$153+ Cheap flights from Wilkes-Barre, PA to Knoxville (TYS)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/29. Fares are subject to change and may not be available on all flights or dates of travel.
ABE — TYS
Oct 15 — Oct 221
Round-trip
1 adult, Economy
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Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Wilkes-Barre to Knoxville
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Cheapest flights from Wilkes-Barre to KnoxvilleExplore the most affordable flight options available from Wilkes-Barre to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 15, 2026.
Explore the most affordable flight options available from Wilkes-Barre to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 15, 2026.
This United Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/1410:28 am -
1 stop4h 14m
Tue 10/209:45 am -
1 stop4h 27m
Deal found 9/14![United Airlines logo]()
$339
This Kiwi.com deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/188:59 pm -
1 stop14h 15m
Thu 10/229:05 am -
2 stops23h 58m
Deal found 9/14![Multiple Airlines logo]()
$377
This Kiwi.com deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/219:50 am -
2 stops25h 39m
Fri 10/239:28 pm -
1 stop11h 42m
Deal found 9/13![Multiple Airlines logo]()
$384
This Kiwi.com deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/39:50 am -
1 stop22h 15m
Sat 10/109:36 pm -
2 stops35h 27m
Deal found 9/14![Multiple Airlines logo]()
$419
This United Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/163:10 pm -
1 stop23h 32m
Fri 10/235:45 am -
1 stop4h 01m
Deal found 9/10![United Airlines logo]()
$495
This Kiwi.com deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/149:43 am -
1 stop23h 56m
Tue 9/2210:29 am -
2 stops24h 53m
Deal found 9/11![Multiple Airlines logo]()
$498
This United Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/243:10 pm -
1 stop5h 09m
Wed 10/286:45 am -
2 stops7h 31m
Deal found 9/10![United Airlines logo]()
$499
This Kiwi.com deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/149:43 am -
1 stop23h 56m
Thu 9/1711:34 am -
1 stop21h 29m
Deal found 9/11![Multiple Airlines logo]()
$502
This United Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/115:35 pm -
1 stop5h 14m
Tue 9/229:45 am -
1 stop4h 12m
Deal found 9/11![United Airlines logo]()
$504
Best flights from Wilkes-Barre to KnoxvilleDiscover carefully curated flight deals from Wilkes-Barre to Knoxville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 15, 2026.
Discover carefully curated flight deals from Wilkes-Barre to Knoxville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 15, 2026.
This United Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/1410:28 am -
1 stop4h 14m
Tue 10/209:45 am -
1 stop4h 27m
Deal found 9/14![United Airlines logo]()
$339
This Kiwi.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/169:43 am -
2 stops13h 23m
Fri 10/239:28 pm -
1 stop11h 42m
Deal found 9/10![Multiple Airlines logo]()
$506
This United Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/243:10 pm -
1 stop5h 09m
Wed 10/289:45 am -
1 stop4h 31m
Deal found 9/10![United Airlines logo]()
$494
This United Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/253:10 pm -
1 stop19h 27m
Tue 9/296:00 am -
2 stops8h 12m
Deal found 9/10![United Airlines logo]()
$603
This United Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/2010:28 am -
1 stop4h 14m
Thu 10/225:45 am -
1 stop4h 01m
Deal found 9/14![United Airlines logo]()
$619
Last-minute flights from Wilkes-Barre to KnoxvilleDiscover last-minute flight deals from Wilkes-Barre to Knoxville. Data last updated September 15, 2026 and is based on user searches.
Discover last-minute flight deals from Wilkes-Barre to Knoxville. Data last updated September 15, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/149:43 am -
1 stop23h 56m
Tue 9/2210:29 am -
2 stops24h 53m
Deal found 9/11![Multiple Airlines logo]()
$498
This Kiwi.com deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/149:43 am -
1 stop23h 56m
Thu 9/1711:34 am -
1 stop21h 29m
Deal found 9/11![Multiple Airlines logo]()
$502
This United Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/145:35 pm -
1 stop5h 14m
Sat 9/199:45 am -
1 stop4h 12m
Deal found 9/11![United Airlines logo]()
$504
This Kiwi.com deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/39:50 am -
1 stop22h 15m
Sat 10/109:36 pm -
2 stops35h 27m
Deal found 9/14![Multiple Airlines logo]()
$419
This United Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/1410:28 am -
1 stop4h 14m
Tue 10/209:45 am -
1 stop4h 27m
Deal found 9/14![United Airlines logo]()
$339
This United Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/163:10 pm -
1 stop23h 32m
Fri 10/235:45 am -
1 stop4h 01m
Deal found 9/10![United Airlines logo]()
$495
This Kiwi.com deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/188:59 pm -
1 stop14h 15m
Thu 10/229:05 am -
2 stops23h 58m
Deal found 9/14![Multiple Airlines logo]()
$377
This Kiwi.com deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/219:50 am -
2 stops25h 39m
Fri 10/239:28 pm -
1 stop11h 42m
Deal found 9/13![Multiple Airlines logo]()
$384
This United Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/243:10 pm -
1 stop5h 09m
Wed 10/286:45 am -
2 stops7h 31m
Deal found 9/10![United Airlines logo]()
$499
One-way flights from Wilkes-Barre to KnoxvilleSearch for one-way flight options from Wilkes-Barre to Knoxville. Find affordable one-way fares based on user searches. Data last updated September 15, 2026.
Search for one-way flight options from Wilkes-Barre to Knoxville. Find affordable one-way fares based on user searches. Data last updated September 15, 2026.
This Kiwi.com deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/298:59 pm -
1 stop15h 15m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/14![Multiple Airlines logo]()
$153
This United Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/3110:21 am -
1 stop4h 27m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/11![United Airlines logo]()
$300
Find flight deals from Wilkes-Barre to Knoxville
Keep the following information in mind while searching for Wilkes-Barre to Knoxville flight deals. Data was last updated September 15, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $339 (United Airlines) |
One-way from | $153 (Kiwi.com) |
Cheapflights Fare Finder
Customize your flight search to find flights from Wilkes-Barre to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 15, 2026.
Use the filters below to find and compare flights from Wilkes-Barre to Knoxville that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
ScrantonKnoxville
AVP Wilkes-Barre Scranton - TYS Knoxville McGhee Tyson
AVPTYS
Wilkes-Barre Scranton
Thu 10/29
8:59 pm-5:37 pm
2 stops20h 38m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$198
Quickest round-trip
ScrantonKnoxville
AVP Wilkes-Barre Scranton - TYS Knoxville McGhee Tyson
AVPTYS
Wilkes-Barre Scranton
Sat 10/31
10:21 am-2:48 pm
1 stop4h 27m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$300
ScrantonKnoxville
AVP Wilkes-Barre Scranton - TYS Knoxville McGhee Tyson
AVPTYS
Wilkes-Barre Scranton
Wed 10/14
10:28 am-2:42 pm
1 stop4h 14m
Knoxville McGhee Tyson
Tue 10/20
9:45 am-2:12 pm
1 stop4h 27m
$339
ScrantonKnoxville
AVP Wilkes-Barre Scranton - TYS Knoxville McGhee Tyson
AVPTYS
Wilkes-Barre Scranton
Sat 10/24
3:10 pm-8:19 pm
1 stop5h 09m
Knoxville McGhee Tyson
Wed 10/28
9:45 am-2:16 pm
1 stop4h 31m
$494
ScrantonKnoxville
AVP Wilkes-Barre Scranton - TYS Knoxville McGhee Tyson
AVPTYS
Wilkes-Barre Scranton
Fri 10/16
9:43 am-11:06 pm
2 stops13h 23m
Knoxville McGhee Tyson
Fri 10/23
9:28 pm-9:10 am
1 stop11h 42m
$506
ScrantonKnoxville
AVP Wilkes-Barre Scranton - TYS Knoxville McGhee Tyson
AVPTYS
Wilkes-Barre Scranton
Fri 9/25
3:10 pm-10:37 am
1 stop19h 27m
Knoxville McGhee Tyson
Tue 9/29
6:00 am-2:12 pm
2 stops8h 12m
$603
ScrantonKnoxville
AVP Wilkes-Barre Scranton - TYS Knoxville McGhee Tyson
AVPTYS
Wilkes-Barre Scranton
Tue 10/20
10:28 am-2:42 pm
1 stop4h 14m
Knoxville McGhee Tyson
Thu 10/22
5:45 am-9:46 am
1 stop4h 01m
$619
Sorted by cheapest first
Best time to book a flight from Wilkes-Barre to Knoxville
Have a flexible travel schedule? Discover the best time to fly to Knoxville from Wilkes-Barre with our price prediction graph.
AVP-TYS
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Wilkes-Barre to Knoxville
W1L-TYS
AVP-TYS
No data available for this route at this time. Please check back soon.
Reviews of airlines servicing Knoxville
Get insights into the airlines that provide service to Knoxville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Knoxville. Reviews last updated September 15, 2026.
Peruse reviews from past customers who have flown with United Airlines from Wilkes-Barre to Knoxville to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Food
6.7
Comfort
7.3
Entertainment
7.1
Overall
7.4
Crew
8.1
Boarding
7.7
Reviews
1 / 20
8.0
ExcellentAsha,Sep 2026
LGA - IAH
Food
6.7
Comfort
7.3
Entertainment
7.1
Overall
7.4
Crew
8.1
Boarding
7.7
Reviews
1 / 20
8.0
ExcellentAsha,Sep 2026
LGA - IAH
Related info for your journey
Find useful and relevant information for your journey from Wilkes-Barre to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Knoxville?
Book flights to Knoxville if you plan to visit one of these locationsCherokee
Crossville
Morristown
Bryson City
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Complete your trip
Complete your trip to Knoxville by adding a car rental and/or hotel reservation to your travel itinerary.
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Other flights to Knoxville
Explore flights to Knoxville departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on September 15, 2026.
Wilkes-Barre and Knoxville flights
Browse other Wilkes-Barre and Knoxville flight options. Last updated on September 15, 2026.
Popular flight searches
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Wilkes-Barre to Knoxville flights
Consider these flights traveling from Wilkes-Barre to Knoxville.
Top 4 airlines flying from Wilkes-Barre to Knoxville
Discover the top 4 airlines that operate flights from Wilkes-Barre to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 15, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$238 | Average$367 | FlexibilityNo cancel fee | On-time88% | |
| Cheapest$263 | Average$479 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$358 | Average$468 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$364 | Average$614 | FlexibilityNo cancel fee | On-timeN/A |