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$200+ Cheap flights from Wilmington to Knoxville (ILM - TYS)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/23. Fares are subject to change and may not be available on all flights or dates of travel.
ILM — TYS
Aug 22 — Aug 291
Fri 8/22
Fri 8/29
1 adult, Economy
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Cheap flight deals from Wilmington to Knoxville

Discover tips and strategies to find the most affordable flight options for your journey from Wilmington (ILM) to Knoxville (TYS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated August 17, 2025.

Round-trip from

$233
(Mytrip)

One-way from

$200
(Mytrip)

Popular in

November

Cheapest in

December

Average price

$308
From Wilmington New Hanover County to Knoxville McGhee Tyson
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One-way flight from Wilmington New Hanover County to Knoxville McGhee Tyson
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Highest demand for flights based on searches. 8% potential increase in price ($30 potential increase over avg. RT price).
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Cheapest flight prices on average. 6% potential price decrease ($21 potential savings vs. average RT price).
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Average for round-trip flights in August 2025
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Find flight deals from Wilmington to Knoxville

Cheapest flights from Wilmington to Knoxville
Explore the most affordable flight options available from Wilmington to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 17, 2025.

This Mytrip deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/298:00 amILM - TYS
1 stop8h 25mMultiple Airlines
Fri 9/57:15 amTYS - ILM
2 stops16h 13mMultiple Airlines
Deal found 8/16$233
This American Airlines deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/295:00 amILM - TYS
1 stop4h 09mAmerican Airlines
Fri 9/52:08 pmTYS - ILM
1 stop4h 15mAmerican Airlines
Deal found 8/16$254
This American Airlines deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/277:40 pmILM - TYS
1 stop4h 10mAmerican Airlines
Mon 11/35:07 pmTYS - ILM
1 stop6h 37mAmerican Airlines
Deal found 8/17$259
This Mytrip deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/317:00 amILM - TYS
2 stops13h 22mMultiple Airlines
Thu 9/42:06 pmTYS - ILM
1 stop8h 12mMultiple Airlines
Deal found 8/16$267
This American Airlines deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/236:01 pmILM - TYS
1 stop4h 14mAmerican Airlines
Tue 8/263:41 pmTYS - ILM
1 stop4h 43mAmerican Airlines
Deal found 8/16$329
This American Airlines deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/125:36 pmILM - TYS
1 stop5h 27mAmerican Airlines
Mon 9/157:45 pmTYS - ILM
1 stop3h 23mAmerican Airlines
Deal found 8/17$334
This Mytrip deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/236:08 pmILM - TYS
2 stops24h 04mMultiple Airlines
Sat 10/258:00 amTYS - ILM
3 stops28h 38mMultiple Airlines
Deal found 8/17$388
This American Airlines deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/316:35 amILM - TYS
1 stop3h 55mAmerican Airlines
Thu 9/48:23 amTYS - ILM
1 stop5h 32mAmerican Airlines
Deal found 8/16$408

Cheapflights Fare Finder

 
Customize your flight search to find flights from Wilmington to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 17, 2025.
Use the filters below to find and compare flights from Wilmington to Knoxville that are best for you.

Fly from

Wilmington

Fly to

Knoxville

Route

Depart

Return

Price

WilmingtonKnoxville

ILM - TYS

ILMTYS

Wilmington New Hanover County

Fri 8/29

8:00 am-4:25 pm

1 stop8h 25m

Knoxville McGhee Tyson

Fri 9/5

7:15 am-11:28 pm

2 stops16h 13m

$233

WilmingtonKnoxville

ILM - TYS

ILMTYS

Wilmington New Hanover County

Fri 8/29

5:00 am-9:09 am

1 stop4h 09m

Knoxville McGhee Tyson

Fri 9/5

2:08 pm-6:23 pm

1 stop4h 15m

$254

WilmingtonKnoxville

ILM - TYS

ILMTYS

Wilmington New Hanover County

Mon 10/27

7:40 pm-11:50 pm

1 stop4h 10m

Knoxville McGhee Tyson

Mon 11/3

5:07 pm-11:44 pm

1 stop6h 37m

$259

WilmingtonKnoxville

ILM - TYS

ILMTYS

Wilmington New Hanover County

Sun 8/31

7:00 am-8:22 pm

2 stops13h 22m

Knoxville McGhee Tyson

Thu 9/4

2:06 pm-10:18 pm

1 stop8h 12m

$267

WilmingtonKnoxville

ILM - TYS

ILMTYS

Wilmington New Hanover County

Fri 9/12

5:36 pm-11:03 pm

1 stop5h 27m

Knoxville McGhee Tyson

Mon 9/15

7:45 pm-11:08 pm

1 stop3h 23m

$334

WilmingtonKnoxville

ILM - TYS

ILMTYS

Wilmington New Hanover County

Sat 9/20

12:31 pm-4:49 pm

1 stop4h 18m

Knoxville McGhee Tyson

Sun 9/21

5:05 am-8:15 am

1 stop3h 10m

$334

WilmingtonKnoxville

ILM - TYS

ILMTYS

Wilmington New Hanover County

Thu 10/23

6:29 pm-11:50 pm

1 stop5h 21m

Knoxville McGhee Tyson

Sat 10/25

7:00 am-12:31 pm

1 stop5h 31m

$334

WilmingtonKnoxville

ILM - TYS

ILMTYS

Wilmington New Hanover County

Thu 10/23

6:08 pm-6:12 pm

2 stops24h 04m

Knoxville McGhee Tyson

Sat 10/25

8:00 am-12:38 pm

3 stops28h 38m

$388

WilmingtonKnoxville

ILM - TYS

ILMTYS

Wilmington New Hanover County

Fri 12/12

8:34 pm-12:05 am

1 stop3h 31m

Knoxville McGhee Tyson

Tue 12/23

5:08 am-8:21 am

1 stop3h 13m

$388

WilmingtonKnoxville

ILM - TYS

ILMTYS

Wilmington New Hanover County

Sun 8/31

6:35 am-10:30 am

1 stop3h 55m

Knoxville McGhee Tyson

Thu 9/4

8:23 am-1:55 pm

1 stop5h 32m

$408

Flights are sorted by cheapest round-trip flights first.

Deals found on 8/17

Showing 1-10 of 16 results
1
2

Best time to book a flight from Wilmington to Knoxville

Have a flexible travel schedule? Discover the best time to fly to Knoxville from Wilmington with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Wilmington to Knoxville

What is the cheapest month to book a flight from Wilmington to Knoxville?

Currently, January is the cheapest month in which you can book a flight from Wilmington to Knoxville (average of $294). Flying from Wilmington to Knoxville in March is currently the most expensive (average of $376). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from ILM to TYS?

Find hourly flight availability from Wilmington to Knoxville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated August 17, 2025.

It’s optimal to fly from Wilmington to Knoxville at noon. By choosing this option you can save up to 47% on the cost of your flight, compared to a flight in the afternoon.

Reviews of airlines servicing Knoxville

Get insights into the airlines that provide service to Knoxville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Knoxville. Reviews last updated August 17, 2025.
Peruse reviews from past customers who have flown with American Airlines from Wilmington to Knoxville to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.2
Good
10,000 reviews

Boarding

7.5

Entertainment

6.9

Overall

7.2

Comfort

7.2

Food

6.5

Crew

8.0

Reviews

1 / 20
2.0
Mediocre

Anonymous,Aug 2025

MIA - DCA

Flight delayed 5 hours and was told it was due to mechanical issues. Instead of providing lodging due to missed connecting flight, American changed the cause of delay to weather, which meant they were not able required to provide a hotel. To make matters worse, one of our checked bags was lost even though its status said it was “by the plane” but no one at the service desk seemed able to locate it.
American Airlines
7.2
Good
10,000 reviews
American Airlines
7.2
Good
10,000 reviews

Boarding

7.5

Entertainment

6.9

Overall

7.2

Comfort

7.2

Food

6.5

Crew

8.0

Reviews

1 / 20
2.0
Mediocre

Anonymous,Aug 2025

MIA - DCA

Flight delayed 5 hours and was told it was due to mechanical issues. Instead of providing lodging due to missed connecting flight, American changed the cause of delay to weather, which meant they were not able required to provide a hotel. To make matters worse, one of our checked bags was lost even though its status said it was “by the plane” but no one at the service desk seemed able to locate it.

Related info for your journey

Find useful and relevant information for your journey from Wilmington to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What is the cheapest airline to fly from Wilmington to Knoxville round-trip?

    Cheapflights users have booked flights from Wilmington to Knoxville round-trip from $228. American Airlines is currently priced 34% below the average price you’ll pay for this route.

  • Can I find deals for flights from Wilmington to Knoxville that include hotel bookings?

    Yes. In addition to deals on Wilmington to Knoxville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Wilmington to Knoxville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Wilmington to Knoxville.

  • Can I find deals for business class flights from Wilmington to Knoxville?

    Yes. Cheapflights offers flight deals from Wilmington to Knoxville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Wilmington to Knoxville?

    Currently, January is the cheapest month in which you can book a flight from Wilmington to Knoxville (average of $294). Flying from Wilmington to Knoxville in March is currently the most expensive (average of $376). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Morristown
Cherokee
Corbin
Alcoa
Oak Ridge
Murphy

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Top airline flying from Wilmington to Knoxville

Discover the top airline that operate flights from Wilmington to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 17, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$228Average$308FlexibilityNo cancel feeOn-time71%

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