What are the cheapest airlines flying from Rochester, Minnesota to Knoxville round-trip?

Flying on Delta is currently your cheapest option to Knoxville, with prices starting at $436. Another option worth looking into is American Airlines, starting at $476 round trip.

What is the cheapest day to fly from Rochester, Minnesota to Knoxville?

Travelers seeking maximum savings on their Rochester, Minnesota to Knoxville flight should consider departing on Monday mornings when fares are most often at their lowest. Saturday mornings flights should be avoided if possible as fares are typically the most expensive at this time.

In terms of precipitation, rainfall in Knoxville ranges from 2.7 - 4.8 inches per month. March is typically the wettest month, when rainfall can reach 4.8 in. October is typically the driest time to visit Knoxville when rainfall is around 2.7 in.

If weather is an important factor for your trip to Knoxville, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 78.8 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 39.2 F).

What is the cheapest day to fly round-trip from Rochester, Minnesota to Knoxville?

Travelers have found that booking a Sunday departure is the best way to save up to 68% on the cost of booking your flights compared to booking on days of the week where this route is of high demand.

What is the cheapest time of day to fly from RST to TYS?

Unlike at noon, when flights are generally more expensive, you can save up to 11% on flights from Rochester, Minnesota to Knoxville by exploring options for tickets in the afternoon.

Can I find deals for flights from Rochester to Knoxville that include hotel bookings?

Yes. In addition to deals on Rochester to Knoxville flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Rochester to Knoxville?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Rochester to Knoxville.

Can I find deals for business class flights from Rochester to Knoxville?

Yes. Cheapflights offers flight deals from Rochester to Knoxville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$436+ Flights from Rochester, MN to Knoxville

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Cheap flight deals from Rochester to Knoxville

Round-trip from	$436 (Delta)

From Rochester to Knoxville McGhee Tyson

Search Deals

Find flight deals from Rochester to Knoxville

Cheapest flights from Rochester to Knoxville
Explore the most affordable flight options available from Rochester to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 28, 2025.

Tue 8/124:59 pmRST - TYS

1 stop5h 52mDelta

Sat 8/166:36 amTYS - RST

1 stop5h 21mDelta

Deal found 7/28

$436

Thu 8/76:05 amRST - TYS

1 stop5h 21mAmerican Airlines

Mon 8/115:27 pmTYS - RST

1 stop7h 20mAmerican Airlines

Deal found 7/26

$476

Best flights from Rochester to Knoxville
Discover carefully curated flight deals from Rochester to Knoxville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 28, 2025.

Tue 8/124:59 pmRST - TYS

1 stop5h 52mDelta

Sat 8/166:36 amTYS - RST

1 stop5h 21mDelta

Deal found 7/28

$436

Thu 8/76:05 amRST - TYS

1 stop5h 21mAmerican Airlines

Mon 8/115:27 pmTYS - RST

1 stop7h 20mAmerican Airlines

Deal found 7/26

$476

Last-minute flights from Rochester to Knoxville
Discover last-minute flight deals from Rochester to Knoxville. Data last updated July 28, 2025 and is based on user searches.

Thu 8/76:05 amRST - TYS

1 stop5h 21mAmerican Airlines

Mon 8/1112:56 pmTYS - RST

1 stop5h 59mAmerican Airlines

Deal found 7/27

$476

Tue 8/124:59 pmRST - TYS

1 stop5h 52mDelta

Sat 8/166:36 amTYS - RST

1 stop5h 21mDelta

Deal found 7/28

$436

Fly from

Fly to

Route

Depart

Return

Price

RochesterKnoxville

RST - TYS

RSTTYS

Rochester

Tue 8/12

4:59 pm-11:51 pm

1 stop5h 52m

Knoxville McGhee Tyson

Sat 8/16

6:36 am-10:57 am

1 stop5h 21m

$436

RochesterKnoxville

RST - TYS

RSTTYS

Rochester

Thu 8/7

6:05 am-12:26 pm

1 stop5h 21m

Knoxville McGhee Tyson

Mon 8/11

5:27 pm-11:47 pm

1 stop7h 20m

$476

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/28

Best time to book a flight from Rochester to Knoxville

Have a flexible travel schedule? Discover the best time to fly to Knoxville from Rochester with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Rochester to Knoxville

What is the cheapest month to book a flight from Rochester, Minnesota to Knoxville?

Currently, January is the cheapest month in which you can book a flight from Rochester, Minnesota to Knoxville (average of $295). Flying from Rochester, Minnesota to Knoxville in March is currently the most expensive (average of $376). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Knoxville

Get a feel of what it's like to fly with Delta and American Airlines from Rochester to Knoxville by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.

Delta

8.0

Very good

7,975 reviews

Reviews

1 / 20

10.0

Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Delta

8.0

Very good

7,975 reviews

Delta

8.0

Very good

7,975 reviews

Reviews

1 / 20

10.0

Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

American Airlines

7.2

Good

10,000 reviews

Delta

8.0

Very good

7,975 reviews

Reviews

1 / 20

10.0

Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

What are the cheapest airlines flying from Rochester, Minnesota to Knoxville round-trip?
Flying on Delta is currently your cheapest option to Knoxville, with prices starting at $436. Another option worth looking into is American Airlines, starting at $476 round trip.
Can I find deals for flights from Rochester to Knoxville that include hotel bookings?
Yes. In addition to deals on Rochester to Knoxville flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Rochester to Knoxville?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Rochester to Knoxville.
Can I find deals for business class flights from Rochester to Knoxville?
Yes. Cheapflights offers flight deals from Rochester to Knoxville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Rochester, Minnesota to Knoxville?
Currently, January is the cheapest month in which you can book a flight from Rochester, Minnesota to Knoxville (average of $295). Flying from Rochester, Minnesota to Knoxville in March is currently the most expensive (average of $376). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Morristown

Corbin

Cherokee

Alcoa

Oak Ridge

Murphy

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Alternative routes for Rochester to Knoxville

Complete your trip

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Other flights to Knoxville

Top airline flying from Rochester to Knoxville

Airline	Cheapest	Average	Flexibility	On-time
American Airlines	Cheapest$378	Average$507	FlexibilityNo cancel fee	On-time71%

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$436+ Cheap flights from Rochester, MN to Knoxville (RST - TYS)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/12. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Rochester to Knoxville with Cheapflights

1. Tell us where you want to go

2. Select your favorite providers

3. Compare prices and book

Cheap flight deals from Rochester to Knoxville

Round-trip from

Find flight deals from Rochester to Knoxville

Cheapest flights from Rochester to KnoxvilleExplore the most affordable flight options available from Rochester to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 28, 2025.

Explore the most affordable flight options available from Rochester to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 28, 2025.

Cheapflights Fare Finder

Use the filters below to find and compare flights from Rochester to Knoxville that are best for you.

Best time to book a flight from Rochester to Knoxville

Have a flexible travel schedule? Discover the best time to fly to Knoxville from Rochester with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Rochester to Knoxville

What is the cheapest month to book a flight from Rochester, Minnesota to Knoxville?

Reviews of airlines servicing Knoxville

Get a feel of what it's like to fly with Delta and American Airlines from Rochester to Knoxville by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from Rochester to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

What are the cheapest airlines flying from Rochester, Minnesota to Knoxville round-trip?

Can I find deals for flights from Rochester to Knoxville that include hotel bookings?

How can I find direct flights from Rochester to Knoxville?

Can I find deals for business class flights from Rochester to Knoxville?

What is the cheapest month to book a flight from Rochester, Minnesota to Knoxville?

Traveling to a place near Knoxville?

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Alternative routes for Rochester to Knoxville

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Top airline flying from Rochester to Knoxville

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Travel Smart

Cheapest flights from Rochester to Knoxville
Explore the most affordable flight options available from Rochester to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 28, 2025.