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$434+ Cheap flights from San Luis Potosí, Mexico (SLP) to Knoxville (TYS)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/16. Fares are subject to change and may not be available on all flights or dates of travel.
SLP — TYS
Aug 25 — Sep 11
Mon 8/25
Mon 9/1
1 adult, Economy
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Cheap flight deals from San Luis Potosí to Knoxville

Discover tips and strategies to find the most affordable flight options for your journey from San Luis Potosí (SLP) to Knoxville (TYS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated August 20, 2025.

Round-trip from

$434
(Delta)
From San Luis Potosi to Knoxville McGhee Tyson
Search Deals

Find flight deals from San Luis Potosí to Knoxville

Cheapest flights from San Luis Potosí to Knoxville
Explore the most affordable flight options available from San Luis Potosí to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 20, 2025.

This United Airlines deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/176:00 amSLP - TYS
2 stops12h 29mUnited Airlines
Wed 1/75:50 amTYS - SLP
2 stops15h 25mUnited Airlines
Deal found 8/19$434
This United Airlines deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/1512:49 pmSLP - TYS
2 stops20h 24mUnited Airlines
Thu 1/812:00 pmTYS - SLP
1 stop9h 15mUnited Airlines
Deal found 8/20$435
This United Airlines deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/1612:49 pmSLP - TYS
1 stop9h 55mUnited Airlines
Tue 1/62:00 pmTYS - SLP
2 stops22h 49mUnited Airlines
Deal found 8/18$436
This Delta deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/178:28 amSLP - TYS
1 stop7h 49mDelta
Wed 1/72:30 pmTYS - SLP
2 stops10h 47mDelta
Deal found 8/18$437
This American Airlines deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/176:24 amSLP - TYS
1 stop9h 57mAmerican Airlines
Tue 1/64:27 pmTYS - SLP
1 stop7h 33mAmerican Airlines
Deal found 8/18$446
This Delta deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/148:28 amSLP - TYS
1 stop5h 37mDelta
Wed 1/712:00 pmTYS - SLP
1 stop6h 49mDelta
Deal found 8/19$455
This United Airlines deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/146:00 amSLP - TYS
1 stop6h 49mUnited Airlines
Mon 1/55:45 amTYS - SLP
2 stops16h 09mUnited Airlines
Deal found 8/20$456
This Delta deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/138:28 amSLP - TYS
1 stop5h 37mDelta
Wed 1/712:00 pmTYS - SLP
1 stop6h 49mDelta
Deal found 8/18$457
This United Airlines deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/1412:49 pmSLP - TYS
2 stops20h 24mUnited Airlines
Sun 1/45:45 amTYS - SLP
2 stops31h 04mUnited Airlines
Deal found 8/18$458
This United Airlines deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/186:00 amSLP - TYS
2 stops16h 59mUnited Airlines
Mon 1/129:15 amTYS - SLP
1 stop12h 00mUnited Airlines
Deal found 8/19$470
This United Airlines deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/2212:49 pmSLP - TYS
2 stops21h 07mUnited Airlines
Sun 1/45:45 amTYS - SLP
2 stops40h 09mUnited Airlines
Deal found 8/18$472

Cheapflights Fare Finder

 
Customize your flight search to find flights from San Luis Potosí to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 20, 2025.
Use the filters below to find and compare flights from San Luis Potosí to Knoxville that are best for you.

Fly from

San Luis Potosí

Fly to

Knoxville

Route

Depart

Return

Price

San Luis PotosíKnoxville

SLP - TYS

SLPTYS

San Luis Potosi

Tue 12/16

8:28 am-5:17 pm

1 stop7h 49m

Knoxville McGhee Tyson

Wed 1/7

12:00 pm-5:49 pm

1 stop6h 49m

$434

San Luis PotosíKnoxville

SLP - TYS

SLPTYS

San Luis Potosi

Wed 12/17

6:00 am-7:29 pm

2 stops12h 29m

Knoxville McGhee Tyson

Sun 1/4

5:45 am-11:49 am

2 stops31h 04m

$434

San Luis PotosíKnoxville

SLP - TYS

SLPTYS

San Luis Potosi

Thu 12/18

10:00 am-5:17 pm

1 stop6h 17m

Knoxville McGhee Tyson

Wed 1/7

10:05 am-5:49 pm

1 stop8h 44m

$434

San Luis PotosíKnoxville

SLP - TYS

SLPTYS

San Luis Potosi

Wed 12/17

6:00 am-7:29 pm

2 stops12h 29m

Knoxville McGhee Tyson

Wed 1/7

5:50 am-8:15 pm

2 stops15h 25m

$434

San Luis PotosíKnoxville

SLP - TYS

SLPTYS

San Luis Potosi

Thu 12/18

10:00 am-6:13 pm

1 stop7h 13m

Knoxville McGhee Tyson

Tue 1/6

6:10 am-11:37 pm

2 stops18h 27m

$434

San Luis PotosíKnoxville

SLP - TYS

SLPTYS

San Luis Potosi

Mon 12/15

6:00 am-7:29 pm

2 stops12h 29m

Knoxville McGhee Tyson

Tue 1/6

5:50 am-8:15 pm

2 stops15h 25m

$434

San Luis PotosíKnoxville

SLP - TYS

SLPTYS

San Luis Potosi

Wed 12/17

8:28 am-5:17 pm

1 stop7h 49m

Knoxville McGhee Tyson

Thu 1/8

7:07 am-5:49 pm

1 stop11h 42m

$434

San Luis PotosíKnoxville

SLP - TYS

SLPTYS

San Luis Potosi

Mon 12/15

12:49 pm-1:17 pm

2 stops23h 28m

Knoxville McGhee Tyson

Thu 1/8

10:16 am-8:15 pm

2 stops10h 59m

$434

San Luis PotosíKnoxville

SLP - TYS

SLPTYS

San Luis Potosi

Mon 12/15

5:52 am-11:46 pm

2 stops16h 54m

Knoxville McGhee Tyson

Tue 1/6

12:00 pm-5:49 pm

1 stop6h 49m

$434

San Luis PotosíKnoxville

SLP - TYS

SLPTYS

San Luis Potosi

Wed 12/17

6:00 am-11:44 pm

1 stop16h 44m

Knoxville McGhee Tyson

Mon 1/12

9:15 am-8:15 pm

1 stop12h 00m

$434

Flights are sorted by cheapest round-trip flights first.

Deals found on 8/19

Showing 1-10 of 11 results
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Best time to book a flight from San Luis Potosí to Knoxville

Have a flexible travel schedule? Discover the best time to fly to Knoxville from San Luis Potosí with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Related info for your journey

Find useful and relevant information for your journey from San Luis Potosí to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from San Luis Potosí to Knoxville?

    For as low as $434, Delta can have you in Knoxville from San Luis Potosí in 7h 49m. There are 1382 mi between San Luis Potosí and Knoxville. Both multi-stop and nonstop flights can be found to your destination and back.

  • Can I find deals for flights from San Luis Potosí to Knoxville that include hotel bookings?

    Yes. In addition to deals on San Luis Potosí to Knoxville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from San Luis Potosí to Knoxville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from San Luis Potosí to Knoxville.

  • Can I find deals for business class flights from San Luis Potosí to Knoxville?

    Yes. Cheapflights offers flight deals from San Luis Potosí to Knoxville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from San Luis Potosí to Knoxville?

    Currently, January is the cheapest month in which you can book a flight from San Luis Potosí to Knoxville (average of $295). Flying from San Luis Potosí to Knoxville in March is currently the most expensive (average of $376). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Morristown
Cherokee
Corbin
Alcoa
Oak Ridge
Murphy

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