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Knoxville

$139+ Cheap flights from Wilkes-Barre, PA to Knoxville (TYS)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/4. Fares are subject to change and may not be available on all flights or dates of travel.
ABE — TYS
May 29 — Jun 51
Fri 5/29
Fri 6/5
1 adult, Economy
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Cheap flight deals from Wilkes-Barre to Knoxville

Cheapest flights from Wilkes-Barre to Knoxville
Explore the most affordable flight options available from Wilkes-Barre to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 29, 2026.

This Kiwi.com deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/149:19 pm
AVP
-
TYS
1 stop20h 11m
Multiple Airlines
Mon 5/181:15 pm
TYS
-
AVP
1 stop29h 12m
Multiple Airlines
Deal found 4/29$343
This Kiwi.com deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/109:19 pm
AVP
-
TYS
1 stop25h 05m
Multiple Airlines
Thu 5/149:40 pm
TYS
-
AVP
2 stops37h 53m
Multiple Airlines
Deal found 4/28$348
This United Airlines deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/35:37 pm
AVP
-
TYS
1 stop6h 58m
United Airlines
Tue 7/75:45 am
TYS
-
AVP
1 stop4h 03m
United Airlines
Deal found 4/27$358
This Kiwi.com deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/110:37 am
AVP
-
TYS
1 stop7h 22m
Multiple Airlines
Tue 7/75:00 pm
TYS
-
AVP
1 stop16h 57m
Multiple Airlines
Deal found 4/26$370
This United Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/35:37 pm
AVP
-
TYS
1 stop6h 58m
United Airlines
Mon 7/65:45 am
TYS
-
AVP
1 stop4h 03m
United Airlines
Deal found 4/28$378
This United Airlines deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/292:29 pm
AVP
-
TYS
1 stop6h 19m
United Airlines
Tue 9/110:00 am
TYS
-
AVP
1 stop4h 26m
United Airlines
Deal found 4/27$389
This Kiwi.com deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/49:19 pm
AVP
-
TYS
1 stop26h 20m
Multiple Airlines
Wed 6/241:02 pm
TYS
-
AVP
2 stops19h 50m
Multiple Airlines
Deal found 4/26$390
This United Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/203:10 pm
AVP
-
TYS
1 stop5h 18m
United Airlines
Mon 8/245:45 am
TYS
-
AVP
1 stop3h 55m
United Airlines
Deal found 4/29$395

Find flight deals from Wilkes-Barre to Knoxville

Keep the following information in mind while searching for Wilkes-Barre to Knoxville flight deals. Data was last updated April 29, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$339
(United Airlines)

One-way from

$139
(Kiwi.com)
Provider with most accurate pricing for Wilkes-Barre Scranton-Knoxville McGhee Tyson flight deals.
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Provider most trusted by Cheapflights users for Wilkes-Barre Scranton-Knoxville McGhee Tyson flights.
Search Deals
From Wilkes-Barre to Knoxville McGhee Tyson
Search Deals
One-way flight from Wilkes-Barre to Knoxville McGhee Tyson
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Wilkes-Barre to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 29, 2026.
Use the filters below to find and compare flights from Wilkes-Barre to Knoxville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

ScrantonKnoxville

AVP - TYS

AVPTYS

Wilkes-Barre Scranton

Thu 5/14

9:19 pm-5:30 pm

1 stop20h 11m

Knoxville McGhee Tyson

Mon 5/18

1:15 pm-6:27 pm

1 stop29h 12m

$343

ScrantonKnoxville

AVP - TYS

AVPTYS

Wilkes-Barre Scranton

Fri 7/3

5:37 pm-12:35 am

1 stop6h 58m

Knoxville McGhee Tyson

Tue 7/7

5:45 am-9:48 am

1 stop4h 03m

$358

ScrantonKnoxville

AVP - TYS

AVPTYS

Wilkes-Barre Scranton

Fri 7/3

5:37 pm-12:35 am

1 stop6h 58m

Knoxville McGhee Tyson

Mon 7/6

5:45 am-9:48 am

1 stop4h 03m

$378

ScrantonKnoxville

AVP - TYS

AVPTYS

Wilkes-Barre Scranton

Sat 8/29

3:10 pm-8:28 pm

1 stop5h 18m

Knoxville McGhee Tyson

Tue 9/1

6:30 am-2:26 pm

2 stops7h 56m

$394

ScrantonKnoxville

AVP - TYS

AVPTYS

Wilkes-Barre Scranton

Thu 8/20

3:10 pm-8:28 pm

1 stop5h 18m

Knoxville McGhee Tyson

Mon 8/24

6:30 am-2:26 pm

2 stops7h 56m

$400
Quickest round-trip

ScrantonKnoxville

AVP - TYS

AVPTYS

Wilkes-Barre Scranton

Thu 6/4

5:27 pm-9:58 pm

1 stop4h 31m

Knoxville McGhee Tyson

Sat 6/6

7:59 pm-12:18 am

1 stop4h 19m

$440

ScrantonKnoxville

AVP - TYS

AVPTYS

Wilkes-Barre Scranton

Tue 5/26

2:50 pm-8:56 pm

1 stop6h 06m

Knoxville McGhee Tyson

Tue 6/2

5:45 am-9:48 am

1 stop4h 03m

$483
Cheapest one-way

ScrantonKnoxville

AVP - TYS

AVPTYS

Wilkes-Barre Scranton

Thu 6/4

9:19 pm-9:50 pm

3 stops24h 31m

$214

ScrantonKnoxville

AVP - TYS

AVPTYS

Wilkes-Barre Scranton

Sat 6/6

5:32 pm-12:30 am

1 stop6h 58m

$279

ScrantonKnoxville

AVP - TYS

AVPTYS

Wilkes-Barre Scranton

Fri 6/5

5:27 pm-9:58 pm

1 stop4h 31m

$314

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/25

Showing 1-10 of 16 resultsSorted by cheapest first
1
2

Best time to book a flight from Wilkes-Barre to Knoxville

Have a flexible travel schedule? Discover the best time to fly to Knoxville from Wilkes-Barre with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Wilkes-Barre to Knoxville
No data available for this route at this time. Please check back soon.

Reviews of airlines servicing Knoxville

Get insights into the airlines that provide service to Knoxville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Knoxville. Reviews last updated April 29, 2026.
Peruse reviews from past customers who have flown with United Airlines from Wilkes-Barre to Knoxville to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
United Airlines
7.4
Good
9,680 reviews

Food

6.6

Overall

7.4

Crew

8.1

Boarding

7.7

Comfort

7.3

Entertainment

7.1

Reviews

1 / 20
8.0
Excellent

Anonymous,Apr 2026

DFW - EWR

The flight was on time. Crew was friendly. Will fly again. The seats was comfortable.
United Airlines
7.4
Good
9,680 reviews
United Airlines
7.4
Good
9,680 reviews

Food

6.6

Overall

7.4

Crew

8.1

Boarding

7.7

Comfort

7.3

Entertainment

7.1

Reviews

1 / 20
8.0
Excellent

Anonymous,Apr 2026

DFW - EWR

The flight was on time. Crew was friendly. Will fly again. The seats was comfortable.

Related info for your journey

Find useful and relevant information for your journey from Wilkes-Barre to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Knoxville from Wilkes-Barre?

    Knoxville McGhee Tyson (TYS) is the airport you will fly into if you book a flight from Wilkes-Barre to Knoxville. You should not have trouble finding flights to McGhee Tyson from Wilkes-Barre; the airport handles an average of 0 inbound flights from Wilkes-Barre per day. You should also have plenty of airline options to choose from since 4 airlines have flights to the Knoxville airport from Wilkes-Barre. It is only a 11.3 mi journey from McGhee Tyson (TYS) to Knoxville’s city center.

  • How long is the flight from Wilkes-Barre to Knoxville?

    For as low as $339, United Airlines can have you in Knoxville from Wilkes-Barre in 5h 35m. Wilkes-Barre and Knoxville are separated by a distance of 587 mi.

  • Can I find deals for flights from Wilkes-Barre to Knoxville that include hotel bookings?

    Yes. In addition to deals on Wilkes-Barre to Knoxville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Wilkes-Barre to Knoxville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Wilkes-Barre to Knoxville.

  • Can I find deals for business class flights from Wilkes-Barre to Knoxville?

    Yes. Cheapflights offers flight deals from Wilkes-Barre to Knoxville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Traveling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Cherokee
Crossville
Morristown
Bryson City
Murphy
Alcoa
Oak Ridge

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Alternative routes for Wilkes-Barre to Knoxville

See prices for flight routes from nearby airports that may be better suited for you.
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Top 4 airlines flying from Wilkes-Barre to Knoxville

Discover the top 4 airlines that operate flights from Wilkes-Barre to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 29, 2026.
AirlineCheapestAverageFlexibilityOn-time
Allegiant AirCheapest$95Average$255FlexibilityNo cancel feeOn-time88%
United AirlinesCheapest$248Average$464FlexibilityNo cancel feeOn-time69%
DeltaCheapest$278Average$659FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$358Average$557FlexibilityNo cancel feeOn-time71%

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