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$315+ Cheap flights from Wilkes-Barre, PA to Knoxville (TYS)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/5. Fares are subject to change and may not be available on all flights or dates of travel.
ABE — TYS
Feb 28 — Mar 71
Sat 2/28
Sat 3/7
1 adult, Economy
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Cheap flight deals from Wilkes-Barre to Knoxville

Cheapest flights from Wilkes-Barre to Knoxville
Explore the most affordable flight options available from Wilkes-Barre to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 29, 2026.

This United Airlines deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/1410:30 am
AVP
-
TYS
1 stop4h 39m
United Airlines
Mon 4/207:20 pm
TYS
-
AVP
1 stop4h 24m
United Airlines
Deal found 1/28$360
This United Airlines deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/316:24 am
AVP
-
TYS
1 stop7h 00m
United Airlines
Mon 2/21:59 pm
TYS
-
AVP
1 stop7h 01m
United Airlines
Deal found 1/28$369
This United Airlines deal was found by Cheapflights users on 1/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/137:45 pm
AVP
-
TYS
1 stop15h 04m
United Airlines
Tue 2/176:45 am
TYS
-
AVP
1 stop6h 52m
United Airlines
Deal found 1/29$413
This United Airlines deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/310:00 am
AVP
-
TYS
1 stop6h 48m
United Airlines
Sat 2/71:59 pm
TYS
-
AVP
1 stop7h 01m
United Airlines
Deal found 1/28$424
This American Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/245:43 pm
AVP
-
TYS
1 stop6h 27m
American Airlines
Mon 9/284:01 pm
TYS
-
AVP
1 stop6h 16m
American Airlines
Deal found 1/27$460

Find flight deals from Wilkes-Barre to Knoxville

Keep the following information in mind while searching for Wilkes-Barre to Knoxville flight deals. Data was last updated January 29, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$484
(United Airlines)

One-way from

$315
(Kiwi.com)

Popular in

October

Cheapest in

February

Average price

$491
Provider with most accurate pricing for Wilkes-Barre Scranton-Knoxville McGhee Tyson flight deals.
Search Deals
Provider most trusted by Cheapflights users for Wilkes-Barre Scranton-Knoxville McGhee Tyson flights.
Search Deals
From Wilkes-Barre to Knoxville McGhee Tyson
Search Deals
One-way flight from Wilkes-Barre to Knoxville McGhee Tyson
Search Deals
Highest demand for flights based on searches. 18% potential increase in price ($111 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($13 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in January 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Wilkes-Barre to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 29, 2026.
Use the filters below to find and compare flights from Wilkes-Barre to Knoxville that are best for you.

Fly from

Wilkes-Barre

Fly to

Knoxville

Route

Depart

Return

Price

ScrantonKnoxville

AVP - TYS

AVPTYS

Wilkes-Barre Scranton

Tue 4/14

10:30 am-3:09 pm

1 stop4h 39m

Knoxville McGhee Tyson

Mon 4/20

7:20 pm-11:44 pm

1 stop4h 24m

$360

ScrantonKnoxville

AVP - TYS

AVPTYS

Wilkes-Barre Scranton

Fri 2/13

7:45 pm-8:37 pm

2 stops24h 52m

Knoxville McGhee Tyson

Tue 2/17

6:45 am-1:37 pm

1 stop6h 52m

$473

ScrantonKnoxville

AVP - TYS

AVPTYS

Wilkes-Barre Scranton

Fri 3/6

7:44 pm-10:49 am

1 stop15h 05m

Knoxville McGhee Tyson

Mon 3/16

7:25 pm-6:27 pm

1 stop23h 02m

$484

ScrantonKnoxville

AVP - TYS

AVPTYS

Wilkes-Barre Scranton

Fri 6/5

5:09 pm-11:49 pm

1 stop6h 40m

Knoxville McGhee Tyson

Sun 6/7

6:33 pm-11:59 pm

1 stop5h 26m

$539

ScrantonKnoxville

AVP - TYS

AVPTYS

Wilkes-Barre Scranton

Fri 3/6

7:28 am-4:31 pm

1 stop9h 03m

Knoxville McGhee Tyson

Mon 3/16

11:42 am-10:46 pm

1 stop11h 04m

$601

ScrantonKnoxville

AVP - TYS

AVPTYS

Wilkes-Barre Scranton

Sun 3/1

7:28 am-8:40 pm

1 stop13h 12m

Knoxville McGhee Tyson

Wed 3/4

11:42 am-10:46 pm

1 stop11h 04m

$615

ScrantonKnoxville

AVP - TYS

AVPTYS

Wilkes-Barre Scranton

Sun 2/15

2:12 pm-8:37 pm

1 stop6h 25m

Knoxville McGhee Tyson

Wed 2/18

6:45 am-1:37 pm

1 stop6h 52m

$615

ScrantonKnoxville

AVP - TYS

AVPTYS

Wilkes-Barre Scranton

Mon 2/16

10:35 am-3:15 pm

1 stop4h 40m

Knoxville McGhee Tyson

Wed 2/18

6:45 am-1:37 pm

1 stop6h 52m

$615

ScrantonKnoxville

AVP - TYS

AVPTYS

Wilkes-Barre Scranton

Thu 2/5

9:23 am-7:56 pm

2 stops34h 33m

$315

ScrantonKnoxville

AVP - TYS

AVPTYS

Wilkes-Barre Scranton

Mon 2/16

10:35 am-3:15 pm

1 stop4h 40m

$332

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/28

Showing 1-10 of 11 results
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Best time to book a flight from Wilkes-Barre to Knoxville

Have a flexible travel schedule? Discover the best time to fly to Knoxville from Wilkes-Barre with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Wilkes-Barre to Knoxville

What is the cheapest month to book a flight from Wilkes-Barre to Knoxville?

Currently, June is the cheapest month in which you can book a flight from Wilkes-Barre to Knoxville (average of $167). Flying from Wilkes-Barre to Knoxville in November is currently the most expensive (average of $334). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Knoxville

Get insights into the airlines that provide service to Knoxville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Knoxville. Reviews last updated January 29, 2026.
Peruse reviews from past customers who have flown with United Airlines and American Airlines from Wilkes-Barre to Knoxville to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
United Airlines
7.4
Good
9,214 reviews

Food

6.6

Overall

7.4

Crew

8.1

Boarding

7.7

Comfort

7.3

Entertainment

7.1

Reviews

1 / 20
10.0
Excellent

Dane,Jan 2026

TYS - IAD

It was a short flight, so no time for amenities. Just glad everything was quick and easy from boarding to arriving at my destination with my family
United Airlines
7.4
Good
9,214 reviews
United Airlines
7.4
Good
9,214 reviews

Food

6.6

Overall

7.4

Crew

8.1

Boarding

7.7

Comfort

7.3

Entertainment

7.1

Reviews

1 / 20
10.0
Excellent

Dane,Jan 2026

TYS - IAD

It was a short flight, so no time for amenities. Just glad everything was quick and easy from boarding to arriving at my destination with my family
American Airlines
7.2
Good
11,205 reviews
United Airlines
7.4
Good
9,214 reviews

Food

6.6

Overall

7.4

Crew

8.1

Boarding

7.7

Comfort

7.3

Entertainment

7.1

Reviews

1 / 20
10.0
Excellent

Dane,Jan 2026

TYS - IAD

It was a short flight, so no time for amenities. Just glad everything was quick and easy from boarding to arriving at my destination with my family

Related info for your journey

Find useful and relevant information for your journey from Wilkes-Barre to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Knoxville from Wilkes-Barre?

    Knoxville McGhee Tyson (TYS) is the airport you will fly into if you book a flight from Wilkes-Barre to Knoxville. You should not have trouble finding flights to McGhee Tyson from Wilkes-Barre; the airport handles an average of 0 inbound flights from Wilkes-Barre per day. You should also have plenty of airline options to choose from since 4 airlines have flights to the Knoxville airport from Wilkes-Barre. It is only a 11.3 mi journey from McGhee Tyson (TYS) to Knoxville’s city center.

  • How long is the flight from Wilkes-Barre to Knoxville?

    For as low as $360, United Airlines can have you in Knoxville from Wilkes-Barre in 4h 39m. Wilkes-Barre and Knoxville are separated by a distance of 587 mi.

  • Can I find deals for flights from Wilkes-Barre to Knoxville that include hotel bookings?

    Yes. In addition to deals on Wilkes-Barre to Knoxville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Wilkes-Barre to Knoxville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Wilkes-Barre to Knoxville.

  • Can I find deals for business class flights from Wilkes-Barre to Knoxville?

    Yes. Cheapflights offers flight deals from Wilkes-Barre to Knoxville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Wilkes-Barre to Knoxville?

    Currently, June is the cheapest month in which you can book a flight from Wilkes-Barre to Knoxville (average of $167). Flying from Wilkes-Barre to Knoxville in November is currently the most expensive (average of $334). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Cherokee
Crossville
Corbin
Morristown
Bryson City
Alcoa
Oak Ridge
Murphy

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Alternative routes for Wilkes-Barre to Knoxville

See prices for flight routes from nearby airports that may be better suited for you.
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Top 4 airlines flying from Wilkes-Barre to Knoxville

Discover the top 4 airlines that operate flights from Wilkes-Barre to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 29, 2026.
AirlineCheapestAverageFlexibilityOn-time
Allegiant AirCheapest$95Average$254FlexibilityNo cancel feeOn-time88%
DeltaCheapest$238Average$473FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$248Average$493FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$351Average$529FlexibilityNo cancel feeOn-time71%

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