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Knoxville

$294+ Cheap flights from Rochester, MN to Knoxville (RST - TYS)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/18. Fares are subject to change and may not be available on all flights or dates of travel.
RST — TYS
Apr 12 — Apr 191
Sun 4/12
Sun 4/19
1 adult, Economy
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Cheap flight deals from Rochester to Knoxville

Cheapest flights from Rochester to Knoxville
Explore the most affordable flight options available from Rochester to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 13, 2026.

This Delta deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/34:46 pm
RST
-
TYS
1 stop5h 17m
Delta
Fri 4/106:35 am
TYS
-
RST
1 stop5h 15m
Delta
Deal found 3/11$298
This American Airlines deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/145:40 am
RST
-
TYS
2 stops8h 46m
American Airlines
Sat 4/184:09 pm
TYS
-
RST
2 stops8h 46m
American Airlines
Deal found 3/12$309
This Delta deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/244:46 pm
RST
-
TYS
1 stop5h 17m
Delta
Sat 3/286:35 am
TYS
-
RST
1 stop5h 15m
Delta
Deal found 3/9$318
This United Airlines deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/111:28 am
RST
-
TYS
1 stop4h 31m
United Airlines
Sat 9/56:30 am
TYS
-
RST
1 stop5h 23m
United Airlines
Deal found 3/10$350
This American Airlines deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/85:40 am
RST
-
TYS
1 stop4h 38m
American Airlines
Mon 4/138:48 pm
TYS
-
RST
1 stop4h 07m
American Airlines
Deal found 3/11$383
This United Airlines deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/2211:28 am
RST
-
TYS
1 stop4h 31m
United Airlines
Wed 8/266:30 am
TYS
-
RST
1 stop5h 23m
United Airlines
Deal found 3/8$448
This American Airlines deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/75:45 am
RST
-
TYS
1 stop4h 33m
American Airlines
Sun 4/128:48 pm
TYS
-
RST
1 stop4h 07m
American Airlines
Deal found 3/11$458
This American Airlines deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/245:53 am
RST
-
TYS
2 stops9h 28m
American Airlines
Sat 3/288:24 am
TYS
-
RST
2 stops8h 45m
American Airlines
Deal found 3/9$459

Find flight deals from Rochester to Knoxville

Discover tips and strategies to find the most affordable flight options for your journey from Rochester (RST) to Knoxville (TYS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated March 13, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$298
(Delta)

One-way from

$294
(American Airlines)
Provider with most accurate pricing for Rochester-Knoxville McGhee Tyson flight deals.
Search Deals
Provider most trusted by Cheapflights users for Rochester-Knoxville McGhee Tyson flights.
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From Rochester to Knoxville McGhee Tyson
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One-way flight from Rochester to Knoxville McGhee Tyson
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Rochester to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 13, 2026.
Use the filters below to find and compare flights from Rochester to Knoxville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

RochesterKnoxville

RST - TYS

RSTTYS

Rochester

Fri 4/3

6:00 am-4:06 pm

2 stops9h 06m

Knoxville McGhee Tyson

Fri 4/10

6:35 am-10:50 am

1 stop5h 15m

$304

RochesterKnoxville

RST - TYS

RSTTYS

Rochester

Tue 4/14

5:40 am-3:26 pm

2 stops8h 46m

Knoxville McGhee Tyson

Sat 4/18

4:09 pm-11:55 pm

2 stops8h 46m

$309

RochesterKnoxville

RST - TYS

RSTTYS

Rochester

Tue 3/24

4:46 pm-11:03 pm

1 stop5h 17m

Knoxville McGhee Tyson

Sat 3/28

6:35 am-10:50 am

1 stop5h 15m

$318
Quickest round-trip

RochesterKnoxville

RST - TYS

RSTTYS

Rochester

Sat 8/22

11:28 am-4:59 pm

1 stop4h 31m

Knoxville McGhee Tyson

Wed 8/26

6:30 am-10:53 am

1 stop5h 23m

$448

RochesterKnoxville

RST - TYS

RSTTYS

Rochester

Sat 7/25

5:39 am-3:48 pm

2 stops9h 09m

Knoxville McGhee Tyson

Fri 7/31

6:26 pm-11:59 pm

1 stop6h 33m

$458

RochesterKnoxville

RST - TYS

RSTTYS

Rochester

Wed 4/8

5:40 am-6:04 pm

2 stops11h 24m

Knoxville McGhee Tyson

Mon 4/13

5:11 pm-11:55 pm

2 stops7h 44m

$469
Cheapest one-way
Quickest one-way

RochesterKnoxville

RST - TYS

RSTTYS

Rochester

Thu 6/18

5:38 am-12:44 pm

1 stop6h 06m

$294

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/9

Sorted by cheapest first

Compare providers for flights from Rochester to Knoxville

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Rochester to Knoxville in March.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Rochester, Minnesota-Knoxville flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Rochester, Minnesota-Knoxville flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Rochester, Minnesota-Knoxville flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Rochester, Minnesota-Knoxville flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Rochester, Minnesota-Knoxville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Rochester to Knoxville

Have a flexible travel schedule? Discover the best time to fly to Knoxville from Rochester with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Rochester to Knoxville

What is the cheapest month to book a flight from Rochester, Minnesota to Knoxville?

Currently, June is the cheapest month in which you can book a flight from Rochester, Minnesota to Knoxville (average of $49). Flying from Rochester, Minnesota to Knoxville in January is currently the most expensive (average of $248). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Knoxville

Get insights into the airlines that provide service to Knoxville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Knoxville. Reviews last updated March 13, 2026.
Get a feel of what it's like to fly with American Airlines from Rochester to Knoxville by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.1
Good
11,446 reviews

Entertainment

6.9

Comfort

7.2

Food

6.4

Overall

7.1

Crew

7.9

Boarding

7.5

Reviews

1 / 20
2.0
Mediocre

Anonymous,Mar 2026

MIA - SFO

Horrible. When they power flights for other airlines there is nothing they can do to change or accommodate any changes
American Airlines
7.1
Good
11,446 reviews
American Airlines
7.1
Good
11,446 reviews

Entertainment

6.9

Comfort

7.2

Food

6.4

Overall

7.1

Crew

7.9

Boarding

7.5

Reviews

1 / 20
2.0
Mediocre

Anonymous,Mar 2026

MIA - SFO

Horrible. When they power flights for other airlines there is nothing they can do to change or accommodate any changes

Related info for your journey

Find useful and relevant information for your journey from Rochester to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Rochester, Minnesota to Knoxville?

    A quick flight from Rochester, Minnesota to Knoxville can take about 8h 46m. Delta provides one of the quickest options available for as low as $309. The distance between Rochester, Minnesota and Knoxville is about 718 mi. This flight may include one or multiple stops.

  • What is the cheapest airline to fly from Rochester, Minnesota to Knoxville round-trip?

    Flying on American Airlines is currently your cheapest option to Knoxville, with prices starting at $314.

  • Can I find deals for flights from Rochester to Knoxville that include hotel bookings?

    Yes. In addition to deals on Rochester to Knoxville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Rochester to Knoxville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Rochester to Knoxville.

  • Can I find deals for business class flights from Rochester to Knoxville?

    Yes. Cheapflights offers flight deals from Rochester to Knoxville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Rochester, Minnesota to Knoxville?

    Currently, June is the cheapest month in which you can book a flight from Rochester, Minnesota to Knoxville (average of $49). Flying from Rochester, Minnesota to Knoxville in January is currently the most expensive (average of $248). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Cherokee
Crossville
Corbin
Morristown
Bryson City
Alcoa
Murphy
Oak Ridge

Browse thousands of different options on Cheapflights for your next trip

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Top airline flying from Rochester to Knoxville

Discover the top airline that operate flights from Rochester to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 13, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$314Average$398FlexibilityNo cancel feeOn-time71%

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