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$515+ Cheap flights from San Luis Potosí, Mexico (SLP) to Knoxville (TYS)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/28. Fares are subject to change and may not be available on all flights or dates of travel.
SLP — TYS
Mar 16 — Mar 231
Mon 3/16
Mon 3/23
1 adult, Economy
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Cheap flight deals from San Luis Potosí to Knoxville

Cheapest flights from San Luis Potosí to Knoxville
Explore the most affordable flight options available from San Luis Potosí to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 14, 2026.

This United Airlines deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/2811:51 am
SLP
-
TYS
2 stops20h 09m
United Airlines
Tue 9/17:00 am
TYS
-
SLP
2 stops14h 12m
United Airlines
Deal found 2/10$515
This United Airlines deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/212:49 pm
SLP
-
TYS
1 stop23h 57m
United Airlines
Fri 3/67:00 am
TYS
-
SLP
2 stops29h 49m
United Airlines
Deal found 2/11$633
This Delta deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/28:24 am
SLP
-
TYS
1 stop5h 51m
Delta
Fri 3/65:35 am
TYS
-
SLP
1 stop13h 45m
Delta
Deal found 2/11$752

Find flight deals from San Luis Potosí to Knoxville

Discover tips and strategies to find the most affordable flight options for your journey from San Luis Potosí (SLP) to Knoxville (TYS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated February 14, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$633
(United Airlines)
Provider with most accurate pricing for San Luis Potosi-Knoxville McGhee Tyson flight deals.
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Provider most trusted by Cheapflights users for San Luis Potosi-Knoxville McGhee Tyson flights.
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From San Luis Potosi to Knoxville McGhee Tyson
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Cheapflights Fare Finder

 
Customize your flight search to find flights from San Luis Potosí to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 14, 2026.
Use the filters below to find and compare flights from San Luis Potosí to Knoxville that are best for you.

Fly from

San Luis Potosí

Fly to

Knoxville

Route

Depart

Return

Price

San Luis PotosíKnoxville

SLP - TYS

SLPTYS

San Luis Potosi

Mon 3/2

12:49 pm-1:46 pm

1 stop23h 57m

Knoxville McGhee Tyson

Fri 3/6

7:00 am-11:49 am

2 stops29h 49m

$633

San Luis PotosíKnoxville

SLP - TYS

SLPTYS

San Luis Potosi

Mon 3/2

8:24 am-3:15 pm

1 stop5h 51m

Knoxville McGhee Tyson

Fri 3/6

5:35 am-6:20 pm

1 stop13h 45m

$752

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/11

  • Most accurate provider: When it comes to deals on San Luis Potosí-Knoxville flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on San Luis Potosí-Knoxville flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from San Luis Potosí-Knoxville flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on San Luis Potosí-Knoxville flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for San Luis Potosí-Knoxville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from San Luis Potosí to Knoxville

Have a flexible travel schedule? Discover the best time to fly to Knoxville from San Luis Potosí with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Related info for your journey

Find useful and relevant information for your journey from San Luis Potosí to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from San Luis Potosí to Knoxville?

    For as low as $752, United Airlines can have you in Knoxville from San Luis Potosí in 5h 51m. There are 1382 mi between San Luis Potosí and Knoxville. Both multi-stop and nonstop flights can be found to your destination and back.

  • Can I find deals for flights from San Luis Potosí to Knoxville that include hotel bookings?

    Yes. In addition to deals on San Luis Potosí to Knoxville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from San Luis Potosí to Knoxville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from San Luis Potosí to Knoxville.

  • Can I find deals for business class flights from San Luis Potosí to Knoxville?

    Yes. Cheapflights offers flight deals from San Luis Potosí to Knoxville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Traveling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Cherokee
Crossville
Corbin
Morristown
Bryson City
Alcoa
Oak Ridge
Murphy

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