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$219+ Cheap flights from Wilkes-Barre, PA to Knoxville (TYS)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/22. Fares are subject to change and may not be available on all flights or dates of travel.
ABE — TYS
Oct 11 — Oct 181
Sat 10/11
Sat 10/18
1 adult, Economy
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Cheap flight deals from Wilkes-Barre to Knoxville

Keep the following information in mind while searching for Wilkes-Barre to Knoxville flight deals. Data was last updated September 11, 2025.

Round-trip from

$249
(United Airlines)

One-way from

$219
(Kiwi.com)

Popular in

September

Cheapest in

January

Average price

$828
From Wilkes-Barre to Knoxville McGhee Tyson
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One-way flight from Wilkes-Barre to Knoxville McGhee Tyson
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Highest demand for flights based on searches. 9% potential increase in price ($51 potential increase over avg. RT price).
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Cheapest flight prices on average. 6% potential price decrease ($31 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Find flight deals from Wilkes-Barre to Knoxville

Cheapest flights from Wilkes-Barre to Knoxville
Explore the most affordable flight options available from Wilkes-Barre to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 11, 2025.

This United Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/57:45 pmAVP - TYS
1 stop4h 14mUnited Airlines
Wed 11/125:45 amTYS - AVP
1 stop4h 01mUnited Airlines
Deal found 9/9$249
This United Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/255:31 pmAVP - TYS
1 stop5h 19mUnited Airlines
Mon 9/2910:51 amTYS - AVP
1 stop6h 05mUnited Airlines
Deal found 9/10$259
This United Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/47:45 pmAVP - TYS
1 stop4h 14mUnited Airlines
Tue 11/115:45 amTYS - AVP
1 stop4h 01mUnited Airlines
Deal found 9/9$291
This United Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/223:32 pmAVP - TYS
1 stop18h 33mUnited Airlines
Sun 11/309:50 amTYS - AVP
1 stop23h 56mUnited Airlines
Deal found 9/11$497
This United Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/77:45 pmAVP - TYS
2 stops24h 48mUnited Airlines
Fri 11/149:50 amTYS - AVP
1 stop23h 56mUnited Airlines
Deal found 9/9$542
This American Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/76:00 amAVP - TYS
1 stop5h 31mAmerican Airlines
Fri 11/147:20 pmTYS - AVP
1 stop3h 50mAmerican Airlines
Deal found 9/9$561

Cheapflights Fare Finder

 
Customize your flight search to find flights from Wilkes-Barre to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 11, 2025.
Use the filters below to find and compare flights from Wilkes-Barre to Knoxville that are best for you.

Fly from

Wilkes-Barre

Fly to

Knoxville

Route

Depart

Return

Price

ScrantonKnoxville

AVP - TYS

AVPTYS

Wilkes-Barre Scranton

Wed 11/5

7:45 pm-11:59 pm

1 stop4h 14m

Knoxville McGhee Tyson

Wed 11/12

5:45 am-9:46 am

1 stop4h 01m

$249

ScrantonKnoxville

AVP - TYS

AVPTYS

Wilkes-Barre Scranton

Thu 9/25

5:31 pm-10:50 pm

1 stop5h 19m

Knoxville McGhee Tyson

Mon 9/29

10:51 am-4:56 pm

1 stop6h 05m

$259

ScrantonKnoxville

AVP - TYS

AVPTYS

Wilkes-Barre Scranton

Tue 11/4

7:45 pm-11:59 pm

1 stop4h 14m

Knoxville McGhee Tyson

Tue 11/11

5:45 am-9:46 am

1 stop4h 01m

$291

ScrantonKnoxville

AVP - TYS

AVPTYS

Wilkes-Barre Scranton

Sat 2/7

10:35 am-2:54 pm

1 stop4h 19m

Knoxville McGhee Tyson

Sat 2/14

2:55 pm-6:48 pm

1 stop3h 53m

$319

ScrantonKnoxville

AVP - TYS

AVPTYS

Wilkes-Barre Scranton

Sat 3/7

2:45 pm-8:45 am

1 stop18h 00m

Knoxville McGhee Tyson

Wed 3/11

2:00 pm-8:42 pm

1 stop6h 42m

$443

ScrantonKnoxville

AVP - TYS

AVPTYS

Wilkes-Barre Scranton

Sat 3/7

12:13 pm-5:31 pm

1 stop5h 18m

Knoxville McGhee Tyson

Tue 3/10

11:45 am-4:01 pm

1 stop4h 16m

$445

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/9

Best time to book a flight from Wilkes-Barre to Knoxville

Have a flexible travel schedule? Discover the best time to fly to Knoxville from Wilkes-Barre with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Wilkes-Barre to Knoxville

What is the cheapest month to book a flight from Wilkes-Barre to Knoxville?

Currently, January is the cheapest month in which you can book a flight from Wilkes-Barre to Knoxville (average of $294). Flying from Wilkes-Barre to Knoxville in March is currently the most expensive (average of $376). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from W1L to TYS?

Find hourly flight availability from Wilkes-Barre to Knoxville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 11, 2025.

When flying from Wilkes-Barre to Knoxville, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Reviews of airlines servicing Knoxville

Get insights into the airlines that provide service to Knoxville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Knoxville. Reviews last updated September 11, 2025.
Peruse reviews from past customers who have flown with United Airlines and American Airlines from Wilkes-Barre to Knoxville to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
United Airlines
7.4
Good
8,937 reviews

Boarding

7.7

Food

6.6

Comfort

7.3

Entertainment

7.1

Overall

7.4

Crew

8.1

Reviews

1 / 20
2.0
Mediocre

Deb,Jan 2025

MKE - ORD

It was terrible! So much to say, but in a nutshell we used vouchers from United because our last trip with them was awful with many mishaps and errors made. Unfortunately, this trip was even worse!
United Airlines
7.4
Good
8,937 reviews
United Airlines
7.4
Good
8,937 reviews

Boarding

7.7

Food

6.6

Comfort

7.3

Entertainment

7.1

Overall

7.4

Crew

8.1

Reviews

1 / 20
2.0
Mediocre

Deb,Jan 2025

MKE - ORD

It was terrible! So much to say, but in a nutshell we used vouchers from United because our last trip with them was awful with many mishaps and errors made. Unfortunately, this trip was even worse!
American Airlines
7.2
Good
10,000 reviews
United Airlines
7.4
Good
8,937 reviews

Boarding

7.7

Food

6.6

Comfort

7.3

Entertainment

7.1

Overall

7.4

Crew

8.1

Reviews

1 / 20
2.0
Mediocre

Deb,Jan 2025

MKE - ORD

It was terrible! So much to say, but in a nutshell we used vouchers from United because our last trip with them was awful with many mishaps and errors made. Unfortunately, this trip was even worse!

Related info for your journey

Find useful and relevant information for your journey from Wilkes-Barre to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Knoxville from Wilkes-Barre?

    Knoxville McGhee Tyson (TYS) is the airport you will fly into if you book a flight from Wilkes-Barre to Knoxville. You should not have trouble finding flights to McGhee Tyson from Wilkes-Barre; the airport handles an average of 0 inbound flights from Wilkes-Barre per day. You should also have plenty of airline options to choose from since 4 airlines have flights to the Knoxville airport from Wilkes-Barre. It is only a 11.3 mi journey from McGhee Tyson (TYS) to Knoxville’s city center.

  • How long is the flight from Wilkes-Barre to Knoxville?

    For as low as $249, United Airlines can have you in Knoxville from Wilkes-Barre in 4h 14m. Wilkes-Barre and Knoxville are separated by a distance of 587 mi.

  • Can I find deals for flights from Wilkes-Barre to Knoxville that include hotel bookings?

    Yes. In addition to deals on Wilkes-Barre to Knoxville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Wilkes-Barre to Knoxville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Wilkes-Barre to Knoxville.

  • Can I find deals for business class flights from Wilkes-Barre to Knoxville?

    Yes. Cheapflights offers flight deals from Wilkes-Barre to Knoxville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Wilkes-Barre to Knoxville?

    Currently, January is the cheapest month in which you can book a flight from Wilkes-Barre to Knoxville (average of $294). Flying from Wilkes-Barre to Knoxville in March is currently the most expensive (average of $376). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Morristown
Cherokee
Corbin
Alcoa
Oak Ridge
Murphy

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Top 4 airlines flying from Wilkes-Barre to Knoxville

Discover the top 4 airlines that operate flights from Wilkes-Barre to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 11, 2025.
AirlineCheapestAverageFlexibilityOn-time
Allegiant AirCheapest$141Average$255FlexibilityNo cancel feeOn-time88%
United AirlinesCheapest$248Average$493FlexibilityNo cancel feeOn-time69%
DeltaCheapest$278Average$501FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$351Average$509FlexibilityNo cancel feeOn-time71%

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