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$239+ Cheap flights from Wilmington to Knoxville (ILM - TYS)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/25. Fares are subject to change and may not be available on all flights or dates of travel.
ILM — TYS
Oct 11 — Oct 181
Sat 10/11
Sat 10/18
1 adult, Economy
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Cheap flight deals from Wilmington to Knoxville

Discover tips and strategies to find the most affordable flight options for your journey from Wilmington (ILM) to Knoxville (TYS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 11, 2025.

Round-trip from

$239
(American Airlines)

Popular in

November

Cheapest in

December

Average price

$358
From Wilmington New Hanover County to Knoxville McGhee Tyson
Search Deals
Highest demand for flights based on searches. 6% potential increase in price ($26 potential increase over avg. RT price).
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Cheapest flight prices on average. 5% potential price decrease ($20 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Find flight deals from Wilmington to Knoxville

Cheapest flights from Wilmington to Knoxville
Explore the most affordable flight options available from Wilmington to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 11, 2025.

This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/257:59 pmILM - TYS
1 stop4h 08mAmerican Airlines
Mon 9/295:05 amTYS - ILM
1 stop4h 32mAmerican Airlines
Deal found 9/10$239
This American Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/247:11 pmILM - TYS
1 stop3h 52mAmerican Airlines
Wed 10/15:05 amTYS - ILM
1 stop4h 27mAmerican Airlines
Deal found 9/11$254
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/218:35 pmILM - TYS
1 stop3h 16mAmerican Airlines
Sun 11/235:05 amTYS - ILM
1 stop3h 12mAmerican Airlines
Deal found 9/10$259
This American Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/96:25 amILM - TYS
1 stop3h 07mAmerican Airlines
Mon 10/138:37 pmTYS - ILM
1 stop3h 31mAmerican Airlines
Deal found 9/11$338
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/56:00 amILM - TYS
1 stop3h 50mAmerican Airlines
Fri 11/74:38 pmTYS - ILM
1 stop4h 14mAmerican Airlines
Deal found 9/10$383
This American Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/232:49 pmILM - TYS
1 stop5h 07mAmerican Airlines
Sun 10/268:37 pmTYS - ILM
1 stop3h 31mAmerican Airlines
Deal found 9/9$387
This Kiwi.com deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/234:46 pmILM - TYS
1 stop19h 32mMultiple Airlines
Sun 10/269:15 pmTYS - ILM
2 stops15h 05mMultiple Airlines
Deal found 9/9$402
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/115:00 amILM - TYS
1 stop3h 37mAmerican Airlines
Sat 9/137:45 pmTYS - ILM
1 stop3h 23mAmerican Airlines
Deal found 9/10$424
This Mytrip deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/98:00 amILM - TYS
3 stops39h 16mMultiple Airlines
Mon 10/135:26 pmTYS - ILM
1 stop5h 16mMultiple Airlines
Deal found 9/11$527
This American Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/95:00 amILM - TYS
1 stop4h 32mAmerican Airlines
Sun 10/128:37 pmTYS - ILM
1 stop3h 31mAmerican Airlines
Deal found 9/11$583
This American Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/186:06 amILM - TYS
1 stop4h 26mAmerican Airlines
Sun 9/215:05 amTYS - ILM
1 stop3h 10mAmerican Airlines
Deal found 9/11$614

Cheapflights Fare Finder

 
Customize your flight search to find flights from Wilmington to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 11, 2025.
Use the filters below to find and compare flights from Wilmington to Knoxville that are best for you.

Fly from

Wilmington

Fly to

Knoxville

Route

Depart

Return

Price

WilmingtonKnoxville

ILM - TYS

ILMTYS

Wilmington New Hanover County

Thu 9/25

7:59 pm-12:07 am

1 stop4h 08m

Knoxville McGhee Tyson

Mon 9/29

5:05 am-9:37 am

1 stop4h 32m

$239

WilmingtonKnoxville

ILM - TYS

ILMTYS

Wilmington New Hanover County

Fri 9/26

5:36 pm-8:50 pm

1 stop3h 14m

Knoxville McGhee Tyson

Tue 9/30

8:23 am-11:39 am

1 stop3h 16m

$239

WilmingtonKnoxville

ILM - TYS

ILMTYS

Wilmington New Hanover County

Wed 9/24

7:11 pm-11:03 pm

1 stop3h 52m

Knoxville McGhee Tyson

Wed 10/1

5:05 am-9:32 am

1 stop4h 27m

$254

WilmingtonKnoxville

ILM - TYS

ILMTYS

Wilmington New Hanover County

Fri 11/21

8:35 pm-11:51 pm

1 stop3h 16m

Knoxville McGhee Tyson

Sun 11/23

5:05 am-8:17 am

1 stop3h 12m

$259

WilmingtonKnoxville

ILM - TYS

ILMTYS

Wilmington New Hanover County

Sat 3/7

10:20 am-3:06 pm

1 stop4h 46m

Knoxville McGhee Tyson

Wed 3/11

10:05 am-1:34 pm

1 stop3h 29m

$317

WilmingtonKnoxville

ILM - TYS

ILMTYS

Wilmington New Hanover County

Thu 10/9

6:25 am-9:32 am

1 stop3h 07m

Knoxville McGhee Tyson

Mon 10/13

8:37 pm-12:08 am

1 stop3h 31m

$338

WilmingtonKnoxville

ILM - TYS

ILMTYS

Wilmington New Hanover County

Wed 11/5

6:00 am-9:50 am

1 stop3h 50m

Knoxville McGhee Tyson

Fri 11/7

4:38 pm-8:52 pm

1 stop4h 14m

$383

WilmingtonKnoxville

ILM - TYS

ILMTYS

Wilmington New Hanover County

Thu 10/23

2:49 pm-7:56 pm

1 stop5h 07m

Knoxville McGhee Tyson

Sun 10/26

8:37 pm-12:08 am

1 stop3h 31m

$387

WilmingtonKnoxville

ILM - TYS

ILMTYS

Wilmington New Hanover County

Thu 10/23

4:46 pm-12:18 pm

1 stop19h 32m

Knoxville McGhee Tyson

Sun 10/26

9:15 pm-12:20 pm

2 stops15h 05m

$402

WilmingtonKnoxville

ILM - TYS

ILMTYS

Wilmington New Hanover County

Sat 3/7

8:40 pm-11:41 pm

1 stop3h 01m

Knoxville McGhee Tyson

Wed 3/11

11:10 am-6:59 pm

2 stops7h 49m

$407

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/10

Showing 1-10 of 15 results
1
2

Best time to book a flight from Wilmington to Knoxville

Have a flexible travel schedule? Discover the best time to fly to Knoxville from Wilmington with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Wilmington to Knoxville

What is the cheapest month to book a flight from Wilmington to Knoxville?

Currently, January is the cheapest month in which you can book a flight from Wilmington to Knoxville (average of $294). Flying from Wilmington to Knoxville in March is currently the most expensive (average of $376). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from ILM to TYS?

Find hourly flight availability from Wilmington to Knoxville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 11, 2025.

It’s optimal to fly from Wilmington to Knoxville at noon. By choosing this option you can save up to 47% on the cost of your flight, compared to a flight in the afternoon.

Reviews of airlines servicing Knoxville

Get insights into the airlines that provide service to Knoxville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Knoxville. Reviews last updated September 11, 2025.
Peruse reviews from past customers who have flown with American Airlines from Wilmington to Knoxville to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.2
Good
10,000 reviews

Entertainment

6.9

Crew

8.0

Boarding

7.5

Comfort

7.2

Overall

7.2

Food

6.4

Reviews

1 / 20
2.0
Mediocre

Jeremy,Sep 2025

SAN - PHL

Terrible. Bad customer service and unacceptable delay on the tarmac
American Airlines
7.2
Good
10,000 reviews
American Airlines
7.2
Good
10,000 reviews

Entertainment

6.9

Crew

8.0

Boarding

7.5

Comfort

7.2

Overall

7.2

Food

6.4

Reviews

1 / 20
2.0
Mediocre

Jeremy,Sep 2025

SAN - PHL

Terrible. Bad customer service and unacceptable delay on the tarmac

Related info for your journey

Find useful and relevant information for your journey from Wilmington to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Wilmington to Knoxville?

    For as low as $239, American Airlines can have you in Knoxville from Wilmington in 4h 08m. The distance from Wilmington to Knoxville is about 360 mi. This flight may include one or multiple stops.

  • What is the cheapest airline to fly from Wilmington to Knoxville round-trip?

    Cheapflights users have booked flights from Wilmington to Knoxville round-trip from $228. American Airlines is currently priced 35% below the average price you’ll pay for this route.

  • Can I find deals for flights from Wilmington to Knoxville that include hotel bookings?

    Yes. In addition to deals on Wilmington to Knoxville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Wilmington to Knoxville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Wilmington to Knoxville.

  • Can I find deals for business class flights from Wilmington to Knoxville?

    Yes. Cheapflights offers flight deals from Wilmington to Knoxville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Wilmington to Knoxville?

    Currently, January is the cheapest month in which you can book a flight from Wilmington to Knoxville (average of $294). Flying from Wilmington to Knoxville in March is currently the most expensive (average of $376). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Morristown
Cherokee
Corbin
Alcoa
Oak Ridge
Murphy

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Top airline flying from Wilmington to Knoxville

Discover the top airline that operate flights from Wilmington to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 11, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$228Average$328FlexibilityNo cancel feeOn-time71%

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