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Knoxville

$260+ Cheap flights from Wilkes-Barre, PA to Knoxville (TYS)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/22. Fares are subject to change and may not be available on all flights or dates of travel.
ABE — TYS
Jan 14 — Jan 211
Wed 1/14
Wed 1/21
1 adult, Economy
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Cheap flight deals from Wilkes-Barre to Knoxville

Best flights from Wilkes-Barre to Knoxville
Discover carefully curated flight deals from Wilkes-Barre to Knoxville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated December 15, 2025.

This United Airlines deal was found by Cheapflights users on 12/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/3010:35 amAVP - TYS
2 stops10h 17mUnited Airlines
Mon 2/26:45 amTYS - AVP
2 stops12h 00mUnited Airlines
Deal found 12/13$349
This American Airlines deal was found by Cheapflights users on 12/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/237:28 amAVP - TYS
1 stop14h 41mAmerican Airlines
Mon 1/267:54 amTYS - AVP
1 stop12h 04mAmerican Airlines
Deal found 12/14$387
This United Airlines deal was found by Cheapflights users on 12/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/317:45 pmAVP - TYS
1 stop15h 12mUnited Airlines
Tue 2/31:59 pmTYS - AVP
1 stop7h 01mUnited Airlines
Deal found 12/13$408
This United Airlines deal was found by Cheapflights users on 12/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/317:45 pmAVP - TYS
1 stop19h 04mUnited Airlines
Wed 2/42:25 pmTYS - AVP
1 stop4h 20mUnited Airlines
Deal found 12/12$408
This United Airlines deal was found by Cheapflights users on 12/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/2310:35 amAVP - TYS
2 stops10h 17mUnited Airlines
Mon 1/267:20 pmTYS - AVP
1 stop14h 27mUnited Airlines
Deal found 12/14$413

Find flight deals from Wilkes-Barre to Knoxville

Keep the following information in mind while searching for Wilkes-Barre to Knoxville flight deals. Data was last updated December 15, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$349
(United Airlines)

One-way from

$260
(Kiwi.com)

Popular in

October

Cheapest in

January

Average price

$477
Provider with most accurate pricing for Wilkes-Barre Scranton-Knoxville McGhee Tyson flight deals.
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Provider most trusted by Cheapflights users for Wilkes-Barre Scranton-Knoxville McGhee Tyson flights.
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From Wilkes-Barre to Knoxville McGhee Tyson
Search Deals
One-way flight from Wilkes-Barre to Knoxville McGhee Tyson
Search Deals
Highest demand for flights based on searches. 22% potential increase in price ($136 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 3% potential price decrease ($16 potential savings vs. average RT price).
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Average for round-trip flights in December 2025
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Wilkes-Barre to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 15, 2025.
Use the filters below to find and compare flights from Wilkes-Barre to Knoxville that are best for you.

Fly from

Wilkes-Barre

Fly to

Knoxville

Route

Depart

Return

Price

ScrantonKnoxville

AVP - TYS

AVPTYS

Wilkes-Barre Scranton

Fri 1/30

10:35 am-8:52 pm

2 stops10h 17m

Knoxville McGhee Tyson

Mon 2/2

6:45 am-6:45 pm

2 stops12h 00m

$349

ScrantonKnoxville

AVP - TYS

AVPTYS

Wilkes-Barre Scranton

Fri 1/23

7:28 am-10:09 pm

1 stop14h 41m

Knoxville McGhee Tyson

Mon 1/26

7:54 am-7:58 pm

1 stop12h 04m

$387

ScrantonKnoxville

AVP - TYS

AVPTYS

Wilkes-Barre Scranton

Sat 1/31

7:45 pm-10:57 am

1 stop15h 12m

Knoxville McGhee Tyson

Tue 2/3

1:59 pm-9:00 pm

1 stop7h 01m

$408

ScrantonKnoxville

AVP - TYS

AVPTYS

Wilkes-Barre Scranton

Sat 1/31

7:45 pm-2:49 pm

1 stop19h 04m

Knoxville McGhee Tyson

Wed 2/4

2:25 pm-6:45 pm

1 stop4h 20m

$408

ScrantonKnoxville

AVP - TYS

AVPTYS

Wilkes-Barre Scranton

Fri 1/23

10:35 am-8:52 pm

2 stops10h 17m

Knoxville McGhee Tyson

Mon 1/26

7:20 pm-9:47 am

1 stop14h 27m

$413

ScrantonKnoxville

AVP - TYS

AVPTYS

Wilkes-Barre Scranton

Mon 12/22

7:36 pm-4:15 pm

2 stops44h 39m

$260

ScrantonKnoxville

AVP - TYS

AVPTYS

Wilkes-Barre Scranton

Sat 12/20

2:39 pm-9:56 pm

2 stops31h 17m

$278

ScrantonKnoxville

AVP - TYS

AVPTYS

Wilkes-Barre Scranton

Mon 12/22

7:45 pm-11:59 pm

1 stop4h 14m

$390

ScrantonKnoxville

AVP - TYS

AVPTYS

Wilkes-Barre Scranton

Sat 12/20

5:16 pm-10:39 pm

1 stop5h 23m

$390

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/13

Best time to book a flight from Wilkes-Barre to Knoxville

Have a flexible travel schedule? Discover the best time to fly to Knoxville from Wilkes-Barre with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Wilkes-Barre to Knoxville

What is the cheapest month to book a flight from Wilkes-Barre to Knoxville?

Currently, June is the cheapest month in which you can book a flight from Wilkes-Barre to Knoxville (average of $167). Flying from Wilkes-Barre to Knoxville in November is currently the most expensive (average of $334). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from W1L to TYS?

Find hourly flight availability from Wilkes-Barre to Knoxville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 15, 2025.

A simple way to save on the total cost of your ticket is to fly from Wilkes-Barre to Knoxville in the evening. If you’re flexible enough to do this you can expect to save up to 32% on your trip compared to booking a flight in the afternoon.

Reviews of airlines servicing Knoxville

Get insights into the airlines that provide service to Knoxville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Knoxville. Reviews last updated December 15, 2025.
Peruse reviews from past customers who have flown with United Airlines and American Airlines from Wilkes-Barre to Knoxville to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
United Airlines
7.4
Good
9,092 reviews

Overall

7.4

Boarding

7.7

Food

6.6

Entertainment

7.1

Crew

8.1

Comfort

7.3

Reviews

1 / 20
10.0
Excellent

Sunderesh,Dec 2025

AUS - EWR

Smooth flight from Austin to Newark. The crew was friendly.
United Airlines
7.4
Good
9,092 reviews
United Airlines
7.4
Good
9,092 reviews

Overall

7.4

Boarding

7.7

Food

6.6

Entertainment

7.1

Crew

8.1

Comfort

7.3

Reviews

1 / 20
10.0
Excellent

Sunderesh,Dec 2025

AUS - EWR

Smooth flight from Austin to Newark. The crew was friendly.
American Airlines
7.2
Good
11,052 reviews
United Airlines
7.4
Good
9,092 reviews

Overall

7.4

Boarding

7.7

Food

6.6

Entertainment

7.1

Crew

8.1

Comfort

7.3

Reviews

1 / 20
10.0
Excellent

Sunderesh,Dec 2025

AUS - EWR

Smooth flight from Austin to Newark. The crew was friendly.

Related info for your journey

Find useful and relevant information for your journey from Wilkes-Barre to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Knoxville from Wilkes-Barre?

    Knoxville McGhee Tyson (TYS) is the airport you will fly into if you book a flight from Wilkes-Barre to Knoxville. You should not have trouble finding flights to McGhee Tyson from Wilkes-Barre; the airport handles an average of 0 inbound flights from Wilkes-Barre per day. You should also have plenty of airline options to choose from since 4 airlines have flights to the Knoxville airport from Wilkes-Barre. It is only a 11.3 mi journey from McGhee Tyson (TYS) to Knoxville’s city center.

  • How long is the flight from Wilkes-Barre to Knoxville?

    For as low as $349, United Airlines can have you in Knoxville from Wilkes-Barre in 10h 17m. Wilkes-Barre and Knoxville are separated by a distance of 587 mi. This flight may include one or multiple stops.

  • Can I find deals for flights from Wilkes-Barre to Knoxville that include hotel bookings?

    Yes. In addition to deals on Wilkes-Barre to Knoxville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Wilkes-Barre to Knoxville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Wilkes-Barre to Knoxville.

  • Can I find deals for business class flights from Wilkes-Barre to Knoxville?

    Yes. Cheapflights offers flight deals from Wilkes-Barre to Knoxville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Wilkes-Barre to Knoxville?

    Currently, June is the cheapest month in which you can book a flight from Wilkes-Barre to Knoxville (average of $167). Flying from Wilkes-Barre to Knoxville in November is currently the most expensive (average of $334). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Cherokee
Crossville
Corbin
Morristown
Bryson City
Alcoa
Oak Ridge
Murphy

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Top 4 airlines flying from Wilkes-Barre to Knoxville

Discover the top 4 airlines that operate flights from Wilkes-Barre to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 15, 2025.
AirlineCheapestAverageFlexibilityOn-time
Allegiant AirCheapest$141Average$254FlexibilityNo cancel feeOn-time88%
United AirlinesCheapest$248Average$493FlexibilityNo cancel feeOn-time69%
DeltaCheapest$278Average$498FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$351Average$516FlexibilityNo cancel feeOn-time71%

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