12/19

5:40 am-9:41 am

1 stop4h 01m

$353

WilmingtonKnoxville

ILM - TYS

ILMTYS

Wilmington New Hanover County

Fri 12/12

2:23 pm-8:05 pm

1 stop5h 42m

Knoxville McGhee Tyson

Sun 12/14

7:59 pm-11:17 pm

1 stop3h 18m

$389

WilmingtonKnoxville

ILM - TYS

ILMTYS

Wilmington New Hanover County

Wed 11/19

11:42 am-11:34 am

2 stops23h 52m

$163

WilmingtonKnoxville

ILM - TYS

ILMTYS

Wilmington New Hanover County

Wed 11/19

6:00 am-9:37 am

1 stop3h 37m

$290

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/4

Showing 1-10 of 11 results
1
2

Compare providers for flights from Wilmington to Knoxville

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Wilmington to Knoxville in November.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star
eDreamsPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Wilmington-Knoxville flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Wilmington-Knoxville flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Wilmington-Knoxville flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Wilmington-Knoxville flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Wilmington-Knoxville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Wilmington to Knoxville

Have a flexible travel schedule? Discover the best time to fly to Knoxville from Wilmington with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Wilmington to Knoxville

What is the cheapest month to book a flight from Wilmington to Knoxville?

Currently, March is the cheapest month in which you can book a flight from Wilmington to Knoxville (average of $208). Flying from Wilmington to Knoxville in April is currently the most expensive (average of $277). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from ILM to TYS?

Find hourly flight availability from Wilmington to Knoxville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated November 5, 2025.

It’s optimal to fly from Wilmington to Knoxville at noon. By choosing this option you can save up to 46% on the cost of your flight, compared to a flight in the afternoon.

Reviews of airlines servicing Knoxville

Get insights into the airlines that provide service to Knoxville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Knoxville. Reviews last updated November 5, 2025.
Peruse reviews from past customers who have flown with American Airlines from Wilmington to Knoxville to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.2
Good
11,042 reviews

Entertainment

6.9

Boarding

7.5

Crew

8.0

Food

6.4

Comfort

7.2

Overall

7.2

Reviews

1 / 20
2.0
Mediocre

Jeremy,Sep 2025

SAN - PHL

Terrible. Bad customer service and unacceptable delay on the tarmac
American Airlines
7.2
Good
11,042 reviews
American Airlines
7.2
Good
11,042 reviews

Entertainment

6.9

Boarding

7.5

Crew

8.0

Food

6.4

Comfort

7.2

Overall

7.2

Reviews

1 / 20
2.0
Mediocre

Jeremy,Sep 2025

SAN - PHL

Terrible. Bad customer service and unacceptable delay on the tarmac

Related info for your journey

Find useful and relevant information for your journey from Wilmington to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Wilmington to Knoxville?

    For as low as $259, Delta can have you in Knoxville from Wilmington in 3h 34m. The distance from Wilmington to Knoxville is about 360 mi. This flight may include one or multiple stops.

  • What is the cheapest airline to fly from Wilmington to Knoxville round-trip?

    Cheapflights users have booked flights from Wilmington to Knoxville round-trip from $228. American Airlines is currently priced 36% below the average price you’ll pay for this route.

  • Can I find deals for flights from Wilmington to Knoxville that include hotel bookings?

    Yes. In addition to deals on Wilmington to Knoxville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Wilmington to Knoxville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Wilmington to Knoxville.

  • Can I find deals for business class flights from Wilmington to Knoxville?

    Yes. Cheapflights offers flight deals from Wilmington to Knoxville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Wilmington to Knoxville?

    Currently, March is the cheapest month in which you can book a flight from Wilmington to Knoxville (average of $208). Flying from Wilmington to Knoxville in April is currently the most expensive (average of $277). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Morristown
Cherokee
Crossville
Corbin
Bryson City
Alcoa
Oak Ridge
Murphy

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Wilmington to Knoxville

See prices for flight routes from nearby airports that may be better suited for you.
Raleigh to Nashville flights
Charlotte to Nashville flights
Norfolk to Nashville flights
Charlotte to Memphis flights
Greensboro to Nashville flights
Norfolk to Memphis flights
Myrtle Beach to Nashville flights
Wilmington to Nashville flights
Raleigh to Knoxville flights
Raleigh to Memphis flights
Greensboro to Memphis flights
Myrtle Beach to Knoxville flights
Knoxville to Memphis flights
Knoxville to Nashville flights
Charlotte to Knoxville flights
Asheville to Memphis flights
Raleigh to Chattanooga flights
Jacksonville to Nashville flights
Asheville to Nashville flights
Charlotte to Chattanooga flights
Myrtle Beach to Memphis flights
New Bern to Nashville flights
Greensboro to Chattanooga flights
Jacksonville to Knoxville flights
Blountville to Nashville flights
Norfolk to Knoxville flights
Wilmington to Memphis flights
Fayetteville to Nashville flights
Norfolk to Chattanooga flights
Greenville to Knoxville flights
Raleigh to Blountville flights
Jacksonville to Memphis flights
Blountville to Memphis flights
Fayetteville to Memphis flights
New Bern to Knoxville flights
New Bern to Chattanooga flights
Greenville to Nashville flights
Jacksonville to Blountville flights
Knoxville to Chattanooga flights
Greenville to Memphis flights
New Bern to Blountville flights
New Bern to Memphis flights
Blountville to Knoxville flights

Top airline flying from Wilmington to Knoxville

Discover the top airline that operate flights from Wilmington to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 5, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$228Average$316FlexibilityNo cancel feeOn-time71%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.