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$220+ Cheap flights from Wilkes-Barre, PA to Knoxville (TYS)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/30. Fares are subject to change and may not be available on all flights or dates of travel.
ABE — TYS
Apr 16 — Apr 231
Thu 4/16
Thu 4/23
1 adult, Economy
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Cheap flight deals from Wilkes-Barre to Knoxville

Cheapest flights from Wilkes-Barre to Knoxville
Explore the most affordable flight options available from Wilkes-Barre to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 17, 2026.

This United Airlines deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/156:00 am
AVP
-
TYS
1 stop4h 50m
United Airlines
Wed 4/227:20 pm
TYS
-
AVP
1 stop4h 24m
United Airlines
Deal found 3/16$374
This United Airlines deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/222:29 pm
AVP
-
TYS
1 stop6h 19m
United Airlines
Wed 8/265:45 am
TYS
-
AVP
1 stop3h 55m
United Airlines
Deal found 3/12$379
This United Airlines deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/243:25 pm
AVP
-
TYS
1 stop7h 09m
United Airlines
Fri 5/87:18 pm
TYS
-
AVP
1 stop4h 01m
United Airlines
Deal found 3/13$394
This United Airlines deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/316:00 am
AVP
-
TYS
2 stops10h 52m
United Airlines
Sat 4/47:00 am
TYS
-
AVP
1 stop7h 47m
United Airlines
Deal found 3/16$417
This American Airlines deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/255:27 pm
AVP
-
TYS
1 stop6h 20m
American Airlines
Wed 7/17:59 pm
TYS
-
AVP
1 stop4h 19m
American Airlines
Deal found 3/16$440
This Kiwi.com deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/2410:23 am
AVP
-
TYS
1 stop12h 01m
Multiple Airlines
Fri 5/81:15 pm
TYS
-
AVP
2 stops22h 18m
Multiple Airlines
Deal found 3/13$444

Find flight deals from Wilkes-Barre to Knoxville

Keep the following information in mind while searching for Wilkes-Barre to Knoxville flight deals. Data was last updated March 17, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$374
(United Airlines)

One-way from

$220
(Kiwi.com)

Popular in

October

Cheapest in

March

Average price

$315
Provider with most accurate pricing for Wilkes-Barre Scranton-Knoxville McGhee Tyson flight deals.
Search Deals
Provider most trusted by Cheapflights users for Wilkes-Barre Scranton-Knoxville McGhee Tyson flights.
Search Deals
From Wilkes-Barre to Knoxville McGhee Tyson
Search Deals
One-way flight from Wilkes-Barre to Knoxville McGhee Tyson
Search Deals
Highest demand for flights based on searches. 34% potential increase in price ($244 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 6% potential price decrease ($28 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in March 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Wilkes-Barre to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 17, 2026.
Use the filters below to find and compare flights from Wilkes-Barre to Knoxville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip
Quickest round-trip

ScrantonKnoxville

AVP - TYS

AVPTYS

Wilkes-Barre Scranton

Sat 8/22

2:29 pm-8:48 pm

1 stop6h 19m

Knoxville McGhee Tyson

Wed 8/26

5:45 am-9:40 am

1 stop3h 55m

$379
Cheapest one-way
Quickest one-way

ScrantonKnoxville

AVP - TYS

AVPTYS

Wilkes-Barre Scranton

Tue 3/31

6:00 am-10:50 am

1 stop4h 50m

$364

ScrantonKnoxville

AVP - TYS

AVPTYS

Wilkes-Barre Scranton

Fri 9/11

3:10 pm-9:30 pm

2 stops30h 20m

$402

ScrantonKnoxville

AVP - TYS

AVPTYS

Wilkes-Barre Scranton

Mon 3/30

3:25 pm-3:09 pm

2 stops23h 44m

$583

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/14

Sorted by cheapest first

Best time to book a flight from Wilkes-Barre to Knoxville

Have a flexible travel schedule? Discover the best time to fly to Knoxville from Wilkes-Barre with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Wilkes-Barre to Knoxville

What is the cheapest month to book a flight from Wilkes-Barre to Knoxville?

Currently, June is the cheapest month in which you can book a flight from Wilkes-Barre to Knoxville (average of $117). Flying from Wilkes-Barre to Knoxville in November is currently the most expensive (average of $366). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Knoxville

Get insights into the airlines that provide service to Knoxville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Knoxville. Reviews last updated March 17, 2026.
Peruse reviews from past customers who have flown with United Airlines from Wilkes-Barre to Knoxville to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
United Airlines
7.4
Good
9,431 reviews

Crew

8.1

Food

6.6

Overall

7.4

Comfort

7.3

Boarding

7.7

Entertainment

7.1

Reviews

1 / 20
10.0
Excellent

Dane,Jan 2026

TYS - IAD

It was a short flight, so no time for amenities. Just glad everything was quick and easy from boarding to arriving at my destination with my family
United Airlines
7.4
Good
9,431 reviews
United Airlines
7.4
Good
9,431 reviews

Crew

8.1

Food

6.6

Overall

7.4

Comfort

7.3

Boarding

7.7

Entertainment

7.1

Reviews

1 / 20
10.0
Excellent

Dane,Jan 2026

TYS - IAD

It was a short flight, so no time for amenities. Just glad everything was quick and easy from boarding to arriving at my destination with my family

Related info for your journey

Find useful and relevant information for your journey from Wilkes-Barre to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Knoxville from Wilkes-Barre?

    Knoxville McGhee Tyson (TYS) is the airport you will fly into if you book a flight from Wilkes-Barre to Knoxville. You should not have trouble finding flights to McGhee Tyson from Wilkes-Barre; the airport handles an average of 0 inbound flights from Wilkes-Barre per day. You should also have plenty of airline options to choose from since 4 airlines have flights to the Knoxville airport from Wilkes-Barre. It is only a 11.3 mi journey from McGhee Tyson (TYS) to Knoxville’s city center.

  • How long is the flight from Wilkes-Barre to Knoxville?

    For as low as $379, United Airlines can have you in Knoxville from Wilkes-Barre in 6h 19m. Wilkes-Barre and Knoxville are separated by a distance of 587 mi.

  • Can I find deals for flights from Wilkes-Barre to Knoxville that include hotel bookings?

    Yes. In addition to deals on Wilkes-Barre to Knoxville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Wilkes-Barre to Knoxville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Wilkes-Barre to Knoxville.

  • Can I find deals for business class flights from Wilkes-Barre to Knoxville?

    Yes. Cheapflights offers flight deals from Wilkes-Barre to Knoxville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Wilkes-Barre to Knoxville?

    Currently, June is the cheapest month in which you can book a flight from Wilkes-Barre to Knoxville (average of $117). Flying from Wilkes-Barre to Knoxville in November is currently the most expensive (average of $366). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Cherokee
Crossville
Corbin
Morristown
Bryson City
Alcoa
Murphy
Oak Ridge

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Top 4 airlines flying from Wilkes-Barre to Knoxville

Discover the top 4 airlines that operate flights from Wilkes-Barre to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 17, 2026.
AirlineCheapestAverageFlexibilityOn-time
Allegiant AirCheapest$95Average$255FlexibilityNo cancel feeOn-time88%
United AirlinesCheapest$248Average$481FlexibilityNo cancel feeOn-time69%
DeltaCheapest$268Average$501FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$358Average$557FlexibilityNo cancel feeOn-time71%

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